NIH VideoCast - An Unexpected Role for DNA Damage Response Kinases in Antigen Receptor Signaling.

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An Unexpected Role for DNA Damage Response Kinases in Antigen Receptor Signaling.

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Air date:	Wednesday, February 3, 2016, 4:15:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 314 (53 Live, 261 On-demand)
Category:	Immunology
Runtime:	00:49:37
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Carrie Lucas is a Postdoctoral Fellow in Mike Lenardo’s lab in NIAID who will transition soon to an Assistant Professor position in Immunobiology at Yale University School of Medicine. Carrie received her PhD from Harvard Medical School, where she studied CD8 T cell tolerance in mouse models of allogeneic bone marrow transplantation. As a postdoc, she has studied signal transduction in human lymphocytes with a particular focus on phosphoinositide 3-kinase (PI3K) signaling in patients with inherited mutations in PI3K subunits. Some of her recent awards include the AAI-Life Technologies Trainee Achievement Award, the Keystone Symposia Future of Science Award, and the K99/R00 Pathway to Independence Grant. Outside of science, her daughter and husband fill her personal time with all sorts of adventures, including hiking, skiing, and running. In this seminar, Carrie will present her journey from studies in PI3K patients to her more recent discovery of a critical role for a PI3K-like kinase and its downstream DNA damage response effector kinase in antigen receptor signaling.

NLM Title:	An unexpected role for DNA damage response kinases in antigen receptor signaling / Carrie L. Lucas ; Immunology Interest Group.
Author:	Lucas, Carrie L. National Institutes of Health (U.S.). Immunology Interest Group,
Publisher:
Abstract:	(CIT): Carrie Lucas is a Postdoctoral Fellow in Mike Lenardo's lab in NIAID who will transition soon to an Assistant Professor position in Immunobiology at Yale University School of Medicine. Carrie received her PhD from Harvard Medical School, where she studied CD8 T cell tolerance in mouse models of allogeneic bone marrow transplantation. As a postdoc, she has studied signal transduction in human lymphocytes with a particular focus on phosphoinositide 3-kinase (PI3K) signaling in patients with inherited mutations in PI3K subunits. Some of her recent awards include the AAI-Life Technologies Trainee Achievement Award, the Keystone Symposia Future of Science Award, and the K99/R00 Pathway to Independence Grant. Outside of science, her daughter and husband fill her personal time with all sorts of adventures, including hiking, skiing, and running. In this seminar, Carrie will present her journey from studies in PI3K patients to her more recent discovery of a critical role for a PI3K-like kinase and its downstream DNA damage response effector kinase in antigen receptor signaling.
Subjects:	DNA Damage Phosphatidylinositol 3-Kinases Receptors, Antigen
Publication Types:	Lecture Webcast

NLM Classification:	QU 141
NLM ID:	101678402
CIT Live ID:	18346
Permanent link:	https://videocast.nih.gov/watch=18346

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