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Mechanisms of Synapse Formation and Axon Regeneration

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Air date: Monday, June 5, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 261, (43 Live, 218 On-demand)
Category: Neuroscience
Runtime: 01:01:41
Description: NIH Neuroscience Series Seminar

The Jin lab research focuses on the molecular genetic mechanisms underlying the development and function of the nervous system using the nematode Caenorhabditis elegans. The transparency, defined anatomy, and rapid life cycle of this organism greatly facilitate their studies at the subcellular resolution. Moreover, the entre cell lineage and connectome are known, enabling functional understanding at deep levels. Through forward genetic screening in combination with multi-layered molecular and cellular manipulations, they are discovering key molecules that play conserved roles in synapse formation, maintenance, and function, as well as those underlying adult axon regeneration. Their goal is to connect the studies of basic mechanisms to the understanding of human neurological disorders and neuronal repair.

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Author: Yishi Jin, Ph.D., Professor and HHMI Investigator, Dept. of Cellular & Molecular Medicine, Division of Bioscience, University of California, San Diego
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CIT Live ID: 20274
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