TRP Ion Channels in the Nervous System

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Air date:	Monday, October 18, 2004, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 174 * This only includes stats from October 2011 and forward.
Category:	Neuroscience
Runtime:	00:57:21
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Neurotransmitters, hormones, and pharmacologic agents act by binding specific receptors on the cell surface. Dr. Clapham's lab is interested in how a receptor initiates intracellular events such as the opening of ion channels, the activation of enzymes, or the release of intracellular calcium; and the structures, functions, and relations of receptors, G proteins, ion channels, and calcium. The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to changes in their local environments. TRP channels are found in many eukaryotes, from yeast to mammals. They are a diverse group of proteins organized into six families. In the peripheral nervous system, stimuli including temperature, pressure, inflammatory agents, and receptor activation effect TRP-mediated responses. http://neuroseries.info.nih.gov

NLM Title:	TRP ion channels in the nervous system / David Clapham.
Author:	Clapham, David E. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Neurotransmitters, hormones, and pharmacologic agents act by binding specific receptors on the cell surface. Dr. Clapham's lab is interested in how a receptor initiates intracellular events such as the opening of ion channels, the activation of enzymes, or the release of intracellular calcium; and the structures, functions, and relations of receptors, G proteins, ion channels, and calcium. The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to changes in their local environments. TRP channels are found in many eukaryotes, from yeast to mammals. They are a diverse group of proteins organized into six families. In the peripheral nervous system, stimuli including temperature, pressure, inflammatory agents, and receptor activation effect TRP-mediated responses.
Subjects:	Peripheral Nervous System--metabolism Transient Receptor Potential Channels--physiology
Publication Types:	Lecture Webcast
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
NLM Classification:	QU 55.7
NLM ID:	101268575
CIT Live ID:	3545
Permanent link:	https://videocast.nih.gov/watch=3545

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