NIH VideoCast - Optogenetics: Development and Application

Skip Navigation

Optogenetics: Development and Application

Loading... Loading video...

968 Views

Air date:	Monday, February 13, 2012, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 968 (101 Live, 867 On-demand)
Category:	Neuroscience
Runtime:	01:05:19
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Neuroscience Seminar Series Dr. Deisseroth's lab has developed and applied optogenetic methods based on microbial opsin genes, to achieve gain- or loss-of-function of well-defined events within specific cells of living tissue, including freely moving mammals. This talk will cover their recent efforts on optogenetics, including the crystal structure of channelrhodopsin, recent genomic and molecular engineering work to expand the microbial opsin toolkit, the development of novel optogenetic hardware and techniques (based on optical imaging, ofMRI, electrophysiology, and behavior) for control and readout of neural activity, and a number of optogenetic applications relevant to neuropsychiatric disease, spanning anxiety, social behavior dysfunction, fear memory recall, drug abuse, and depression. For more information, visit: http://neuroseries.info.nih.gov

NLM Title:	Optogenetics : development and application / Karl Deisseroth.
Author:	Deisseroth, Karl. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Dr. Deisseroth's lab has developed and applied optogenetic methods based on microbial opsin genes, to achieve gain- or loss-of-function of well-defined events within specific cells of living tissue, including freely moving mammals. This talk will cover their recent efforts on optogenetics, including the crystal structure of channelrhodopsin, recent genomic and molecular engineering work to expand the microbial opsin toolkit, the development of novel optogenetic hardware and techniques (based on optical imaging, of MRI, electrophysiology, and behavior) for control and readout of neural activity, and a number of optogenetic applications relevant to neuropsychiatric disease, spanning anxiety, social behavior dysfunction, fear memory recall, drug abuse, and depression.
Subjects:	Fiber Optic Technology Nerve Tissue Proteins--physiology Neural Pathways--physiology Opsins--genetics Prefrontal Cortex--physiology Rhodopsin--genetics
Publication Types:	Lecture Webcast
NLM Classification:	WL 307
NLM ID:	101581445
CIT Live ID:	10766
Permanent link:	https://videocast.nih.gov/watch=10766

Related Videos...