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Trans-Agency Blood Brain Interface Workshop 2016 (Day 1)

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Air date: Tuesday, June 7, 2016, 8:00:00 AM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 329 (151 Live, 178 On-demand)
Category: Conferences
Runtime: 07:13:22
Description: The goal of the 2016 Trans-Agency Blood Brain Interface Workshop is to bring together experts to examine key challenges and proposed recommendations associated with the interface between the circulatory system and the brain. The workshop will cut across the interface and include sessions on upstream blood biomarkers as well as targeted drug delivery, highlighting the potential therapeutic role of exosomes for diagnostic applications as well as targeted drug delivery, and brain sequelae that release biomarkers into the circulation. A common theme that has emerged on both sides of the interface is the role of the immune system and the inflammasome. The Blood-Brain Barrier is an under-represented scientific area at NHLBI and there is a need for stimulation of this space in the blood sciences. There is a growing body of work around exosomes and extracellular vesicle transport and that these microvesicles can be harnessed for diagnostic applications as well as targeted drug delivery. Developments in microphysiological platform technologies are also making future diagnostic strategies possible. The workshop will include experts in the Blood Sciences, BBB biology, BBB modeling and Technology development including exosome therapeutics, platform technologies, and nanotechnology. Current NIH efforts in these areas can be leveraged for targeted therapeutic development.
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NLM Title: Trans-Agency Blood Brain Interface Workshop 2016 / NHLBI/NCI/DOD.
Author: Trans-Agency Blood Brain Interface Workshop :
National Heart, Lung, and Blood Institute,
National Cancer Institute (U.S.),
United States. Department of Defense,
Publisher:
Abstract: (CIT): The goal of the 2016 Trans-Agency Blood Brain Interface Workshop is to bring together experts to examine key challenges and proposed recommendations associated with the interface between the circulatory system and the brain. The workshop will cut across the interface and include sessions on upstream blood biomarkers as well as targeted drug delivery, highlighting the potential therapeutic role of exosomes for diagnostic applications as well as targeted drug delivery, and brain sequelae that release biomarkers into the circulation. A common theme that has emerged on both sides of the interface is the role of the immune system and the inflammasome. The Blood-Brain Barrier is an under-represented scientific area at NHLBI and there is a need for stimulation of this space in the blood sciences. There is a growing body of work around exosomes and extracellular vesicle transport and that these microvesicles can be harnessed for diagnostic applications as well as targeted drug delivery. Developments in microphysiological platform technologies are also making future diagnostic strategies possible. The workshop will include experts in the Blood Sciences, BBB biology, BBB modeling and Technology development including exosome therapeutics, platform technologies, and nanotechnology. Current NIH efforts in these areas can be leveraged for targeted therapeutic development.
Subjects: Blood-Brain Barrier--physiology
Brain--blood supply
Drug Delivery Systems
Exosomes--physiology
Publication Types: Congress
Webcast
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Caption Text: Download Caption File
NLM Classification: WL 200
NLM ID: 101686956
CIT Live ID: 18500
Permanent link: https://videocast.nih.gov/watch=18500