NIH VideoCast - Demystifying Medicine — Sleep and Perchance to Dream: Mechanisms and Management

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Demystifying Medicine — Sleep and Perchance to Dream: Mechanisms and Management

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Air date:	Tuesday, April 30, 2024, 4:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 345 (169 Live, 176 On-demand)
Category:	Demystifying Medicine
Runtime:	01:52:04
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	The next 'Demystifying Medicine' will comprise complementary lectures on the genetic mechanisms of sleep as revealed through observations of Drosophila and new techniques to measure the human brain during slumber. The speakers are Susan Harbison, Ph.D. (NHLBI) and Dante Picchioni, Ph.D. (NINDS). This penultimate set of lectures in our 2024 season will be held in th.e Lipsett Amphitheater, Building 10, from 4:00 to 6:00 p.m. ET The reason for sleep remains a mystery, as it deprives an animal from otherwise foraging for food, mating, are avoiding predators. Yet it is clearly needed for physical and mental health. And nearly every animal sleeps. Pioneering work has recognized that sleep in the genetic model organism Drosophila melanogaster has similarities to mammalian sleep. This set of 'Demystifying Medicine' lectures will discuss some of the ways in which Drosophila can be used to identify genetic networks for sleep, coupled with exciting new neuroimaging techniques with high spatial resolution being developed at the NIH to facilitate the linkage of the various human brain states that occur during sleep to the functions of sleep itself. Our first speaker, Dr. Harbison, leads the NHLBI Laboratory of Systems Genetics. Her research has associated sleep characteristics in natural populations with molecular data across populations, environments, and species. Her lab's aim is to look beyond single genes to identify gene networks that will illuminate the function of sleep as well as the degree of conservation across species. Our second speaker, Dr. Picchioni, is a scientist in the NINDS Advanced MRI Section. He will discuss functional magnetic resonance imaging as a means to measure the human brain during sleep. He will discuss an example of a conventional sleep disorder, narcolepsy, and also the role sleep abnormalities play in posttraumatic stress disorder. The Demystifying Medicine Series, jointly sponsored by FAES and NIH, includes presentations on pathology, diagnosis, and therapy in the context of major disease problems and current research. Primarily directed toward PhD students, clinicians and program managers, this series is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. All students, trainees, fellows, and staff are welcome to participate. For more information go to https://demystifyingmedicine.od.nih.gov

Author:	Susan Harbison (NHLBI) and Dante Picchioni (NINDS)

CIT Live ID:	54047
Permanent link:	https://videocast.nih.gov/watch=54047

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