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Phytoestrogens, Hedgehog Signaling, ER-alphaKO and ER-betaKO Mice and Prostate Cancer: Good and Bad ERs

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Air date: Wednesday, June 13, 2007, 10:00:00 AM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 121 * This only includes stats from October 2011 and forward.
Category: Special
Runtime: 01:14:35
Description: The NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM) invites you to view its monthly lecture series. The featured guest for June is Dr. Dennis Lubahn, Professor, Biochemistry and Child Health, University of Missouri-Columbia. Dr. Lubahn is also the Director of the Missouri University Center for Phytonutrient and Phytochemical studies. The title of the lecture is "Phytoestrogens, Hedgehog signaling, ER-alphaKO and ER-betaKO mice, and Prostate cancer: Good and bad ERs."

Dr. Lubahn received his Ph.D in Biochemistry from Duke University, Durham, North Carolina. He completed his post-doctoral fellowship at University of North Carolina, Chapel Hill.

Dr. Lubahn's long term research interests involve the understanding of the mechanism of action of the sex steroids and their receptors, in particular the estrogen receptors. His laboratory research goals use estrogen receptor-alpha and estrogen receptor-beta minus mice to look for new estrogen response pathways (i.e. novel estrogen receptors) and to find novel functional roles for the classic estrogen receptor. Other major interests in his laboratory are: 1) The trinucleotide repeat genetic diseases, and 2) The imprinting signals of endocrine disrupters, such as the environmental estrogens, especially those potentially acting via DNA-methylation signaling pathways. Dr. Lubahn was a Pew Scholar in Biomedical Sciences (1989-92). He has served on NIH study sections and he is grantee of the National Cancer Institute (NCI).
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NLM Title: Phytoestrogens, hedgehog signaling, eR-alphaKO and eR-betaKO mice, and prostate cancer : good and bad eRs / Dennis Lubahn.
Author: Lubahn, Dennis B.
Publisher:
Abstract: (CIT): The NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM) invites you to view its monthly lecture series. The featured guest for June is Dr. Dennis Lubahn, Professor, Biochemistry and Child Health, University of Missouri-Columbia. Dr. Lubahn is also the Director of the Missouri University Center for Phytonutrient and Phytochemical studies. The title of the lecture is "Phytoestrogens, Hedgehog signaling, ER-alphaKO and ER-betaKO mice, and Prostate cancer: Good and bad ERs." Dr. Lubahn received his Ph.D in Biochemistry from Duke University, Durham, North Carolina. He completed his post-doctoral fellowship at University of North Carolina, Chapel Hill. Dr. Lubahn's long term research interests involve the understanding of the mechanism of action of the sex steroids and their receptors, in particular the estrogen receptors. His laboratory research goals use estrogen receptor-alpha and estrogen receptor-beta minus mice to look for new estrogen response pathways (i.e. novel estrogen receptors) and to find novel functional roles for the classic estrogen receptor. Other major interests in his laboratory are: 1) The trinucleotide repeat genetic diseases, and 2) The imprinting signals of endocrine disrupters, such as the environmental estrogens, especially those potentially acting via DNA-methylation signaling pathways. Dr. Lubahn was a Pew Scholar in Biomedical Sciences (1989-92). He has served on NIH study sections and he is grantee of the National Cancer Institute (NCI).
Subjects: Estrogen Receptor alpha--therapeutic use
Estrogen Receptor beta--therapeutic use
Hedgehog Proteins
Mice, Knockout
Phytoestrogens--therapeutic use
Prostatic Neoplasms--prevention & control
Publication Types: Lecture
Webcasts
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NLM Classification: WJ 762
NLM ID: 101310924
CIT Live ID: 6006
Permanent link: https://videocast.nih.gov/launch.asp?13890