NIH VideoCast - CCR Grand Rounds: Studying Precision Oncology Past by Mining a Clinical Trials Database and Identifying Future Opportunities from Single-Cell Analysis

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CCR Grand Rounds: Studying Precision Oncology Past by Mining a Clinical Trials Database and Identifying Future Opportunities from Single-Cell Analysis

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Air date:	Friday, March 31, 2023, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 219 (158 Live, 61 On-demand)
Category:	Special
Runtime:	01:07:14
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	CCR Grand Rounds “Studying Precision Oncology Past by Mining a Clinical Trials Database and Identifying Future Opportunities from Single-Cell Analysis” Alejandro A. Schäffer, Ph.D.Staff Scientist, Cancer Data Science LaboratoryCenter for Cancer Research, NCI Friday, March 31, 202312:00–1:00 p.m.Lipsett Amphitheater (Masks required) Also available to view via NIH Videocast. Alejandro Schäffer, Ph.D., was born in Montevideo, Uruguay, and emigrated with his parents to the United States. He received his B.S. in Applied Mathematics and his M.S. in Mathematics from Carnegie Mellon University in 1983. He received his Ph.D. in Computer Science from Stanford University in 1988, focusing on algorithms and theoretical computer science. In 1992, he switched his research focus to software for genetics. He is best known for leading the development of the genetic linkage analysis package FASTLINK and for doing the implementation of the PSI-BLAST module of the sequence analysis package BLAST. The 1997 paper describing PSI-BLAST and other algorithmic improvements to BLAST is one of the 100 most cited scientific papers of all time. He has also carried out genomic data analysis as a member of large teams doing medical genetics studies, especially studies identifying genes that when mutated cause human primary immunodeficiencies. In 1999, Dr. Schäffer co-authored one of the first papers in tumor phylogenetics, now an active area of research in cancer genomics. Dr. Schäffer has been a computer scientist at the National Institutes of Health since 1996, first at the National Center for Human Genome Research, which became the National Human Genome Research Institute, from 1996 to 1998, second at the National Center for Biotechnology Information from 1998 to 2018 and currently at the Cancer Data Science Laboratory in NCI which he joined on October 28, 2018. In the Cancer Data Science Laboratory, Dr. Schäffer is guided by the Lab Chief, Dr. Eytan Ruppin, to apply his experience in algorithms, biological sequence analysis, genetic data analysis and immunology to address research questions in cancer genomics.

NLM Title:	Studying precision oncology past by mining a clinical trials database and identifying future opportunities from single-cell analysis / Alejandro A. Schäffer.
Author:	Schäffer, Alejandro A. Center for Cancer Research (National Cancer Institute (U.S.)),
Publisher:
Abstract:	(CIT): CCR Grand Rounds"Studying Precision Oncology Past by Mining a Clinical Trials Database and Identifying Future Opportunities from Single-Cell Analysis"Alejandro A. Schäffer, Ph.D.Staff Scientist, Cancer Data Science LaboratoryCenter for Cancer Research, NCIFriday, March 31, 202312:00-1:00 p.m.Lipsett Amphitheater(Masks required)Also available to view via NIH Videocast.Alejandro Schäffer, Ph.D., was born in Montevideo, Uruguay, and emigrated with his parents to the United States. He received his B.S. in Applied Mathematics and his M.S. in Mathematics from Carnegie Mellon University in 1983. He received his Ph.D. in Computer Science from Stanford University in 1988, focusing on algorithms and theoretical computer science. In 1992, he switched his research focus to software for genetics. He is best known for leading the development of the genetic linkage analysis package FASTLINK and for doing the implementation of the PSI-BLAST module of the sequence analysis package BLAST. The 1997 paper describing PSI-BLAST and other algorithmic improvements to BLAST is one of the 100 most cited scientific papers of all time. He has also carried out genomic data analysis as a member of large teams doing medical genetics studies, especially studies identifying genes that when mutated cause human primary immunodeficiencies. In 1999, Dr. Schäffer co-authored one of the first papers in tumor phylogenetics, now an active area of research in cancer genomics. Dr. Schäffer has been a computer scientist at the National Institutes of Health since 1996, first at the National Center for Human Genome Research, which became the National Human Genome Research Institute, from 1996 to 1998, second at the National Center for Biotechnology Information from 1998 to 2018 and currently at the Cancer Data Science Laboratory in NCI which he joined on October 28, 2018. In the Cancer Data Science Laboratory, Dr. Schäffer is guided by the Lab Chief, Dr. Eytan Ruppin, to apply his experience in algorithms, biological sequence analysis, genetic data analysis and immunology to address research questions in cancer genomics.
Subjects:	Antineoplastic Combined Chemotherapy Protocols Clinical Trials as Topic Databases as Topic Neoplasms--drug therapy Single-Cell Analysis
Publication Types:	Lecture Webcast

NLM Classification:	QZ 267
NLM ID:	9918592678306676
CIT Live ID:	49064
Permanent link:	https://videocast.nih.gov/watch=49064

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