Dr. Adi Gazdar was born in Bombay, India. After obtaining his medical training at Guys Hospital, University of London, he did a residency in pathology at Harvard Medical School, Boston. For several years he worked as a Medical Investigator at the NCI-Navy Medical Oncology Branch, National Cancer Institute, Maryland. In 1991 he joined the University of Texas Southwestern Medical Center, Dallas, where he has an endowed chair in the Department of Pathology and serves as Deputy Head of the Hamon Center for Therapeutic Oncology Research. He is the recipient of the Mary Matthews award from the International Association for the Study of Lung Cancer and the Jacqueline Seroussi Foundation for his contributions to lung cancer research.

Dr. Gazdar’s research interests center on understanding the multistage pathogenesis of human malignancies, with a special interest in lung and breast cancers. He has published nearly 650 medical articles, including more than 300 in the field of lung cancer. The Institute for Scientific Information includes Dr. Gazdar in a list of the world's most cited authors--comprising less than one half of one percent of all publishing researchers, based on the important scientific developments of the last two decades. He serves as an Associate Editor for several journals including Cancer Research, International Journal of Cancer and Clinical Cancer Research. His major interests include the role of methylation as a mechanism of silencing of tumor suppressor genes, markers for early diagnosis and risk assessment and deregulation of the Epidermal Growth Factor Gene signaling pathway in the pathogenesis of lung and other cancers. He serves as the Principal Investigator of a newly launched multiplatform, multi-institutional approach to study lung cancer in never smokers, funded jointly by the National Cancer Institute and the Canary Foundation.

SELECTED REFERENCES:
1. Subramanian J, Govindan R. Molecular genetics of lung cancer in people who have never smoked. The Lancet Oncology 2008; 9:676–82.
2. Sun S, Schiller JH, Gazdar AF. Lung cancer in never smokers - a different disease. Nature Reviews 2007; 7: 778–90. Yano T, Miura N, Takenaka T, Haro A, Okazaki H, Ohba T, Kouso H, Kometani T, Shoji F, Maehara Y. Never-smoking nonsmall cell lung cancer as a separate entity: clinicopathologic features and survival. Cancer 2008; 113: 1012–8.

NCI’s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx