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Family Genomics of Bipolar Disorder

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Air date: Monday, May 4, 2015, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 168, (36 Live, 132 On-demand)
Category: Neuroscience
Runtime: 00:57:10
Description: Neuroscience Seminar Series

Dr. Roach is interested in basic and translational analyses and applications of high-throughput systems-biology data. He is currently focusing on understanding the genetics of complex neurodegenerative diseases, including Huntington's Disease. His research interests include analysis of MHC haplotypes and their relationship to risk and etiology of type 1 diabetes and other autoimmune diseases. Dr. Roach is pioneering approaches for the analysis of whole genome sequencing data in the context of family pedigrees. His past studies have included (1) the systems biology of the macrophage, particularly in its role as an information processing device, at the levels of cell surface receptors, signal transduction, and nuclear regulation, (2) the molecular phylogenetics of vertebrate gene families, particularly those genes relevant to macrophage information processing, and (3) analysis and interpretation of transcript enumeration data, including RNAseq and microarray transcriptomics. Dr. Roach was a co-developer of the pairwise end-sequencing technique. The translational impact of Dr. Roach's research contributes and has contributed to clinical areas including neurodegeneration, autoimmunity, rare genetic diseases, diabetes, inflammation, and vaccine development.
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NLM Title: Family genomics of bipolar disorder / Jared Roach.
Author: Roach, Jared.
National Institutes of Health (U.S.),
Publisher:
Subjects: Bipolar Disorder--genetics
Genetic Predisposition to Disease
Genomics
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WM 207
NLM ID: 101660620
CIT Live ID: 15021
Permanent link: https://videocast.nih.gov/launch.asp?18980