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Rethinking Depression and its Treatment: Perspectives from Studies of Deep Brain Stimulation

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Air date: Monday, June 1, 2015, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 495, (68 Live, 427 On-demand)
Category: Neuroscience
Runtime: 01:00:42
Description: Neuroscience Seminar Series

Dr. Mayberg received a BA in psychobiology from University of California, Los Angeles and an MD from University of Southern California. She is a Board Certified Neurologist, trained at the Neurological Institute of NY at Columbia University and a post-doctoral fellowship in Nuclear Medicine at the Johns Hopkins Medical Institutions.

Dr Mayberg heads a multidisciplinary depression research program dedicated to the study of brain circuits in depression and the effects of various antidepressant treatments measured using a variety of functional and structural imaging tools. The primary focus of the lab to development imaging and physiological based algorithms that will discriminate depressed patient subgroups and optimize treatment selection at all stages of the illness. Imaging findings provided the foundation for development and testing of deep brain stimulation (DBS) of the subcallosal cingulate region (Area 25), a novel intervention for patients with treatment resistant depression.

She was recently named as one of Emory University’s “Game Changers” in recognition of her pioneering DBS research which has been heralded as a one of the first hypothesis-driven treatment strategies for a major mental illness. Clinical trials are now ongoing in both North America and Europe. At Emory, DBS studies aim to refine, optimize and extend the potential of this treatment strategy with experiments designed to characterize and define mechanisms mediating DBS response and to develop biomarkers that will improve patient selection, enhance precision of surgical targeting and optimize stimulation parameters.
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NLM Title: Rethinking depression and its treatment : perspectives from studies of deep brain stimulation / Helen Mayberg.
Author: Mayberg, Helen S.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): The primary focus of the lab to development imaging and physiological based algorithms that will discriminate depressed patient subgroups and optimize treatment selection at all stages of the illness. Imaging findings provided the foundation for development and testing of deep brain stimulation (DBS) of the subcallosal cingulate region (Area 25), a novel intervention for patients with treatment resistant depression. She was recently named as one of Emory University"s "Game Changers" in recognition of her pioneering DBS research which has been heralded as a one of the first hypothesis-driven treatment strategies for a major mental illness. Clinical trials are now ongoing in both North America and Europe. At Emory, DBS studies aim to refine, optimize and extend the potential of this treatment strategy with experiments designed to characterize and define mechanisms mediating DBS response and to develop biomarkers that will improve patient selection, enhance precision of surgical targeting and optimize stimulation parameters.
Subjects: Deep Brain Stimulation
Depressive Disorder, Major--therapy
Electric Stimulation
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WM 207
NLM ID: 101662984
CIT Live ID: 15060
Permanent link: https://videocast.nih.gov/launch.asp?19039