NIH VideoCast - WALS and Demystifying Medicine - Tiny Technologies and Medicine: From Hepatic Tissue Engineering to Cancer Nanotechnology

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WALS and Demystifying Medicine - Tiny Technologies and Medicine: From Hepatic Tissue Engineering to Cancer Nanotechnology

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Air date:	Tuesday, March 22, 2022, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 444 (213 Live, 231 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:09:15
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Special Tuesday WALS Lecture, part of Demystifying Medicine. Dr. Bhatia is director of the Marble Center for Cancer Nanomedicine at the Koch Institute and the John J. and Dorothy Wilson Professor of Health Sciences and Technology and of Electrical Engineering and Computer Science. She also is a Howard Hughes Medical Institute Investigator and an elected member of the National Academy of Sciences, the National Academy of Engineering, the National Academy of Medicine, the National Academy of Inventors, and the American Academy of Arts and Science. The Bhatia Laboratory studies how micro- and nanoscale systems can be deployed to understand, diagnose, and treat human disease. Dr. Bhatia will describe her progress in two application areas: liver disease and cancer. In the area of the liver, her lab is developing microtechnology tools to understand how ensembles of cells coordinate to produce tissues with emergent properties in the body. They have used this understanding to fabricate human micro-liver tissues in both '2D' and '3D' formats that enable us to study the pathogenesis of relapsing malaria and liver regeneration. In the area of cancer, the lab is developing nanotechnology tools to meet the challenge of delivering cargo into the tumor microenvironment where transport is dominated by diffusion. Their strategy is to design nanotechnologies that emulate nature's mechanisms of homing, activation, and amplification to deliver cytotoxic drugs, diagnostic tools, imaging agents, and nucleic acids to tumors. For more information go to https://oir.nih.gov/wals

NLM Title:	Demystifying medicine. Tiny technologies and medicine : from hepatic tissue engineering to cancer nanotechnology / Sangeeta Bhatia.
Author:	Bhatia, Sangeeta. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): Special Tuesday WALS Lecture, part of Demystifying Medicine. Dr. Bhatia is director of the Marble Center for Cancer Nanomedicine at the Koch Institute and the John J. and Dorothy Wilson Professor of Health Sciences and Technology and of Electrical Engineering and Computer Science. She also is a Howard Hughes Medical Institute Investigator and an elected member of the National Academy of Sciences, the National Academy of Engineering, the National Academy of Medicine, the National Academy of Inventors, and the American Academy of Arts and Science. The Bhatia Laboratory studies how micro- and nanoscale systems can be deployed to understand, diagnose, and treat human disease. Dr. Bhatia will describe her progress in two application areas: liver disease and cancer. In the area of the liver, her lab is developing microtechnology tools to understand how ensembles of cells coordinate to produce tissues with emergent properties in the body. They have used this understanding to fabricate human micro-liver tissues in both "2D" and "3D" formats that enable us to study the pathogenesis of relapsing malaria and liver regeneration. In the area of cancer, the lab is developing nanotechnology tools to meet the challenge of delivering cargo into the tumor microenvironment where transport is dominated by diffusion. Their strategy is to design nanotechnologies that emulate nature"s mechanisms of homing, activation, and amplification to deliver cytotoxic drugs, diagnostic tools, imaging agents, and nucleic acids to tumors.
Subjects:	Liver Regeneration Neoplasms--therapy Theranostic Nanomedicine Tissue Engineering Tumor Microenvironment
Publication Types:	Lecture Webcast

NLM Classification:	QT 36.5
NLM ID:	9918384669306676
CIT Live ID:	44231
Permanent link:	https://videocast.nih.gov/watch=44231

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