1c:{"metadata":[["$","title","0",{"children":"NIH VideoCast - To Kill or To Cure: Options in Host Defense Against Viral Infections"}],["$","meta","1",{"name":"description","content":"The end result of a successful host response to viral infection is thought to be production of neutralizing antibodies and the destruction of infected cells. In this presentation I will use the hepatitis B and C viruses as model systems to describe our studies that identified a third antiviral effector function of the immune response, i.e. the secretion of antiviral cytokines that can purge viruses from infected cells without killing them. I will also discuss our knowledge of the intracellular signaling cascades and intracellular antiviral mechanisms that mediate these effects, the structural and nonstructural elements within candidate viruses that are targeted by these cytokines, and the ability of these mechanisms to prevent viral spread and cure infected cells.\n
\n
\nFor more information, visit
\nhttp://www.scripps.edu/mem/expath/chisari\n
\n
\nWALS\n
"}],["$","meta","2",{"name":"publisher","content":"National Institutes of Health"}],["$","meta","3",{"property":"og:title","content":"NIH VideoCast - To Kill or To Cure: Options in Host Defense Against Viral Infections"}],["$","meta","4",{"property":"og:description","content":"The end result of a successful host response to viral infection is thought to be production of neutralizing antibodies and the destruction of infected cells. In this presentation I will use the hepatitis B and C viruses as model systems to describe our studies that identified a third antiviral effector function of the immune response, i.e. the secretion of antiviral cytokines that can purge viruses from infected cells without killing them. I will also discuss our knowledge of the intracellular signaling cascades and intracellular antiviral mechanisms that mediate these effects, the structural and nonstructural elements within candidate viruses that are targeted by these cytokines, and the ability of these mechanisms to prevent viral spread and cure infected cells.\n
\n
\nFor more information, visit
\nhttp://www.scripps.edu/mem/expath/chisari\n
\n
\nWALS\n
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\n
\nFor more information, visit
\nhttp://www.scripps.edu/mem/expath/chisari\n
\n
\nWALS\n
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