NIH VideoCast - Dissecting the Neural Circuits that Mediate Motivated Behavior

Skip Navigation

Dissecting the Neural Circuits that Mediate Motivated Behavior

Loading... Loading video...

375 Views

Air date:	Monday, September 19, 2016, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 375 (49 Live, 326 On-demand)
Category:	Neuroscience
Runtime:	01:12:57
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Neuroscience Seminar Series Dr. Stuber lab's primary research goal is to further delineate the synaptic mechanisms and functional neural circuitry that underlie motivated behavioral processes that are perturbed in neuropsychiatric disorders such as addiction, depression, and eating disorders. Throughout his graduate and postdoctoral training, he utilized both in vivo and in vitro methodologies to study rapid dopamine signaling as well as synaptic plasticity during or immediately following behavior. His lab's current research focuses on the synaptic and neural circuit mechanisms that underlie adaptive and maladaptive behavioral states. To accomplish this, they employ multiple cutting-edge techniques both in vivo and in vitro. Specifically, they use in vivo fast-scan cyclic voltammetry to monitor the release of dopamine, in vivo electrophysiology to monitor neural activity during behavior, and ex vivo patch-clamp electrophysiology to measure additional synaptic alterations following learning. These experimental approaches also incorporate optogenetic stimulation or inhibition in vitro and in vivo to allow for pathway-specific perturbation of neural function. Collectively, his lab aims to generate a holistic understanding of neural circuit function that underlies complex motivated behavioral processing, with the long term of goal of identifying novel neural circuit elements to therapeutically target for the treatment of neuropsychiatric illnesses. For more information go to https://neuroscience.nih.gov/neuroseries/Home

NLM Title:	Dissecting the neural circuits that mediate motivated behavior / Garret Stuber.
Author:	Stuber, Garret. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): NIH Neuroscience Seminar Series Dr. Stuber lab's primary research goal is to further delineate the synaptic mechanisms and functional neural circuitry that underlie motivated behavioral processes that are perturbed in neuropsychiatric disorders such as addiction, depression, and eating disorders. Throughout his graduate and postdoctoral training, he utilized both in vivo and in vitro methodologies to study rapid dopamine signaling as well as synaptic plasticity during or immediately following behavior. His lab's current research focuses on the synaptic and neural circuit mechanisms that underlie adaptive and maladaptive behavioral states. To accomplish this, they employ multiple cutting-edge techniques both in vivo and in vitro. Specifically, they use in vivo fast-scan cyclic voltammetry to monitor the release of dopamine, in vivo electrophysiology to monitor neural activity during behavior, and ex vivo patch-clamp electrophysiology to measure additional synaptic alterations following learning. These experimental approaches also incorporate optogenetic stimulation or inhibition in vitro and in vivo to allow for pathway-specific perturbation of neural function. Collectively, his lab aims to generate a holistic understanding of neural circuit function that underlies complex motivated behavioral processing, with the long term of goal of identifying novel neural circuit elements to therapeutically target for the treatment of neuropsychiatric illnesses.
Subjects:	Behavior, Animal Brain--physiology Hormones--physiology Motivation--physiology Neural Pathways--physiology Neurons--physiology
Publication Types:	Lecture Webcast

NLM Classification:	WL 102
NLM ID:	101693826
CIT Live ID:	19699
Permanent link:	https://videocast.nih.gov/watch=19699

Related Videos...