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Epigenetic plasticity and somatic memory in reprogrammed hematopoietic progenitors

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Air date: Tuesday, November 1, 2011, 2:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 296, (25 Live, 271 On-demand)
Category: Stem Cell
Runtime: 01:08:29
Description: NIH CRM/SCIG Lecture Series: The Zambidis lab studies the formation of pluripotent stem cells and hematopoietic, endothelial and cardiac differentiation with a focus on the potential therapeutic use of pluripotent stem cell-derived cells. Projects include studying the developmental biology of hematopoiesis as well as improving the differentiation of human embryonic stem cells and human induced pluripotent stem cells to hematopoietic lineages including erythrocytes and lymphocytes; improving the differentiation of human pluripotent stem cells to endothelial cells capable of forming the vasculature system; and improving the differentiation of human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC) to the cardiac lineage.

The research team also studies the developmental biology of gastrulation and cardiogenesis in model organisms and explores potential applications of pluripotent stem cell-derived cardiac in tissue engineering, regenerative medicine, cardiotoxicity screening and novel drug discovery.
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NLM Title: Epigenetic plasticity and somatic memory in reprogrammed hematopoietic progenitors [electronic resource] / Elias Zambidis.
Series: NCRM/SCIG stem cell seminar series
Author: Zambidis, Elias.
National Institutes of Health (U.S.). Stem Cell Interest Group.
Publisher:
Other Title(s): NCRM/SCIG stem cell seminar series
Abstract: (CIT): The Zambidis lab studies the formation of pluripotent stem cells and hematopoietic, endothelial and cardiac differentiation with a focus on the potential therapeutic use of pluripotent stem cell-derived cells. Projects include studying the developmental biology of hematopoiesis as well as improving the differentiation of human embryonic stem cells and human induced pluripotent stem cells to hematopoietic lineages including erythrocytes and lymphocytes; improving the differentiation of human pluripotent stem cells to endothelial cells capable of forming the vasculature system; and improving the differentiation of human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC) to the cardiac lineage. The research team also studies the developmental biology of gastrulation and cardiogenesis in model organisms and explores potential applications of pluripotent stem cell-derived cardiac in tissue engineering, regenerative medicine, cardiotoxicity screening and novel drug discovery.
Subjects: Cell Proliferation
Epigenesis, Genetic
Induced Pluripotent Stem Cells
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: QU 325
NLM ID: 101574466
CIT Live ID: 10746
Permanent link: https://videocast.nih.gov/launch.asp?16942