NIH VideoCast - Redox Biology 2014 - Cancer Therapy, Redox Enzymology

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Redox Biology 2014 - Cancer Therapy, Redox Enzymology

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Air date:	Tuesday, October 21, 2014, 4:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 157 (12 Live, 145 On-demand)
Category:	Redox Biology
Runtime:	01:46:50
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Redox Biology Recent advances in the biochemistry of redox-active species and radicals are beginning to be translated into improvements in prevention and treatment of cancer. Traditionally, reactive species such as superoxide, hydrogen peroxide and nitric oxide (NO) are associated with toxicity; however, NO is useful in the treatment of angina and cardiovascular disease. Also, NO is involved in cancer tumor angiogenesis and apoptosis of cancer cells. This course is an overview presenting how redox-active species and radicals are generated; their effects on the cellular and physiological level, how they alter carcinogenesis, angiogenesis and proliferation in animal models of cancer, and how NO alters patient imaging profiles and response to cancer therapy. It consists of two 1-hour lectures with ample time for discussion and analysis. The participation of postdoctoral and clinical fellows interested in redox biology is encouraged. For more information go to http://ccr.cancer.gov/careers/courses/rb

NLM Title:	Redox biology 2014. Cancer therapy. Redox enzymology / Jim Mitchell, L. Ridnour.
Author:	Mitchell, James B. Ridnour, L. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Redox Biology Recent advances in the biochemistry of redox-active species and radicals are beginning to be translated into improvements in prevention and treatment of cancer. Traditionally, reactive species such as superoxide, hydrogen peroxide and nitric oxide (NO) are associated with toxicity; however, NO is useful in the treatment of angina and cardiovascular disease. Also, NO is involved in cancer tumor angiogenesis and apoptosis of cancer cells. This course is an overview presenting how redox-active species and radicals are generated; their effects on the cellular and physiological level, how they alter carcinogenesis, angiogenesis and proliferation in animal models of cancer, and how NO alters patient imaging profiles and response to cancer therapy. It consists of two 1-hour lectures with ample time for discussion and analysis. The participation of postdoctoral and clinical fellows interested in redox biology is encouraged.
Subjects:	Breast Neoplasms--enzymology Inflammation Neoplasm Metastasis Neoplasms--radiotherapy Oxidation-Reduction
Publication Types:	Lecture Webcast

NLM Classification:	QZ 269
NLM ID:	101645903
CIT Live ID:	14608
Permanent link:	https://videocast.nih.gov/watch=14608

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