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Defining and Generating Neuronal Diversity Using Reprogramming

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Air date: Monday, May 22, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 71, (20 Live, 51 On-demand)
Category: Neuroscience
Runtime: 01:03:51
Description: NIH Neuroscience Series Seminar

Dr. Baldwin’s lab is interested in understanding how genetic and epigenetic changes generate cellular diversity, with a particular focus on neurons of the olfactory system and central nervous system. They employ stem cell technologies such as cloning and induced pluripotency, gene targeting in mice, molecular biology and advanced imaging techniques to identify rules governing cell identity and cellular diversification. They are also interested in using induced pluripotent stem cells and neurons derived from them to generate in vitro models of human neurological diseases.

Their current research focus includes 1) Generating Mice from iPS Cells; 2) Control of genome stability during reprogramming and in iPSCs; 3) Generating Cell Lines from Neurons; 4) Modeling Neurological Disease Using Reprogramming; 5) Generating Neuronal Diversity and Connectivity in the Olfactory System.

For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx
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NLM Title: Defining and generating neuronal diversity using reprogramming / Kristin Baldwin.
Author: Baldwin, Kristin.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Dr. Baldwin's lab is interested in understanding how genetic and epigenetic changes generate cellular diversity, with a particular focus on neurons of the olfactory system and central nervous system. They employ stem cell technologies such as cloning and induced pluripotency, gene targeting in mice, molecular biology and advanced imaging techniques to identify rules governing cell identity and cellular diversification. They are also interested in using induced pluripotent stem cells and neurons derived from them to generate in vitro models of human neurological diseases. Their current research focus includes 1. Generating Mice from iPS Cells; 2. Control of genome stability during reprogramming and in iPSCs; 3. Generating Cell Lines from Neurons; 4. Modeling Neurological Disease Using Reprogramming; 5. Generating Neuronal Diversity and Connectivity in the Olfactory System.
Subjects: Cellular Reprogramming
Neuronal Plasticity--physiology
Neurons--cytology
Transcription Factors--genetics
Publication Types: Lectures
Webcasts
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NLM Classification: WL 102
NLM ID: 101707003
CIT Live ID: 20272
Permanent link: https://videocast.nih.gov/launch.asp?23305