NIH VideoCast - Judith H. Greenberg Early Career Investigator Lecture - Looking for Lipids in All the Right Places: Host-Microbiome Interactions

Skip Navigation

Judith H. Greenberg Early Career Investigator Lecture - Looking for Lipids in All the Right Places: Host-Microbiome Interactions

Loading... Loading video...

415 Views

Air date:	Wednesday, September 29, 2021, 1:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 415 (210 Live, 205 On-demand)
Category:	Special
Runtime:	00:59:33
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Judith H. Greenberg Early Career Investigator Lecture Trillions of bacteria and other microorganisms that call your body home are collectively known as your microbiome. The exchange of compounds (mixtures of molecules) between your microbiome and your own cells allows good bacteria to thrive in your gut; it may also enable the microbiome to help protect the body against some diseases. By identifying important molecules transferred, researchers can provide new targets for medicines. However, determining the origins and roles of specific microbiome-derived compounds has been challenging. Sphingolipids are one group of molecules that influence host-microbiome interactions but aren’t thoroughly understood. They serve as signaling and structural molecules and are produced by humans, animals, plants, and a few bacterial species. Dr. Johnson’s research group has traced bacterial sphingolipids to newly observed locations in the body and found that these molecules affect host signaling pathways. Continuing the search for sphingolipids that influence host-microbe interactions could ultimately enable precise control over microbiome makeup and host health. For more information go to https://www.nigms.nih.gov/News/meetings/Pages/2021-nigms-directors-early-career-investigator-lecture.aspx

NLM Title:	Looking for lipids in all the right places : host-microbiome interactions / Elizabeth Johnson.
Author:	Johnson, Elizabeth. National Institute of General Medical Sciences (U.S.),
Publisher:
Abstract:	(CIT): Judith H. Greenberg Early Career Investigator Lecture Trillions of bacteria and other microorganisms that call your body home are collectively known as your microbiome. The exchange of compounds (mixtures of molecules) between your microbiome and your own cells allows good bacteria to thrive in your gut; it may also enable the microbiome to help protect the body against some diseases. By identifying important molecules transferred, researchers can provide new targets for medicines. However, determining the origins and roles of specific microbiome-derived compounds has been challenging. Sphingolipids are one group of molecules that influence host-microbiome interactions but aren't thoroughly understood. They serve as signaling and structural molecules and are produced by humans, animals, plants, and a few bacterial species. Dr. Johnson's research group has traced bacterial sphingolipids to newly observed locations in the body and found that these molecules affect host signaling pathways. Continuing the search for sphingolipids that influence host-microbe interactions could ultimately enable precise control over microbiome makeup and host health.
Subjects:	Gastrointestinal Microbiome Host Microbial Interactions Lipids
Publication Types:	Lecture Webcast

NLM Classification:	QW 41
NLM ID:	9918282190806676
CIT Live ID:	43771
Permanent link:	https://videocast.nih.gov/watch=43771

Related Videos...