NIH VideoCast - Molecular Origami: The Delicate Art of Protein Folding and Misfolding and Its Relevance to Health and Disease

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Molecular Origami: The Delicate Art of Protein Folding and Misfolding and Its Relevance to Health and Disease

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Air date:	Wednesday, September 21, 2022, 2:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 558 (185 Live, 373 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:03:04
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Director’s Wednesday Afternoon Lecture Series Judith Frydman is a biochemist and the Donald Kennedy Chair in the School of Humanities & Sciences and Professor of Genetics at Stanford University. Her research focuses on protein folding. Her laboratory discovered the molecular chaperone TRiC/CCT and determined its mechanism and function for protein folding. She was elected as a Fellow of the American Academy of Arts & Sciences in 2018 and as a Fellow of the Biophysical Society in 2019. In 2017, she was given the American Society for Biochemistry and Molecular Biology–Merck Award. She is an editor of the Journal of Cell Biology. In 2021, she was elected member of the U. S. National Academy of Sciences. The long term goal of our research is to understand how proteins fold in living cells. The Frydman lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies. For more information go to https://oir.nih.gov/wals

Author:	Judith Frydman, Ph.D., Donald Kennedy Chair, School of Humanities and Sciences; Professor of Genetics, Stanford University

CIT Live ID:	45984
Permanent link:	https://videocast.nih.gov/watch=45984

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