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RNA-Triggered Genetic Silencing Mechanisms
Wednesday, October 22, 2003,
3:00:00 PM Time displayed is Eastern Time, Washington DC Local
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The genetic landscape faced by a living cell is constantly changing. Developmental transitions, environmental shifts, and pathogenic invasions lend a dynamic character to both the genome and its activity pattern. A variety of natural mechanisms are utilized by cells adapting to genetic change. These include normal developmental mechanisms and a subset of defense systems for responding to pathogens. At the root of these studies are questions of how a cell can distinguish "self" versus "nonself" and "wanted" versus "unwanted" gene expression.