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The changing epidemiology of HPV and cervical cancer: from etiology, to validation of prevention methods, to dissemination

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Air date: Wednesday, May 3, 2017, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 337, (138 Live, 199 On-demand)
Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:53:13
Description: NIH Director's Wednesday Afternoon Lecture Series

Over three decades of studies moving from etiology to preventive methods research to guidelines development, Dr. Schiffman has learned some broad lessons about the strengths and weaknesses of epidemiology that he will describe.

He joined the Clinical Genetics Branch in October 2009 to study intensively why HPV is such a powerful carcinogenic exposure, akin to an acquired genetic trait with high penetrance for a cancer phenotype. The main studies in which Dr. Schiffman played a major role in the past 5 years, listed chronologically, include: The Portland Kaiser Cohort; the Taiwan Cohort Study; the Guanacaste Natural History Study; the ASCUS-LSIL Triage Study (ALTS); the Study to Understand Cervical Cancer Early Endpoints and Determinants (SUCCEED/Biopsy); the Costa Rica Vaccine Trial (CVT); the Persistence and Progression (PaP) Study; and Nigeria Project Itoju. These studies overall have related HPV status to outcome for more than 100,000 women.

For more information go to https://oir.nih.gov/wals/2016-2017/changing-epidemiology-hpv-cervical-cancer-etiology-validation-prevention
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NLM Title: The changing epidemiology of HPV and cervical cancer : from etiology, to validation of prevention methods, to dissemination / Mark Schiffman.
Author: Schiffman, Mark.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Director's Wednesday Afternoon Lecture Series Over three decades of studies moving from etiology to preventive methods research to guidelines development, Dr. Schiffman has learned some broad lessons about the strengths and weaknesses of epidemiology that he will describe. He joined the Clinical Genetics Branch in October 2009 to study intensively why HPV is such a powerful carcinogenic exposure, akin to an acquired genetic trait with high penetrance for a cancer phenotype. The main studies in which Dr. Schiffman played a major role in the past 5 years, listed chronologically, include: The Portland Kaiser Cohort; the Taiwan Cohort Study; the Guanacaste Natural History Study; the ASCUS-LSIL Triage Study (ALTS); the Study to Understand Cervical Cancer Early Endpoints and Determinants (SUCCEED/Biopsy); the Costa Rica Vaccine Trial (CVT); the Persistence and Progression (PaP) Study; and Nigeria Project Itoju. These studies overall have related HPV status to outcome for more than 100,000 women.
Subjects: Epidemiologic Studies
Papillomaviridae--pathogenicity
Uterine Cervical Neoplasms--epidemiology
Uterine Cervical Neoplasms--genetics
Publication Types: Lecture
Webcast
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Caption Text: Download Caption File
NLM Classification: WP 480
NLM ID: 101706984
CIT Live ID: 23318
Permanent link: https://videocast.nih.gov/watch=23318