NIH VideoCast - Strategies or Cognitive Translation from Mouse to Human: Some Examples from Alzheimer's Disease, Huntington's Disease, and Schizophrenia

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Strategies or Cognitive Translation from Mouse to Human: Some Examples from Alzheimer's Disease, Huntington's Disease, and Schizophrenia

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Air date:	Monday, September 20, 2010, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 190 * This only includes stats from October 2011 and forward.
Category:	Neuroscience
Runtime:	01:16:59
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Dr. Bussey's lab is interested in the neurobiology of visual learning, memory and perception. Their research is conducted at two different levels of brain organization, the anatomical systems and neural network levels. The former is concerned with brain structures and their function and relationship to one another. The latter is concerned mainly with neocortical circuitry and the action of neurotransmitters. These two levels are, they think, the appropriate ones at which to begin to address the two ‘big questions’ in which they are interested, namely 'How are visual memory and perception organized in the brain?' and 'What are the mechanisms of visual memory and perception in the brain?' The research carried out in the CSNLab centres around two fundamental questions: How is visual cognition organized in the brain? And what are the mechanisms of visual cognition in the brain? These pure research questions about the intact brain are complemented by a single ‘big question’ pertaining to damaged brains: How can we better understand the effects of brain damage and pathology, with a view toward therapy? They are working toward an answer to these questions through a programme of theoretically-driven experimental research using both healthy subjects and brain-damaged populations. Major areas of research are Alzheimer's disease, Schizophrenia and Huntington's disease.The CSNLab has been funded by grants from the Alzheimer’s Research Trust, BBSRC, Wellcome Trust, MRC and the High Q Foundation, and operates under the auspices of the MRC Wellcome Trust Behavioural and Clinical Neuroscience Institute. NIH Neuroscience Seminar Series

NLM Title:	Strategies for cognitive translation from mouse to human : some examples from Alzheimer's disease, Huntington's disease, and schizophrenia / Timothy J. Bussey.
Author:	Bussey, Timothy J. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Dr. Bussey's lab is interested in the neurobiology of visual learning, memory and perception. Their research is conducted at two different levels of brain organization, the anatomical systems and neural network levels. The former is concerned with brain structures and their function and relationship to one another. The latter is concerned mainly with neocortical circuitry and the action of neurotransmitters. These two levels are, they think, the appropriate ones at which to begin to address the two "big questions" in which they are interested, namely 'How are visual memory and perception organized in the brain?' and 'What are the mechanisms of visual memory and perception in the brain?' The research carried out in the CSNLab centres around two fundamental questions: How is visual cognition organized in the brain? And what are the mechanisms of visual cognition in the brain? These pure research questions about the intact brain are complemented by a single "big question" pertaining to damaged brains: How can we better understand the effects of brain damage and pathology, with a view toward therapy? They are working toward an answer to these questions through a programme of theoretically-driven experimental research using both healthy subjects and brain-damaged populations. Major areas of research are Alzheimer's disease, Schizophrenia and Huntington's disease.The CSNLab has been funded by grants from the Alzheimer"s Research Trust, BBSRC, Wellcome Trust, MRC and the High Q Foundation, and operates under the auspices of the MRC Wellcome Trust Behavioural and Clinical Neuroscience Institute.
Subjects:	Alzheimer Disease--physiopathology Cognition Disorders--physiopathology Disease Models, Animal Huntington Disease--physiopathology Schizophrenia--physiopathology
Publication Types:	Lecture Webcast
NLM Classification:	WT 155
NLM ID:	101546214
CIT Live ID:	9480
Permanent link:	https://videocast.nih.gov/watch=9480

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