CIT can broadcast your seminar, conference or meeting live to a world-wide audience over the Internet
as a real-time streaming video. The event can be recorded and made available for viewers to watch at
their convenience as an on-demand video or a downloadable file. CIT can also broadcast NIH-only or HHS-only content.
Outer Membrane Biogenesis in Gram-Negative Bacteria
Wednesday, January 10, 2007,
3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Total views: 112 * This only includes stats from October 2011 and forward.
The outer membrane (OM) of Gram-negative bacteria functions as a protective barrier. It is unusual because the OM bilayer is asymmetric; the inner leaflet is composed of phospholipids, but the outer leaflet is made of lipopolysaccharide (LPS). Two kinds of proteins are found in the OM.
Lipoproteins are inserted into the inner leaflet of the OM by posttranslationally attached lipid moieties. Integral OM proteins are Beta-barrel proteins (OMPs). All of the components of the OM are synthesized inside the cell. They must be transported to, and assembled in the OM in the correct orientation to maintain barrier function, and all of this takes place outside the cytoplasm where there is no obvious energy source, such as ATP.