The course includes presentation of patients, pathology, diagnosis and therapy in the context of major disease problems and current research. Primarily directed toward Ph.D. students, fellows, and staff, it is also of interest to medical students and clinicians. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components which are presented by NIH staff and outside invitees.
Demystifying medicine. Malaria : big killer and big advances / [Thomas E. Wellems, John B. Robbins].
Wellems, Thomas E. National Institutes of Health (U.S.)
Part of the Demystifying Medicine series at the National Institutes of Health (NIH), this lecture by Thomas E. Wellems of the National Institute of Allergy and Infectious Diseases (NIAID) and John B. Robbins of the National Institute of Child Health and Human Development (NICHHD) focuses on: 1) public health measures to combat malaria, and 2) efforts to develop an effective vaccine. Wellems's presentation, "Malaria: History, Burden, and State of the Science" begins with a patient case study and includes a look at the use of bed-netting to control infection, the appearance of chloroquine resistance and the mutations that lead to it, and the importance of alternatives to chloroquine in regions where malaria is still prevalent. Robbins notes that there is good potential for cheap, easy-to-manufacture vaccines that could apply at different stages of transmission and illness. He emphasizes that malaria in Africa is a major cause of stunted growth in children, and renders infected children susceptible to other maladies including pneumococcal meningitis. Thus, vaccine development is critical to prevent long-term health impacts in the population.
Malaria Vaccines Malaria--drug therapy Malaria--prevention & control