NIH VideoCast - NIH FDA COVID-19 SIG Lecture Series- Professor Wendy Barclay

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NIH FDA COVID-19 SIG Lecture Series- Professor Wendy Barclay

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Air date:	Thursday, January 18, 2024, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 318 (206 Live, 112 On-demand)
Category:	COVID-19
Runtime:	00:57:51
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Dr. Barclay joined Imperial College in May 2007, moving with her research group from the University of Reading where she had previously been based since 1995. She had graduated in Natural Sciences from Cambridge University and had undertaken my PhD at the Common Cold Unit, Salisbury under the joint supervision of Dr David Tyrrell and Dr Fred Brown, studying the human immune response to rhinovirus. Dr. Barclay acquired molecular virology skills as a postdoctoral fellow first in the laboratories of Professor Jeff Almond at Reading and then working with Dr Peter Palese at the Mount Sinai School of Medicine, New York.Dr. Barclay’s expertise is in the field of respiratory viruses, in particular influenza viruses. Her studies aim to understand the molecular and cellular basis of the pathogenesis, host range restrictions and transmissibility of influenza viruses. The approach includes the generation of recombinant viruses with defined mutations. This strategy has contributed to the production of novel influenza pandemic vaccines. In principle, the work employs the most appropriate virus strains and relevant cell or animal models. Primary influenza clinical strains are obtained through a long-standing collaboration with the Health Protection Agency, and viruses are studied on primary human airway cells and in ferrets. Translational aspects include analysing mode of action and resistance mechanisms of antiviral compounds, and characterization of novel cell substrates and attenuated virus backbones for influenza vaccines. The laboratory is funded by MRC, BBSRC, the Wellcome Trust and commercial bodies. For more information go to https://oir.nih.gov/sigs/covid-19-scientific-interest-group

Author:	Professor Wendy Barclay

CIT Live ID:	53966
Permanent link:	https://videocast.nih.gov/watch=53966

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