NIH VideoCast - A Vision Engaging Pharmacokinetic Strategies to Treat Substance Abuse Disorders and Overdose

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A Vision Engaging Pharmacokinetic Strategies to Treat Substance Abuse Disorders and Overdose

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Air date:	Wednesday, November 10, 2021, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 293 (147 Live, 146 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:00:12
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Wednesday Afternoon Lecture Series Dr. Janda is the Ely R. Callaway Jr. Professor of Chemistry and director or the Worm Institute for Research & Medicine at Scripps Research. His research blends medicinal chemistry and molecular biology with neuropharmacology and immunology. Our ability to aid individuals with a substance use disorder is handicapped by the lack of sufficient treatment modalities. Traditional, small-molecule approaches have only been marginally successful. Biologics-based therapeutics offer an alternative to customary pharmacodynamic approaches for treating both substance use disorders as well as lethality threats from many of these drugs. Dr. Janda will discuss the history and basic tenets on vaccination as well as how vaccination can alter the pharmacokinetic properties of drugs without burdening the recipient with untoward side effects. The lecture will detail the chemistry, immunology, and behavioral findings from vaccines against opioids, including heroin and the synthetic opioids fentanyl and carfentanil, as well as a bacterial source to treat nicotine substance disorders and poisoning. For more information go to https://oir.nih.gov/wals

NLM Title:	A vision engaging pharmacokinetic strategies to treat substance abuse disorders and overdose / Kim Janda.
Author:	Janda, Kim D. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): Wednesday Afternoon Lecture Series Dr. Janda is the Ely R. Callaway Jr. Professor of Chemistry and director or the Worm Institute for Research & Medicine at Scripps Research. His research blends medicinal chemistry and molecular biology with neuropharmacology and immunology. Our ability to aid individuals with a substance use disorder is handicapped by the lack of sufficient treatment modalities. Traditional, small-molecule approaches have only been marginally successful. Biologics-based therapeutics offer an alternative to customary pharmacodynamic approaches for treating both substance use disorders as well as lethality threats from many of these drugs. Dr. Janda will discuss the history and basic tenets on vaccination as well as how vaccination can alter the pharmacokinetic properties of drugs without burdening the recipient with untoward side effects. The lecture will detail the chemistry, immunology, and behavioral findings from vaccines against opioids, including heroin and the synthetic opioids fentanyl and carfentanil, as well as a bacterial source to treat nicotine substance disorders and poisoning.
Subjects:	Opiate Overdose--drug therapy Opiate Substitution Treatment Opioid-Related Disorders--drug therapy Tobacco Use Disorder--drug therapy Vaccines--pharmacokinetics
Publication Types:	Lecture Webcast

NLM Classification:	WM 284
NLM ID:	9918332582806676
CIT Live ID:	43773
Permanent link:	https://videocast.nih.gov/watch=43773

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