Skip Navigation


CIT can broadcast your seminar, conference or meeting live to a world-wide audience over the Internet as a real-time streaming video. The event can be recorded and made available for viewers to watch at their convenience as an on-demand video or a downloadable file. CIT can also broadcast NIH-only or HHS-only content.

Programmable on-chip DNA compartments as Artificial Cells

Loading video...

259 Views  
   
Air date: Wednesday, November 19, 2014, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 259, (93 Live, 166 On-demand)
Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:49:11
Description: Wednesday Afternoon Lecture Series

For his WALS lecture, Dr. Bar-Ziv will discuss the assembly of two-dimensional DNA compartments that are fabricated in silicon. These artificial cells are capable of metabolism, programmable protein synthesis, and communication. Metabolism is maintained by continuous diffusion of nutrients and products through a thin capillary, connecting protein synthesis in the DNA compartment with the environment. The Bar-Ziv laboratory programmed protein-expression cycles, autoregulated protein levels, and a signaling-expression gradient, equivalent to a morphogen, in an array of interconnected compartments at the scale of an embryo. Gene expression in the DNA compartment reveals a rich, dynamic system that is controlled by geometry, offering a means for studying biological networks outside a living cell.

For more information go to http://wals.od.nih.gov
Debug: Show Debug
NLM Title: Programmable on-chip DNA compartments as artificial cells / Roy Bar-Ziv.
Author: Bar-Ziv, Roy.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Wednesday Afternoon Lecture Series For his WALS lecture, Dr. Bar-Ziv will discuss the assembly of two-dimensional DNA compartments that are fabricated in silicon. These artificial cells are capable of metabolism, programmable protein synthesis, and communication. Metabolism is maintained by continuous diffusion of nutrients and products through a thin capillary, connecting protein synthesis in the DNA compartment with the environment. The Bar-Ziv laboratory programmed protein-expression cycles, autoregulated protein levels, and a signaling-expression gradient, equivalent to a morphogen, in an array of interconnected compartments at the scale of an embryo. Gene expression in the DNA compartment reveals a rich, dynamic system that is controlled by geometry, offering a means for studying biological networks outside a living cell.
Subjects: Artificial Cells
DNA
Silicon
Publication Types: Lecture
Webcasts
Download: To download this event, select one of the available bitrates:
[64k]  [150k]  [240k]  [440k]  [740k]  [1040k]  [1240k]  [1440k]  [1840k]    How to download a Videocast
Caption Text: Download Caption File
NLM Classification: QU 58.5
NLM ID: 101647976
CIT Live ID: 15136
Permanent link: https://videocast.nih.gov/launch.asp?18745