Elucidation and Pharmacological Targeting of Cellular Dependencies at the Single Cell Level
The event has not started yet...
Wednesday, January 12, 2022, 3:00:00 PM, 1 hour.
| Description: | NIH Wednesday Afternoon Lecture Series
Dr. Califano is the Clyde and Helen Wu Professor of Chemical and Systems Biology, chair of the Department of Systems Biology, and director of the JP Sulzberger Columbia Genome Center at the Columbia University Medical Center. A physicist by training, Califano has taken innovative, systematic approaches to identify the molecular factors that lead to cancer progression and to the emergence of drug resistance at the single-cell level. This entails examination of the complex and tumor-specific molecular interaction networks that determine cancer cell behavior. His lab has shown that master regulators represent critical drivers and tumor dependencies, despite the fact that they are rarely mutated or differentially expressed, thus establishing them as a bona fide new class of therapeutic targets. For more information go to https://oir.nih.gov/wals |
| Stream: | |
| Author: | Andrea Califano, Ph.D., Clyde and Helen Wu Professor of Chemical and Systems Biology, Columbia University Medical Center |
| Runtime: | 1 hour |
| Event ID: | 44190 |