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Imaging Synaptic Plasticity in Vivo

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Air date: Monday, February 23, 2004, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 165 * This only includes stats from October 2011 and forward.
Category: Neuroscience
Runtime: 01:06:04
Description: Karel Svoboda’s lab studies the electrical and biochemical dynamics of the neocortex and how these dynamics change in response to experience. To approach these questions, the lab studies how the basic units of the network, neurons and their synapses, work within the intact network using sensitive optical tools. Two-photon laser scanning microscopy allows them to detect excitation of single synapses in brain slices and in the intact brain by measuring intracellular calcium accumulation associated with activation of synaptic receptors. Excitation of neuronal elements by focal uncaging of neurotransmitters allows them to probe the connectivity of neural networks.

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Karel Svoboda

NIH Neuroscience Seminar Series
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NLM Title: Imaging synaptic plasticity in vivo / Karel Svoboda.
Author: Svoboda, Karel.
National Institutes of Health (U.S.)
Publisher:
Subjects: Dendrites--physiology
Murinae--physiology
Neocortex--physiology
Neuronal Plasticity--physiology
Synaptic Transmission--physiology
Publication Types: Lectures
Webcasts
Rights: This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
Download: To download this event, select one of the available bitrates:
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NLM Classification: WL 102
NLM ID: 101268369
CIT Live ID: 2566
Permanent link: https://videocast.nih.gov/launch.asp?11837