NIH VideoCast - Cell-type-specific STORM superresolution imaging of synaptic cannabinoid signaling

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Cell-type-specific STORM superresolution imaging of synaptic cannabinoid signaling

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Air date:	Monday, June 12, 2017, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 201 (31 Live, 170 On-demand)
Category:	Neuroscience
Runtime:	01:04:23
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Neuroscience Series Seminar Synaptic junctions are major sites of communication in the brain, where chemical messenger molecules transmit information from presynaptic neurons to their postsynaptic partners. The efficacy of synaptic transmission is not constant in time and space. Instead, its plasticity is a fundamental phenomenon underlying information storage and adaptation to environmental stimuli. Although classical neurotransmitters (such as glutamate and GABA) have well characterized principal roles in mediating basal neurotransmission, emerging evidence has revealed that synapses exploit a plethora of additional messenger molecules integrated into sophisticated signaling pathways to accomplish their complex functions. Thus, the major objective of Dr. Katona’s laboratory is to identify new signaling systems regulating synaptic transmission and its plasticity. They aspire to delineate the molecular architecture of these novel pathways and to elucidate their physiological roles. Ultimately, this activity is envisaged to help gain a better understanding of synaptic function and reveal new aspects of impaired synaptic activity in brain disorders. For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx

NLM Title:	Cell-type-specific STORM superresolution imaging of synaptic cannabinoid signaling / Istvan Katona.
Author:	Katona, Istvan. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): NIH Neuroscience Series Seminar Synaptic junctions are major sites of communication in the brain, where chemical messenger molecules transmit information from presynaptic neurons to their postsynaptic partners. The efficacy of synaptic transmission is not constant in time and space. Instead, its plasticity is a fundamental phenomenon underlying information storage and adaptation to environmental stimuli. Although classical neurotransmitters (such as glutamate and GABA) have well characterized principal roles in mediating basal neurotransmission, emerging evidence has revealed that synapses exploit a plethora of additional messenger molecules integrated into sophisticated signaling pathways to accomplish their complex functions. Thus, the major objective of Dr. Katona's laboratory is to identify new signaling systems regulating synaptic transmission and its plasticity. They aspire to delineate the molecular architecture of these novel pathways and to elucidate their physiological roles. Ultimately, this activity is envisaged to help gain a better understanding of synaptic function and reveal new aspects of impaired synaptic activity in brain disorders.
Subjects:	Endocannabinoids--metabolism Receptors, Cannabinoid Synaptic Transmission
Publication Types:	Lecture Webcast

NLM Classification:	QV 126
NLM ID:	101708393
CIT Live ID:	20276
Permanent link:	https://videocast.nih.gov/watch=20276

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