An Ecological Role for Pseudomonas Virulence Factors

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Air date:	Wednesday, December 11, 2002, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 104 * This only includes stats from October 2011 and forward.
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:06:00
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	The NIH Director's Wednesday Afternoon Lecture Series Pathogenic bacteria are most often studied in the context of the disease they cause on their human host. Yet, many such pathogens spend much of their existence in environments outside the host. Are there ecological roles for some virulence factors? What genomic sequences are selected for in the environment? As an initial approach to answer these questions our laboratory is carrying out experiments on fungal-bacterial interactions, focussing on the bacterium Pseudomonas aeruginosa. These experiments, along with comparative genomic studies, have revealed that widely conserved genes that encode mammalian virulence factors are involved in antogonistic interactions with microbial eukaryotes. For more information, visit http://gasp.med.harvard.edu

Author:	Roberto G. Kolter, Ph.D., Harvard Medical School
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
CIT Live ID:	1875
Permanent link:	https://videocast.nih.gov/watch=1875

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