NIH VideoCast - Beyond DNA: Sequence variation in the RNA

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Beyond DNA: Sequence variation in the RNA

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Air date:	Wednesday, March 2, 2016, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 385 (134 Live, 251 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	00:42:48
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Director's Wednesday Afternoon Lecture DNA is our genetic blueprint. Generally it is expected that RNA sequences are identical to the underlying DNA. However, there are exceptions to this one-to-one relationship, such as the A-to-G RNA editing mediated by ADAR proteins. The Cheung lab uncovered many more sites where RNA sequences differ from the underlying DNA, beyond those mediated by the known RNA-editing mechanisms. Dr. Cheung will describe their findings of RNA-DNA sequence Differences, RDDs, and how their study of juvenile amyotrophic lateral sclerosis is leading to an understanding of RDD formation. For more information go to https://oir.nih.gov/wals

NLM Title:	Beyond DNA : sequence variation in the RNA / Vivian G. Cheung.
Author:	Cheung, Vivian G. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): DNA is our genetic blueprint. Generally it is expected that RNA sequences are identical to the underlying DNA. However, there are exceptions to this one-to-one relationship, such as the A-to-G RNA editing mediated by ADAR proteins. The Cheung lab uncovered many more sites where RNA sequences differ from the underlying DNA, beyond those mediated by the known RNA-editing mechanisms. Dr. Cheung will describe their findings of RNA-DNA sequence differences, RDDs, and how their study of juvenile amyotrophic lateral sclerosis is leading to an understanding of RDD formation.
Subjects:	Base Sequence--genetics DNA RNA Editing RNA Sequence Homology, Nucleic Acid
Publication Types:	Lecture Webcast

NLM Classification:	QU 470
NLM ID:	101680570
CIT Live ID:	17937
Permanent link:	https://videocast.nih.gov/watch=17937

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