Autoinflammatory Disease and the Human Condition

Air date:	Wednesday, June 7, 2023, 2:00:00 PM Time displayed is Eastern Time, Washington DC Local
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Description:	This is the annual WALS Mider Lecture. Former NHGRI Scientific Director, and NIH Distinguished Investigator in the Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch that has been with NIH since 1985, Dr. Dan Kastner’s career at the NIH his research has focused on using genetic and genomic strategies to understand inherited disorders of inflammation, often stimulated by patients with relatively rare disorders seen at the NIH Clinical Center hospital. This work has provided detailed molecular explanations for these illnesses, has provided the conceptual basis for highly effective targeted therapies, and has informed our understanding of more common illnesses. Kastner’s group also proposed the now widely accepted overarching concept of autoinflammatory disease to denote disorders of the evolutionarily ancient innate branch of the human immune system. Dr. Kastner has won several awards and honors, including election to the National Academy of Sciences in 2010 and to the National Academy of Medicine in 2012, recognition as Federal Employee of the Year in 2018, and the Ross Prize in Molecular Medicine in 2019. For more information go to https://oir.nih.gov/wals
Author:	Dan Kastner, M.D., Ph.D., NIH NHGRI
Runtime:	1 hour

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