1 00:00:13,825 --> 00:00:15,227 I AS WELL AS ON BEHALF OF FELLOW 2 00:00:15,227 --> 00:00:16,295 NIH STAFF WOULD LIKE TO WELCOME 3 00:00:16,295 --> 00:00:18,030 ALL OF YOU TO THE OPEN SESSION 4 00:00:18,030 --> 00:00:19,564 OF THE EMOTIONAL WELL-BEING HIGH 5 00:00:19,564 --> 00:00:21,133 PRIORITY RESEARCH NETWORK'S 6 00:00:21,133 --> 00:00:23,268 ANNUAL INVESTIGATORS MEETING. 7 00:00:23,268 --> 00:00:24,603 BRIEFLY, TO THOSE OF YOU JOINING 8 00:00:24,603 --> 00:00:28,106 US BY NIH VIDEOCAST, YOU MAY 9 00:00:28,106 --> 00:00:32,110 POST A QUESTION USING THE 10 00:00:32,110 --> 00:00:32,878 VIDEOCAST FORM AT ANY TIME AND 11 00:00:32,878 --> 00:00:34,913 WE WILL ASK QUESTIONS DURING THE 12 00:00:34,913 --> 00:00:36,748 TWO Q & A SESSIONS THIS MORNING. 13 00:00:36,748 --> 00:00:38,116 FOR THE SMALL AMOUNT JOINING BY 14 00:00:38,116 --> 00:00:39,918 ZOOM, IF YOU COULD PLEASE MUTE 15 00:00:39,918 --> 00:00:41,119 YOURSELF UNLESS SPEAKING, RAISE 16 00:00:41,119 --> 00:00:42,954 YOUR DIGITAL HAND AND WAIT UNTIL 17 00:00:42,954 --> 00:00:44,790 YOU'RE CALLED AND KEEP YOUR 18 00:00:44,790 --> 00:00:47,259 VIDEO ON WHILE YOU ARE SPEAKING. 19 00:00:47,259 --> 00:00:48,226 WE ARE █FORTUNATE TO BEGIN THIS 20 00:00:48,226 --> 00:00:50,529 MORNING WITH WELCOME REMARKS 21 00:00:50,529 --> 00:00:52,798 FROM TWO DIRECTORS FROM NIH 22 00:00:52,798 --> 00:00:54,466 INSTITUTES AND CENTERS THAT HAVE 23 00:00:54,466 --> 00:00:56,535 SUPPORTED THE EMOTIONAL 24 00:00:56,535 --> 00:00:58,270 WELL-BEING NETWORKS, DR. HELENE 25 00:00:58,270 --> 00:00:59,338 LANGEVIN, DIRECTOR OF THE 26 00:00:59,338 --> 00:01:01,373 NATIONAL CENTER FOR 27 00:01:01,373 --> 00:01:02,007 COMPLEMENTARY INNOVATIVE HEALTH 28 00:01:02,007 --> 00:01:04,509 AND DR. AMY KELLEY, DIRECTOR OF 29 00:01:04,509 --> 00:01:06,545 THE NATIONAL INSTITUTE ON AGING. 30 00:01:06,545 --> 00:01:07,779 UNFORTUNATELY DR. ALISON 31 00:01:07,779 --> 00:01:10,649 CERNICH, DEPUTY DIRECTOR COULD 32 00:01:10,649 --> 00:01:11,750 NOT MAKE IT AT THE LAST MINUTE 33 00:01:11,750 --> 00:01:13,352 THIS MORNING BUT DR. TRACY KING 34 00:01:13,352 --> 00:01:15,020 WILL BE PROVIDING REMARKS ON HER 35 00:01:15,020 --> 00:01:15,987 BEHALF. 36 00:01:15,987 --> 00:01:17,222 SO FIRST, I'D LIKE TO INTRODUCE 37 00:01:17,222 --> 00:01:18,090 DR. HELENE LANGEVIN TO GIVE HER 38 00:01:18,090 --> 00:01:24,663 OPENING REMARKS. 39 00:01:24,663 --> 00:01:28,500 >> THANK YOU SO MEC MUCH, ERIN D 40 00:01:28,500 --> 00:01:30,902 THE WHOLE VILLAGE THAT SORT OF 41 00:01:30,902 --> 00:01:32,204 CONTRIBUTED TO MAKING THIS 42 00:01:32,204 --> 00:01:33,739 MEETING IN PERSON HAPPEN, SO 43 00:01:33,739 --> 00:01:35,273 NICE TO SEE SO MANY OF YOU. 44 00:01:35,273 --> 00:01:39,511 AND TO ALL OF YOU THAT GOES ON 45 00:01:39,511 --> 00:01:40,312 ZOOM AS WELL. 46 00:01:40,312 --> 00:01:42,247 IT'S MY GREAT PLEASURE TO 47 00:01:42,247 --> 00:01:44,983 WELCOME YOU TO THIS INVESTIGATOR 48 00:01:44,983 --> 00:01:46,785 MEETING OF THE EMOTIONAL 49 00:01:46,785 --> 00:01:47,452 WELL-BEING NETWORKS. 50 00:01:47,452 --> 00:01:50,288 IT'S BEEN REALLY SO EXCITING 51 00:01:50,288 --> 00:01:54,659 OVER THE LAST YEARS TO SEE ALL 52 00:01:54,659 --> 00:01:56,395 THE RESEARCH THAT'S GENERATED BY 53 00:01:56,395 --> 00:01:59,364 THESE SIX NETWORKS. 54 00:01:59,364 --> 00:02:02,267 INCLUDING ONTOLOGY, METHODOLOGY, 55 00:02:02,267 --> 00:02:04,236 MECHANISMS, BIOMARKERS, 56 00:02:04,236 --> 00:02:06,104 TECHNOLOGY, AND AS WELL AS 57 00:02:06,104 --> 00:02:08,373 IMPORTANTLY THE DEVELOPMENT AND 58 00:02:08,373 --> 00:02:10,275 VALIDATION OF THESE WELL-BEING 59 00:02:10,275 --> 00:02:12,110 MEASURES. 60 00:02:12,110 --> 00:02:15,747 DEVELOPING HOW TO EXACTLY DEFINE 61 00:02:15,747 --> 00:02:17,849 AND MEASURE EMOTIONAL 62 00:02:17,849 --> 00:02:18,984 WELL-BEING, IT'S MORE RELEVANT 63 00:02:18,984 --> 00:02:21,453 THAN EVER. 64 00:02:21,453 --> 00:02:24,256 WHEN THESE NETWORKS STARTED 65 00:02:24,256 --> 00:02:25,257 SEVERAL YEARS AGO, WE HAD A 66 00:02:25,257 --> 00:02:26,358 SENSE THIS WAS SOMETHING THAT 67 00:02:26,358 --> 00:02:27,659 REALLY NEEDED TO HAPPEN, AND THE 68 00:02:27,659 --> 00:02:29,394 MORE THE TIME PASSES, AND AS I 69 00:02:29,394 --> 00:02:30,729 WILL SHOW YOU IN A MINUTE, I 70 00:02:30,729 --> 00:02:33,532 MEAN, THIS IS NOW, YOU KNOW, 71 00:02:33,532 --> 00:02:34,766 WELL-BEING HAS BECOME PART OF 72 00:02:34,766 --> 00:02:36,868 THE CONVERSATION IN SO MANY 73 00:02:36,868 --> 00:02:37,269 PLACES. 74 00:02:37,269 --> 00:02:39,504 SO THE WORK OF THIS GROUP IS 75 00:02:39,504 --> 00:02:44,543 ABSOLUTELY KEY. 76 00:02:44,543 --> 00:02:45,677 I'M GOING TO TALK A LITTLE BIT 77 00:02:45,677 --> 00:02:47,245 ABOUT THE IMPORTANCE OF 78 00:02:47,245 --> 00:02:47,913 EMOTIONAL WELL-BEING IN THE 79 00:02:47,913 --> 00:02:48,914 CONTEXT OF WELL-BEING IN 80 00:02:48,914 --> 00:02:53,952 GENERAL, AND ALSO OF HEALTH. 81 00:02:53,952 --> 00:03:00,392 IN FACT, THE WORDS HEALTH AND 82 00:03:00,392 --> 00:03:02,828 WELL-BEING ARE SO OFTEN 83 00:03:02,828 --> 00:03:04,062 PRONOUNCED TOGETHER. 84 00:03:04,062 --> 00:03:05,163 IT'S ALMOST LIKE THEY'VE BECOME 85 00:03:05,163 --> 00:03:05,764 ONE WORD. 86 00:03:05,764 --> 00:03:07,165 AND THEY'RE SO OFTEN MENTIONED 87 00:03:07,165 --> 00:03:10,001 IN THE SAME BREATH, IN 88 00:03:10,001 --> 00:03:12,304 DISCUSSIONS ABOUT GOALS FOR 89 00:03:12,304 --> 00:03:14,272 PUBLIC HEALTH, FOR HEALTHCARE 90 00:03:14,272 --> 00:03:16,241 PROGRAMS, ET CETERA, THAT -- BUT 91 00:03:16,241 --> 00:03:18,877 THERE REMAINS A LOT OF QUESTIONS 92 00:03:18,877 --> 00:03:23,148 ABOUT HOW IS HEALTH RELATED TO 93 00:03:23,148 --> 00:03:23,448 WELL-BEING? 94 00:03:23,448 --> 00:03:25,450 AND HOW IS WELL-BEING RELATED TO 95 00:03:25,450 --> 00:03:28,553 HEALTH? 96 00:03:28,553 --> 00:03:29,955 IS WELL-BEING PART OF HEALTH OR 97 00:03:29,955 --> 00:03:31,223 IS HEALTH PART OF WELL-BEING OR 98 00:03:31,223 --> 00:03:33,859 ARE THEY PART OF EACH OTHER 99 00:03:33,859 --> 00:03:35,794 SOMEHOW? 100 00:03:35,794 --> 00:03:37,028 SO IF YOU DON'T MIND BEARING 101 00:03:37,028 --> 00:03:39,030 WITH ME FOR A FEW MINUTES, I 102 00:03:39,030 --> 00:03:40,198 WANT TO POSE A FEW QUESTIONS FOR 103 00:03:40,198 --> 00:03:42,133 US TO PONDER OVER, AND I'D LIKE 104 00:03:42,133 --> 00:03:44,102 TO REALLY -- FOR US TO THINK 105 00:03:44,102 --> 00:03:46,771 ABOUT THAT IN THE CONTEXT OF OUR 106 00:03:46,771 --> 00:03:51,676 DISCUSSIONS TODAY. 107 00:03:51,676 --> 00:03:52,644 SO FOR EXAMPLE, I'M GOING TO 108 00:03:52,644 --> 00:03:53,945 GIVE YOU A COUPLE EXAMPLES THAT 109 00:03:53,945 --> 00:03:56,114 I THINK ARE A LITTLE BIT 110 00:03:56,114 --> 00:03:56,581 PROVOCATIVE. 111 00:03:56,581 --> 00:03:57,816 ONE, THERE'S A BIG INITIATIVE 112 00:03:57,816 --> 00:04:00,585 GOING ON AT THE V.A. NOW THAT'S 113 00:04:00,585 --> 00:04:02,587 VERY, VERY KIND OF ENTRENCHED 114 00:04:02,587 --> 00:04:04,489 AND IT IS THEIR WHOLE HEALTH 115 00:04:04,489 --> 00:04:07,425 PROGRAM, AND THE WHOLE HEALTH 116 00:04:07,425 --> 00:04:10,028 PROGRAM IS BASED ON VERY 117 00:04:10,028 --> 00:04:11,830 IMPORTANT QUESTIONS INSTEAD OF 118 00:04:11,830 --> 00:04:13,598 SAYING WHAT'S THE MATTER WITH 119 00:04:13,598 --> 00:04:15,967 YOU, IT'S SAYING, WHAT MATTERS 120 00:04:15,967 --> 00:04:17,702 TO YOU. 121 00:04:17,702 --> 00:04:19,304 AND WELL-BEING IS AT THE CENTER 122 00:04:19,304 --> 00:04:22,741 OF THIS PROGRAM. 123 00:04:22,741 --> 00:04:25,310 AND SO THE WAY THAT WELL-BEING 124 00:04:25,310 --> 00:04:30,515 IS BEING DEFINED AT THE V.A. IS 125 00:04:30,515 --> 00:04:31,283 INTO FIVE DOMAINS. 126 00:04:31,283 --> 00:04:34,452 YOU CAN SEE THERE'S SOCIAL, 127 00:04:34,452 --> 00:04:36,187 ENVIRONMENTAL, HEALTH, ECONOMIC, 128 00:04:36,187 --> 00:04:37,389 AND VOCATIONAL-EDUCATIONAL. 129 00:04:37,389 --> 00:04:39,424 YOU CAN SEE HERE THAT IN THIS 130 00:04:39,424 --> 00:04:43,962 PARTICULAR CONSTRUCT, HEALTH IS 131 00:04:43,962 --> 00:04:46,531 AN -- AND EMOTIONAL HEALTH IS 132 00:04:46,531 --> 00:04:47,365 PART OF WELL-BEING. 133 00:04:47,365 --> 00:04:50,268 HERE'S ANOTHER EXAMPLE. 134 00:04:50,268 --> 00:04:52,804 THE WORLD HEALTH ORGANIZATION, 135 00:04:52,804 --> 00:04:54,272 LONG-STANDING VERY USED 136 00:04:54,272 --> 00:04:54,573 DEFINITION. 137 00:04:54,573 --> 00:04:56,408 HOW IS HEALTH DEFINED? 138 00:04:56,408 --> 00:04:58,476 A STATE OF COMPLETE PHYSICAL, 139 00:04:58,476 --> 00:05:01,112 MENTAL AND SOCIAL WELL-BEING, 140 00:05:01,112 --> 00:05:02,747 AND NOT MERELY THE ABSENCE OF 141 00:05:02,747 --> 00:05:03,648 DISEASE OR INFIRMITY. 142 00:05:03,648 --> 00:05:07,352 SO IN THIS CONSTRUCT, ON THE 143 00:05:07,352 --> 00:05:10,822 LEFT, WELL-BEING AND EMOTIONAL 144 00:05:10,822 --> 00:05:12,123 WELL-BEING PART OF THIS IS PART 145 00:05:12,123 --> 00:05:13,291 OF HEALTH, IS AN IMPORTANT 146 00:05:13,291 --> 00:05:14,359 COMPONENT OF HEALTH. 147 00:05:14,359 --> 00:05:16,661 SO HOW DO WE RECOGNIZE THESE TWO 148 00:05:16,661 --> 00:05:17,629 THINGS, RIGHT? 149 00:05:17,629 --> 00:05:20,799 AND AS I WAS SORT OF THINKING 150 00:05:20,799 --> 00:05:22,200 ABOUT THIS MYSELF, IT OCCURRED 151 00:05:22,200 --> 00:05:26,171 TO ME JUST AS I WAS MAKING THESE 152 00:05:26,171 --> 00:05:27,572 SLIDES THAT A LOT OF THE 153 00:05:27,572 --> 00:05:29,274 COMPONENTS THAT WE SEE ON THE 154 00:05:29,274 --> 00:05:32,010 RIGHT-HAND SIDE AS PART OF 155 00:05:32,010 --> 00:05:33,244 WELL-BEING, WE IN OUR 156 00:05:33,244 --> 00:05:34,879 CONVERSATIONS ABOUT HEALTH, WE 157 00:05:34,879 --> 00:05:37,182 TEND TO CALL THEM DETERMINANTS, 158 00:05:37,182 --> 00:05:37,983 RIGHT? 159 00:05:37,983 --> 00:05:39,551 THESE SOCIAL -- WHAT WE CALL THE 160 00:05:39,551 --> 00:05:42,520 SOCIAL DETERMINANTS OF HEALTH. 161 00:05:42,520 --> 00:05:44,289 ENVIRONMENTAL, SOCIAL, 162 00:05:44,289 --> 00:05:45,156 EDUCATION, ECONOMIC. 163 00:05:45,156 --> 00:05:47,025 AND THEN THERE'S THE 164 00:05:47,025 --> 00:05:47,859 HEALTH-RELATED BEHAVIORS THAT 165 00:05:47,859 --> 00:05:49,661 ARE KIND OF IN BETWEEN, RIGHT? 166 00:05:49,661 --> 00:05:51,096 THEY'RE PART OF HEALTH, THEY'RE 167 00:05:51,096 --> 00:05:52,030 PART OF THE DETERMINANTS, 168 00:05:52,030 --> 00:05:52,764 THEY'RE SORT OF IN BETWEEN 169 00:05:52,764 --> 00:05:53,698 THERE. 170 00:05:53,698 --> 00:05:55,900 SO YOU CAN SEE, IT'S JUST A 171 00:05:55,900 --> 00:05:58,169 DIFFERENT WAY TO THINK ABOUT THE 172 00:05:58,169 --> 00:06:00,372 SAME THINGS. 173 00:06:00,372 --> 00:06:02,874 BUT I THINK IT'S IMPORTANT THAT 174 00:06:02,874 --> 00:06:06,811 WE DON'T GET CONFUSED WITH OUR 175 00:06:06,811 --> 00:06:08,113 LABELS, AND IT'S IMPORTANT THAT 176 00:06:08,113 --> 00:06:10,115 WE CREATE A CONVERSATION THAT 177 00:06:10,115 --> 00:06:11,182 CAN TRANSLATE BETWEEN THESE 178 00:06:11,182 --> 00:06:11,983 DIFFERENT VIEWPOINTS. 179 00:06:11,983 --> 00:06:18,823 THAT'S NOT GOING TO BE EASY. 180 00:06:18,823 --> 00:06:23,795 SO IT'S ALMOST LIKE HEALTH AND 181 00:06:23,795 --> 00:06:25,897 WELL-BEING ARE NOT REALLY -- THE 182 00:06:25,897 --> 00:06:27,499 RELEVANT QUESTION IS NOT SO MUCH 183 00:06:27,499 --> 00:06:29,134 WHICH IS PART OF WHICH. 184 00:06:29,134 --> 00:06:30,468 THEY'RE PART OF EACH OTHER. 185 00:06:30,468 --> 00:06:32,003 AND SO THAT'S WHY I THINK THIS 186 00:06:32,003 --> 00:06:34,806 IS KIND OF THIS IMAGE IS MORE 187 00:06:34,806 --> 00:06:36,675 APT, I THINK, FOR US TO REALLY 188 00:06:36,675 --> 00:06:39,344 START, YOU KNOW, THINKING ABOUT 189 00:06:39,344 --> 00:06:41,413 IT. 190 00:06:41,413 --> 00:06:43,415 AND THE REASON THIS IS SO 191 00:06:43,415 --> 00:06:49,854 IMPORTANT IS THAT -- THIS TOPIC 192 00:06:49,854 --> 00:06:50,755 OF WELL-BEING AND HEALTH, OF 193 00:06:50,755 --> 00:06:52,257 COURSE, IS OF INTEREST NOT ONLY 194 00:06:52,257 --> 00:06:54,025 TO NICCH BUT MANY OTHER FEDERAL 195 00:06:54,025 --> 00:06:54,392 AGENCIES. 196 00:06:54,392 --> 00:06:58,263 I'VE ALREADY MENTIONED THE V.A. 197 00:06:58,263 --> 00:07:01,633 THEIR PROGRAM ON WHOLE HEALTH IS 198 00:07:01,633 --> 00:07:03,601 REALLY -- NOT ONLY ARE THEY 199 00:07:03,601 --> 00:07:04,569 IMPLEMENTING IT ALREADY IN 200 00:07:04,569 --> 00:07:05,770 HEALTHCARE, IT'S THERE, BUT 201 00:07:05,770 --> 00:07:08,406 THEY'RE ALSO DEVELOPING A BRIEF 202 00:07:08,406 --> 00:07:09,407 WELL-BEING MEASURE THAT CAN BE 203 00:07:09,407 --> 00:07:11,142 USED TO ASSESS HOW WELL VAT RANS 204 00:07:11,142 --> 00:07:16,014 VETERANSARE ABLE TO ENGAGE IN WT 205 00:07:16,014 --> 00:07:17,148 MATTERS TO THEM AND THEY'RE IN 206 00:07:17,148 --> 00:07:18,583 THE MIDDLE OF DEVELOPING THIS 207 00:07:18,583 --> 00:07:19,217 AND IMPLEMENTING THIS. 208 00:07:19,217 --> 00:07:20,852 AT THE SAME TIME, THE OFFICE OF 209 00:07:20,852 --> 00:07:22,253 DISEASE PREVENTION AND HEALTH 210 00:07:22,253 --> 00:07:25,857 PROMOTION, THE ODPHP IN 211 00:07:25,857 --> 00:07:26,658 PARTNERSHIP WITH THE SURGEON 212 00:07:26,658 --> 00:07:28,359 GENERAL'S OFFICE, THE OFFICE OF 213 00:07:28,359 --> 00:07:29,461 THE ASSISTANT SECRETARY OF 214 00:07:29,461 --> 00:07:33,264 HEALTH, OASH, THE CDC, THE V.A. 215 00:07:33,264 --> 00:07:34,332 AND NICCH AND OTHERS HAVE ALL 216 00:07:34,332 --> 00:07:37,135 BEEN EXPLORING WAYS TO 217 00:07:37,135 --> 00:07:38,870 UNDERSTAND MEASURE AND 218 00:07:38,870 --> 00:07:40,105 ULTIMATELY ENHANCE WELL-BEING IN 219 00:07:40,105 --> 00:07:41,740 ORDER TO INFORM THE HEALTHY 220 00:07:41,740 --> 00:07:44,409 PEOPLE INITIATIVE, INCLUDING 221 00:07:44,409 --> 00:07:46,277 IMPLEMENTATION OF THE OVERALL 222 00:07:46,277 --> 00:07:47,045 HEALTH AND WELL-BEING MEASURE IN 223 00:07:47,045 --> 00:07:50,248 THE DEVELOPMENT OF THE HEALTHY 224 00:07:50,248 --> 00:07:50,682 PEOPLE 2040 PLAN. 225 00:07:50,682 --> 00:07:53,118 NOW THIS IS A WHOLE LOT OF 226 00:07:53,118 --> 00:07:54,652 JARGON, BUT IT IS BASICALLY 227 00:07:54,652 --> 00:07:57,388 TELLING YOU THAT THE TOPIC OF 228 00:07:57,388 --> 00:08:01,092 WELL-BEING IS FRONT AND CENTER 229 00:08:01,092 --> 00:08:03,695 IN THE AGENDA FOR MANY DIFFERENT 230 00:08:03,695 --> 00:08:04,529 FEDERAL AGENCY, AND THIS IS 231 00:08:04,529 --> 00:08:06,131 GOING TO HAVE IMPORTANT 232 00:08:06,131 --> 00:08:10,101 REPERCUSSIONS DOWN THE LINE. 233 00:08:10,101 --> 00:08:12,604 SO ALL THIS WORK THAT THE 234 00:08:12,604 --> 00:08:14,672 WELL-BEING RESEARCH NETWORKS ARE 235 00:08:14,672 --> 00:08:17,008 DOING IS AND WILL CONTINUE -- 236 00:08:17,008 --> 00:08:19,811 WILL GROW IN IMPORTANCE, IN MY 237 00:08:19,811 --> 00:08:21,713 OPINION, TO INFORM THESE 238 00:08:21,713 --> 00:08:23,114 BURGEONING INITIATIVES 239 00:08:23,114 --> 00:08:24,115 GOVERNMENT-WIDE BECAUSE WHEN WE 240 00:08:24,115 --> 00:08:25,750 SHOW UP AT THESE MEETINGS AND WE 241 00:08:25,750 --> 00:08:27,952 SAY, WE HAVE A GROUP, WE HAVE A 242 00:08:27,952 --> 00:08:30,355 NETWORK THAT'S ALREADY DOING 243 00:08:30,355 --> 00:08:31,022 THIS SCIENTIFICALLY AND IS 244 00:08:31,022 --> 00:08:33,324 REALLY GETTING INTO AND USING 245 00:08:33,324 --> 00:08:35,126 SCIENTIFIC METHODS TO TRY TO 246 00:08:35,126 --> 00:08:36,795 REALLY BRING SOME CLARITY TO THE 247 00:08:36,795 --> 00:08:42,500 AREA, THEY LISTEN. 248 00:08:42,500 --> 00:08:44,569 AND THE RIGOR THE RESEARCH IS 249 00:08:44,569 --> 00:08:46,838 KEY. 250 00:08:46,838 --> 00:08:48,306 THIS IS SO IMPORTANT AND THIS IS 251 00:08:48,306 --> 00:08:51,876 WHAT THIS GROUP CAN MEAN, CAN 252 00:08:51,876 --> 00:08:52,210 BRING. 253 00:08:52,210 --> 00:08:54,145 SO THROUGHOUT THIS MEETING, I 254 00:08:54,145 --> 00:08:55,713 ENCOURAGE YOU TO BE ATTENTIVE TO 255 00:08:55,713 --> 00:08:57,148 HOW WORDS ARE BEING USED, AND 256 00:08:57,148 --> 00:08:59,317 HOW BY WORKING TOGETHER, WE CAN 257 00:08:59,317 --> 00:09:01,486 HELP BRING CLARITY TO A COMPLEX 258 00:09:01,486 --> 00:09:03,788 AND CHALLENGING AREA. 259 00:09:03,788 --> 00:09:06,124 SO THANK YOU ALL FOR BEING HERE, 260 00:09:06,124 --> 00:09:09,494 AND I LOOK FORWARD TO HEARING 261 00:09:09,494 --> 00:09:12,564 FROM ALL OF YOU TODAY. 262 00:09:12,564 --> 00:09:20,638 [APPLAUSE] 263 00:09:20,638 --> 00:09:22,907 >> WELL, GOOD MORNING. 264 00:09:22,907 --> 00:09:26,811 I WILL ALSO JUST ECHO A WELCOME 265 00:09:26,811 --> 00:09:28,146 TO ALL OF YOU WHO ARE HERE IN 266 00:09:28,146 --> 00:09:29,113 THE ROOM AS WELL AS THOSE OF YOU 267 00:09:29,113 --> 00:09:33,518 WHO ARE JOINING US ONLINE. 268 00:09:33,518 --> 00:09:36,588 I'M AMY KELLEY, DEPUTY DIRECTOR 269 00:09:36,588 --> 00:09:37,255 AT THE NATIONAL INSTITUTE ON 270 00:09:37,255 --> 00:09:38,456 AGING, AND IT IS REALLY JUST A 271 00:09:38,456 --> 00:09:39,757 PRIVILEGE TO BE HERE WITH YOU 272 00:09:39,757 --> 00:09:42,627 ALL TODAY FOR THIS IMPORTANT 273 00:09:42,627 --> 00:09:43,394 DISCUSSION. 274 00:09:43,394 --> 00:09:45,663 IT'S BECAUSE ALL OF YOU IN YOUR 275 00:09:45,663 --> 00:09:47,665 COMMUNITY OF NETWORKS THAT WE'RE 276 00:09:47,665 --> 00:09:50,935 MAKING SUCH GRATED A VANS IN THE 277 00:09:50,935 --> 00:09:52,503 STUDY OF EMOTIONAL WELL-BEING 278 00:09:52,503 --> 00:09:56,274 AND REALLY THAT PIV TO PIVOTALN 279 00:09:56,274 --> 00:09:57,375 HEALTH ACROSS THE LIFE COURSE, 280 00:09:57,375 --> 00:09:58,610 SO I JUST APPRECIATE EVERYBODY 281 00:09:58,610 --> 00:10:00,445 TAKING THE TIME TO BE HERE WITH 282 00:10:00,445 --> 00:10:03,481 US AND TO SHARE ALL THAT YOU ARE 283 00:10:03,481 --> 00:10:04,082 DOING. 284 00:10:04,082 --> 00:10:05,783 FIRST, I JUST WANTED TO START 285 00:10:05,783 --> 00:10:08,987 WITH A LITTLE BIT OF THE RECENT 286 00:10:08,987 --> 00:10:10,622 HISTORY OF THIS GROUP OF 287 00:10:10,622 --> 00:10:12,357 NETWORKS, SO AS MANY OF YOU ARE 288 00:10:12,357 --> 00:10:16,327 AWARE, BACK IN 2019, THE 289 00:10:16,327 --> 00:10:17,262 NATIONAL CENTER OF COMPLEMENTARY 290 00:10:17,262 --> 00:10:19,063 AND INTEGRATIVE HEALTH, THE 291 00:10:19,063 --> 00:10:20,031 NATIONAL INSTITUTE OF CHILD 292 00:10:20,031 --> 00:10:21,699 HEALTH AND HUMAN DEVELOPMENT, AS 293 00:10:21,699 --> 00:10:23,835 WELL AS THE NATIONAL INSTITUTE 294 00:10:23,835 --> 00:10:25,603 ON AGING, TOGETHER RELEASED THE 295 00:10:25,603 --> 00:10:26,738 REQUEST FOR APPLICATIONS FOR 296 00:10:26,738 --> 00:10:32,277 THIS HIGH PRIORITY EWB NETWORKS, 297 00:10:32,277 --> 00:10:34,979 EMOTIONAL WE WEB NETWORKS. 298 00:10:34,979 --> 00:10:37,715 SO THAT RFA LED TO THE FORMATION 299 00:10:37,715 --> 00:10:38,950 OF THESE SIX NETWORKS YOU CAN 300 00:10:38,950 --> 00:10:40,585 SEE HERE, WITH FUNDING AND 301 00:10:40,585 --> 00:10:42,253 CO-FUNDING FROM NIH PARTNERS. 302 00:10:42,253 --> 00:10:45,390 ALL OF WHOM REALLY INVESTED IN 303 00:10:45,390 --> 00:10:47,825 THE NETWORK COLLABORATIONS TO 304 00:10:47,825 --> 00:10:49,093 ADVANCE SCIENCE AND EMOTIONAL 305 00:10:49,093 --> 00:10:51,329 WELL-BEING. 306 00:10:51,329 --> 00:10:53,364 SO I WANTED TO GO THROUGH JUST A 307 00:10:53,364 --> 00:10:55,133 COUPLE OF QUICK SLIDES, SOME OF 308 00:10:55,133 --> 00:10:58,436 WHAT I SEE AS THE IMPORTANT 309 00:10:58,436 --> 00:11:00,371 ADVANCES TO SHARE WITH YOU SOME 310 00:11:00,371 --> 00:11:02,240 HIGHLIGHTS FROM THE NETWORK SO 311 00:11:02,240 --> 00:11:05,410 FAR. 312 00:11:05,410 --> 00:11:10,114 FIRST IS THIS PUBLICATION FROM 313 00:11:10,114 --> 00:11:11,516 PARK AND COLLEAGUES IN 2022. 314 00:11:11,516 --> 00:11:14,052 THIS PROVIDES AN EWB ONTOLOGY. 315 00:11:14,052 --> 00:11:17,021 SO TRYING TO GET A NEW AND MORE 316 00:11:17,021 --> 00:11:19,424 INTEGRATED CONCEPTUALIZATION OF 317 00:11:19,424 --> 00:11:20,425 EMOTIONAL WELL-BEING SO THAT WE 318 00:11:20,425 --> 00:11:22,961 CAN BRING GREATER CLARITY AND 319 00:11:22,961 --> 00:11:25,263 MORE COHESIVE FOUNDATION TO THE 320 00:11:25,263 --> 00:11:27,365 SCIENCE AND TO THE FUTURE WORK. 321 00:11:27,365 --> 00:11:31,235 I ALSO AM HIGHLIGHTING HERE ONE 322 00:11:31,235 --> 00:11:33,071 OF EIGHT OPINION PIECES OR 323 00:11:33,071 --> 00:11:34,973 COMMENTARIES THAT WERE FEATURED 324 00:11:34,973 --> 00:11:38,543 ALONG WITH THE PARK ARTICLE. 325 00:11:38,543 --> 00:11:40,011 THIS PIECE, WHICH WAS AUTHORED 326 00:11:40,011 --> 00:11:41,713 BY SOME NIH LEADERS, REALLY 327 00:11:41,713 --> 00:11:44,115 PROMPTS FURTHER CONSIDERATION OF 328 00:11:44,115 --> 00:11:47,051 THE ISSUES THAT ARE RELATED TO 329 00:11:47,051 --> 00:11:50,254 OPERATIONALIZING THESE MEASURES. 330 00:11:50,254 --> 00:11:51,923 NEXT, A COUPLE OF PUBLICATIONS 331 00:11:51,923 --> 00:11:54,826 THAT I WANTED TO HIGHLIGHT IS 332 00:11:54,826 --> 00:11:56,494 THAT WE'VE SEEN MULTIPLE 333 00:11:56,494 --> 00:11:57,996 SYSTEMATIC REVIEWS COMING OUT 334 00:11:57,996 --> 00:12:00,398 FROM THE EFFORTS OF NETWORK 335 00:12:00,398 --> 00:12:00,865 INVESTIGATORS. 336 00:12:00,865 --> 00:12:03,267 I'M FEATURING TWO HERE THAT ARE 337 00:12:03,267 --> 00:12:05,136 ON THE SUBJECTIVE AND THE NEURAL 338 00:12:05,136 --> 00:12:06,771 MEASURES OF EMOTIONAL 339 00:12:06,771 --> 00:12:07,772 WELL-BEING, BUT AGAIN, I JUST 340 00:12:07,772 --> 00:12:09,507 WANT TO REITERATE THAT THESE ARE 341 00:12:09,507 --> 00:12:12,343 JUST A SMALL TASTE OF THE WORK 342 00:12:12,343 --> 00:12:17,048 THAT IS BOTH CURRENT AND ONGOING 343 00:12:17,048 --> 00:12:19,684 IN-PROGRESS EFFORTS. 344 00:12:19,684 --> 00:12:20,985 I ALSO WANTED TO HIGHLIGHT SOME 345 00:12:20,985 --> 00:12:22,620 OF THE NETWORK CONVENINGS, AND 346 00:12:22,620 --> 00:12:25,223 JUST LAST WEEK, WE SAW THE 347 00:12:25,223 --> 00:12:28,026 EMOTICON AND THE M3EWB NETWORKS 348 00:12:28,026 --> 00:12:30,261 HOLD AN EMOTIONAL WELL-BEING 349 00:12:30,261 --> 00:12:32,130 RESEARCH SUMMIT THAT WAS 350 00:12:32,130 --> 00:12:33,865 SCHEDULED RIGHT BEFORE THE 351 00:12:33,865 --> 00:12:34,932 SOCIETY OF BEHAVIORAL MEDICINE 352 00:12:34,932 --> 00:12:37,168 ANNUAL MEETING IN PHILADELPHIA. 353 00:12:37,168 --> 00:12:39,370 THERE'S MANY OTHER EXAMPLES OF 354 00:12:39,370 --> 00:12:41,239 CONVENINGS THAT THE NETWORKS 355 00:12:41,239 --> 00:12:42,874 HAVE PLANNED AND IMPLEMENTED. 356 00:12:42,874 --> 00:12:48,079 THESE INCLUDE SEMINARS, GRANTEE 357 00:12:48,079 --> 00:12:49,113 RETREATS, WORKSHOPS, ACTIVITIES 358 00:12:49,113 --> 00:12:50,448 THAT ARE SPECIFICALLY DESIGNED 359 00:12:50,448 --> 00:12:52,383 AROUND CAREER DEVELOPMENT AND 360 00:12:52,383 --> 00:12:54,018 MENTORSHIP. 361 00:12:54,018 --> 00:12:56,687 AND THEN THE LAST PIECE I WANTED 362 00:12:56,687 --> 00:12:59,257 TO HIGHLIGHT OF EXCITING 363 00:12:59,257 --> 00:13:01,993 NETWOINFORMATION FROM THE NETWOS 364 00:13:01,993 --> 00:13:02,860 DISSEMINATION. 365 00:13:02,860 --> 00:13:04,862 WE HAVE SEEN WORK TO PROMOTE 366 00:13:04,862 --> 00:13:06,297 DISSEMINATION OF NEW AND 367 00:13:06,297 --> 00:13:07,899 EMERGING EWB SCIENCE. 368 00:13:07,899 --> 00:13:10,601 THIS HAS INCLUDED A 369 00:13:10,601 --> 00:13:12,136 COLLABORATION WITH THE STORY 370 00:13:12,136 --> 00:13:14,005 FORM SCIENCE TEAM AROUND HOW TO 371 00:13:14,005 --> 00:13:14,939 EFFECTIVELY COMMUNICATE THIS 372 00:13:14,939 --> 00:13:17,075 WORK TO THE PUBLIC. 373 00:13:17,075 --> 00:13:20,478 AS WELL AS SEVERAL COURSES THAT 374 00:13:20,478 --> 00:13:23,347 FOCUS ON EMOTIONAL WELL-BEING 375 00:13:23,347 --> 00:13:25,483 THAT ALLOW FOR DIDACTIC 376 00:13:25,483 --> 00:13:26,851 OPPORTUNITIES TO UNDERSTAND THE 377 00:13:26,851 --> 00:13:30,888 SCIENCE BUT ALSO BY DOING SO, 378 00:13:30,888 --> 00:13:32,056 PROVIDE OPPORTUNITY FOR EARLY 379 00:13:32,056 --> 00:13:33,324 EXPOSURE TO WORK IN THESE AREAS 380 00:13:33,324 --> 00:13:35,660 THAT MIGHT NOT OTHERWISE BE 381 00:13:35,660 --> 00:13:38,096 POSSIBLE. 382 00:13:38,096 --> 00:13:41,432 I ALSO JUST WANTED TO PIVOT A 383 00:13:41,432 --> 00:13:43,634 LITTLE TO TALK ABOUT OUR 384 00:13:43,634 --> 00:13:45,169 INTEREST AT NIA EVEN MORE 385 00:13:45,169 --> 00:13:46,804 BROADLY IN EMOTIONAL WELL-BEING. 386 00:13:46,804 --> 00:13:48,539 TO THAT END, I WANTED JUST TO 387 00:13:48,539 --> 00:13:53,077 SHARE WITH YOU THAT NIA LEADS A 388 00:13:53,077 --> 00:13:54,479 MULTIDISCIPLINARY EFFORT TO 389 00:13:54,479 --> 00:13:56,314 STUDY AGING, AND A RANGE OF 390 00:13:56,314 --> 00:14:00,151 SUPPORTING RESEARCH THAT OVERALL 391 00:14:00,151 --> 00:14:02,153 WORKS TO ADVANCE THE HEALTHY AND 392 00:14:02,153 --> 00:14:03,454 ACTIVE YEARS OF LIFE. 393 00:14:03,454 --> 00:14:06,691 SO EMOTIONAL WELL-BEING IS A 394 00:14:06,691 --> 00:14:07,692 REALLY CRITICAL ASPECT OF 395 00:14:07,692 --> 00:14:08,493 HEALTHY AGING. 396 00:14:08,493 --> 00:14:10,561 IT'S BOTH A PREDICTOR AND IT AN 397 00:14:10,561 --> 00:14:11,062 OUT COME. 398 00:14:11,062 --> 00:14:13,164 AND SO WE RECOGNIZE THE 399 00:14:13,164 --> 00:14:15,032 CENTRALITY OF THIS ISSUE TO 400 00:14:15,032 --> 00:14:20,404 HEALTH, ACCORDINGLY, EWB 401 00:14:20,404 --> 00:14:22,106 RESEARCH IS PRIORITIZED WITHIN 402 00:14:22,106 --> 00:14:23,441 OUR CURRENT STRATEGIC DIRECTIONS 403 00:14:23,441 --> 00:14:24,542 FOR RESEARCH. 404 00:14:24,542 --> 00:14:25,977 AND TO DIVE INTO THAT A LITTLE 405 00:14:25,977 --> 00:14:28,346 BIT FURTHER, YOU CAN SEE IN THIS 406 00:14:28,346 --> 00:14:29,447 DOCUMENT, EVE HIGHLIGHTED HERE 407 00:14:29,447 --> 00:14:31,749 ON THE RIGHT SEVERAL AREAS THAT 408 00:14:31,749 --> 00:14:33,951 ARE CURRENT STRATEGIC PRIORITIES 409 00:14:33,951 --> 00:14:36,354 INCLUDE RELATED TO EWB RESEARCH. 410 00:14:36,354 --> 00:14:40,324 SO THIS INCLUDES FURTHERING OUR 411 00:14:40,324 --> 00:14:41,159 UNDERSTANDING OF THE 412 00:14:41,159 --> 00:14:43,261 PSYCHOLOGICAL ASPECTS OF AGING, 413 00:14:43,261 --> 00:14:44,662 DEVELOPING INTERVENTIONS THAT 414 00:14:44,662 --> 00:14:47,732 MAINTAIN HEALTH AND WELL-BEING, 415 00:14:47,732 --> 00:14:48,900 IDENTIFYING FACTORS ASSOCIATED 416 00:14:48,900 --> 00:14:51,536 WITH SUCCESSFUL AGING AND 417 00:14:51,536 --> 00:14:54,539 RESILIENCE, AND ELUCIDATING 418 00:14:54,539 --> 00:14:55,940 HEALTH DISPARITIES THAT RELATE 419 00:14:55,940 --> 00:14:57,241 TO AGENTING IN ORDER TO PROMOTE 420 00:14:57,241 --> 00:14:58,042 BETTER HEALTH FOR ALL. 421 00:14:58,042 --> 00:14:59,544 I ALSO WOULD HIGHLIGHT HERE THAT 422 00:14:59,544 --> 00:15:00,545 IN THE COMING YEAR, WE'RE GOING 423 00:15:00,545 --> 00:15:04,148 TO BE SEEKING PUBLIC FEEDBACK ON 424 00:15:04,148 --> 00:15:05,950 OUR NEXT FIVE YEARS OF STRATEGIC 425 00:15:05,950 --> 00:15:07,652 SCIENTIFIC PRIORITIES, AND SO 426 00:15:07,652 --> 00:15:08,953 WOULD WELCOME YOU TO LOOK OUT 427 00:15:08,953 --> 00:15:10,354 FOR THOSE OPPORTUNITIES AND 428 00:15:10,354 --> 00:15:15,760 PROVIDE US WITH YOUR INPUT. 429 00:15:15,760 --> 00:15:18,329 AND THEN LASTLY, I JUST WANTED 430 00:15:18,329 --> 00:15:20,898 TO HIGHLIGHT MORE SPECIFICALLY 431 00:15:20,898 --> 00:15:24,635 THE NIA-FUNDED NETWORKS, THE NEW 432 00:15:24,635 --> 00:15:26,437 B AND NEW BRAIN AGING CENTER. 433 00:15:26,437 --> 00:15:29,974 THROUGH THESE NETWORKS, NIA IS 434 00:15:29,974 --> 00:15:31,275 EXPLORING KEY INTERESTS IN THE 435 00:15:31,275 --> 00:15:32,677 MECHANISTIC RESEARCH AND THE 436 00:15:32,677 --> 00:15:34,278 ROLE OF EMOTIONAL WELL-BEING AND 437 00:15:34,278 --> 00:15:35,846 HEALTH AND AGING, MEASUREMENT 438 00:15:35,846 --> 00:15:38,983 DEVELOPMENT AND VALIDATION, 439 00:15:38,983 --> 00:15:41,185 BIOMARKERS, TECHNOLOGY, AND 440 00:15:41,185 --> 00:15:42,954 OUTCOME MEASURE DEVELOPMENT, AS 441 00:15:42,954 --> 00:15:44,689 WELL AS PREVENTION RESEARCH AND 442 00:15:44,689 --> 00:15:46,557 INTERVENTIONS. 443 00:15:46,557 --> 00:15:48,526 SO OUR HOPE IS THAT THROUGH ALL 444 00:15:48,526 --> 00:15:50,695 OF THESE ADVANCEMENTS, WE CAN 445 00:15:50,695 --> 00:15:53,097 PROMOTE A HEIGHTENED WELL-BEING, 446 00:15:53,097 --> 00:15:56,300 AND BETTER TRAJECTORIES OF 447 00:15:56,300 --> 00:15:58,736 HEALTH FOR EVERYONE AS WE AGE 448 00:15:58,736 --> 00:15:59,837 ACROSS THE LIFE COURSE. 449 00:15:59,837 --> 00:16:02,240 SO BOTH FOR CURRENT OLDER ADULTS 450 00:16:02,240 --> 00:16:05,009 AS WELL AS FUTURE GENERATIONS. 451 00:16:05,009 --> 00:16:07,912 WE REALLY ARE GRATEFUL FOR OUR 452 00:16:07,912 --> 00:16:09,614 COLLABORATIONS WITH OUR PARTNERS 453 00:16:09,614 --> 00:16:12,583 ACROSS ALL OF THE EWB NETWORKS. 454 00:16:12,583 --> 00:16:13,884 WE'RE GRATEFUL TO EACH AND EVERY 455 00:16:13,884 --> 00:16:16,087 ONE OF YOU AND YOUR COLLEAGUES 456 00:16:16,087 --> 00:16:17,622 JOINING US THROUGH ZOOM ON YOUR 457 00:16:17,622 --> 00:16:20,057 EFFORTS AND YOUR SUPPORT AND 458 00:16:20,057 --> 00:16:21,459 WOULD ENCOURAGE ANYONE TO REACH 459 00:16:21,459 --> 00:16:24,395 OUT TO THOSE OF US AT NIA IF WE 460 00:16:24,395 --> 00:16:26,397 CAN SUPPORT YOU IN YOUR WORK IN 461 00:16:26,397 --> 00:16:28,466 THIS ARENA, AND I'M JUST GLAD TO 462 00:16:28,466 --> 00:16:30,101 BE HERE WITH ALL OF YOU TODAY 463 00:16:30,101 --> 00:16:32,169 AND I HOPE YOU HAVE A WONDERFUL 464 00:16:32,169 --> 00:16:34,138 MEETING. 465 00:16:34,138 --> 00:16:36,440 AND WITH ALISON'S ABSENCE, I 466 00:16:36,440 --> 00:16:37,375 KNOW SHE'S MISSING BEING HERE 467 00:16:37,375 --> 00:16:38,876 BUT I'M GOING TO HAND IT OFF TO 468 00:16:38,876 --> 00:16:43,981 TRACY. 469 00:16:43,981 --> 00:16:54,158 [APPLAUSE] 470 00:17:16,314 --> 00:17:19,116 >> GOOD MORNING, EVERYBODY. 471 00:17:19,116 --> 00:17:21,085 AND THANK YOU ALL FOR THE 472 00:17:21,085 --> 00:17:22,787 WONDERFUL INTRODUCTION. 473 00:17:22,787 --> 00:17:24,588 I'M TRACY KING. 474 00:17:24,588 --> 00:17:26,624 MANY OF YOU IN THE ROOM KNOW ME 475 00:17:26,624 --> 00:17:28,726 AS ONE OF THE NICHD LIAISONS TO 476 00:17:28,726 --> 00:17:30,828 THIS PROGRAM. 477 00:17:30,828 --> 00:17:32,129 I'M ALSO HERE TODAY WEARING MY 478 00:17:32,129 --> 00:17:33,964 HAT AS THE ASSOCIATE DIRECTOR OF 479 00:17:33,964 --> 00:17:36,100 PREVENTION FOR THE EUNICE 480 00:17:36,100 --> 00:17:37,034 KENNEDY SHRIVER NATIONAL 481 00:17:37,034 --> 00:17:38,169 INSTITUTE OF CHILD HEALTH AND 482 00:17:38,169 --> 00:17:42,606 HUMAN DEVELOPMENT, OR NICHD. 483 00:17:42,606 --> 00:17:43,874 SO I FIRST WANTED TO SAY THANK 484 00:17:43,874 --> 00:17:45,776 YOU TO DR. LANGEVIN AND 485 00:17:45,776 --> 00:17:46,911 DR. KELLEY FOR YOUR LEADERSHIP 486 00:17:46,911 --> 00:17:50,481 IN THIS AREA. 487 00:17:50,481 --> 00:17:52,116 DR. CERNICH AND DR. BIANCHI SEND 488 00:17:52,116 --> 00:17:53,317 THEIR REGRETS FOR MISSING THIS 489 00:17:53,317 --> 00:17:54,919 MORNING, BUT THEY WERE CALLED TO 490 00:17:54,919 --> 00:17:56,387 THE WHITE HOUSE FOR THE LAUNCH 491 00:17:56,387 --> 00:17:59,090 OF THE WOMEN'S HEALTH INITIA 492 00:17:59,090 --> 00:17:59,390 INITIATIVE. 493 00:17:59,390 --> 00:18:00,791 I'M REALLY HONORED TO OPEN THIS 494 00:18:00,791 --> 00:18:01,859 MEETING WITH YOU TODAY AND TO 495 00:18:01,859 --> 00:18:02,860 HAVE THE OPPORTUNITY TO PARTNER 496 00:18:02,860 --> 00:18:05,129 WITH YOU IN THE SPACE FOR 497 00:18:05,129 --> 00:18:10,034 EMOTIONAL WELL-BEING RESEARCH. 498 00:18:10,034 --> 00:18:12,136 WE WOULD LIKE ESPECIALLY TO SEND 499 00:18:12,136 --> 00:18:16,407 OUR APPRECIATION TO DR. ERIN 500 00:18:16,407 --> 00:18:19,243 BURKE QUINLAN AT NICHD, TO 501 00:18:19,243 --> 00:18:21,112 DR. ELIZABETH AT NIA AND ALL THE 502 00:18:21,112 --> 00:18:22,246 MEMBERS OF THE ORGANIZING TEAM 503 00:18:22,246 --> 00:18:23,748 FOR ALL THE WORK YOU'VE PUT INTO 504 00:18:23,748 --> 00:18:26,117 TODAY'S TERRIFIC PROGRAM. 505 00:18:26,117 --> 00:18:27,585 AS HAS BEEN MENTIONED, THE 506 00:18:27,585 --> 00:18:28,586 EMOTIONAL WELL-BEING RESEARCH 507 00:18:28,586 --> 00:18:31,255 NETWORK INVESTIGATORS, ALL OF 508 00:18:31,255 --> 00:18:32,723 YOU HAVE REALLY MADE AMAZING 509 00:18:32,723 --> 00:18:35,760 STRIDES IN THIS SPACE. 510 00:18:35,760 --> 00:18:37,294 AND I AND MY COLLEAGUES AT NICHD 511 00:18:37,294 --> 00:18:38,829 ARE REALLY LOOKING FORWARD TO 512 00:18:38,829 --> 00:18:39,964 SPENDING THE DAY HEARING MORE 513 00:18:39,964 --> 00:18:41,565 ABOUT THE SUCCESSES AND ABOUT 514 00:18:41,565 --> 00:18:43,834 WHERE YOU'RE GOING. 515 00:18:43,834 --> 00:18:45,403 NICHD'S MISSION IS TO LEAD 516 00:18:45,403 --> 00:18:46,637 RESEARCH AND TRAINING TO 517 00:18:46,637 --> 00:18:48,539 UNDERSTAND HUMAN DEVELOPMENT, 518 00:18:48,539 --> 00:18:50,141 IMPROVE REPRODUCTIVE HEALTH, AND 519 00:18:50,141 --> 00:18:52,276 ENHANCE THE LIVES OF CHILDREN, 520 00:18:52,276 --> 00:18:54,245 ADOLESCENTS, AND OPTIMIZE 521 00:18:54,245 --> 00:18:54,979 ABILITIES FOR ALL. 522 00:18:54,979 --> 00:18:57,515 WITHIN THAT CONTEXT, IT'S VITAL 523 00:18:57,515 --> 00:18:58,549 ESPECIALLY FOR ADVANCING THE 524 00:18:58,549 --> 00:19:00,885 HEALTH OF WOMEN, CHILDREN, 525 00:19:00,885 --> 00:19:03,020 ADOLESCENTS, AND PEOPLE WITH 526 00:19:03,020 --> 00:19:03,888 DISABILITIES, THAT WE BETTER 527 00:19:03,888 --> 00:19:06,290 UNDERSTAND HOW TO PROMOTE 528 00:19:06,290 --> 00:19:07,258 WELL-BEING AND THE POSITIVE 529 00:19:07,258 --> 00:19:08,292 FACTORS THAT PROMOTE QUALITY OF 530 00:19:08,292 --> 00:19:08,626 LIFE. 531 00:19:08,626 --> 00:19:12,463 WE ALSO KNOW AS DR. LANGEVIN 532 00:19:12,463 --> 00:19:13,931 MENTIONED THAT THERE'S A STRONG 533 00:19:13,931 --> 00:19:16,467 CONNECTION BETWEEN EMOTIONAL 534 00:19:16,467 --> 00:19:18,769 WELL-BEING AND PHYSICAL HEALTH. 535 00:19:18,769 --> 00:19:19,970 AND AS DR. KELLEY AND OTHERS 536 00:19:19,970 --> 00:19:21,372 HAVE MENTIONED, HEALTH IS NOT 537 00:19:21,372 --> 00:19:23,274 STATIC OVER THE LIFESPAN. 538 00:19:23,274 --> 00:19:27,678 OUR NEEDS, OUR PERSPECTIVES, 539 00:19:27,678 --> 00:19:28,579 DEVELOPMENT, SOCIAL MILIEU, 540 00:19:28,579 --> 00:19:30,481 FAMILY SUPPORT SYSTEMS, CHANGE 541 00:19:30,481 --> 00:19:32,550 OVER TIME AND SOMETIMES REALLY 542 00:19:32,550 --> 00:19:33,551 RAPIDLY WHEN CRITICAL LIFE 543 00:19:33,551 --> 00:19:34,418 EVENTS OCCUR. 544 00:19:34,418 --> 00:19:36,253 THE BIRTH OF A CHILD, INCREASED 545 00:19:36,253 --> 00:19:38,656 WORK RESPONSIBILITIES FROM A JOB 546 00:19:38,656 --> 00:19:40,024 PROMOTION, DEATH OF A FAMILY 547 00:19:40,024 --> 00:19:41,292 MEMBER, OR A CAR ACCIDENT THAT 548 00:19:41,292 --> 00:19:42,726 CAUSES DISABILITY. 549 00:19:42,726 --> 00:19:45,129 THIS MEANS THAT WE NEED TO 550 00:19:45,129 --> 00:19:46,197 UNDERSTAND EMOTIONAL WELL-BEING 551 00:19:46,197 --> 00:19:47,765 ACROSS LIFE STAGES. 552 00:19:47,765 --> 00:19:49,500 AND IN DIFFERENT CONTEXTS. 553 00:19:49,500 --> 00:19:50,801 CONSIDERING THE IMPACT OF EARLY 554 00:19:50,801 --> 00:19:53,304 LIFE EVENTS ON THE TRAJECTORY OF 555 00:19:53,304 --> 00:19:54,438 EMOTIONAL WELL-BEING OVER TIME, 556 00:19:54,438 --> 00:19:56,941 SOCIAL DETERMINANTS OF HEALTH, 557 00:19:56,941 --> 00:19:58,108 ENVIRONMENTAL, BEHAVIORAL, 558 00:19:58,108 --> 00:19:59,877 PSYCHOLOGICAL, AND BIOLOGICAL 559 00:19:59,877 --> 00:20:00,478 FACTORS. 560 00:20:00,478 --> 00:20:02,079 WE NEED TARGETED INTERVENTIONS 561 00:20:02,079 --> 00:20:03,414 THAT ADDRESS THE UNIQUE NEEDS 562 00:20:03,414 --> 00:20:05,683 AND CHALLENGES ENCOUNTERED 563 00:20:05,683 --> 00:20:06,784 ACROSS LIFE STAGES. 564 00:20:06,784 --> 00:20:07,751 PREVENTIVE MEASURES, 565 00:20:07,751 --> 00:20:09,186 INTERVENTIONS FOR CHILDREN 566 00:20:09,186 --> 00:20:10,488 WHO'VE EXPERIENCED ADVERSE 567 00:20:10,488 --> 00:20:11,489 EVENTS, SUPPORT SYSTEMS THAT 568 00:20:11,489 --> 00:20:13,023 PROMOTE LIFELONG EMOTIONAL 569 00:20:13,023 --> 00:20:14,358 HEALTH AND RESILIENCE FOR 570 00:20:14,358 --> 00:20:15,526 EVERYONE, REGARDLESS OF AGE OR 571 00:20:15,526 --> 00:20:18,062 BACKGROUND. 572 00:20:18,062 --> 00:20:19,497 IT'S A DIFFICULT CHALLENGE. 573 00:20:19,497 --> 00:20:22,466 EMOTIONAL WELL-BEING IS COMPLEX, 574 00:20:22,466 --> 00:20:23,367 PARTICULARLY BECAUSE IT MEANS 575 00:20:23,367 --> 00:20:24,168 DIFFERENT THINGS TO DIFFERENT 576 00:20:24,168 --> 00:20:25,736 PEOPLE ACROSS THE LIFESPAN AND 577 00:20:25,736 --> 00:20:26,770 INTERACTS WITH SO MANY FACTORS 578 00:20:26,770 --> 00:20:28,672 THAT CONTRIBUTE TO DISPARITIES. 579 00:20:28,672 --> 00:20:31,609 ADVERSE EVENTS IN CHILDHOOD, 580 00:20:31,609 --> 00:20:33,844 FOOD SECURITY, HOUSING SECURITY, 581 00:20:33,844 --> 00:20:34,979 RACISM, AND THE 582 00:20:34,979 --> 00:20:36,180 INTERSECTIONALITY OF IDENTITY 583 00:20:36,180 --> 00:20:37,848 AND EXPERIENCE ALL HAVE DIRECT 584 00:20:37,848 --> 00:20:39,483 IMPACTS ON EMOTIONAL WELL-BEING 585 00:20:39,483 --> 00:20:40,117 AT EVERY AGE. 586 00:20:40,117 --> 00:20:43,053 FOR INSTANCE, THOSE FROM 587 00:20:43,053 --> 00:20:43,954 MARGINALIZED GROUPS MAY 588 00:20:43,954 --> 00:20:45,022 EXPERIENCE HIGHER LEVELS OF 589 00:20:45,022 --> 00:20:46,156 STRESS OR BARRIERS TO CARE, BOTH 590 00:20:46,156 --> 00:20:47,258 OF WHICH IMPACT WELL-BEING. 591 00:20:47,258 --> 00:20:50,027 FOR THE ELDERLY, THEIR EMOTIONAL 592 00:20:50,027 --> 00:20:50,995 WELL-BEING MAY BE TIED TO 593 00:20:50,995 --> 00:20:52,196 CHANGES IN THEIR BRAIN, 594 00:20:52,196 --> 00:20:53,564 ISOLATION AND LONELINESS AND 595 00:20:53,564 --> 00:20:54,598 LIFE TRANSITIONS. 596 00:20:54,598 --> 00:20:56,467 PEOPLE WITH DISABILITY 597 00:20:56,467 --> 00:20:58,335 EXPERIENCE MARGINALIZATION AND 598 00:20:58,335 --> 00:20:59,503 STIGMA, ALONG WITH BARRIERS DUE 599 00:20:59,503 --> 00:21:01,472 TO LACK OF INCLUSIVE OR 600 00:21:01,472 --> 00:21:02,873 ACCESSIBLE SOCIAL AND PHYSICAL 601 00:21:02,873 --> 00:21:03,574 ENVIRONMENTS. 602 00:21:03,574 --> 00:21:04,642 PROVIDING TAILORED SUPPORT 603 00:21:04,642 --> 00:21:06,110 SYSTEMS TO MEET DIFFERENT 604 00:21:06,110 --> 00:21:07,578 POPULATION NEEDS WILL BE 605 00:21:07,578 --> 00:21:08,679 ESSENTIAL TO SUCCESS. 606 00:21:08,679 --> 00:21:09,847 CHILDREN MAY NEED MECHANISMS 607 00:21:09,847 --> 00:21:11,215 THAT TEACH THEM EMOTIONAL 608 00:21:11,215 --> 00:21:12,116 WELL-BEING THROUGH PLAY. 609 00:21:12,116 --> 00:21:13,584 PEOPLE WITH DISABILITIES MAY 610 00:21:13,584 --> 00:21:14,885 NEED ACCOMMODATIONS AND 611 00:21:14,885 --> 00:21:16,120 UNDERSTANDING FROM THEIR SOCIAL 612 00:21:16,120 --> 00:21:17,254 SUPPORT SYSTEMS TO NAVIGATE 613 00:21:17,254 --> 00:21:19,290 THEIR CHALLENGES EFFECTIVELY. 614 00:21:19,290 --> 00:21:20,591 WE NEED TO UNDERSTAND THESE 615 00:21:20,591 --> 00:21:22,226 NUANCES OF EMOTIONAL WELL-BEING 616 00:21:22,226 --> 00:21:23,928 FOR DIFFERENT GROUPS AND TO 617 00:21:23,928 --> 00:21:25,629 DEVELOP ATTUNED INTERVENTIONS 618 00:21:25,629 --> 00:21:27,531 AND PROMOTE HEALTH EQUITY. 619 00:21:27,531 --> 00:21:28,966 THIS INITIATIVE HAS SHOWN THE 620 00:21:28,966 --> 00:21:31,802 POWER AND VALUE OF TAKING A 621 00:21:31,802 --> 00:21:32,736 MULTI-INSTITUTE, 622 00:21:32,736 --> 00:21:33,938 MULTIDISCIPLINARY APPROACH TO 623 00:21:33,938 --> 00:21:34,805 ADVANCE EMOTIONAL WELL-BEING 624 00:21:34,805 --> 00:21:35,539 RESEARCH. 625 00:21:35,539 --> 00:21:37,007 WE CAN'T TACKLE SOMETHING AS 626 00:21:37,007 --> 00:21:38,609 COMPLEX AS EMOTIONAL WELL-BEING 627 00:21:38,609 --> 00:21:40,411 WITHOUT A COMPREHENSIVE 628 00:21:40,411 --> 00:21:42,479 UNDERSTANDING AND WELL-ROUNDED 629 00:21:42,479 --> 00:21:43,080 INTERVENTIONS. 630 00:21:43,080 --> 00:21:44,582 THIS IS WHY WE NEED SO MANY 631 00:21:44,582 --> 00:21:45,349 DISCIPLINES TO COME TOGETHER FOR 632 00:21:45,349 --> 00:21:47,084 THIS WORK. 633 00:21:47,084 --> 00:21:48,919 SO THANK YOU ONCE AGAIN TO NICCH 634 00:21:48,919 --> 00:21:51,355 FOR YOUR LEADERSHIP. 635 00:21:51,355 --> 00:21:52,856 THANKS TO ALL OF YOU 636 00:21:52,856 --> 00:21:53,857 INVESTIGATORS FOR ALL THE WORK 637 00:21:53,857 --> 00:21:55,793 YOU'VE BEEN DOING SO FAR. 638 00:21:55,793 --> 00:21:57,161 OUR CHALLENGE TODAY IS TO KEEP 639 00:21:57,161 --> 00:21:58,896 THINKING OF NOVEL INTERVENTIONS, 640 00:21:58,896 --> 00:22:01,198 NEW PARTNERS, AND BROAD 641 00:22:01,198 --> 00:22:02,833 APPROACHES TO IMPROVE EMOTIONAL 642 00:22:02,833 --> 00:22:03,801 WELL-BEING FOR ALL OF OUR 643 00:22:03,801 --> 00:22:05,069 POPULATIONS. 644 00:22:05,069 --> 00:22:07,638 AND SO NOW I'D LIKE TO INTRODUCE 645 00:22:07,638 --> 00:22:10,641 OUR NEXT SPEAKER, WHO IS THE 646 00:22:10,641 --> 00:22:12,109 DIRECTOR OF THE DIVISION OF 647 00:22:12,109 --> 00:22:14,511 EXTRAMURAL RESEARCH AT NICCH, 648 00:22:14,511 --> 00:22:15,346 DR. EMMELINE EDWARDS. 649 00:22:15,346 --> 00:22:16,680 DR. EDWARDS IS GOING TO PROVIDE 650 00:22:16,680 --> 00:22:17,948 AN OVERVIEW OF THE EMOTIONAL 651 00:22:17,948 --> 00:22:19,116 WELL-BEING INITIATIVE AND 652 00:22:19,116 --> 00:22:19,984 HIGHLIGHT RELATED ACTIVITIES 653 00:22:19,984 --> 00:22:22,186 THAT CAN LEVERAGE THE WORK OF 654 00:22:22,186 --> 00:22:22,920 THE EMOTIONAL WELL-BEING 655 00:22:22,920 --> 00:22:23,187 NETWORKS. 656 00:22:23,187 --> 00:22:24,288 THANK YOU VERY MUCH. 657 00:22:24,288 --> 00:22:24,555 [APPLAUSE] 658 00:22:24,555 --> 00:22:34,098 >> THANK YOU, TRACY. 659 00:22:34,098 --> 00:22:36,400 CAN YOU SEE THAT? 660 00:22:36,400 --> 00:22:38,268 OKAY. 661 00:22:38,268 --> 00:22:39,670 SO GOOD MORNING, EVERYBODY. 662 00:22:39,670 --> 00:22:42,306 I'M SORRY I CAN'T BE WITH YOU IN 663 00:22:42,306 --> 00:22:42,539 PERSON. 664 00:22:42,539 --> 00:22:46,276 I AM ACTUALLY JOINING FROM NEW 665 00:22:46,276 --> 00:22:48,746 YORK CITY, AND SO AGAIN, WITH 666 00:22:48,746 --> 00:22:51,448 THE WONDERFUL WORLD OF 667 00:22:51,448 --> 00:22:52,716 TECHNOLOGY, I'M GLAD I'M ABLE TO 668 00:22:52,716 --> 00:22:53,350 REACH YOU. 669 00:22:53,350 --> 00:22:56,120 SO IT'S FUNNY, YESTERDAY WHEN I 670 00:22:56,120 --> 00:23:00,891 ARRIVED IN NEW YORK, I WAS 671 00:23:00,891 --> 00:23:01,492 PERUSING "THE NEW YORK TIMES" 672 00:23:01,492 --> 00:23:04,395 AND THERE WAS ACTUALLY AN 673 00:23:04,395 --> 00:23:06,163 ARTICLE THAT CAUGHT MY EYES AND 674 00:23:06,163 --> 00:23:09,400 IT WAS WHO HAS THE SECRET TO 675 00:23:09,400 --> 00:23:10,834 WELL-BEING? 676 00:23:10,834 --> 00:23:13,270 AND THIS ASSOCIATE PROFESSOR OF 677 00:23:13,270 --> 00:23:17,641 PEDIATRICS AT MCMASTER 678 00:23:17,641 --> 00:23:18,842 UNIVERSITY THINKS THAT TODDLERS 679 00:23:18,842 --> 00:23:20,010 ACTUALLY CAN TEACH US A FEW 680 00:23:20,010 --> 00:23:21,912 THINGS ABOUT WELL-BEING. 681 00:23:21,912 --> 00:23:24,448 AND THE RATIONALE WAS THAT 682 00:23:24,448 --> 00:23:26,150 TODDLERS HAVE AN INNATE ABILITY 683 00:23:26,150 --> 00:23:29,953 TO BE CURIOUS, TO DO SOME 684 00:23:29,953 --> 00:23:33,290 SELF-TALK FOR THEMSELF, TO 685 00:23:33,290 --> 00:23:35,092 LAUGH, AND TO BE ENERGETIC. 686 00:23:35,092 --> 00:23:37,995 AND AS YOU CAN SEE, DR. LANGEVIN 687 00:23:37,995 --> 00:23:41,665 AND DR. KELLEY REALLY 688 00:23:41,665 --> 00:23:46,837 HIGHLIGHTED THE INTEREST IN 689 00:23:46,837 --> 00:23:49,473 WELL-BEING IN GENERAL. 690 00:23:49,473 --> 00:23:51,508 AND SO THIS IS SOMETHING THAT AT 691 00:23:51,508 --> 00:23:53,277 NIH, WE HAVE BEEN INTERESTED FOR 692 00:23:53,277 --> 00:23:57,114 A NUMBER OF YEARS AND JUST 693 00:23:57,114 --> 00:23:59,149 GIVING YOU A LITTLE BIT OF -- A 694 00:23:59,149 --> 00:24:02,019 LITTLE WALK THROUGH MEMORY LANE 695 00:24:02,019 --> 00:24:02,386 HERE. 696 00:24:02,386 --> 00:24:06,724 WE STARTED THIS SINCE 2018, WHEN 697 00:24:06,724 --> 00:24:08,358 WE HAD A ROUNDTABLE DISCUSSION. 698 00:24:08,358 --> 00:24:11,328 AND ACTUALLY THERE'S A LITTLE 699 00:24:11,328 --> 00:24:12,496 BIT OF INFORMATION, WE HAD 700 00:24:12,496 --> 00:24:16,567 STARTED WORKING WITH DR. VIVEK 701 00:24:16,567 --> 00:24:18,102 MURTHY IN HIS FIRST TERM AS 702 00:24:18,102 --> 00:24:18,669 SURGEON GENERAL. 703 00:24:18,669 --> 00:24:19,770 SO THAT'S THE WAY THE 704 00:24:19,770 --> 00:24:24,708 CONVERSATION STARTED, AND 705 00:24:24,708 --> 00:24:25,909 UNFORTUNATELY, DR. MURTHY DID 706 00:24:25,909 --> 00:24:26,910 NOT CONTINUE AS SURGEON GENERAL 707 00:24:26,910 --> 00:24:29,747 SO HE DID NOT PARTICIPATE INTO 708 00:24:29,747 --> 00:24:31,115 THE DEVELOPMENT OF THE NETWORK, 709 00:24:31,115 --> 00:24:32,783 BUT VERY MUCH AT THE BEGINNING, 710 00:24:32,783 --> 00:24:34,551 WE HAD THIS CONVERSATION WITH 711 00:24:34,551 --> 00:24:36,820 HIM, AND WE REALIZED HOW MUCH WE 712 00:24:36,820 --> 00:24:39,323 DIDN'T KNOW ABOUT EMOTIONAL 713 00:24:39,323 --> 00:24:40,424 WELL-BEING. 714 00:24:40,424 --> 00:24:42,593 WHAT WERE THE COMPONENTS, 715 00:24:42,593 --> 00:24:44,294 WHETHER THIS WOULD BE DIFFERENT 716 00:24:44,294 --> 00:24:45,529 AT DIFFERENT AGE GROUPS AND 717 00:24:45,529 --> 00:24:48,165 DIFFERENT POPULATIONS. 718 00:24:48,165 --> 00:24:50,067 WE ALSO WERE NOT SURE WHETHER 719 00:24:50,067 --> 00:24:52,336 EMOTIONAL WELL-BEING WOULD BE A 720 00:24:52,336 --> 00:24:55,205 MEDIATOR OF OTHER HEALTH 721 00:24:55,205 --> 00:24:57,207 OUTCOMES OR IF IT WOULD BE AN 722 00:24:57,207 --> 00:24:58,509 OUTCOME IN ITSELF. 723 00:24:58,509 --> 00:25:00,110 WE ALSO WERE INTERESTED IN 724 00:25:00,110 --> 00:25:02,012 UNDERSTANDING IF WE IMPROVE OUR 725 00:25:02,012 --> 00:25:04,448 EMOTIONAL WELL-BEING OR OUR 726 00:25:04,448 --> 00:25:05,449 WELL-BEING, WHAT IMPACT THAT 727 00:25:05,449 --> 00:25:07,551 WOULD HAVE ON NEURAL CIRCUITS 728 00:25:07,551 --> 00:25:09,453 THAT ARE IMPORTANT FOR EMOTIONAL 729 00:25:09,453 --> 00:25:12,156 REGULATION AND COGNITIVE CONT 730 00:25:12,156 --> 00:25:12,389 CONTROL. 731 00:25:12,389 --> 00:25:16,894 WE WERE INTERESTED IN SOME 732 00:25:16,894 --> 00:25:18,195 DEVELOPING INTERVENTION THAT 733 00:25:18,195 --> 00:25:19,963 WOULD DECREASE BURNOUT, REDUCE 734 00:25:19,963 --> 00:25:23,700 STRESS, MANAGE PAIN AND OTHER 735 00:25:23,700 --> 00:25:24,968 MENTAL HEALTH SYMPTOMS IN THIS 736 00:25:24,968 --> 00:25:25,736 AT RISK POPULATION. 737 00:25:25,736 --> 00:25:27,704 SO THAT'S THE CONVERSATION WE 738 00:25:27,704 --> 00:25:30,207 HAD IN APRIL OF 2018, AND FROM 739 00:25:30,207 --> 00:25:33,043 THAT ROUNDTABLE, WE STARTED 740 00:25:33,043 --> 00:25:34,244 ACTUALLY HAVING THOSE 741 00:25:34,244 --> 00:25:36,213 DISCUSSIONS AT THE NIH TO SEE 742 00:25:36,213 --> 00:25:38,749 HOW COULD WE MOVE FORWARD WITH A 743 00:25:38,749 --> 00:25:42,119 RESEARCH AGENDA THAT WOULD 744 00:25:42,119 --> 00:25:44,421 ADDRESS SOME OF THOSE GAPS. 745 00:25:44,421 --> 00:25:47,724 SO WE ACTUALLY WANTED TO ADVANCE 746 00:25:47,724 --> 00:25:50,694 RESEARCH IN THAT AREA, AND 747 00:25:50,694 --> 00:25:52,763 INSTEAD OF DOING THE STANDARD 748 00:25:52,763 --> 00:25:54,631 RFA THAT WE DO AT THE NIH 749 00:25:54,631 --> 00:25:58,468 CALLING FOR PROPOSAL FOR 750 00:25:58,468 --> 00:25:59,536 R01 GRANTS, WE THOUGHT THAT THE 751 00:25:59,536 --> 00:26:04,675 FIELD WAS NOT READY TO APPLY FOR 752 00:26:04,675 --> 00:26:06,577 REGULAR R01 GRANTS, SO WE 753 00:26:06,577 --> 00:26:07,845 THOUGHT THAT THE MECHANISM THAT 754 00:26:07,845 --> 00:26:10,581 WOULD ACTUALLY BRING PEOPLE FROM 755 00:26:10,581 --> 00:26:12,216 DIFFERENT DISCIPLINES TOGETHER 756 00:26:12,216 --> 00:26:17,120 TO WORK FOR A NUMBER OF YEARS 757 00:26:17,120 --> 00:26:19,056 AND DEVELOP THE RESEARCH IN 758 00:26:19,056 --> 00:26:20,324 THOSE AREAS WAS THE WAY TO GO. 759 00:26:20,324 --> 00:26:22,059 SO WE ACTUALLY DEVELOPED THOSE 760 00:26:22,059 --> 00:26:23,260 RESEARCH NETWORKS. 761 00:26:23,260 --> 00:26:25,229 THIS IS AN INFRASTRUCTURE 762 00:26:25,229 --> 00:26:29,766 MECHANISM ACTUALLY THAT WOULD 763 00:26:29,766 --> 00:26:31,368 FACILITATE RESEARCH THROUGH 764 00:26:31,368 --> 00:26:34,004 CONFERENCE, MEETINGS, SMALL 765 00:26:34,004 --> 00:26:35,239 SCALE PILOT PROJECTS THAT WOULD 766 00:26:35,239 --> 00:26:36,406 ALLOW INVESTIGATORS TO BECOME 767 00:26:36,406 --> 00:26:40,344 MORE COMPETITIVE FOR REGULAR R0Y 768 00:26:40,344 --> 00:26:41,712 CROSS TRAINING. 769 00:26:41,712 --> 00:26:45,349 SO WORKSHOPS OF OUR INSTITUTE 770 00:26:45,349 --> 00:26:46,617 VISITING SCHOLARS PROGRAM TO 771 00:26:46,617 --> 00:26:47,818 INFORM THE DISSEMINATION AND THE 772 00:26:47,818 --> 00:26:50,220 GROWTH OF THAT FIELD. 773 00:26:50,220 --> 00:26:52,956 SO WE HAD KIND OF A TALL ORDER 774 00:26:52,956 --> 00:26:53,690 FOR THESE NETWORKS. 775 00:26:53,690 --> 00:26:56,360 WE WANTED THEM TO TACKLE SIX 776 00:26:56,360 --> 00:26:58,862 DIFFERENT PRIORITY AREAS: THE 777 00:26:58,862 --> 00:27:00,597 ONTOLOGY AND MEASUREMENT OF 778 00:27:00,597 --> 00:27:01,598 EMOTIONAL WELL-BEING, THE 779 00:27:01,598 --> 00:27:02,966 MECHANISTIC RESEARCH THAT'S 780 00:27:02,966 --> 00:27:06,870 NEEDED TO UNDERSTAND THE ROLE OF 781 00:27:06,870 --> 00:27:09,706 EWB IN HEALTH, DEVELOPMENT OF 782 00:27:09,706 --> 00:27:11,475 BIOMARKERS FOR EMOTIONAL 783 00:27:11,475 --> 00:27:13,877 WELL-BEING, ALSO SOME PREVENTION 784 00:27:13,877 --> 00:27:16,079 RESEARCH, TECHNOLOGY AND OUTCOME 785 00:27:16,079 --> 00:27:17,247 MEASURE DEVELOPMENT, AND OF 786 00:27:17,247 --> 00:27:18,982 COURSE DEVELOPMENT AND 787 00:27:18,982 --> 00:27:19,883 VALIDATION OF WELL-BEING 788 00:27:19,883 --> 00:27:24,688 MEASURES. 789 00:27:24,688 --> 00:27:29,626 SO IN 2021, NICCH, NICHD, NIA, 790 00:27:29,626 --> 00:27:31,728 AND THE OFFICE OF BEHAVIORAL AND 791 00:27:31,728 --> 00:27:34,298 SOCIAL SCIENCE RESEARCH IN THE 792 00:27:34,298 --> 00:27:36,400 OFFICE OF DISEASE PREVENTION 793 00:27:36,400 --> 00:27:38,402 FUNDED SIX NETWORKS. 794 00:27:38,402 --> 00:27:40,537 AND WE WERE REALLY ENCOURAGED TO 795 00:27:40,537 --> 00:27:44,775 SEE THE BREADTH OF CONTENT OF 796 00:27:44,775 --> 00:27:47,210 THOSE -- THE INTEREST IN THESE 797 00:27:47,210 --> 00:27:48,645 NETWORKS AND ALSO THE GEOGRAPHIC 798 00:27:48,645 --> 00:27:49,079 DIVERSITY. 799 00:27:49,079 --> 00:27:52,482 SO WE HAVE UNIVERSITY OF ALABAMA 800 00:27:52,482 --> 00:27:54,117 IN BIRMINGHAM FOCUSING ON 801 00:27:54,117 --> 00:27:55,819 EMOTIONAL WELL-BEING AND THE 802 00:27:55,819 --> 00:27:57,087 ECONOMIC BURDEN. 803 00:27:57,087 --> 00:28:00,257 WE HAVE UNIVERSITY OF 804 00:28:00,257 --> 00:28:02,592 CONNECTICUT STUDYING THE 805 00:28:02,592 --> 00:28:05,062 MECHANISMS UNDERLYING MIND-BODY 806 00:28:05,062 --> 00:28:07,030 INTERVENTIONS AND THE 807 00:28:07,030 --> 00:28:10,400 MEASUREMENT OF EMOTIONAL 808 00:28:10,400 --> 00:28:11,168 WELL-BEING, UNIVERSITY OF 809 00:28:11,168 --> 00:28:12,703 WISCONSIN-MADISON, THE PL 810 00:28:12,703 --> 00:28:13,704 PLASTICITY OF WELL-BEING, THE 811 00:28:13,704 --> 00:28:15,973 NETWORK REALLY WANTS TO DEFINE 812 00:28:15,973 --> 00:28:18,075 MEASURES, ALL THE ASPECTS OF 813 00:28:18,075 --> 00:28:18,909 HUMAN FLOURISHING. 814 00:28:18,909 --> 00:28:21,678 WE HAVE UNIVERSITY OF CALIFORNIA 815 00:28:21,678 --> 00:28:22,846 SAN FRANCISCO LOOKING AT THE 816 00:28:22,846 --> 00:28:24,281 PSYCHOSOCIAL AND BIOBEHAVIORAL 817 00:28:24,281 --> 00:28:28,418 APPROACHES TO IMPROVE WELL-B 818 00:28:28,418 --> 00:28:28,719 WELL-BEING. 819 00:28:28,719 --> 00:28:31,321 THE BRAIN IMAGING NETWORK THAT 820 00:28:31,321 --> 00:28:33,790 DR. KELLEY MENTIONS IN NEW YORK, 821 00:28:33,790 --> 00:28:35,559 UNIVERSITY OF ROCHESTER. 822 00:28:35,559 --> 00:28:36,860 AND THEN FAMILY WELL-BEING, 823 00:28:36,860 --> 00:28:38,495 WHICH IS THE UNIVERSITY OF 824 00:28:38,495 --> 00:28:40,130 MICHIGAN, THAT'S FUNDED BY 825 00:28:40,130 --> 00:28:40,497 NICHD. 826 00:28:40,497 --> 00:28:42,699 SO AS YOU CAN SEE, WE HAD KIND 827 00:28:42,699 --> 00:28:45,836 OF A REALLY -- A BREADTH OF 828 00:28:45,836 --> 00:28:48,472 VARIOUS INTERESTS, AND IT'S ALL 829 00:28:48,472 --> 00:28:49,473 ACROSS THE COUNTRY. 830 00:28:49,473 --> 00:28:51,108 SO WE WERE VERY PLEASED WITH 831 00:28:51,108 --> 00:28:55,245 THAT OUTCOME. 832 00:28:55,245 --> 00:28:57,180 SO ALL ALONG, THESE NETWORKS, 833 00:28:57,180 --> 00:28:58,415 THE PRIMARY GOAL WAS TO REALLY 834 00:28:58,415 --> 00:29:00,684 GROW A COMMUNITY THAT WOULD BE 835 00:29:00,684 --> 00:29:04,588 ABLE TO DEVELOP THE RESEARCH 836 00:29:04,588 --> 00:29:05,756 THAT WOULD FILL THOSE GAPS THAT 837 00:29:05,756 --> 00:29:09,259 WE DIDN'T HAVE IN THE CONTEXT OF 838 00:29:09,259 --> 00:29:11,328 UNDERSTANDING WELL-BEING IN 839 00:29:11,328 --> 00:29:12,896 GENERAL, AND HOW IT INTERSECTS 840 00:29:12,896 --> 00:29:17,034 WITH HEALTH. 841 00:29:17,034 --> 00:29:18,969 SO AS YOU CAN SEE ON THIS SLIDE, 842 00:29:18,969 --> 00:29:20,637 AT THE BEGINNING, THE NUMBER OF 843 00:29:20,637 --> 00:29:22,406 MEMBERS FOR EACH OF THE 844 00:29:22,406 --> 00:29:23,940 NETWORKS, THIS STARTED SMALL, 845 00:29:23,940 --> 00:29:26,309 BUT IN THE PAST THREE YEARS, I'M 846 00:29:26,309 --> 00:29:30,313 PLEASED TO SEE THAT WE HAVE 847 00:29:30,313 --> 00:29:32,215 QUITE A STEADY GROWTH IN THE 848 00:29:32,215 --> 00:29:33,884 NUMBER OF MEMBERS IN THOSE 849 00:29:33,884 --> 00:29:34,151 NETWORKS. 850 00:29:34,151 --> 00:29:36,787 THIS IS THE BEAUTY OF USING THIS 851 00:29:36,787 --> 00:29:39,189 INFRASTRUCTURE MECHANISM, IS 852 00:29:39,189 --> 00:29:41,525 THAT WHILE YOU HAVE A CORSET OF 853 00:29:41,525 --> 00:29:42,926 INVESTIGATORS IN EACH OF THOSE 854 00:29:42,926 --> 00:29:45,695 FUNDED NETWORKS, THE ABILITY TO 855 00:29:45,695 --> 00:29:48,832 BRING NEW PEOPLE FROM VARIOUS 856 00:29:48,832 --> 00:29:50,934 FIELDS TO JOIN THE NETWORK TO 857 00:29:50,934 --> 00:29:53,336 ACTUALLY BRING THEIR EXPERTISE, 858 00:29:53,336 --> 00:29:54,538 DEVELOP PILOT PROJECTS THAT 859 00:29:54,538 --> 00:29:57,407 WOULD ACTUALLY ENRICH THE 860 00:29:57,407 --> 00:29:58,708 RESEARCH HAS BEEN TREMENDOUS. 861 00:29:58,708 --> 00:30:01,812 AND AS YOU CAN SEE, THE NUMBERS 862 00:30:01,812 --> 00:30:04,514 ARE LOOKING VERY, VERY GOOD, AND 863 00:30:04,514 --> 00:30:06,383 THE GROUP STILL HAS ONE YEAR TO 864 00:30:06,383 --> 00:30:06,750 GO. 865 00:30:06,750 --> 00:30:10,120 AND OF COURSE, THE IMPORTANCE OF 866 00:30:10,120 --> 00:30:12,155 BRINGING YOUNGER INVESTIGATORS 867 00:30:12,155 --> 00:30:15,358 INTO THE FIELD HAS BEEN REALLY 868 00:30:15,358 --> 00:30:16,760 VERY ENCOURAGING AS WELL, AS YOU 869 00:30:16,760 --> 00:30:19,596 CAN SEE THE NUMBERS OF TRAINEES 870 00:30:19,596 --> 00:30:20,931 THAT ARE PARTICIPATING IN EACH 871 00:30:20,931 --> 00:30:24,201 OF THE NETWORKS HAS BEEN REALLY 872 00:30:24,201 --> 00:30:24,768 GROWING STEADILY. 873 00:30:24,768 --> 00:30:26,269 SO WE'RE VERY PLEASED WITH THAT 874 00:30:26,269 --> 00:30:30,140 ASPECT. 875 00:30:30,140 --> 00:30:32,542 DR. KELLEY MENTIONED SOME OF THE 876 00:30:32,542 --> 00:30:35,278 PUBLICATIONS THAT HAVE COME OUT 877 00:30:35,278 --> 00:30:36,480 FROM THE INVESTIGATORS THAT ARE 878 00:30:36,480 --> 00:30:39,316 INVOLVED IN THOSE NETWORKS. 879 00:30:39,316 --> 00:30:42,752 TO DATE, WE HAVE ABOUT 51 880 00:30:42,752 --> 00:30:44,721 PUBLICATIONS HIGHLIGHTED HERE A 881 00:30:44,721 --> 00:30:46,189 COUPLE OF THEM. 882 00:30:46,189 --> 00:30:48,158 DR. KELLEY ALREADY MENTIONED THE 883 00:30:48,158 --> 00:30:51,194 PUBLICATION FROM DR. PARK AND 884 00:30:51,194 --> 00:30:54,831 THE GROUP, THE ONTOLOGY GROUP ON 885 00:30:54,831 --> 00:30:56,333 EMOTIONAL WELL-BEING, WHAT IS IT 886 00:30:56,333 --> 00:30:59,970 AND WHY IT MATTERS, AND THIS WAS 887 00:30:59,970 --> 00:31:01,505 REALLY -- AND THAT FOLLOWED WITH 888 00:31:01,505 --> 00:31:05,008 A NUMBER OF OPINION PIECES FROM 889 00:31:05,008 --> 00:31:06,877 THE COMMUNITY AND ALSO FROM THE 890 00:31:06,877 --> 00:31:07,777 NIH. 891 00:31:07,777 --> 00:31:11,047 AND SO I THINK WE ARE 892 00:31:11,047 --> 00:31:12,649 ACCOMPLISHING THE GOAL IN 893 00:31:12,649 --> 00:31:15,418 STIMULATING INTERESTS AND 894 00:31:15,418 --> 00:31:16,086 SPARKING SOME CONTROVERSY, WHICH 895 00:31:16,086 --> 00:31:19,556 IS EXACTLY WHAT WE INTENDED TO 896 00:31:19,556 --> 00:31:20,924 HAVE, IS THAT REALLY HAVING 897 00:31:20,924 --> 00:31:23,226 PEOPLE TALK ABOUT THE WHOLE 898 00:31:23,226 --> 00:31:24,694 CONCEPT OF EMOTIONAL WELL-BEING 899 00:31:24,694 --> 00:31:26,663 AND WHAT IT MEANS. 900 00:31:26,663 --> 00:31:29,432 THERE'S ALSO A NUMBER OF SCOPING 901 00:31:29,432 --> 00:31:30,800 REVIEWS LOOKING AT VARIOUS 902 00:31:30,800 --> 00:31:34,004 ASPECTS OF EMOTIONAL WELL-BEING. 903 00:31:34,004 --> 00:31:40,177 AND OF COURSE FROM A PAPER FOCG 904 00:31:40,177 --> 00:31:43,547 ON THE IMPACT OF FINANCIAL 905 00:31:43,547 --> 00:31:48,418 HARDSHIP ON EMOTIONAL WELL-BEING 906 00:31:48,418 --> 00:31:49,452 WELL-BEING. 907 00:31:49,452 --> 00:31:50,654 A NUMBER OF CONFERENCES ALSO 908 00:31:50,654 --> 00:31:52,455 HAVE BEEN INCREASING. 909 00:31:52,455 --> 00:31:53,990 HIGHLIGHTED HERE, A COUPLE OF 910 00:31:53,990 --> 00:31:54,424 THEM. 911 00:31:54,424 --> 00:31:59,062 LAST YEAR, AT THE APS, WE HAD A 912 00:31:59,062 --> 00:32:02,766 LOVELY SYMPOSIUM ON EMOTIONAL 913 00:32:02,766 --> 00:32:03,967 WELL-BEING, CAN WE MEASURE IT, 914 00:32:03,967 --> 00:32:06,236 CAN WE MONITOR IT, AND CAN WE 915 00:32:06,236 --> 00:32:07,804 MODULATE IT IN THE BRAIN, AND 916 00:32:07,804 --> 00:32:12,142 THAT WAS REALLY WELL RECEIVED BY 917 00:32:12,142 --> 00:32:14,678 THE APS COMMUNITY. 918 00:32:14,678 --> 00:32:18,081 AND VERY, VERY EXCITED, IF YOU 919 00:32:18,081 --> 00:32:20,350 COME TO THE SOCIETY FOR 920 00:32:20,350 --> 00:32:23,186 NEUROSCIENCE IN 2024, WE 921 00:32:23,186 --> 00:32:25,722 ACTUALLY HAVE -- WE WILL HAVE AN 922 00:32:25,722 --> 00:32:27,324 EMOTIONAL WELL-BEING SYMPOSIUM 923 00:32:27,324 --> 00:32:30,961 AT SFN, FOCUSING ON THE HEALTH 924 00:32:30,961 --> 00:32:34,231 IMPACT AND THE NEURAL INSIGHTS 925 00:32:34,231 --> 00:32:39,603 THAT THE NETWORK INVESTIGATORS 926 00:32:39,603 --> 00:32:40,737 HAVE BEEN GAINING. 927 00:32:40,737 --> 00:32:42,072 REALLY IMPORTANT, THE NETWORKS 928 00:32:42,072 --> 00:32:48,011 WERE FUNDED FOR FOUR YEARS, SO 929 00:32:48,011 --> 00:32:50,113 WITH THE INVESTMENT ON THE PILOT 930 00:32:50,113 --> 00:32:52,849 PROJECT, THE IDEA WAS THAT THE 931 00:32:52,849 --> 00:32:55,218 INVESTIGATORS AND THE P.I.s 932 00:32:55,218 --> 00:32:58,021 FROM THOSE PILOT PROJECTS WILL 933 00:32:58,021 --> 00:32:59,189 BE GENERATING PRELIMINARY DATA 934 00:32:59,189 --> 00:33:00,223 THAT WOULD ALLOW THEM TO 935 00:33:00,223 --> 00:33:03,893 CONTINUE THEIR RESEARCH THROUGH 936 00:33:03,893 --> 00:33:05,328 R01 MECHANISM OR OTHER 937 00:33:05,328 --> 00:33:07,197 INITIATIVES THAT ARE ONGOING AT 938 00:33:07,197 --> 00:33:08,298 THE NIH. 939 00:33:08,298 --> 00:33:09,432 AND CURRENTLY THERE ARE A NUMBER 940 00:33:09,432 --> 00:33:12,402 OF ACTIVITIES THAT ARE VERY WELL 941 00:33:12,402 --> 00:33:15,972 ALIGNED WITH THE CONCEPT OF 942 00:33:15,972 --> 00:33:18,508 EMOTIONAL WELL-BEING AND OTHER 943 00:33:18,508 --> 00:33:20,343 PROJECTS AND OTHER NEW 944 00:33:20,343 --> 00:33:21,411 DIRECTIONS. 945 00:33:21,411 --> 00:33:25,815 SO NICCH, NIA AND A NUMBER OF 946 00:33:25,815 --> 00:33:27,550 OTHER -- NICHD, A NUMBER OF 947 00:33:27,550 --> 00:33:28,785 OTHER INSTITUTES, HAVE BEEN PART 948 00:33:28,785 --> 00:33:31,588 OF A TRANS-NIH RESILIENCE 949 00:33:31,588 --> 00:33:32,889 WORKING GROUP, AND THAT GROUP 950 00:33:32,889 --> 00:33:38,695 HAS BEEN REALLY DEVELOPING THE 951 00:33:38,695 --> 00:33:40,563 COMMON RESILIENCE DEFINITION AND 952 00:33:40,563 --> 00:33:41,264 CONCEPTUAL FRAMEWORK. 953 00:33:41,264 --> 00:33:42,632 A NUMBER OF PAPERS HAVE BEEN 954 00:33:42,632 --> 00:33:44,034 PUBLISHED LAST YEAR, AND 955 00:33:44,034 --> 00:33:46,636 CURRENTLY THERE'S GOING TO BE A 956 00:33:46,636 --> 00:33:49,572 CONFERENCE IN SEPTEMBER OF 2024 957 00:33:49,572 --> 00:33:51,775 ABOUT THE METRICS OF RESILIENCE. 958 00:33:51,775 --> 00:33:56,513 SO THERE IS DEFINITELY AN 959 00:33:56,513 --> 00:33:57,981 INTERFACE BETWEEN WELL-BEING AND 960 00:33:57,981 --> 00:33:58,448 RESILIENCE. 961 00:33:58,448 --> 00:34:01,618 SO THAT WILL BE AN AREA -- A 962 00:34:01,618 --> 00:34:04,120 POTENTIAL AREA OF DEVELOPMENT 963 00:34:04,120 --> 00:34:07,190 FOR THE INVESTIGATORS OF THE 964 00:34:07,190 --> 00:34:08,892 NETWORKS. 965 00:34:08,892 --> 00:34:12,529 ANOTHER LARGE SCALE INITIATIVE 966 00:34:12,529 --> 00:34:13,963 IS THE TRANS-NIH BRAIN 967 00:34:13,963 --> 00:34:18,668 INITIATIVE THAT HAS BEEN FUNDED 968 00:34:18,668 --> 00:34:20,437 BY THE NIH DIRECTOR'S OFFICE. 969 00:34:20,437 --> 00:34:22,172 AND EE SESSIONALLY, THERE IS A 970 00:34:22,172 --> 00:34:24,941 PARTICULAR INITIATIVE THAT'S 971 00:34:24,941 --> 00:34:27,177 CALLED THE BBQS PROGRAM, WHICH 972 00:34:27,177 --> 00:34:29,279 IS BRAIN BEHAVIORAL 973 00:34:29,279 --> 00:34:31,381 QUANTIFICATION AND 974 00:34:31,381 --> 00:34:31,948 SYNCHRONIZATION. 975 00:34:31,948 --> 00:34:33,717 THERE'S A NUMBER OF ACTIVITIES 976 00:34:33,717 --> 00:34:34,651 THERE, FUNDING OPPORTUNITIES, 977 00:34:34,651 --> 00:34:39,756 THAT WOULD BE VERY WELL ALIGNED 978 00:34:39,756 --> 00:34:45,228 WITH EMOTIONAL WELL-BEING. 979 00:34:45,228 --> 00:34:48,098 THERE IS ALSO NICCH AND A NUMBER 980 00:34:48,098 --> 00:34:49,999 OF NIH INSTITUTES A FEW YEARS 981 00:34:49,999 --> 00:34:53,603 AGO HAD DONE A NATIONAL ACADEMY 982 00:34:53,603 --> 00:34:57,774 OF SCIENCE STUDY FOCUSED ON 983 00:34:57,774 --> 00:35:00,777 FOSTERING MENTAL, EMOTIONAL, AND 984 00:35:00,777 --> 00:35:01,745 BEHAVIORAL HEALTH AMONG CHILDREN 985 00:35:01,745 --> 00:35:04,280 IN SCHOOL SETTINGS. 986 00:35:04,280 --> 00:35:07,817 AND FOLLOWING THAT EVENT, THIS 987 00:35:07,817 --> 00:35:09,753 PARTICULAR REPORT, NICCH AND A 988 00:35:09,753 --> 00:35:11,755 NUMBER OF OTHER INSTITUTES 989 00:35:11,755 --> 00:35:15,458 ACTUALLY HAD AN INITIATIVE 990 00:35:15,458 --> 00:35:19,496 FOCUSED ON THAT COPY: CURRENTLY 991 00:35:19,496 --> 00:35:23,566 NICCH IS FUNDING THREE OF THOSE 992 00:35:23,566 --> 00:35:27,604 LARGE SCALE INTERVENTION ASK YOU 993 00:35:27,604 --> 00:35:34,511 INTER -- IN AREAS OFUNDERSERVED. 994 00:35:34,511 --> 00:35:36,079 SO THIS IS AN AREA OF INTEREST 995 00:35:36,079 --> 00:35:36,980 AND INVESTIGATORS FROM THE 996 00:35:36,980 --> 00:35:38,748 NETWORK CERTAINLY COULD MOVE 997 00:35:38,748 --> 00:35:40,283 INTO THAT DIRECTION. 998 00:35:40,283 --> 00:35:43,119 AND FINALLY, THERE HAS BEEN 999 00:35:43,119 --> 00:35:46,856 MOVEMENT AT THE NIH REALLY 1000 00:35:46,856 --> 00:35:49,993 LOOKING AT MU SIX MUSIC AND OTT 1001 00:35:49,993 --> 00:35:51,661 FORMS IN THE CONTEXT OF IMPACT 1002 00:35:51,661 --> 00:35:58,101 ON HEALTH, AND SO FOR US, MUSIC 1003 00:35:58,101 --> 00:36:06,776 ANHAS BEEN PART OF INVESTIGATORS 1004 00:36:06,776 --> 00:36:07,744 OF THE NETWORK TO MOVE THEIR 1005 00:36:07,744 --> 00:36:09,045 RESEARCH INTO THAT ARENA. 1006 00:36:09,045 --> 00:36:13,116 SO WE SEE THE FUTURE AS BRIGHT 1007 00:36:13,116 --> 00:36:18,288 FOR THIS GROUP, AS THE NETWORK 1008 00:36:18,288 --> 00:36:19,789 ACTUALLY COMPLETING THEIR FOURTH 1009 00:36:19,789 --> 00:36:22,325 YEAR, THERE WILL BE A LOT OF 1010 00:36:22,325 --> 00:36:27,764 OPPORTUNITIES THAT HAVE RELATED 1011 00:36:27,764 --> 00:36:29,866 SCIENTIFIC DIRECTION THAT THEY 1012 00:36:29,866 --> 00:36:32,802 CAN MOVE THEIR RESEARCH INTO. 1013 00:36:32,802 --> 00:36:34,471 SO WE'RE VERY, VERY PLEASED WITH 1014 00:36:34,471 --> 00:36:38,508 THE DIRECTION OF THOSE SIX 1015 00:36:38,508 --> 00:36:40,243 NETWORKS, AND NOW I'M GOING TO 1016 00:36:40,243 --> 00:36:45,715 TURN IT OVER TO DR. QUINLAN. 1017 00:36:45,715 --> 00:36:48,184 THANK YOU VERY MUCH. 1018 00:36:48,184 --> 00:36:54,257 [APPLAUSE] 1019 00:36:54,257 --> 00:36:54,457 ERIN? 1020 00:36:54,457 --> 00:36:55,692 >> GREAT. 1021 00:36:55,692 --> 00:36:59,462 >> I'M GOING TO STOP SHARING. 1022 00:36:59,462 --> 00:37:00,530 >> THANK YOU VERY MUCH, 1023 00:37:00,530 --> 00:37:00,864 EMMELINE. 1024 00:37:00,864 --> 00:37:02,265 THANK YOU FOR THAT GREAT 1025 00:37:02,265 --> 00:37:04,634 OVERVIEW OF SORT OF THE ORIGINS 1026 00:37:04,634 --> 00:37:05,735 OF EMOTIONAL WELL-BEING NETWORKS 1027 00:37:05,735 --> 00:37:07,203 AND ALSO FOR YOUR LEADERSHIP IN 1028 00:37:07,203 --> 00:37:08,605 THE GENERATION OF THE EMOTIONAL 1029 00:37:08,605 --> 00:37:10,440 WELL-BEING INITIATIVE THAT HAS 1030 00:37:10,440 --> 00:37:13,409 FUNDED THE SIX U24 NETWORKS. 1031 00:37:13,409 --> 00:37:15,178 SO NEXT WE'LL BEGIN THE 1032 00:37:15,178 --> 00:37:15,712 SUBSEQUENT PORTION OF THE 1033 00:37:15,712 --> 00:37:17,780 MEETING WHERE THE SIX NIH FUNDED 1034 00:37:17,780 --> 00:37:18,815 EMOTIONAL BEING NETWORKS THAT 1035 00:37:18,815 --> 00:37:20,316 YOU'VE STARTED TO HEAR ABOUT 1036 00:37:20,316 --> 00:37:21,851 WILL EACH HAVE 10 MINUTES TO 1037 00:37:21,851 --> 00:37:23,720 SHARE THEIR GOALS AND HIGHLIGHT 1038 00:37:23,720 --> 00:37:25,555 SOME OF THEIR ACCOMPLISHMENTS. 1039 00:37:25,555 --> 00:37:27,590 SO THOSE OF YOU IN THE VIDEOCAST 1040 00:37:27,590 --> 00:37:28,758 AUDIENCE, PLEASE DON'T FORGET TO 1041 00:37:28,758 --> 00:37:30,960 SUBMIT QUESTIONS AS WE WILL HAVE 1042 00:37:30,960 --> 00:37:33,263 A Q & A SESSION FOLLOWING THE 1043 00:37:33,263 --> 00:37:36,533 SIX 10-MINUTE PAREN TAIGS. 1044 00:37:36,533 --> 00:37:37,166 PRESENTATIONS. 1045 00:37:37,166 --> 00:37:39,602 I'D LIKE TO INVITE DR. RICHIE 1046 00:37:39,602 --> 00:37:49,779 DAVIDSON. 1047 00:38:32,455 --> 00:38:35,525 >> WHILE WE'RE WAITING FOR THIS, 1048 00:38:35,525 --> 00:38:36,893 LET ME JUST SAY THAT AS A NOTE 1049 00:38:36,893 --> 00:38:40,463 OF PERSONAL REFLECTION, I WAS 1050 00:38:40,463 --> 00:38:46,469 CO-CHAIR WITH BRUCE MCCUNE IN 1051 00:38:46,469 --> 00:38:48,671 2018 OF THE INITIATIVE WHICH LED 1052 00:38:48,671 --> 00:38:51,307 TO THE DEVELOPMENT OF THESE 1053 00:38:51,307 --> 00:38:52,909 NETWORKS, AND IT'S JUST REALLY 1054 00:38:52,909 --> 00:38:55,745 HEARTENING TO SEE HOW MUCH HAS 1055 00:38:55,745 --> 00:38:58,514 BEEN ACCOMPLISHED OVER THIS 1056 00:38:58,514 --> 00:38:59,248 RELATIVELY SHORT PERIOD OF TIME, 1057 00:38:59,248 --> 00:39:02,051 AND I THINK IF BRUCE WAS STILL 1058 00:39:02,051 --> 00:39:05,655 ALIVE WITH US TODAY, HE WOULD 1059 00:39:05,655 --> 00:39:08,591 REALLY BE QUITE PLEASED TO SEE 1060 00:39:08,591 --> 00:39:09,559 WHAT HAS BEEN ACCOMPLISHED IN 1061 00:39:09,559 --> 00:39:17,367 THIS TIME. 1062 00:39:17,367 --> 00:39:20,236 OKAY. 1063 00:39:20,236 --> 00:39:22,238 >> TECHNICAL DIFFICULTY. 1064 00:39:22,238 --> 00:39:24,073 WE WILL GET THERE ONE SLIDE AT A 1065 00:39:24,073 --> 00:39:34,384 TIME IF NECESSARY. 1066 00:39:41,290 --> 00:39:42,625 THANK YOU FOR YOUR PATIENCE. 1067 00:39:42,625 --> 00:39:43,426 THANK YOU, RICHIE. 1068 00:39:43,426 --> 00:39:44,227 >> THANK YOU. 1069 00:39:44,227 --> 00:39:45,561 SO IT'S GREAT TO BE HERE AND TO 1070 00:39:45,561 --> 00:39:47,597 GIVE YOU A LITTLE UPDATE ON OUR 1071 00:39:47,597 --> 00:39:50,366 NETWORK ON THE PLASTICITY OF 1072 00:39:50,366 --> 00:39:51,701 WELL-BEING. 1073 00:39:51,701 --> 00:39:55,471 WE HAVE COME TO THIS IDEA OF THE 1074 00:39:55,471 --> 00:39:57,040 PLASTICITY OF WELL-BEING IN WAYS 1075 00:39:57,040 --> 00:39:58,941 THAT WE LIKEN TO CLIMATE 1076 00:39:58,941 --> 00:40:01,644 SCIENTISTS WHO BELIEVE THAT THE 1077 00:40:01,644 --> 00:40:05,181 EVIDENCE FOR THE NEWER TOURING 1078 00:40:05,181 --> 00:40:07,550 OF WELL-BEING IS SUFFICIENTLY 1079 00:40:07,550 --> 00:40:11,721 COMPELLING THAT WE NEED TO ACT 1080 00:40:11,721 --> 00:40:15,858 AND SO OUR FOCUS HAS REALLY BEEN 1081 00:40:15,858 --> 00:40:18,628 ON WAYS TO CULTIVATE AND NURTURE 1082 00:40:18,628 --> 00:40:22,632 DIFFERENT COMPONENTS OF 1083 00:40:22,632 --> 00:40:25,435 WELL-BEING AND TO STUDY HOW 1084 00:40:25,435 --> 00:40:29,205 THOSE INTERVENTIONS ARE 1085 00:40:29,205 --> 00:40:31,941 AFFECTING THE PSYCHOLOGICAL AND 1086 00:40:31,941 --> 00:40:33,076 BIOLOGICAL CORRELATES AND 1087 00:40:33,076 --> 00:40:34,444 MEDIATORS OF WELL-BEING. 1088 00:40:34,444 --> 00:40:36,879 ONE OF THE OTHER INTENTIONS IN 1089 00:40:36,879 --> 00:40:39,615 CREATING THIS NETWORK WAS ALSO 1090 00:40:39,615 --> 00:40:41,984 TO BE INTERDISCIPLINARY AND 1091 00:40:41,984 --> 00:40:44,954 BRING SCIENTISTS WHO HAVE NOT 1092 00:40:44,954 --> 00:40:46,689 PREVIOUSLY BEEN INVOLVED IN THE 1093 00:40:46,689 --> 00:40:48,858 STUDY OF WELL-BEING, IN FACT, 1094 00:40:48,858 --> 00:40:50,860 WHO'VE NOT BEEN INVOLVED IN 1095 00:40:50,860 --> 00:40:52,729 BEHAVIORAL OR BIOBEHAVIORAL 1096 00:40:52,729 --> 00:40:55,465 SCIENCE AT ALL PRETTY MUCH TO 1097 00:40:55,465 --> 00:40:57,600 THE TABLE, WHOSE EXPERTISE CAN 1098 00:40:57,600 --> 00:40:58,868 REALLY BE VERY RELEVANT. 1099 00:40:58,868 --> 00:41:01,704 SO WE HAVE ONE OF THE WORLD'S 1100 00:41:01,704 --> 00:41:03,639 LEADING EXPERTS IN THE 1101 00:41:03,639 --> 00:41:04,941 MICROBIOME WHO'S PART OF OUR 1102 00:41:04,941 --> 00:41:07,243 NETWORK, WE HAVE A COMPUTER 1103 00:41:07,243 --> 00:41:10,646 SCIENTIST AT MIT WHO IS AN 1104 00:41:10,646 --> 00:41:13,282 EXPERT IN COMPUTER VISION AND 1105 00:41:13,282 --> 00:41:16,652 MACHINE LEARNING, AND WE ALSO 1106 00:41:16,652 --> 00:41:18,755 HAVE A BIOLOGICAL ANTHROPOLOGIST 1107 00:41:18,755 --> 00:41:21,057 WHO'S BEEN A PIONEER IN THE 1108 00:41:21,057 --> 00:41:23,993 DEVELOPMENT OF NOVEL BIOLOGICAL 1109 00:41:23,993 --> 00:41:25,261 MEASURES THAT CAN BE USED IN THE 1110 00:41:25,261 --> 00:41:26,529 FIELD. 1111 00:41:26,529 --> 00:41:28,197 AND I'LL MENTION THESE AS WE GO 1112 00:41:28,197 --> 00:41:29,365 ALONG. 1113 00:41:29,365 --> 00:41:31,367 SO THE OVERALL GOALS IN THE 1114 00:41:31,367 --> 00:41:33,669 NETWORK WERE TO CONVENE THIS 1115 00:41:33,669 --> 00:41:36,672 MULTIDISCIPLINARY FACULTY WITH 1116 00:41:36,672 --> 00:41:40,143 UNIQUE AND COMPLEMENTARY 1117 00:41:40,143 --> 00:41:42,445 EXPERTISE TO ADVANCE BOTH THE 1118 00:41:42,445 --> 00:41:44,413 MEASUREMENT OF -- FOCUS ON THE 1119 00:41:44,413 --> 00:41:45,114 MEASUREMENT OF WELL-BEING AS 1120 00:41:45,114 --> 00:41:46,616 WELL AS ON CULTIVATING 1121 00:41:46,616 --> 00:41:48,351 WELL-BEING. 1122 00:41:48,351 --> 00:41:51,220 WE ALSO HAVE BEEN AWARDING PILOT 1123 00:41:51,220 --> 00:41:53,523 PROJECT FUNDING FOR NOVEL 1124 00:41:53,523 --> 00:41:54,257 RESEARCH. 1125 00:41:54,257 --> 00:41:56,359 WE HAVE FUNDED AND SUPPORTED 1126 00:41:56,359 --> 00:41:59,762 COMMUNITY ENGAGED RESEARCH THAT 1127 00:41:59,762 --> 00:42:02,064 PRIORITIZES EMOTIONAL HEALTH 1128 00:42:02,064 --> 00:42:04,233 EQUITY, AND YOU'LL HEAR ABOUT 1129 00:42:04,233 --> 00:42:08,738 THAT FROM TR CHRISTIE, WHOLE I'L 1130 00:42:08,738 --> 00:42:10,273 INTRODUCE IN A MOMENT AND ALSO 1131 00:42:10,273 --> 00:42:12,275 SUPPORTING EMERGING EARLY CAREER 1132 00:42:12,275 --> 00:42:13,276 SCHOLARS IN LEARNING ABOUT 1133 00:42:13,276 --> 00:42:15,444 RESEARCH IN THIS AREA, INFORMING 1134 00:42:15,444 --> 00:42:16,779 COLLABORATIONS AND REALLY IN 1135 00:42:16,779 --> 00:42:20,650 HELPING TO NURTURE THIS NASCENT 1136 00:42:20,650 --> 00:42:23,019 FIELD, AND NOT JUST PROVIDING 1137 00:42:23,019 --> 00:42:24,420 THE STANDARD INTELLECTUAL 1138 00:42:24,420 --> 00:42:25,788 FRAMEWORK BUT HOW CAN WE ALSO 1139 00:42:25,788 --> 00:42:28,691 WALK THE TALK, AND ACTUALLY 1140 00:42:28,691 --> 00:42:31,360 CREATE AN ENVIRONMENT WHERE 1141 00:42:31,360 --> 00:42:32,128 EMOTIONAL WELL-BEING CAN THRIVE 1142 00:42:32,128 --> 00:42:35,064 IN THE ACADEMY, SOMETHING THAT 1143 00:42:35,064 --> 00:42:36,199 DOESN'T HAPPEN ON A REGULAR 1144 00:42:36,199 --> 00:42:38,901 BASIS. 1145 00:42:38,901 --> 00:42:40,803 SO LET ME SAY A LITTLE BIT ABOUT 1146 00:42:40,803 --> 00:42:42,405 OUR KEY ACCOMPLISHMENTS. 1147 00:42:42,405 --> 00:42:44,540 WE'VE ALL COME TOGETHER IN A 1148 00:42:44,540 --> 00:42:46,509 LARGE COLLABORATIVE STUDY THAT 1149 00:42:46,509 --> 00:42:48,177 INVOLVES EVERY MEMBER OF THE 1150 00:42:48,177 --> 00:42:51,881 NETWORK IN VARIOUS AND DIFFERENT 1151 00:42:51,881 --> 00:42:55,084 WAYS, AND THIS STUDY HAS TAKEN 1152 00:42:55,084 --> 00:42:58,254 ADVANTAGE OF A FRAMEWORK THAT WE 1153 00:42:58,254 --> 00:42:59,555 HAVE PUBLISHED A COUPLE YEARS 1154 00:42:59,555 --> 00:43:01,290 AGO ON THE PLASTICITY OF 1155 00:43:01,290 --> 00:43:02,825 WELL-BEING THAT HOLDS THAT THERE 1156 00:43:02,825 --> 00:43:05,061 ARE THESE FOUR KEY PILLARS OF 1157 00:43:05,061 --> 00:43:06,462 WELL-BEING, EACH OF WHICH 1158 00:43:06,462 --> 00:43:08,698 EXHIBITS PLASTICITY. 1159 00:43:08,698 --> 00:43:12,068 THESE ARE LISTED HERE. 1160 00:43:12,068 --> 00:43:14,136 AWARENESS, WHICH WOULD INCLUDE 1161 00:43:14,136 --> 00:43:16,672 MINDFULNESS, CONNECTION, WHICH 1162 00:43:16,672 --> 00:43:17,340 INCLUDES QUALITIES THAT ARE 1163 00:43:17,340 --> 00:43:19,542 IMPORTANT FOR HEALTHY SOCIAL 1164 00:43:19,542 --> 00:43:21,510 RELATIONSHIPS, QUALITIES LIKE 1165 00:43:21,510 --> 00:43:22,879 APPRECIATION AND GRATITUDE AND 1166 00:43:22,879 --> 00:43:25,348 KINDNESS AND COMPASSION. 1167 00:43:25,348 --> 00:43:27,817 INSIGHT, WHICH IS INSIGHT INTO 1168 00:43:27,817 --> 00:43:30,519 THE NARRATIVE THAT WE ALL CARRY 1169 00:43:30,519 --> 00:43:32,188 AROUND ABOUT OURSELVES, OUR 1170 00:43:32,188 --> 00:43:34,156 BELIEFS AND EXPECTATIONS OF 1171 00:43:34,156 --> 00:43:34,590 OURSELVES. 1172 00:43:34,590 --> 00:43:37,660 AND FINALLY, PURPOSE. 1173 00:43:37,660 --> 00:43:41,063 AND YOU'LL NOTE THAT THIS 1174 00:43:41,063 --> 00:43:43,699 FRAMEWORK HAS TWO ELEMENTS THAT 1175 00:43:43,699 --> 00:43:45,568 ARE FOUND IN MOST OTHER FRAME 1176 00:43:45,568 --> 00:43:47,103 WORKS FOR UNDERSTANDING 1177 00:43:47,103 --> 00:43:48,404 WELL-BEING, AND THOSE ARE 1178 00:43:48,404 --> 00:43:49,872 CONNECTION AND PURPOSE, AND IT 1179 00:43:49,872 --> 00:43:52,074 HAS TWO ELEMENTS THAT, IN FACT, 1180 00:43:52,074 --> 00:43:54,210 AT LEAST IN OUR VIEW, ARE NOT 1181 00:43:54,210 --> 00:43:56,245 FOUND IN ANY OTHER FRAMEWORK. 1182 00:43:56,245 --> 00:43:59,048 AND THAT IS AWARENESS AND 1183 00:43:59,048 --> 00:44:00,082 INSIGHT. 1184 00:44:00,082 --> 00:44:02,485 AND FOR A VARIETY OF REASONS, WE 1185 00:44:02,485 --> 00:44:06,389 BELIEVE THAT THIS IS AN 1186 00:44:06,389 --> 00:44:07,390 IMPORTANT AND DIFFERENT 1187 00:44:07,390 --> 00:44:10,026 FRAMEWORK THAT HARNESSES THE 1188 00:44:10,026 --> 00:44:12,762 INSIGHTS GLEANED FROM BOTH 1189 00:44:12,762 --> 00:44:13,796 CONTEMPLATIVE TRADITIONS AS WELL 1190 00:44:13,796 --> 00:44:16,198 AS FROM MODERN SCIENCE. 1191 00:44:16,198 --> 00:44:18,367 WE HAVE DEVELOPED A CURRICULUM 1192 00:44:18,367 --> 00:44:20,703 FOR TEACHING EACH OF THESE FOUR 1193 00:44:20,703 --> 00:44:22,772 PILLARS OF WELL-BEING THAT 1194 00:44:22,772 --> 00:44:24,740 INCLUDES BOTH DECLARATIVE 1195 00:44:24,740 --> 00:44:26,275 LEARNING, LEARNING ABOUT THESE 1196 00:44:26,275 --> 00:44:28,344 PILLARS, BUT ALSO PROCEDURAL 1197 00:44:28,344 --> 00:44:29,612 LEARNING. 1198 00:44:29,612 --> 00:44:36,052 PRACTICE-BASED LEARNING THAT IS 1199 00:44:36,052 --> 00:44:36,986 INSTANTIATED THROUGH SKILL 1200 00:44:36,986 --> 00:44:39,155 DEVELOPMENT AND WE KNOW IS 1201 00:44:39,155 --> 00:44:40,122 ASSOCIATED WITH BRAINNET WORKS 1202 00:44:40,122 --> 00:44:41,557 THAT ARE DIFFERENT FROM 1203 00:44:41,557 --> 00:44:43,125 DECLARATIVE LEARNING. 1204 00:44:43,125 --> 00:44:45,628 WE'VE PUT THIS IN THE FORM OF AN 1205 00:44:45,628 --> 00:44:47,330 APP THAT, BY THE WAY, IS 1206 00:44:47,330 --> 00:44:49,198 PUBLICLY AVAILABLE AND IS 1207 00:44:49,198 --> 00:44:50,633 TOTALLY FREE, AND IT'S CALLED 1208 00:44:50,633 --> 00:44:54,704 THE HEALTHY MINDS PROGRAM, AND 1209 00:44:54,704 --> 00:44:55,705 "THE NEW YORK TIMES" WIRE CUTTER 1210 00:44:55,705 --> 00:44:57,306 ACTUALLY NAMED IT AS ONE OF THE 1211 00:44:57,306 --> 00:44:58,574 THREE BEST MEDITATION APPS FOR 1212 00:44:58,574 --> 00:44:59,909 THREE YEARS IN A ROW, AND IT'S 1213 00:44:59,909 --> 00:45:03,646 THE ONLY ONE THAT'S ACTUALLY 1214 00:45:03,646 --> 00:45:07,650 EVIDENCE-BASED. 1215 00:45:07,650 --> 00:45:08,951 WE HAVE BEEN INVOLVED IN THIS 1216 00:45:08,951 --> 00:45:11,354 LARGE SCALE COLLABORATIVE STUDY, 1217 00:45:11,354 --> 00:45:13,522 ALL OF OUR NETWORK MEMBERS, AND 1218 00:45:13,522 --> 00:45:15,024 THESE ARE SOME OF THE KEY 1219 00:45:15,024 --> 00:45:16,559 ELEMENTS OF THE STUDY. 1220 00:45:16,559 --> 00:45:18,627 WE BEGAN WITH 1170 PEOPLE 1221 00:45:18,627 --> 00:45:21,097 RECRUITED NATIONALLY FROM, I 1222 00:45:21,097 --> 00:45:23,265 THINK EVERY STATE IN THE UNITED 1223 00:45:23,265 --> 00:45:26,736 STATES. 1224 00:45:26,736 --> 00:45:28,170 AND THEY ARE RANDOMLY ASSIGNED 1225 00:45:28,170 --> 00:45:29,872 TO ONE OF THREE GROUPS: THE 1226 00:45:29,872 --> 00:45:31,140 HEALTHY MINDS PROGRAM IS ONE 1227 00:45:31,140 --> 00:45:32,942 GROUP, AND WE HAVE A -- WHAT I 1228 00:45:32,942 --> 00:45:35,111 THINK IS A REALLY BEAUTIFUL 1229 00:45:35,111 --> 00:45:35,544 ACTIVE CONTROL. 1230 00:45:35,544 --> 00:45:37,747 WE DEVELOPED A VERSION OF THE 1231 00:45:37,747 --> 00:45:40,182 HEALTHY MINDS PROGRAM WHERE THEY 1232 00:45:40,182 --> 00:45:44,453 LEARN ALL OF THE DIDACTIC 1233 00:45:44,453 --> 00:45:46,889 MATERIAL, BUT THERE'S NO 1234 00:45:46,889 --> 00:45:48,057 INSTRUCTION FOR PROCEDURAL 1235 00:45:48,057 --> 00:45:50,226 LEARNING, NO MEDITATION 1236 00:45:50,226 --> 00:45:50,659 PRACTICE. 1237 00:45:50,659 --> 00:45:55,865 BUT THEY ENGAGE WITH THE APP FOR 1238 00:45:55,865 --> 00:45:57,600 AS MUCH TIME AS THE HEALTHY 1239 00:45:57,600 --> 00:45:58,501 MINDS GROUP DOES. 1240 00:45:58,501 --> 00:45:59,668 THEN WE HAVE A TREATMENT AS 1241 00:45:59,668 --> 00:46:00,403 USUAL GROUP. 1242 00:46:00,403 --> 00:46:02,104 THESE ARE ALL PARTICIPANTS WITH 1243 00:46:02,104 --> 00:46:04,206 ELEVATED LEVELS OF DEPRESSIVE 1244 00:46:04,206 --> 00:46:07,510 SYMPTOMS AND ALL OF THESE 1245 00:46:07,510 --> 00:46:11,213 INDIVIDUALS ARE ACTUALLY 1246 00:46:11,213 --> 00:46:16,218 SCREENED AND DIAGNOSED WITH 1247 00:46:16,218 --> 00:46:17,686 SKSs, WHICH HELPS US WITH A 1248 00:46:17,686 --> 00:46:19,588 FORMAL DIAGNOSIS BUT ALSO 1249 00:46:19,588 --> 00:46:20,689 ENSURES US THAT THESE ARE REAL 1250 00:46:20,689 --> 00:46:22,725 PEOPLE BECAUSE THIS IS A FULLY 1251 00:46:22,725 --> 00:46:26,729 REMOTE STUDY BECAUSE ALL OF THE 1252 00:46:26,729 --> 00:46:27,930 SKDs ARE DOB WITH ZOOM 1253 00:46:27,930 --> 00:46:28,297 INTERVIEWS. 1254 00:46:28,297 --> 00:46:29,832 THE FOLLOW-UP DATA ARE NOT 1255 00:46:29,832 --> 00:46:30,433 COMPLETE YET. 1256 00:46:30,433 --> 00:46:32,234 THERE'S STILL 12% OF THE SAMPLE 1257 00:46:32,234 --> 00:46:33,602 THAT'S NOT BEEN INVITED BACK. 1258 00:46:33,602 --> 00:46:36,806 THOSE NUMBERS WILL GO UP. 1259 00:46:36,806 --> 00:46:39,208 BUT WE'VE HAD REMARKABLY HIGH 1260 00:46:39,208 --> 00:46:39,475 RETENTION. 1261 00:46:39,475 --> 00:46:41,644 IF YOU LOOK AT THE 4-WEEK DATA 1262 00:46:41,644 --> 00:46:44,713 JUST IMMEDIATELY POST-TEST, 1263 00:46:44,713 --> 00:46:46,048 THOSE DATA ARE COMPLETE AND YOU 1264 00:46:46,048 --> 00:46:49,652 CAN SEE WE'VE HAD RETENTION THAT 1265 00:46:49,652 --> 00:46:51,353 EXCEEDS 83% IN ALL THE GROUPS. 1266 00:46:51,353 --> 00:46:55,291 THESE ARE A PEEK AT THE EARLY 1267 00:46:55,291 --> 00:46:56,692 DATA AT IMMEDIATELY POST 1268 00:46:56,692 --> 00:46:57,359 INTERVENTION. 1269 00:46:57,359 --> 00:46:59,195 THE HEALTHY MINDS PROGRAM IS IN 1270 00:46:59,195 --> 00:47:00,429 GREEN, THE ACTIVE CONTROL IS IN 1271 00:47:00,429 --> 00:47:04,033 RED. 1272 00:47:04,033 --> 00:47:07,136 AND THE TREATMENT IS IN BLUE. 1273 00:47:07,136 --> 00:47:07,736 THE EMOTIONAL WELL-BEING 1274 00:47:07,736 --> 00:47:11,440 MEASURE, THIS IS TYLER 1275 00:47:11,440 --> 00:47:12,541 VANDERWHEELER'S FLEWISHING 1276 00:47:12,541 --> 00:47:17,012 MEASURE, AND THEN YOU SEE THE 1277 00:47:17,012 --> 00:47:19,215 PHQ FOR DEPRESSION SYMPTOMS, AND 1278 00:47:19,215 --> 00:47:21,484 YOU CAN SEE THAT THE HEALTHY 1279 00:47:21,484 --> 00:47:25,321 MINDS PROGRAM IS LEADING TO 1280 00:47:25,321 --> 00:47:29,158 INCREASED FLOURISHING AND LARGER 1281 00:47:29,158 --> 00:47:30,426 ARE DECREASES IN DEPRESSION THAN 1282 00:47:30,426 --> 00:47:31,927 THE OTHER GROUPS, BUT THE ACTIVE 1283 00:47:31,927 --> 00:47:33,462 CONTROL GROUP IS DOING PRETTY 1284 00:47:33,462 --> 00:47:37,099 WELL ALSO, WHICH IS NOT 1285 00:47:37,099 --> 00:47:37,833 UNEXPECTED, GIVEN THE NATURE OF 1286 00:47:37,833 --> 00:47:40,236 THIS GROUP. 1287 00:47:40,236 --> 00:47:41,904 WE ALSO, AS PART OF THE NETWORK, 1288 00:47:41,904 --> 00:47:46,509 ARE PIONEERING IN THESE VARIOUS 1289 00:47:46,509 --> 00:47:47,510 BIOLOGICAL MEASURES THAT ARE 1290 00:47:47,510 --> 00:47:50,045 BEING COLLECTED IN THE FIELD. 1291 00:47:50,045 --> 00:47:51,347 SO WE'RE COLLECTING DRIED 1292 00:47:51,347 --> 00:47:52,648 BLOODSPOTS FROM ALL OF THE 1293 00:47:52,648 --> 00:47:53,649 PARTICIPANTS, AND WE ARE LOOKING 1294 00:47:53,649 --> 00:47:57,286 AT VARIOUS PRO-INFLAMMATORY 1295 00:47:57,286 --> 00:47:57,820 CYTOKINES. 1296 00:47:57,820 --> 00:47:59,522 WE'RE ALSO ACTUALLY GETTING 1297 00:47:59,522 --> 00:48:01,690 EPIGENETIC DATA FROM THESE DRIED 1298 00:48:01,690 --> 00:48:02,024 BLOODSPOTS. 1299 00:48:02,024 --> 00:48:04,293 WE ALSO ARE GETTING STOOL 1300 00:48:04,293 --> 00:48:05,895 SAMPLES FROM ALL THE 1301 00:48:05,895 --> 00:48:07,229 PARTICIPANTS PRE AND POTATOES 1302 00:48:07,229 --> 00:48:09,431 AND LOOKING AT THE GUT 1303 00:48:09,431 --> 00:48:12,034 MICROBIOTA AND WE ACTUALLY HAVE 1304 00:48:12,034 --> 00:48:13,035 SOME TANTALIZING PRELIMINARY 1305 00:48:13,035 --> 00:48:14,203 DATA ON THAT WHICH I'M NOT GOING 1306 00:48:14,203 --> 00:48:20,242 TO SHOW YOU, AND WITH ROZ AT 1307 00:48:20,242 --> 00:48:21,510 MIT, WE'RE COLLECTING A VERSION 1308 00:48:21,510 --> 00:48:22,444 OF EXPERIENCE SAMPLING THAT'S 1309 00:48:22,444 --> 00:48:24,713 DONE BY VIDEO, AND WE HAVE TWO 1310 00:48:24,713 --> 00:48:28,684 DIFFERENT MEASURES, ONE WHERE 1311 00:48:28,684 --> 00:48:29,785 PARTICIPANTS ARE ACTUALLY SHOWN 1312 00:48:29,785 --> 00:48:32,588 A VERY SHORT VIDEO CLIP ON THEIR 1313 00:48:32,588 --> 00:48:35,558 PHONE, A CLIP OF BABIES 1314 00:48:35,558 --> 00:48:39,428 LAUGHING, AND WE'RE RECORDING 1315 00:48:39,428 --> 00:48:40,629 THE FACIAL BEHAVIOR IN RESPONSE 1316 00:48:40,629 --> 00:48:41,297 TO THE CLIP. 1317 00:48:41,297 --> 00:48:46,135 WE ALSO ASK THEM IN ANOTHER 1318 00:48:46,135 --> 00:48:46,802 COMPONENT AND EXPERIENCE 1319 00:48:46,802 --> 00:48:47,703 SAMPLING QUESTION, PLEASE TELL 1320 00:48:47,703 --> 00:48:49,872 US ABOUT AN EMOTIONAL 1321 00:48:49,872 --> 00:48:51,073 EXPERIENCE, PLEASANT OR 1322 00:48:51,073 --> 00:48:52,441 UNPLEASANT, THAT YOU'VE HAD 1323 00:48:52,441 --> 00:48:53,642 WITHIN THE LAST 24 HOURS. 1324 00:48:53,642 --> 00:48:55,110 AND THEY DESCRIBE IT VERY 1325 00:48:55,110 --> 00:48:55,678 BRIEFLY. 1326 00:48:55,678 --> 00:48:59,315 AND THIS IS JUST DATA FROM ROZ'S 1327 00:48:59,315 --> 00:49:01,951 ANALYSIS FROM HER GROUP, JUST 1328 00:49:01,951 --> 00:49:02,751 LOOKING AT THE DIFFERENCE 1329 00:49:02,751 --> 00:49:05,254 BETWEEN THOSE WHO ARE HIGH AND 1330 00:49:05,254 --> 00:49:09,458 LOW IN THE PHQ, LOOKING -- USING 1331 00:49:09,458 --> 00:49:10,759 COMPUTER VISION TO MEASURE 1332 00:49:10,759 --> 00:49:12,461 SMILING AND LOOKING AT THE 1333 00:49:12,461 --> 00:49:14,697 EVOLUTION OF SMILES AND CHEEK 1334 00:49:14,697 --> 00:49:16,465 RAISES, AND YOU CAN SEE SOME 1335 00:49:16,465 --> 00:49:19,468 VERY CLEAR DIFFERENTIATION FROM 1336 00:49:19,468 --> 00:49:21,770 THESE EARLY DATA. 1337 00:49:21,770 --> 00:49:26,642 AND NOW, I AM GOING TO TURN IT 1338 00:49:26,642 --> 00:49:31,413 OVER TO CHRISTIE WILSON MEN 1339 00:49:31,413 --> 00:49:32,815 DALHALL, CORE FACULTY MEMBER AT 1340 00:49:32,815 --> 00:49:35,150 OUR CENTER, AND ALSO IS ONE OF 1341 00:49:35,150 --> 00:49:40,856 THE CO-LEADERS OF THIS NETWORK. 1342 00:49:40,856 --> 00:49:44,226 >> OKAY, I THINK WE'RE ALMOST 1343 00:49:44,226 --> 00:49:45,794 OUT OF TIME, SO I'M JUST GOING 1344 00:49:45,794 --> 00:49:48,230 TO GIVE SOME REALLY GENERAL 1345 00:49:48,230 --> 00:49:49,331 THEMES HERE. 1346 00:49:49,331 --> 00:49:50,933 AND THIS TEXT IS ACTUALLY A LOT 1347 00:49:50,933 --> 00:49:52,234 SMALLER THAN IT WAS WHEN I LAST 1348 00:49:52,234 --> 00:49:54,370 SAW THESE SLIDE, BUT ONE OF THE 1349 00:49:54,370 --> 00:49:56,138 THEMES COMING OUT OF OUR NETWORK 1350 00:49:56,138 --> 00:49:59,742 IS REALLY THAT HOW WE DO 1351 00:49:59,742 --> 00:50:00,876 EMOTIONAL WELL-BEING RESEARCH 1352 00:50:00,876 --> 00:50:01,477 MATTERS. 1353 00:50:01,477 --> 00:50:02,911 GROUNDED IN THE WORK OF SOCIAL 1354 00:50:02,911 --> 00:50:06,348 JUSTICE SCHOLARS AND ACTIVISTS, 1355 00:50:06,348 --> 00:50:08,717 WE ARE REALLY CREATING SPACE TO 1356 00:50:08,717 --> 00:50:09,351 REIMAGINARY SEARCH THROUGH THE 1357 00:50:09,351 --> 00:50:11,287 LENS OF EQUITABLE AND COLLECTIVE 1358 00:50:11,287 --> 00:50:12,488 CARE AND TAKING STEPS TOWARDS 1359 00:50:12,488 --> 00:50:13,722 THAT VISION. 1360 00:50:13,722 --> 00:50:14,990 AND AGAIN I DON'T HAVE TIME TO 1361 00:50:14,990 --> 00:50:17,526 GET INTO DETAIL, BUT WE ARE 1362 00:50:17,526 --> 00:50:19,762 FUNDING COMMUNITY ENGAGED 1363 00:50:19,762 --> 00:50:22,398 RESEARCH, COMMUNITY ENGAGED 1364 00:50:22,398 --> 00:50:25,267 RESEARCH WAS A PART OF AND 1365 00:50:25,267 --> 00:50:26,535 INSPIRED US THINKING DIFFERENTLY 1366 00:50:26,535 --> 00:50:28,671 ABOUT A SUMMER WORKSHOP FOR 1367 00:50:28,671 --> 00:50:30,239 EMERGING SCHOLARS AND HOW WE 1368 00:50:30,239 --> 00:50:34,777 SUPPORT EARLY CAREER AND EMER 1369 00:50:34,777 --> 00:50:36,345 EMERGING SCHOLARS, PROVIDING A 1370 00:50:36,345 --> 00:50:39,415 FOUNDATION FOR LEARNING, 1371 00:50:39,415 --> 00:50:40,249 GROWING, AND COLLABORATING IN 1372 00:50:40,249 --> 00:50:40,983 COMMUNITY. 1373 00:50:40,983 --> 00:50:42,084 AND ONE OF THE UNANTICIPATED 1374 00:50:42,084 --> 00:50:44,553 OUTCOMES OF THAT SUMMER WORKSHOP 1375 00:50:44,553 --> 00:50:46,221 WAS THAT A GROUP WHO HAD BEEN 1376 00:50:46,221 --> 00:50:50,192 WITH US THAT WEEK HAS NOW 1377 00:50:50,192 --> 00:50:52,161 SELF-ORGANIZED INTO THE 1378 00:50:52,161 --> 00:50:54,330 SELF-NAMED COMMUNITY WE MERGE, 1379 00:50:54,330 --> 00:50:56,332 EMERGING WELL-BEING SCHOLARS 1380 00:50:56,332 --> 00:50:57,299 COLLECTIVE, AND THEY ARE 1381 00:50:57,299 --> 00:50:59,301 PURSUING WORK TO CENTER 1382 00:50:59,301 --> 00:51:00,636 WELL-BEING IN RESEARCH PRACTICES 1383 00:51:00,636 --> 00:51:01,503 AND CULTURE. 1384 00:51:01,503 --> 00:51:03,639 AND I DON'T THINK I HAVE TIME TO 1385 00:51:03,639 --> 00:51:04,940 REALLY SHARE MUCH ABOUT THEIR 1386 00:51:04,940 --> 00:51:06,041 WORK UNFORTUNATELY, BUT I DID 1387 00:51:06,041 --> 00:51:08,010 WANT TO SHOW THIS BEAUTIFUL 1388 00:51:08,010 --> 00:51:09,578 PICTURE OF THEM. 1389 00:51:09,578 --> 00:51:11,447 AND I THINK THIS PICTURE 1390 00:51:11,447 --> 00:51:14,950 REALLY -- THEY REFER TO THIS AS 1391 00:51:14,950 --> 00:51:17,152 THE CINNAMON ROLL HUG, AND I 1392 00:51:17,152 --> 00:51:19,488 THINK THIS PICTURE REALLY 1393 00:51:19,488 --> 00:51:22,458 CAPTURES, YOU KNOW, THE FEELING 1394 00:51:22,458 --> 00:51:25,160 OF TOGETHERNESS AND CARE THAT IS 1395 00:51:25,160 --> 00:51:26,161 REALLY RADIATING OUT IN THE WORK 1396 00:51:26,161 --> 00:51:27,463 THAT THEY ARE DOING TO SHAPE THE 1397 00:51:27,463 --> 00:51:29,698 FIELD. 1398 00:51:29,698 --> 00:51:34,203 SO WITH THAT, I WILL JUST -- IF 1399 00:51:34,203 --> 00:51:35,304 YOU'D LIKE TO LEARN MORE ABOUT 1400 00:51:35,304 --> 00:51:37,306 OUR NETWORK, YOU CAN SIGN UP AT 1401 00:51:37,306 --> 00:51:39,742 OUR WEBSITE FOR ANOUNMENTS AND 1402 00:51:39,742 --> 00:51:40,609 OPPORTUNITIES. 1403 00:51:40,609 --> 00:51:43,245 THIS QR CODE WILL TAKE YOU 1404 00:51:43,245 --> 00:51:45,781 DIRECTLY THERE TO THE SIGNUP, SO 1405 00:51:45,781 --> 00:51:46,949 THANK YOU SO MUCH FOR LISTENING. 1406 00:51:46,949 --> 00:51:57,126 [APPLAUSE] 1407 00:52:04,733 --> 00:52:06,068 >> OKAY. 1408 00:52:06,068 --> 00:52:07,836 HI, I AM CRYSTAL PARK, AND HOPE 1409 00:52:07,836 --> 00:52:09,571 YOU ALL ARE HAVING A GOOD 1410 00:52:09,571 --> 00:52:11,006 MORNING WHEREVER YOU ARE. 1411 00:52:11,006 --> 00:52:13,542 THIS IS JUST A WONDERFUL 1412 00:52:13,542 --> 00:52:15,077 OPPORTUNITY TO SHARE, AND WHAT 1413 00:52:15,077 --> 00:52:17,646 WE WERE ASKED TO DO IS TALK 1414 00:52:17,646 --> 00:52:19,615 ABOUT SORT OF WHAT WE HAVE BEEN 1415 00:52:19,615 --> 00:52:23,252 DOING AND WHERE WE'RE THINKING 1416 00:52:23,252 --> 00:52:25,988 ABOUT GOING NEXT, AND JUST KIND 1417 00:52:25,988 --> 00:52:27,990 OF GIVING A QUICK SUMMARY. 1418 00:52:27,990 --> 00:52:30,459 SO WE ARE REALLY GRATEFUL FOR 1419 00:52:30,459 --> 00:52:32,127 THE OPPORTUNITY TO BE PART OF 1420 00:52:32,127 --> 00:52:37,499 THIS AND FEEL LIKE THESE ARE 1421 00:52:37,499 --> 00:52:38,934 JUST WONDERFUL DIRECTIONS TO BE 1422 00:52:38,934 --> 00:52:39,802 MOVING IN. 1423 00:52:39,802 --> 00:52:41,103 THE GOALS OF OUR NETWORK, AND 1424 00:52:41,103 --> 00:52:44,606 THESE ARE OUR AIMS, IS TO CREATE 1425 00:52:44,606 --> 00:52:45,674 A TAXONOMY OF ESSENTIAL 1426 00:52:45,674 --> 00:52:47,476 COMPONENTS OF EMOTIONAL 1427 00:52:47,476 --> 00:52:50,012 WELL-BEING, TO ESTABLISH AN 1428 00:52:50,012 --> 00:52:50,979 EMOTIONAL WELL-BEING MEASURES 1429 00:52:50,979 --> 00:52:52,481 TOOLKIT, AND IDENTIFY GAPS, 1430 00:52:52,481 --> 00:52:54,183 CREATE NEW MEASURES, AND THEN 1431 00:52:54,183 --> 00:52:56,819 FINALLY, TO IDENTIFY POTENTIAL 1432 00:52:56,819 --> 00:52:59,421 MECHANISMS THROUGH MBIs, 1433 00:52:59,421 --> 00:53:01,557 MIND-BODY INTERVENTIONS, PROMOTE 1434 00:53:01,557 --> 00:53:03,192 EMOTIONAL WELL-BEING. 1435 00:53:03,192 --> 00:53:06,028 SO I KIND OF MAPPED ON OUR 1436 00:53:06,028 --> 00:53:09,064 ACCOMPLACCOMPLISHMENTS TO THOSE, 1437 00:53:09,064 --> 00:53:11,099 AND DR. KELLEY AND SOME OTHERS 1438 00:53:11,099 --> 00:53:12,167 HAVE ALREADY REFERRED TO SOME OF 1439 00:53:12,167 --> 00:53:13,802 WHAT WE HAVE BEEN DOING. 1440 00:53:13,802 --> 00:53:15,971 SO DURING THE DISCUSSIONS VERY 1441 00:53:15,971 --> 00:53:18,640 EARLY ON WITH THESE NETWORKS, A 1442 00:53:18,640 --> 00:53:20,409 NUMBER OF US HAD WANTED TO LOOK 1443 00:53:20,409 --> 00:53:23,278 AT TAXONOMIES AND TRY TO CREATE 1444 00:53:23,278 --> 00:53:24,880 SOME COMMON UNDERSTANDING, 1445 00:53:24,880 --> 00:53:27,549 COMMON LANGUAGE ACROSS THE 1446 00:53:27,549 --> 00:53:29,585 GROUPS, AND SO WE HAD A WORKING 1447 00:53:29,585 --> 00:53:32,488 GROUP THAT WORKED VERY HARD THAT 1448 00:53:32,488 --> 00:53:35,457 MET A LOT AND DID A LOT OF 1449 00:53:35,457 --> 00:53:38,327 HOMEWORK, AND WE ENDED UP WITH 1450 00:53:38,327 --> 00:53:40,262 ALL SIX NETWORKS KIND OF BEING 1451 00:53:40,262 --> 00:53:41,897 PART OF THAT PAPER. 1452 00:53:41,897 --> 00:53:44,399 SO I TOOK -- I'M FIRST AUTHOR ON 1453 00:53:44,399 --> 00:53:45,701 THAT PAPER BUT IT WAS DEFINITELY 1454 00:53:45,701 --> 00:53:49,638 A VILLAGE THAT PRODUCED THAT 1455 00:53:49,638 --> 00:53:50,973 DISCUSSION AND THE RESULTING 1456 00:53:50,973 --> 00:53:55,744 PAPER THAT CAME FROM IT. 1457 00:53:55,744 --> 00:53:57,379 SH IT'S BEEN CITED ALREADY 1458 00:53:57,379 --> 00:53:59,081 43 TIMES BUT I THINK THAT'S A 1459 00:53:59,081 --> 00:54:00,782 NUMBER THAT'S REALLY GOING TO 1460 00:54:00,782 --> 00:54:02,117 GROW OVER TIME, A LOT OF PEOPLE 1461 00:54:02,117 --> 00:54:02,985 ARE INTERESTED IN IT. 1462 00:54:02,985 --> 00:54:04,453 AND THEN IT DID CREATE THIS 1463 00:54:04,453 --> 00:54:09,391 REALLY NICE SET OF -- I'M 1464 00:54:09,391 --> 00:54:11,560 STEALING MY OWN THUNDER HERE. 1465 00:54:11,560 --> 00:54:12,127 OH, WOW. 1466 00:54:12,127 --> 00:54:14,396 THIS IS SO NON-INTUITIVE. 1467 00:54:14,396 --> 00:54:24,673 IT LIKE -- YEAH. 1468 00:54:33,482 --> 00:54:36,251 THEN THERE WAS THIS 1469 00:54:36,251 --> 00:54:37,119 COMMENTARIES, GETTING PEOPLE TO 1470 00:54:37,119 --> 00:54:39,588 THINK MORE DEEPLY ABOUT WHAT 1471 00:54:39,588 --> 00:54:40,322 EMOTIONAL WELL-BEING IS, WHICH 1472 00:54:40,322 --> 00:54:41,857 IS KIND OF HOW WE KICKED OFF THE 1473 00:54:41,857 --> 00:54:44,092 MORNING, AND THEN AFTER THAT, WE 1474 00:54:44,092 --> 00:54:45,961 HAD A KIND OF CLOSING COMMENTARY 1475 00:54:45,961 --> 00:54:49,464 IN THAT SAME SPECIAL ISSUE. 1476 00:54:49,464 --> 00:54:52,901 SO REALLY A LOT OF THOUGHT IN 1477 00:54:52,901 --> 00:54:56,305 THAT SPECIAL ISSUE. 1478 00:54:56,305 --> 00:54:57,839 IN TERMS OF MEASUREMENT, WE 1479 00:54:57,839 --> 00:54:59,474 CREATED A SUBJECTIVE MEASURES 1480 00:54:59,474 --> 00:54:59,841 REPOSITORY. 1481 00:54:59,841 --> 00:55:02,144 THESE ARE SELF-REPORT AND OTHER 1482 00:55:02,144 --> 00:55:03,378 REPORT MEASURES. 1483 00:55:03,378 --> 00:55:05,080 THERE ARE OVER 100 OF THESE 1484 00:55:05,080 --> 00:55:06,415 AVAILABLE FOR PUBLIC ACCESS, AND 1485 00:55:06,415 --> 00:55:10,686 THAT'S THE VERY LONG EMAIL 1486 00:55:10,686 --> 00:55:12,254 ADDRESS WEBSITE FOR IT. 1487 00:55:12,254 --> 00:55:14,256 THIS IS A COLLABORATION WITH THE 1488 00:55:14,256 --> 00:55:16,258 SCIENCE AND BEHAVIOR CHANGE, 1489 00:55:16,258 --> 00:55:17,259 THEY HAVE ALREADY BEEN DOING A 1490 00:55:17,259 --> 00:55:18,660 LOT OF STRESS AND RESILIENCE 1491 00:55:18,660 --> 00:55:20,095 MEASURES SO WE KIND OF 1492 00:55:20,095 --> 00:55:22,831 INTEGRATED AND WORKED WITH THEM. 1493 00:55:22,831 --> 00:55:24,232 THIS IS BEING WIDELY USED, I 1494 00:55:24,232 --> 00:55:25,534 DON'T HAVE THE NUMBERS RIGHT 1495 00:55:25,534 --> 00:55:27,035 NOW, BUT IT'S REALLY DESIGNED TO 1496 00:55:27,035 --> 00:55:30,472 BE A RESOURCE TO HELP PROMOTE 1497 00:55:30,472 --> 00:55:34,309 FUTURE RESEARCH IN THIS AREA. 1498 00:55:34,309 --> 00:55:35,978 THE SECOND THING THAT WE DID WAS 1499 00:55:35,978 --> 00:55:38,013 WE HAD A FIRST CALL FOR SEED 1500 00:55:38,013 --> 00:55:40,315 GRANTS, THIS IS OUR FIRST ROUND 1501 00:55:40,315 --> 00:55:41,583 OF SEED GRANTS REALLY TRYING TO 1502 00:55:41,583 --> 00:55:42,651 SEEK OUT PEOPLE WHO WERE 1503 00:55:42,651 --> 00:55:43,552 DEVELOPING MEASURES TO FILL IN 1504 00:55:43,552 --> 00:55:45,387 SOME OF THOSE GAPS. 1505 00:55:45,387 --> 00:55:48,056 SO A LOT OF THE ISSUES WERE WITH 1506 00:55:48,056 --> 00:55:50,792 DIFFERENT POPULATIONS, SPECIAL 1507 00:55:50,792 --> 00:55:52,861 POPULATIONS, AGE GROUPS, 1508 00:55:52,861 --> 00:55:53,695 INTELLECTUAL DISABILITIES, 1509 00:55:53,695 --> 00:55:54,363 THINGS LIKE THAT. 1510 00:55:54,363 --> 00:55:58,834 SO WE HAD A REALLY ROBUST SET OF 1511 00:55:58,834 --> 00:56:01,103 PEOPLE APPLYING, REALLY 1512 00:56:01,103 --> 00:56:03,505 INTERESTING IDEAS, AND MOST OF 1513 00:56:03,505 --> 00:56:04,706 THOSE ARE ONGOING. 1514 00:56:04,706 --> 00:56:06,475 I THINK ONE OR TWO MIGHT HAVE 1515 00:56:06,475 --> 00:56:07,943 FINISHED. 1516 00:56:07,943 --> 00:56:09,745 BUT THAT'S VERY EXCITING TO KIND 1517 00:56:09,745 --> 00:56:11,913 OF BE PUSHING THOSE MEASURES 1518 00:56:11,913 --> 00:56:13,248 FORWARD. 1519 00:56:13,248 --> 00:56:15,550 AND THEN DR. KELLEY AND A 1520 00:56:15,550 --> 00:56:16,818 COUPLE -- ALREADY SOME OF THE 1521 00:56:16,818 --> 00:56:17,819 SYSTEMATIC REVIEWS THAT WE'VE 1522 00:56:17,819 --> 00:56:19,221 DONE HAVE BEEN REFERRED TO. 1523 00:56:19,221 --> 00:56:21,156 WE'VE BEEN VERY ACTIVE WITH THE 1524 00:56:21,156 --> 00:56:23,025 SYSTEMATIC REVIEWS, AND AS I'LL 1525 00:56:23,025 --> 00:56:23,859 MENTION, WE HAVE SOME OTHERS 1526 00:56:23,859 --> 00:56:25,894 GOING ON, BUT THESE ONES ON 1527 00:56:25,894 --> 00:56:28,764 MEASURES, AGAIN, VERY USEFUL 1528 00:56:28,764 --> 00:56:31,299 CONTRIBUTION TO THE FIELD FOR 1529 00:56:31,299 --> 00:56:33,502 PEOPLE TO BE ABLE TO FIND THEM. 1530 00:56:33,502 --> 00:56:35,137 AND THEN WE'RE NOW KIND OF 1531 00:56:35,137 --> 00:56:37,406 SHIFTING OUR FOCUS INTO THAT 1532 00:56:37,406 --> 00:56:39,074 THIRD AIM, WHICH IS REALLY 1533 00:56:39,074 --> 00:56:43,378 IDENTIFYING MECHANISMS AND 1534 00:56:43,378 --> 00:56:45,380 EMMELINE JUST MENTIONED, IS 1535 00:56:45,380 --> 00:56:46,581 EMOTIONAL WELL-BEING AN OUTCOME, 1536 00:56:46,581 --> 00:56:48,784 IS IT A MECHANISM OF OTHER 1537 00:56:48,784 --> 00:56:49,518 OUTCOMES, AND THAT'S SOMETHING 1538 00:56:49,518 --> 00:56:51,920 THAT WE'VE BEEN VERY, VERY 1539 00:56:51,920 --> 00:56:53,922 INTERESTED IN IN YOGA, 1540 00:56:53,922 --> 00:56:55,190 MEDITATION, OTHER MIND-BODY 1541 00:56:55,190 --> 00:56:57,392 MODALITIES IS REALLY LOOKING AT 1542 00:56:57,392 --> 00:57:00,429 HOW DO THOSE AFFECT EMOTIONAL 1543 00:57:00,429 --> 00:57:02,798 WELL-BEING AND THROUGH EMOTIONAL 1544 00:57:02,798 --> 00:57:03,532 WELL-BEING, OTHER OUTCOMES. 1545 00:57:03,532 --> 00:57:05,967 SO WE HAVE A CURRENT CYST TI 1546 00:57:05,967 --> 00:57:10,672 MATIC REVIEW OF THE MECHANIS 1547 00:57:10,672 --> 00:57:11,573 MECHANISTIC -- WE STARTED WITH 1548 00:57:11,573 --> 00:57:12,607 11,000 ARTICLES AND ARE MAKING 1549 00:57:12,607 --> 00:57:14,242 OUR WAY THROUGH THOSE TO SEE 1550 00:57:14,242 --> 00:57:16,178 WHICH ONES NEED FULL TEXT AND 1551 00:57:16,178 --> 00:57:20,182 WE'RE ALMOST AT THE END OF THAT 1552 00:57:20,182 --> 00:57:21,717 PROCESS AS A REALLY BIG LIFT, 1553 00:57:21,717 --> 00:57:24,319 BUT WE'RE DOING THAT. 1554 00:57:24,319 --> 00:57:29,825 WE'RE ALSO -- SANDY, OUR THIRD 1555 00:57:29,825 --> 00:57:34,396 P.I., CAM KAMIKO IS HERE, THEY'E 1556 00:57:34,396 --> 00:57:36,765 WORKING ON OTHER SYSTEMATIC 1557 00:57:36,765 --> 00:57:37,299 REVIEWS. 1558 00:57:37,299 --> 00:57:39,534 SANDY IS INTERESTED IN SOME OF 1559 00:57:39,534 --> 00:57:41,203 THE INTELLECTUAL DISABILITIES 1560 00:57:41,203 --> 00:57:43,405 AND HOW YOU MEASURE EMOTIONAL 1561 00:57:43,405 --> 00:57:45,941 WELL-BEING IN SOME DIFFERENT 1562 00:57:45,941 --> 00:57:46,475 POPULATIONS. 1563 00:57:46,475 --> 00:57:48,143 AND WE'RE ALSO WORKING ON A 1564 00:57:48,143 --> 00:57:50,912 CONCEPTUAL ARTICLE ON EMOTIONAL 1565 00:57:50,912 --> 00:57:52,080 WELL-BEING MEDIATION AND REALLY 1566 00:57:52,080 --> 00:57:54,850 TRYING TO LOOK AT THAT SORT OF 1567 00:57:54,850 --> 00:57:56,651 MECHANISTICALLY. 1568 00:57:56,651 --> 00:57:58,153 OUR NETWORKING ACTIVITIES, WE'VE 1569 00:57:58,153 --> 00:57:59,454 BEEN VERY DELIBERATE IN REALLY 1570 00:57:59,454 --> 00:58:03,358 TRYING TO GET PEOPLE TO THINK 1571 00:58:03,358 --> 00:58:04,159 ABOUT EMOTIONAL WELL-BEING, SO 1572 00:58:04,159 --> 00:58:07,629 WE'VE BEEN REALLY TRYING TO BE 1573 00:58:07,629 --> 00:58:08,530 PRESENCE AT THE CONFERENCES WE 1574 00:58:08,530 --> 00:58:08,864 ATTEND. 1575 00:58:08,864 --> 00:58:09,865 THE FIRST YEAR AT THE 1576 00:58:09,865 --> 00:58:11,199 ASSOCIATION FOR PSYCH SCIENCE IN 1577 00:58:11,199 --> 00:58:13,001 CHICAGO, WE HAD A BOOTH AND 1578 00:58:13,001 --> 00:58:14,302 HANDING OUT THINGS AND DOING 1579 00:58:14,302 --> 00:58:16,171 SOME POLLS AND REALLY TRYING TO 1580 00:58:16,171 --> 00:58:17,239 GET PEOPLE TO THINK ABOUT IT. 1581 00:58:17,239 --> 00:58:21,810 WE ALSO HAD A REALLY GREAT 1582 00:58:21,810 --> 00:58:23,078 SYMPOSIUM THERE. 1583 00:58:23,078 --> 00:58:26,915 2023, WE HAD A SUMMIT THE DAY 1584 00:58:26,915 --> 00:58:28,316 BEFORE, WE DID THE SAME THING 1585 00:58:28,316 --> 00:58:30,185 AND PARTNERED WITH EMOTICON THIS 1586 00:58:30,185 --> 00:58:31,153 YEAR AT SBM. 1587 00:58:31,153 --> 00:58:32,721 SO THOSE WERE VERY SUCCESSFUL, I 1588 00:58:32,721 --> 00:58:33,688 THINK, BRINGING TOGETHER SOME OF 1589 00:58:33,688 --> 00:58:34,923 OUR GRANTEES, GETTING OTHER 1590 00:58:34,923 --> 00:58:35,824 PEOPLE AT THE CONFERENCE TO SAY 1591 00:58:35,824 --> 00:58:37,793 WHAT DO YOU MEAN, EMOTIONAL 1592 00:58:37,793 --> 00:58:39,161 WELL-BEING. 1593 00:58:39,161 --> 00:58:40,128 BECAUSE EVERYBODY HEARS IT AND 1594 00:58:40,128 --> 00:58:41,129 THEY'RE STILL THINKING YOU MEAN 1595 00:58:41,129 --> 00:58:42,430 LIE LOWERING DEPRESSION? 1596 00:58:42,430 --> 00:58:43,665 IT'S LIKE, NOT EXACTLY. 1597 00:58:43,665 --> 00:58:46,401 LIKE, WE'RE REALLY TRYING TO 1598 00:58:46,401 --> 00:58:47,369 PUSH THAT PARADIGM. 1599 00:58:47,369 --> 00:58:50,405 WE HAD SOME DATA BLITZ 1600 00:58:50,405 --> 00:58:52,641 SUPPLEMENTS, AND THEN WE HAVE A 1601 00:58:52,641 --> 00:58:54,442 PROGRAM THAT I JUST COMPLETED A 1602 00:58:54,442 --> 00:58:55,577 YEAR OF WORKING WITH SOME 1603 00:58:55,577 --> 00:58:55,811 FELLOWS. 1604 00:58:55,811 --> 00:58:58,380 WE HAVE A SCHOLARS AND FELLOWS 1605 00:58:58,380 --> 00:59:02,684 PROGRAM, SCHOLARS JUST MEET SOME 1606 00:59:02,684 --> 00:59:06,021 SMALLER MILESTONES AND THEN OUR 1607 00:59:06,021 --> 00:59:07,222 NAMED SCHOLARS, WE WORK WITH 1608 00:59:07,222 --> 00:59:07,556 THEM. 1609 00:59:07,556 --> 00:59:09,724 BUT WITH THE FELLOWS, I WORKED 1610 00:59:09,724 --> 00:59:10,091 MORE CLOSELY. 1611 00:59:10,091 --> 00:59:11,993 WE HAD A SYLLABUS ON HOW TO 1612 00:59:11,993 --> 00:59:14,963 DESIGN AND THINK ABOUT MIND-BODY 1613 00:59:14,963 --> 00:59:16,631 INTERVENTIONS AND EMOTIONAL 1614 00:59:16,631 --> 00:59:18,400 WELL-BEING IN A MECHANISTIC WAY, 1615 00:59:18,400 --> 00:59:19,901 AND THAT WAS JUST REALLY, REALLY 1616 00:59:19,901 --> 00:59:22,404 FUN, AND ALL OF THEM ARE 1617 00:59:22,404 --> 00:59:24,673 GRADUATE STUDENTS OR POSTDOCS OR 1618 00:59:24,673 --> 00:59:27,075 ON K AWARDS SO THEY'RE ALL LIKE 1619 00:59:27,075 --> 00:59:27,943 INTEGRATING THIS INTO THE THINGS 1620 00:59:27,943 --> 00:59:29,077 THAT THEY'RE DOING. 1621 00:59:29,077 --> 00:59:36,318 AND IT LOOKS LIKE SANDY AND FU 1622 00:59:36,318 --> 00:59:37,652 FUMIKO MAY HAVE ANOTHER FELLOW 1623 00:59:37,652 --> 00:59:40,388 PROGRAM THIS YEAR FOCUSING ON 1624 00:59:40,388 --> 00:59:41,256 META-ANALYSIS, SO THAT'S ALSO 1625 00:59:41,256 --> 00:59:42,958 REALLY EXCITING. 1626 00:59:42,958 --> 00:59:45,727 AND THEN FOR OUTREACH AND 1627 00:59:45,727 --> 00:59:47,495 DISSEMINATION, AS I MENTIONED, 1628 00:59:47,495 --> 00:59:48,597 WE'VE DONE A LOT OF 1629 00:59:48,597 --> 00:59:49,965 PRESENTATIONS AND SYMPOSIA. 1630 00:59:49,965 --> 00:59:52,934 WE'VE HAD AN ONGOING LECTURE 1631 00:59:52,934 --> 00:59:57,405 SERIES WITH THE INSTITUTE FOR 1632 00:59:57,405 --> 01:00:00,242 COLLABORATION ON HEALTH AT 1633 01:00:00,242 --> 01:00:03,011 U-CONN, AND WE HAVE COLLABORATED 1634 01:00:03,011 --> 01:00:04,446 WITH THEM IN BRINGING IN 1635 01:00:04,446 --> 01:00:06,014 SPEAKERS OR DOING ONLINE STUFF, 1636 01:00:06,014 --> 01:00:07,816 AND THOSE ARE ALL ARCHIVED SO 1637 01:00:07,816 --> 01:00:08,483 THEY'RE AVAILABLE FOR ANYBODY 1638 01:00:08,483 --> 01:00:09,784 WHO WANTS TO SEE THEM, WHICH IS 1639 01:00:09,784 --> 01:00:11,286 JUST REALLY NICE FOR PEOPLE TO 1640 01:00:11,286 --> 01:00:12,654 BE ABLE TO FIND THEM. 1641 01:00:12,654 --> 01:00:17,292 AND WE DID DO THIS -- U-CONN HAS 1642 01:00:17,292 --> 01:00:19,261 THESE ONE-CREDIT POP-UP COURSES 1643 01:00:19,261 --> 01:00:21,630 SO WE DID AN EMOTIONAL 1644 01:00:21,630 --> 01:00:23,732 WELL-BEING ONE THAT SANDY REALLY 1645 01:00:23,732 --> 01:00:24,132 SPEARHEADED. 1646 01:00:24,132 --> 01:00:25,667 I DID PART OF THE MODULE ON 1647 01:00:25,667 --> 01:00:28,169 MEANING AND PURPOSE AND FUMIKO 1648 01:00:28,169 --> 01:00:29,671 DID PART OF A MODULE TOO. 1649 01:00:29,671 --> 01:00:31,840 SO THIS COURSE WAS TAKEN BY OVER 1650 01:00:31,840 --> 01:00:33,875 1800 U-CONN STUDENTS SO FAR, AND 1651 01:00:33,875 --> 01:00:35,443 IT'S ALL PRERECORDED AND KIND OF 1652 01:00:35,443 --> 01:00:37,078 LOCKED AND LOADED, SO THEY CAN 1653 01:00:37,078 --> 01:00:41,082 OFFER IT AGAIN, AND THE IDEA IS 1654 01:00:41,082 --> 01:00:42,484 EVENTUALLY TO ALLOW THE GENERAL 1655 01:00:42,484 --> 01:00:49,391 PUBLIC TO TAKE THIS COURSE SO WE 1656 01:00:49,391 --> 01:00:51,159 COVERED ALL OF THE ELEMENTS OF 1657 01:00:51,159 --> 01:00:52,394 EMOTIONAL B THERE JUST A WAY TO 1658 01:00:52,394 --> 01:00:53,995 GET THAT MESSAGE OUT TO THE 1659 01:00:53,995 --> 01:00:54,429 GENERAL PUBLIC. 1660 01:00:54,429 --> 01:00:57,933 IN TERMS OF NEXT STEPS, 1661 01:00:57,933 --> 01:00:59,100 OBVIOUSLY WE'RE CONTINUING WITH 1662 01:00:59,100 --> 01:01:00,435 THESE SYSTEMATIC REVIEWS, 1663 01:01:00,435 --> 01:01:02,070 THERE'S NO SMALL FEAT TO DO A 1664 01:01:02,070 --> 01:01:06,174 GOOD SYSTEMATIC REVIEW,. 1665 01:01:06,174 --> 01:01:09,244 I MENTIONED THE CONCEPTUAL 1666 01:01:09,244 --> 01:01:11,179 ARTICLE ON MIND-BODY 1667 01:01:11,179 --> 01:01:13,915 INTERVENTIONS, THE SEED GRANTS 1668 01:01:13,915 --> 01:01:15,150 AND THE LECTURE SERIES. 1669 01:01:15,150 --> 01:01:16,184 THE LAST THING I WANT TO LEAVE 1670 01:01:16,184 --> 01:01:17,552 AND WE WERE ASKED TO THINK ABOUT 1671 01:01:17,552 --> 01:01:18,553 WAYS TO COLLABORATE WITH THESE 1672 01:01:18,553 --> 01:01:23,725 OTHER NETWORKS, ALL OF YOU AND 1673 01:01:23,725 --> 01:01:25,226 BEYOND, SO TO REALLY THINK ABOUT 1674 01:01:25,226 --> 01:01:26,428 THE QUESTIONS THAT REMAIN. 1675 01:01:26,428 --> 01:01:28,964 WE FEEL LIKE THIS GROUP 1676 01:01:28,964 --> 01:01:31,333 COLLECTIVELY IS DOING A LOT OF 1677 01:01:31,333 --> 01:01:33,034 FOUNDATIONAL WORK, WE'RE REALLY 1678 01:01:33,034 --> 01:01:34,736 THINKING ABOUT MEASURES, WE'RE 1679 01:01:34,736 --> 01:01:37,372 REALLY THINKING ABOUT HOW TO 1680 01:01:37,372 --> 01:01:38,273 CARVE OUT THIS AS SEPARATE FROM 1681 01:01:38,273 --> 01:01:39,474 OTHER THINGS THAT PEOPLE HAVE 1682 01:01:39,474 --> 01:01:42,177 BEEN STUDYING AND DOING, AND 1683 01:01:42,177 --> 01:01:43,778 OBVIOUSLY THERE'S A LOT OF SPACE 1684 01:01:43,778 --> 01:01:47,949 FOR INTERVENTIONS, BUT WE REALLY 1685 01:01:47,949 --> 01:01:49,250 WANT TO UNDERSTAND WHAT THOSE -- 1686 01:01:49,250 --> 01:01:50,418 AND REALLY DEFINE AND LAY OUT 1687 01:01:50,418 --> 01:01:51,553 FOR THE FIELD NOW THAT WE'VE 1688 01:01:51,553 --> 01:01:54,990 DONE ALL THIS FOUNDATIONAL WORK, 1689 01:01:54,990 --> 01:01:56,091 WHAT QUESTIONS DO WE NEED TO 1690 01:01:56,091 --> 01:01:56,558 ASK. 1691 01:01:56,558 --> 01:02:01,463 I THINK THAT THIS IS A VERY 1692 01:02:01,463 --> 01:02:02,197 EXCITING NEXT STEP THAT WILL BE 1693 01:02:02,197 --> 01:02:03,932 A GREAT WAY TO SORT OF WRAP UP 1694 01:02:03,932 --> 01:02:08,169 THIS PHASE OF THE EMOTIONAL 1695 01:02:08,169 --> 01:02:09,738 WELL-BEING NETWORKS. 1696 01:02:09,738 --> 01:02:10,071 SO THAT'S IT. 1697 01:02:10,071 --> 01:02:10,505 THANK YOU. 1698 01:02:10,505 --> 01:02:19,748 [APPLAUSE] 1699 01:02:19,748 --> 01:02:20,448 >> GOOD MORNING. 1700 01:02:20,448 --> 01:02:22,684 IT IS MY PLEASURE TO TALK ABOUT 1701 01:02:22,684 --> 01:02:24,019 THE EMOTIONAL WELL-BEING AND 1702 01:02:24,019 --> 01:02:26,087 ECONOMIC BURDEN OF DISEASE 1703 01:02:26,087 --> 01:02:27,188 RESEARCH NETWORK ON BEHALF OF 1704 01:02:27,188 --> 01:02:29,157 MYSELF AND DR. MICHELLE MARTIN. 1705 01:02:29,157 --> 01:02:33,061 OUR TEAM IS TRULY 1706 01:02:33,061 --> 01:02:33,995 MULTIDISCIPLINARY. 1707 01:02:33,995 --> 01:02:35,430 I'M AN ECONOMIST BY TRAINING, 1708 01:02:35,430 --> 01:02:36,731 DR. MARTIN IS A PSYCHOLOGIST. 1709 01:02:36,731 --> 01:02:39,334 WE HAVE DR. LEONG AND 1710 01:02:39,334 --> 01:02:40,735 DR. SCHWARTZ WHO ARE CLINICIANS 1711 01:02:40,735 --> 01:02:41,970 TO BRING THE CLINICAL 1712 01:02:41,970 --> 01:02:46,408 PERSPECTIVE TO OUR TEAM, AND WE 1713 01:02:46,408 --> 01:02:49,744 HAVE TWO PART-TIME COORDINATORS 1714 01:02:49,744 --> 01:02:56,117 FROM OUR -- YES. 1715 01:02:56,117 --> 01:02:58,319 THE MISSION OF OUR NETWORK WAS 1716 01:02:58,319 --> 01:02:59,654 TO DEVELOP KNOWLEDGE ABOUT THE 1717 01:02:59,654 --> 01:03:00,989 IMPACT THAT ECONOMIC BURDEN OF 1718 01:03:00,989 --> 01:03:03,825 DISEASE MAY HAVE ON EMOTIONAL 1719 01:03:03,825 --> 01:03:04,626 WELL-BEING FOR PATIENTS AND 1720 01:03:04,626 --> 01:03:06,594 FAMILIES WITH THE IDEA THEN TO 1721 01:03:06,594 --> 01:03:07,729 DEVELOP THE STRATEGIES THAT WE 1722 01:03:07,729 --> 01:03:10,065 NEED TO REDUCE THAT IMPACT. 1723 01:03:10,065 --> 01:03:11,132 BY ECONOMIC BURDEN OF DISEASE, 1724 01:03:11,132 --> 01:03:12,934 WHAT WE MEAN IS THE BURDEN THAT 1725 01:03:12,934 --> 01:03:16,137 COMES WITH HIGH COST OF CARE, 1726 01:03:16,137 --> 01:03:17,705 THE COST OF MANAGING ILLNESS, 1727 01:03:17,705 --> 01:03:20,708 THE TIME OF WORK THAT IS NEEDED, 1728 01:03:20,708 --> 01:03:22,210 WHICH MAY RESULT IN LOSS OF 1729 01:03:22,210 --> 01:03:23,945 INCOME AND ALL THOSE OTHER 1730 01:03:23,945 --> 01:03:25,080 ECONOMIC CONSEQUENCES OF A 1731 01:03:25,080 --> 01:03:28,450 DISEASE. 1732 01:03:28,450 --> 01:03:30,485 AND THEN WITH OUR NETWORK, WE 1733 01:03:30,485 --> 01:03:31,786 STILL KNOW VERY LITTLE ABOUT 1734 01:03:31,786 --> 01:03:34,089 THIS IMPACT SO WE WANT TO STUDY 1735 01:03:34,089 --> 01:03:36,324 THAT BUT ALSO MEDIATORS AND 1736 01:03:36,324 --> 01:03:39,327 MODERATORS OF THAT RELATIONSHIP 1737 01:03:39,327 --> 01:03:41,729 BETWEEN BURDEN ON EMOTIONAL 1738 01:03:41,729 --> 01:03:42,230 WELL-BEING. 1739 01:03:42,230 --> 01:03:43,064 WE HAD THREE AIMS. 1740 01:03:43,064 --> 01:03:45,633 ONE WAS TO BUILD A 1741 01:03:45,633 --> 01:03:46,801 MULTIDISCIPLINARY COLLABORATIVE 1742 01:03:46,801 --> 01:03:48,803 NETWORK TO ADVANCE THE RESEARCH. 1743 01:03:48,803 --> 01:03:50,738 THE SECOND WAS TO IMPLEMENT A 1744 01:03:50,738 --> 01:03:52,240 PILOT PROJECT PROGRAM, AND THEN 1745 01:03:52,240 --> 01:03:56,311 ALSO THE THIRD ONE WAS TO SHARE 1746 01:03:56,311 --> 01:03:57,979 OPPORTUNITIES, PRODUCTS AND 1747 01:03:57,979 --> 01:03:58,546 RESOURCES AT LARGE WITH THE 1748 01:03:58,546 --> 01:03:59,781 FIELD TO ACCELERATE THIS 1749 01:03:59,781 --> 01:04:05,120 RESEARCH. 1750 01:04:05,120 --> 01:04:07,422 SO WITH THE FIRST AIM WE REALLY 1751 01:04:07,422 --> 01:04:08,756 WANTED TO BRING TOGETHER THE 1752 01:04:08,756 --> 01:04:09,858 PEOPLE -- THE RESEARCHERS WHO 1753 01:04:09,858 --> 01:04:12,927 WERE STUDYING THE ECONOMIC 1754 01:04:12,927 --> 01:04:14,162 BURDEN OF DISEASE AND RAISE 1755 01:04:14,162 --> 01:04:15,763 THEIR AWARENESS ABOUT EMOTIONAL 1756 01:04:15,763 --> 01:04:17,098 WELL-BEING AND INTEREST IN 1757 01:04:17,098 --> 01:04:19,834 STUDYING THAT. 1758 01:04:19,834 --> 01:04:22,937 AND ALSO RAISE INTEREST AMONG 1759 01:04:22,937 --> 01:04:24,372 THOSE WHO WERE STUDYING 1760 01:04:24,372 --> 01:04:25,673 EMOTIONAL WELL-BEING TO CONSIDER 1761 01:04:25,673 --> 01:04:26,841 THE ECONOMIC BURDEN OF DISEASE 1762 01:04:26,841 --> 01:04:30,145 AS ONE OF THE FACTORS. 1763 01:04:30,145 --> 01:04:32,547 SO WE DO HAVE 162 PEOPLE WHO 1764 01:04:32,547 --> 01:04:33,882 HAVE EXPRESSED INTEREST IN THIS 1765 01:04:33,882 --> 01:04:36,985 WORK AND HAVE SIGNED UP AS 1766 01:04:36,985 --> 01:04:38,586 MEMBERS. 1767 01:04:38,586 --> 01:04:41,723 AND THE MAJORITY OF RESEARCH 1768 01:04:41,723 --> 01:04:43,758 RESEARCHERS -- THIS SLIDE IS 1769 01:04:43,758 --> 01:04:45,093 SMALL BUT -- TO SEE THE GRAPH, 1770 01:04:45,093 --> 01:04:46,027 MOST ARE RESEARCHERS AND 1771 01:04:46,027 --> 01:04:47,662 STUDENTS BUT WE ALSO HAVE 1772 01:04:47,662 --> 01:04:48,863 MEMBERS WHO ARE PATIENT 1773 01:04:48,863 --> 01:04:50,965 ADVOCATES, PATIENTS, CAREGIVERS, 1774 01:04:50,965 --> 01:04:51,733 AND THAT WAS VERY IMPORTANT TO 1775 01:04:51,733 --> 01:04:53,668 US TO BRING THAT PERSPECTIVE 1776 01:04:53,668 --> 01:04:56,638 INTO OUR WORK SO WE DO HAVE THE 1777 01:04:56,638 --> 01:05:00,041 VOICE OF WHO'S EXPERIENCING THIS 1778 01:05:00,041 --> 01:05:01,976 PROBLEM OF ECONOMIC BURDEN OF 1779 01:05:01,976 --> 01:05:03,178 DISEASE TO BRING THEIR VOICE 1780 01:05:03,178 --> 01:05:04,879 INTO THIS RESEARCH. 1781 01:05:04,879 --> 01:05:07,549 WE ALSO HAVE A GOOD PRESENTATION 1782 01:05:07,549 --> 01:05:09,517 OF RESEARCHERS ACROSS THE CAREER 1783 01:05:09,517 --> 01:05:10,285 TRAJECTORY, SO RAISING THE 1784 01:05:10,285 --> 01:05:11,586 PIPELINE OF RESEARCHERS IN THIS 1785 01:05:11,586 --> 01:05:13,188 FIELD. 1786 01:05:13,188 --> 01:05:15,590 WE HAVE HELD SEVERAL MEETINGS IN 1787 01:05:15,590 --> 01:05:17,091 PERSON IN WHICH A GROUP OF ABOUT 1788 01:05:17,091 --> 01:05:20,161 30 TO 35 PEOPLE ACTIVELY JOINED 1789 01:05:20,161 --> 01:05:23,131 IN OUR DISCUSSIONS. 1790 01:05:23,131 --> 01:05:24,566 AND IN THESE MEETINGS WE WORKED 1791 01:05:24,566 --> 01:05:25,767 ON EXPANDING AN INITIAL 1792 01:05:25,767 --> 01:05:27,068 FRAMEWORK THAT WE HAVE PROPOSED 1793 01:05:27,068 --> 01:05:29,871 TO STUDY THE IMPACT OF THE 1794 01:05:29,871 --> 01:05:32,273 ECONOMIC BURDEN OF DISEASE ON 1795 01:05:32,273 --> 01:05:32,740 EMOTIONAL WELL-BEING. 1796 01:05:32,740 --> 01:05:35,143 WE HAVE REVISED THAT AND 1797 01:05:35,143 --> 01:05:37,045 PUBLISHED THIS FRAMEWORK ON A 1798 01:05:37,045 --> 01:05:39,013 PUBLICATION WHERE WE ALSO 1799 01:05:39,013 --> 01:05:40,848 IDENTIFY SEVERAL AREAS OF 1800 01:05:40,848 --> 01:05:43,017 INQUIRIES FOR GUIDING THIS 1801 01:05:43,017 --> 01:05:45,019 RESEARCH. 1802 01:05:45,019 --> 01:05:46,554 FOR THE SECOND AIM WE'VE FUNDED 1803 01:05:46,554 --> 01:05:52,660 DIFFERENT TYPES OF PROJECTS, AND 1804 01:05:52,660 --> 01:05:53,795 WE SUMMARIZE HERE UNDER THREE 1805 01:05:53,795 --> 01:05:55,029 MAIN AREAS OF MEASUREMENT 1806 01:05:55,029 --> 01:06:00,368 MECHANISMS AND INTERVENTION. 1807 01:06:00,368 --> 01:06:02,470 SO UNDER MEASUREMENT, WE ARE 1808 01:06:02,470 --> 01:06:03,938 DEVELOPING MEASURES OF THE 1809 01:06:03,938 --> 01:06:04,639 PSYCHOLOGICAL FINANCIAL BURDEN 1810 01:06:04,639 --> 01:06:05,340 AND THEN OTHER PROJECTS THAT 1811 01:06:05,340 --> 01:06:07,942 HAVE LOOKED AT THE EXTENT OF THE 1812 01:06:07,942 --> 01:06:09,744 PROBLEM REALLY LOOKING AT THE 1813 01:06:09,744 --> 01:06:10,411 ASSOCIATION OF THE ECONOMIC 1814 01:06:10,411 --> 01:06:12,247 BURDEN OF DISEASE WITH VARIOUS 1815 01:06:12,247 --> 01:06:17,252 ASPECTS OF EMOTIONAL WELL-BEING. 1816 01:06:17,252 --> 01:06:18,519 UNDER MECHANISM, THE MECHANISM 1817 01:06:18,519 --> 01:06:20,588 BY WHICH THE ECONOMIC BURDEN OF 1818 01:06:20,588 --> 01:06:22,490 DISEASE AFFECTS, IMPACTS 1819 01:06:22,490 --> 01:06:23,124 EMOTIONAL WELL-BEING. 1820 01:06:23,124 --> 01:06:24,158 WE HAVE PROJECTS THAT HAVE 1821 01:06:24,158 --> 01:06:26,361 LOOKED AT DIFFERENT POPULATIONS 1822 01:06:26,361 --> 01:06:27,862 INCLUDING, FOR EXAMPLE, PARENTS 1823 01:06:27,862 --> 01:06:30,398 AND CHILDREN OR PATIENTS AND 1824 01:06:30,398 --> 01:06:32,400 CAREGIVERS, OR DIFFERENT 1825 01:06:32,400 --> 01:06:33,001 CONTEXTS. 1826 01:06:33,001 --> 01:06:34,569 DIFFERENT DISEASE CONTEXTS, 1827 01:06:34,569 --> 01:06:37,171 MAINLY STILL IN CANCER BECAUSE 1828 01:06:37,171 --> 01:06:38,506 THAT'S WHERE THE ECONOMIC BURDEN 1829 01:06:38,506 --> 01:06:40,742 OF DISEASE HAS BEEN STUDIED A 1830 01:06:40,742 --> 01:06:43,244 LOT BUT WE ALSO HAVE OTHER 1831 01:06:43,244 --> 01:06:44,746 DISEASES REPRESENTED. 1832 01:06:44,746 --> 01:06:45,880 AND DIFFERENT CONTEXTS FOR 1833 01:06:45,880 --> 01:06:48,349 EXAMPLE OF MARGINALIZED 1834 01:06:48,349 --> 01:06:50,918 POPULATIONS. 1835 01:06:50,918 --> 01:06:51,919 UNDER INTERVENTION WE DO HAVE 1836 01:06:51,919 --> 01:06:54,422 ONE PROJECT WHO STUDIED THE -- 1837 01:06:54,422 --> 01:06:57,058 STARTED TO ADDRESS -- STUDY HOW 1838 01:06:57,058 --> 01:06:58,793 TO ADDRESS AN INTERVENTION AND 1839 01:06:58,793 --> 01:07:02,630 LOOKING AT SOME -- LOOKING AT 1840 01:07:02,630 --> 01:07:05,733 THE IMPACT OF -- THE ROLE OF 1841 01:07:05,733 --> 01:07:06,734 ACCEPTANCE AND COMMITMENT 1842 01:07:06,734 --> 01:07:08,503 THERAPY. 1843 01:07:08,503 --> 01:07:10,571 WE ALSO HAVE FUNDED DISSERTATION 1844 01:07:10,571 --> 01:07:12,473 AWARDS AND WE ALSO HAVE THE 1845 01:07:12,473 --> 01:07:13,908 SMALL AWARDS, COLLABORATION 1846 01:07:13,908 --> 01:07:16,311 AWARDS THAT ARE TO SPEARHEAD THE 1847 01:07:16,311 --> 01:07:18,813 COLLABORATION ACROSS THE MEMBERS 1848 01:07:18,813 --> 01:07:20,348 LIKE SMALL AMOUNT OF MONEY TO 1849 01:07:20,348 --> 01:07:25,787 HELP THE COLLABORATIONS. 1850 01:07:25,787 --> 01:07:27,488 FOR OUR RESOURCES FOR AIM THREE, 1851 01:07:27,488 --> 01:07:30,458 WE DEVELOPED A WEBSITE WHERE WE 1852 01:07:30,458 --> 01:07:31,726 HAVE A LITERATURE DATABASE WHERE 1853 01:07:31,726 --> 01:07:34,996 WE HAVE GATHERED ALL THIS RECENT 1854 01:07:34,996 --> 01:07:36,597 LITERATURE ON BOTH THE ECONOMIC 1855 01:07:36,597 --> 01:07:38,766 BURDEN OF DISEASE AND EMOTIONAL 1856 01:07:38,766 --> 01:07:41,169 WELL-BEING, AND WE ALSO 1857 01:07:41,169 --> 01:07:43,137 DISSEMINATE THAT THROUGH OUR SAI 1858 01:07:43,137 --> 01:07:44,439 MAJJI, TWITTER AND LINKEDIN 1859 01:07:44,439 --> 01:07:44,706 ACCOUNTS. 1860 01:07:44,706 --> 01:07:47,342 WE DO HAVE A WEBINAR SERIES 1861 01:07:47,342 --> 01:07:49,377 WHERE WE INVITE RESEARCHERS WHO 1862 01:07:49,377 --> 01:07:50,978 ARE STUDYING THE ECONOMIC BURDEN 1863 01:07:50,978 --> 01:07:53,247 OF DISEASE OR STUDYING THE 1864 01:07:53,247 --> 01:07:54,582 EMOTIONAL WELL-BEING OR STUDYING 1865 01:07:54,582 --> 01:07:55,550 THE TWO TOGETHER. 1866 01:07:55,550 --> 01:07:58,653 AND ALSO HAVE WEBINARS THAT HAVE 1867 01:07:58,653 --> 01:08:00,221 DESCRIBED SOME OF THE RESOURCES, 1868 01:08:00,221 --> 01:08:06,661 FOR EXAMPLE, THESE DATA IN THE 1869 01:08:06,661 --> 01:08:09,964 U.S. -- DATA AND DR. ASMIT IN A 1870 01:08:09,964 --> 01:08:11,799 JOINT SEMINAR, TALKING ABOUT THE 1871 01:08:11,799 --> 01:08:13,000 HEALTH RETIREMENT SURVEY AND HOW 1872 01:08:13,000 --> 01:08:15,603 WE CAN USE THAT DATA TO -- IN 1873 01:08:15,603 --> 01:08:18,773 THIS AREA OF RESEARCH. 1874 01:08:18,773 --> 01:08:20,842 AS OF OUR ONGOING ACTIVITIES, WE 1875 01:08:20,842 --> 01:08:22,677 ARE FOCUSING NOW ON SOMERMAN EU 1876 01:08:22,677 --> 01:08:29,083 SCRIPTS. SOME NAN EU 1877 01:08:29,083 --> 01:08:30,118 MANUSCRIPTS IN THE CONTEXT OF 1878 01:08:30,118 --> 01:08:31,386 ECONOMIC BURDEN OF DISEASE. 1879 01:08:31,386 --> 01:08:32,987 THIS IS A RESULT OF OUR LAST 1880 01:08:32,987 --> 01:08:34,522 MEETING WITH OUR MEMBERS WHERE 1881 01:08:34,522 --> 01:08:36,758 WE HAD THOSE DISCUSSIONS, SO 1882 01:08:36,758 --> 01:08:38,159 WE'LL SUMMARIZE THAT. 1883 01:08:38,159 --> 01:08:40,128 WE'RE WORKING ON A SCOPING 1884 01:08:40,128 --> 01:08:42,096 REVIEW ON FINANCIAL TOXICITY, 1885 01:08:42,096 --> 01:08:43,765 WHICH IS ANOTHER SORT OF TERM IN 1886 01:08:43,765 --> 01:08:45,566 THE LITERATURE TO INDICATE 1887 01:08:45,566 --> 01:08:47,201 ECONOMIC BURDEN OF DISEASE. 1888 01:08:47,201 --> 01:08:49,404 AND ITS IMPACT -- WHAT WE MAY 1889 01:08:49,404 --> 01:08:50,338 KNOW FROM THE CURRENT LITERATURE 1890 01:08:50,338 --> 01:08:52,407 ON THE IMPACT ON EMOTIONAL 1891 01:08:52,407 --> 01:08:53,007 WELL-BEING. 1892 01:08:53,007 --> 01:08:55,676 AND THEN ONE OF OUR STUNT 1893 01:08:55,676 --> 01:08:57,979 COMMITTEE MEMBERS IS LEADING A 1894 01:08:57,979 --> 01:08:59,947 PAPER ON THE EFFECT OF THE 1895 01:08:59,947 --> 01:09:01,349 ECONOMIC BURDEN OF DISEASE ON 1896 01:09:01,349 --> 01:09:02,984 STRESS AND THEN THROUGH STRESS 1897 01:09:02,984 --> 01:09:03,985 ON PHYSICAL HEALTH. 1898 01:09:03,985 --> 01:09:06,554 WE ARE FUNDING NEW COLLABORATION 1899 01:09:06,554 --> 01:09:13,761 AWARDS THIS YEAR AND ON ON █ONE 1900 01:09:13,761 --> 01:09:14,829 SECONDARY DATA ANALYSIS COMING 1901 01:09:14,829 --> 01:09:17,398 THROUGH THE PIPELINE. 1902 01:09:17,398 --> 01:09:18,699 WE CONTINUE TO CREATE 1903 01:09:18,699 --> 01:09:19,767 OPPORTUNITIES FOR THIS LEARNING 1904 01:09:19,767 --> 01:09:22,603 RESEARCH THROUGH WEBINARS AND 1905 01:09:22,603 --> 01:09:23,271 SUPPORT EARLY CAREER 1906 01:09:23,271 --> 01:09:24,372 INVESTIGATORS WITH A 1907 01:09:24,372 --> 01:09:25,339 GRANT-WRITING RETREAT OR 1908 01:09:25,339 --> 01:09:27,074 INTENSIVE WORKSHOP. 1909 01:09:27,074 --> 01:09:28,309 THEN WE CONTINUE OUR 1910 01:09:28,309 --> 01:09:30,711 COLLABORATION WITH OTHERS, FOR 1911 01:09:30,711 --> 01:09:32,647 EXAMPLE, WE JUST HAD THE 1912 01:09:32,647 --> 01:09:34,749 RESEARCH SUMMIT WITH M3EWB AND 1913 01:09:34,749 --> 01:09:38,653 WE WILL PARTICIPATE IN THE 1914 01:09:38,653 --> 01:09:39,420 FAMNET FAMILY WELL-BEING 1915 01:09:39,420 --> 01:09:40,488 RESEARCH AGENDA SUMMIT IN THE 1916 01:09:40,488 --> 01:09:43,124 SUMMER. 1917 01:09:43,124 --> 01:09:45,893 FOR FUTURE STEPS, WE DO PLAN TO 1918 01:09:45,893 --> 01:09:47,094 SOLIDIFY THIS NETWORK. 1919 01:09:47,094 --> 01:09:54,669 WE ARE WORKING ON IDENTIFYING 1920 01:09:54,669 --> 01:09:55,303 A -- PROFESSIONAL ORGANIZATION 1921 01:09:55,303 --> 01:09:56,971 AND LOOK AT FUNDING TO CONTINUE 1922 01:09:56,971 --> 01:09:58,539 THE ANNUAL MEETINGS MAYBE 1923 01:09:58,539 --> 01:10:00,041 THROUGH THE R13 FUNDING 1924 01:10:00,041 --> 01:10:00,508 MECHANISM. 1925 01:10:00,508 --> 01:10:01,476 WE'VE BEEN TALKING ABOUT 1926 01:10:01,476 --> 01:10:03,511 EXPANDING THE RESEARCH WITH OUR 1927 01:10:03,511 --> 01:10:05,179 STEERING COMMITTEE. 1928 01:10:05,179 --> 01:10:08,115 WE WILL START DISCUSSION ON 1929 01:10:08,115 --> 01:10:12,753 PLANNING WI MULTI-SITE 1930 01:10:12,753 --> 01:10:13,387 COLLABORATIONS, WE'LL CONTINUE 1931 01:10:13,387 --> 01:10:15,156 FUNDING MECHANISMS FOR THAT, AND 1932 01:10:15,156 --> 01:10:17,992 ALSO THINKING ABOUT HOW TO 1933 01:10:17,992 --> 01:10:18,993 DISSEMINATE RESEARCH, AND AGAIN 1934 01:10:18,993 --> 01:10:19,927 WITH THE STEERING COMMITTEE 1935 01:10:19,927 --> 01:10:21,262 WE'VE BEEN TALKING ABOUT A 1936 01:10:21,262 --> 01:10:24,298 SPECIAL JOURNAL ISSUE THAT WE 1937 01:10:24,298 --> 01:10:25,466 MAY PURSUE WITH THIS. 1938 01:10:25,466 --> 01:10:27,902 BUT OVERALL IS TO BUILD ON THE 1939 01:10:27,902 --> 01:10:29,403 OPPORTUNITY GIVEN BY THIS 1940 01:10:29,403 --> 01:10:31,606 FUNDING MECHANISM TO CONTINUE 1941 01:10:31,606 --> 01:10:34,342 THIS WORK IN THIS AREA TO TACKLE 1942 01:10:34,342 --> 01:10:35,576 THIS IMPORTANT -- WHAT WE THINK 1943 01:10:35,576 --> 01:10:38,045 IS AN IMPORTANT FACTOR THAT 1944 01:10:38,045 --> 01:10:38,746 IMPACTS EMOTIONAL WELL-BEING. 1945 01:10:38,746 --> 01:10:41,115 THANK YOU. 1946 01:10:41,115 --> 01:10:48,089 [APPLAUSE] 1947 01:10:48,089 --> 01:10:49,824 SORRY, WE HAVE SOME SLIDES LEFT, 1948 01:10:49,824 --> 01:10:55,463 EXTRA SLIDES. 1949 01:10:55,463 --> 01:10:56,864 >> GOOD MORNING. 1950 01:10:56,864 --> 01:10:59,867 I'M WENDY ALONG WITH MELISSA 1951 01:10:59,867 --> 01:11:02,503 EPEL, WE LEAD THE NEW B NETWORK 1952 01:11:02,503 --> 01:11:12,914 OUT OF UC SAN FRANCISCO. 1953 01:11:35,970 --> 01:11:37,905 SORRY ABOUT THAT. 1954 01:11:37,905 --> 01:11:38,906 MELISSA AND I WILL BOTH BE 1955 01:11:38,906 --> 01:11:39,540 PRESENTING TODAY. 1956 01:11:39,540 --> 01:11:40,908 I JUST WANT TO ACKNOWLEDGE, WE 1957 01:11:40,908 --> 01:11:44,312 RUN THIS NETWORK ALONG WITH OUR 1958 01:11:44,312 --> 01:11:50,651 COINVESTIGATORS, ALONG WITH A 1959 01:11:50,651 --> 01:11:52,286 TERRIFIC GROUP OF POSTDOCS AND 1960 01:11:52,286 --> 01:11:55,523 ADMINISTRATORS. 1961 01:11:55,523 --> 01:11:57,325 GIVEN OUR SPECIFIC AREA OF 1962 01:11:57,325 --> 01:12:01,062 EXPERTISE, OUR NETWORK IS 1963 01:12:01,062 --> 01:12:02,797 FOCUSED ON BIOLOGICAL MECHANISMS 1964 01:12:02,797 --> 01:12:04,732 THAT LINK EMOTIONAL WELL-BEING 1965 01:12:04,732 --> 01:12:10,271 TO HEALTH, AND OUR AIMS INCLUDE 1966 01:12:10,271 --> 01:12:13,274 FUNDING STUDIES, PILOT STUDIES 1967 01:12:13,274 --> 01:12:15,109 TO DIVE DEEPLY INTO THOSE 1968 01:12:15,109 --> 01:12:16,310 MECHANISMS THAT LINK EMOTIONAL 1969 01:12:16,310 --> 01:12:18,312 WELL-BEING AND HEALTH, FUNDING, 1970 01:12:18,312 --> 01:12:20,982 INTERVENTION RESEARCH ON NOVEL 1971 01:12:20,982 --> 01:12:22,083 MECHANISMS, AND HELPING 1972 01:12:22,083 --> 01:12:23,517 DISSEMINATE AND CREATE 1973 01:12:23,517 --> 01:12:24,652 REPOSITORIES. 1974 01:12:24,652 --> 01:12:27,221 SOME OF OUR ACCOMPLISHMENTS TO 1975 01:12:27,221 --> 01:12:29,757 DATE INCLUDE FUNDING SCHOLARS TO 1976 01:12:29,757 --> 01:12:32,360 TAKE OUR HARMONIZED EMOTIONAL 1977 01:12:32,360 --> 01:12:33,761 WELL-BEING MEASURES FROM LARGE 1978 01:12:33,761 --> 01:12:36,631 SCALE STUDIES LIKE HRS AND 1979 01:12:36,631 --> 01:12:39,000 LOOKING SERIOUSLY AT HOW 1980 01:12:39,000 --> 01:12:40,501 BIOLOGICAL MECHANISMS MIGHT LINK 1981 01:12:40,501 --> 01:12:42,570 EMOTIONAL WELL-BEING TO HEALTH 1982 01:12:42,570 --> 01:12:44,472 ALONG THE LIFESPAN. 1983 01:12:44,472 --> 01:12:46,941 WE'VE ALSO CONDUCTED WEBINARS ON 1984 01:12:46,941 --> 01:12:49,076 BIOLOGICAL PROCESSES THAT 1985 01:12:49,076 --> 01:12:50,111 MELISSA IS GOING TO TELL YOU A 1986 01:12:50,111 --> 01:12:52,980 LITTLE BIT ABOUT, SUPPORTING 1987 01:12:52,980 --> 01:12:58,719 FUNDING FO FOR EMOTIONAL WELL-BG 1988 01:12:58,719 --> 01:13:00,554 AND PHYSICAL HEALTH AND FUNDING 1989 01:13:00,554 --> 01:13:01,555 FOR NOVEL INTERVENTIONS. 1990 01:13:01,555 --> 01:13:02,623 WE ALSO HAVE PUBLISHED A CODE 1991 01:13:02,623 --> 01:13:03,758 BOOK ON THE HEALTH AND 1992 01:13:03,758 --> 01:13:06,193 RETIREMENT STUDY TO HELP PEOPLE 1993 01:13:06,193 --> 01:13:08,462 TAKE THOSE HARMONIZED DATA AND 1994 01:13:08,462 --> 01:13:09,363 ANALYZE THEM AND YOU'LL HEAR A 1995 01:13:09,363 --> 01:13:10,698 LITTLE BIT ABOUT AN EXCITING 1996 01:13:10,698 --> 01:13:12,099 PROJECT CALLED BIG JOY. 1997 01:13:12,099 --> 01:13:13,434 I WANTED TO TELL YOU A LITTLE 1998 01:13:13,434 --> 01:13:15,236 BIT ABOUT ONE OF THE STUDIES 1999 01:13:15,236 --> 01:13:18,139 THAT WE FUNDED THAT WAS LOOKING 2000 01:13:18,139 --> 01:13:20,841 AT NOVEL INTERVENTIONS TO 2001 01:13:20,841 --> 01:13:22,443 IMPROVE EMOTIONAL WELL-BEING. 2002 01:13:22,443 --> 01:13:25,046 AND THAT INCLUDES A STUDY THAT'S 2003 01:13:25,046 --> 01:13:26,847 LOOKING AT STIMULATION OF THE 2004 01:13:26,847 --> 01:13:27,548 VAGUS NERVE. 2005 01:13:27,548 --> 01:13:29,116 SO THE VAGUS NERVE IS THE 2006 01:13:29,116 --> 01:13:31,218 LARGEST NERVE IN OUR BODY, 2007 01:13:31,218 --> 01:13:32,787 STIMULATES JUST ABOUT -- 2008 01:13:32,787 --> 01:13:34,021 INNERVATES EVERY MAJOR ORGAN AND 2009 01:13:34,021 --> 01:13:36,090 THERE'S TONS OF STUDIES THAT 2010 01:13:36,090 --> 01:13:38,559 LOOK AT CORRELATIONAL DATA 2011 01:13:38,559 --> 01:13:40,561 LINKING THE VAGUS NERVE TO 2012 01:13:40,561 --> 01:13:42,530 EMOTIONAL WELL-BEING OUTCOMES. 2013 01:13:42,530 --> 01:13:43,931 YOU CAN STIMULATE THE VAGUS 2014 01:13:43,931 --> 01:13:44,632 NERVE THROUGH THE EAR. 2015 01:13:44,632 --> 01:13:49,970 SO IN ONE STUDY, WHERE WE FUNDED 2016 01:13:49,970 --> 01:13:52,506 PARK AND GUEVARRA, THEY ARE 2017 01:13:52,506 --> 01:13:55,342 STIMULATING THE VAGUS NERVE AND 2018 01:13:55,342 --> 01:13:57,178 LOOKING AT HOW THAT MIGHT 2019 01:13:57,178 --> 01:14:02,883 IMPROVE SOCIAL CONNECTION USING 2020 01:14:02,883 --> 01:14:04,952 SYNCHRONY AS PRIMARY OUTCOME. 2021 01:14:04,952 --> 01:14:06,520 POTENTIALLY DIRECTLY IMPLICATING 2022 01:14:06,520 --> 01:14:08,422 THE VAGUS NERVE IN EMOTIONAL 2023 01:14:08,422 --> 01:14:12,193 WELL-BEING. 2024 01:14:12,193 --> 01:14:13,661 WE'VE ALSO DONE QUITE A BIT OF 2025 01:14:13,661 --> 01:14:15,763 PUBLISHING ALONG THE LINES OF 2026 01:14:15,763 --> 01:14:18,799 EMOTIONAL WELL-BEING CONSTRUCTS 2027 01:14:18,799 --> 01:14:21,135 LIKE AWE, HOW IT'S RELATED TO 2028 01:14:21,135 --> 01:14:23,771 PHYSICAL HEALTH, OPTIMISM, AND A 2029 01:14:23,771 --> 01:14:27,808 REALLY EXCITING STUDY ON DEEP 2030 01:14:27,808 --> 01:14:28,242 BREATHS. 2031 01:14:28,242 --> 01:14:29,877 ONE THAT I THINK NICELY 2032 01:14:29,877 --> 01:14:30,845 CHARACTERIZES OUR UNIQUE 2033 01:14:30,845 --> 01:14:33,347 APPROACH IS A PAPER BY PARK IN 2034 01:14:33,347 --> 01:14:34,849 WHICH SHE LOOKED AT SOME DATA 2035 01:14:34,849 --> 01:14:37,752 FROM A STUDY CALLED MY BP LAB. 2036 01:14:37,752 --> 01:14:42,656 THIS LOOKED AT MORE THAN 14,000 2037 01:14:42,656 --> 01:14:44,391 PEOPLE FOR MORE THAN 130,000 2038 01:14:44,391 --> 01:14:46,961 DAILY REPORTS AND LOOKED AT THE 2039 01:14:46,961 --> 01:14:49,163 EXPERIENCE OF POSITIVE AND 2040 01:14:49,163 --> 01:14:52,566 NEGATIVE EMOTION, HIGH OR LOW 2041 01:14:52,566 --> 01:14:53,134 AROUSAL AND BLOOD PRESSURE. 2042 01:14:53,134 --> 01:14:54,735 WHAT SHE FOUND IS THAT WHEN YOU 2043 01:14:54,735 --> 01:14:59,974 ASK PEOPLE IN THEIR DAILY LIFE 2044 01:14:59,974 --> 01:15:01,408 WHAT EMOTIONS THEY'RE FEELING, 2045 01:15:01,408 --> 01:15:02,376 ABOUT 80% OF THE TIME THEY 2046 01:15:02,376 --> 01:15:05,346 REPORT POSITIVE EMOTIONS. 2047 01:15:05,346 --> 01:15:06,614 AS YOU AGE AND CONSISTENT WITH 2048 01:15:06,614 --> 01:15:07,715 OTHER LITERATURE, YOU SEE AS 2049 01:15:07,715 --> 01:15:09,216 PEOPLE AGE, THEY REPORT MORE 2050 01:15:09,216 --> 01:15:10,484 POSITIVE EMOTION. 2051 01:15:10,484 --> 01:15:12,453 SHE ALSO HIGHLIGHTED SOME DATA 2052 01:15:12,453 --> 01:15:15,055 SHOWING THAT AS YOU AGE, THE LOW 2053 01:15:15,055 --> 01:15:17,458 AROUSAL POSITIVE EMOTIONS ARE 2054 01:15:17,458 --> 01:15:18,759 ASSOCIATED WITH LOWER BLOOD 2055 01:15:18,759 --> 01:15:19,360 PRESSURE. 2056 01:15:19,360 --> 01:15:22,596 SO ALLOWS US TO THINK OF 2057 01:15:22,596 --> 01:15:24,999 INTERVENTIONS TO POTENTIALLY 2058 01:15:24,999 --> 01:15:26,634 IMPROVE HEALTH FOR OLDER PEOPLE. 2059 01:15:26,634 --> 01:15:31,172 WITH THAT, I'M GOING TO HAND IT 2060 01:15:31,172 --> 01:15:34,175 OVER. 2061 01:15:34,175 --> 01:15:39,780 >> SO MUCH -- STRESS AND TRAUMA, 2062 01:15:39,780 --> 01:15:41,348 WE NEED TO STUDY THEM BOTH, WE 2063 01:15:41,348 --> 01:15:42,082 MIX THEM UP. 2064 01:15:42,082 --> 01:15:52,593 AS WENDY SAID, I'M LUCKY TO BE 2065 01:15:59,600 --> 01:16:01,168 HER NPI, WE HAVE DIFFERENT 2066 01:16:01,168 --> 01:16:01,802 SKILLSETS. 2067 01:16:01,802 --> 01:16:02,703 OKAY. 2068 01:16:02,703 --> 01:16:06,874 SO I WANTED TO JUST BRIEFLY GO 2069 01:16:06,874 --> 01:16:08,075 THROUGH WHY WE'RE SO EXCITED 2070 01:16:08,075 --> 01:16:09,543 ABOUT OUR NETWORK. 2071 01:16:09,543 --> 01:16:13,514 WE WERE FUNDED TO EXAMINE THE 2072 01:16:13,514 --> 01:16:14,315 PHYSIOLOGICAL AND BEHAVIORAL 2073 01:16:14,315 --> 01:16:16,717 PATHWAYS OF EMOTIONAL 2074 01:16:16,717 --> 01:16:17,985 WELL-BEING, AND WE HAVE BEEN 2075 01:16:17,985 --> 01:16:19,320 OBSESSED FOR A WHILE WITH THIS 2076 01:16:19,320 --> 01:16:22,556 QUESTION OF WHAT IS POSITIVE 2077 01:16:22,556 --> 01:16:23,557 HEALTH, WHAT'S POSITIVE 2078 01:16:23,557 --> 01:16:24,658 PHYSIOLOGY, HOW DO WE MEASURE 2079 01:16:24,658 --> 01:16:26,927 IT, WHAT PARADIGM, EXPERIMENTAL 2080 01:16:26,927 --> 01:16:29,096 PARADIGMS WILL REVEAL THE BODY'S 2081 01:16:29,096 --> 01:16:31,899 RESTORATIVE CAPACITY FOR 2082 01:16:31,899 --> 01:16:34,034 HEALING, RESILIENCE, AND 2083 01:16:34,034 --> 01:16:34,535 REPARATION. 2084 01:16:34,535 --> 01:16:36,537 SO IT'S VERY CONSISTENT WITH THE 2085 01:16:36,537 --> 01:16:41,308 WHOLE PERSON APPROACH, TH THAT I 2086 01:16:41,308 --> 01:16:42,576 IS TAKING. 2087 01:16:42,576 --> 01:16:44,144 WE DEVELOPED AN ARC OF THREE 2088 01:16:44,144 --> 01:16:45,546 WORKSHOPS. 2089 01:16:45,546 --> 01:16:47,014 THE FIRST TWO ARE WHAT DO WE 2090 01:16:47,014 --> 01:16:48,315 ALREADY KNOW, AND THIS THIRD ONE 2091 01:16:48,315 --> 01:16:50,451 THAT WE'RE PLANNING, WE'RE 2092 01:16:50,451 --> 01:16:52,019 INVITING INPUT OF YLDZ BECAUSE 2093 01:16:52,019 --> 01:16:57,858 IDEAS BECAUSEWE'RE LOOKING FOR S 2094 01:16:57,858 --> 01:16:58,826 OF PHYSIOLOGY. 2095 01:16:58,826 --> 01:17:01,128 THE FIRST WORKSHOP WAS 2096 01:17:01,128 --> 01:17:02,563 REACTIVITY AND RECOVERY AS WELL 2097 01:17:02,563 --> 01:17:05,633 AS STATIC, MORE STABLE MEASURES 2098 01:17:05,633 --> 01:17:08,602 THAT MIGHT REFLECT THIS INNATE 2099 01:17:08,602 --> 01:17:09,370 POSITIVE HEALTH. 2100 01:17:09,370 --> 01:17:10,738 NOT RISK FACTORS FOR DISEASE, 2101 01:17:10,738 --> 01:17:12,172 BUT MORE HEALING CAPACITY. 2102 01:17:12,172 --> 01:17:13,774 SO THIS WAS -- WENDY RAN THIS 2103 01:17:13,774 --> 01:17:16,277 ONE ON PSYCHOPHYSIOLOGY. 2104 01:17:16,277 --> 01:17:18,913 OUR SECOND ONE WAS ON BLOOD 2105 01:17:18,913 --> 01:17:20,581 BASED MARKERS. 2106 01:17:20,581 --> 01:17:23,183 SOCIAL GENOMICS, IMMUNE SYSTEM, 2107 01:17:23,183 --> 01:17:23,517 MITOCHONDRIA. 2108 01:17:23,517 --> 01:17:25,152 SO THESE WERE FASCINATING, WE 2109 01:17:25,152 --> 01:17:27,254 HAVE THESE ON OUR WEBSITE, WE'D 2110 01:17:27,254 --> 01:17:28,722 LOVE PEOPLE TO USE THESE AS A 2111 01:17:28,722 --> 01:17:30,257 RESOURCE. 2112 01:17:30,257 --> 01:17:32,059 BUT THE THIRD ONE, WE'RE LOOKING 2113 01:17:32,059 --> 01:17:33,661 AT SYSTEMS THAT HAVEN'T BEEN 2114 01:17:33,661 --> 01:17:37,798 EXAMINED IN A CONTEXT OF LOOKING 2115 01:17:37,798 --> 01:17:39,466 AT RESTORATION AND REPARATIVE 2116 01:17:39,466 --> 01:17:41,001 CAPACITY AND HEALTH, SO WE'RE 2117 01:17:41,001 --> 01:17:43,904 LOOKING AT DNA REPAIR, 2118 01:17:43,904 --> 01:17:45,539 MICROBIOME, DEEP SLEEP 2119 01:17:45,539 --> 01:17:47,741 MECHANISMS, NEURAL PATHWAYS, AND 2120 01:17:47,741 --> 01:17:48,409 BIG QUESTION MARK. 2121 01:17:48,409 --> 01:17:49,610 SO WE'D LOVE IDEAS THERE. 2122 01:17:49,610 --> 01:17:50,711 WE'RE STILL PLANNING OUR 2123 01:17:50,711 --> 01:17:52,913 SPEAKERS FOR AN EARLY NOVEMBER 2124 01:17:52,913 --> 01:17:56,050 SAN FRANCISCO WORKSHOP. 2125 01:17:56,050 --> 01:17:59,553 ANOTHER ONE OF OUR AIMS IS TO 2126 01:17:59,553 --> 01:18:01,889 HELP THESE POPULATION-BASED 2127 01:18:01,889 --> 01:18:03,657 STUDIES THAT NIA HAS INVESTED SO 2128 01:18:03,657 --> 01:18:06,560 MUCH IN CREATING AND FOLLOWING, 2129 01:18:06,560 --> 01:18:08,329 INCORPORATE BETTER MEASURES OF 2130 01:18:08,329 --> 01:18:09,663 EMOTIONAL WELL-BEING. 2131 01:18:09,663 --> 01:18:12,232 AND SO HERE WE'RE MEETING WITH 2132 01:18:12,232 --> 01:18:16,070 THE LEADERS OF THE MEASUREMENT 2133 01:18:16,070 --> 01:18:18,172 CORE OF ALL OF THESE COUNTRIES 2134 01:18:18,172 --> 01:18:21,742 IN LIKE 30 DIFFERENT STUDIES, 2135 01:18:21,742 --> 01:18:23,744 AND THROUGH EXPERT CONSENSUS, 2136 01:18:23,744 --> 01:18:25,279 THROUGH POLLING, THROUGH ZOOM 2137 01:18:25,279 --> 01:18:27,114 DISCUSSION, WE CAME UP WITH A 2138 01:18:27,114 --> 01:18:28,315 TOP PRIORITY LIST OF MEASURES, 2139 01:18:28,315 --> 01:18:30,718 BOTH FOR STRESS, TRAUMA AND 2140 01:18:30,718 --> 01:18:31,585 WELL-BEING. 2141 01:18:31,585 --> 01:18:32,720 SO FOR EXAMPLE, FOR WELL-BEING, 2142 01:18:32,720 --> 01:18:34,154 WHAT ROSE TO THE TOP WERE 2143 01:18:34,154 --> 01:18:39,927 MEASURES OF HOPE, OPTIMISM, 2144 01:18:39,927 --> 01:18:43,397 FLOURISHING, SOCIAL WELL-BEING, 2145 01:18:43,397 --> 01:18:44,064 AND GRATITUDE. 2146 01:18:44,064 --> 01:18:47,801 AND SO WE'RE REALLY HOPING, YOU 2147 01:18:47,801 --> 01:18:49,103 CAN'T BOSS AROUND PIs BUT 2148 01:18:49,103 --> 01:18:51,171 WE'RE HOPING THEY'LL INCORPORATE 2149 01:18:51,171 --> 01:18:51,805 THESE MEASURES, ESPECIALLY IN 2150 01:18:51,805 --> 01:18:53,741 THE NEW DEVELOPING STUDIES. 2151 01:18:53,741 --> 01:18:56,477 WE HAVE HAD THE JOY OF FUNDING 2152 01:18:56,477 --> 01:18:58,846 AMAZING SCHOLARS FOR THEIR WORK, 2153 01:18:58,846 --> 01:19:00,647 BOTH IN SECONDARY ANALYSES OF 2154 01:19:00,647 --> 01:19:02,149 THESE POPULATION BASED HEALTH 2155 01:19:02,149 --> 01:19:04,651 STUDIES WHERE THEY'RE USING THE 2156 01:19:04,651 --> 01:19:06,353 HARMONIZED DATA THAT WE'VE 2157 01:19:06,353 --> 01:19:07,621 HELPED ORGANIZE OR EMOTIONAL 2158 01:19:07,621 --> 01:19:09,189 WELL-BEING OR THEY'RE RUNNING -- 2159 01:19:09,189 --> 01:19:11,992 OR THESE ARE PEOPLE WHO GOT THE 2160 01:19:11,992 --> 01:19:16,397 TUITION SCHOLARSHIP TO ATTEND 2161 01:19:16,397 --> 01:19:17,664 THE POSITIVE HEALTH SUMMER 2162 01:19:17,664 --> 01:19:18,365 COURSE. 2163 01:19:18,365 --> 01:19:19,600 SO WE JUST WANTED TO SHOW YOU 2164 01:19:19,600 --> 01:19:23,504 ALL THESE HAPPY PEOPLE. 2165 01:19:23,504 --> 01:19:26,073 IN TERMS OF ONGOING ACTIVITY, WE 2166 01:19:26,073 --> 01:19:27,941 ARE HOLDING A WEBINAR APRIL 2ND 2167 01:19:27,941 --> 01:19:30,611 WHICH IS A FABULOUS OPPORTUNITY 2168 01:19:30,611 --> 01:19:32,279 FOR POSTDOCS AND TRAINEES WHO 2169 01:19:32,279 --> 01:19:33,814 WANT TO GET THEIR HANDS ON THIS 2170 01:19:33,814 --> 01:19:34,048 DATA. 2171 01:19:34,048 --> 01:19:36,750 IT'S A GUIDE TO HOW TO LOOK AT 2172 01:19:36,750 --> 01:19:38,352 HARMONIZED DATA ACROSS MANY 2173 01:19:38,352 --> 01:19:40,621 COUNTRIES, AND WE ALSO ARE 2174 01:19:40,621 --> 01:19:42,089 FEATURING THREE OF OUR YOUNG 2175 01:19:42,089 --> 01:19:44,625 SCHOLARS WHO WE'VE AWARDED TO DO 2176 01:19:44,625 --> 01:19:46,126 SECONDARY ANALYSES WHO HAVE 2177 01:19:46,126 --> 01:19:47,127 REVEALED CROSS COUNTRY 2178 01:19:47,127 --> 01:19:48,996 COMPARISONS LOOKING AT OUTCOMES 2179 01:19:48,996 --> 01:19:51,298 SUCH AS BLOOD PRESSURE, 2180 01:19:51,298 --> 01:20:00,941 INFLAMMATION AND MORTALITY. 2181 01:20:00,941 --> 01:20:04,545 OUR EXECUTIVE DIRECTOR OF OUR 2182 01:20:04,545 --> 01:20:06,447 NETWORK HAS BEEN AN EXPERT ON 2183 01:20:06,447 --> 01:20:07,381 EMOTIONAL WELL-BEING AND LEADING 2184 01:20:07,381 --> 01:20:08,782 THE GREATER GOOD SCIENCE CENTER 2185 01:20:08,782 --> 01:20:09,783 RESEARCH PROGRAM. 2186 01:20:09,783 --> 01:20:15,923 AND SO SHE HAS DEVELOPED -- IN 2187 01:20:15,923 --> 01:20:21,395 DEVELOPMENT I IS A DATABASE OF 2188 01:20:21,395 --> 01:20:22,062 POSITIVE WELL-BEING 2189 01:20:22,062 --> 01:20:23,130 INTERVENTIONS THAT HAVE BEEN 2190 01:20:23,130 --> 01:20:23,397 VALIDATED. 2191 01:20:23,397 --> 01:20:24,698 WOULDN'T IT BE GREAT IF 2192 01:20:24,698 --> 01:20:28,102 RESEARCHERS DIDN'T HAVE TO GO 2193 01:20:28,102 --> 01:20:30,337 RE-CREATE THE WHEEL, THEY COULD 2194 01:20:30,337 --> 01:20:33,607 GO TO A WEBSITE AND CHOOSE 2195 01:20:33,607 --> 01:20:34,975 EMPIRICALLY REPORTED STUDIES AND 2196 01:20:34,975 --> 01:20:35,742 GET THE PROTOCOLS. 2197 01:20:35,742 --> 01:20:41,315 SO THAT'S WHAT SHE IS LEADING, 2198 01:20:41,315 --> 01:20:42,816 LASTLY, WE'RE FUNDING PILOT 2199 01:20:42,816 --> 01:20:43,617 INTERVENTION STUDIES. 2200 01:20:43,617 --> 01:20:46,086 HOW CAN WE MANIPULATE ASPECTS OF 2201 01:20:46,086 --> 01:20:48,455 EMOTIONAL WELL-BEING AND STUDY 2202 01:20:48,455 --> 01:20:50,023 IN A GRANULAR WAY THE 2203 01:20:50,023 --> 01:20:51,391 MECHANISMS, PSYCH COPHYSIOLOGY, 2204 01:20:51,391 --> 01:20:54,728 SOCIAL GENOMICS, AS WELL AS 2205 01:20:54,728 --> 01:20:56,230 NEURAL PATHWAYS OF REWARD AND 2206 01:20:56,230 --> 01:20:56,497 THREAT. 2207 01:20:56,497 --> 01:20:58,132 SO HERE ARE THREE OF OUR RECENT 2208 01:20:58,132 --> 01:20:58,832 INTERVENTION AWARDEES. 2209 01:20:58,832 --> 01:21:01,535 WE ARE SO EXCITED TO HEAR WHAT 2210 01:21:01,535 --> 01:21:02,069 THEY'RE LEARNING. 2211 01:21:02,069 --> 01:21:05,973 THEY'RE USING BOTH LI DIGITAL 2212 01:21:05,973 --> 01:21:06,673 METHODS AS WELL AS IN THE FIELD 2213 01:21:06,673 --> 01:21:07,708 INTERVENTION METHODS SUCH AS 2214 01:21:07,708 --> 01:21:11,678 WHAT IF WE TOLD SOMEONE TO BE AN 2215 01:21:11,678 --> 01:21:13,147 EXTROVERT AND HAVE A LOT OF 2216 01:21:13,147 --> 01:21:14,114 SOCIAL INTERACTIONS DURING THEIR 2217 01:21:14,114 --> 01:21:14,581 DAY. 2218 01:21:14,581 --> 01:21:17,618 AND HERE'S THE REPOSITORY. 2219 01:21:17,618 --> 01:21:21,488 SO WHAT'S NICE ABOUT THIS IS 2220 01:21:21,488 --> 01:21:23,390 THAT WE'RE TAKING FROM THE 2221 01:21:23,390 --> 01:21:25,125 GREATER GOOD IN ACTION WEBSITE 2222 01:21:25,125 --> 01:21:26,994 WHICH HAS AN INCREDIBLE VAST 2223 01:21:26,994 --> 01:21:28,328 ARRAY OF INTERVENTIONS AND 2224 01:21:28,328 --> 01:21:29,630 PULLING THOSE THAT ARE MOST 2225 01:21:29,630 --> 01:21:32,766 PROMISING AND MOST SUPPORTIVE. 2226 01:21:32,766 --> 01:21:35,269 SO LASTLY, OUR NEXT STEPS, 2227 01:21:35,269 --> 01:21:37,571 CONTINUE EVERYTHING WE JUST 2228 01:21:37,571 --> 01:21:38,472 DESCRIBED, CONTINUE FOSTERING 2229 01:21:38,472 --> 01:21:40,774 THE POPULATION-BASED STUDIES, 2230 01:21:40,774 --> 01:21:42,075 AND LASTLY, I JUST WANTED TO 2231 01:21:42,075 --> 01:21:48,081 MENTION OUR BIG JOY PROJECT. 2232 01:21:48,081 --> 01:21:51,051 WE HAVE LAUNCHED A DIGITAL 2233 01:21:51,051 --> 01:21:53,921 PLATFORM TO PROMOTE JOY THAT HAS 2234 01:21:53,921 --> 01:21:54,421 GONE VIRAL. 2235 01:21:54,421 --> 01:21:56,490 WE'RE VERY LUCKY WHEN THIS 2236 01:21:56,490 --> 01:22:00,360 HAPPENS, BUT WE HAVE ALMOST 2237 01:22:00,360 --> 01:22:02,496 100,000 PEOPLE ENROLLED IN THIS 2238 01:22:02,496 --> 01:22:04,198 ONE-WEEK INTERVENTION ACROSS 2239 01:22:04,198 --> 01:22:06,700 TERRITORIES AND COUNTRIES, OVER 2240 01:22:06,700 --> 01:22:07,801 200 TERRITORIES AND COUNTRIES. 2241 01:22:07,801 --> 01:22:09,603 THERE'S ONLY 200 COUNTRIES OR 2242 01:22:09,603 --> 01:22:13,507 SO, SO WHAT WE FOUND SO FAR IS 2243 01:22:13,507 --> 01:22:15,375 JUST IN A VERY CRUDE WAY, ASK 2244 01:22:15,375 --> 01:22:17,945 THE QUESTION OF, HOW DOES THIS 2245 01:22:17,945 --> 01:22:19,246 AFFECT PEOPLE'S EMOTIONAL 2246 01:22:19,246 --> 01:22:20,347 WELL-BEING OVER A WEEK? 2247 01:22:20,347 --> 01:22:21,348 AND IT'S JUST FIVE MINUTES IN 2248 01:22:21,348 --> 01:22:23,383 THE MORNING OF A PRACTICE, 2249 01:22:23,383 --> 01:22:25,586 GRATITUDE, COMPASSION, KINDNESS. 2250 01:22:25,586 --> 01:22:26,687 AND WHAT WE'RE REALLY EXCITED 2251 01:22:26,687 --> 01:22:30,257 TODAY DO IS TO LOOK HOW 2252 01:22:30,257 --> 01:22:31,458 INTERVENTIONS COMPARE FOR 2253 01:22:31,458 --> 01:22:34,695 IMMEDIATE POSITIVE AND NEGATIVE 2254 01:22:34,695 --> 01:22:37,531 AFFECT, HOW DOES IS IT MODERATED 2255 01:22:37,531 --> 01:22:40,367 BY INDIVIDUALS, SOCIAL 2256 01:22:40,367 --> 01:22:42,135 DEMOGRAPHIC ROUTES, COUNTRY 2257 01:22:42,135 --> 01:22:44,204 REGIONS, SOCIAL IDENTITIES. 2258 01:22:44,204 --> 01:22:47,608 SO DARWIN HAS BEEN OUR EWB 2259 01:22:47,608 --> 01:22:48,575 POSTDOC LEADING THIS, AND YOU 2260 01:22:48,575 --> 01:22:50,043 CAN SEE WE HAVE PRETTY 2261 01:22:50,043 --> 01:22:51,778 IMPRESSIVE EFFECT SIZES, MEDIUM 2262 01:22:51,778 --> 01:22:53,280 EFFECT SIZES FOR AN INCREASE 2263 01:22:53,280 --> 01:22:55,282 ACROSS THIS LARGE SAMPLE FOR 2264 01:22:55,282 --> 01:22:56,383 EMOTIONAL WELL-BEING AND 2265 01:22:56,383 --> 01:22:57,718 FLOURISHING, POSITIVE EMOTIONS, 2266 01:22:57,718 --> 01:22:59,519 AND THIS INTERESTING ITEM THAT 2267 01:22:59,519 --> 01:23:00,153 MEASURES HOW MUCH DO YOU FEEL 2268 01:23:00,153 --> 01:23:02,889 THAT YOU CAN CONTROL YOUR LEVEL 2269 01:23:02,889 --> 01:23:04,124 OF HAPPINESS EACH DAY. 2270 01:23:04,124 --> 01:23:05,792 SO THIS AGENCY. 2271 01:23:05,792 --> 01:23:08,228 AND THEN FOR HEALTH, WE'RE NOT 2272 01:23:08,228 --> 01:23:09,630 TARGETING HEALTH BUT WE MEASURED 2273 01:23:09,630 --> 01:23:11,231 IT AND IT PASSIVELY SEEMS TO BE 2274 01:23:11,231 --> 01:23:12,299 AFFECTING HEALTH WITH A VERY 2275 01:23:12,299 --> 01:23:15,702 SMALL OR SMALL EFFECT, AT LEAST 2276 01:23:15,702 --> 01:23:19,273 SELF-REPORTED HELP IN SLEEP 2277 01:23:19,273 --> 01:23:19,873 QUALITY. 2278 01:23:19,873 --> 01:23:21,675 OUR NEXT STEP IS TO ADD A 2279 01:23:21,675 --> 01:23:23,410 CONTROL GROUP AND ADD 2280 01:23:23,410 --> 01:23:23,710 BIOSENSORS. 2281 01:23:23,710 --> 01:23:24,011 THANK YOU. 2282 01:23:24,011 --> 01:23:34,187 [APPLAUSE] 2283 01:23:42,963 --> 01:23:45,132 >> GOOD MORNING. 2284 01:23:45,132 --> 01:23:55,842 SO VANKEE LIN IS NOW AT STANFORD 2285 01:23:56,410 --> 01:23:57,477 UNIVERSITY, WE'RE THE 2286 01:23:57,477 --> 01:24:00,347 CODIRECTORS OF THE NETWORK FOR 2287 01:24:00,347 --> 01:24:01,381 EMOTIONAL WELL-BEING AND BRAIN 2288 01:24:01,381 --> 01:24:01,615 AGING. 2289 01:24:01,615 --> 01:24:02,716 I JUST WANT TO SAY HOW PLEASED 2290 01:24:02,716 --> 01:24:07,220 WE ALL ARE ABOUT BEING HERE AND 2291 01:24:07,220 --> 01:24:08,955 WANT TO THANK, OF COURSE, ALL OF 2292 01:24:08,955 --> 01:24:11,058 OUR NIH PARTNERS AT THE 2293 01:24:11,058 --> 01:24:11,992 DIFFERENT INSTITUTES AND CENTERS 2294 01:24:11,992 --> 01:24:13,927 WHO ARE INVOLVED. 2295 01:24:13,927 --> 01:24:19,299 IT'S BEEN A GREAT EXPERIENCE, 2296 01:24:19,299 --> 01:24:21,034 FACILITATED GREATLY BY 2297 01:24:21,034 --> 01:24:22,336 DR. JANINE SIMMONS, SCIENTIFIC 2298 01:24:22,336 --> 01:24:22,869 OFFICER. 2299 01:24:22,869 --> 01:24:23,870 SO THAT'S WONDERFUL. 2300 01:24:23,870 --> 01:24:25,405 I'M GOING TO VERY QUICKLY TALK 2301 01:24:25,405 --> 01:24:28,008 ABOUT THE BIG PICTURE OVERALL 2302 01:24:28,008 --> 01:24:31,244 GOALS AND AIMS, ONE OF THE FIRST 2303 01:24:31,244 --> 01:24:33,280 OF OUR AIMS, AND HAND IT OVER TO 2304 01:24:33,280 --> 01:24:35,449 DR. WONG TO GO INTO GREATER 2305 01:24:35,449 --> 01:24:40,020 DETAIL ABOUT THROUGH THE OTHER 2306 01:24:40,020 --> 01:24:41,488 THREE AIMS, HE WILL TOUCH ON THE 2307 01:24:41,488 --> 01:24:43,023 STORY OF -- THE FOCUS OF THE NEW 2308 01:24:43,023 --> 01:24:44,257 BRAIN AGING CENTER HAS EVOLVED 2309 01:24:44,257 --> 01:24:45,826 OVER TIME. 2310 01:24:45,826 --> 01:24:46,960 OUR OVERALL GOAL AS YOU SEE HERE 2311 01:24:46,960 --> 01:24:49,029 IS TO CONDUCT MECHANISTIC 2312 01:24:49,029 --> 01:24:50,330 RESEARCH ON THE ROLE OF 2313 01:24:50,330 --> 01:24:52,899 EMOTIONAL WELL-BEING IN HEALTHY 2314 01:24:52,899 --> 01:24:53,633 AGING. 2315 01:24:53,633 --> 01:24:54,835 IDENTIFYING TESTING MECHANISMS 2316 01:24:54,835 --> 01:24:57,237 BY WHICH BRAIN AGING INFLUENCES 2317 01:24:57,237 --> 01:25:07,347 EWB, AND HOW EWB RES RECIPROCALY 2318 01:25:07,347 --> 01:25:09,015 INFLUENCES RISK FOR AND 2319 01:25:09,015 --> 01:25:09,549 PROGRESSION OF ALZHEIMER'S 2320 01:25:09,549 --> 01:25:13,153 DISEASE AND RELATED DEMENTIAS 2321 01:25:13,153 --> 01:25:14,788 WITH A CROSS-SPECIES 2322 01:25:14,788 --> 01:25:21,728 APPROACHMENT OUR SAPPROACH.OUR E 2323 01:25:21,728 --> 01:25:23,797 REPOSITORY DEVELOPMENT, PILOT 2324 01:25:23,797 --> 01:25:24,464 PROJECT GRANTS. 2325 01:25:24,464 --> 01:25:26,733 WITH REGARD TO INVESTIGATOR 2326 01:25:26,733 --> 01:25:28,101 ENGAGEMENT, I WILL TOUCH ON 2327 01:25:28,101 --> 01:25:32,839 THAT, THE FIRST IS TO BUILD AN 2328 01:25:32,839 --> 01:25:34,174 INTERUNIVERSE IT AND 2329 01:25:34,174 --> 01:25:34,975 TRANSDISCIPLINARY COLLABORATIVE 2330 01:25:34,975 --> 01:25:36,610 OF SENIOR AND JUNIOR 2331 01:25:36,610 --> 01:25:37,310 INVESTIGATORS INTERESTED IN THIS 2332 01:25:37,310 --> 01:25:38,278 AREA OF RESEARCH. 2333 01:25:38,278 --> 01:25:40,747 OUR EXECUTIVE COMMITTEE INVOLVED 2334 01:25:40,747 --> 01:25:45,986 FOLKS FROM URR AND STANFORD AS 2335 01:25:45,986 --> 01:25:47,387 WELL AS GROUP, YOU SEE SANTA 2336 01:25:47,387 --> 01:25:48,855 CRUZ AND JOHNS HOPKINS AND OVER 2337 01:25:48,855 --> 01:25:50,957 TIME THROUGH OUR PILOT PROJECT 2338 01:25:50,957 --> 01:25:52,159 PROGRAM IN PARTICULAR WE HAVE 2339 01:25:52,159 --> 01:25:53,660 INCORPORATED INVESTIGATORS FROM 2340 01:25:53,660 --> 01:25:56,229 A VARIETY OF OTHER UNIVERSITIES 2341 01:25:56,229 --> 01:25:59,800 AROUND THE UNITED STATES. 2342 01:25:59,800 --> 01:26:04,104 WE ALSO THEN HAVE HELD AN ANNUAL 2343 01:26:04,104 --> 01:26:05,505 NEW BRAIN AGING WORKSHOP THAT 2344 01:26:05,505 --> 01:26:07,441 HAS BEEN INTEGRATED FOR TWO 2345 01:26:07,441 --> 01:26:11,445 YEARS WITH THE SOCIETY FOR 2346 01:26:11,445 --> 01:26:12,345 NEUROSCIENCE ANNUAL MEETING AND 2347 01:26:12,345 --> 01:26:14,748 THEN FOR THE COMING YEAR, THE 2348 01:26:14,748 --> 01:26:16,049 ALZHEIMER'S ASSOCIATION 2349 01:26:16,049 --> 01:26:17,117 INTERNATIONAL CONFERENCE AS A 2350 01:26:17,117 --> 01:26:19,686 MEANS TO FIRST DISSEMINATE THE 2351 01:26:19,686 --> 01:26:23,256 VIEW, THE PERSPECTIVE, THE 2352 01:26:23,256 --> 01:26:25,492 FINDINGS OF NEW BRAIN AGING. 2353 01:26:25,492 --> 01:26:29,529 BUT ALSO AS A WAY TO CONTINUE TO 2354 01:26:29,529 --> 01:26:31,264 INCORPORATE OTHER JUNIOR 2355 01:26:31,264 --> 01:26:32,132 INVESTIGATORS AS WELL AS 2356 01:26:32,132 --> 01:26:34,768 ESTABLISHED INVESTIGATORS NOT 2357 01:26:34,768 --> 01:26:36,102 HERETOFORE INVOLVED WITH 2358 01:26:36,102 --> 01:26:37,304 EMOTIONAL WELL-BEING RESEARCH IN 2359 01:26:37,304 --> 01:26:37,671 THIS EFFORT. 2360 01:26:37,671 --> 01:26:39,940 TO DO THAT, WE HAVE, FOR 2361 01:26:39,940 --> 01:26:43,443 EXAMPLE, HELD A COMPETITIVE 2362 01:26:43,443 --> 01:26:46,813 TRAVEL FELLOWSHIP OVER TIME 2363 01:26:46,813 --> 01:26:48,148 WHICH HAS BROUGHT TOGETHER AT 2364 01:26:48,148 --> 01:26:52,219 THE SFN AND WILL AT AAIC A GROUP 2365 01:26:52,219 --> 01:26:56,223 OF REALLY REMARKABLE EARLY YEAR 2366 01:26:56,223 --> 01:26:59,226 FOLKS WHO THEN ENGAGE IN A 2367 01:26:59,226 --> 01:27:00,594 MENTORED EXPERIENCE AT THE 2368 01:27:00,594 --> 01:27:01,995 MEETING AND THEN FOR THE 2369 01:27:01,995 --> 01:27:04,598 FOLLOWING YEAR ON A REGULAR 2370 01:27:04,598 --> 01:27:06,366 BASIS RECONVENE WITH US 2371 01:27:06,366 --> 01:27:07,434 VIRTUALLY TO REVIEW THE PROGRESS 2372 01:27:07,434 --> 01:27:10,704 OF THEIR OWN WORK. 2373 01:27:10,704 --> 01:27:11,571 EXPERT CONSULTATION TO 2374 01:27:11,571 --> 01:27:12,639 INVESTIGATORS NEW TO THE STUDY 2375 01:27:12,639 --> 01:27:15,208 OF EW B AND BRAIN AGING, AGAIN, 2376 01:27:15,208 --> 01:27:16,910 THIS IS IN PART THROUGH OUR 2377 01:27:16,910 --> 01:27:17,878 MENTORING PROGRAM WITH EARLY 2378 01:27:17,878 --> 01:27:21,448 CAREER INVESTIGATORS, BUT ALSO 2379 01:27:21,448 --> 01:27:24,985 THROUGH THE AVAILABILITY OF NEW 2380 01:27:24,985 --> 01:27:26,786 BRAIN AGING SENIOR INVESTIGATORS 2381 01:27:26,786 --> 01:27:28,421 TO OTHERS WITH INTERESTS IN THE 2382 01:27:28,421 --> 01:27:31,992 FIELD, AND THROUGH THE 2383 01:27:31,992 --> 01:27:33,960 DEVELOPMENT OF AN OFFERING THE 2384 01:27:33,960 --> 01:27:35,061 QUARTERLY WEBINARS AS WELL AS 2385 01:27:35,061 --> 01:27:38,965 THE DEVELOPMENT OF A RESOURCE 2386 01:27:38,965 --> 01:27:40,567 REPOSITORY THAT WILL TELL YOU A 2387 01:27:40,567 --> 01:27:42,869 LITTLE BIT MORE ABOUT. 2388 01:27:42,869 --> 01:27:45,171 THIS IS OUR EXECUTIVE COMMITTEE, 2389 01:27:45,171 --> 01:27:47,140 AND THEN JUST BECAUSE A PICTURE 2390 01:27:47,140 --> 01:27:48,275 IS WORTH A THOUSAND WORDS COMING 2391 01:27:48,275 --> 01:27:51,177 BACK TO OUR EFFORT TO EXPAND THE 2392 01:27:51,177 --> 01:27:54,014 INTEREST OF THE FIELD, THIS IS A 2393 01:27:54,014 --> 01:27:59,185 NETWORK MAP THAT INDICATE 2394 01:27:59,185 --> 01:28:00,820 RELATIONSHIPS BETWEEN TWO 2395 01:28:00,820 --> 01:28:04,491 PERSONS BY CO-AUTHORING PAPERS, 2396 01:28:04,491 --> 01:28:06,226 COAPPLYING FOR FUNDING, 2397 01:28:06,226 --> 01:28:07,527 CONFERENCE PRESENTATIONS AND 2398 01:28:07,527 --> 01:28:09,129 MENTORED RELATIONSHIPS, WHAT IT 2399 01:28:09,129 --> 01:28:10,797 LOOKED LIKE IN YEAR ONE WITH THE 2400 01:28:10,797 --> 01:28:15,535 13 ORIGINAL FOLKS INVOLVED WITH 2401 01:28:15,535 --> 01:28:17,737 THE DIFFERENT COLORS INDICATING 2402 01:28:17,737 --> 01:28:19,339 INTERACTIONS THAT RELATE TO 2403 01:28:19,339 --> 01:28:20,006 HUMAN RESEARCH, ANIMAL RESEARCH 2404 01:28:20,006 --> 01:28:22,342 AND THEN CROSS-SPECIES RESEARCH, 2405 01:28:22,342 --> 01:28:23,910 AND THEN WHERE WE ARE FOUR YEARS 2406 01:28:23,910 --> 01:28:26,646 LATER WITH 69 INVOLVED 2407 01:28:26,646 --> 01:28:29,215 INVESTIGATORS OF WHICH 19 ARE 2408 01:28:29,215 --> 01:28:30,750 EARLY CAREER FOLKS. 2409 01:28:30,750 --> 01:28:34,187 IT'S KIND OF FUN TO SEE IT THAT 2410 01:28:34,187 --> 01:28:34,988 WAY, A BEGINNING SORT OF 2411 01:28:34,988 --> 01:28:36,790 INVESTIGATION AND I THINK WE CAN 2412 01:28:36,790 --> 01:28:37,924 DO ADDITIONAL ANALYSES ON TO 2413 01:28:37,924 --> 01:28:39,859 LOOK AT THE KINDS OF RESEARCH OR 2414 01:28:39,859 --> 01:28:40,627 INTERACTIONS AND RELATIONSHIPS 2415 01:28:40,627 --> 01:28:41,628 THAT ARE BEING DEVELOPED OVER 2416 01:28:41,628 --> 01:28:42,028 TIME. 2417 01:28:42,028 --> 01:28:44,230 AND WITH THAT, LET ME HAND IT 2418 01:28:44,230 --> 01:28:51,004 OVER TO DR. WONG. 2419 01:28:51,004 --> 01:28:51,438 >> THANK YOU. 2420 01:28:51,438 --> 01:28:52,572 I'M GOING TO CONTINUE TO TALK 2421 01:28:52,572 --> 01:28:55,241 ABOUT OUR FOLLOWING AIMS THAT WE 2422 01:28:55,241 --> 01:28:57,544 DEVELOPED TOGETHER AS A NETWORK. 2423 01:28:57,544 --> 01:29:01,615 SO THE AIM TWO IS REALLY TO 2424 01:29:01,615 --> 01:29:02,716 DEVELOP STRATEGIC PRIORITY 2425 01:29:02,716 --> 01:29:04,517 THROUGH FORMING SEVERAL WORK 2426 01:29:04,517 --> 01:29:06,686 GROUPS TO START WITH, WE 2427 01:29:06,686 --> 01:29:08,688 PARTICIPATE IN THIS NETWORK OF 2428 01:29:08,688 --> 01:29:13,326 NETWORK ACTIVITY WITH CRYSTAL 2429 01:29:13,326 --> 01:29:17,097 PARK IN THIS EWB DEFINITION, AND 2430 01:29:17,097 --> 01:29:18,431 SPECIFICALLY TO OUR NEW BRAIN 2431 01:29:18,431 --> 01:29:24,404 AGING CENTER, WE ALSO DEVELO 2432 01:29:24,404 --> 01:29:25,305 DEVELOPED -- BUILD ON THE 2433 01:29:25,305 --> 01:29:26,206 ORIGINAL DEFINITION AND 2434 01:29:26,206 --> 01:29:28,975 DEVELOPED ADDITIONAL CONCEPTUAL 2435 01:29:28,975 --> 01:29:32,178 FRAMEWORK, SO WE EMPHASIZE FOR 2436 01:29:32,178 --> 01:29:34,714 CROSS SPECIES STUDY REACTIVITY 2437 01:29:34,714 --> 01:29:37,384 AND REAPPRAISAL BASED MODEL TO 2438 01:29:37,384 --> 01:29:40,654 STUDY EWB MECHANISM AND CHANGES 2439 01:29:40,654 --> 01:29:42,222 IN BRAIN AGING AND OPERATIONALLY 2440 01:29:42,222 --> 01:29:45,358 WE ALSO DEVELOPED A FRAMEWORK 2441 01:29:45,358 --> 01:29:47,127 FOR COMPARABLE CROSS SPECIES 2442 01:29:47,127 --> 01:29:48,795 APPROACHES TO STUDY BRAIN 2443 01:29:48,795 --> 01:29:52,666 BEHAVIOR RELATIONSHIPS IN EWB. 2444 01:29:52,666 --> 01:29:54,601 LET ME ELABORATE A LITTLE BIT 2445 01:29:54,601 --> 01:29:57,671 MORE ON THESE TWO FRAME WORKS. 2446 01:29:57,671 --> 01:30:01,007 SO FOR THE CONCEPTUAL FRAMEWORK 2447 01:30:01,007 --> 01:30:03,410 TO ENSURE COMPARABLE STUDIES IN 2448 01:30:03,410 --> 01:30:07,580 ANIMAL AND HUMAN STUDIES, WE 2449 01:30:07,580 --> 01:30:09,149 SUGGEST TO RELATIVELY SIMPLIFY 2450 01:30:09,149 --> 01:30:11,017 THE EFFECTIVE STIMULI THAT ARE 2451 01:30:11,017 --> 01:30:15,689 USED FOR STUDY AND THE FOCUS ON 2452 01:30:15,689 --> 01:30:19,125 THE DIMENSIONAL FEATURES SUCH 2453 01:30:19,125 --> 01:30:20,660 AS -- AROUSAL, AND THE 2454 01:30:20,660 --> 01:30:23,563 LITERATURE ON THE RESPONSE OF 2455 01:30:23,563 --> 01:30:26,399 THE PHYSIOLOGICAL AND BEHAVIORAL 2456 01:30:26,399 --> 01:30:30,270 RESPONSE TO AFFECT THE STIMULI 2457 01:30:30,270 --> 01:30:31,971 OR EMOTIONAL ACTIVITY, THIS IS 2458 01:30:31,971 --> 01:30:33,206 RELATIVELY CONSISTENT. 2459 01:30:33,206 --> 01:30:36,810 WE CONSIDER THESE PROCESSES ARE 2460 01:30:36,810 --> 01:30:40,513 IMPORTANT COMPONENT OF THE 2461 01:30:40,513 --> 01:30:42,849 EXPERIENTIAL FEATURES OF EWB 2462 01:30:42,849 --> 01:30:44,417 MENTIONED IN THE NETWORK 2463 01:30:44,417 --> 01:30:47,353 DEFINITION OF EWB. 2464 01:30:47,353 --> 01:30:50,824 HERE WE ALSO PROPOSE TO FURTHER 2465 01:30:50,824 --> 01:30:53,059 EMPHASIZE THE REFLECTIVE -- THE 2466 01:30:53,059 --> 01:30:57,997 BRAIN PROCESSES WE NAMED THEM AS 2467 01:30:57,997 --> 01:30:59,699 REAPPRAISAL WE CONSIDER TO BE 2468 01:30:59,699 --> 01:31:01,501 RELATED TO REFLECTIVE ASPECT OF 2469 01:31:01,501 --> 01:31:03,403 EWB, SO THIS WILL INCLUDE 2470 01:31:03,403 --> 01:31:05,939 ELABORATION MEMORY ENCODING AND 2471 01:31:05,939 --> 01:31:06,639 RETRIEVAL AS WELL AS COGNITIVE 2472 01:31:06,639 --> 01:31:09,542 CONTROL. 2473 01:31:09,542 --> 01:31:11,377 TO STUDY THE NEURAL BRAIN 2474 01:31:11,377 --> 01:31:14,114 PROCESS UNDERLYING SUCH PROCESS, 2475 01:31:14,114 --> 01:31:16,449 WE REVIEW THE LITERATURE AND 2476 01:31:16,449 --> 01:31:21,454 EMPHASIZE THE RECENT STUDIES 2477 01:31:21,454 --> 01:31:24,090 HIGHLIGHTING A COMPARABLE 2478 01:31:24,090 --> 01:31:26,392 BRAINNET WORK TONNOLOGY FOR 2479 01:31:26,392 --> 01:31:27,861 EMOTION PROCESSING ACROSS 2480 01:31:27,861 --> 01:31:28,862 SPECIES. 2481 01:31:28,862 --> 01:31:31,998 AS CHARLES DARWIN NOTED YEARS -- 2482 01:31:31,998 --> 01:31:36,035 A LONG TIME AGO, ENSURE 2483 01:31:36,035 --> 01:31:37,170 ADAPTATION OF ANIMAL OR 2484 01:31:37,170 --> 01:31:38,538 INDIVIDUAL ORGANISM TO THE 2485 01:31:38,538 --> 01:31:39,839 ENVIRONMENT FOR IN TERMS OF 2486 01:31:39,839 --> 01:31:42,976 SURVIVAL AND REPRODUCTION, SO 2487 01:31:42,976 --> 01:31:44,778 THE DEVELOPMENTAL GENETICS AND 2488 01:31:44,778 --> 01:31:47,180 ANATOMY EMPHASIZED THE CONSERVED 2489 01:31:47,180 --> 01:31:50,450 TOPOLOGY ACROSS ANIMAL SPECIES 2490 01:31:50,450 --> 01:31:51,851 AND FUNCTIONAL CONNECTIVITY 2491 01:31:51,851 --> 01:31:53,486 ACTIVITIES ECK FA SIZE THAT KEY 2492 01:31:53,486 --> 01:31:54,888 NETWORKS SUCH AS A DEFAULT IN 2493 01:31:54,888 --> 01:31:57,090 THE SAVINGS NETWORK IN EMOTIONAL 2494 01:31:57,090 --> 01:31:57,657 REGULATION. 2495 01:31:57,657 --> 01:32:01,895 SO HOW DO WE STUDY BASED ON THIS 2496 01:32:01,895 --> 01:32:06,699 BASIC BLUEPRINT TO STUDY THE 2497 01:32:06,699 --> 01:32:08,168 EMOTIONAL WELL-BEING, WE SUGGEST 2498 01:32:08,168 --> 01:32:10,069 BOTH ANIMAL TO HUMAN TRANSLATION 2499 01:32:10,069 --> 01:32:12,572 OF NEUROMECHANISTIC INSIGHTS 2500 01:32:12,572 --> 01:32:14,774 TAKING ADVANTAGE OF THE TOOLS 2501 01:32:14,774 --> 01:32:17,510 AVAILABLE IN ANNUAL RESEARCH 2502 01:32:17,510 --> 01:32:19,612 PARTICULARLY THROUGH THE BRAIN 2503 01:32:19,612 --> 01:32:21,147 INITIATIVE EFFORTS, AS WELL AS 2504 01:32:21,147 --> 01:32:23,516 IN THE REVERSE DIRECTION, WE 2505 01:32:23,516 --> 01:32:25,685 EMPHASIZE HUMAN TO ANIMAL 2506 01:32:25,685 --> 01:32:28,254 TRANSLATION OF EWB FEATURES AND 2507 01:32:28,254 --> 01:32:31,691 HEALTH IMPACTS SO THAT CAN MATCH 2508 01:32:31,691 --> 01:32:35,261 SUBJECTIVE REPORT TO OBJECTIVE 2509 01:32:35,261 --> 01:32:40,600 MEASUREMENTS AND ENRICH 2510 01:32:40,600 --> 01:32:41,401 ENVIRONMENTAL DESIGN AND SOCIAL 2511 01:32:41,401 --> 01:32:44,103 EXPERIENCE FOR ANIMAL RESEARCH 2512 01:32:44,103 --> 01:32:45,405 AND MODEL AGING AND DISEASE 2513 01:32:45,405 --> 01:32:45,972 RELATED CHANGES. 2514 01:32:45,972 --> 01:32:47,740 SO THE CROSS-SPECIES STUDIES, 2515 01:32:47,740 --> 01:32:50,276 THERE'S A HUGE LITERATURE AND 2516 01:32:50,276 --> 01:32:54,714 THE DIALOGUE ACROSS DIFFERENT 2517 01:32:54,714 --> 01:32:55,582 DISCIPLINES IS A CHALLENGE, SO 2518 01:32:55,582 --> 01:32:56,916 WE'RE IN THE PROCESS DEVELOPING 2519 01:32:56,916 --> 01:33:00,720 A KNOWLEDGE DATABASE TO ALLOW 2520 01:33:00,720 --> 01:33:01,354 RESEARCHERS INTERESTED IN THIS 2521 01:33:01,354 --> 01:33:03,423 TOPIC TO SEARCH, EVALUATE AND 2522 01:33:03,423 --> 01:33:06,125 UPDATE RELEVANT CONTENT MESSAGE 2523 01:33:06,125 --> 01:33:08,795 AND THIS IS ONGOING AND 2524 01:33:08,795 --> 01:33:10,463 HOPEFULLY AN ITERATIVE PROCESS 2525 01:33:10,463 --> 01:33:12,899 TO ENGAGE MORE COMMUNITY. 2526 01:33:12,899 --> 01:33:16,169 SO FINALLY, WE HAD FUNDED A 2527 01:33:16,169 --> 01:33:18,705 SERIES OF PILOT PROJECTS 2528 01:33:18,705 --> 01:33:21,841 INCLUDING MATTERS OF EMOTIONAL 2529 01:33:21,841 --> 01:33:22,942 EXPERIENCE -- INNOVATIVE BRAIN 2530 01:33:22,942 --> 01:33:24,878 IMAGE AND DECODING METHODS 2531 01:33:24,878 --> 01:33:28,348 RELATED TO EWB AND CAUSAL 2532 01:33:28,348 --> 01:33:30,416 MECHANISM FOR EWB RELATED 2533 01:33:30,416 --> 01:33:31,084 BRAIN-BODY INTERACTIONS. 2534 01:33:31,084 --> 01:33:35,188 WE HAVE NINE PROJECTS SPREAD 2535 01:33:35,188 --> 01:33:37,257 ACROSS BOTH ANIMAL AND HUMAN 2536 01:33:37,257 --> 01:33:38,157 RESEARCH AND AT MULTIPLE 2537 01:33:38,157 --> 01:33:39,025 UNIVERSITIES. 2538 01:33:39,025 --> 01:33:42,328 SO FINALLY, IN SUMMARY, WE HAVE 2539 01:33:42,328 --> 01:33:43,997 DEVELOPED A CONCEPTUAL AND 2540 01:33:43,997 --> 01:33:47,000 OPERATIONAL FRAMEWORK FOR EWB 2541 01:33:47,000 --> 01:33:51,838 AND BRAIN AGING AND OUR NEW 2542 01:33:51,838 --> 01:33:53,840 DIRECTIONS INTERESTED IN 2543 01:33:53,840 --> 01:33:54,941 NEUROMODULATORY INTERVENTIONS 2544 01:33:54,941 --> 01:33:56,142 AND PLASTICITY ORIENTED 2545 01:33:56,142 --> 01:33:59,779 INTERVENTIONS TO PROMOTE EWB AND 2546 01:33:59,779 --> 01:34:01,981 HELP WITH OLDER ADULTS WITH 2547 01:34:01,981 --> 01:34:03,383 NEUROPSYCHIATRIC SYMPTOMS. 2548 01:34:03,383 --> 01:34:06,586 WITH THAT, I'LL THANK EVERYONE'S 2549 01:34:06,586 --> 01:34:06,853 ATTENTION. 2550 01:34:06,853 --> 01:34:07,120 THANK YOU. 2551 01:34:07,120 --> 01:34:17,297 [APPLAUSE] 2552 01:34:20,566 --> 01:34:21,634 >> GOOD MORNING. 2553 01:34:21,634 --> 01:34:22,802 I'M LISA PROSSER FROM UNIVERSITY 2554 01:34:22,802 --> 01:34:23,670 OF MICHIGAN AND I'M REALLY 2555 01:34:23,670 --> 01:34:24,904 DELIGHTED TO HAVE AN OPPORTUNITY 2556 01:34:24,904 --> 01:34:26,205 TO SHARE SOME OF THE WORK THAT'S 2557 01:34:26,205 --> 01:34:28,975 BEEN DEVELOPED AS PART OF THE 2558 01:34:28,975 --> 01:34:31,044 FAMILY WELL-BEING NETWORK OR 2559 01:34:31,044 --> 01:34:33,112 FAMNET IN PARTNERSHIP WITH 2560 01:34:33,112 --> 01:34:37,417 MYCO-PIs. 2561 01:34:37,417 --> 01:34:39,485 AS WELL AS IN CLOSE 2562 01:34:39,485 --> 01:34:42,221 COLLABORATION WITH TRACY KING, 2563 01:34:42,221 --> 01:34:44,590 PROGRAM OFFICER FROM NICHD, AS 2564 01:34:44,590 --> 01:34:46,092 WELL AS ERIN QUINLAN, SCIENTIFIC 2565 01:34:46,092 --> 01:34:50,897 OFFICER FROM NICCH. 2566 01:34:50,897 --> 01:34:52,332 THE OVERALL GOAL FOR OUR NETWORK 2567 01:34:52,332 --> 01:34:53,666 IS TO SUPPORT AND ADVANCE 2568 01:34:53,666 --> 01:34:55,168 RESEARCH ON THE MEASUREMENT OF 2569 01:34:55,168 --> 01:34:56,169 FAMILY WELL-BEING AND PEDIATRIC 2570 01:34:56,169 --> 01:34:59,005 QUALITY OF LIFE. 2571 01:34:59,005 --> 01:35:01,140 BY FUNDING NEW AREAS OF STUDY, 2572 01:35:01,140 --> 01:35:02,108 SUPPORTING AND MENTORING THE 2573 01:35:02,108 --> 01:35:03,209 NEXT GENERATION OF SCHOLARS AND 2574 01:35:03,209 --> 01:35:04,477 PROVIDING EDUCATION AND 2575 01:35:04,477 --> 01:35:08,247 RESOURCES FOR RESEARCHERS. 2576 01:35:08,247 --> 01:35:10,149 SO THIS SLIDE SHOWS OUR FUNDED 2577 01:35:10,149 --> 01:35:12,452 PILOT GRANTEES AND SCHOLAR CORE 2578 01:35:12,452 --> 01:35:12,752 MEMBERS. 2579 01:35:12,752 --> 01:35:16,489 SO WE FUNDED SO FAR 13 SCHOLARS 2580 01:35:16,489 --> 01:35:18,157 AROUND PILOT PROJECT AWARDEES 2581 01:35:18,157 --> 01:35:19,459 ACROSS THE COUNTRY THROUGH A 2582 01:35:19,459 --> 01:35:20,860 COMPETITIVE SELECTION PROCESS. 2583 01:35:20,860 --> 01:35:22,362 AND OF THESE, TWO HAVE RECEIVED 2584 01:35:22,362 --> 01:35:23,763 FUNDING BOTH AS A SCHOLAR AS 2585 01:35:23,763 --> 01:35:27,133 WELL AS FOR PILOT GRANTS. 2586 01:35:27,133 --> 01:35:29,235 THEY'RE ALL FOCUS THE ON FAMILY 2587 01:35:29,235 --> 01:35:30,803 WELL-BEING BUT ALSO ON PEDIATRIC 2588 01:35:30,803 --> 01:35:31,771 QUALITY OF LIFE WITH A VERY 2589 01:35:31,771 --> 01:35:33,406 DIVERSE SET OF TOPICS BEING 2590 01:35:33,406 --> 01:35:34,507 PURSUED AND I'LL SHARE JUST A 2591 01:35:34,507 --> 01:35:35,708 COUPLE OF EXAMPLES OF THE TITLES 2592 01:35:35,708 --> 01:35:37,477 OF THEIR STUDIES. 2593 01:35:37,477 --> 01:35:40,079 ONE IS FOCUSING ON PATIENT AND 2594 01:35:40,079 --> 01:35:40,947 CAREGIVER WELL-BEING IN 2595 01:35:40,947 --> 01:35:42,248 PEDIATRIC HEART FAILURE. 2596 01:35:42,248 --> 01:35:44,283 ANOTHER IS USING PROMIS MEASURES 2597 01:35:44,283 --> 01:35:48,521 TO CHARACTERIZE THE EMOTIONAL 2598 01:35:48,521 --> 01:35:53,993 WELL-BEING OF COMIRN WITH CHILDH 2599 01:35:53,993 --> 01:35:55,528 MEDICAL COMPLEXITY. 2600 01:35:55,528 --> 01:35:57,230 ANOTHER IS LOOKING AT 2601 01:35:57,230 --> 01:35:57,964 UNDERSTANDING WELL-BEING IN 2602 01:35:57,964 --> 01:36:00,033 FAMILIES WITH AN INDIVIDUAL WITH 2603 01:36:00,033 --> 01:36:00,566 INTELLECTUAL DISABILITY. 2604 01:36:00,566 --> 01:36:03,202 AND FINALLY JUST ANOTHER EXAMPLE 2605 01:36:03,202 --> 01:36:05,138 IS ONE THAT'S FOCUSING ON 2606 01:36:05,138 --> 01:36:07,140 IDENTIFYING YOUTH CAREGIVERS AND 2607 01:36:07,140 --> 01:36:09,208 UNDERSTANDING THEIR QUALITY OF 2608 01:36:09,208 --> 01:36:10,710 LIFE UTILIZING DATA FROM THE 2609 01:36:10,710 --> 01:36:11,244 V.A. POPULATION. 2610 01:36:11,244 --> 01:36:13,346 SO IT'S A HIGHLY 2611 01:36:13,346 --> 01:36:14,347 INTERDISCIPLINARY COHORT OF 2612 01:36:14,347 --> 01:36:15,982 SCHOLARS AND PILOT AWARDEES 2613 01:36:15,982 --> 01:36:17,884 COMING FROM VARIOUS DISCIPLINES 2614 01:36:17,884 --> 01:36:20,486 WITHIN MEDICINE, PSYCHIATRY, 2615 01:36:20,486 --> 01:36:23,022 PEDIATRICS, NURSING, SOCIOLOGY, 2616 01:36:23,022 --> 01:36:25,224 GENETICS, EPIDEMIOLOGY, SURGERY, 2617 01:36:25,224 --> 01:36:26,459 ETHICS, DECISION SCIENCES, 2618 01:36:26,459 --> 01:36:28,594 PUBLIC HEALTH AND MORE. 2619 01:36:28,594 --> 01:36:30,363 YOU CAN READ MORE ABOUT ALL OF 2620 01:36:30,363 --> 01:36:31,964 OUR AWARDEES AND THEIR PROJECTS 2621 01:36:31,964 --> 01:36:37,303 ON OUR WEBSITE. 2622 01:36:37,303 --> 01:36:39,505 JUST TO STEP BACK AND HIGHLIGHT 2623 01:36:39,505 --> 01:36:42,308 THE OVERALL PURPOSE OF OUR 2624 01:36:42,308 --> 01:36:43,476 SCHOLAR CORE AND PILOT PROJECTS 2625 01:36:43,476 --> 01:36:45,211 WAS TO SUPPORT AND FOSTER THE 2626 01:36:45,211 --> 01:36:46,512 SCHOLAR PIPELINE FOR FUTURE 2627 01:36:46,512 --> 01:36:48,381 RESEARCH ON FAMILY WELL-BEING 2628 01:36:48,381 --> 01:36:49,082 MEASUREMENT. 2629 01:36:49,082 --> 01:36:50,683 SO CONSISTENT WITH THESE 2630 01:36:50,683 --> 01:36:51,818 OBJECTIVES, THE FUNDING 2631 01:36:51,818 --> 01:36:53,586 OPPORTUNITIES WERE INTENDED FOR 2632 01:36:53,586 --> 01:36:55,421 TRAINEES AND FOR JUNIOR FACULTY 2633 01:36:55,421 --> 01:36:57,590 TO PROVIDE MULTIDISCIPLINARY 2634 01:36:57,590 --> 01:36:58,624 MENTORING AND TRAINING AND TO 2635 01:36:58,624 --> 01:37:00,193 CREATE A PEER NETWORK OF 2636 01:37:00,193 --> 01:37:03,129 LIKE-MINDED RESEARCHERS. 2637 01:37:03,129 --> 01:37:04,931 WE USE THE FAMNET WEBSITE AND 2638 01:37:04,931 --> 01:37:07,800 INFRASTRUCTURE TO PROMOTE THE 2639 01:37:07,800 --> 01:37:09,435 RESEARCH AND ON THE SLIDE I'VE 2640 01:37:09,435 --> 01:37:10,636 LISTED A FEW OF THE COMMON 2641 01:37:10,636 --> 01:37:13,372 THEMES INCLUDING THE USE OF 2642 01:37:13,372 --> 01:37:14,107 PROMISE MEASURES, THE 2643 01:37:14,107 --> 01:37:15,641 UTILIZATION OF SCOPING REVIEWS 2644 01:37:15,641 --> 01:37:17,176 IN MANY OF THESE STUDIES TO 2645 01:37:17,176 --> 01:37:19,445 IDENTIFY AREAS OF NEEDED 2646 01:37:19,445 --> 01:37:21,981 RESEARCH GIVEN THE STAGE OF THIS 2647 01:37:21,981 --> 01:37:22,348 FIELD. 2648 01:37:22,348 --> 01:37:23,983 PROJECTS THAT FOCUS ON EITHER 2649 01:37:23,983 --> 01:37:25,051 FAMILY WELL-BEING OR PEDIATRIC 2650 01:37:25,051 --> 01:37:28,221 QUALITY OF LIFE OR SEVERAL THAT 2651 01:37:28,221 --> 01:37:29,155 FEATURE BOTH. 2652 01:37:29,155 --> 01:37:30,456 DESCRIBING AND MEASURING THE 2653 01:37:30,456 --> 01:37:31,958 EXPERIENCE OF CAREGIVERS, 2654 01:37:31,958 --> 01:37:34,594 ESPECIALLY PARENT CAREGIVERS, AS 2655 01:37:34,594 --> 01:37:35,761 WELL AS THE LESS STUDIED BUT 2656 01:37:35,761 --> 01:37:38,264 IMPORTANT POPULATION OF YOUTH 2657 01:37:38,264 --> 01:37:38,698 CAREGIVERS. 2658 01:37:38,698 --> 01:37:40,333 THESE PROJECTS SPECIFICALLY 2659 01:37:40,333 --> 01:37:41,934 RELATE TO BOTH FAMILY WELL-BEING 2660 01:37:41,934 --> 01:37:43,870 AND PEDIATRIC QUALITY OF LIFE 2661 01:37:43,870 --> 01:37:44,737 REFLECTING THOSE DUAL AIMS OF 2662 01:37:44,737 --> 01:37:47,406 OUR NETWORK. 2663 01:37:47,406 --> 01:37:48,708 FINALLY MANY OF THESE FUNDED 2664 01:37:48,708 --> 01:37:50,176 STUDIES CAPTURE SITUATIONS THAT 2665 01:37:50,176 --> 01:37:52,879 INCLUDE CHILDREN WITH MEDICAL 2666 01:37:52,879 --> 01:37:57,250 COMPLEXITY. 2667 01:37:57,250 --> 01:37:58,618 AS THESE NEW INVESTIGATORS 2668 01:37:58,618 --> 01:38:00,486 ADVANCE THEIR RESEARCH BY ANNUAL 2669 01:38:00,486 --> 01:38:02,121 GRANTEE RETREATS PROVIDED 2670 01:38:02,121 --> 01:38:05,324 ESSENTIAL OPPORTUNITIES FOR 2671 01:38:05,324 --> 01:38:07,093 NETWORKING AND MENTORSHIP. 2672 01:38:07,093 --> 01:38:08,394 AND WHILE PART OF THE PROCESS 2673 01:38:08,394 --> 01:38:10,296 REQUIRED APPLICANTS TO IDENTIFY 2674 01:38:10,296 --> 01:38:11,831 THEIR OWN MENTORS, THEY COULD 2675 01:38:11,831 --> 01:38:12,932 ALSO REQUEST ADDITIONAL 2676 01:38:12,932 --> 01:38:14,367 MENTORSHIP THROUGH THE NETWORK 2677 01:38:14,367 --> 01:38:16,068 AND THROUGH THIS PROCESS WE 2678 01:38:16,068 --> 01:38:17,069 MATCHED FIVE EARLY YEAR 2679 01:38:17,069 --> 01:38:18,271 INVESTIGATORS WITH NEW MENTORS 2680 01:38:18,271 --> 01:38:19,839 FROM WITHIN THE NETWORK, 2681 01:38:19,839 --> 01:38:21,040 EXPANDING THEIR MEMBERSHIP TEAM 2682 01:38:21,040 --> 01:38:28,214 AND ALSO FACILITATING NETWORK. 2683 01:38:28,214 --> 01:38:30,383 WE DEVELOPED A DEDICATED WEBSITE 2684 01:38:30,383 --> 01:38:31,617 PROVIDING EDUCATION AND 2685 01:38:31,617 --> 01:38:33,853 RESOURCES FOR RESEARCH FOCUSED 2686 01:38:33,853 --> 01:38:35,054 ON FAMILY WELL-BEING AND ON 2687 01:38:35,054 --> 01:38:35,888 PEDIATRIC QUALITY OF LIFE. 2688 01:38:35,888 --> 01:38:37,890 AND THE WEBSITE PROVIDES 2689 01:38:37,890 --> 01:38:39,158 RELEVANT INFORMATION ON EVENTS 2690 01:38:39,158 --> 01:38:42,094 INCLUDING RECORDINGS OF O OUR 2691 01:38:42,094 --> 01:38:43,062 SEMINARS AS WELL AS NETWORK 2692 01:38:43,062 --> 01:38:44,230 ADJACENT MEETINGS AS WELL AS 2693 01:38:44,230 --> 01:38:44,997 INFORMATION AND RESOURCES FROM 2694 01:38:44,997 --> 01:38:47,300 THE PARTNER NETWORKS REPRESENTED 2695 01:38:47,300 --> 01:38:49,535 HERE FROM THE EMOTIONAL 2696 01:38:49,535 --> 01:38:55,208 WELL-BEING RFA. 2697 01:38:55,208 --> 01:38:57,610 A KEY FEATURE OF THE WEBSITE 2698 01:38:57,610 --> 01:38:59,145 INCLUDES THE DEVELOPMENT OF TWO 2699 01:38:59,145 --> 01:39:01,080 INSTRUMENT REPOSITORIES, THE 2700 01:39:01,080 --> 01:39:02,715 FAMILY WELL-BEING INSTRUMENT 2701 01:39:02,715 --> 01:39:04,617 REPOSITORY WHICH INCLUDES 23 2702 01:39:04,617 --> 01:39:05,918 INSTRUMENTS, AND THE PEDIATRIC 2703 01:39:05,918 --> 01:39:08,554 QUALITY OF LIFE INSTRUMENT 2704 01:39:08,554 --> 01:39:10,156 REPOSITORY, WHICH INCLUDES 45 2705 01:39:10,156 --> 01:39:11,190 INSTRUMENTS, RIGHT NOW IT'S 2706 01:39:11,190 --> 01:39:13,526 FOCUSED ON MEASURING -- 2707 01:39:13,526 --> 01:39:14,594 INCLUDING INSTRUMENTS THAT 2708 01:39:14,594 --> 01:39:15,528 MEASURE GENERIC QUALITY OF LIFE 2709 01:39:15,528 --> 01:39:18,064 AND WITH A FUTURE FOCUS TO 2710 01:39:18,064 --> 01:39:19,398 INCORPORATE CONDITION-SPECIFIC 2711 01:39:19,398 --> 01:39:20,466 INSTRUMENTS IN THE NEXT PHASE. 2712 01:39:20,466 --> 01:39:22,034 AND BOTH REPOSITORIES ARE 2713 01:39:22,034 --> 01:39:25,004 RESTRICTED TO INSTRUMENTS THAT 2714 01:39:25,004 --> 01:39:26,906 ARE PUBLICLY AVAILABLE TO MAKE 2715 01:39:26,906 --> 01:39:28,307 SURE THAT THESE ARE INSTRUMENTS 2716 01:39:28,307 --> 01:39:31,177 THAT CAN BE USED WIDELY BY 2717 01:39:31,177 --> 01:39:33,579 CURRENT AND FUTURE RESEARCHERS. 2718 01:39:33,579 --> 01:39:35,615 THEY'RE ANNOTATED AND TAGGED FOR 2719 01:39:35,615 --> 01:39:36,249 SEARCHING. 2720 01:39:36,249 --> 01:39:37,583 WE ALSO INCLUDE IN THE WEB SITE 2721 01:39:37,583 --> 01:39:39,452 LINKS TO THE OTHER EXISTING 2722 01:39:39,452 --> 01:39:40,886 ADULT WELL-BEING MEASURES 2723 01:39:40,886 --> 01:39:41,854 CATALOGS FROM THE OTHER EWB 2724 01:39:41,854 --> 01:39:47,193 NETWORKS. 2725 01:39:47,193 --> 01:39:49,195 THIS SLIDE SHOWS A SNAPSHOT. 2726 01:39:49,195 --> 01:39:49,695 OF 2727 01:39:49,695 --> 01:39:50,596 THE REPOSITORY INFORMATION 2728 01:39:50,596 --> 01:39:52,198 AVAILABLE FOR AN EXAMPLE 2729 01:39:52,198 --> 01:39:53,933 INSTRUMENT, THE BEACH CENTER 2730 01:39:53,933 --> 01:39:55,301 QUALITY OF LIFE INSTRUMENT. 2731 01:39:55,301 --> 01:39:57,103 FOR EACH INSTRUMENT THERE'S A 2732 01:39:57,103 --> 01:39:58,271 BRIEF HOLISTIC DESCRIPTION OF 2733 01:39:58,271 --> 01:40:00,539 THE MEASURE AS WELL AS A LIST OF 2734 01:40:00,539 --> 01:40:02,108 KEY REFERENCES. 2735 01:40:02,108 --> 01:40:03,542 DETAILED INFORMATION ON EACH 2736 01:40:03,542 --> 01:40:05,645 CONSTRUCT IS INCLUDED INCLUDING 2737 01:40:05,645 --> 01:40:07,947 CONSTRUCT, CONDITION, AGE, 2738 01:40:07,947 --> 01:40:09,048 COUNTRY WHERE DEVELOPED, NUMBER 2739 01:40:09,048 --> 01:40:10,816 OF ITEMS, SUBSCALES, 2740 01:40:10,816 --> 01:40:13,119 AVAILABILITY OF A SHORT FORM OF 2741 01:40:13,119 --> 01:40:16,155 IF IT'S AVAILABLE, RESPONDENT, 2742 01:40:16,155 --> 01:40:17,857 LANGUAGES, ALL THIS IS TAGGED 2743 01:40:17,857 --> 01:40:19,625 AND SEARCHABLE AND EASY TO 2744 01:40:19,625 --> 01:40:20,393 COMPARE ACROSS THE INSTRUMENTS 2745 01:40:20,393 --> 01:40:26,132 AS WELL. 2746 01:40:26,132 --> 01:40:27,633 IN JUNE WE ARE REALLY EXCITED TO 2747 01:40:27,633 --> 01:40:30,169 BE HOSTING A FAMILY WELL-BEING 2748 01:40:30,169 --> 01:40:31,203 SUMMIT WITH THE FOLLOWING KEY 2749 01:40:31,203 --> 01:40:33,606 OBJECTIVES. 2750 01:40:33,606 --> 01:40:35,007 FIRST, TO DEFINE THE FAMILY FROM 2751 01:40:35,007 --> 01:40:36,075 DIFFERENT PERSPECTIVES. 2752 01:40:36,075 --> 01:40:37,610 THERE ARE MANY, MANY POTENTIAL 2753 01:40:37,610 --> 01:40:39,378 DEAF ANYTHINGS FOR FAMILY. 2754 01:40:39,378 --> 01:40:40,680 CULTURAL, LEGAL, PRACTICAL, 2755 01:40:40,680 --> 01:40:42,348 INCLUDING WHO'S PROVIDING 2756 01:40:42,348 --> 01:40:43,516 CAREGIVING. 2757 01:40:43,516 --> 01:40:44,150 ARTICULATING THE POSSIBILITIES 2758 01:40:44,150 --> 01:40:46,252 AND THEIR RELEVANCE TO MEASURING 2759 01:40:46,252 --> 01:40:47,053 FAMILY WELL-BEING WILL BE 2760 01:40:47,053 --> 01:40:48,187 ESSENTIAL TO MOVING OUR FIELD 2761 01:40:48,187 --> 01:40:50,423 FORWARD. 2762 01:40:50,423 --> 01:40:51,857 SECOND, HOW TO DEFINE AND 2763 01:40:51,857 --> 01:40:53,159 MEASURE FAMILY OUTCOMES, SO 2764 01:40:53,159 --> 01:40:55,494 CONSIDERING THE FAMILY AS AN 2765 01:40:55,494 --> 01:40:57,830 ENTITY AND NOT AS THE SUM OF ITS 2766 01:40:57,830 --> 01:40:58,898 INDIVIDUAL MEMBERS, CONSIDERING 2767 01:40:58,898 --> 01:40:59,899 FRAME WORKS FROM OTHER FIELDS 2768 01:40:59,899 --> 01:41:02,301 SUCH AS ORGANIZATION STUDIES, 2769 01:41:02,301 --> 01:41:05,738 WHICH HAVE FOR QUITE SOME TIME 2770 01:41:05,738 --> 01:41:07,273 VALUED THE OUTCOMES OF A GROUP 2771 01:41:07,273 --> 01:41:08,674 DISTINCT FROM THAT OF THE 2772 01:41:08,674 --> 01:41:10,443 INDIVIDUALS WITHIN IT. 2773 01:41:10,443 --> 01:41:11,811 AND FINALLY, TO USE THE SUMMIT 2774 01:41:11,811 --> 01:41:13,446 AS AN OPPORTUNITY TO OUTLINE A 2775 01:41:13,446 --> 01:41:16,182 FUTURE RESEARCH AGENDA. 2776 01:41:16,182 --> 01:41:17,750 SO THIS WILL BE THE CULMINATING 2777 01:41:17,750 --> 01:41:19,485 EVENT FOR OUR GRANTEES AND THEIR 2778 01:41:19,485 --> 01:41:20,553 MENTORS, FOR OUR PARTNER 2779 01:41:20,553 --> 01:41:23,756 NETWORKS THAT WE'VE BEEN WORKING 2780 01:41:23,756 --> 01:41:25,358 WITH WHO WILL BE ENGAGED FOR 2781 01:41:25,358 --> 01:41:26,225 SELECT OUTSIDE EXPERTS AND WILL 2782 01:41:26,225 --> 01:41:28,127 ALSO INCLUDE THE PUBLICATION OF 2783 01:41:28,127 --> 01:41:31,197 THESE CONFERENCE PROCEEDINGS TO 2784 01:41:31,197 --> 01:41:32,465 SERVE TO DOCUMENT WHERE THE 2785 01:41:32,465 --> 01:41:33,866 FIELD IS AND POTENTIAL FUTURE 2786 01:41:33,866 --> 01:41:37,036 DIRECTIONS. 2787 01:41:37,036 --> 01:41:39,138 AS WE LOOK FORWARD, WE'RE REALLY 2788 01:41:39,138 --> 01:41:40,973 EXCITED TO CONTINUE ACTIVITY TO 2789 01:41:40,973 --> 01:41:42,641 SUPPORT THE SUCCESS OF OUR 2790 01:41:42,641 --> 01:41:45,077 SCHOLAR CORE AND PILOT PROJECT 2791 01:41:45,077 --> 01:41:46,579 AWARDEES, INCLUDING MENTORING, 2792 01:41:46,579 --> 01:41:47,380 NETWORKING, BUILDING 2793 01:41:47,380 --> 01:41:49,315 CONNECTIONS, AND OVERALL 2794 01:41:49,315 --> 01:41:50,616 SUPPORTING THE CAREER 2795 01:41:50,616 --> 01:41:52,051 TRAJECTORIES OF OUR JUNIOR 2796 01:41:52,051 --> 01:41:54,153 SCHOLARS. 2797 01:41:54,153 --> 01:41:55,388 WE'LL CONTINUE TO DEVELOP 2798 01:41:55,388 --> 01:41:58,357 RESOURCES TO SUPPORT RESEARCH IN 2799 01:41:58,357 --> 01:42:01,961 THIS AREA, INCLUDING THE STREAM 2800 01:42:01,961 --> 01:42:02,928 OF PUBLICATIONS FROM THE PILOT 2801 01:42:02,928 --> 01:42:03,996 PROJECTS. 2802 01:42:03,996 --> 01:42:05,498 WE'RE PLANNING A MANUSCRIPT 2803 01:42:05,498 --> 01:42:07,199 FOCUSED ON SUMMARIZING THE STATE 2804 01:42:07,199 --> 01:42:08,868 OF THE SCIENCE RELATING TO BEST 2805 01:42:08,868 --> 01:42:10,469 PRACTICES FOR USE AND PROXIES IN 2806 01:42:10,469 --> 01:42:11,237 MEASURING PEDIATRIC QUALITY OF 2807 01:42:11,237 --> 01:42:12,304 LIFE. 2808 01:42:12,304 --> 01:42:13,873 AND PROCEEDINGS FROM THE SUMMIT 2809 01:42:13,873 --> 01:42:14,774 TO CHARACTERIZE A FUTURE 2810 01:42:14,774 --> 01:42:15,875 RESEARCH AGENDA. 2811 01:42:15,875 --> 01:42:17,476 SO WE'LL CONTINUE TO SUPPLEMENT 2812 01:42:17,476 --> 01:42:19,245 THE REPOSITORIES ON FAMILY 2813 01:42:19,245 --> 01:42:20,246 WELL-BEING AND PEDIATRIC QUALITY 2814 01:42:20,246 --> 01:42:22,448 OF LIFE INSTRUMENTS, AND OVERALL 2815 01:42:22,448 --> 01:42:24,083 WE LOOK FORWARD TO CONTINUING TO 2816 01:42:24,083 --> 01:42:25,618 SUPPORT AND ADVANCE RESEARCH ON 2817 01:42:25,618 --> 01:42:26,685 THE MEASUREMENT OF FAMILY 2818 01:42:26,685 --> 01:42:27,987 WELL-BEING AND PEDIATRIC QUALITY 2819 01:42:27,987 --> 01:42:29,488 OF LIFE. 2820 01:42:29,488 --> 01:42:31,891 OUR NETWORK HAS GROWN FROM 2821 01:42:31,891 --> 01:42:33,959 6 MEMBERS TO 72 RESEARCHERS OVER 2822 01:42:33,959 --> 01:42:35,461 THE LAST THREE YEARS, AND WE 2823 01:42:35,461 --> 01:42:36,695 VERY MUCH LOOK FORWARD TO 2824 01:42:36,695 --> 01:42:37,930 CONTINUED GROWTH AND CONTINUED 2825 01:42:37,930 --> 01:42:38,297 COLLABORATIONS. 2826 01:42:38,297 --> 01:42:38,998 THANK YOU. 2827 01:42:38,998 --> 01:42:40,399 I'LL TURN IT BACK OVER. 2828 01:42:40,399 --> 01:42:50,576 [APPLAUSE] 2829 01:42:53,712 --> 01:42:55,114 >> WONDERFUL. 2830 01:42:55,114 --> 01:42:56,816 WELL, THANK YOU TO ALL OF YOU 2831 01:42:56,816 --> 01:42:58,651 WHO ARE HERE IN THE ROOM AND FOR 2832 01:42:58,651 --> 01:43:00,186 THE NETWORKS, AND EVERYONE WHO 2833 01:43:00,186 --> 01:43:02,421 COULDN'T BE HERE IN PERSON. 2834 01:43:02,421 --> 01:43:03,622 WE JUST ARE SO APPRECIATIVE OF 2835 01:43:03,622 --> 01:43:04,790 ALL THE EXCITING AND IMPORTANT 2836 01:43:04,790 --> 01:43:06,392 WORK AS ILLUSTRATED REALLY 2837 01:43:06,392 --> 01:43:09,628 BEAUTIFULLY IN THE LAST HOUR, TO 2838 01:43:09,628 --> 01:43:10,796 ADVANCE THE SCIENCE AND FIELD 2839 01:43:10,796 --> 01:43:13,833 AND NUMBER OF RESEARCHERS 2840 01:43:13,833 --> 01:43:14,433 RESEARCHING EMOTIONAL 2841 01:43:14,433 --> 01:43:14,733 WELL-BEING. 2842 01:43:14,733 --> 01:43:16,769 SO WE WILL NOW BEGIN THE Q & A 2843 01:43:16,769 --> 01:43:18,270 PORTION OF THIS MEETING. 2844 01:43:18,270 --> 01:43:20,172 WE'LL PRIORITIZE QUESTIONS 2845 01:43:20,172 --> 01:43:22,608 SUBMITTED BY OUR VIDEOCAST 2846 01:43:22,608 --> 01:43:24,310 AUDIENCE, AND THEN IF THERE'S 2847 01:43:24,310 --> 01:43:25,144 TIME, WE'RE A LITTLE BEHIND 2848 01:43:25,144 --> 01:43:26,412 SCHEDULE SO IF THERE'S TIME, 2849 01:43:26,412 --> 01:43:28,447 WE'LL ASK SOME QUESTIONS FROM 2850 01:43:28,447 --> 01:43:30,349 PEOPLE HERE IN THE ROOM. 2851 01:43:30,349 --> 01:43:31,750 SO MY COLLEAGUE IS GOING TO READ 2852 01:43:31,750 --> 01:43:34,053 OUT SOME OF THE QUESTIONS AND 2853 01:43:34,053 --> 01:43:36,956 I'LL HELP MAKE SURE THAT WE HAVE 2854 01:43:36,956 --> 01:43:38,123 PEOPLE RESPOND AND YOU CAN USE 2855 01:43:38,123 --> 01:43:40,292 THE MICROPHONES THAT ARE AT EACH 2856 01:43:40,292 --> 01:43:42,361 OF YOUR SEATS, PRESSING A BUTTON 2857 01:43:42,361 --> 01:43:47,466 TO RESPOND TO QUESTIONS. 2858 01:43:47,466 --> 01:43:49,768 >> CAN EVERYONE HEAR ME? 2859 01:43:49,768 --> 01:43:50,002 >> YES. 2860 01:43:50,002 --> 01:43:55,841 >> THIS FIRST QUESTION IS FOR 2861 01:43:55,841 --> 01:43:58,143 DR. LIZ NIELSON FOR THE NIA 2862 01:43:58,143 --> 01:43:59,812 PROGRAM STUFF IN THE ROOM. 2863 01:43:59,812 --> 01:44:01,814 HAS NIA ALSO SET ASIDE AN AREA 2864 01:44:01,814 --> 01:44:03,682 OF STUDY ON THE IMPACT OF 2865 01:44:03,682 --> 01:44:05,651 DIAGNOSIS ON EMOTIONAL HEALTH 2866 01:44:05,651 --> 01:44:07,019 AND OVERALL WELL-BEING? 2867 01:44:07,019 --> 01:44:08,721 AGING WITHOUT DIAGNOSIS OR 2868 01:44:08,721 --> 01:44:10,689 MEDICATION SURELY PROVIDES MORE 2869 01:44:10,689 --> 01:44:12,892 POSITIVE RESULTS THAN AGING WITH 2870 01:44:12,892 --> 01:44:13,993 SEVERE DIAGNOSIS, MEDICATIONS 2871 01:44:13,993 --> 01:44:16,028 AND FAMILY LOSSES. 2872 01:44:16,028 --> 01:44:19,431 HAS THIS BEEN RESEARCHED? 2873 01:44:19,431 --> 01:44:21,667 >> THIS IS LIZ NIELSON FROM NIA. 2874 01:44:21,667 --> 01:44:24,703 I CAN TAKE THAT QUESTION. 2875 01:44:24,703 --> 01:44:26,071 AND SORT OF ANSWER INDIRECTLY. 2876 01:44:26,071 --> 01:44:26,972 SO ONE AREA THAT WE'RE VERY 2877 01:44:26,972 --> 01:44:28,874 INTERESTED IN IS THE IMPACT OF A 2878 01:44:28,874 --> 01:44:29,842 DIAGNOSIS OF ALZHEIMER'S DISEASE 2879 01:44:29,842 --> 01:44:32,244 OR RELATED DEMENTIAS ON MULTIPLE 2880 01:44:32,244 --> 01:44:33,779 ASPECTS OF PEOPLE'S LIVES. 2881 01:44:33,779 --> 01:44:37,349 WE HELD A NATIONAL ACADEMY OF 2882 01:44:37,349 --> 01:44:39,151 SCIENCES WORKSHOP ON THAT TOPIC 2883 01:44:39,151 --> 01:44:40,719 A COUPLE OF YEARS AGO AND 2884 01:44:40,719 --> 01:44:42,054 EXPLORED THE IMPACT ON PEOPLE'S 2885 01:44:42,054 --> 01:44:45,958 SOCIAL RELATIONSHIPS, ON STIGMA, 2886 01:44:45,958 --> 01:44:47,693 ON DECISIONS ABOUT WORK, AND ON 2887 01:44:47,693 --> 01:44:48,761 A HOST OF OTHER THINGS RELATED 2888 01:44:48,761 --> 01:44:50,596 TO CHOICES THEY MIGHT MAKE FOR 2889 01:44:50,596 --> 01:44:53,332 MEDICAL CARE, AND WE SEE THAT AS 2890 01:44:53,332 --> 01:44:55,701 REALLY A GROWING AREA OF 2891 01:44:55,701 --> 01:44:57,369 INVESTIGATION, ESPECIALLY AS 2892 01:44:57,369 --> 01:44:59,538 EARLIER OPPORTUNITIES TO GET 2893 01:44:59,538 --> 01:45:04,076 SOME BLOOD-BASED BIOMARKER AS 2894 01:45:04,076 --> 01:45:05,377 YOUR DEMENTIA DIAGNOSIS COMES ON 2895 01:45:05,377 --> 01:45:06,679 BOARD AND DIGITAL TOOLS FOR 2896 01:45:06,679 --> 01:45:07,413 EARLY ASSESSMENT. 2897 01:45:07,413 --> 01:45:08,380 THESE ARE IMPORTANT TOOLS TO 2898 01:45:08,380 --> 01:45:10,282 HAVE FOR SORT OF STUDYING THE 2899 01:45:10,282 --> 01:45:13,152 BASIC WAYS IN WHICH THESE 2900 01:45:13,152 --> 01:45:16,221 DISEASES UNFOLD, BUT ALSO CREATE 2901 01:45:16,221 --> 01:45:17,856 NEW CHALLENGES FOR PEOPLE FACING 2902 01:45:17,856 --> 01:45:20,259 THOSE DIAGNOSES. 2903 01:45:20,259 --> 01:45:21,727 RELATEDLY, TO THE QUESTION NOT 2904 01:45:21,727 --> 01:45:26,799 TO THAT OTHER WORKSHOP, BUT 2905 01:45:26,799 --> 01:45:28,200 YEARS AGO WE HAD A COLLABORATIVE 2906 01:45:28,200 --> 01:45:30,469 WORKSHOP WITH OUR COLLEAGUES IN 2907 01:45:30,469 --> 01:45:33,205 GERIATRICS AND CLINICAL 2908 01:45:33,205 --> 01:45:34,840 GERONTOLOGY AROUND MEASURES OF 2909 01:45:34,840 --> 01:45:37,242 EMOTIONAL WELL-BEING IN 2910 01:45:37,242 --> 01:45:39,144 OBSERVATIONAL AND -- FROM A 2911 01:45:39,144 --> 01:45:40,212 GERIATRICS PERSPECTIVE, TRYING 2912 01:45:40,212 --> 01:45:41,347 TO BRING THE IMPORTANCE OF 2913 01:45:41,347 --> 01:45:42,581 INCORPORATING THESE MEASURES 2914 01:45:42,581 --> 01:45:45,618 INTO MORE CLINICAL RESEARCH ON 2915 01:45:45,618 --> 01:45:46,719 CONDITIONS OF AGING AND THERE 2916 01:45:46,719 --> 01:45:49,622 WAS A WIDE ACCEPTANCE AND 2917 01:45:49,622 --> 01:45:50,255 ENTHUSIASM ABOUT THE IMPORTANCE 2918 01:45:50,255 --> 01:45:53,292 OF CAPTURING THESE OTHER ASPECTS 2919 01:45:53,292 --> 01:45:55,094 OF PEOPLE'S HEALTH IN THE 2920 01:45:55,094 --> 01:45:56,261 CONTEXT OF ILLNESS, PARTICULARLY 2921 01:45:56,261 --> 01:45:58,197 IN THE FIELD OF GERIATRICS, 2922 01:45:58,197 --> 01:46:03,168 WHERE QUESTIONS LIKE PEOPLE 2923 01:46:03,168 --> 01:46:04,169 SETTING GOALS FOR CARE ARE 2924 01:46:04,169 --> 01:46:05,137 REALLY IMPORTANT AND 2925 01:46:05,137 --> 01:46:06,872 APPRECIATING THE VALUE OF SORT 2926 01:46:06,872 --> 01:46:08,941 OF MORE SUBJECTIVE GOALS VERSUS 2927 01:46:08,941 --> 01:46:10,309 OBJECTIVE PHYSICAL HEALTH GOALS 2928 01:46:10,309 --> 01:46:12,211 AS ONE IS NAVIGATING ILLNESS 2929 01:46:12,211 --> 01:46:12,978 TRAJECTORIES IN LATER LIFE. 2930 01:46:12,978 --> 01:46:14,380 THANK YOU FOR THE QUESTION. 2931 01:46:14,380 --> 01:46:15,681 >> THANK YOU. 2932 01:46:15,681 --> 01:46:18,617 NEXT QUESTION? 2933 01:46:18,617 --> 01:46:21,820 >> THIS NEXT QUESTION IS FOR DR. 2934 01:46:21,820 --> 01:46:24,256 IN 2012, THE ICMH HOSTED 2935 01:46:24,256 --> 01:46:25,991 CREATIVE ARTS THERAPISTS AND 2936 01:46:25,991 --> 01:46:28,160 REPORTED BIOLOGICAL EVIDENCE OF 2937 01:46:28,160 --> 01:46:29,828 STRESS REDUCTION FROM 2938 01:46:29,828 --> 01:46:30,829 CREDENTIALED ART, MUSIC AND 2939 01:46:30,829 --> 01:46:32,231 DANCE MOVEMENT INTERVENTIONS 2940 01:46:32,231 --> 01:46:33,632 BASED ON BROAD EXISTING 2941 01:46:33,632 --> 01:46:37,302 RESEARCH. 2942 01:46:37,302 --> 01:46:41,240 IN 2011, ADAM PEARLMAN DESCRIBED 2943 01:46:41,240 --> 01:46:42,941 THE CREATIVE ARTS THERAPIES AS 2944 01:46:42,941 --> 01:46:43,809 LOW HANGING FRUIT. 2945 01:46:43,809 --> 01:46:45,711 MY QUESTION IS, HOW DOES THE 2946 01:46:45,711 --> 01:46:47,079 NICCH WORK TO IMPLEMENT 2947 01:46:47,079 --> 01:46:48,180 SCIENTIFIC PRASK TISES IT 2948 01:46:48,180 --> 01:46:50,249 ACCEPTS SO CONSUMERS CAN ACCESS 2949 01:46:50,249 --> 01:46:51,684 PROVEN INTERVENTIONS NOW TO SAVE 2950 01:46:51,684 --> 01:46:58,657 AND IMPROVE LIVES? 2951 01:46:58,657 --> 01:47:01,326 >> WELL, WE ARE VERY INTERESTED 2952 01:47:01,326 --> 01:47:04,496 IN THE ARTS IN GENERAL. 2953 01:47:04,496 --> 01:47:06,131 ONE OF THE AREAS THAT WE FOCUSED 2954 01:47:06,131 --> 01:47:09,468 QUITE A BIT JUST RECENTLY HAS 2955 01:47:09,468 --> 01:47:10,169 BEEN MUSIC. 2956 01:47:10,169 --> 01:47:12,304 WE HAVE ALSO -- WE HAVE A BIG 2957 01:47:12,304 --> 01:47:15,007 INITIATIVE ON MUSIC AND HEALTH. 2958 01:47:15,007 --> 01:47:16,875 WE JUST RECENTLY HAD A REALLY 2959 01:47:16,875 --> 01:47:22,648 WONDERFUL WORKSHOP THAT REALLY 2960 01:47:22,648 --> 01:47:24,149 EXEMPLIFIED -- OH, IT'S NOT 2961 01:47:24,149 --> 01:47:24,783 WORKING? 2962 01:47:24,783 --> 01:47:26,685 IT WAS A FANTASTIC WORKSHOP THAT 2963 01:47:26,685 --> 01:47:30,255 WAS REALLY ILLUMINATING BECAUSE 2964 01:47:30,255 --> 01:47:33,325 NOT ONLY IT INCORPORATED 2965 01:47:33,325 --> 01:47:36,628 RESEARCHERS, MUSICIANS, BUT ALSO 2966 01:47:36,628 --> 01:47:40,065 PE FORMERS OF MUSIC TOGETHER IN 2967 01:47:40,065 --> 01:47:42,434 A WONDERFUL KIND OF 2968 01:47:42,434 --> 01:47:43,635 COLLABORATIVE LEARNING 2969 01:47:43,635 --> 01:47:44,002 ENVIRONMENT. 2970 01:47:44,002 --> 01:47:45,537 I DON'T SEE ANY REASON WHY THIS 2971 01:47:45,537 --> 01:47:47,940 COULD NOT BE DONE WITH OTHER 2972 01:47:47,940 --> 01:47:50,709 TYPES OF ARTS, VISUAL ARTS, FOR 2973 01:47:50,709 --> 01:47:51,910 EXAMPLE, SO YEAH, WE'RE VERY 2974 01:47:51,910 --> 01:47:53,112 INTERESTED IN THIS AREA, NO 2975 01:47:53,112 --> 01:47:55,414 QUESTION ABOUT IT. 2976 01:47:55,414 --> 01:47:58,150 WE CAN'T DO A SPECIFIC TARGETED 2977 01:47:58,150 --> 01:47:59,485 INITIATIVE FOR EVERYTHING, BUT 2978 01:47:59,485 --> 01:48:01,820 THIS IS DEFINITELY SOMETHING 2979 01:48:01,820 --> 01:48:02,955 THAT WE ARE INTERESTED IN. 2980 01:48:02,955 --> 01:48:05,290 >> THANK YOU, DR. LANGEVIN. 2981 01:48:05,290 --> 01:48:05,858 NEXT QUESTION? 2982 01:48:05,858 --> 01:48:09,628 >> NEXT QUESTION IS FOR 2983 01:48:09,628 --> 01:48:09,995 DR. DAVIDSON. 2984 01:48:09,995 --> 01:48:11,330 HOW ARE RESEARCH GROUPS THINKING 2985 01:48:11,330 --> 01:48:14,299 ABOUT RESPONSES EXPECTED BY 2986 01:48:14,299 --> 01:48:20,806 ACTIVE CONTROL PLA Z PLACEBO GR? 2987 01:48:20,806 --> 01:48:22,441 >> WELL, THANK YOU FOR THE 2988 01:48:22,441 --> 01:48:24,309 QUESTION. 2989 01:48:24,309 --> 01:48:27,012 WE HAVE LONG ADVOCATED THE 2990 01:48:27,012 --> 01:48:29,148 IMPORTANCE OF DEVELOPING 2991 01:48:29,148 --> 01:48:32,484 RIGOROUS CONTROL GROUPS FOR 2992 01:48:32,484 --> 01:48:35,954 MEDITATION AND RELATED KINDS OF 2993 01:48:35,954 --> 01:48:37,156 INTERVENTIONS. 2994 01:48:37,156 --> 01:48:40,826 THESE ARE INTERVENTIONS THAT ONE 2995 01:48:40,826 --> 01:48:43,195 CANNOT USE DOUBLE BLIND 2996 01:48:43,195 --> 01:48:46,231 PROCEDURES WITH BECAUSE YOU 2997 01:48:46,231 --> 01:48:48,801 REALLY CAN'T BLIND A PERSON FROM 2998 01:48:48,801 --> 01:48:51,003 RECEIVING A MEDITATION 2999 01:48:51,003 --> 01:48:51,470 INTERVENTION. 3000 01:48:51,470 --> 01:48:53,338 AND SO THEY REQUIRE THE 3001 01:48:53,338 --> 01:48:56,775 DEVELOPMENT OF OTHER MORE NOVEL 3002 01:48:56,775 --> 01:49:00,045 FORMS OF INTERVENTION. 3003 01:49:00,045 --> 01:49:06,118 AND AS THE VERY BRIEF DATA 3004 01:49:06,118 --> 01:49:07,219 GLIMPSE THAT I PRESENTED BUT 3005 01:49:07,219 --> 01:49:08,387 THERE'S ALSO LOTS OF OTHER DATA 3006 01:49:08,387 --> 01:49:12,157 IN THE LITERATURE SHOW, MANY OF 3007 01:49:12,157 --> 01:49:14,092 THESE, QUOTE, ACTIVE CONTROL 3008 01:49:14,092 --> 01:49:20,499 INTERVENTIONS ACTUALLY HAVE 3009 01:49:20,499 --> 01:49:24,403 USEFUL THERAPEUTIC BENEFIT. 3010 01:49:24,403 --> 01:49:27,105 AND SO I THINK THAT WE NEED TO 3011 01:49:27,105 --> 01:49:29,508 CONTINUE TO THINK CREATIVELY 3012 01:49:29,508 --> 01:49:32,978 ABOUT HOW TO DEPLOY THESE 3013 01:49:32,978 --> 01:49:37,783 INTERVENTIONS AND PARTICIPANTS 3014 01:49:37,783 --> 01:49:43,055 HAVE ACCEPTED THEM AND HAVE BEEN 3015 01:49:43,055 --> 01:49:44,189 VERY ENTHUSIASTIC ABOUT THEM, 3016 01:49:44,189 --> 01:49:49,094 AND SO IT HASN'T BEEN A PROBLEM 3017 01:49:49,094 --> 01:49:50,863 AT ALL IN DEPLOYING THEM. 3018 01:49:50,863 --> 01:49:53,332 THANK YOU FOR THE QUESTION. 3019 01:49:53,332 --> 01:49:54,566 >> THANK YOU, DR. DAVIDSON. 3020 01:49:54,566 --> 01:49:56,268 I THINK WE HAVE TIME FOR ONE 3021 01:49:56,268 --> 01:49:58,270 MORE QUESTION. 3022 01:49:58,270 --> 01:50:00,405 >> ALL RIGHT. 3023 01:50:00,405 --> 01:50:03,275 THIS QUESTION IS FOR DR. CONWELL 3024 01:50:03,275 --> 01:50:03,742 AND DR. WANG. 3025 01:50:03,742 --> 01:50:06,211 HAVE YOU STUDIED THE IMPACT OF 3026 01:50:06,211 --> 01:50:08,313 POLYPHARMACY IN BRAIN AGING AND 3027 01:50:08,313 --> 01:50:08,747 WELL-BEING? 3028 01:50:08,747 --> 01:50:10,349 IN PARTICULAR, THE SEVERE DAMAGE 3029 01:50:10,349 --> 01:50:11,750 INDUCED BY THE SIDE EFFECT OF 3030 01:50:11,750 --> 01:50:16,488 STATINS. 3031 01:50:16,488 --> 01:50:19,091 >> THIS IS DR. CONWELL. 3032 01:50:19,091 --> 01:50:21,093 I'LL TRY TO TAKE THAT ON. 3033 01:50:21,093 --> 01:50:23,028 THAT FALLS SOMEWHAT SQUARELY IN 3034 01:50:23,028 --> 01:50:25,130 THE MIDDLE OF OUR INTERESTS IN 3035 01:50:25,130 --> 01:50:27,165 THE RELATIONSHIP BETWEEN 3036 01:50:27,165 --> 01:50:30,569 GERIATRIC CONDITIONS OVERALL AND 3037 01:50:30,569 --> 01:50:31,770 EMOTIONAL WELL-BEING IN LATER 3038 01:50:31,770 --> 01:50:33,405 LIFE BECAUSE AS IS IMPLIED IN 3039 01:50:33,405 --> 01:50:38,810 YOUR QUESTION, POLYPHARMACY IS 3040 01:50:38,810 --> 01:50:40,445 RAMPANT IN OLDER ADULTS AND 3041 01:50:40,445 --> 01:50:43,815 ASSOCIATED WITH A WIDE RANGE OF 3042 01:50:43,815 --> 01:50:47,953 ADVERSE OUTCOMES. 3043 01:50:47,953 --> 01:50:49,221 HOW THEN TO TRANSLATE THAT INTO 3044 01:50:49,221 --> 01:50:50,355 THE STUDY OF EMOTIONAL 3045 01:50:50,355 --> 01:50:51,256 WELL-BEING IS A CHALLENGE WE'VE 3046 01:50:51,256 --> 01:50:52,457 NOT TAKEN ON YET. 3047 01:50:52,457 --> 01:50:54,026 WE HAVE A NUMBER OF STUDIES 3048 01:50:54,026 --> 01:50:55,560 GOING ON NOT WITHIN NEW BRAIN 3049 01:50:55,560 --> 01:50:59,898 AGING PER SE, BUT WITH RELATED 3050 01:50:59,898 --> 01:51:03,302 COLLEAGUES ON THE ISSUE OF 3051 01:51:03,302 --> 01:51:04,236 DEPRESCRIBING AS AN INTERVENTION 3052 01:51:04,236 --> 01:51:07,773 AND HOW TO MOST EFFECTIVELY 3053 01:51:07,773 --> 01:51:09,608 MANAGE THAT AND THEN AS A 3054 01:51:09,608 --> 01:51:10,642 COROLLARY, LOOKING TO SEE HOW 3055 01:51:10,642 --> 01:51:12,110 THAT IMPACTS EMOTIONAL 3056 01:51:12,110 --> 01:51:13,612 WELL-BEING PER SE. 3057 01:51:13,612 --> 01:51:15,380 BUT THE PARTICULAR THRUST OF 3058 01:51:15,380 --> 01:51:16,715 YOUR QUESTION FALLS A LITTLE BIT 3059 01:51:16,715 --> 01:51:20,652 OUTSIDE OF WHAT THE FOCUS OF OUR 3060 01:51:20,652 --> 01:51:21,920 CENTER NEW BRAIN AGE SOMETHING 3061 01:51:21,920 --> 01:51:25,891 PER SE. 3062 01:51:25,891 --> 01:51:27,626 AGING IS PER 3063 01:51:27,626 --> 01:51:27,793 SE. 3064 01:51:27,793 --> 01:51:31,596 >> I'D JUST ADD IN ONE COMMENT. 3065 01:51:31,596 --> 01:51:34,633 WE ARE ACTUALLY ALSO FUNDING A 3066 01:51:34,633 --> 01:51:37,803 PILOT ON ANIMAL STUDIES LOOKING 3067 01:51:37,803 --> 01:51:41,073 AT AUTONOMIC NERVOUS SYSTEM 3068 01:51:41,073 --> 01:51:44,409 CHANGES AND DRUGS IN AGING, SO I 3069 01:51:44,409 --> 01:51:47,012 THINK AT A DEEP MESS NICK TICK 3070 01:51:47,012 --> 01:51:48,113 LEVEL THERE'S SOME CONNECTION 3071 01:51:48,113 --> 01:51:50,282 BUT WE HAVEN'T REALLY MAPPED TO 3072 01:51:50,282 --> 01:51:50,816 EMOTIONAL WELL-BEING YET. 3073 01:51:50,816 --> 01:51:52,751 >> THANK YOU EVERYONE FOR 3074 01:51:52,751 --> 01:51:54,252 SUBMITTING QUESTIONS BY NIH 3075 01:51:54,252 --> 01:51:54,853 VIDEOCAST. 3076 01:51:54,853 --> 01:51:56,021 APOLOGIES WE CANNOT GET TO ALL 3077 01:51:56,021 --> 01:51:57,189 OF THEM, BUT WE HAVE THEM 3078 01:51:57,189 --> 01:51:58,857 RECORDED AND WILL CERTAINLY PASS 3079 01:51:58,857 --> 01:51:59,624 THEM ALONG TO THE APPROPRIATE 3080 01:51:59,624 --> 01:51:59,992 PARTIES. 3081 01:51:59,992 --> 01:52:01,793 SO WITH ENDING THAT SHOWCASE 3082 01:52:01,793 --> 01:52:03,628 SESSION, I WOULD NOW LIKE TO 3083 01:52:03,628 --> 01:52:05,130 SWITCH OVER TO INTRODUCE 3084 01:52:05,130 --> 01:52:06,298 DR. ERIC GARLAND, WHO WILL BE 3085 01:52:06,298 --> 01:52:07,966 GIVING OUR KEYNOTE ADDRESS. 3086 01:52:07,966 --> 01:52:08,934 DR. ERIC GARLAND IS 3087 01:52:08,934 --> 01:52:11,303 DISTINGUISHED ENDOWED CHAIR IN 3088 01:52:11,303 --> 01:52:11,803 RESEARCH, DISTINGUISHED 3089 01:52:11,803 --> 01:52:13,205 PROFESSOR AND ASSOCIATE DEAN FOR 3090 01:52:13,205 --> 01:52:14,573 RESEARCH IN THE UNIVERSITY OF 3091 01:52:14,573 --> 01:52:16,475 UTAH COLLEGE OF SOCIAL WORK. 3092 01:52:16,475 --> 01:52:18,343 DIRECTOR OF THE CENTER ON 3093 01:52:18,343 --> 01:52:20,379 MINDFULNESS AND INTEGRATIVE 3094 01:52:20,379 --> 01:52:21,747 HEALTH INTERVENTION DEVELOPMENT 3095 01:52:21,747 --> 01:52:24,783 AND ASSOCIATE DIRECTOR OF 3096 01:52:24,783 --> 01:52:25,350 INTEGRATIVE MEDICINE AT THE 3097 01:52:25,350 --> 01:52:27,019 HUNTS MAN CANCER INSTITUTE. 3098 01:52:27,019 --> 01:52:27,819 DR. GARLAND IS THE DEVELOPER OF 3099 01:52:27,819 --> 01:52:34,059 AN I FOCUS OND INSIGHTS DERIVEDM 3100 01:52:34,059 --> 01:52:36,228 COGNITIVE, AFFECTIVE AND 3101 01:52:36,228 --> 01:52:40,198 NEUROLOGICAL SCIENCE CALLED WHIE 3102 01:52:40,198 --> 01:52:42,167 WILL TELL US MORE ABOUT IN HIS 3103 01:52:42,167 --> 01:52:42,667 KEYNOTE PRESENTATION. 3104 01:52:42,667 --> 01:52:43,635 PLEASE SUBMIT YOUR QUESTIONS 3105 01:52:43,635 --> 01:52:45,170 THROUGH THE NIH VIDEOCAST FORM 3106 01:52:45,170 --> 01:52:46,471 AS HIS KEYNOTE WILL BE FOLLOWED 3107 01:52:46,471 --> 01:52:47,205 BY A BRIEF Q & A. 3108 01:52:47,205 --> 01:52:57,649 SO WITH THAT, DR. GARLAND. 3109 01:53:40,325 --> 01:53:41,560 >> WHILE THIS IS GOING I JUST 3110 01:53:41,560 --> 01:53:43,095 WANTED TO EXPRESS MY GRATITUDE. 3111 01:53:43,095 --> 01:53:45,163 IT'S REALLY AN HONOR TO BE HERE 3112 01:53:45,163 --> 01:53:47,466 AND PRESENT MY WORK AT NIH TO 3113 01:53:47,466 --> 01:53:50,068 THIS GROUP OF ESTEEMED 3114 01:53:50,068 --> 01:53:52,003 SCIENTIFIC LUMINARIES. 3115 01:53:52,003 --> 01:53:55,941 SO TODAY I'LL BE PRESENTING MY 3116 01:53:55,941 --> 01:54:01,880 WORK ON THE MECHANISMS BY 3117 01:54:01,880 --> 01:54:06,485 WHICH -- IMPROVES EMOTIONAL 3118 01:54:06,485 --> 01:54:07,185 WELL-BEING IN PEOPLE WITH 3119 01:54:07,185 --> 01:54:08,386 CHRONIC PAIN AND OPIOID MISUSE. 3120 01:54:08,386 --> 01:54:12,290 THANK YOU. 3121 01:54:12,290 --> 01:54:15,193 AND CLEARLY EMOTIONAL WELL-BEING 3122 01:54:15,193 --> 01:54:17,963 INTERVENTIONS HAVE APPLICATIONS 3123 01:54:17,963 --> 01:54:20,499 BEYOND THE TREATMENT OF CHRONIC 3124 01:54:20,499 --> 01:54:21,867 PAIN AND ADDICTION. 3125 01:54:21,867 --> 01:54:24,503 BUT THE CURRENT OPIOID CRISIS, 3126 01:54:24,503 --> 01:54:26,138 WHICH REPRESENTS A PERNICIOUS 3127 01:54:26,138 --> 01:54:28,440 THREAT TO PUBLIC HEALTH, MAY BE 3128 01:54:28,440 --> 01:54:30,342 ESPECIALLY TRACTABLE TO 3129 01:54:30,342 --> 01:54:30,976 EMOTIONAL WELL-BEING 3130 01:54:30,976 --> 01:54:31,977 INTERVENTIONS. 3131 01:54:31,977 --> 01:54:32,844 AND SO, THEREFORE, I THINK THIS 3132 01:54:32,844 --> 01:54:34,479 LINE OF WORK REPRESENTS AN 3133 01:54:34,479 --> 01:54:36,148 IMPORTANT USE CASE TO ILLUSTRATE 3134 01:54:36,148 --> 01:54:38,049 HOW THE SCIENCE OF EMOTIONAL 3135 01:54:38,049 --> 01:54:39,684 WELL-BEING CAN BE APPLIED MORE 3136 01:54:39,684 --> 01:54:41,319 BROADLY TO ADDRESS A WIDE RANGE 3137 01:54:41,319 --> 01:54:46,324 OF HEALTH CONDITIONS. 3138 01:54:46,324 --> 01:54:55,734 SO TO BEGIN N201 IN 2015 -- TO H 3139 01:54:55,734 --> 01:54:56,902 THEY ATTRIBUTED TO LARGE PART TO 3140 01:54:56,902 --> 01:54:58,303 THE OPIOID CRISIS. 3141 01:54:58,303 --> 01:55:00,105 A CRISIS THAT HAS BEEN TERMED A 3142 01:55:00,105 --> 01:55:02,040 DISEASE OF DESPAIR IN THE 3143 01:55:02,040 --> 01:55:03,375 EPIDEMIOLOGICAL LITERATURE. 3144 01:55:03,375 --> 01:55:05,076 AND THE DISEASE OF DESPAIR HAS 3145 01:55:05,076 --> 01:55:08,513 MANY SOURCES, FROM THE -- I'M 3146 01:55:08,513 --> 01:55:10,615 NOT TOUCHING ANYTHING HERE. 3147 01:55:10,615 --> 01:55:15,820 IS THIS ADVANCING AUTOMATICALLY? 3148 01:55:15,820 --> 01:55:17,622 THE DISEASE OF DESPAIR HAS MANY 3149 01:55:17,622 --> 01:55:24,029 SOURCES. 3150 01:55:24,029 --> 01:55:25,564 I THINK IT MIGHT BE ADVANCING 3151 01:55:25,564 --> 01:55:35,807 AUTOMATICALLY. 3152 01:55:44,916 --> 01:55:46,618 SO THE DISEASE OF DESPAIR HAS 3153 01:55:46,618 --> 01:55:47,619 MANY SOURCES FROM THE RISING 3154 01:55:47,619 --> 01:55:49,354 TIDE OF INCOME INEQUALITY TO THE 3155 01:55:49,354 --> 01:55:52,023 LACK OF OPPORTUNITY, TO 3156 01:55:52,023 --> 01:55:53,091 INTERGENERATIONAL VIOLENCE AND 3157 01:55:53,091 --> 01:55:56,027 TRAUMA, AND THE EGOCENTRIC 3158 01:55:56,027 --> 01:55:56,928 MATERIALISM, SOCIAL ISOLATION 3159 01:55:56,928 --> 01:55:58,096 AND DIGITAL ADDICTION THAT'S 3160 01:55:58,096 --> 01:56:00,899 SUCH A PART OF MODERN CULTURE. 3161 01:56:00,899 --> 01:56:01,900 TO SELF-MEDICATE AGAINST THESE 3162 01:56:01,900 --> 01:56:04,302 FORMS OF DESPAIR, WE SEEK EVER 3163 01:56:04,302 --> 01:56:05,003 MORE INTENSE FORMS OF 3164 01:56:05,003 --> 01:56:05,403 STIMULATION. 3165 01:56:05,403 --> 01:56:07,439 WE WANT FANCIER CARS, MORE 3166 01:56:07,439 --> 01:56:08,540 ELABORATE VACATIONS, MORE LIKES 3167 01:56:08,540 --> 01:56:10,208 ON SOCIAL MEDIA, BUT NOTHING 3168 01:56:10,208 --> 01:56:12,010 SEEMS TO FILL THE HOLE. 3169 01:56:12,010 --> 01:56:14,746 IN THE FACE OF THIS VACUUM OF 3170 01:56:14,746 --> 01:56:15,914 MEANING, IT WAS PERHAPS 3171 01:56:15,914 --> 01:56:16,781 INEVITABLE THAT LIFE WOULD 3172 01:56:16,781 --> 01:56:17,916 BECOME MORE PAINFUL AND INDEED 3173 01:56:17,916 --> 01:56:19,818 IT DID, RATES OF CHRONIC PAIN 3174 01:56:19,818 --> 01:56:22,587 SOARED IN THE U.S., FOR AN 3175 01:56:22,587 --> 01:56:23,888 ESTIMATED 50 MILLION AMERICANS 3176 01:56:23,888 --> 01:56:25,490 EXPERIENCE PAIN EACH YEAR AND TO 3177 01:56:25,490 --> 01:56:27,592 ALLEVIATE THIS EPIDEMIC OF PAIN, 3178 01:56:27,592 --> 01:56:28,994 OPIOID PRESCRIPTIONS CLIMBED. 3179 01:56:28,994 --> 01:56:31,396 IN 2015, 38% OF U.S. AMERICAN 3180 01:56:31,396 --> 01:56:35,166 ADULTS USED AN OPIOID THAT YEAR. 3181 01:56:35,166 --> 01:56:36,668 THIS DRAMATIC INCREASE IN OPIOID 3182 01:56:36,668 --> 01:56:38,703 USE HAS DRIVEN THE OPIOID CRISIS 3183 01:56:38,703 --> 01:56:40,639 WHICH HAS COST THIS COUNTRY 3184 01:56:40,639 --> 01:56:43,208 COUNTLESS LIVES UP TO TODAY. 3185 01:56:43,208 --> 01:56:45,043 I WANT TO BEGIN THIS TALK ON A 3186 01:56:45,043 --> 01:56:47,545 MORE HOPEFUL NOTE. 3187 01:56:47,545 --> 01:56:48,680 A PATIENT CAME TO SEE ME FOR 3188 01:56:48,680 --> 01:56:51,016 HELP WITH CHRONIC PAIN AND 3189 01:56:51,016 --> 01:56:51,549 OPIOID RELATED PROBLEMS. 3190 01:56:51,549 --> 01:56:53,218 HE RECEIVED A SERIES OF FIVE 3191 01:56:53,218 --> 01:56:55,186 FAILED BACK SURGERIES, AFTER 3192 01:56:55,186 --> 01:56:57,822 EACH ONE HAD BEEN PRESCRIBED 3193 01:56:57,822 --> 01:56:58,857 ESCALATING DOSES OF OPIOIDS. 3194 01:56:58,857 --> 01:57:04,729 HE AS HE STATED TO ME, I JUST DT 3195 01:57:04,729 --> 01:57:06,298 WANT TO BE IN PAIN. 3196 01:57:06,298 --> 01:57:07,832 I ASKED HIM TO TELL ME ABOUT A 3197 01:57:07,832 --> 01:57:09,167 TIME WHEN HE WASN'T IN SO MUCH 3198 01:57:09,167 --> 01:57:10,969 PAIN, AND HE TOLD ME THAT ON THE 3199 01:57:10,969 --> 01:57:13,371 WEEKENDS WHEN HIS GRANDKIDS CAME 3200 01:57:13,371 --> 01:57:15,006 OUT, HE WATCHED THEM PLAY IN THE 3201 01:57:15,006 --> 01:57:17,709 BACKYARD, HE BECAME SO FOCUSED 3202 01:57:17,709 --> 01:57:19,110 AND SO ABSORBED IN WATCHING THEM 3203 01:57:19,110 --> 01:57:21,646 PLAY THAT IT BROUGHT JOY TO HIS 3204 01:57:21,646 --> 01:57:23,148 HEART AND IN THAT MOMENT, HE 3205 01:57:23,148 --> 01:57:24,983 DIDN'T NOTICE HIS PAIN. 3206 01:57:24,983 --> 01:57:26,184 HIS PAIN WAS TEMPORARILY GONE. 3207 01:57:26,184 --> 01:57:30,422 SO WAS HIS DESIRE FOR OPIOIDS. 3208 01:57:30,422 --> 01:57:32,123 THIS CLINICAL ANECDOTE HINTS AT 3209 01:57:32,123 --> 01:57:34,092 A POTENTIAL UNTAPPED THERAPEUTIC 3210 01:57:34,092 --> 01:57:34,726 MECHANISM THAT COULD BE 3211 01:57:34,726 --> 01:57:36,294 LEVERAGED TO HELP ADDRESS THE 3212 01:57:36,294 --> 01:57:38,997 OPIOID CRISIS. 3213 01:57:38,997 --> 01:57:39,731 TO UNDERSTAND THIS CLAIM, WE 3214 01:57:39,731 --> 01:57:41,333 NEED TO UNDERSTAND HOW ADDICTION 3215 01:57:41,333 --> 01:57:43,735 IMPAIRS THE REGULATION OF PAIN 3216 01:57:43,735 --> 01:57:44,703 AND PLEASURE ON THE BRAIN. 3217 01:57:44,703 --> 01:57:46,705 ALSO KNOWN AS HEDONIC 3218 01:57:46,705 --> 01:57:47,772 DYSREGULATION IN THE SCIENTIFIC 3219 01:57:47,772 --> 01:57:50,275 LITERATURE. 3220 01:57:50,275 --> 01:57:51,476 TRADITIONALLY IN WESTERN 3221 01:57:51,476 --> 01:57:52,310 PHILOSOPHY, PLEASURE AND PAIN 3222 01:57:52,310 --> 01:57:54,145 ARE CONSIDERED OPPOSITES ON A 3223 01:57:54,145 --> 01:57:54,546 HEDONIC BALANCE. 3224 01:57:54,546 --> 01:57:56,448 SUCH THAT INCREASING EXPERIENCES 3225 01:57:56,448 --> 01:57:58,149 OF PAIN ARE THOUGHT TO OUTWEIGH 3226 01:57:58,149 --> 01:57:59,718 THE EXPERIENCE OF PLEASURE IN 3227 01:57:59,718 --> 01:58:03,688 EVERYDAY LIFE. 3228 01:58:03,688 --> 01:58:05,890 MODERN BIOLOGY SUGGESTS THAT 3229 01:58:05,890 --> 01:58:06,591 PLEASURE AND PAIN OPERATE 3230 01:58:06,591 --> 01:58:08,693 THROUGH A COMMON EMOTIONAL 3231 01:58:08,693 --> 01:58:11,563 CURRENCY IN THE BRAIN MEDIATED 3232 01:58:11,563 --> 01:58:13,264 BY THE DOPAMINE SYSTEM AND THE 3233 01:58:13,264 --> 01:58:14,599 ENDOGENOUS OPIOID SYSTEM AND 3234 01:58:14,599 --> 01:58:16,568 THESE SAME BRAIN SYSTEMS BECOME 3235 01:58:16,568 --> 01:58:18,336 HIJACKED BY ADDICTIVE DRUGS 3236 01:58:18,336 --> 01:58:19,971 THROUGH AN ALLOSTATIC PROCESS IN 3237 01:58:19,971 --> 01:58:22,607 WHICH CHRONIC EXPOSURE TO 3238 01:58:22,607 --> 01:58:24,642 OPIOIDS CAUSES NEUROPLASTIC 3239 01:58:24,642 --> 01:58:27,879 CHANGES TO CORTICAL LIMBIC 3240 01:58:27,879 --> 01:58:29,247 CIRCUITRY THAT INCREASE 3241 01:58:29,247 --> 01:58:30,915 SENSITIVITY TO PAIN, STRESS AND 3242 01:58:30,915 --> 01:58:34,085 DRUG-RELATED CUES WHILE 3243 01:58:34,085 --> 01:58:36,221 DECREASING SENSITIVITY TO THE 3244 01:58:36,221 --> 01:58:37,422 NATURAL HEALTHY PLEASURE AND 3245 01:58:37,422 --> 01:58:38,757 MEANING DRIVE FROM OBJECTS AND 3246 01:58:38,757 --> 01:58:39,357 EVENTS IN THE SOCIAL 3247 01:58:39,357 --> 01:58:42,460 ENVIRONMENT. 3248 01:58:42,460 --> 01:58:45,196 SO IN MY LABORATORY WE MEASURE 3249 01:58:45,196 --> 01:58:46,865 HEDONIC DYSREGULATION WITH THE 3250 01:58:46,865 --> 01:58:50,101 EMOTION REGULATION TASK. 3251 01:58:50,101 --> 01:58:51,236 PRESENTING WITH EMOTIONAL 3252 01:58:51,236 --> 01:58:51,903 IMAGES. 3253 01:58:51,903 --> 01:58:53,671 IN RESPONSE TO NEGATIVE IMAGES 3254 01:58:53,671 --> 01:58:54,739 PARTICIPANTS ARE ASKED TO EITHER 3255 01:58:54,739 --> 01:58:57,175 VIEW THE IMAGE OR REAPPRAISE THE 3256 01:58:57,175 --> 01:58:58,343 IMAGE BY REFRAMING THE MEANING 3257 01:58:58,343 --> 01:58:59,477 OF THE CONTENT OF THE IMAGE IN 3258 01:58:59,477 --> 01:59:03,882 SUCH A WAY AS TO SEE THAT IMAGE 3259 01:59:03,882 --> 01:59:06,017 DEPICTING AN OPPORTUNITY FOR 3260 01:59:06,017 --> 01:59:09,521 POTENTIAL GROWTH, PSYCHOLOGICAL 3261 01:59:09,521 --> 01:59:11,356 GROWTH OR MEANING IN THE FACE OF 3262 01:59:11,356 --> 01:59:13,892 ADVERSITY. 3263 01:59:13,892 --> 01:59:15,160 IN RESPONSE TO POSITIVE 3264 01:59:15,160 --> 01:59:16,060 EMOTIONAL STIMULI LIKE THIS 3265 01:59:16,060 --> 01:59:17,362 IMAGE OF THIS FATHER AND SON 3266 01:59:17,362 --> 01:59:19,464 ENJOYING THE DAY AT THE BEACH, 3267 01:59:19,464 --> 01:59:20,265 PARTICIPANTS ARE ASKED TO EITHER 3268 01:59:20,265 --> 01:59:22,367 VIEW THE IMAGE OR TO SAVOR THE 3269 01:59:22,367 --> 01:59:23,835 IMAGE BY MINDFULLY FOCUSING 3270 01:59:23,835 --> 01:59:25,170 THEIR ATTENTION ON WHAT IS 3271 01:59:25,170 --> 01:59:26,070 PLEASANT, BEAUTIFUL AND GOOD IN 3272 01:59:26,070 --> 01:59:31,376 THE IMAGE, AND APPRECIATING AND 3273 01:59:31,376 --> 01:59:33,711 AMPLIFYING ANY EMOTIONS OR 3274 01:59:33,711 --> 01:59:34,879 PLEASURABLE BODY EMOTIONS RISING 3275 01:59:34,879 --> 01:59:36,147 DURING THIS TASK. 3276 01:59:36,147 --> 01:59:37,849 VARIATIONS OF THIS EMOTIONAL 3277 01:59:37,849 --> 01:59:39,951 REGULATION TASK HAVE BEEN USED 3278 01:59:39,951 --> 01:59:41,619 FOR NEARLY THREE DECADES LED BY 3279 01:59:41,619 --> 01:59:43,054 PIE 'NOTHERRING WORK DONE BY 3280 01:59:43,054 --> 01:59:46,257 JAMES GROSS AND RICHIE DAVIDSON 3281 01:59:46,257 --> 01:59:48,092 RIGHT HERE IN THIS ROOM, ONE OF 3282 01:59:48,092 --> 01:59:49,260 MY PERSONAL SCIENTIFIC HEROS. 3283 01:59:49,260 --> 01:59:50,595 SO A NUMBER OF YEARS AGO, MY 3284 01:59:50,595 --> 01:59:53,398 COLLEAGUES AND I FOUND THAT 3285 01:59:53,398 --> 01:59:54,599 RELATIVE TO PATIENTS WHO TAKE 3286 01:59:54,599 --> 01:59:57,535 OPIOIDS AS PRESCRIBED, HERE 3287 01:59:57,535 --> 01:59:59,637 DEPICTED IN THE -- I DON'T KNOW 3288 01:59:59,637 --> 02:00:00,939 IF YOU CAN SEE THE LASER -- IN 3289 02:00:00,939 --> 02:00:03,007 THE BLUE BARS, OPIOID MISUSING 3290 02:00:03,007 --> 02:00:03,908 CHRONIC PAIN PATIENTS DEPICTED 3291 02:00:03,908 --> 02:00:05,944 IN THE RED BARS, HAD SIGNIFICANT 3292 02:00:05,944 --> 02:00:08,012 BLUNTING OF HIGH FREQUENCY HEART 3293 02:00:08,012 --> 02:00:10,582 RATE VARIABILITY DURING 3294 02:00:10,582 --> 02:00:12,283 REAPPRAISAL, VIEWING POSITIVE 3295 02:00:12,283 --> 02:00:15,019 IMAGES AND SAVORING POSITIVE 3296 02:00:15,019 --> 02:00:15,887 IMAGE, INDICATING THAT THEY HAVE 3297 02:00:15,887 --> 02:00:16,855 A SELECTIVE DEFICIT IN THE 3298 02:00:16,855 --> 02:00:18,156 ABILITY TO SHIFT THEIR EMOTIONS 3299 02:00:18,156 --> 02:00:20,492 IN A POSITIVE DIRECTION. 3300 02:00:20,492 --> 02:00:22,160 AND WE FIND CONVERGING EVIDENCE 3301 02:00:22,160 --> 02:00:23,962 USING EEG HERE IN THE TOP CENTER 3302 02:00:23,962 --> 02:00:25,630 PANEL IN BLUE, OUR BRAINWAVES 3303 02:00:25,630 --> 02:00:27,198 FROM PATIENTS WHO DON'T MISUSE 3304 02:00:27,198 --> 02:00:28,399 OPIOIDS. 3305 02:00:28,399 --> 02:00:29,501 THESE INDIVIDUALS ARE ABLE TO 3306 02:00:29,501 --> 02:00:30,702 DECREASE THEIR BRAIN'S 3307 02:00:30,702 --> 02:00:32,370 REACTIVITY TO NEGATIVE EMOTIONAL 3308 02:00:32,370 --> 02:00:34,305 STIMULI THROUGH REAPPRAISAL. 3309 02:00:34,305 --> 02:00:36,140 BUT BENEATH IN RED YOU CAN SEE 3310 02:00:36,140 --> 02:00:37,275 BRAINWAVES FROM PATIENTS WHO 3311 02:00:37,275 --> 02:00:38,576 MISUSE OPIOIDS. 3312 02:00:38,576 --> 02:00:41,379 NOT ONLY CAN THEY NOT REAPPRAISE 3313 02:00:41,379 --> 02:00:42,914 EFFECTIVELY, BUT REAPPRAISAL 3314 02:00:42,914 --> 02:00:44,482 ACTUALLY BACKFIRES AND 3315 02:00:44,482 --> 02:00:45,717 AGGRAVATES THE NEGATIVE 3316 02:00:45,717 --> 02:00:49,487 EMOTIONAL BRAIN REACTIVITY. 3317 02:00:49,487 --> 02:00:51,289 ALL THE WAY ON RIGHT YOU CAN SEE 3318 02:00:51,289 --> 02:00:54,325 BRAINWAVES DURING POSITIVE 3319 02:00:54,325 --> 02:00:54,926 REGULATION, IN BLUE, PATIENTS 3320 02:00:54,926 --> 02:00:56,895 WHO DON'T MISUSE OPIOIDS. 3321 02:00:56,895 --> 02:00:58,496 THESE INDIVIDUALS WERE ABLE TO 3322 02:00:58,496 --> 02:00:59,998 INCREASE THEIR BRAIN'S RESPONSE 3323 02:00:59,998 --> 02:01:02,200 FROM VIEWING POSITIVE IMAGES TO 3324 02:01:02,200 --> 02:01:06,170 SAVORING POSITIVE IMAGES. 3325 02:01:06,170 --> 02:01:08,940 IN RED YOU CAN SEE BRAINWAVES IN 3326 02:01:08,940 --> 02:01:10,074 PATIENTS WITH OPIOID USE 3327 02:01:10,074 --> 02:01:10,441 DISORDER. 3328 02:01:10,441 --> 02:01:12,377 HERE YOU SEE TOTAL BLUNTING OF 3329 02:01:12,377 --> 02:01:13,545 BRAIN RESPONSE DURING POSITIVE 3330 02:01:13,545 --> 02:01:14,479 EMOTION REGULATION. 3331 02:01:14,479 --> 02:01:16,147 AND THESE DEFICITS IN NEGATIVE 3332 02:01:16,147 --> 02:01:18,816 AND POSITIVE EMOTION REGULATION 3333 02:01:18,816 --> 02:01:20,018 ARE ASSOCIATED WITH HIGHER 3334 02:01:20,018 --> 02:01:21,586 LEVELS OF OPIOID CRAVING AND 3335 02:01:21,586 --> 02:01:23,488 PREDICT OPIOID MISUSE IN THE 3336 02:01:23,488 --> 02:01:23,721 FUTURE. 3337 02:01:23,721 --> 02:01:27,725 SO IT APPEARS AS IF HEDONIC 3338 02:01:27,725 --> 02:01:29,627 DYSREGULATION IS PROPELLING 3339 02:01:29,627 --> 02:01:30,662 OPIOID MISUSE AND ADDICTION. 3340 02:01:30,662 --> 02:01:32,196 IN OTHER WORDS, AS THE 3341 02:01:32,196 --> 02:01:34,232 INDIVIDUAL BECOMES MORE AND MORE 3342 02:01:34,232 --> 02:01:35,400 DEPENDENT ON OPIOIDS JUST TO 3343 02:01:35,400 --> 02:01:36,935 FEEL OKAY, THEY BECOME LESS ABLE 3344 02:01:36,935 --> 02:01:38,870 TO EXTRACT A HEALTHY SENSE OF 3345 02:01:38,870 --> 02:01:40,171 PLEASURE, JOY AND MEANING OUT OF 3346 02:01:40,171 --> 02:01:42,373 EVERYDAY LIFE. 3347 02:01:42,373 --> 02:01:43,474 THIS DRIVES THE PERSON TO TAKE 3348 02:01:43,474 --> 02:01:44,976 HIGHER AND HIGHER DOSES OF THE 3349 02:01:44,976 --> 02:01:47,011 DRUG TO PRESERVE A DWINDLING 3350 02:01:47,011 --> 02:01:49,581 SENSE OF WELL-BEING. 3351 02:01:49,581 --> 02:01:52,150 OVER TIME, OPIOID USE AND PAIN 3352 02:01:52,150 --> 02:01:55,954 BECOME ENTRE ENTRENCHED AS AUTOC 3353 02:01:55,954 --> 02:01:56,888 HABITS. 3354 02:01:56,888 --> 02:01:57,622 ULTIMATELY LEADING TO THE 3355 02:01:57,622 --> 02:01:59,624 DOWNWARD SPIRAL OF LOSS OF SELF 3356 02:01:59,624 --> 02:02:01,893 CONTROL OVER OPIOID USE THAT'S 3357 02:02:01,893 --> 02:02:02,660 CHARACTERISTIC OF OPIOID 3358 02:02:02,660 --> 02:02:04,829 ADDICTION. 3359 02:02:04,829 --> 02:02:07,198 SO WHEN I SAY OPIOID USE AND 3360 02:02:07,198 --> 02:02:09,100 PAIN BECOME ENTANGLED INTO THE 3361 02:02:09,100 --> 02:02:10,001 DEFAULT MODE OF THE SELF, WHAT 3362 02:02:10,001 --> 02:02:12,236 DO I MEAN? 3363 02:02:12,236 --> 02:02:14,439 IF YOU SAY I'M IN PAIN ENOUGH 3364 02:02:14,439 --> 02:02:15,907 TIMES, EVENTUALLY THAT LITTLE 3365 02:02:15,907 --> 02:02:17,709 PREPOSITION "IN" GETS DROPPED 3366 02:02:17,709 --> 02:02:20,645 AND I AM IN PAIN BECOMES I AM 3367 02:02:20,645 --> 02:02:22,580 PAIN, AS ONE'S PRIMARY SENSE OF 3368 02:02:22,580 --> 02:02:25,216 IDENTITY BECOMES FUSED WITH 3369 02:02:25,216 --> 02:02:26,084 PAIN. 3370 02:02:26,084 --> 02:02:27,518 SIMILARLY, REPEATED RUMINATION 3371 02:02:27,518 --> 02:02:28,786 ON ADDICTION-RELATED THOUGHTS 3372 02:02:28,786 --> 02:02:30,221 AND CRAVINGS CAN RESULT IN 3373 02:02:30,221 --> 02:02:32,056 ADDICTION BECOMING ENTANGLED 3374 02:02:32,056 --> 02:02:32,824 INTO THE DEFAULT MODE OF THE 3375 02:02:32,824 --> 02:02:35,293 SELF. 3376 02:02:35,293 --> 02:02:37,195 OVER TIME THE DRUG GAINS PRIMARY 3377 02:02:37,195 --> 02:02:37,795 SELF-RELEVANCE. 3378 02:02:37,795 --> 02:02:39,464 IT BECOMES THE CENTRAL POINT IN 3379 02:02:39,464 --> 02:02:41,265 MEANING OF LIFE AT THE EXPENSE 3380 02:02:41,265 --> 02:02:45,570 OF NATURAL NON-DRUG REWARDS. 3381 02:02:45,570 --> 02:02:46,604 ONE'S IDENTITY BECOMES FUSED 3382 02:02:46,604 --> 02:02:49,774 WITH ADDICTION. 3383 02:02:49,774 --> 02:02:52,243 AND ADDICTION IS KNOWN TO 3384 02:02:52,243 --> 02:02:55,313 INVOLVE -- IN THE DEFAULT MODE 3385 02:02:55,313 --> 02:02:56,514 NETWORK, INCLUDING 3386 02:02:56,514 --> 02:02:57,815 DISCONNECTIVITY BETWEEN THE 3387 02:02:57,815 --> 02:03:00,151 MEDIAL PREFRONTAL CORTEX AND THE 3388 02:03:00,151 --> 02:03:02,520 POSTERIOR CINGULATE CORTEX. 3389 02:03:02,520 --> 02:03:06,224 SO IN SUMMARY, THE OPIOID CRISIS 3390 02:03:06,224 --> 02:03:07,325 APPEARS TO BE LINKED WITH 3391 02:03:07,325 --> 02:03:10,628 DYSREGULATION OF EMOTIONAL 3392 02:03:10,628 --> 02:03:12,163 EXPERIENCE, REWARD AND SELF 3393 02:03:12,163 --> 02:03:13,531 REFERENTIAL MEANING, WHICH 3394 02:03:13,531 --> 02:03:14,966 DRIVES OPIOID DOSE ESCALATION AS 3395 02:03:14,966 --> 02:03:17,135 A MEANS OF SELF-MEDICATING THE 3396 02:03:17,135 --> 02:03:19,904 RESULTING DYSPHORIA. 3397 02:03:19,904 --> 02:03:21,539 THEREFORE, EMOTIONAL WELL-BEING 3398 02:03:21,539 --> 02:03:22,273 INTERVENTIONS MIGHT BE 3399 02:03:22,273 --> 02:03:23,374 PARTICULARLY USEFUL FOR 3400 02:03:23,374 --> 02:03:24,342 IMPROVING OUTCOMES IN THIS 3401 02:03:24,342 --> 02:03:25,610 POPULATION. 3402 02:03:25,610 --> 02:03:27,412 I DEVELOPED A CONCEPTUAL 3403 02:03:27,412 --> 02:03:29,480 FRAMEWORK THAT DESCRIBES THE 3404 02:03:29,480 --> 02:03:31,015 MECHANISMS BY WHICH EMOTIONAL 3405 02:03:31,015 --> 02:03:32,550 WELL-BEING INTERVENTIONS MIGHT 3406 02:03:32,550 --> 02:03:34,719 IMPROVE OUTCOMES IN THIS 3407 02:03:34,719 --> 02:03:37,588 POPULATION. 3408 02:03:37,588 --> 02:03:39,490 BRIEFLY, THE MODEL PROPOSES 3409 02:03:39,490 --> 02:03:42,226 THREE KEY THERAPEUTIC TARGETS 3410 02:03:42,226 --> 02:03:44,962 FROM HEDONIC WELL-BEING TO -- 3411 02:03:44,962 --> 02:03:47,198 NUMBER ONE, SAVORING HEDONIC 3412 02:03:47,198 --> 02:03:48,132 PLEASURE FROM NATURAL HEALTHY 3413 02:03:48,132 --> 02:03:49,200 REWARDS. 3414 02:03:49,200 --> 02:03:52,470 NUMBER TWO, REAPPRAISING 3415 02:03:52,470 --> 02:03:53,905 ADVERSITY -- EXCUSE ME -- 3416 02:03:53,905 --> 02:03:54,872 REAPPRAISING MEANING IN THE FACE 3417 02:03:54,872 --> 02:03:57,775 OF ADVERSITY, AND NUMBER THREE, 3418 02:03:57,775 --> 02:03:59,377 CULTIVATING SELF-TRAN 16 DENSE 3419 02:03:59,377 --> 02:04:05,416 - -- ANDINDUCING A STIMULUS INDT 3420 02:04:05,416 --> 02:04:09,620 FORM OF HAPPINESS. 3421 02:04:09,620 --> 02:04:12,523 I DEVELOPED MINDFULNESS ORIENTED 3422 02:04:12,523 --> 02:04:13,691 RECOVERY ENHANCEMENT AS A MEANS 3423 02:04:13,691 --> 02:04:20,431 OF TARGETING THESE MECHANISMS. 3424 02:04:20,431 --> 02:04:21,833 THE THERAPY COMBINES MINE 3425 02:04:21,833 --> 02:04:23,267 FULLNESS TRAINING, COGNITIVE 3426 02:04:23,267 --> 02:04:25,103 BEHAVIORAL THERAPY AND 3427 02:04:25,103 --> 02:04:26,637 PRINCIPLES FROM POSITIVE 3428 02:04:26,637 --> 02:04:28,339 PSYCHOLOGY INTO A TREATMENT THAT 3429 02:04:28,339 --> 02:04:31,709 CAN SIMULTANEOUSLY ADDRESSEE 3430 02:04:31,709 --> 02:04:36,447 DICKTIVE BEHAVIOR STRESS AND 3431 02:04:36,447 --> 02:04:37,548 CHRONIC PAIN. 3432 02:04:37,548 --> 02:04:40,184 A TEMPORAL BLI DYNAMIC PROCESS 3433 02:04:40,184 --> 02:04:41,753 MODEL OF EMOTION REGULATION THAT 3434 02:04:41,753 --> 02:04:43,321 POSITS THE MECHANISMS BY WHICH 3435 02:04:43,321 --> 02:04:45,423 MINDFULNESS CAN PROMOTE 3436 02:04:45,423 --> 02:04:47,125 EMOTIONAL WELL-BEING AND HUMAN 3437 02:04:47,125 --> 02:04:47,492 FLOURISHING. 3438 02:04:47,492 --> 02:04:49,594 BRIEFLY THE MODEL PROPOSES THAT 3439 02:04:49,594 --> 02:04:51,896 MINDFULNESS ALLOWS ONE TO 3440 02:04:51,896 --> 02:04:54,132 DECENTER FROM STRESS APPRAISALS 3441 02:04:54,132 --> 02:04:57,735 INTO A META COGNITIVE STATE. 3442 02:04:57,735 --> 02:05:00,171 WHICH DISRUPTS NEGATIVE BIASES 3443 02:05:00,171 --> 02:05:01,172 AND EXPANDS THE SCOPE OF 3444 02:05:01,172 --> 02:05:03,107 ATTENTION TO ALLOW ONE TO 3445 02:05:03,107 --> 02:05:04,876 INTEGRATE A BROADENED ARRAY OF 3446 02:05:04,876 --> 02:05:06,077 POSITIVE NEUTRAL AND NEGATIVE 3447 02:05:06,077 --> 02:05:08,412 PIECES OF INFORMATION INTO A 3448 02:05:08,412 --> 02:05:09,914 POSITIVE REAPPRAISAL OF THE 3449 02:05:09,914 --> 02:05:12,917 STRESSFUL SITUATION. 3450 02:05:12,917 --> 02:05:14,418 THE POSITIVE EMOTIONS GENERATED 3451 02:05:14,418 --> 02:05:17,255 FROM THIS PROCESS CAN THEN BE 3452 02:05:17,255 --> 02:05:18,856 SAVORED, WHICH STIMULATES AN 3453 02:05:18,856 --> 02:05:20,258 UPWARD SPIRAL OF POSITIVE AFFECT 3454 02:05:20,258 --> 02:05:22,527 AND COGNITION TOWARDS ADAPTIVE 3455 02:05:22,527 --> 02:05:24,128 ACTIONS AND COMPASSION, AND 3456 02:05:24,128 --> 02:05:25,730 LEADS TO THE SENSE OF 3457 02:05:25,730 --> 02:05:28,232 MEANINGFULNESS IN LIFE. 3458 02:05:28,232 --> 02:05:29,667 THE UPWARD SPIRAL REACHES THE 3459 02:05:29,667 --> 02:05:31,335 APEX IN SELF TRAN 16 DENSE, THE 3460 02:05:31,335 --> 02:05:32,570 SENSE OF BEING CONNECTED TO 3461 02:05:32,570 --> 02:05:38,576 SOMETHING GREATER THAN THE SELF. 3462 02:05:38,576 --> 02:05:40,745 THIS ALSO POSITS RECURSIVE 3463 02:05:40,745 --> 02:05:41,913 FEEDBACK LOOPS WHEREBY HIGHER 3464 02:05:41,913 --> 02:05:43,548 ORDER MECHANISMS CAN ACTIVATE 3465 02:05:43,548 --> 02:05:44,715 LOWER ORDER MECHANISMS TO 3466 02:05:44,715 --> 02:05:46,217 CONTINUE TO DRIVE THE UPWARD 3467 02:05:46,217 --> 02:05:49,453 SPIRAL FORWARD. 3468 02:05:49,453 --> 02:05:51,856 SO GUIDED BY THIS THEORY I 3469 02:05:51,856 --> 02:05:53,057 DEVELOPED MOORE AS A SCWEEBS 3470 02:05:53,057 --> 02:05:54,158 TREATMENT. 3471 02:05:54,158 --> 02:05:56,060 IT BEGINS WITH A FOUNDATION OF 3472 02:05:56,060 --> 02:05:57,328 MINDFULNESS TRAINING BY VIRTUE 3473 02:05:57,328 --> 02:05:58,629 OF STRENGTHENING INTENTIONAL 3474 02:05:58,629 --> 02:06:00,598 CONTROL AND META AWARENESS IS 3475 02:06:00,598 --> 02:06:04,302 USED TO INSINNER JIES MORE 3476 02:06:04,302 --> 02:06:05,803 ELABORATE THERAPEUTIC TECHNIQUES 3477 02:06:05,803 --> 02:06:14,712 AND ULTIMATELY TO LEAD TO SELF 3478 02:06:14,712 --> 02:06:15,046 TRANSCENDENCE. 3479 02:06:15,046 --> 02:06:16,747 THAT ARE IN TURN INTENDED TO 3480 02:06:16,747 --> 02:06:18,015 PRODUCE CLINICALLY SIGNIFICANT 3481 02:06:18,015 --> 02:06:19,750 CHANGE IN A RANGE OF TREATMENT 3482 02:06:19,750 --> 02:06:20,985 TARGETS RELEVANT TO CHRONIC PAIN 3483 02:06:20,985 --> 02:06:24,755 AND OPIOID MISUSE. 3484 02:06:24,755 --> 02:06:25,990 SO I JUST WANT TO FOCUS IN ON 3485 02:06:25,990 --> 02:06:28,326 ONE OF THE THERAPEUTIC 3486 02:06:28,326 --> 02:06:29,093 TECHNIQUES IN THE PROGRAM THAT 3487 02:06:29,093 --> 02:06:30,761 MAKES IT QUITE UNIQUE. 3488 02:06:30,761 --> 02:06:32,897 IN MORE, PATIENTS ARE TAUGHT A 3489 02:06:32,897 --> 02:06:34,265 SAVORING TECHNIQUE IN WHICH 3490 02:06:34,265 --> 02:06:36,334 THEY'RE GUIDE TODAY FOCUS 3491 02:06:36,334 --> 02:06:37,235 MINDFUL AWARENESS ON A BEAUTIFUL 3492 02:06:37,235 --> 02:06:38,836 OBJECT LIKE A ROSE, APPRECIATING 3493 02:06:38,836 --> 02:06:40,204 THE PLEASANT COLORS, TEXTURES 3494 02:06:40,204 --> 02:06:41,739 AND SCENT OF THE FLOWER, AS WELL 3495 02:06:41,739 --> 02:06:42,874 AS THE TOUCH OF THE PETALS 3496 02:06:42,874 --> 02:06:44,408 AGAINST THE SKIN. 3497 02:06:44,408 --> 02:06:45,943 AND DURING THIS PRACTICE, 3498 02:06:45,943 --> 02:06:47,645 PATIENTS ARE GUIDED TO CULTIVATE 3499 02:06:47,645 --> 02:06:49,447 A META COGNITIVE REFLECTIVE 3500 02:06:49,447 --> 02:06:51,148 ATTITUDE AND TO BECOME AWARE OF, 3501 02:06:51,148 --> 02:06:53,718 TO APPRECIATE AND TO AMPLIFY ANY 3502 02:06:53,718 --> 02:06:55,786 POSITIVE EMOTIONS, PLEASURABLE 3503 02:06:55,786 --> 02:06:58,890 BODY SENSATIONS, OR HIGHER ORDER 3504 02:06:58,890 --> 02:07:00,224 AFFECTIVE MEANING ARISING DURING 3505 02:07:00,224 --> 02:07:01,192 THE SAVORING PRACTICE. 3506 02:07:01,192 --> 02:07:02,260 THEN THEY'RE ASKED TO PRACTICE 3507 02:07:02,260 --> 02:07:03,361 THIS TECHNIQUE WITH OTHER 3508 02:07:03,361 --> 02:07:05,129 NATURALLY OCCURRING PLEASANT 3509 02:07:05,129 --> 02:07:07,064 OBJECTS AND EVENTS IN THEIR LIFE 3510 02:07:07,064 --> 02:07:08,733 AS HOMEWORK, AND THIS TECHNIQUE 3511 02:07:08,733 --> 02:07:10,701 IS INTENDED TO AMPLIFY NATURAL 3512 02:07:10,701 --> 02:07:12,436 REWARD PROCESSING IN THE BRAIN, 3513 02:07:12,436 --> 02:07:14,238 BOOST POSITIVE EMOTIONS, ELICIT 3514 02:07:14,238 --> 02:07:17,041 MEANING IN LIFE, AND CULTIVATE 3515 02:07:17,041 --> 02:07:17,975 SELF-TRANSCENDENCE, THE SENSE OF 3516 02:07:17,975 --> 02:07:21,812 INTERCOINTERCONNECTEDNESS, THE E 3517 02:07:21,812 --> 02:07:22,914 BETWEEN THE SELF AND THE WORLD. 3518 02:07:22,914 --> 02:07:24,482 THROUGH AN INTEGRATION OF 3519 02:07:24,482 --> 02:07:27,952 MINDFUL NUSS REAPPRAISAL AND 3520 02:07:27,952 --> 02:07:30,087 SAVORING TECHNIQUES -- THAT HAVE 3521 02:07:30,087 --> 02:07:32,290 BECOME HIJACKED DURING THE 3522 02:07:32,290 --> 02:07:34,592 ALLOSTATIC PROCESS OF DAIX BY 3523 02:07:34,592 --> 02:07:35,693 STRENGTHENING TOP DOWN COGNITIVE 3524 02:07:35,693 --> 02:07:36,894 CONTROL FUNCTIONS TO RESTRUCTURE 3525 02:07:36,894 --> 02:07:38,896 BOTTOM UP REWARD LEARNING FROM 3526 02:07:38,896 --> 02:07:40,798 VALUING DRUGS, BACK TO VALUING 3527 02:07:40,798 --> 02:07:42,767 NATURAL HEALTHY REWARDS. 3528 02:07:42,767 --> 02:07:44,535 AND THIS THERAPEUTIC FOCUS 3529 02:07:44,535 --> 02:07:46,170 ACCORDS WITH WHAT I CALL MY 3530 02:07:46,170 --> 02:07:47,505 RESTRUCTURING REWARD HYPOTHESIS. 3531 02:07:47,505 --> 02:07:48,940 THE NOTION THAT IF WE CAN HELP 3532 02:07:48,940 --> 02:07:51,475 PEOPLE TO SHIFT FROM VALUING THE 3533 02:07:51,475 --> 02:07:54,178 DRUG BACK TO VALUING NATURAL 3534 02:07:54,178 --> 02:07:55,613 HEALTHY REWARD, THIS WILL REDUCE 3535 02:07:55,613 --> 02:07:59,350 KRAICHINREDUCE -- REDUCE CRAVIND 3536 02:07:59,350 --> 02:07:59,817 ADDICTIVE BEHAVIOR. 3537 02:07:59,817 --> 02:08:02,219 AND IN MY VIEW, THIS PROCESS OF 3538 02:08:02,219 --> 02:08:03,688 RESTRUCTURING REWARD LEARNING 3539 02:08:03,688 --> 02:08:05,923 MAY BE THE ESSENTIAL THERAPEUTIC 3540 02:08:05,923 --> 02:08:07,024 PROCESS IN ADDICTION RECOVERY. 3541 02:08:07,024 --> 02:08:08,793 THE PERSON IN RECOVERY MUST 3542 02:08:08,793 --> 02:08:10,394 RELEARN WHAT IS AND IS NOT 3543 02:08:10,394 --> 02:08:11,529 IMPORTANT IN LIFE, WHAT IS AND 3544 02:08:11,529 --> 02:08:13,230 IS NOT MEANINGFUL IN LIFE. 3545 02:08:13,230 --> 02:08:14,565 THEY MUST RECLAIM THAT SENSE OF 3546 02:08:14,565 --> 02:08:16,167 MEANING THAT HAD BEEN STOLEN BY 3547 02:08:16,167 --> 02:08:17,802 THE DRUG, AND REINVESTED BACK 3548 02:08:17,802 --> 02:08:19,370 INTO THE PEOPLE, THE ACTIVITIES 3549 02:08:19,370 --> 02:08:20,671 AND THE VALUES THAT THEY ONCE 3550 02:08:20,671 --> 02:08:24,575 CARED ABOUT. 3551 02:08:24,575 --> 02:08:26,177 SO MORE IS AN EVIDENCE-BASED 3552 02:08:26,177 --> 02:08:26,410 THERAPY. 3553 02:08:26,410 --> 02:08:28,279 TO DATE IT'S BEEN TESTED IN 12 3554 02:08:28,279 --> 02:08:29,413 RANDOMIZED CONTROL TRIALS 3555 02:08:29,413 --> 02:08:30,348 INVOLVING MORE THAN 1300 3556 02:08:30,348 --> 02:08:31,816 PATIENTS. 3557 02:08:31,816 --> 02:08:33,484 AND META-ANALYSIS SHOWS THAT 3558 02:08:33,484 --> 02:08:34,885 MORE SIGNIFICANTLY REDUCES 3559 02:08:34,885 --> 02:08:37,021 ADDICTIVE BEHAVIORS, PSYCH TICK 3560 02:08:37,021 --> 02:08:38,089 SYMPTOMS AND CHRONIC PAIN 3561 02:08:38,089 --> 02:08:39,623 RELATIVE TO A WIDE RANGE OF 3562 02:08:39,623 --> 02:08:41,292 ACTIVE CONTROL CONDITIONS. 3563 02:08:41,292 --> 02:08:43,027 I WANT TO HIGHLIGHT ONE OF THESE 3564 02:08:43,027 --> 02:08:43,761 STUDIES FOR YOU HERE. 3565 02:08:43,761 --> 02:08:45,663 THIS WAS THE LARGEST RANDOMIZED 3566 02:08:45,663 --> 02:08:47,064 CLINICAL TRIAL OF MORE, 3567 02:08:47,064 --> 02:08:47,331 CONDUCTED. 3568 02:08:47,331 --> 02:08:49,867 IT WAS PUBLISHED IN 2022 IN JAMA 3569 02:08:49,867 --> 02:08:50,534 INTERNAL MEDICINE. 3570 02:08:50,534 --> 02:08:54,171 THIS WAS A NIDA R01 FUNDED 3571 02:08:54,171 --> 02:08:54,438 TRIAL. 3572 02:08:54,438 --> 02:08:55,973 THERE WERE 250 PATIENTS WITH 3573 02:08:55,973 --> 02:08:58,342 CHRONIC PAIN, ALL OF WHOM WERE 3574 02:08:58,342 --> 02:09:01,078 PRESCRIBED OPIOIDS AND ALL OF 3575 02:09:01,078 --> 02:09:02,413 WHOM WERE MISUSING AT THE 3576 02:09:02,413 --> 02:09:03,247 BEGINNING OF THE STUDY. 3577 02:09:03,247 --> 02:09:05,750 THEY WERE RANDOMIZED TO RECEIVE 3578 02:09:05,750 --> 02:09:07,118 EIGHT WEEKS OF MORE OR EIGHT 3579 02:09:07,118 --> 02:09:08,986 WEEKS OF STANDARD PSYCHOTHERAPY 3580 02:09:08,986 --> 02:09:10,121 CONTROL CONDITION. 3581 02:09:10,121 --> 02:09:11,055 PATIENTS REPORTED AVERAGE PAIN 3582 02:09:11,055 --> 02:09:12,623 LEVELS OF 5.5 OUT OF 10. 3583 02:09:12,623 --> 02:09:15,760 THEY WERE TAKING HIGH OPIOID 3584 02:09:15,760 --> 02:09:17,762 DOSES AT BASELINE. 3585 02:09:17,762 --> 02:09:19,830 THREE QUARTERS OF THE SAMPLE 3586 02:09:19,830 --> 02:09:20,564 REPORTED HAVING TWO OR MORE 3587 02:09:20,564 --> 02:09:22,133 CHRONIC OVERLAPPING PAIN 3588 02:09:22,133 --> 02:09:23,200 CONDITIONS, AND THERE WERE HIGH 3589 02:09:23,200 --> 02:09:24,702 RATES OF PSYCHOPATHOLOGY IN THE 3590 02:09:24,702 --> 02:09:27,972 SAMPLE AS WELL. 3591 02:09:27,972 --> 02:09:29,573 IN SUMMARY OF THE FINDINGS, MORE 3592 02:09:29,573 --> 02:09:32,410 REDUCED OPIOID MISUSE BY 45% AT 3593 02:09:32,410 --> 02:09:34,245 THE NINE MONTH FOLLOW-UP POINT. 3594 02:09:34,245 --> 02:09:35,780 NEARLY TRIPLING THE EFFECT OF 3595 02:09:35,780 --> 02:09:39,216 STANDARD GROUP THERAPY. 3596 02:09:39,216 --> 02:09:41,585 MORE ALSO PRODUCED SIGNIFICANTLY 3597 02:09:41,585 --> 02:09:42,319 CLINICAL REDUCTIONS IN PAPER 3598 02:09:42,319 --> 02:09:45,356 SYMPTOMS THAT LASTED THROUGH THE 3599 02:09:45,356 --> 02:09:46,724 NINE-MONTH FOLLOW-UP. 3600 02:09:46,724 --> 02:09:48,259 50% OF PATIENTS TREATED WITH 3601 02:09:48,259 --> 02:09:50,428 MORE REPORTED CLINICALLY 3602 02:09:50,428 --> 02:09:51,829 SIGNIFICANT REDUCTIONS IN 3603 02:09:51,829 --> 02:09:52,696 CHRONIC PAIN. 3604 02:09:52,696 --> 02:09:56,167 MORE IMPROVED DIMENSIONS OF 3605 02:09:56,167 --> 02:09:57,568 EMOTIONAL WELL-BEING. 3606 02:09:57,568 --> 02:09:59,270 MORE LED TO CLINICALLY 3607 02:09:59,270 --> 02:10:00,905 SIGNIFICANT REDUCTIONS IN PTSD 3608 02:10:00,905 --> 02:10:02,373 SYMPTOMS, AND MORE ENHANCED 3609 02:10:02,373 --> 02:10:03,808 POSITIVE EMOTIONS, MEANING IN 3610 02:10:03,808 --> 02:10:06,110 LIFE AND SELF TRANSCENDENCE. 3611 02:10:06,110 --> 02:10:07,545 THESE DATA SUGGEST THAT MORE IS 3612 02:10:07,545 --> 02:10:11,582 A BROAD SPECTRUM TREATMENT THAT 3613 02:10:11,582 --> 02:10:12,817 CAN SIMULTANEOUSLY ADDRESS 3614 02:10:12,817 --> 02:10:14,085 ADDICTION, CHRONIC PAIN AND THE 3615 02:10:14,085 --> 02:10:15,586 PSYCHIATRIC CONDITIONS THAT 3616 02:10:15,586 --> 02:10:17,955 OFTEN CO-OCCUR WITH THESE 3617 02:10:17,955 --> 02:10:19,123 PROBLEMS. 3618 02:10:19,123 --> 02:10:22,426 SO WE WANTED TO KNOW WHETHER 3619 02:10:22,426 --> 02:10:24,061 MORE COULD ACTUALLY MODULATE 3620 02:10:24,061 --> 02:10:26,497 REWARD RESPONSES IN THE BRAIN TO 3621 02:10:26,497 --> 02:10:29,767 DRUG-RELATED CUES, SO IN A 3622 02:10:29,767 --> 02:10:31,102 SEPARATE MECHANISTIC EXPERIMENT, 3623 02:10:31,102 --> 02:10:32,103 WE BROUGHT PATIENTS INTO THE LAB 3624 02:10:32,103 --> 02:10:34,572 AND HAD THEM VIEW OPIOID 3625 02:10:34,572 --> 02:10:35,639 PHOTOGRAPHS ON THE COMPUTER 3626 02:10:35,639 --> 02:10:37,641 SCREEN WHILE WE MEASURED THEIR 3627 02:10:37,641 --> 02:10:39,076 BRAIN ACTIVITY WITH EEG. 3628 02:10:39,076 --> 02:10:40,978 WE FOUND THAT MORE LED TO 3629 02:10:40,978 --> 02:10:43,681 MASSIVE REDRUXES IN BRAIN DRUG 3630 02:10:43,681 --> 02:10:45,683 CUE REACTIVITY AS INDICATED BY 3631 02:10:45,683 --> 02:10:46,750 THE LATE POSITIVE POTENTIAL OF 3632 02:10:46,750 --> 02:10:47,284 THE EEG. 3633 02:10:47,284 --> 02:10:49,253 THESE ARE THE FIRST DATA FROM A 3634 02:10:49,253 --> 02:10:50,121 RANDOMIZED CONTROL TRIAL SHOWING 3635 02:10:50,121 --> 02:10:52,089 A MINDFULNESS BASED INTD VENGS 3636 02:10:52,089 --> 02:10:53,858 CAN REDUCE DRUG CUE REACTIVITY 3637 02:10:53,858 --> 02:10:54,492 IN THE BRAIN. 3638 02:10:54,492 --> 02:10:56,293 SO GIVEN THEIR NOVELTY AND 3639 02:10:56,293 --> 02:10:56,927 SIGNIFICANCE, THEY WERE 3640 02:10:56,927 --> 02:10:58,162 PUBLISHED IN SCIENCE ADVANCES A 3641 02:10:58,162 --> 02:10:59,797 COUPLE OF YEARS AGO. 3642 02:10:59,797 --> 02:11:01,732 BUT WE WONDERED IF MORE CAN 3643 02:11:01,732 --> 02:11:03,934 REDUCE THE BRAIN'S REACTIVITY TO 3644 02:11:03,934 --> 02:11:06,036 DRUG-RELATED CUES, CAN IT 3645 02:11:06,036 --> 02:11:07,471 INCREASE REWARD RESPONSES TO 3646 02:11:07,471 --> 02:11:09,640 NATURAL HEALTHY REWARD CUES? 3647 02:11:09,640 --> 02:11:11,742 AND SO IN A SEPARATE RANDOMIZED 3648 02:11:11,742 --> 02:11:12,710 MECHANISTIC EXPERIMENT, WE FOUND 3649 02:11:12,710 --> 02:11:15,212 THAT MORE INCREASED THE LATE 3650 02:11:15,212 --> 02:11:16,780 POSITIVE POTENTIAL OF THE EEG AS 3651 02:11:16,780 --> 02:11:19,083 WELL AS SKIN CONDUCTANCE 3652 02:11:19,083 --> 02:11:20,618 RESPONSES DURING VIEWING AND 3653 02:11:20,618 --> 02:11:23,454 SAVORING OF NATURAL HEALTHY 3654 02:11:23,454 --> 02:11:24,455 REWARD CUES, SO IMAGING OF 3655 02:11:24,455 --> 02:11:26,257 SMILING BABY, LOVERS HOLDING 3656 02:11:26,257 --> 02:11:28,559 HANDS, BEAUTIFUL SUNSETS. 3657 02:11:28,559 --> 02:11:30,694 AND MORE ALSO INCREASED POSITIVE 3658 02:11:30,694 --> 02:11:32,296 AFFECTIVE RESPONSES TO THESE 3659 02:11:32,296 --> 02:11:33,330 CUES. 3660 02:11:33,330 --> 02:11:35,432 AND THE EFFECT OF MORE ON 3661 02:11:35,432 --> 02:11:38,102 REDUCING OPIOID MISUSE WAS 3662 02:11:38,102 --> 02:11:38,936 STATISTICALLY MEDIATED BY 3663 02:11:38,936 --> 02:11:41,639 INCREASES IN THIS NATURAL REWARD 3664 02:11:41,639 --> 02:11:42,940 RESPONSIVENESS, PROVIDING STRONG 3665 02:11:42,940 --> 02:11:46,043 SUPPORT FOR THE RESTRUCTURING 3666 02:11:46,043 --> 02:11:48,145 REWARD HYPOTHESIS. 3667 02:11:48,145 --> 02:11:50,214 BUT WE'VE ALSO SHOWN THAT MORE 3668 02:11:50,214 --> 02:11:52,149 CAN INCREASE INTERNAL SELF 3669 02:11:52,149 --> 02:11:55,819 GENERATION OF HEDONIC 3670 02:11:55,819 --> 02:11:56,353 WELL-BEING. 3671 02:11:56,353 --> 02:11:58,689 THIS IS A COMPUTERIZED BODY MAP. 3672 02:11:58,689 --> 02:12:00,791 ON THIS BODY MAP PATIENTS LOCATE 3673 02:12:00,791 --> 02:12:02,026 PLEASANT AND UNPLEASANT 16 3674 02:12:02,026 --> 02:12:02,626 VAITIONS. 3675 02:12:02,626 --> 02:12:04,061 PLEASANT SENSATIONS ARE 3676 02:12:04,061 --> 02:12:05,496 REPRESENTED IN BLUE. 3677 02:12:05,496 --> 02:12:06,463 UNPLEASANT SENSATIONS ARE 3678 02:12:06,463 --> 02:12:07,264 REPRESENTED IN RED. 3679 02:12:07,264 --> 02:12:10,234 THIS IS A ONE-SIDED BODY MAP SO 3680 02:12:10,234 --> 02:12:12,303 IT REPRESENTS THE SUMMATION OF 3681 02:12:12,303 --> 02:12:13,003 SENSATIONS ON THE BACK AND FRONT 3682 02:12:13,003 --> 02:12:13,837 OF THE BODY. 3683 02:12:13,837 --> 02:12:15,406 YOU CAN SEE HERE THAT MORE 3684 02:12:15,406 --> 02:12:19,176 MASSIVELY INCREASES PLEASANT 3685 02:12:19,176 --> 02:12:21,879 SENSATIONS IN THE BODY, AND ALSO 3686 02:12:21,879 --> 02:12:23,347 RADICALLY SHIFTS THE RAISH YOAL 3687 02:12:23,347 --> 02:12:24,815 OF PLEASANT TO UNPLEASANT 3688 02:12:24,815 --> 02:12:25,216 SENSATIONS. 3689 02:12:25,216 --> 02:12:27,384 AT THE BEGINNING OF THE STUDY, 3690 02:12:27,384 --> 02:12:29,453 PATIENTS REPORTED ABOUT ONE 3691 02:12:29,453 --> 02:12:30,621 PLEASANT 16 VAITION FOR EVERY 3692 02:12:30,621 --> 02:12:32,189 FOUR UNPLEASANT SENSATIONS. 3693 02:12:32,189 --> 02:12:33,757 AND I FIND THAT REALLY SAD. 3694 02:12:33,757 --> 02:12:35,025 IT JUST SPEAKS TO HOW MUCH THESE 3695 02:12:35,025 --> 02:12:36,894 FOLKS WERE SUFFERING. 3696 02:12:36,894 --> 02:12:38,195 BUT BY SIX MONTHS AFTER BEING 3697 02:12:38,195 --> 02:12:40,831 TREATED WITH MORE, PATIENTS 3698 02:12:40,831 --> 02:12:41,932 REPORTED TWO PLEASANT SENSATIONS 3699 02:12:41,932 --> 02:12:47,304 FOR EVERY ONE UNPLEASANT 3700 02:12:47,304 --> 02:12:50,040 SENSATION, DEMONSTRATING MORE 3701 02:12:50,040 --> 02:12:53,344 TEACHES -- THEREBY SHIFTS THE 3702 02:12:53,344 --> 02:12:58,082 BODY FROM BEING A PLACE OF AN 3703 02:12:58,082 --> 02:12:59,483 ANGUISH TO BECOMING A PLACE OF 3704 02:12:59,483 --> 02:12:59,917 REFUGE. 3705 02:12:59,917 --> 02:13:02,419 BUT WE WONDERED, CAN THE 3706 02:13:02,419 --> 02:13:04,421 SELF-GENERATION OF HEDONIC 3707 02:13:04,421 --> 02:13:07,057 WELL-BEING PROMOTE -- MEANING. 3708 02:13:07,057 --> 02:13:09,560 SO IN NEW DATA COMING FROM MY 3709 02:13:09,560 --> 02:13:11,328 PRIMARY CARE R01 FUNDED STUDY OF 3710 02:13:11,328 --> 02:13:13,497 MORE, WE FOUND THAT MORE 3711 02:13:13,497 --> 02:13:15,266 INCREASES THE CAPACITY TO SAVOR 3712 02:13:15,266 --> 02:13:16,667 NATURAL HEALTHY REWARDS AS 3713 02:13:16,667 --> 02:13:17,768 INDICATED BY THE LATE POSITIVE 3714 02:13:17,768 --> 02:13:19,870 POTENTIAL OF THE EEG. 3715 02:13:19,870 --> 02:13:21,505 AND GREATER INCREASES IN 3716 02:13:21,505 --> 02:13:23,140 SAVORING EFFICACY WERE 3717 02:13:23,140 --> 02:13:24,708 ASSOCIATED WITH LARGER INCREASES 3718 02:13:24,708 --> 02:13:26,377 IN MEANING IN LIFE FOLLOWING 3719 02:13:26,377 --> 02:13:28,112 TREATMENT WITH MORE. 3720 02:13:28,112 --> 02:13:29,546 THESE DATA SUPPORT THE 3721 02:13:29,546 --> 02:13:31,949 MINDFULNESS TO MEANING THEORY, 3722 02:13:31,949 --> 02:13:33,684 PARTICULARLY THE SPECIFIC 3723 02:13:33,684 --> 02:13:34,918 HYPOTHESIS THAT SAVORING CAN 3724 02:13:34,918 --> 02:13:36,320 STIMULATE AN UPWARD SPIRAL 3725 02:13:36,320 --> 02:13:40,958 TOWARDS MEANING IN LIFE. 3726 02:13:40,958 --> 02:13:43,894 SO WE WANTED TO DELVE INTO THIS 3727 02:13:43,894 --> 02:13:46,397 PATHWAY MORE DEEPLY. 3728 02:13:46,397 --> 02:13:48,732 MY COLLEAGUE AND I ANALYZED 3729 02:13:48,732 --> 02:13:49,933 ECOLOGICAL MOMENTARY ASSESSMENT 3730 02:13:49,933 --> 02:13:51,135 DATA FROM THIS TRIAL. 3731 02:13:51,135 --> 02:13:53,304 IN THE TRIAL, PARTICIPANTS 3732 02:13:53,304 --> 02:13:54,638 COMPLETED 180 EM AMOUNT OF TIME 3733 02:13:54,638 --> 02:13:56,073 POINTS OVER 60 DAYS. 3734 02:13:56,073 --> 02:13:57,641 AND WE FOUND THAT MORE WAS 3735 02:13:57,641 --> 02:14:00,244 INCREASING THE EXA CAPACITY TO 3736 02:14:00,244 --> 02:14:01,245 DECENTER FROM NEGATIVE THOWTSZ 3737 02:14:01,245 --> 02:14:04,515 AND EMOTIONS OVER TIME. 3738 02:14:04,515 --> 02:14:07,051 MORE ALSO PRESERVED POSITIVE 3739 02:14:07,051 --> 02:14:08,585 REAPPRAISAL CAPACITY WHEREAS 3740 02:14:08,585 --> 02:14:09,987 REAPPRAISAL CAPACITY DECAYED IN 3741 02:14:09,987 --> 02:14:10,754 THE CONTROL GROUP. 3742 02:14:10,754 --> 02:14:12,323 MORE LED TO LARGE INCREASES IN 3743 02:14:12,323 --> 02:14:13,924 POSITIVE AFFECT, AND SAVORING 3744 02:14:13,924 --> 02:14:17,961 OVER TIME. 3745 02:14:17,961 --> 02:14:19,763 USING MULTILEVEL MEDIATION 3746 02:14:19,763 --> 02:14:21,665 ANALYSIS WITH LAGGED REGRESSION 3747 02:14:21,665 --> 02:14:23,100 COEFFICIENTS, WE TESTED THE 3748 02:14:23,100 --> 02:14:25,369 PRIMARY MINDFUL REAPPRAISAL 3749 02:14:25,369 --> 02:14:26,837 HYPOTHESIS OF THE MINDFULNESS TO 3750 02:14:26,837 --> 02:14:27,571 MEANING THEORY. 3751 02:14:27,571 --> 02:14:29,073 WE FOUND THAT EXTENT TO WHICH 3752 02:14:29,073 --> 02:14:30,641 YOU DECENTER TODAY WILL PREDICT 3753 02:14:30,641 --> 02:14:32,609 YOUR POSITIVE AFFECT TWO DAYS 3754 02:14:32,609 --> 02:14:35,446 FROM NOW BY IMPROVING POSITIVE 3755 02:14:35,446 --> 02:14:37,915 REAPPRAISAL CAPACITY TOMORROW. 3756 02:14:37,915 --> 02:14:40,384 WE CONDUCTED COUNT COUNTERFACTUL 3757 02:14:40,384 --> 02:14:41,819 MODELS AND FOUND THAT THE 3758 02:14:41,819 --> 02:14:42,519 INDIRECT EFFECTS OF ALL THE 3759 02:14:42,519 --> 02:14:43,854 MODELS WERE SIGNIFICANT. 3760 02:14:43,854 --> 02:14:46,757 AND THUS, DECENTERING POSITIVE 3761 02:14:46,757 --> 02:14:47,791 REAPPRAISAL AND POSITIVE AFFECT 3762 02:14:47,791 --> 02:14:49,193 APPEAR TO KINDLE ONE ANOTHER 3763 02:14:49,193 --> 02:14:51,061 INTO AN UPWARD SPIRAL THAT 3764 02:14:51,061 --> 02:14:55,632 PROPELS ITSELF OVER TIME. 3765 02:14:55,632 --> 02:14:57,434 FROM A PSYCHOPHYSIOLOGICAL 3766 02:14:57,434 --> 02:14:58,202 PERSPECTIVE, WE'VE SHOWN THAT 3767 02:14:58,202 --> 02:15:00,170 MORE INCREASES REAPPRAISAL 3768 02:15:00,170 --> 02:15:03,474 EFFICACY AS INDICATED BY SKIN 3769 02:15:03,474 --> 02:15:04,775 CONDUCT DANCE RESPONSES DURING 3770 02:15:04,775 --> 02:15:06,076 THE EMOTION REGULATION TASK. 3771 02:15:06,076 --> 02:15:07,878 AND THE EFFECT OF MORE ON 3772 02:15:07,878 --> 02:15:10,080 REDUCING EMOTIONAL DISTRESS IS 3773 02:15:10,080 --> 02:15:11,048 STATISTICALLY MEDIATED BY 3774 02:15:11,048 --> 02:15:12,750 INCREASES IN REAPPRAISAL 3775 02:15:12,750 --> 02:15:17,221 CAPACITY. 3776 02:15:17,221 --> 02:15:19,523 BUT IN A NEW R01 FUNDED STUDY 3777 02:15:19,523 --> 02:15:20,824 THAT WE JUST COMPLETED COMPARING 3778 02:15:20,824 --> 02:15:22,926 MORE TO COGNITIVE BEHAVIORAL 3779 02:15:22,926 --> 02:15:23,961 THERAPY FOR PEOPLE WHO ARE 3780 02:15:23,961 --> 02:15:25,929 ADDICTED TO CIGARETTES, WE FOUND 3781 02:15:25,929 --> 02:15:29,433 THAT MORE OUTPERFORMS CBT IN 3782 02:15:29,433 --> 02:15:31,068 IMPROVING REAPPRAISAL EFFICACY 3783 02:15:31,068 --> 02:15:32,436 AS MEASURED BY AFFECTIVE 3784 02:15:32,436 --> 02:15:33,637 RESPONSES ON THE EMOTION 3785 02:15:33,637 --> 02:15:36,273 REGULATION TASK. 3786 02:15:36,273 --> 02:15:37,775 AND GREATER INCREASES IN 3787 02:15:37,775 --> 02:15:38,842 REAPPRAISAL EFFICACY WERE 3788 02:15:38,842 --> 02:15:40,177 ASSOCIATED WITH LOWER LEVELS OF 3789 02:15:40,177 --> 02:15:42,246 SMOKING CUE-INDUCED CRAVING, 3790 02:15:42,246 --> 02:15:43,280 SUGGESTING THAT TEACHING PEOPLE 3791 02:15:43,280 --> 02:15:44,848 TO REAPPRAISE THE MEANING OF 3792 02:15:44,848 --> 02:15:47,184 ADVERSE STIMULI MAY ACTUALLY 3793 02:15:47,184 --> 02:15:50,788 HAVE ANTIADDICTIVE PROPERTIES. 3794 02:15:50,788 --> 02:15:53,090 ABOUT YOU WHAT ABOUT THE THIRD 3795 02:15:53,090 --> 02:15:54,658 MECHANISM, CULTIVATING SELF 3796 02:15:54,658 --> 02:15:55,826 TRANSCENDENCE? 3797 02:15:55,826 --> 02:15:57,661 THE ORIGINAL PURPOSE OF 3798 02:15:57,661 --> 02:15:59,263 MINDFULNESS WAS NOT MERELY TO 3799 02:15:59,263 --> 02:16:01,498 TEACH PEOPLE TO REGULATE THEIR 3800 02:16:01,498 --> 02:16:02,566 EMOTIONS BUT RATHER IT WAS TO 3801 02:16:02,566 --> 02:16:04,868 HELP THEM GAIN INSIGHT INTO THE 3802 02:16:04,868 --> 02:16:06,303 FUNDAMENTAL NON-DUALITY BETWEEN 3803 02:16:06,303 --> 02:16:07,638 THE SELF AND THE WORLD, ALSO 3804 02:16:07,638 --> 02:16:09,273 KNOWN AS SELF-TRANSCENDENCE IN 3805 02:16:09,273 --> 02:16:10,941 THE PSYCHOLOGICAL LITERATURE. 3806 02:16:10,941 --> 02:16:13,410 WE TYPICALLY EXPERIENCE 3807 02:16:13,410 --> 02:16:15,646 OURSELVES AS AN ISOLATED SUBJECT 3808 02:16:15,646 --> 02:16:17,781 IDENTIFIED BY OUR BODIES AND 3809 02:16:17,781 --> 02:16:18,715 ENCAPSULATED BY OUR SKIN, BUT 3810 02:16:18,715 --> 02:16:21,051 THERE CAN BE MOMENTS WHEN THE 3811 02:16:21,051 --> 02:16:22,953 NORMAL SUBJECT OBJECT DUALITY 3812 02:16:22,953 --> 02:16:23,987 BEGINS TO FADE AND WE FEEL A 3813 02:16:23,987 --> 02:16:26,023 SENSE OF CLOSENESS OR 3814 02:16:26,023 --> 02:16:26,857 INTERCONNECTEDNESS OR EVEN 3815 02:16:26,857 --> 02:16:27,858 ONENESS WITH THE WORLD AROUND 3816 02:16:27,858 --> 02:16:28,559 US. 3817 02:16:28,559 --> 02:16:29,726 AND DURING THESE MOMENTS, WE'RE 3818 02:16:29,726 --> 02:16:31,295 OFTEN FILLED WITH A PROFOUND 3819 02:16:31,295 --> 02:16:34,698 SENSE OF PEACE, LOVE, OR EVEN 3820 02:16:34,698 --> 02:16:35,132 BLISS. 3821 02:16:35,132 --> 02:16:36,300 AND THESE EXPERIENCES CAN BE 3822 02:16:36,300 --> 02:16:37,768 AMONG THE MOST MEANINGFUL IN A 3823 02:16:37,768 --> 02:16:41,505 PERSON'S LIFE. 3824 02:16:41,505 --> 02:16:42,406 NE CAN HAPPEN WHEN THEY'RE AT 3825 02:16:42,406 --> 02:16:43,507 THE CONCERT OF YOUR FAVORITE 3826 02:16:43,507 --> 02:16:45,008 BAND AND YOU BECOME SO ABSORBED 3827 02:16:45,008 --> 02:16:46,743 IN THE MUSIC AND THE LIGHTS THAT 3828 02:16:46,743 --> 02:16:47,878 YOU LOSE ALL SENSE OF YOURSELF 3829 02:16:47,878 --> 02:16:49,613 AND YOU MELT INTO THE THRILLING 3830 02:16:49,613 --> 02:16:53,016 BLISS OF THE MUSICAL NOTES. 3831 02:16:53,016 --> 02:16:54,184 THESE EXPERIENCES CAN HAPPEN 3832 02:16:54,184 --> 02:16:55,686 WHEN YOU'RE WATCHING A BEAUTIFUL 3833 02:16:55,686 --> 02:16:58,188 SUNSET AT SEA. 3834 02:16:58,188 --> 02:16:59,623 AND THE SENSE OF SELF BECOMES 3835 02:16:59,623 --> 02:17:01,358 QUIET AND YOU FEEL A SENSE OF 3836 02:17:01,358 --> 02:17:02,159 CONNECTEDNESS WITH ALL THINGS 3837 02:17:02,159 --> 02:17:04,027 AND A SENSE OF EXPANSIVENESS 3838 02:17:04,027 --> 02:17:06,363 BEYOND THE HORIZON. 3839 02:17:06,363 --> 02:17:08,031 THESE EXPERIENCES CAN OCCUR 3840 02:17:08,031 --> 02:17:10,067 UNDER THE INFLUENCE OF 3841 02:17:10,067 --> 02:17:11,935 PSILOCYBIN AND LSD. 3842 02:17:11,935 --> 02:17:14,037 AND THEY CAN AND DO OCCUR DURING 3843 02:17:14,037 --> 02:17:16,139 MEDITATION. 3844 02:17:16,139 --> 02:17:17,908 WE NEED TO BE ABLE TO QUANTIFY 3845 02:17:17,908 --> 02:17:19,409 THESE STATES SO IF YOU WANT TO 3846 02:17:19,409 --> 02:17:21,078 UNDERSTAND THEM, SCIENTIFICALLY, 3847 02:17:21,078 --> 02:17:22,813 SO TO DO SO, MY COLLEAGUES AND I 3848 02:17:22,813 --> 02:17:25,182 DEVELOPED THE NON-DUAL AWARENESS 3849 02:17:25,182 --> 02:17:27,885 DIMENSIONAL ASSESSMENT OR NADA 3850 02:17:27,885 --> 02:17:33,223 USING A PSYCHOMETRIC APPROACH, 3851 02:17:33,223 --> 02:17:34,424 THE CONSTRUCT OF MINDFULNESS. 3852 02:17:34,424 --> 02:17:36,226 WE FACTOR ANALYZED SIX EXISTING 3853 02:17:36,226 --> 02:17:38,595 SCALES AND FOUND THAT THE NADA 3854 02:17:38,595 --> 02:17:40,063 HAD EXCELLENT PSYCHOMETRIC 3855 02:17:40,063 --> 02:17:42,165 CHARACTERISTICS AND STRONG 3856 02:17:42,165 --> 02:17:44,601 CONVERGENT AND DISCRIMINATE 3857 02:17:44,601 --> 02:17:46,136 VALIDITY SUGGESTING WE HAD 3858 02:17:46,136 --> 02:17:47,437 DEVELOPED A SENSITIVE AND 3859 02:17:47,437 --> 02:17:49,406 RELIABLE MEASURE OF 3860 02:17:49,406 --> 02:17:50,407 SELF-TRANSCENDENCE. 3861 02:17:50,407 --> 02:17:52,075 USING THE NADA, WE FOUND MORE 3862 02:17:52,075 --> 02:17:53,610 LED TO SIGNIFICANT INKREES IN 3863 02:17:53,610 --> 02:17:54,611 SELF TRANSCENDENCE AND BLISS 3864 02:17:54,611 --> 02:17:58,282 THROUGH A NINE-MONTH FOLLOW-UP 3865 02:17:58,282 --> 02:17:59,116 POINT. 3866 02:17:59,116 --> 02:18:02,419 WE WONDERED HOW EXPERIENCES OF 3867 02:18:02,419 --> 02:18:03,720 SELF-TRANSCENDENCE ACHIEVED 3868 02:18:03,720 --> 02:18:05,289 DURING DEEP MEDITATIVE STATES 3869 02:18:05,289 --> 02:18:07,658 MIGHT ACTUALLY IMPACT ADDICTIVE 3870 02:18:07,658 --> 02:18:08,525 BEHAVIOR. 3871 02:18:08,525 --> 02:18:10,093 SO IN ANOTHER MECHANISTIC 3872 02:18:10,093 --> 02:18:11,128 EXPERIMENT, WE BROUGHT PATIENTS 3873 02:18:11,128 --> 02:18:12,863 INTO THE LAB AND HAD THEM 3874 02:18:12,863 --> 02:18:14,665 PRACTICE MINDFULNESS MEDITATION 3875 02:18:14,665 --> 02:18:16,433 WHILE WE RECORDED THEIR BRAIN 3876 02:18:16,433 --> 02:18:17,768 ACTIVITY WITH EEG. 3877 02:18:17,768 --> 02:18:19,770 WE FOUND PATIENTS TREATED WITH 3878 02:18:19,770 --> 02:18:20,938 MORE SHOWED SIGNIFICANT 3879 02:18:20,938 --> 02:18:23,173 INCREASES IN FRONTAL MIDLINE 3880 02:18:23,173 --> 02:18:24,942 THETA EEG POWER AND COHERENCE 3881 02:18:24,942 --> 02:18:26,610 DURING MINDFULNESS MEDITATION. 3882 02:18:26,610 --> 02:18:28,712 HIGHER LEVELS OF THETA WERE 3883 02:18:28,712 --> 02:18:30,514 ASSOCIATED WITH MORE INTENSE 3884 02:18:30,514 --> 02:18:32,316 SELF TRANSCENDENT EXPERIENCES 3885 02:18:32,316 --> 02:18:34,785 AND MEDIATED THE EFFECT OF MORE 3886 02:18:34,785 --> 02:18:36,853 ON REDUCING OPIOID USE THROUGH A 3887 02:18:36,853 --> 02:18:38,388 FOUR-MONTH FOLLOW-UP POINT. 3888 02:18:38,388 --> 02:18:41,458 FRONTAL MIDLINE THETA IS A 3889 02:18:41,458 --> 02:18:41,959 WELL-KNOWN BIOMARKER OF 3890 02:18:41,959 --> 02:18:43,727 COGNITIVE CONTROL BUT IT'S ALSO 3891 02:18:43,727 --> 02:18:45,062 INVERSELY ASSOCIATED WITH 3892 02:18:45,062 --> 02:18:46,730 ACTIVATION IN THE DEFAULT MODE 3893 02:18:46,730 --> 02:18:48,632 NETWORK OF THE BRAIN. 3894 02:18:48,632 --> 02:18:50,567 AND FRONTAL MIDLINE THETA 3895 02:18:50,567 --> 02:18:51,602 INCREASES DURING STATES OF FLOW, 3896 02:18:51,602 --> 02:18:54,004 WHEN THE SENSE OF SELF IS 3897 02:18:54,004 --> 02:18:55,572 TEMPORARILY SUSPENDED AND 3898 02:18:55,572 --> 02:18:56,974 TRANSCENDED DURING DEEP 3899 02:18:56,974 --> 02:18:57,908 COGNITIVE ABSORPTION WITH 3900 02:18:57,908 --> 02:19:00,477 ONGOING ACTIVITY. 3901 02:19:00,477 --> 02:19:02,112 SO THESE DATA SUGGEST THAT 3902 02:19:02,112 --> 02:19:03,513 MINDFULNESS INDUCED SELF 3903 02:19:03,513 --> 02:19:04,247 TRANSCENDENCE MAY PROVIDE A 3904 02:19:04,247 --> 02:19:06,283 MEANS OF INDODGE JUST THETA 3905 02:19:06,283 --> 02:19:08,385 STIMULATION AND, THERE BY 3906 02:19:08,385 --> 02:19:11,989 ENHANCE INHIBITORY CONTROL OVER 3907 02:19:11,989 --> 02:19:12,956 ADDICTIVE BEHAVIOR. 3908 02:19:12,956 --> 02:19:14,625 WE RECENTLY REPLICATED THESE 3909 02:19:14,625 --> 02:19:19,262 RESULTS IN THE LARGEST STUDY. 3910 02:19:19,262 --> 02:19:21,198 IN A SAMPLE OF 165 CHRONIC 3911 02:19:21,198 --> 02:19:22,699 OPIOID USERS, WE BROUGHT THEM 3912 02:19:22,699 --> 02:19:24,735 INTO THE LAB AND AGAIN HAD THEM 3913 02:19:24,735 --> 02:19:25,936 PRACTICE MINDFULNESS MEDITATION 3914 02:19:25,936 --> 02:19:27,604 WHILE WE RECORDED THEIR BRAIN 3915 02:19:27,604 --> 02:19:29,506 ACTIVITY WITH EEG. 3916 02:19:29,506 --> 02:19:30,674 AND I LOVE DATA LIKE THIS, YOU 3917 02:19:30,674 --> 02:19:32,342 DON'T NEED ANY STATISTICS AT ALL 3918 02:19:32,342 --> 02:19:33,810 SO HERE'S THE GAME. 3919 02:19:33,810 --> 02:19:35,078 WHICH ONE OF THESE FOUR BRAIN 3920 02:19:35,078 --> 02:19:38,815 MAPS IS NOT LIKE THE OTHER? 3921 02:19:38,815 --> 02:19:41,118 THAT'S THE BRAIN AFTER EAT WEEKS 3922 02:19:41,118 --> 02:19:42,352 OF MORE AND THAT REMINDS ME OF 3923 02:19:42,352 --> 02:19:43,420 THAT OLD COMMERCIAL, THIS IS 3924 02:19:43,420 --> 02:19:44,421 YOUR BRAIN ON DRUGS. 3925 02:19:44,421 --> 02:19:48,525 REMEMBER THE EGG FRIDAY EGG FRYE 3926 02:19:48,525 --> 02:19:49,526 PAN? 3927 02:19:49,526 --> 02:19:50,494 THIS IS YOUR BRAIN ON MORE. 3928 02:19:50,494 --> 02:19:52,396 MORE LED TO MASSIVE INCREASES IN 3929 02:19:52,396 --> 02:19:54,998 FRONTAL MIDLINE THETA EEG 3930 02:19:54,998 --> 02:19:56,333 ACTIVITY AND ONCE AGAIN THEY 3931 02:19:56,333 --> 02:19:58,301 WERE ASSOCIATED WITH MORE 3932 02:19:58,301 --> 02:19:59,536 INTENSE SELF TRANSCENDENCE 3933 02:19:59,536 --> 02:20:00,470 EXPERIENCES AND MEDIATED THE 3934 02:20:00,470 --> 02:20:01,938 EFFECT OF MORE ON REDUCING 3935 02:20:01,938 --> 02:20:03,273 OPIOID MISUSE THROUGH A 3936 02:20:03,273 --> 02:20:05,142 NINE-MONTH FOLLOW-UP POINT. 3937 02:20:05,142 --> 02:20:07,210 SO REPLICATING THESE RESULTS 3938 02:20:07,210 --> 02:20:08,578 ACROSS TWO RANDOMIZED CONTROL 3939 02:20:08,578 --> 02:20:10,247 TRIALS WITH TWO INDEPENDENT 3940 02:20:10,247 --> 02:20:11,314 SAMPLES SUGGESTS THAT WE MAY 3941 02:20:11,314 --> 02:20:12,716 HAVE INDEED FOUND A KEY 3942 02:20:12,716 --> 02:20:14,951 MECHANISM BY WHICH MINDFULNESS 3943 02:20:14,951 --> 02:20:20,524 REDUCES ADDICTIVE BEHAVIOR. 3944 02:20:20,524 --> 02:20:22,092 SPECULATIVELY, MINDFULNESS 3945 02:20:22,092 --> 02:20:24,194 INDUCED SELF TRANSCENDENCE MAY 3946 02:20:24,194 --> 02:20:26,329 PROMOTE A POTENT FORM OF 3947 02:20:26,329 --> 02:20:27,798 STIMULUS INDEPENDENT HAPPINESS. 3948 02:20:27,798 --> 02:20:29,666 LINKED WITH INCREASED THETA 3949 02:20:29,666 --> 02:20:31,334 OSCILLATIONS IN THE MEDIAL 3950 02:20:31,334 --> 02:20:33,437 PREFRONTAL CORTEX AND INCREASED 3951 02:20:33,437 --> 02:20:35,739 INTEGRATION BETWEEN TASK 3952 02:20:35,739 --> 02:20:37,107 POSITIVE BRAIN NETWORKS INVOLVES 3953 02:20:37,107 --> 02:20:39,076 IN SENSORY PROCESSING WITH TASK 3954 02:20:39,076 --> 02:20:41,078 NEGATIVE BRAIN NETWORKS INVOLVED 3955 02:20:41,078 --> 02:20:43,313 IN SELF REFERENTIAL PROCESSING. 3956 02:20:43,313 --> 02:20:43,780 MODULATING FUNCTIONAL 3957 02:20:43,780 --> 02:20:45,015 CONNECTIVITY PATTERNS THROUGH 3958 02:20:45,015 --> 02:20:48,318 SELF TRANSCENDENCE MAY RESET A 3959 02:20:48,318 --> 02:20:50,153 DEFAULT FUNCTION IN CHRONIC PAIN 3960 02:20:50,153 --> 02:20:51,621 AND ADDICTION, AND FACILITATE 3961 02:20:51,621 --> 02:20:53,724 THE RESTRUCTURING OF REWARD 3962 02:20:53,724 --> 02:20:55,258 PROCESSING IN CORTICOSTRIE A 3963 02:20:55,258 --> 02:21:02,399 TALL CIRCUITRY IN A ROLE TO EE O 3964 02:21:02,399 --> 02:21:03,200 ADDICTIVE BEHAVIOR. 3965 02:21:03,200 --> 02:21:04,935 THESE DATA ALSO CONVERGE WITH 3966 02:21:04,935 --> 02:21:07,137 ANCIENT WISDOM TEACHINGS. 3967 02:21:07,137 --> 02:21:08,939 TAKE THIS TEACHING FROM THE 3968 02:21:08,939 --> 02:21:09,606 SHIVA SUE TRA. 3969 02:21:09,606 --> 02:21:11,308 WHEN THE YOGI IS ESTABLISHED IN 3970 02:21:11,308 --> 02:21:13,043 PURE AWARENESS, HIS CRAVING IS 3971 02:21:13,043 --> 02:21:13,343 DESTROYED. 3972 02:21:13,343 --> 02:21:15,746 THUS HE SAVORS HIS OWN 3973 02:21:15,746 --> 02:21:17,714 INHERENTLY BLISSFUL NATURE, 3974 02:21:17,714 --> 02:21:20,784 WHICH ILLUMINS ITSELF WITH THE 3975 02:21:20,784 --> 02:21:22,619 RAYS OF ITS CONSCIOUSNESS, JUST 3976 02:21:22,619 --> 02:21:25,055 AT THE VERY MOMENT, THE YOGI 3977 02:21:25,055 --> 02:21:26,189 ABANDONS HIS CRAVING. 3978 02:21:26,189 --> 02:21:28,358 OR THIS QUOTE, IF BY GIVING UP A 3979 02:21:28,358 --> 02:21:29,092 LESSER HAPPINESS, A GREATER 3980 02:21:29,092 --> 02:21:30,527 HAPPINESS COULD BE FOUND. 3981 02:21:30,527 --> 02:21:31,962 A WISE PERSON WOULD RENOUNCE THE 3982 02:21:31,962 --> 02:21:33,230 LESSER FOR THE SAKE OF THE 3983 02:21:33,230 --> 02:21:38,969 GREATER. 3984 02:21:38,969 --> 02:21:40,637 BUT THESE DATA ALSO POINT 3985 02:21:40,637 --> 02:21:42,038 TOWARDS THE FUTURE AND THE 3986 02:21:42,038 --> 02:21:44,040 FUTURE OF NEUROSCIENCE AND I'M 3987 02:21:44,040 --> 02:21:45,942 QUITE INTERESTED IN COMBINING 3988 02:21:45,942 --> 02:21:50,280 MORE WITH OTHER INCLUDING 3989 02:21:50,280 --> 02:21:50,614 NEUROFEEDBACK. 3990 02:21:50,614 --> 02:21:52,282 SO MY COLLEAGUE AND I RECENTLY 3991 02:21:52,282 --> 02:21:54,417 COMPLETED A PILOT RANDOMIZED 3992 02:21:54,417 --> 02:21:57,521 CONTROL TRIAL OF MORE PLUS 3993 02:21:57,521 --> 02:21:58,355 NEUROFEEDBACK DURING SAVORING. 3994 02:21:58,355 --> 02:22:01,892 IN THIS STUDY WE USE FNIRS TO 3995 02:22:01,892 --> 02:22:04,294 PROVIDE REALTIME READOUT OF OFC 3996 02:22:04,294 --> 02:22:05,495 ACTIVITY WHILE THE PATIENT 3997 02:22:05,495 --> 02:22:07,030 SAVORS A ROSE. 3998 02:22:07,030 --> 02:22:08,598 AND WE'RE COMPARING THIS 3999 02:22:08,598 --> 02:22:11,234 CONDITION TO THE STANDARD MORE 4000 02:22:11,234 --> 02:22:13,436 THERAPY AS WELL AS SUPPORTIVE 4001 02:22:13,436 --> 02:22:14,237 GROUP PSYCH COTHERAPY CONTROL 4002 02:22:14,237 --> 02:22:14,738 CONDITION. 4003 02:22:14,738 --> 02:22:18,809 SO IN THE PROTOCOL, TRIALS BEGIN 4004 02:22:18,809 --> 02:22:21,344 WITH A REST PERIOD, THEN WHEN 4005 02:22:21,344 --> 02:22:22,779 THE INSTRUCTION TO SAVOR APPEARS 4006 02:22:22,779 --> 02:22:24,548 ON THE SCREEN AND I PICK UP THE 4007 02:22:24,548 --> 02:22:25,749 ROSE, YOU SHOULD HEAR AN 4008 02:22:25,749 --> 02:22:28,084 AUDITORY TONE THAT BECOMES 4009 02:22:28,084 --> 02:22:32,789 LOUDER WHEN THE ACTIVITY IN MY 4010 02:22:32,789 --> 02:22:37,494 OFC INCREASES. 4011 02:22:37,494 --> 02:22:39,963 YOU CAN SEE THE RED DOT ON THE 4012 02:22:39,963 --> 02:22:41,798 LAPTOP INDICATING LOCATION OF 4013 02:22:41,798 --> 02:22:42,599 BRAIN ACTIVATION. 4014 02:22:42,599 --> 02:22:43,600 MY FAVORITE PART OF THIS IS WHAT 4015 02:22:43,600 --> 02:22:44,701 HAPPENS WHEN THE TRIAL ENDS AND 4016 02:22:44,701 --> 02:22:45,936 I PUT DOWN THE ROSE. 4017 02:22:45,936 --> 02:22:56,213 SO CHECK IT OUT. 4018 02:23:01,251 --> 02:23:02,152 LOOK AT THE COMPUTER SCREEN. 4019 02:23:02,152 --> 02:23:04,354 >> THAT'S CRAZY. 4020 02:23:04,354 --> 02:23:06,189 YOU HAVE LIKE A REALLY STRONG 4021 02:23:06,189 --> 02:23:08,758 ACTIVATION OF THE RIGHT 4022 02:23:08,758 --> 02:23:10,961 ORBITOFRONTOCORTEX. 4023 02:23:10,961 --> 02:23:12,829 >> SO WE HAVE RESULTS FROM THIS 4024 02:23:12,829 --> 02:23:15,065 TRIAL, AND WE FIND A SIGNIFICANT 4025 02:23:15,065 --> 02:23:17,300 LINEAR INCREASE IN PREFRONTAL 4026 02:23:17,300 --> 02:23:18,468 CORTICAL ACTIVITY, AND 4027 02:23:18,468 --> 02:23:21,771 PARTICULARLY IN THE OFC, DURING 4028 02:23:21,771 --> 02:23:23,340 NATURAL REWARD PROCESSING ON THE 4029 02:23:23,340 --> 02:23:25,642 EMOTION REGULATION TASK. 4030 02:23:25,642 --> 02:23:27,878 AND GREATER INCREASES IN OFC 4031 02:23:27,878 --> 02:23:29,679 ACTIVITY DURING SAVORING ARE 4032 02:23:29,679 --> 02:23:31,481 CORRELATED WITH REDUCED OPIOID 4033 02:23:31,481 --> 02:23:33,783 MISUSE FOLLOWING TREATMENT. 4034 02:23:33,783 --> 02:23:35,719 WHICH IN MY VIEW PROVIDES STRONG 4035 02:23:35,719 --> 02:23:38,288 SUPPORT FOR THE RESTRUCTURING 4036 02:23:38,288 --> 02:23:40,290 REWARD HYPOTHESIS. 4037 02:23:40,290 --> 02:23:42,192 THE NOTION THAT INCREASING 4038 02:23:42,192 --> 02:23:43,894 SENSITIZATION TO NATURAL HEALTHY 4039 02:23:43,894 --> 02:23:46,096 PLEASURE, JOY, MEANING AND 4040 02:23:46,096 --> 02:23:47,230 TRANSCENDENCE WILL COME TO 4041 02:23:47,230 --> 02:23:48,932 OUTWEIGH THE PULL OF 4042 02:23:48,932 --> 02:23:51,201 DRUG-RELATED REWARD AND, 4043 02:23:51,201 --> 02:23:52,402 THEREBY, REDUCE ADDICTIVE 4044 02:23:52,402 --> 02:23:52,869 BEHAVIOR. 4045 02:23:52,869 --> 02:23:54,404 SO IN CONCLUSION, DISEASES OF 4046 02:23:54,404 --> 02:23:56,506 DESPAIR INCLUDING THE OPIOID 4047 02:23:56,506 --> 02:23:59,209 CRISIS BUT ALSO CHRONIC PAIN, 4048 02:23:59,209 --> 02:24:00,977 DEPRESSION, PTSD, MAY BE DRIVEN 4049 02:24:00,977 --> 02:24:04,247 BY HEDONIC DYSREGULATION AND 4050 02:24:04,247 --> 02:24:06,116 MALADAPTIVE SELF REFERENTIAL 4051 02:24:06,116 --> 02:24:06,449 PROCESSES. 4052 02:24:06,449 --> 02:24:08,518 MORE IS AN EVIDENCE-BASED 4053 02:24:08,518 --> 02:24:09,619 TREATMENT FOR CHRONIC PAIN AND 4054 02:24:09,619 --> 02:24:13,189 ADDICTION AS DEMONSTRATED BY 12 4055 02:24:13,189 --> 02:24:14,524 RANDOMIZED CONTROL TRIALS 4056 02:24:14,524 --> 02:24:15,292 INVOLVING MORE THAN 1300 4057 02:24:15,292 --> 02:24:16,126 PATIENTS. 4058 02:24:16,126 --> 02:24:17,027 EMOTIONAL WELL-BEING 4059 02:24:17,027 --> 02:24:20,063 INTERVENTIONS FOR OTHER HEALTH 4060 02:24:20,063 --> 02:24:27,237 CONDITIONS MIGHT ALSO INTEGRATE 4061 02:24:27,237 --> 02:24:28,872 SEQUENCES OF MINDFULNESS, 4062 02:24:28,872 --> 02:24:31,308 REAPPRAISAL AND SAVORING TO 4063 02:24:31,308 --> 02:24:33,143 PROMOTE EMOTION REGULATION WITH 4064 02:24:33,143 --> 02:24:35,111 TECHNIQUES TO CULTIVATE SELF 4065 02:24:35,111 --> 02:24:36,413 TRANS 16 DENT MEANING 4066 02:24:36,413 --> 02:24:37,814 INDEPENDENT OF STIMULUS DRIVEN 4067 02:24:37,814 --> 02:24:38,348 PLEASURE. 4068 02:24:38,348 --> 02:24:39,716 ULTIMATELY TEACHING PEOPLE TO 4069 02:24:39,716 --> 02:24:41,551 TAKE IN THE GOOD AND MINDFULLY 4070 02:24:41,551 --> 02:24:43,119 SAVER NATURAL, HEALTHY PLEASURE 4071 02:24:43,119 --> 02:24:44,754 MAY PROVIDE THE LEARNING SIGNAL 4072 02:24:44,754 --> 02:24:48,224 NEEDED TO RESTORE ADAPTIVE 4073 02:24:48,224 --> 02:24:50,126 HEDONIC REGULATION ACROSS A WIDE 4074 02:24:50,126 --> 02:24:51,962 RANGE OF HEALTH CONDITIONS. 4075 02:24:51,962 --> 02:24:56,633 SO I WANT TO THANK YOU AND THE 4076 02:24:56,633 --> 02:25:00,036 FUNDERS FOR THIS WORK. 4077 02:25:00,036 --> 02:25:01,471 >> THANK YOU SO MUCH, 4078 02:25:01,471 --> 02:25:02,339 DR. GARLAND, FOR ALL THAT GREAT 4079 02:25:02,339 --> 02:25:03,773 WORK AND PRESENTATION. 4080 02:25:03,773 --> 02:25:05,008 WHILE WE'RE WAITING FOR 4081 02:25:05,008 --> 02:25:06,009 QUESTIONS TO COME IN FROM THE 4082 02:25:06,009 --> 02:25:10,046 NIH VIDEOCAST FORM, AS MANY OF 4083 02:25:10,046 --> 02:25:11,548 YOU MAY HAVE NOT BEEN AS 4084 02:25:11,548 --> 02:25:12,882 FAMILIAR WITH DR. GARLAND'S 4085 02:25:12,882 --> 02:25:14,117 WORK, I WANT TO INVITE PEOPLE IN 4086 02:25:14,117 --> 02:25:16,286 THE ROOM WITH ME TO USE THEIR 4087 02:25:16,286 --> 02:25:17,654 MICROPHONES TO SEE IF THEY HAVE 4088 02:25:17,654 --> 02:25:18,722 ANY QUESTIONS FOR DR. GARLAND. 4089 02:25:18,722 --> 02:25:20,490 I SEE DR. RICHIE DAVIDSON'S HAND 4090 02:25:20,490 --> 02:25:21,691 IS UP SO PLEASE USE YOUR 4091 02:25:21,691 --> 02:25:22,192 MICROPHONE. 4092 02:25:22,192 --> 02:25:22,459 THANK YOU. 4093 02:25:22,459 --> 02:25:23,059 >> THANK YOU. 4094 02:25:23,059 --> 02:25:24,127 WONDERFUL TALK, ERIC. 4095 02:25:24,127 --> 02:25:26,096 IT'S GREAT TO SEE ALL THIS. 4096 02:25:26,096 --> 02:25:28,765 I HAVE A QUESTION AND A COMMENT. 4097 02:25:28,765 --> 02:25:31,234 I WANT TO ASK YOU AND PUSH A 4098 02:25:31,234 --> 02:25:34,704 LITTLE ON YOUR NOTION OF SELF 4099 02:25:34,704 --> 02:25:41,077 TRANSCENDENCE AND YOU MADE AN AN 4100 02:25:41,077 --> 02:25:43,179 ELUSION TO A MUSIC FESTIVAL 4101 02:25:43,179 --> 02:25:45,015 WHERE PEOPLE ARE EXPERIENCING 4102 02:25:45,015 --> 02:25:49,452 THESE STATES OF BLISS AND THEY 4103 02:25:49,452 --> 02:25:51,788 ARE LOSING THEIR SELF-AWARENESS 4104 02:25:51,788 --> 02:25:53,556 IN SOME WAY. 4105 02:25:53,556 --> 02:25:57,394 AND I JUST WANT TO ASK ABOUT 4106 02:25:57,394 --> 02:26:00,897 WHETHER YOU VIEW THESE AS 4107 02:26:00,897 --> 02:26:09,939 MONOLITHIC STATES OF RECEDING 4108 02:26:09,939 --> 02:26:11,241 SELF, AND SPECIFICALLY, AND YOU 4109 02:26:11,241 --> 02:26:16,279 TALKED ABOUT FLOW AS IF IT WERE 4110 02:26:16,279 --> 02:26:17,213 A SINGLE ENTITY, AND IN 4111 02:26:17,213 --> 02:26:19,015 PARTICULAR, I WANT TO JUST PUSH 4112 02:26:19,015 --> 02:26:24,020 BACK AND SAY WE HAVE MADE A VERY 4113 02:26:24,020 --> 02:26:24,687 IMPORTANT DISTINCTION BETWEEN 4114 02:26:24,687 --> 02:26:27,424 STATES OF FLOW THAT OCCUR WITH 4115 02:26:27,424 --> 02:26:32,495 AND WITHOUT META AWARENESS. 4116 02:26:32,495 --> 02:26:34,731 FLOW CAN OCCUR WITH OR WITHOUT 4117 02:26:34,731 --> 02:26:35,465 META AWARENESS, AND IF THESE 4118 02:26:35,465 --> 02:26:36,666 STATES OF FLOW WERE SO GREAT FOR 4119 02:26:36,666 --> 02:26:40,136 US AND REALLY THEMSELVES 4120 02:26:40,136 --> 02:26:42,038 PROMOTED WELL-BEING, THEN PEOPLE 4121 02:26:42,038 --> 02:26:43,473 WHO GO TO THESE CONCERTS SHOULD 4122 02:26:43,473 --> 02:26:46,676 ALL HAVE EXTREMELY POSITIVE 4123 02:26:46,676 --> 02:26:48,745 PSYCHOLOGICAL HEALTH, AND I 4124 02:26:48,745 --> 02:26:49,813 DON'T THINK COMMON OBSERVATION 4125 02:26:49,813 --> 02:26:51,648 SUPPORTS THAT. 4126 02:26:51,648 --> 02:26:53,349 AND SO I'M JUST WONDERING WHAT 4127 02:26:53,349 --> 02:26:56,152 YOUR THOUGHTS ARE ABOUT THAT. 4128 02:26:56,152 --> 02:26:56,853 >> GREAT QUESTION. 4129 02:26:56,853 --> 02:26:59,355 AND NO, I DON'T BELIEVE THIS IS 4130 02:26:59,355 --> 02:27:01,858 A MONOLITHIC SINGULAR STATE OR 4131 02:27:01,858 --> 02:27:02,092 ENTITY. 4132 02:27:02,092 --> 02:27:04,994 IN FACT, I VIEW SELF 4133 02:27:04,994 --> 02:27:06,196 TRANSCENDENCE LIKE MOST THINGS 4134 02:27:06,196 --> 02:27:11,334 AS ECK SITTING ECK SIT CYSTING O 4135 02:27:11,334 --> 02:27:14,070 TRANSCENDENCE AS ALL TO FULL 4136 02:27:14,070 --> 02:27:14,604 SELF TRANSCENDENCE. 4137 02:27:14,604 --> 02:27:16,706 I THINK THERE ARE VERY FINE 4138 02:27:16,706 --> 02:27:18,074 GRADE SCH GRADATIONS ACROSS -- 4139 02:27:18,074 --> 02:27:20,176 >> YOU CAN BE FULLY SELF 4140 02:27:20,176 --> 02:27:21,644 TRANSCENDENT WITH OR WITHOUT 4141 02:27:21,644 --> 02:27:22,011 META AWARENESS. 4142 02:27:22,011 --> 02:27:24,347 >> YEAH, I HEAR YOU, AND THAT 4143 02:27:24,347 --> 02:27:28,618 MAY HAVE QUITE DIFFERENT 4144 02:27:28,618 --> 02:27:29,853 PSYCHOPHYSIOLOGICAL PROFILES AND 4145 02:27:29,853 --> 02:27:31,054 HEALTH CONSEQUENCES, TRUE. 4146 02:27:31,054 --> 02:27:32,388 AND I DON'T THINK WE KNOW ENOUGH 4147 02:27:32,388 --> 02:27:34,424 ABOUT EITHER ONE OF THOSE 4148 02:27:34,424 --> 02:27:37,360 SCIENTIFICALLY TO BE ABLE TO 4149 02:27:37,360 --> 02:27:39,062 DISCRIMINATE WHAT FOR EXAMPLE A 4150 02:27:39,062 --> 02:27:41,064 FULL ABSORPTION STATE WHERE 4151 02:27:41,064 --> 02:27:44,501 THERE MAY NOT BE NO META 4152 02:27:44,501 --> 02:27:45,802 AWARENESS AT ALL VERSUS A STATE 4153 02:27:45,802 --> 02:27:46,870 THAT MAY PRECEDE THAT WHERE 4154 02:27:46,870 --> 02:27:48,605 THERE'S A HIGH LEVEL OF META 4155 02:27:48,605 --> 02:27:49,772 AWARENESS. 4156 02:27:49,772 --> 02:27:55,745 AND ONE MAY FEED INTO THE OTHER. 4157 02:27:55,745 --> 02:27:58,214 THANK YOU. 4158 02:27:58,214 --> 02:28:02,085 >> DR. JEAN SIMMONS? 4159 02:28:02,085 --> 02:28:03,353 >> THANKS, THAT WAS AMAZING. 4160 02:28:03,353 --> 02:28:07,023 I HAVE TWO QUESTIONS. 4161 02:28:07,023 --> 02:28:10,994 ONE IS ABOUT JUST IN THE CONTEXT 4162 02:28:10,994 --> 02:28:12,795 OF OPIATES AND OTHER DRUGS THAT 4163 02:28:12,795 --> 02:28:14,864 LEAD TO PHYSIOLOGICAL TOLERANCE 4164 02:28:14,864 --> 02:28:18,735 AND DEPENDENCE, HOW DO YOU 4165 02:28:18,735 --> 02:28:20,370 DEPLOY MORE IN THAT CONTEXT AND 4166 02:28:20,370 --> 02:28:23,039 HOW DOES THE PSYCHOLOGICAL 4167 02:28:23,039 --> 02:28:27,277 THEORY PUT FORWARD REALLY TO THE 4168 02:28:27,277 --> 02:28:29,445 PHYSIOLOGICAL DEPENDENCE 4169 02:28:29,445 --> 02:28:29,712 PROCESSES? 4170 02:28:29,712 --> 02:28:30,947 >> I THINK I MISSED THE FIRST 4171 02:28:30,947 --> 02:28:33,216 PART OF THAT. 4172 02:28:33,216 --> 02:28:35,285 SO -- IN WHICH POPULATIONS? 4173 02:28:35,285 --> 02:28:37,654 >> OH, OPIATES OR ANY DRUGS THAT 4174 02:28:37,654 --> 02:28:39,022 CAUSE PHYSIOLOGICAL DEPENDENCE. 4175 02:28:39,022 --> 02:28:42,759 >> HOW DO YOU DEPLOY IN THAT 4176 02:28:42,759 --> 02:28:42,992 CONTEXT? 4177 02:28:42,992 --> 02:28:44,260 >> DO THEY HAVE TO DETOX 4178 02:28:44,260 --> 02:28:45,228 BEFORE -- 4179 02:28:45,228 --> 02:28:46,996 >> NO, ABSOLUTELY NOT. 4180 02:28:46,996 --> 02:28:49,032 SO IN MOST OF THE STUDIES, WE'VE 4181 02:28:49,032 --> 02:28:50,466 BEEN STUDYING MORE WITH PEOPLE 4182 02:28:50,466 --> 02:28:52,702 WITH PAIN WHO HAVE A CURRENT 4183 02:28:52,702 --> 02:28:53,703 OPIOID PRESCRIPTION AND MANY OF 4184 02:28:53,703 --> 02:28:56,072 WHOM ARE TAKING HIGH DOSES OF 4185 02:28:56,072 --> 02:28:58,208 OPIOIDS AT THE BEGINNING OF THE 4186 02:28:58,208 --> 02:29:00,843 STUDY. 4187 02:29:00,843 --> 02:29:01,978 THAT'S PART OF THE INTENTION TO 4188 02:29:01,978 --> 02:29:03,446 HELP THEM REDUCE THEIR OPIOID 4189 02:29:03,446 --> 02:29:04,447 USE OR DOSE. 4190 02:29:04,447 --> 02:29:06,316 WE ALSO HAVE A DIFFERENT BODY OF 4191 02:29:06,316 --> 02:29:08,218 NIH NUNDED RESEARCH TO STUDY 4192 02:29:08,218 --> 02:29:09,619 MORE FOR PATIENTS WHO ARE NO 4193 02:29:09,619 --> 02:29:13,122 LONGER USING OPIOIDS AND ARE NOW 4194 02:29:13,122 --> 02:29:15,425 ON MEDICATIONS FOR OPIOID USE 4195 02:29:15,425 --> 02:29:16,025 DISORDER LIKE METHADONE, AND 4196 02:29:16,025 --> 02:29:17,660 THAT LINE OF WORK WHICH WAS 4197 02:29:17,660 --> 02:29:21,664 FUNDED BY NCCIH HAS YIELDED VERY 4198 02:29:21,664 --> 02:29:23,266 COMPELLING RESULTS SHOWING THAT 4199 02:29:23,266 --> 02:29:24,834 MORE IMPROVES ADDICTION 4200 02:29:24,834 --> 02:29:25,935 TREATMENT OUTCOMES THAT ADDING 4201 02:29:25,935 --> 02:29:27,570 MORE TO STANDARD ADDICTION 4202 02:29:27,570 --> 02:29:28,671 TREATMENT RESULTS IN 4203 02:29:28,671 --> 02:29:30,039 SIGNIFICANTLY FEWER DAYS OF DRUG 4204 02:29:30,039 --> 02:29:33,776 USE AND LESS RELAPSE. 4205 02:29:33,776 --> 02:29:34,711 GREATER ADHERENCE. 4206 02:29:34,711 --> 02:29:36,312 SO WE'VE STUDIED MORE IN BOTH 4207 02:29:36,312 --> 02:29:37,413 POPULATIONS AND THE PATIENT DOES 4208 02:29:37,413 --> 02:29:39,549 NOT NEED TO BE ABSTINENT FROM 4209 02:29:39,549 --> 02:29:41,017 DRUGS IN ORDER TO BENEFIT FROM 4210 02:29:41,017 --> 02:29:42,185 THIS THERAPY. 4211 02:29:42,185 --> 02:29:42,819 >> THANKS. 4212 02:29:42,819 --> 02:29:46,923 CAN I ASK ANOTHER QUESTION? 4213 02:29:46,923 --> 02:29:51,027 SO YOU PROPOSED A NUMBER OF 4214 02:29:51,027 --> 02:29:52,362 CAUSAL MECHANISMS THAT YOU 4215 02:29:52,362 --> 02:29:53,963 TESTED VERY ELEGANTLY IN LOTS OF 4216 02:29:53,963 --> 02:29:54,864 DIFFERENT WAYS. 4217 02:29:54,864 --> 02:29:59,202 SO THE NEUROBIOLOGICAL DATA ARE 4218 02:29:59,202 --> 02:30:00,236 REALLY FASCINATING BUT I'M 4219 02:30:00,236 --> 02:30:01,604 WONDERING AS YOU LOOK TO 4220 02:30:01,604 --> 02:30:03,740 DISSEMINATE THE TREATMENT, IF 4221 02:30:03,740 --> 02:30:05,942 YOU WANTED TO DEMONSTRATE THAT 4222 02:30:05,942 --> 02:30:08,344 THE TREATMENT BEING DELIVERED IN 4223 02:30:08,344 --> 02:30:11,381 SOME NEW LOCATION IN ALABAMA, 4224 02:30:11,381 --> 02:30:13,516 SAY, WAS ACTUALLY ENGAGING ONE 4225 02:30:13,516 --> 02:30:15,218 OF THOSE MECHANISMS, YOU MIGHT 4226 02:30:15,218 --> 02:30:18,454 NOT WANT THAT MECHANISM TO BE 4227 02:30:18,454 --> 02:30:24,193 REQU --REQUIRE NEUROIMAGING. 4228 02:30:24,193 --> 02:30:24,761 >> RIGHT. 4229 02:30:24,761 --> 02:30:26,396 >> ARE THERE WAYS THAT YOU'VE 4230 02:30:26,396 --> 02:30:28,698 LOOKED AT DIFFERENT -- DIFFERENT 4231 02:30:28,698 --> 02:30:29,565 MEASURES OF DIFFERENT MECHANISMS 4232 02:30:29,565 --> 02:30:33,236 TO BE ABLE TO THINK ABOUT THAT 4233 02:30:33,236 --> 02:30:35,071 QUESTION OF IN THE CLINIC, HOW 4234 02:30:35,071 --> 02:30:38,007 WOULD YOU TEST WHETHER THE 4235 02:30:38,007 --> 02:30:40,910 THERAPY WAS BEING DELIVERED 4236 02:30:40,910 --> 02:30:42,812 CORRECTLY OR WITH FIDELITY TO 4237 02:30:42,812 --> 02:30:45,515 ENGAGE THE MECHANISM? 4238 02:30:45,515 --> 02:30:49,052 >> CERTAINLY WE HAVE -- ACTUALLY 4239 02:30:49,052 --> 02:30:50,320 THE STAGE WHERE THIS RESEARCH 4240 02:30:50,320 --> 02:30:52,221 PROGRAM HAS NOW ARRIVED TO IS 4241 02:30:52,221 --> 02:30:53,723 REALLY THE STAGE OF 4242 02:30:53,723 --> 02:30:56,459 DISSEMINATION, I BELIEVE, AFTER 4243 02:30:56,459 --> 02:30:57,593 DOING 15 YEARS OF CLINICAL 4244 02:30:57,593 --> 02:31:00,263 TRIALS OF THIS THERAPY. 4245 02:31:00,263 --> 02:31:02,131 DEMONSTRATING ITS EFFICACY. 4246 02:31:02,131 --> 02:31:04,701 SO DISSEMINATING THE THERAPY AND 4247 02:31:04,701 --> 02:31:05,835 MAINTAINING A HIGH LEVEL OF 4248 02:31:05,835 --> 02:31:07,437 FIDELITY IS INCREDIBLY 4249 02:31:07,437 --> 02:31:09,038 IMPORTANT, AND SO WE HAVE 4250 02:31:09,038 --> 02:31:10,073 VALIDATED FIDELITY MEASURES THAT 4251 02:31:10,073 --> 02:31:12,775 WE CAN USE WITH CLINICIANS TO 4252 02:31:12,775 --> 02:31:15,945 ENSURE THAT THEY'RE DELIVERING 4253 02:31:15,945 --> 02:31:17,880 THE TREATMENT WITH A HIGH DEGREE 4254 02:31:17,880 --> 02:31:22,285 OF COMPETENCE TO THE TREATMENT 4255 02:31:22,285 --> 02:31:22,518 MANUAL. 4256 02:31:22,518 --> 02:31:24,287 TO DO IT RIGHT, YOU HAVE TOO 4257 02:31:24,287 --> 02:31:25,621 ACTUALLY AUDIO-RECORD THE 4258 02:31:25,621 --> 02:31:26,322 TREATMENT SESSION AND THEN 4259 02:31:26,322 --> 02:31:29,425 OBSERVE THE THERAPIST, HOW 4260 02:31:29,425 --> 02:31:30,393 THEY'RE INTERACTING AND SCORE 4261 02:31:30,393 --> 02:31:31,794 THEM ON THESE VARIOUS METRICS, 4262 02:31:31,794 --> 02:31:33,429 BUT THAT DOES ENSURE QUALITY 4263 02:31:33,429 --> 02:31:34,230 CONTROL. 4264 02:31:34,230 --> 02:31:36,366 IN TERMS OF TRANSPORTABLE 4265 02:31:36,366 --> 02:31:39,669 MEASURES OF MECHANISM INTO THE 4266 02:31:39,669 --> 02:31:42,372 CLINIC, I AGREE WITH YOU, I 4267 02:31:42,372 --> 02:31:43,906 THINK NEUROIMAGING IS PROBABLY 4268 02:31:43,906 --> 02:31:46,175 NOT THAT ACCESSIBLE, BUT 4269 02:31:46,175 --> 02:31:47,977 MEASURES LIKE HEART RATE 4270 02:31:47,977 --> 02:31:49,011 VARIABILITY WHICH NOW CAN BE 4271 02:31:49,011 --> 02:31:50,680 MEASURED WITH SIMPLE 4272 02:31:50,680 --> 02:31:51,414 COMMERCIALLY AVAILABLE 4273 02:31:51,414 --> 02:31:52,382 SMARTWATCHES COULD BE A GOOD WAY 4274 02:31:52,382 --> 02:32:00,390 OF GETTING AT IT. 4275 02:32:00,390 --> 02:32:02,191 >> FABULOUS AND VERY 4276 02:32:02,191 --> 02:32:02,592 THOUGHT-PROVOKING. 4277 02:32:02,592 --> 02:32:05,628 THANK YOU. 4278 02:32:05,628 --> 02:32:07,764 I'M THINKING OF THE AREA I WORK 4279 02:32:07,764 --> 02:32:09,932 IN, WHICH IS SUICIDE PREVENTION 4280 02:32:09,932 --> 02:32:11,634 SELF DESTRUCTIVE BEHAVIOR, WHICH 4281 02:32:11,634 --> 02:32:15,671 HAS MANY ADDICTIVE QUALITIES AND 4282 02:32:15,671 --> 02:32:16,739 CERTAIN CIRCUMSTANCES IN 4283 02:32:16,739 --> 02:32:17,907 POPULATIONS AND A NUMBER OF 4284 02:32:17,907 --> 02:32:18,841 DIFFERENT THERAPIES ARE BEING 4285 02:32:18,841 --> 02:32:25,181 DEVELOPED OR HAVE BEEN, SOME 4286 02:32:25,181 --> 02:32:26,649 LIKE MARSHAL AND -- DBT HAVE 4287 02:32:26,649 --> 02:32:27,750 SOME SIMILAR CHARACTERISTICS AS 4288 02:32:27,750 --> 02:32:29,318 I UNDERSTAND IT, OTHERS LESS SO. 4289 02:32:29,318 --> 02:32:31,053 I'M WONDERING ABOUT WHETHER 4290 02:32:31,053 --> 02:32:32,722 THERE ARE -- WHETHER YOUR WORK 4291 02:32:32,722 --> 02:32:35,224 SUGGESTS THAT THERE ARE 4292 02:32:35,224 --> 02:32:36,959 POTENTIAL SIGNIFICANT ADVERSE 4293 02:32:36,959 --> 02:32:40,096 CONSEQUENCES TO ADDRESSING THE 4294 02:32:40,096 --> 02:32:42,932 ADDICTION OR SUICIDAL IDEATION 4295 02:32:42,932 --> 02:32:43,399 BEHAVIOR. 4296 02:32:43,399 --> 02:32:46,068 FOR EXAMPLE, SPECIFICALLY 4297 02:32:46,068 --> 02:32:49,305 WITHOUT HAVING THIS OTHER ASPECT 4298 02:32:49,305 --> 02:32:51,841 TO IT, IS IT POSSIBLE THAT WE 4299 02:32:51,841 --> 02:32:56,379 COULD BE REINFORCING THE 4300 02:32:56,379 --> 02:32:58,047 IDENTITY BY FOCUSING ON THAT AS 4301 02:32:58,047 --> 02:33:00,416 A THERAPEUTIC TARGET RATHER THAN 4302 02:33:00,416 --> 02:33:01,417 SOMETHING ELSE? 4303 02:33:01,417 --> 02:33:03,719 >> THAT'S INTERESTING. 4304 02:33:03,719 --> 02:33:06,155 SO YOU'RE SPEAKING TO ADVERSE 4305 02:33:06,155 --> 02:33:07,623 CONSEQUENCES IN TERMS OF 4306 02:33:07,623 --> 02:33:09,592 STANDARD OF CARE FOR THESE 4307 02:33:09,592 --> 02:33:09,892 CONDITIONS? 4308 02:33:09,892 --> 02:33:11,027 >> YES, YES. 4309 02:33:11,027 --> 02:33:13,463 OR -- I MEAN, THERE ARE, YOU 4310 02:33:13,463 --> 02:33:15,097 KNOW, COLLABORATIVE ASSESSMENT 4311 02:33:15,097 --> 02:33:18,167 MANAGEMENT OF SUICIDE -- 4312 02:33:18,167 --> 02:33:20,002 EVIDENCE-BASED TREATMENT, 4313 02:33:20,002 --> 02:33:21,871 SUICIDAL BEHAVIOR AND COGNITIVE 4314 02:33:21,871 --> 02:33:23,573 BEHAVIORAL THERAPY FOR SUICIDAL 4315 02:33:23,573 --> 02:33:24,574 BEHAVIOR ALSO, BUT AS I 4316 02:33:24,574 --> 02:33:25,942 UNDERSTAND IT, THEY DON'T 4317 02:33:25,942 --> 02:33:26,976 INCORPORATE ASPECTS THAT YOU ARE 4318 02:33:26,976 --> 02:33:29,245 TOUCHING ON HERE. 4319 02:33:29,245 --> 02:33:30,546 AND ABSENT THAT, ARE THEY 4320 02:33:30,546 --> 02:33:31,614 POTENTIALLY IN SOME PEOPLE 4321 02:33:31,614 --> 02:33:32,748 MAKING THINGS WORSE? 4322 02:33:32,748 --> 02:33:35,751 >> MY REFLECTION ON YOUR 4323 02:33:35,751 --> 02:33:38,054 COMMENT, I THINK RELATES TO IN 4324 02:33:38,054 --> 02:33:40,490 MANY WAYS WHY WE'RE HERE IN THIS 4325 02:33:40,490 --> 02:33:42,091 ROOM, PURSUING THE SCIENCE OF 4326 02:33:42,091 --> 02:33:43,659 EMOTIONAL WELL-BEING. 4327 02:33:43,659 --> 02:33:48,598 THAT FOCUSING ON DEFICITS AND 4328 02:33:48,598 --> 02:33:50,066 PATHOLOGY AND ATTEMPTING TO 4329 02:33:50,066 --> 02:33:52,168 REMOVE NEGATIVE SYMPTOMS, 4330 02:33:52,168 --> 02:33:53,803 REMOVING AND AMELIORATING A 4331 02:33:53,803 --> 02:33:55,071 NEGATIVE SYMPTOM IS NOT THE SAME 4332 02:33:55,071 --> 02:33:58,741 THING AS ENHANCING SHREW DOUGH 4333 02:33:58,741 --> 02:33:59,308 GENESIS. 4334 02:33:59,308 --> 02:34:00,776 OBVIOUSLY IT'S NECESSARY IN MANY 4335 02:34:00,776 --> 02:34:02,478 CASES TO TREAT THE SYMPTOM AND 4336 02:34:02,478 --> 02:34:06,949 RELIEVE THE NEGATIVE EMOTIONAL 4337 02:34:06,949 --> 02:34:07,583 SYMPTOM. 4338 02:34:07,583 --> 02:34:08,784 THE MERE ABSENCE DOESN'T MEAN 4339 02:34:08,784 --> 02:34:10,520 THE PRESENCE OF EMOTIONAL 4340 02:34:10,520 --> 02:34:12,188 WELL-BEING OR FLOURISHING, AND I 4341 02:34:12,188 --> 02:34:13,856 THINK IN THE CASE OF SOMEBODY 4342 02:34:13,856 --> 02:34:15,725 WHO'S SUICIDAL OR THE CASE OF 4343 02:34:15,725 --> 02:34:18,261 SOMEBODY WHO HAS A SEVERE 4344 02:34:18,261 --> 02:34:20,263 ADDICTION, AS I TRIED TO IMPLY 4345 02:34:20,263 --> 02:34:27,103 HERE, THERE'S REALLY A TERRIBLE 4346 02:34:27,103 --> 02:34:31,007 PROCESS THAT OCCURS IN THE SELF 4347 02:34:31,007 --> 02:34:32,642 REFERENTIAL DEFAULT MODE NATURE 4348 02:34:32,642 --> 02:34:35,177 OF ONE'S SENSE OF IDENTITY 4349 02:34:35,177 --> 02:34:37,280 BECOMES MEYERED IN THE SENSE OF 4350 02:34:37,280 --> 02:34:38,548 WORTHLESSNESS, HOPELESSNESS, 4351 02:34:38,548 --> 02:34:39,849 BEING FLAWED OR BROKEN IN SOME 4352 02:34:39,849 --> 02:34:41,183 SORT OF WAY. 4353 02:34:41,183 --> 02:34:44,687 AND SO TO HELP SOMEBODY TO TALL 4354 02:34:44,687 --> 02:34:47,957 INTO THIS ALTERNATIVE EXPERIENCE 4355 02:34:47,957 --> 02:34:49,926 OF THEMSELF AND CONNECTEDNESS 4356 02:34:49,926 --> 02:34:51,761 WITH THE UNIVERSE AS HEALTHY AND 4357 02:34:51,761 --> 02:34:54,797 VIBRANT AND RESILIENT AND FULL 4358 02:34:54,797 --> 02:34:57,400 OF MEANING OR TAPPED INTO THE 4359 02:34:57,400 --> 02:35:01,237 BASIC NATURE OF GOODNESS, COULD 4360 02:35:01,237 --> 02:35:02,405 BE HEALING IN A WHOLE DIFFERENT 4361 02:35:02,405 --> 02:35:03,839 WAY THAN THE TRADITIONAL 4362 02:35:03,839 --> 02:35:05,608 APPROACHES TO DEALING WITH THESE 4363 02:35:05,608 --> 02:35:08,177 MENTAL HEALTH PROBLEMS. 4364 02:35:08,177 --> 02:35:10,746 THAT'S MY REFLECTION ON YOUR 4365 02:35:10,746 --> 02:35:12,348 QUESTION. 4366 02:35:12,348 --> 02:35:13,549 >> WE'RE A LITTLE OVER SO I'M 4367 02:35:13,549 --> 02:35:15,017 GOING TO PRIORITIZE ONE QUESTION 4368 02:35:15,017 --> 02:35:17,253 FROM THE VIDEOCAST AUDIENCE 4369 02:35:17,253 --> 02:35:19,021 SINCE YOU'LL BE HERE TO SPEAK 4370 02:35:19,021 --> 02:35:21,190 WITH DR. GARLAND FOR THE REST OF 4371 02:35:21,190 --> 02:35:21,557 THE DAY. 4372 02:35:21,557 --> 02:35:23,292 ONE QUESTION FROM OUR VIDEOCAST 4373 02:35:23,292 --> 02:35:24,694 AUDIENCE, THIS INDIVIDUAL IS AN 4374 02:35:24,694 --> 02:35:27,129 OCCUPATIONAL THERAPIST AND HAS 4375 02:35:27,129 --> 02:35:28,531 UTILIZED MULTIPLE SENSES TO 4376 02:35:28,531 --> 02:35:31,100 SUPPORT BODY SYSTEMS AND SO 4377 02:35:31,100 --> 02:35:31,968 THEY'RE WONDERING ABOUT ADAPTING 4378 02:35:31,968 --> 02:35:33,269 AND MODIFYING THE ENVIRONMENT TO 4379 02:35:33,269 --> 02:35:35,671 HEIGHTEN THE POSITIVE IMPACT OF 4380 02:35:35,671 --> 02:35:37,340 MINDFULNESS AS BEING KEY FOR 4381 02:35:37,340 --> 02:35:39,875 NEURODIVERSE POPULATIONS AND 4382 02:35:39,875 --> 02:35:40,810 TRAUMA-INFORMED CARE. 4383 02:35:40,810 --> 02:35:41,877 SO THEY'RE WONDERING IF YOU'VE 4384 02:35:41,877 --> 02:35:43,145 COLLABORATED WITH OCCUPATIONAL 4385 02:35:43,145 --> 02:35:44,280 THERAPISTS TO BE MORE MIND FULL 4386 02:35:44,280 --> 02:35:46,182 OF THE NEURODIVERSE NEEDS 4387 02:35:46,182 --> 02:35:48,017 INCLUDING SENSORY DIFFERENCES IN 4388 02:35:48,017 --> 02:35:49,151 LEARNING STYLES AND IF NOT, ARE 4389 02:35:49,151 --> 02:35:50,686 YOU CONSIDERING COLLABORATING 4390 02:35:50,686 --> 02:35:52,288 WITH OTHER HEALTH PROFESSIONALS? 4391 02:35:52,288 --> 02:35:54,123 >> NO, I HAVEN'T DONE THAT, BUT 4392 02:35:54,123 --> 02:35:57,593 THAT'S A REALLY GOOD IDEA. 4393 02:35:57,593 --> 02:35:59,962 AND I THINK THE PRACTICE OF 4394 02:35:59,962 --> 02:36:01,297 SAVORING MAY BE SOMETHING THAT'S 4395 02:36:01,297 --> 02:36:03,232 MORE ACCESSIBLE TO PEOPLE WHO 4396 02:36:03,232 --> 02:36:05,001 DON'T LEARN IN TRADITIONAL WAYS, 4397 02:36:05,001 --> 02:36:06,268 BECAUSE IT REALLY IS A 4398 02:36:06,268 --> 02:36:09,739 SENSORY-BASED APPROACH TO USING 4399 02:36:09,739 --> 02:36:13,509 MINDFULNESS, AND FOR PEOPLE WHO 4400 02:36:13,509 --> 02:36:15,277 MAY HAVE DIFFICULTY WITH 4401 02:36:15,277 --> 02:36:16,312 INTEROCEPTION AND USING THE 4402 02:36:16,312 --> 02:36:18,314 BREATH, FOR EXAMPLE, AS A 4403 02:36:18,314 --> 02:36:20,583 TRADITIONAL FOCUS OF MINDFULNESS 4404 02:36:20,583 --> 02:36:26,389 PRACTICE, IN SAVORING, IT'S A 4405 02:36:26,389 --> 02:36:27,023 BEAUTIFUL EXTERNAL OBJECT SO IT 4406 02:36:27,023 --> 02:36:29,425 MAY BE EASIER TO FOCUS ATTENTION 4407 02:36:29,425 --> 02:36:30,393 ON THAN INTERNAL SENSORY 4408 02:36:30,393 --> 02:36:31,594 EXPERIENCE. 4409 02:36:31,594 --> 02:36:33,596 SO I THINK THAT'S A GOOD IDEA 4410 02:36:33,596 --> 02:36:35,197 THAT USING AN ENRICHED 4411 02:36:35,197 --> 02:36:37,133 ENVIRONMENT TO BECOME A TARGET 4412 02:36:37,133 --> 02:36:38,801 FOR MINDFULNESS PRACTICES MIGHT 4413 02:36:38,801 --> 02:36:39,902 MAKE IT MORE ACCESSIBLE TO 4414 02:36:39,902 --> 02:36:43,506 DIFFERENT POPULATIONS. 4415 02:36:43,506 --> 02:36:45,041 >> THANK YOU, DR. GARLAND. 4416 02:36:45,041 --> 02:36:50,012 [APPLAUSE] 4417 02:36:50,012 --> 02:36:51,480 >> WELL, THANK YOU, EVERYONE. 4418 02:36:51,480 --> 02:36:53,482 THAT CONCLUDES THE OPEN SESSION 4419 02:36:53,482 --> 02:36:56,085 OF THE 2024 ANNUAL EMOTIONAL 4420 02:36:56,085 --> 02:36:57,486 WELL-BEING INVESTIGATOR MEETING. 4421 02:36:57,486 --> 02:36:58,888 AGAIN, THANK YOU VERY MUCH, 4422 02:36:58,888 --> 02:37:01,557 DR. ERIC GARLAND, THE EMOTIONAL 4423 02:37:01,557 --> 02:37:04,026 WELL-BEING NETWORKS AND OUR NIH 4424 02:37:04,026 --> 02:37:04,727 INSTITUTE AND CENTER DIRECTORS 4425 02:37:04,727 --> 02:37:06,562 FOR THEIR PARTICIPATION IN THIS 4426 02:37:06,562 --> 02:37:07,730 WONDERFUL MEETING ON ADVANCING 4427 02:37:07,730 --> 02:37:09,498 THE SCIENCE OF EMOTIONAL 4428 02:37:09,498 --> 02:37:10,533 WELL-BEING AND OF COURSE A BIG 4429 02:37:10,533 --> 02:37:11,834 THANK YOU TO ALL OF YOU WHO 4430 02:37:11,834 --> 02:37:14,270 REGISTERED AND JOINED US BY 4431 02:37:14,270 --> 02:37:15,037 VIDEOCAST. 4432 02:37:15,037 --> 02:37:17,540 WE'RE REALLY APPRECIATIVE OF ALL 4433 02:37:17,540 --> 02:37:19,308 THE ENTHUSIASM WE SAW IN YOUR 4434 02:37:19,308 --> 02:37:20,409 REGISTRATION NUMBERS TO LEARN 4435 02:37:20,409 --> 02:37:21,444 MORE ABOUT EMOTIONAL WELL-BEING 4436 02:37:21,444 --> 02:37:23,646 AND WHAT NIH IS DOING TO SUPPORT 4437 02:37:23,646 --> 02:37:25,915 AND ADVANCE THE SCIENCE OF 4438 02:37:25,915 --> 02:37:26,582 EMOTIONAL WELL-BEING. 4439 02:37:26,582 --> 02:37:28,184 THIS WILL BE VIDEOCAST AND 4440 02:37:28,184 --> 02:37:29,785 ARCHIVED SO FEEL FREE TO 4441 02:37:29,785 --> 02:37:30,553 DISSEMINATE TO COLLEAGUES WHO 4442 02:37:30,553 --> 02:37:32,088 COULDN'T JOIN TODAY IN REALTIME 4443 02:37:32,088 --> 02:37:33,389 AND WE WILL ALSO BE ARCHIVING A 4444 02:37:33,389 --> 02:37:34,290 LOT OF THIS INFORMATION ON 4445 02:37:34,290 --> 02:37:34,757 VARIOUS WEBSITES. 4446 02:37:34,757 --> 02:37:36,358 SO AGAIN, A BIG ROUND OF 4447 02:37:36,358 --> 02:37:37,493 APPLAUSE, A BIG THANK YOU TO ALL 4448 02:37:37,493 --> 02:37:38,561 OF YOU HERE IN THE ROOM AND TO 4449 02:37:38,561 --> 02:37:40,362 THOSE OF YOU JOINING BY 4450 02:37:40,362 --> 02:37:41,097 VIDEOCAST, THANK YOU SO MUCH. 4451 02:37:41,097 --> 02:37:51,273 [APPLAUSE]