Story of My Roots: Disease Mutations of a Population

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Air date:	Wednesday, January 28, 2004, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 86 * This only includes stats from October 2011 and forward.
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	00:58:19
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Description:	The Human Genome Project has produced a high number of catalogued sequence variants enabling genome-wide studies of genetic loci behind disease-related phenotypes. The molecular defect has been identified in over 1500 monogenic diseases and first encouraging findings are reported for some common, polygenic traits. Population isolates like Finland have been very useful for mapping and cloning genes for rare disorders; in such isolates genetic drift leads to an overabundance of disease-alleles for particular disorders, and a high proportion of patients share these alleles, identical by descent. For more information, visit Leena at Department of Human Molecular Genetics and National Public Health Institute of Finland The NIH Director's Wednesday Afternoon Lecture Series

Author:	Leena Peltonen, M.D., Ph.D., National Public Health Institute of Finland
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
CIT Live ID:	2596
Permanent link:	https://videocast.nih.gov/watch=2596

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