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Myelin, movement and motor skills learning

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Air date: Monday, October 31, 2016, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 236 (24 Live, 212 On-demand)
Category: Neuroscience
Runtime: 01:06:38
Description: NIH Neuroscience Seminar Series

Oligodendrocyte precursors (OPs or NG2 glia) are ~5% of all neural cells in the brain and spinal cord and they continue to generate myelin-forming oligodendrocytes throughout young adult life. Dr. Richardson’s lab has shown recently that oligodendrocyte production is accelerated in adult mice within a few hours of their starting to practice a complex motor task, and that these newly-forming cells are required for learning. Dr. Richardson will present these data and discuss the role of new myelin in circuit selection and refinement during learning. He will also describe their unpublished work on AMPA receptor signaling in OPs and its role in controlling development of oligodendrocytes and myelin.

For more information go to https://neuroscience.nih.gov/neuroseries/Home
NLM Title: Myelin, movement, and motor skills learning / William Richardson.
Author: Richardson, William D.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Oligodendrocyte precursors (OPs or NG2 glia) are ~5% of all neural cells in the brain and spinal cord and they continue to generate myelin-forming oligodendrocytes throughout young adult life. Dr. Richardson's lab has shown recently that oligodendrocyte production is accelerated in adult mice within a few hours of their starting to practice a complex motor task, and that these newly-forming cells are required for learning. Dr. Richardson will present these data and discuss the role of new myelin in circuit selection and refinement during learning. He will also describe their unpublished work on AMPA receptor signaling in OPs and its role in controlling development of oligodendrocytes and myelin.
Subjects: Learning
Motor Activity--physiology
Motor Skills--physiology
Myelin Basic Protein--metabolism
Myelin Sheath--physiology
Publication Types: Lecture
Webcast
 
NLM Classification: WL 102.5
NLM ID: 101697704
CIT Live ID: 19777
Permanent link: https://videocast.nih.gov/watch=19777

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