NIH VideoCast - Opioid receptors and brain function

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Opioid receptors and brain function

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Air date:	Wednesday, May 29, 2019, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 709 (204 Live, 505 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:01:27
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Director's Wednesday Afternoon Lecture Series Opiates have been in use for thousands of years for their remarkable pain-relieving and rewarding properties. Opiates produce their potent effects by activating opioid receptors in the brain, hijacking an endogenous opioid system, which is central to hedonic and mood homeostasis. Recently, revolutions in G-protein-coupled-receptor research, fascinating developments in basic neuroscience, and the rising opioid crisis have propelled opioid receptors back on stage. Dr. Kieffer's presentation will discuss rapidly evolving areas in opioid-receptor research for addiction including the key questions of whether we can use opiates to eliminate pain without addiction and how opioid receptors operate within the neurocircuitry of addiction. Dr. Kieffer will also present recent work describing how functional MRI is being used in mice to explore the link between the mu-opioid receptor gene and drug activities to whole-brain functional networks. For more information go to https://oir.nih.gov/wals/2018-2019

NLM Title:	Opioid receptors and brain function / Brigitte Kieffer.
Author:	Kieffer, Brigitte L. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): NIH Director's Wednesday Afternoon Lecture Series Opiates have been in use for thousands of years for their remarkable pain-relieving and rewarding properties. Opiates produce their potent effects by activating opioid receptors in the brain, hijacking an endogenous opioid system, which is central to hedonic and mood homeostasis. Recently, revolutions in G-protein-coupled-receptor research, fascinating developments in basic neuroscience, and the rising opioid crisis have propelled opioid receptors back on stage. Dr. Kieffer's presentation will discuss rapidly evolving areas in opioid-receptor research for addiction including the key questions of whether we can use opiates to eliminate pain without addiction and how opioid receptors operate within the neurocircuitry of addiction. Dr. Kieffer will also present recent work describing how functional MRI is being used in mice to explore the link between the mu-opioid receptor gene and drug activities to whole-brain functional networks.
Subjects:	Brain--drug effects Brain--physiology Opioid-Related Disorders--physiopathology Receptors, Opioid--drug effects Receptors, Opioid--physiology
Publication Types:	Lecture Webcast

NLM Classification:	QV 36
NLM ID:	101749146
CIT Live ID:	31987
Permanent link:	https://videocast.nih.gov/watch=31987

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