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Interactions between Memory and Decision Systems of the Brain

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Air date: Monday, May 1, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 298 (45 Live, 253 On-demand)
Category: Neuroscience
Runtime: 01:10:01
Description: NIH Neuroscience Series Seminar

Understanding the mechanisms of neuroplasticity as related to learning and memory is fundamental to our understanding of the causes of a variety of cognitive disorders as well as the developmental changes in learning that occur across the lifespan. Dr. Mizumori’s laboratory attempts to address these issues by using a rodent model of spatial navigation to investigate the dynamic responses of single neurons in the brain, as well as the complex interactions between cells located in different memory-related structures. These studies employ techniques involving recording extracellular signals from many cells simultaneously as animals perform memory tasks. Their studies have examined many processes that contribute to successful and adaptive navigation: 1) the evaluation of sensory input during active locomotion, 2) the integration of current sensory information with past knowledge about an environment, and with internal state information, and 3) the behavioral implementation of highly processed spatial information. More recently, they have been considering these processes in terms of the flexibility of underlying neural representational systems during shifts in cognitive strategy or task demands. They are particularly interested in the role of neuromodulators such as dopamine in flexible memory function.

For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx
NLM Title: Interactions between memory and decision systems of the brain / Sheri J.Y. Mizumori.
Author: Mizumori, Sheri Jane.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Neuroscience Series Seminar Understanding the mechanisms of neuroplasticity as related to learning and memory is fundamental to our understanding of the causes of a variety of cognitive disorders as well as the developmental changes in learning that occur across the lifespan. Dr. Mizumori's laboratory attempts to address these issues by using a rodent model of spatial navigation to investigate the dynamic responses of single neurons in the brain, as well as the complex interactions between cells located in different memory-related structures. These studies employ techniques involving recording extracellular signals from many cells simultaneously as animals perform memory tasks. Their studies have examined many processes that contribute to successful and adaptive navigation: 1) the evaluation of sensory input during active locomotion, 2) the integration of current sensory information with past knowledge about an environment, and with internal state information, and 3) the behavioral implementation of highly processed spatial information. More recently, they have been considering these processes in terms of the flexibility of underlying neural representational systems during shifts in cognitive strategy or task demands. They are particularly interested in the role of neuromodulators such as dopamine in flexible memory function.
Subjects: Cognition Disorders--etiology
Memory--physiology
Neuronal Plasticity--physiology
Publication Types: Lecture
Webcast
 
NLM Classification: WL 337
NLM ID: 101706982
CIT Live ID: 20266
Permanent link: https://videocast.nih.gov/watch=20266

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