1c:{"metadata":[["$","title","0",{"children":"NIH VideoCast - Functional Proteomics: Methods Development and Applications to Signal Transduction"}],["$","meta","1",{"name":"description","content":"Functional proteomics provides a powerful approach to screen for molecular responses at the protein level. By combining 2D gels and mass spectrometry with standard molecular pharmacological strategies, responses to specific signal transduction pathways can be monitored. The results reveal novel targets for regulation by post-translational modification,\nwhich compliment information from gene array analyses. Applications to\nMAP kinase and Rho GTPase pathways will be presented. 2D-gel based\napproaches also reveal proteins that are differentially expressed between melanocyte vs melanoma cultured cell lines.

\nFor more information, visit
\nNatalie Ahn\n

\nNIH Director's Wednesday Afternoon Lecture Series.\n
"}],["$","meta","2",{"name":"publisher","content":"National Institutes of Health"}],["$","meta","3",{"property":"og:title","content":"NIH VideoCast - Functional Proteomics: Methods Development and Applications to Signal Transduction"}],["$","meta","4",{"property":"og:description","content":"Functional proteomics provides a powerful approach to screen for molecular responses at the protein level. By combining 2D gels and mass spectrometry with standard molecular pharmacological strategies, responses to specific signal transduction pathways can be monitored. The results reveal novel targets for regulation by post-translational modification,\nwhich compliment information from gene array analyses. Applications to\nMAP kinase and Rho GTPase pathways will be presented. 2D-gel based\napproaches also reveal proteins that are differentially expressed between melanocyte vs melanoma cultured cell lines.

\nFor more information, visit
\nNatalie Ahn\n

\nNIH Director's Wednesday Afternoon Lecture Series.\n
"}],["$","meta","5",{"property":"og:url","content":"https://uat.d1rkikwu4q8tg.amplifyapp.com/watch/97c77ddc-d5db-11f0-9cf9-12c45c580ad9"}],["$","meta","6",{"property":"og:site_name","content":"NIH VideoCast"}],["$","meta","7",{"property":"og:image","content":"https://nihcit.rev.vbrick.com/api/v2/media/videos/thumbnails/77f29925-4d1b-42c6-9a88-11acff5fc908.jpg"}],["$","meta","8",{"property":"og:type","content":"website"}],["$","meta","9",{"name":"twitter:card","content":"summary_large_image"}],["$","meta","10",{"name":"twitter:title","content":"NIH VideoCast - Functional Proteomics: Methods Development and Applications to Signal Transduction"}],["$","meta","11",{"name":"twitter:description","content":"Functional proteomics provides a powerful approach to screen for molecular responses at the protein level. By combining 2D gels and mass spectrometry with standard molecular pharmacological strategies, responses to specific signal transduction pathways can be monitored. The results reveal novel targets for regulation by post-translational modification,\nwhich compliment information from gene array analyses. Applications to\nMAP kinase and Rho GTPase pathways will be presented. 2D-gel based\napproaches also reveal proteins that are differentially expressed between melanocyte vs melanoma cultured cell lines.

\nFor more information, visit
\nNatalie Ahn\n

\nNIH Director's Wednesday Afternoon Lecture Series.\n
"}],"$L22","$L23","$L24"],"error":null,"digest":"$undefined"}