NIH VideoCast - From Germline Genetics to Function: Making Sense of Genome-Wide Association Studies for Pancreatic Cancer Risk

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From Germline Genetics to Function: Making Sense of Genome-Wide Association Studies for Pancreatic Cancer Risk

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Air date:	Friday, March 9, 2018, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 205 (104 Live, 101 On-demand)
Category:	NIH Director's Seminars
Runtime:	00:57:14
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Directors Seminar Series Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States and the seventh world-wide. This seminar will discuss results from genome-wide association studies (GWAS), conducted within the NCI-led Pancreatic Cancer Cohort Consortium. This collaborative effort has identified over 20 common pancreatic cancer risk loci. Genomic and functional characterization of a subset of these loci will be presented. These examples highlight different molecular mechanisms underlying cancer risk and genes found to be important for a wide range of processes including telomere maintenance, RNA surveillance and pancreatic development and homeostasis.

NLM Title:	From germline genetics to function : making sense of genome-wide association studies for pancreatic cancer risk / Laufey Amundadottir.
Author:	Amundadottir, Laufey. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): NIH Directors Seminar Series Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States and the seventh world-wide. This seminar will discuss results from genome-wide association studies (GWAS), conducted within the NCI-led Pancreatic Cancer Cohort Consortium. This collaborative effort has identified over 20 common pancreatic cancer risk loci. Genomic and functional characterization of a subset of these loci will be presented. These examples highlight different molecular mechanisms underlying cancer risk and genes found to be important for a wide range of processes including telomere maintenance, RNA surveillance and pancreatic development and homeostasis.
Subjects:	Carcinoma, Pancreatic Ductal--genetics Genome-Wide Association Study--methods Risk Factors
Publication Types:	Lecture Webcast

NLM Classification:	WI 810
NLM ID:	101724466
CIT Live ID:	27321
Permanent link:	https://videocast.nih.gov/watch=27321

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