NIH VideoCast - Biophysics of Neurotransmitter Release at Central Synapses

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Biophysics of Neurotransmitter Release at Central Synapses

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Air date:	Monday, December 17, 2018, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 462 (25 Live, 437 On-demand)
Category:	Neuroscience
Runtime:	00:55:48
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Neuroscience Series Seminar Synaptic contacts mediate the information transfer between neurons. Since the development of the slice patch clamp technique in the late 1980s, it has been shown that different synaptic connections in mammalian brain show remarkably diverse transmission properties and variable levels of synaptic plasticity, which are possibly adapted to specific tasks of information processing. Dr. Sakaba’s lab aims at understanding the mechanisms underlying the diversity among synapses by applying biophysical techniques to several model synapses: the glutamatergic calyx of Held synapse, the GABAergic cerebellar interneuron-Purkinje cell synapse and synaptic connections between cortical neurons. In addition, they study how the observed diversity in synaptic properties as well as membrane properties of the cells affects information processing in cerebellum and cortex. They try to identify the rule of connectivity pattern within a small ensemble of neurons in cerebellum and cortex. For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx

Author:	Takeshi Sakaba, Ph.D., Doshisha University, Japan

CIT Live ID:	28085
Permanent link:	https://videocast.nih.gov/watch=28085

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