NIH VideoCast - Molecular mechanisms of neuronal polarization

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Molecular mechanisms of neuronal polarization

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Air date:	Monday, February 23, 2015, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 321 (42 Live, 279 On-demand)
Category:	Neuroscience
Runtime:	01:09:30
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Neuroscience Seminar Series Shen’s laboratory is interested in understanding the molecular mechanisms of neural circuit assembly. They are studying a number of key cell biological questions during the development and maintenance of neural circuits. Although they have traditionally focused on mechanisms of synaptic specificity and synapse assembly, their recent work has also started to shed light on the mechanisms of axonal transport, neuronal cytoskeletal polarity, and dendrite branching. 1. Axon guidance cues can pattern synapses by inhibiting synaptogenesis and maintenance. 2. Cellular and molecular mechanisms of synaptic specificity in vivo. 3. Molecular mechanisms of presynaptic assembly in vivo. 4. Interaction of active zone proteins and synaptic vesicles (SV) dictate the trafficking of SV and the size of synapses. 5. Molecular regulation of the intracellular trafficking of synaptic vesicles. 6. Molecular mechanisms of microtubule polarity in neurons. 7. Molecular mechanisms of dendrite branching and growth.

NLM Title:	Molecular mechanisms of neuronal polarization / Kang Shen.
Author:	Shen, Kang. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): Shen's laboratory is interested in understanding the molecular mechanisms of neural circuit assembly. They are studying a number of key cell biological questions during the development and maintenance of neural circuits. Although they have traditionally focused on mechanisms of synaptic specificity and synapse assembly, their recent work has also started to shed light on the mechanisms of axonal transport, neuronal cytoskeletal polarity, and dendrite branching. 1. Axon guidance cues can pattern synapses by inhibiting synaptogenesis and maintenance. 2. Cellular and molecular mechanisms of synaptic specificity in vivo. 3. Molecular mechanisms of presynaptic assembly in vivo. 4. Interaction of active zone proteins and synaptic vesicles (SV) dictate the trafficking of SV and the size of synapses. 5. Molecular regulation of the intracellular trafficking of synaptic vesicles. 6. Molecular mechanisms of microtubule polarity in neurons. 7. Molecular mechanisms of dendrite branching and growth.
Subjects:	Neurons--physiology
Publication Types:	Lecture Webcast

NLM Classification:	WL 102.5
NLM ID:	101654012
CIT Live ID:	15068
Permanent link:	https://videocast.nih.gov/watch=15068

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