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The Genetics of Tauopathies: Modifying Genes and the Mechanisms they Reveal

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Air date: Monday, October 4, 2010, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 171 * This only includes stats from October 2011 and forward.
Category: Neuroscience
Runtime: 01:07:15
Description: Dr. Schellenberg has worked on the genetics of Alzheimer’s disease, starting with ground-breaking research on early-onset familial Alzheimer’s disease followed by work on late-onset dementia which is where much of his current effort is focused. He is founder and head of the Alzheimer’s Disease Genetics Consortium supported by the National Institute on Aging. He also worked on the genetics of aging and his group identified the gene for Werner’s Syndrome, a premature aging syndrome. In addition, he is working on the molecular genetics on other neurodegenerative disorders related to Alzheimer’s disease with a focus on frontotemporal dementia, Guam amyotrophic lateral sclerosis/parkinsonism dementia complex and progressive supranuclear palsy. This work includes using both invertebrate and vertebrate model organisms to study tauopathies.

Dr. Schellenberg leads the Alzheimer’s Disease Genetics Consortium (ADGC), which is comprised of a group of investigators who are using genome-wide association analysis methods to identify Alzheimer’s disease. The Consortium works with the 29 National Institute on Aging funded Alzheimer’s Disease Centers to collect samples for analysis. The ADGC was formed in 2007 and fully funded in April, 2009. He is also working on unraveling the genetics of autism, a complex neurodevelopmental disorder. He participates in the Autism Genome Project consortium. His current efforts focus on deep sequencing of genes suspected of being involved in autism risk.

NIH Neuroscience Seminar Series
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NLM Title: The genetics of tauopathies : modifying genes and the mechanisms they reveal / Gerard Schellenberg.
Author: Schellenberg, Gerard.
National Institutes of Health (U.S.)
Subjects: Alzheimer Disease--genetics
Supranuclear Palsy, Progressive--genetics
tau Proteins--genetics
Publication Types: Lecture
Download: To download this event, select one of the available bitrates:
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NLM Classification: WL 359
NLM ID: 101549173
CIT Live ID: 9482
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