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BACKUP - The Antimicrobial Defense of Drosophila: A Paradigm for Innate Immunity

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Air date: Wednesday, June 29, 2011, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 9 * This only includes stats from October 2011 and forward.
Category: WALS - Wednesday Afternoon Lectures
Runtime: 01:01:09
Description: The last twenty years have experienced an unprecedented advance in our understanding of innate immunity in Metazoans and Plants. Up to the early nineties of the last century, little information had been obtained about pathogen recognition by the innate immune system and about the effector mechanisms induced by invading microorganisms. Drosophila, with its easily tractable genetics, can be credited with having made significant contributions to our present understanding of the basics of innate defenses.

The presentation will review our current understanding, but will also address the many unresolved questions which await further in-depth analysis. A phylogenetic perspective will try to integrate the data obtained by studying Drosophila immunity, into the more general framework of invertebrate and vertebrate immune defenses

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. For more information, visit:
The NIH Director's Wednesday Afternoon Lecture Series
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NLM Title: The antimicrobial defense of Drosophila : a paradigm for innate immunity [electronic resource] / Jules Hoffmann.
Author: Hoffmann, J.
National Institutes of Health (U.S.)
Publisher:
Abstract: (CIT): The last twenty years have experienced an unprecedented advance in our understanding of innate immunity in Metazoans and Plants. Up to the early nineties of the last century, little information had been obtained about pathogen recognition by the innate immune system and about the effector mechanisms induced by invading microorganisms. Drosophila, with its easily tractable genetics, can be credited with having made significant contributions to our present understanding of the basics of innate defenses. The presentation will review our current understanding, but will also address the many unresolved questions which await further in-depth analysis. A phylogenetic perspective will try to integrate the data obtained by studying Drosophila immunity, into the more general framework of invertebrate and vertebrate immune defenses.
Subjects: Anti-Infective Agents--pharmacology
Drosophila--immunology
Immunity, Innate--immunology
Models, Animal
Publication Types: Lectures
Webcasts
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NLM Classification: QW 541
NLM ID: 101566820
CIT Live ID: 10335
Permanent link: https://videocast.nih.gov/launch.asp?16749