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Drug Metabolism, Pharmacogenetics and the Quest to Personalize HIV Treatment and Prevention

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Air date: Wednesday, April 5, 2017, 2:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 198, (77 Live, 121 On-demand)
Category: Special
Runtime: 00:55:19
Description: 2017 NIGMS Director's Early Career Investigator Lecture

Dr. Bumpus describes how her lab examines the metabolism and distribution of antiretroviral drugs and probes the effects of these metabolites on cellular signaling pathways, with the overarching hypothesis that through integrating a mechanistic understanding of the metabolism and distribution of antiretroviral drugs in cells and tissues, we can move toward being able to predict drug responses in a given individual.
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NLM Title: Drug metabolism, pharmacogenetics, and the quest to personalize HIV treatment and prevention / Namandjé N. Bumpus.
Author: Bumpus, Namandjé N.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Dr. Bumpus describes how her lab examines the metabolism and distribution of antiretroviral drugs and probes the effects of these metabolites on cellular signaling pathways, with the overarching hypothesis that through integrating a mechanistic understanding of the metabolism and distribution of antiretroviral drugs in cells and tissues, we can move toward being able to predict drug responses in a given individual.
Subjects: Anti-HIV Agents--pharmacokinetics
HIV Infections--drug therapy
HIV Infections--genetics
Precision Medicine
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WC 503.2
NLM ID: 101705345
CIT Live ID: 21938
Permanent link: https://videocast.nih.gov/launch.asp?23214