1
00:00:05,600 --> 00:00:10,400
I AM SAMIA NOURSI.

2
00:00:10,400 --> 00:00:15,160
EXECUTIVE SECRETARY OF THIS

3
00:00:15,160 --> 00:00:18,560
COMMITTEE AND ASSOCIATE DIRECTOR

4
00:00:18,560 --> 00:00:21,240
SM I WOULD LIKE TO CALL TO ORDER

5
00:00:21,240 --> 00:00:22,000
THE NIH ADVISE RECOMMITTEE ON

6
00:00:22,000 --> 00:00:23,800
RESEARCH ON WOMEN'S HEALTH.

7
00:00:23,800 --> 00:00:25,600
THIS MEETING IS OPEN TO THE

8
00:00:25,600 --> 00:00:29,920
PUBLIC VIA LIVE BROADCAST AND ON

9
00:00:29,920 --> 00:00:32,440
THE NIH VIDEO NETWORK, VIDEOCAST

10
00:00:32,440 --> 00:00:34,120
NETWORK, IT IS BEING RECORDED

11
00:00:34,120 --> 00:00:36,560
FOR OUR ARCHIVES AND FOR FUTURE

12
00:00:36,560 --> 00:00:38,840
ON DEMAND VIEWING BY THE PUBLIC.

13
00:00:38,840 --> 00:00:43,520
IF YOU ARE A MEMBER OF THE

14
00:00:43,520 --> 00:00:45,680
PUBLIC, PERTHE FEDERAL REGISTER

15
00:00:45,680 --> 00:00:47,120
NOTICE, YOU MAY SUBMIT YOUR

16
00:00:47,120 --> 00:00:50,000
QUESTIONS IN WRITING DIRECTLY TO

17
00:00:50,000 --> 00:00:59,920
ME AT SAMIA.NOURSI @NIH.GOV.

18
00:00:59,920 --> 00:01:03,640
THAT IS SAMIA.NOURSI @NIH.GOV.

19
00:01:03,640 --> 00:01:05,240
YOU WILL RECEIVE AN ANSWER FROM

20
00:01:05,240 --> 00:01:07,560
ME DIRECTLY.

21
00:01:07,560 --> 00:01:11,720
WE ARE JOINING REMOTELY EVENT

22
00:01:11,720 --> 00:01:13,360
PARTICIPANTS AND PRESENTER SAYS

23
00:01:13,360 --> 00:01:14,320
ARE PRESENTING THROUGH ZOOM.

24
00:01:14,320 --> 00:01:17,560
AS MEMBERS OF THE FEDERAL

25
00:01:17,560 --> 00:01:19,680
ADVISORY COMMITTEE YOU ARE

26
00:01:19,680 --> 00:01:21,640
SPECIAL GOVERNMENT EMPLOYEES, WE

27
00:01:21,640 --> 00:01:22,560
CALL USGEs.

28
00:01:22,560 --> 00:01:24,560
WHICH MEANS YOU ARE SUBJECT TO

29
00:01:24,560 --> 00:01:26,400
THE SAME ETHIC RULES THAT APPLY

30
00:01:26,400 --> 00:01:27,720
TO GOVERNMENT EMPLOYEES.

31
00:01:27,720 --> 00:01:31,600
THESE RULES ARE DESCRIBED IN THE

32
00:01:31,600 --> 00:01:33,600
PAMPHLET ENTITLED STANDARDS OF

33
00:01:33,600 --> 00:01:35,600
ETHICAL CONDUCT OF EMPLOYEES FOR

34
00:01:35,600 --> 00:01:36,040
THE EXECUTIVE BRANCH.

35
00:01:36,040 --> 00:01:37,520
YOU WILL RECEIVE THE COPY OF

36
00:01:37,520 --> 00:01:40,720
THIS DOCUMENT WHEN YOU WERE

37
00:01:40,720 --> 00:01:41,000
APPOINTED.

38
00:01:41,000 --> 00:01:42,280
AT EVERY MEETING WE LIKE TO

39
00:01:42,280 --> 00:01:43,720
REVIEW THE STEPS WE TAKE AND THE

40
00:01:43,720 --> 00:01:45,320
PROCESS WE FOLLOW TO IDENTIFY

41
00:01:45,320 --> 00:01:47,760
AND ARK ADDRESS ANY CONFLICTS

42
00:01:47,760 --> 00:01:50,920
BETWEEN YOU, YOUR PUBLIC, THE

43
00:01:50,920 --> 00:01:54,560
RESPONSIBILITY AND YOUR PRIVATE

44
00:01:54,560 --> 00:01:55,040
INTERESTS.

45
00:01:55,040 --> 00:01:56,520
AS YOU KNOW BEFORE EVERY

46
00:01:56,520 --> 00:01:57,800
MEETING, YOU PROVIDE US WITH A

47
00:01:57,800 --> 00:01:59,680
GREAT DEAL OF INFORMATION ABOUT

48
00:01:59,680 --> 00:02:04,200
YOUR PROFESSIONAL, PERSONAL AND

49
00:02:04,200 --> 00:02:04,600
FINANCIAL INTERESTS.

50
00:02:04,600 --> 00:02:06,200
WE USE THIS INFORMATION AS THE

51
00:02:06,200 --> 00:02:07,640
FOUNDATIONS FOR ASSESSING

52
00:02:07,640 --> 00:02:09,800
WHETHER YOU HAVE ANY REAL

53
00:02:09,800 --> 00:02:14,080
POTENTIAL OR APPARENT CONFLICTS

54
00:02:14,080 --> 00:02:15,480
OF INTEREST THAT COULD

55
00:02:15,480 --> 00:02:19,480
COMPROMISE YOUR ABILITY TO BE

56
00:02:19,480 --> 00:02:21,440
OBJECTIVE TO GIVE ADVICE DURING

57
00:02:21,440 --> 00:02:22,480
COMMITTEE MEETINGS.

58
00:02:22,480 --> 00:02:25,400
IF YOU THE NEED FOR INDIVIDUAL

59
00:02:25,400 --> 00:02:27,040
SERVICES ARE IN PLACE OF A

60
00:02:27,040 --> 00:02:29,720
POTENTIAL CONFLICTS OF INTEREST,

61
00:02:29,720 --> 00:02:31,320
WE HAVE IDENTIFIED WE WOULD

62
00:02:31,320 --> 00:02:36,240
ISSUE YOU A WAIVER OR RESCUE

63
00:02:36,240 --> 00:02:37,000
YOU--RECUSE YOU--EXCUSE ME--FROM

64
00:02:37,000 --> 00:02:38,480
A PARTICULAR PORTION OF MEETING.

65
00:02:38,480 --> 00:02:39,880
WE USUALLY WAVE CONFLICTS OF

66
00:02:39,880 --> 00:02:41,240
INTEREST FOR GENERAL MATTERS

67
00:02:41,240 --> 00:02:42,480
BECAUSE WE BELIEVE YOUR ABILITY

68
00:02:42,480 --> 00:02:45,800
TO BE OBJECTIVE WILL NOT BE

69
00:02:45,800 --> 00:02:47,280
AFFECTED BY YOUR FINANCIAL

70
00:02:47,280 --> 00:02:47,560
INTEREST.

71
00:02:47,560 --> 00:02:49,280
WE ALSO RELY A GREAT DEAL ON

72
00:02:49,280 --> 00:02:50,280
YOU.

73
00:02:50,280 --> 00:02:52,440
YOU NEED TO BE ATTENTIVE DURING

74
00:02:52,440 --> 00:02:55,120
MEETINGS TO THE POSSIBILITY THAT

75
00:02:55,120 --> 00:02:57,320
AN ISSUE COULD ARISE THAT COULD

76
00:02:57,320 --> 00:03:00,280
AFFECT OR APPEAR TO AFFECT YOUR

77
00:03:00,280 --> 00:03:01,440
FINANCIAL INTEREST WITH RESPECT

78
00:03:01,440 --> 00:03:03,120
TO A SPECIFIC PARTY OR MATTER.

79
00:03:03,120 --> 00:03:05,760
IF THIS HAPPENS, YOU WILL BE

80
00:03:05,760 --> 00:03:07,640
ASKED TO RECUSE YOURSELF FROM

81
00:03:07,640 --> 00:03:10,200
THAT PORTION OF THE MEETING.

82
00:03:10,200 --> 00:03:11,800
BEFORE INTRODUCTION, I WILL

83
00:03:11,800 --> 00:03:14,080
BRIEFLY REVIEW BEST PRACTICES

84
00:03:14,080 --> 00:03:16,080
FOR OUR ZOOM PARTICIPANTS.

85
00:03:16,080 --> 00:03:21,360
YOU KNOW THIS BUT JUST A

86
00:03:21,360 --> 00:03:22,760
REMINDER, PLEASE MUTE YOUR MIC

87
00:03:22,760 --> 00:03:24,880
IF YOU ARE NOT SPEAKING.

88
00:03:24,880 --> 00:03:26,480
WHEN SPEAKING STATE YOUR NAME

89
00:03:26,480 --> 00:03:28,480
BEFORE MAKING COMMENTS, MOTIONS

90
00:03:28,480 --> 00:03:28,920
OR RECOMMENDATIONS.

91
00:03:28,920 --> 00:03:33,920
TRY TO USE THE HEAD SET WITH MIC

92
00:03:33,920 --> 00:03:35,680
WHEN SPEAKING AND THAT WILL

93
00:03:35,680 --> 00:03:37,640
PROVIDE THE LEAST AMOUNT OF

94
00:03:37,640 --> 00:03:38,000
AUDIO FEEDBACK.

95
00:03:38,000 --> 00:03:39,960
TURN OFF YOUR VIDEO IF YOU'RE

96
00:03:39,960 --> 00:03:41,520
NOT SPEAKING TO PRESERVE

97
00:03:41,520 --> 00:03:42,000
INTERNET BAND WIDTH.

98
00:03:42,000 --> 00:03:44,360
IF YOU HAVE A QUESTION OR WOULD

99
00:03:44,360 --> 00:03:46,200
LIKE TO MACK A COMMENT, PLEASE

100
00:03:46,200 --> 00:03:47,760
UTILIZE THE CHAT FEATURE.

101
00:03:47,760 --> 00:03:49,160
THE ZOOM SHAT WILL BE KEPT AS

102
00:03:49,160 --> 00:03:50,600
PART OF THE OFFICIAL MEETING

103
00:03:50,600 --> 00:03:50,840
RECORD.

104
00:03:50,840 --> 00:03:55,480
WE WILL BE VOTING WITH THE ZOOM

105
00:03:55,480 --> 00:03:56,960
POLLING FUNCTION.

106
00:03:56,960 --> 00:03:58,760
DURING THE VOTE, MULTIPLE

107
00:03:58,760 --> 00:04:00,280
SELECTIONS WILL DISPLAY ON THE

108
00:04:00,280 --> 00:04:01,760
SCREEN, PLEASE SELECT YOUR

109
00:04:01,760 --> 00:04:02,520
RESPONSE AND CLICK SUBMIT.

110
00:04:02,520 --> 00:04:06,720
I WOULD LIKE TO WELCOME OUR

111
00:04:06,720 --> 00:04:08,640
NEWEST ACRWH MEMBERS, DR. STEVEN

112
00:04:08,640 --> 00:04:10,040
HIGGINS ISSUES PROFESSOR OF

113
00:04:10,040 --> 00:04:11,880
PSYCHOLOGY AND PSYCHIATRIST AND

114
00:04:11,880 --> 00:04:13,280
DREBLGHTOR OF VERMONT CENTER ON

115
00:04:13,280 --> 00:04:15,440
BEHAVIOR AND HEALTH AT THE

116
00:04:15,440 --> 00:04:21,080
UNIVERSITY OF VERMONT.

117
00:04:21,080 --> 00:04:22,120
DR. ANDRIEA JONES PROFESSOR AND

118
00:04:22,120 --> 00:04:23,840
EXECUTIVE DIRECTOR OF THE

119
00:04:23,840 --> 00:04:25,120
HORIZONS PROGRAM IN THE

120
00:04:25,120 --> 00:04:26,840
DEPARTMENT OF OBSTETRICS AND

121
00:04:26,840 --> 00:04:28,160
GYNECOLOGY AT THE UNIVERSITY OF

122
00:04:28,160 --> 00:04:33,440
NORTH CAROLINA AT CHAPEL HILL

123
00:04:33,440 --> 00:04:35,520
SCHOOL OF MEDICINE.

124
00:04:35,520 --> 00:04:41,320
DR. THELLIAL CELLS MA MIELENZ,

125
00:04:41,320 --> 00:04:44,920
PROFESSOR OF MEDICAL AT CO

126
00:04:44,920 --> 00:04:51,160
LUNLBIA UNIVERSITY. 

127
00:04:51,160 --> 00:04:54,320
DR. ALEXANDRA NOEL, UPON SCHOOL

128
00:04:54,320 --> 00:04:56,480
OF VETERINARY MEDICINE LOUISIANA

129
00:04:56,480 --> 00:05:03,800
STATE UNIVERSITY AND DR. PHILIS

130
00:05:03,800 --> 00:05:06,360
SHARPS, Ph.D., MSN, RN AT THE

131
00:05:06,360 --> 00:05:06,880
JOHNS HOPKINS UNIVERSITY.

132
00:05:06,880 --> 00:05:07,920
WE LOOK FORWARD TO WORKING

133
00:05:07,920 --> 00:05:09,880
CLOSELY WITH YOU IN THE COMING

134
00:05:09,880 --> 00:05:13,440
YEARS AND WELCOME EVERYONE.

135
00:05:13,440 --> 00:05:15,480
s AS I GO THROUGH THE ROSTER,

136
00:05:15,480 --> 00:05:17,560
WHEN YOU HEAR YOUR NAME PLEASE

137
00:05:17,560 --> 00:05:19,280
UNMUTE YOUR MIC AND INTRODUCE

138
00:05:19,280 --> 00:05:22,400
YOURSELF BY NAME AND WHAT

139
00:05:22,400 --> 00:05:28,680
INSTITUTION YOU REPRESENT.

140
00:05:28,680 --> 00:05:29,240
DR. ANDERSON?

141
00:05:29,240 --> 00:05:30,760
>>GOOD MORNING DR.
ANDERSON

142
00:05:30,760 --> 00:05:33,000
FROM THE FRED HUTCHISON CANCER

143
00:05:33,000 --> 00:05:38,240
RESEARCH CENTER NTHANK YOU

144
00:05:38,240 --> 00:05:38,680
DR. ANDERSON.

145
00:05:38,680 --> 00:05:39,280
>>DR. [INDISCERNIBLE]

146
00:05:39,280 --> 00:05:40,080
>>GOOD MORNING

147
00:05:40,080 --> 00:05:41,160
DR. [INDISCERNIBLE] FROM THE

148
00:05:41,160 --> 00:05:42,400
SOCIETY FOR WOMEN'S HEALTH

149
00:05:42,400 --> 00:05:43,720
RESEARCH.

150
00:05:43,720 --> 00:05:47,400
>>THANK YOU DOCTOR,

151
00:05:47,400 --> 00:05:47,760
DR. BRUGALL?

152
00:05:47,760 --> 00:05:49,840
>>THE DOCTOR HASN'T
JOINED US

153
00:05:49,840 --> 00:05:51,080
YET.

154
00:05:51,080 --> 00:05:53,640
>>THANK YOU SARAH.

155
00:05:53,640 --> 00:05:54,080
DR. HIGGINS.

156
00:05:54,080 --> 00:05:56,000
>>HI, STEVE HIGGINS FROM
THE

157
00:05:56,000 --> 00:05:57,560
UNIVERSITY OF VERMONT, GLAD TO

158
00:05:57,560 --> 00:06:00,280
BE WITH YOU.

159
00:06:00,280 --> 00:06:00,680
>>DR. HOLGREN?

160
00:06:00,680 --> 00:06:03,440
>>HI, EVERYBODY, SCOTT
HOLGREN,

161
00:06:03,440 --> 00:06:04,720
AT WASHINGTON UNIVERSITY IN

162
00:06:04,720 --> 00:06:05,680
ST. LOUIS, DEPARTMENT OF

163
00:06:05,680 --> 00:06:06,600
MOLECULAR BIOLOGY AND DIRECTOR

164
00:06:06,600 --> 00:06:09,080
OF THE CENTER FOR WOMEN'S

165
00:06:09,080 --> 00:06:10,720
INFECTIOUS DISEASE RESEARCH.

166
00:06:10,720 --> 00:06:13,560
>>THANK YOU.

167
00:06:13,560 --> 00:06:14,800
DR. JONES?

168
00:06:14,800 --> 00:06:15,920
>>HI, DR. ANDREA JONES
FROM THE

169
00:06:15,920 --> 00:06:18,120
UNIVERSITY OF NORTH CAROLINA

170
00:06:18,120 --> 00:06:21,520
CHAPEL HILL.

171
00:06:21,520 --> 00:06:24,040
>>THANK YOU.

172
00:06:24,040 --> 00:06:24,480
DR. [INDISCERNIBLE]

173
00:06:24,480 --> 00:06:25,440
>>[INDISCERNIBLE]
DIRECTOR FOR

174
00:06:25,440 --> 00:06:26,960
CENTER FOR BIOETHICS AND SOCIAL

175
00:06:26,960 --> 00:06:27,920
SCIENCES MEDICINE AT THE

176
00:06:27,920 --> 00:06:29,200
UNIVERSITY OF MICHIGAN AND ABOUT

177
00:06:29,200 --> 00:06:32,400
TO BECOME CHAIR OF RADIATION AND

178
00:06:32,400 --> 00:06:33,680
ONCOLOGY AT EMORY UNIVERSITY.

179
00:06:33,680 --> 00:06:37,360
>>THANK AND YOU

180
00:06:37,360 --> 00:06:40,240
CONGRATULATIONS, DOCTOR.

181
00:06:40,240 --> 00:06:40,600
>>DR. KLEIN.

182
00:06:40,600 --> 00:06:41,760
>>HI, SABRA KLEIN JOHN
HOPKINS

183
00:06:41,760 --> 00:06:42,840
SCHOOL OF APPROXIMATE

184
00:06:42,840 --> 00:06:43,400
UBIQUITINNATION LICK HELT,

185
00:06:43,400 --> 00:06:45,800
PROFESSOR IN THE DEPARTMENT OF

186
00:06:45,800 --> 00:06:46,480
MOLECULAR MICROBIOLOGY AND

187
00:06:46,480 --> 00:06:47,960
IMMUNOLOGY AND CO DIRECTOR OF

188
00:06:47,960 --> 00:06:49,720
THE JOHNS HOPKINS CENTER FOR

189
00:06:49,720 --> 00:06:52,280
WOMEN'S HEALTH SEX AND GENDER

190
00:06:52,280 --> 00:06:53,280
RESEARCH.

191
00:06:53,280 --> 00:07:01,480
>>THANK YOU DR. KLEIN,

192
00:07:01,480 --> 00:07:03,000
DR. Mc GREGOR?

193
00:07:03,000 --> 00:07:04,000
>>DR. Mc GREGOR HASN'T
JOINED

194
00:07:04,000 --> 00:07:04,760
US YLT.

195
00:07:04,760 --> 00:07:07,600
>>THANK YOU DR. MELENS.

196
00:07:07,600 --> 00:07:12,440
>>I'M THELLIAL CELLS MA

197
00:07:12,440 --> 00:07:14,040
MIELMENS, COLUMBIA SCHOOL OF

198
00:07:14,040 --> 00:07:16,120
PUBLIC HEALTH. 

199
00:07:16,120 --> 00:07:21,120
>>THANK YOU DOCTOR,
DOCTOR,

200
00:07:21,120 --> 00:07:21,760
DR. NOEL?

201
00:07:21,760 --> 00:07:24,520
>>GOOD MORNING EVERYONE,
I'M

202
00:07:24,520 --> 00:07:25,600
DR. ALEXANDRA NOEL, I AIVE IS

203
00:07:25,600 --> 00:07:28,120
APT PROFESSOR IN THE DEPARTMENT

204
00:07:28,120 --> 00:07:29,560
OF COMP PARAATIVE BIOMEDICAL

205
00:07:29,560 --> 00:07:32,960
SCIENCES AT LOUISIANA STATE

206
00:07:32,960 --> 00:07:33,280
UNIVERSITY.

207
00:07:33,280 --> 00:07:37,040
>>THANK YOU

208
00:07:37,040 --> 00:07:37,480
DR. [INDISCERNIBLE].

209
00:07:37,480 --> 00:07:38,920
>>HI, I'M DOCTOR

210
00:07:38,920 --> 00:07:40,200
[INDISCERNIBLE] AT UNIVERSITY OF

211
00:07:40,200 --> 00:07:42,400
COLORADO AND DIRECTOR FOR THE

212
00:07:42,400 --> 00:07:44,800
FAMILY AND WOMEN'S HEALTH

213
00:07:44,800 --> 00:07:45,040
RESEARCH.

214
00:07:45,040 --> 00:07:46,560
>>THANK YOU DR. ROBINSON?

215
00:07:46,560 --> 00:07:49,240
, IN GOOD MORNING MICHELLE

216
00:07:49,240 --> 00:07:50,480
ROBINSON, SENIOR ASSOCIATE DEAN

217
00:07:50,480 --> 00:07:52,680
DID SPECIAL INTERIM DEAN AT

218
00:07:52,680 --> 00:07:54,160
UNIVERSITY OF ALABAMA AT

219
00:07:54,160 --> 00:07:55,360
BIRMINGHAM, SCHOOL OF DENTISTRY

220
00:07:55,360 --> 00:08:00,120
AND SCHOOL OF HEDICATION.

221
00:08:00,120 --> 00:08:05,920
>>THANK YOU DR. ROBINSON.

222
00:08:05,920 --> 00:08:06,360
DR. [INDISCERNIBLE]

223
00:08:06,360 --> 00:08:08,080
>>HELLO EYE AM

224
00:08:08,080 --> 00:08:09,920
DR. [INDISCERNIBLE], DIRECTOR OF

225
00:08:09,920 --> 00:08:11,520
THE McGEE WOMEN'S RESEARCH

226
00:08:11,520 --> 00:08:12,320
INSTITUTE.

227
00:08:12,320 --> 00:08:15,640
>>THANK YOU DOCTOR, DR.
SHARPS?

228
00:08:15,640 --> 00:08:17,640
>>DR. SHARPS HASPT JOIN
USED US

229
00:08:17,640 --> 00:08:19,600
YET TODAY.

230
00:08:19,600 --> 00:08:20,520
>>DR. SIMON.

231
00:08:20,520 --> 00:08:22,520
>>HI, IT'S MELISSA, OBGYN
AT

232
00:08:22,520 --> 00:08:24,080
NORTHWEST EXPERN LEAD THE CENTER

233
00:08:24,080 --> 00:08:25,400
FOR HEALTH EQUITY

234
00:08:25,400 --> 00:08:25,760
TRANSFORMATION.

235
00:08:25,760 --> 00:08:26,400
>>THANK YOU.

236
00:08:26,400 --> 00:08:30,920
AND DR. TEMPLE TON?

237
00:08:30,920 --> 00:08:34,040
>>DR. TEMPLE TON HAS NOT
JOINED

238
00:08:34,040 --> 00:08:36,360
US YET.

239
00:08:36,360 --> 00:08:36,960
>>DR. [INDISCERNIBLE]
JOINED

240
00:08:36,960 --> 00:08:47,520
US, WOULD YOU LIKE TO INTRODUCE

241
00:08:50,040 --> 00:08:50,440
YOURSELF?

242
00:08:50,440 --> 00:08:51,080
KREBS CYCLE?

243
00:08:51,080 --> 00:08:51,960
OKAY, GOT IT.

244
00:08:51,960 --> 00:08:54,720
THANK YOU.

245
00:08:54,720 --> 00:08:55,280
THANK YOU.

246
00:08:55,280 --> 00:08:57,080
THE DOCTOR IS HAVING CONNECTION

247
00:08:57,080 --> 00:08:59,440
ISSUES BUT SHE IS IN THE MEETING

248
00:08:59,440 --> 00:09:00,080
FOR THE RECORDS.

249
00:09:00,080 --> 00:09:02,120
>>WE HAVE 1 MORE
HOUSEKEEPING

250
00:09:02,120 --> 00:09:03,360
ITEMS TO TAKE CARE OF BEFORE

251
00:09:03,360 --> 00:09:04,960
MOVING ON WITH THE MEETING.

252
00:09:04,960 --> 00:09:07,400
YOU WERE SENT THE MINUTES FROM

253
00:09:07,400 --> 00:09:09,560
THE LAST MEETING ON APRIL 6,

254
00:09:09,560 --> 00:09:10,480
2022 FOR YOUR REVIEW.

255
00:09:10,480 --> 00:09:12,600
IS THERE A MOTION ON THE TABLE

256
00:09:12,600 --> 00:09:20,960
TO ACCEPT THE APRIL 62022

257
00:09:20,960 --> 00:09:21,960
MINUTES AS WRITTEN?

258
00:09:21,960 --> 00:09:22,640
>>MOTION TO APPROVE.

259
00:09:22,640 --> 00:09:26,480
>>SORRY CAN YOU STATE
YOUR

260
00:09:26,480 --> 00:09:27,080
NAME.

261
00:09:27,080 --> 00:09:27,520
>>SABRAKLEIN.

262
00:09:27,520 --> 00:09:28,680
>>THANK YOU DR. KLEIN HAS

263
00:09:28,680 --> 00:09:31,520
SUBMITTED THE MOTION, DO I HEAR

264
00:09:31,520 --> 00:09:33,880
A SECOND?

265
00:09:33,880 --> 00:09:34,280
>>SECOND.

266
00:09:34,280 --> 00:09:39,840
>>I'M SORRY?

267
00:09:39,840 --> 00:09:40,200
>>SECOND.

268
00:09:40,200 --> 00:09:40,560
>>DR. JAGSY.

269
00:09:40,560 --> 00:09:42,800
>>THANK YOU VERY MUCH.

270
00:09:42,800 --> 00:09:52,800
THE POLL HAS BEEN OPENED FOR YOU

271
00:09:52,800 --> 00:09:53,320
TO RESPOND.

272
00:09:53,320 --> 00:10:01,080
IF YOU ARE IN FAVOR, OPPOSE, OR

273
00:10:01,080 --> 00:10:11,480
ABSTAIN, YOU WILL HAVE

274
00:10:12,400 --> 00:10:22,920
30-SECONDS TO RESPOND.

275
00:10:22,920 --> 00:10:25,200
>>HI, SARAH HAVE THE
VOTES BEEN

276
00:10:25,200 --> 00:10:25,440
RECORDED.

277
00:10:25,440 --> 00:10:26,880
>>YES WITH 14 IN FAVOR.

278
00:10:26,880 --> 00:10:28,880
>>THANK YOU.

279
00:10:28,880 --> 00:10:30,960
THE APPROXIMATELY SIXTH 2022

280
00:10:30,960 --> 00:10:33,840
MEETING MINUTES HAVE BEEN

281
00:10:33,840 --> 00:10:37,480
ACCEPTED WITH 14 IN FAVOR.

282
00:10:37,480 --> 00:10:38,280
DR. Mc GREGOR, YOU JUST

283
00:10:38,280 --> 00:10:39,480
JOINED, WOULD YOU LIKE TO

284
00:10:39,480 --> 00:10:47,120
INTRODUCE YOURSELF BEFORE WE

285
00:10:47,120 --> 00:10:47,400
START?

286
00:10:47,400 --> 00:10:50,680
>>SURE, YES, THANK YOU,
ALLYSON

287
00:10:50,680 --> 00:10:51,840
Mc GREGOR, PROFESSOR OF

288
00:10:51,840 --> 00:10:53,240
MEDICINE AND ASSOCIATE DEAN AT

289
00:10:53,240 --> 00:10:54,240
FACT OUTLETY AFFAIRS AND

290
00:10:54,240 --> 00:10:55,040
DEVELOPMENT AT THE UNIVERSITY OF

291
00:10:55,040 --> 00:10:56,880
SOUTH CAROLINA IN GREENVILLE.

292
00:10:56,880 --> 00:10:58,000
>>THANK YOU DR. Mc GREGOR
AND

293
00:10:58,000 --> 00:10:59,720
NOW I WOULD LIKE TO INTRODUCE

294
00:10:59,720 --> 00:11:00,800
THE CHAIR OF THIS COMMITTEE AND

295
00:11:00,800 --> 00:11:03,440
THE DIRECTOR OF THE OFFICE OF

296
00:11:03,440 --> 00:11:07,440
RESEARCH ON WOMEN'S HEALTH

297
00:11:07,440 --> 00:11:08,720
DR. JANINE CLAYTON.

298
00:11:08,720 --> 00:11:11,600
>>THANK YOU SO MUCH DR.
NOURSI.

299
00:11:11,600 --> 00:11:15,800
LET ME SHARE MY KREEN HERE AND

300
00:11:15,800 --> 00:11:26,360
WE WILL--SCREEN HERE AND WE WILL

301
00:11:29,440 --> 00:11:30,200
GET STARTED.

302
00:11:30,200 --> 00:11:32,240
CAN SOMEONE PLEASE CONFIRM YOU

303
00:11:32,240 --> 00:11:34,480
ARE SEEING THE CORRECT SCREEN.

304
00:11:34,480 --> 00:11:34,760
>>YES,.

305
00:11:34,760 --> 00:11:35,320
>>LOOKS GOOD.

306
00:11:35,320 --> 00:11:35,800
>>AWESOME.

307
00:11:35,800 --> 00:11:36,840
THANK YOU SO MUCH.

308
00:11:36,840 --> 00:11:38,440
I AM SO EXCITED TO BE HERE WITH

309
00:11:38,440 --> 00:11:40,280
YOU ALL HERE TODAY FOR AWE

310
00:11:40,280 --> 00:11:41,160
57th MEETING.

311
00:11:41,160 --> 00:11:46,080
HERE'S MY OUTLINE FOR TODAY, I

312
00:11:46,080 --> 00:11:48,720
WILL COVER SO ORWH AND NIH

313
00:11:48,720 --> 00:11:50,360
UPDATES, SOME UPDATES ON COVID,

314
00:11:50,360 --> 00:11:52,240
SCIENTIFIC AND POLICY UPDATES,

315
00:11:52,240 --> 00:11:53,520
TALK ABOUT FUNDING AND CAREERS

316
00:11:53,520 --> 00:11:54,120
BEFORE I CLOSE.

317
00:11:54,120 --> 00:11:56,000
SO WITH THAT, LET ME GO RIGHT

318
00:11:56,000 --> 00:11:58,640
AHEAD AND I WILL START WITH AN

319
00:11:58,640 --> 00:12:03,880
ANNOUNCEMENT THAT YOU ARE ALL

320
00:12:03,880 --> 00:12:08,040
AWARE OF, DR. ANTHONY FAUCI

321
00:12:08,040 --> 00:12:10,400
ANNOUNCED HIS INTENTION TO

322
00:12:10,400 --> 00:12:12,520
RETIRE IN SEPTEMBER AND HE

323
00:12:12,520 --> 00:12:13,680
PROVIDED INCREDIBLE ADVANCES IN

324
00:12:13,680 --> 00:12:14,400
WOMEN'S HEALTH.

325
00:12:14,400 --> 00:12:16,280
I WANTED TO HIGHLIGHT A FEW OF

326
00:12:16,280 --> 00:12:16,480
THOSE.

327
00:12:16,480 --> 00:12:20,240
FROM HIS GROUND BREAKING

328
00:12:20,240 --> 00:12:22,760
RESEARCH ON GRANUE LO MATOSEIS,

329
00:12:22,760 --> 00:12:24,520
TO UNDERSTANDING AND REGULATION

330
00:12:24,520 --> 00:12:26,840
AND MECHANISMS OF ACTIONS OF

331
00:12:26,840 --> 00:12:28,200
MANY OF THE IMMUNOSUPPRESSIVE

332
00:12:28,200 --> 00:12:29,320
MEDICATIONS WE USE TODAY AND

333
00:12:29,320 --> 00:12:35,160
THAT I PERSONALLY USE TO TREAT

334
00:12:35,160 --> 00:12:37,080
WEGENER'S PATIENTS AND WE ARE

335
00:12:37,080 --> 00:12:38,160
GRATEFUL FOR HIS INCREDIBLE WORK

336
00:12:38,160 --> 00:12:41,160
IN THAT SPACE AND HIS LEADERSHIP

337
00:12:41,160 --> 00:12:43,440
AT NIAID HAS RESULTED IN

338
00:12:43,440 --> 00:12:44,680
INCREDIBLE ADVANCES RELATED TO

339
00:12:44,680 --> 00:12:47,440
HIV, 1 OF THEM BEING PREVENTION

340
00:12:47,440 --> 00:12:49,200
OF TRANSMISSION OF HIV FROM

341
00:12:49,200 --> 00:12:53,840
MOTHER TO CHILD, SO THAT IS

342
00:12:53,840 --> 00:12:55,880
BASICALLY SOMETHING'S WE TAKE

343
00:12:55,880 --> 00:12:57,920
ALMOST FOR GRANTED NOW BUT WAS

344
00:12:57,920 --> 00:12:59,520
NOT ALWAYS THE CASE, HIS

345
00:12:59,520 --> 00:13:01,160
LEADERSHIP IN THAT SPACE LED TO

346
00:13:01,160 --> 00:13:05,920
THESE ADVANCES WHERE WE CAN NOW

347
00:13:05,920 --> 00:13:07,400
SAFELY HIV POSITIVE INDIVIDUALS

348
00:13:07,400 --> 00:13:10,760
CAN NOW SAFELY HAVE A PREGNANCY

349
00:13:10,760 --> 00:13:11,560
AND PREVENT MOTHER-CHILD

350
00:13:11,560 --> 00:13:12,720
TRANSMISSION OF HIV.

351
00:13:12,720 --> 00:13:15,720
IN ADDITION, THROUGH HIS WORK

352
00:13:15,720 --> 00:13:17,720
AND OVERSIGHT OF INFLUENZA

353
00:13:17,720 --> 00:13:19,560
CHALLENGE STUDIES, WORK THAT HAS

354
00:13:19,560 --> 00:13:20,720
ADVANCED OUR UNDERSTANDING OF

355
00:13:20,720 --> 00:13:23,840
SEX DIFFERENCES IN THE IMMUNE

356
00:13:23,840 --> 00:13:25,480
RESPONSE TO INFLUENZA AND SO WE

357
00:13:25,480 --> 00:13:27,480
KNOW THERE ARE SEX DIFFERENCES

358
00:13:27,480 --> 00:13:28,520
IN IMMUNE RESPONSES.

359
00:13:28,520 --> 00:13:29,960
THAT'S BEEN WELL RECOGNIZED AND

360
00:13:29,960 --> 00:13:32,200
WE KNOW THAT INDIVIDUALS HAVE

361
00:13:32,200 --> 00:13:33,640
BECOME PREGNANT HAVE INCREASED

362
00:13:33,640 --> 00:13:35,960
RISKS RELATED TO INFLUENZA BUT

363
00:13:35,960 --> 00:13:37,080
THESE RECENT CHALLENGE STUDIES

364
00:13:37,080 --> 00:13:38,760
THAT WERE PUBLISHED LAST YEAR

365
00:13:38,760 --> 00:13:40,880
HIGHLIGHT SOME OF THE UNDERLYING

366
00:13:40,880 --> 00:13:45,160
MECHANISMS RELATED TO THAT AND

367
00:13:45,160 --> 00:13:47,360
THE FACT THAT INHIBITION TITERS

368
00:13:47,360 --> 00:13:48,440
WERE ASSOCIATED WITH THE SEX

369
00:13:48,440 --> 00:13:49,200
DIFFERENCES THAT WE'RE SEEING

370
00:13:49,200 --> 00:13:51,000
AND SO THAT GIVES US A CLUE AS

371
00:13:51,000 --> 00:13:53,680
TO SOME OF THE MECHANISMS THAT

372
00:13:53,680 --> 00:13:54,880
MAYBE EVEN MEET THE SEX

373
00:13:54,880 --> 00:13:56,240
DIFFERENCES THAT HAVE BEEN

374
00:13:56,240 --> 00:13:57,000
RECOGNIZED FOR SOMETIME.

375
00:13:57,000 --> 00:13:59,000
AND THEN LASTLY INCLUES OF

376
00:13:59,000 --> 00:14:01,720
PREGNANT PEOPLE IN COVID-19

377
00:14:01,720 --> 00:14:03,160
RESEARCH, PREGNANT WOMEN AND

378
00:14:03,160 --> 00:14:04,720
YOUNG CHILDREN ARE NOT INCLUDED

379
00:14:04,720 --> 00:14:08,120
IN EARLY EXPERIMENTAL STUDIES

380
00:14:08,120 --> 00:14:10,160
RELATED TO VACCINATIONS BUT I DO

381
00:14:10,160 --> 00:14:12,760
APPLAUD NIAID FOR DEVELOPING THE

382
00:14:12,760 --> 00:14:15,120
MOMMY VAX STUDY WHERE REGNANT

383
00:14:15,120 --> 00:14:17,000
WOMEN ARE INCLUDED AND--PREGNANT

384
00:14:17,000 --> 00:14:18,840
WOMEN ARE INCLUDED AND LOOKING

385
00:14:18,840 --> 00:14:22,080
AT EFFECTS OF COVID-19 VACCINE

386
00:14:22,080 --> 00:14:24,040
TO PREGNANTINANT PEOPLE AND

387
00:14:24,040 --> 00:14:24,760
POSTPARTUM INDIVIDUALS AND WE

388
00:14:24,760 --> 00:14:26,240
LOOK FORWARD TO THE RESULTS OF

389
00:14:26,240 --> 00:14:28,040
THOSE STUDIES GOING FORWARD AND

390
00:14:28,040 --> 00:14:31,920
ARE WE CONGRATULATE DR. FAUCI ON

391
00:14:31,920 --> 00:14:33,480
HIS COMMITMENT TO WOMEN'S HEALTH

392
00:14:33,480 --> 00:14:34,000
RESEARCH.

393
00:14:34,000 --> 00:14:36,120
SO THAT'S THE WEGENER'S PAPER

394
00:14:36,120 --> 00:14:42,200
FROM MANY YEARS AGO AND FROM

395
00:14:42,200 --> 00:14:44,360
DR. FAUCI, RELATED TO HIV

396
00:14:44,360 --> 00:14:45,920
TRANSMISSION, SOME INFLUENZA

397
00:14:45,920 --> 00:14:50,760
VIRION LIKE PARTICLES AND THEN

398
00:14:50,760 --> 00:14:52,080
JUST SOME MORE ON COVID-19.

399
00:14:52,080 --> 00:14:53,960
SO AS I MOVE THIS OVER TO THE

400
00:14:53,960 --> 00:14:55,560
UPDATE SECTION, I WANT TO SHARE

401
00:14:55,560 --> 00:14:56,480
SOME NEWS WITH YOU.

402
00:14:56,480 --> 00:15:01,680
FIRST WE HAVE A NEW ASSISTANT

403
00:15:01,680 --> 00:15:02,600
DIRECTOR AT ORWH, MISS

404
00:15:02,600 --> 00:15:04,240
[INDISCERNIBLE] IS OUR NEW

405
00:15:04,240 --> 00:15:05,440
ASSISTANT DIRECTOR FOR

406
00:15:05,440 --> 00:15:07,120
MANAGEMENT REPORTING OPERATIONS

407
00:15:07,120 --> 00:15:08,120
AND COMMUNICATIONS SECTION.

408
00:15:08,120 --> 00:15:11,440
WE STREAMLINED THAT AND WE

409
00:15:11,440 --> 00:15:14,360
WELCOME HER SECOND AS YOU KNOW,

410
00:15:14,360 --> 00:15:15,560
WE ARE CURRENTLY UNDERGOING THE

411
00:15:15,560 --> 00:15:17,200
PROCESS OF UPDATING THE NIH WIDE

412
00:15:17,200 --> 00:15:19,960
STRAY JECTORY STIGIC PLAN FOR

413
00:15:19,960 --> 00:15:21,440
THE RESEARCH ON WOMEN AND OF

414
00:15:21,440 --> 00:15:25,960
COURSE THERE HAVE BEEN RECENT

415
00:15:25,960 --> 00:15:27,680
SIGNIFICANT HEALTH EEIVETS

416
00:15:27,680 --> 00:15:29,400
INCLUDING THE COVID-19 PANDEMIC

417
00:15:29,400 --> 00:15:30,600
THAT HAVE HAD AN OUTSIDE EFFECT

418
00:15:30,600 --> 00:15:32,920
ON WOMEN, SEVERAL TOPICS

419
00:15:32,920 --> 00:15:37,240
RELATIVE TO THE HEALTH OF WOMEN

420
00:15:37,240 --> 00:15:38,640
WERE REVIEWED BY THE BY THE

421
00:15:38,640 --> 00:15:39,680
COMMITTEE AT THE CONFERENCE LAST

422
00:15:39,680 --> 00:15:41,120
YEAR, THAT WAS CONGRESSALLY

423
00:15:41,120 --> 00:15:42,400
DIRECTED.

424
00:15:42,400 --> 00:15:44,040
I WANT TO HIGHLIGHT THAT THE

425
00:15:44,040 --> 00:15:45,800
FULL REPORT IS AVAILABLE ON OUR

426
00:15:45,800 --> 00:15:46,160
WEBSITE.

427
00:15:46,160 --> 00:15:49,960
THAT INFORMATION ALONG WITH

428
00:15:49,960 --> 00:15:51,800
OTHER INFORMATION FROM A WIDE

429
00:15:51,800 --> 00:15:54,160
RANGE OF STAKEHOLDERS WILL BEGIN

430
00:15:54,160 --> 00:15:55,920
FORMING THE NEXT STRATEGIC PLAN

431
00:15:55,920 --> 00:15:57,080
FOR THE HEALTH AND RESEARCH ON

432
00:15:57,080 --> 00:16:00,080
WOMEN OR WE RECENTLY CLOSED OR

433
00:16:00,080 --> 00:16:02,560
SOLICITED INPUT FROM A LARGE SET

434
00:16:02,560 --> 00:16:03,760
OF THE PUBLIC AND BASICALLY

435
00:16:03,760 --> 00:16:05,840
ANYONE WHO WANTED TO RESPOND TO

436
00:16:05,840 --> 00:16:07,800
INFORM OUR NEXT STEPS.

437
00:16:07,800 --> 00:16:09,760
SO THANK YOU VERY MUCH FOR YOUR

438
00:16:09,760 --> 00:16:13,640
WORK ON THAT ACR WH AND STAY

439
00:16:13,640 --> 00:16:14,280
TUNED FOR MORE.

440
00:16:14,280 --> 00:16:17,360
NEXT, I WANT TO HIGHLIGHT FOR

441
00:16:17,360 --> 00:16:19,920
YOU SOME CHANGES THAT NIH

442
00:16:19,920 --> 00:16:21,480
REQUESTED RELATED TO THE

443
00:16:21,480 --> 00:16:22,120
BIENNIAL REPORT.

444
00:16:22,120 --> 00:16:25,000
THIS IS YOUR REPORT, THE TITLE,

445
00:16:25,000 --> 00:16:26,560
OFFICIAL REPORT IS THE REPORT OF

446
00:16:26,560 --> 00:16:27,960
THE ADVISE RECOMMITTEE ON

447
00:16:27,960 --> 00:16:28,920
WOMEN'S HEALTH, RESEARCH ON

448
00:16:28,920 --> 00:16:31,040
WOMEN'S HEALTH AND AS A RESULT

449
00:16:31,040 --> 00:16:34,280
WE ARE PROPOSING TO SHORTEN THE

450
00:16:34,280 --> 00:16:36,240
LENGTH OF THIS REPORT WITH A

451
00:16:36,240 --> 00:16:37,640
TARGET PAGE COUNT OF FEWER THAN

452
00:16:37,640 --> 00:16:39,280
A HUNDRED PAGES AND WITH A

453
00:16:39,280 --> 00:16:44,320
SINGLE PAGE FOR EACH ICU AS A

454
00:16:44,320 --> 00:16:47,600
STRATEGY, WE ARE SEEKING TO

455
00:16:47,600 --> 00:16:48,720
LEVERAGE EXISTING DIGITAL

456
00:16:48,720 --> 00:16:49,840
CONTENT AND DIGITAL CONTENT IN

457
00:16:49,840 --> 00:16:51,000
GENERAL TO INSURE THAT THE

458
00:16:51,000 --> 00:16:52,480
PUBLIC HAS ACCESS TO INFORMATION

459
00:16:52,480 --> 00:16:54,800
THAT THEY NEED. 

460
00:16:54,800 --> 00:16:55,960
WE KNOW THAT THIS IMPORTANT

461
00:16:55,960 --> 00:16:58,960
REPORT, IT HAS BEEN THE SOURCE

462
00:16:58,960 --> 00:17:00,760
OF INFORMATION FOR MANY OTHER

463
00:17:00,760 --> 00:17:02,200
STUDIES AND IT'S IMPORTANT FOR

464
00:17:02,200 --> 00:17:03,600
US TO TRANSPARENTLY SHARE WITH

465
00:17:03,600 --> 00:17:05,440
THE PUBLIC INFORMATION ABOUT

466
00:17:05,440 --> 00:17:08,040
THEIR INVESTMENT IN WOMEN'S

467
00:17:08,040 --> 00:17:10,840
HEALTH RESEARCH, FOR EXAMPLE,

468
00:17:10,840 --> 00:17:11,840
RECENT NATIONAL ACADEMY'S REPORT

469
00:17:11,840 --> 00:17:13,480
ON WOMEN ON UNDER REP

470
00:17:13,480 --> 00:17:14,480
REPRESENTED GROUPS USED

471
00:17:14,480 --> 00:17:17,840
INCLUSION DATA THAT WE REPORT IN

472
00:17:17,840 --> 00:17:20,040
THE BIENNIAL REPORT TO DO THEIR

473
00:17:20,040 --> 00:17:20,800
ANALYSIS.

474
00:17:20,800 --> 00:17:24,320
WE WILL ALSO BE USING THE START

475
00:17:24,320 --> 00:17:26,000
MODULE WHICH STANDS FOR

476
00:17:26,000 --> 00:17:26,960
STRATEGIC PLAN TRACKING AND

477
00:17:26,960 --> 00:17:29,120
REPORTING TOOL THAT THE OFFICE

478
00:17:29,120 --> 00:17:32,360
OF EVALUATION, PERFORMANCE AND

479
00:17:32,360 --> 00:17:35,640
REPORTING OF OE, PR IN DPC SI,

480
00:17:35,640 --> 00:17:37,600
IS OVERSEEING TO BE ABLE TO

481
00:17:37,600 --> 00:17:38,400
FACILITATE INFORMATION, GETTING

482
00:17:38,400 --> 00:17:40,880
INFORMATION IN A CONSISTENT

483
00:17:40,880 --> 00:17:43,080
MANNER ACROSS THE NIH ICOs AND

484
00:17:43,080 --> 00:17:44,840
TO BE ABLE TO LEVERAGE DATA FROM

485
00:17:44,840 --> 00:17:46,640
A VARIETY OF SOURCES AS WE MOVE

486
00:17:46,640 --> 00:17:47,080
FORWARD.

487
00:17:47,080 --> 00:17:49,880
SO YOU WILL BE--YOU WILL RECALL

488
00:17:49,880 --> 00:17:52,040
ACRWH MEMBERS THAT YOU RESCREW

489
00:17:52,040 --> 00:17:53,480
THE CONTENT FOR THE BIENNIAL

490
00:17:53,480 --> 00:17:56,720
REPORT AND YOU WILL BE SEEING

491
00:17:56,720 --> 00:17:57,880
THAT AGAIN IN EARLY 2023 ANDY

492
00:17:57,880 --> 00:18:00,120
WOO WILL HAVE A NEW E-MAIL

493
00:18:00,120 --> 00:18:01,680
ADDRESS THAT YOU WILL BE

494
00:18:01,680 --> 00:18:03,120
RECEIVING INFORMATION FROM AND

495
00:18:03,120 --> 00:18:04,480
TELL BE BIENNIAL REPORT

496
00:18:04,480 --> 00:18:06,960
UNDERSCORE HELP OF WOMEN AT

497
00:18:06,960 --> 00:18:11,160
NIH.GOV SO KEEP YOUR EYE OUT FOR

498
00:18:11,160 --> 00:18:11,640
THAT AS WELL.

499
00:18:11,640 --> 00:18:14,560
IN TERMS OF THE LEADERSHIP YOU

500
00:18:14,560 --> 00:18:16,120
UPDATES DR. JIM ANDERSON WHO WAS

501
00:18:16,120 --> 00:18:18,840
THE FORMER DEPUTY DIRECTOR FOR

502
00:18:18,840 --> 00:18:21,360
PROGRAM ACCORD NATION PLANNING

503
00:18:21,360 --> 00:18:22,640
AND STRATEGIC INITIATIVES HERE

504
00:18:22,640 --> 00:18:27,520
AT NIH, HE RECENTLY RETIRED AND

505
00:18:27,520 --> 00:18:29,320
WE ARE PLEASED TO SHARE WITH YOU

506
00:18:29,320 --> 00:18:33,960
THAT THE ACTING DIRECTOR IS

507
00:18:33,960 --> 00:18:36,400
DR. ROBERT EISINGER, HE WAS A

508
00:18:36,400 --> 00:18:38,280
LONG-TERM DIRECTOR OF OHR, AND

509
00:18:38,280 --> 00:18:39,800
WORKED THERE FOR MANY YEARS AND

510
00:18:39,800 --> 00:18:41,200
WE'RE DELIGHTED TO BE WORKING

511
00:18:41,200 --> 00:18:43,000
WITH HIM IN THIS NEW CAPACITY

512
00:18:43,000 --> 00:18:44,480
AND I'M REALLY THRILLED TO SHARE

513
00:18:44,480 --> 00:18:50,240
WITH YOU THAT DR. MONICA

514
00:18:50,240 --> 00:18:51,640
BERTAGNOLLI, HAS RECENTLY FIRST

515
00:18:51,640 --> 00:18:52,640
STARTED AS THE FIRST WOMAN

516
00:18:52,640 --> 00:18:55,680
DIRECTOR OF THE NIH AND WE ARE

517
00:18:55,680 --> 00:18:59,560
NOW UP TO 12 WOMEN IC DIRECTORS.

518
00:18:59,560 --> 00:19:03,640
MISS ANDREA NORRIS IS RETIRING

519
00:19:03,640 --> 00:19:06,240
AND SO SHE ANNOUNCED HER

520
00:19:06,240 --> 00:19:07,520
INTENTION TO RETIRE IN DECEMBER,

521
00:19:07,520 --> 00:19:09,000
AND I'M ALSO PLEASED TO SHARE

522
00:19:09,000 --> 00:19:12,200
WITH YOU THAT DR. NINA SHORE HAS

523
00:19:12,200 --> 00:19:13,960
BEEN APPOINTED DEPUTY DIRECTOR

524
00:19:13,960 --> 00:19:15,320
FOR INTRAMURAL RESEARCH AND WE

525
00:19:15,320 --> 00:19:17,000
ARE EXCITED ABOUT WORKING WITH

526
00:19:17,000 --> 00:19:19,720
HER IN THAT CAPACITY AND

527
00:19:19,720 --> 00:19:21,120
CONGRATULATION DR. MICHAEL

528
00:19:21,120 --> 00:19:23,240
GOTTESMAN FOR HIS LONG-TERM

529
00:19:23,240 --> 00:19:23,640
CAREER.

530
00:19:23,640 --> 00:19:24,840
MR. KEVIN WILLIAMS IS NOW THE

531
00:19:24,840 --> 00:19:27,200
NEW DIRECTOR OF THE OFFICE OF

532
00:19:27,200 --> 00:19:28,840
EQUITY, DIVERSITY AND INCLUSION

533
00:19:28,840 --> 00:19:31,080
AS WELL. 

534
00:19:31,080 --> 00:19:32,280
AND SO, I LOOK FORWARD TO

535
00:19:32,280 --> 00:19:33,920
WORKING WITH ALL OF THESE NEW

536
00:19:33,920 --> 00:19:38,320
LEADERS AT NE H IN THEIR NEW

537
00:19:38,320 --> 00:19:38,720
CAPACITIES.

538
00:19:38,720 --> 00:19:40,200
IN TERMS OF COVID-19 UPDATE, I

539
00:19:40,200 --> 00:19:46,640
WANT  TO SHARE WITH YOU, EACH OF

540
00:19:46,640 --> 00:19:49,800
THESE MEETINGS WE'VE SHARED

541
00:19:49,800 --> 00:19:50,640
COVID-19 DATA RELATIVE TO THE

542
00:19:50,640 --> 00:19:52,200
HEALTH OF WOMEN AND THIS TIME I

543
00:19:52,200 --> 00:19:53,440
WANT TO SHARE INFORMATION WITH

544
00:19:53,440 --> 00:19:54,640
YOU ON A REVIEW ARTICLE THAT

545
00:19:54,640 --> 00:19:56,200
LOOKED ACROSS ALL THE

546
00:19:56,200 --> 00:19:58,720
PUBLICATIONS RELATED TO COVID-19

547
00:19:58,720 --> 00:19:59,560
OVER THE LAST 2 YEARS.

548
00:19:59,560 --> 00:20:02,280
THEY IEE, AUDIENCE DENTIFIED

549
00:20:02,280 --> 00:20:04,160
OVER 4000 PUBLICATIONS THAT MET

550
00:20:04,160 --> 00:20:06,360
THEIR CRITERIA, THEY WERE

551
00:20:06,360 --> 00:20:08,560
SPECIFICALLY LOOKING FOR

552
00:20:08,560 --> 00:20:10,960
PUBLICATIONS THAT REPORTED

553
00:20:10,960 --> 00:20:13,280
OUTCOMES FOR SEX, BOY SEX.

554
00:20:13,280 --> 00:20:15,760
AND UNFORTUNATELY, AND THEY WERE

555
00:20:15,760 --> 00:20:17,120
LOOKING FOR, PUBLICATIONS THAT

556
00:20:17,120 --> 00:20:19,960
LOOK AT COVID SEQUEL I AS WELL

557
00:20:19,960 --> 00:20:26,480
AS LONG COVID SYNDROME AS THEY

558
00:20:26,480 --> 00:20:29,080
PUBLISHED IN THIS PUBLICATION,

559
00:20:29,080 --> 00:20:31,440
AND UNFORTUNATELY ON ONLY 23 OF

560
00:20:31,440 --> 00:20:33,440
THESE OVER 4000 PUBLICATIONS

561
00:20:33,440 --> 00:20:34,160
REPORTED RESULTS SEPARATELY FOR

562
00:20:34,160 --> 00:20:37,320
MEN AND WOMEN AND THEY DID FIND

563
00:20:37,320 --> 00:20:42,160
THAT WOMEN WERE MORE LIKELY TO

564
00:20:42,160 --> 00:20:50,360
REPORT COVID SEQUEL I RELATED TO

565
00:20:50,360 --> 00:20:51,680
ENT, PSYCHIATRIC, MOOD, AND

566
00:20:51,680 --> 00:20:54,520
OTHERS, AND IN TERMS OF LONG

567
00:20:54,520 --> 00:20:56,720
COVID SYNDROME, ONLY 12 OF THOSE

568
00:20:56,720 --> 00:20:59,160
4000 PUBLICATIONS HAD

569
00:20:59,160 --> 00:21:00,000
INFORMATION AVAILABLE

570
00:21:00,000 --> 00:21:00,760
DISAGGREGATED BY SEX.

571
00:21:00,760 --> 00:21:03,160
WOMEN WERE MORE LIKELY TO HAVE

572
00:21:03,160 --> 00:21:05,080
LONG ASHING SYNDROME IN THIS

573
00:21:05,080 --> 00:21:07,240
REVIEW, THIS LITERATURE REVIEW

574
00:21:07,240 --> 00:21:08,080
AND SIGNIFICANTLY MORE LIKELY

575
00:21:08,080 --> 00:21:11,320
AMONG WOMEN IN THE LONG COVID

576
00:21:11,320 --> 00:21:14,680
SECTION INCLUDED GI,

577
00:21:14,680 --> 00:21:15,640
NEUROLOGICAL AND DERMATOLOGICAL

578
00:21:15,640 --> 00:21:17,360
COMPLIICATIONS AND AMONG MEMORY

579
00:21:17,360 --> 00:21:18,760
RESPONSE ENDOCRINE COMPLICATIONS

580
00:21:18,760 --> 00:21:22,920
IN LONG COVID IN ADDITION TO THE

581
00:21:22,920 --> 00:21:23,640
RENAL COMPLICATIONS.

582
00:21:23,640 --> 00:21:26,960
SO A FEW STUDIES, THIS REVIEW

583
00:21:26,960 --> 00:21:30,080
SUMMARIZES FEW COVID-19 STUDIES

584
00:21:30,080 --> 00:21:32,360
REPORTS SEX DISAGGREGATED DATA

585
00:21:32,360 --> 00:21:35,640
UNDERSCORING THE NEED FOR BASED

586
00:21:35,640 --> 00:21:36,440
SEX RESEARCH REPORTING.

587
00:21:36,440 --> 00:21:39,560
AND I AM HIGHLIGHTING THIS STUDY

588
00:21:39,560 --> 00:21:39,880
FROM ITALY.

589
00:21:39,880 --> 00:21:42,240
ALTHOUGH THE STUDY IS SMALL, IT

590
00:21:42,240 --> 00:21:43,520
PROSPECTIVELY LOOKED AT OUTCOMES

591
00:21:43,520 --> 00:21:46,600
BY SEX AND FOUND THAT FEMALE SEX

592
00:21:46,600 --> 00:21:48,720
ADVANCED AGE AND ACTIVE SMOKING

593
00:21:48,720 --> 00:21:54,320
WERE LINKED TO HIGHER RISKS OF

594
00:21:54,320 --> 00:21:55,120
LONG COVID ALTHOUGH DISPARITY

595
00:21:55,120 --> 00:21:56,240
AND DISEASE WAS NOT.

596
00:21:56,240 --> 00:21:58,680
SO APPLAUD THOSE INVESTIGATORS

597
00:21:58,680 --> 00:22:01,360
FOR DOING THAT PROSPECTIVELY.

598
00:22:01,360 --> 00:22:03,200
I DO WANT TO SHARE UPDATES IN

599
00:22:03,200 --> 00:22:05,440
TERMS OF NIH INVESTMENTS IN THIS

600
00:22:05,440 --> 00:22:07,080
SPACE, THE RECOVER STUDY OVER

601
00:22:07,080 --> 00:22:09,240
SEARCHING COVID TO ENHANCE

602
00:22:09,240 --> 00:22:12,920
RECOVERY IS LOOKING FOR SEX

603
00:22:12,920 --> 00:22:16,680
OUTCOMES IN COVID-19 INFECTION

604
00:22:16,680 --> 00:22:18,960
AS WELL AS P A SC AS WELL, AND

605
00:22:18,960 --> 00:22:20,920
IT'S LOOKING INCLUDING A LARGE

606
00:22:20,920 --> 00:22:23,080
NUMBER OF INDIVIDUALS, ADULTS

607
00:22:23,080 --> 00:22:26,920
AND PEDIATRIC COHORTS ARE

608
00:22:26,920 --> 00:22:29,000
INCLUDED AND LOOKING AT OVER

609
00:22:29,000 --> 00:22:34,400
60 MILLION ELECTRONIC HEALTH

610
00:22:34,400 --> 00:22:34,640
RECORDS.

611
00:22:34,640 --> 00:22:37,600
THERE'S AN ACUTE INFECTION

612
00:22:37,600 --> 00:22:39,400
COHORT MPLET THERE'S A PAST

613
00:22:39,400 --> 00:22:41,040
COHORT THAT INCLUDES, WILL

614
00:22:41,040 --> 00:22:42,840
INCLUDE OVER 200 PLUS PREGNANT

615
00:22:42,840 --> 00:22:46,360
PERSONS AND OVER A THOUSAND

616
00:22:46,360 --> 00:22:48,280
CHILDREN AND THERE'S THIS POST

617
00:22:48,280 --> 00:22:52,600
ACUTE INFECTION COHORT THAT I

618
00:22:52,600 --> 00:22:54,360
MENTIONED AND HAS BEEN IN A CASE

619
00:22:54,360 --> 00:22:57,000
CONTROL DESIGN AND IT HAS

620
00:22:57,000 --> 00:22:58,120
PROSPECTIVELY PLANNING TO LOOK

621
00:22:58,120 --> 00:23:00,800
CAREFULLY AT SOME OF THESE

622
00:23:00,800 --> 00:23:01,400
OUTCOMES BY SPECS.

623
00:23:01,400 --> 00:23:03,480
HERE IS A BIT MORE INFORMATION

624
00:23:03,480 --> 00:23:05,440
ON RECOVER AND THE PREGNANT

625
00:23:05,440 --> 00:23:09,240
INDIVIDUALS THAT WILL BE

626
00:23:09,240 --> 00:23:10,520
INCLUDED.

627
00:23:10,520 --> 00:23:12,160
RECOVER IS LEVERAGING 2

628
00:23:12,160 --> 00:23:15,360
PREGNANCY COHORTS, THE MFM U

629
00:23:15,360 --> 00:23:21,800
UNITS LAZ AS PREGNANCY CORONA

630
00:23:21,800 --> 00:23:23,160
VIRUS PREGNANCY AND OUTCOMES AND

631
00:23:23,160 --> 00:23:24,720
WE LOOK TO THOSE TO HAVE

632
00:23:24,720 --> 00:23:26,280
EVIDENCE TO INFORM TREATMENT

633
00:23:26,280 --> 00:23:26,560
DECISIONS.

634
00:23:26,560 --> 00:23:28,520
THE PROTOCOLS ARE COLLECTING

635
00:23:28,520 --> 00:23:29,720
INFORMATION ABOUT PREGNANCY,

636
00:23:29,720 --> 00:23:31,400
PREGNANCY RELATED OUTCOMES AS

637
00:23:31,400 --> 00:23:34,240
WELL AS FEMALE SPECIFIC OUTCOMES

638
00:23:34,240 --> 00:23:37,760
INCLUDING MENSTRUATION,

639
00:23:37,760 --> 00:23:39,120
MENOPAUSE, SYMPTOMS, FERTILITY

640
00:23:39,120 --> 00:23:39,680
AND SECTION FUNCTION.

641
00:23:39,680 --> 00:23:41,440
TO GIVE YOU A BIT OF AN UPATE ON

642
00:23:41,440 --> 00:23:46,040
SOME OF THE ORWH-LED RELATED

643
00:23:46,040 --> 00:23:47,000
ACTESTIFIES, RELATED TO

644
00:23:47,000 --> 00:23:48,240
COVID-19, WE FORMED A WORKING

645
00:23:48,240 --> 00:23:50,280
GROUP THROUGH THE NIH

646
00:23:50,280 --> 00:23:52,400
COORDINATING COMMITTEE OR CCRWH

647
00:23:52,400 --> 00:23:55,480
FOR COVID-19 AND THE HEALTH OF

648
00:23:55,480 --> 00:23:56,440
WOMEN.

649
00:23:56,440 --> 00:23:58,960
THIS GROUP PERFORMED A PORTFOLIO

650
00:23:58,960 --> 00:24:00,280
ANALYSIS LOOKING AT RESEARCH

651
00:24:00,280 --> 00:24:04,240
GRANTS AWARDED OVER A SEVERAL

652
00:24:04,240 --> 00:24:05,560
MONTH PERIOD, AND ACTUALLY

653
00:24:05,560 --> 00:24:10,840
THIS--THAT SHOULD BE A 2 YEAR

654
00:24:10,840 --> 00:24:12,520
PERIOD AND SO, THEY LOOKED WE

655
00:24:12,520 --> 00:24:15,680
WERE TRYING TO ACCELERATE THE

656
00:24:15,680 --> 00:24:17,080
EFFECTS ON SEC AND GENDER AND

657
00:24:17,080 --> 00:24:18,840
THAT WAS THE GROUP'S GOAL AND

658
00:24:18,840 --> 00:24:19,200
COLLABORATION.

659
00:24:19,200 --> 00:24:20,400
I WILL SHOW YOU ON THE NEXT

660
00:24:20,400 --> 00:24:21,560
SLIDE, A LITTLE BIT OF

661
00:24:21,560 --> 00:24:23,240
INFORMATION RELATED TO THAT

662
00:24:23,240 --> 00:24:23,640
PORTFOLIO ANALYSIS.

663
00:24:23,640 --> 00:24:25,400
BUT IN TERMS OF THIS WORKING

664
00:24:25,400 --> 00:24:28,040
GROUP, THEY HAD COMPLETED THE

665
00:24:28,040 --> 00:24:29,400
ANALYSIS, THEY CREATED GUIDING

666
00:24:29,400 --> 00:24:31,840
PRINCIPLES RELATED TO SEX AND

667
00:24:31,840 --> 00:24:32,800
GENDER INFLUENCES IN THE HEALTH

668
00:24:32,800 --> 00:24:36,680
AND WOMEN WHICH WE POSTED ON THE

669
00:24:36,680 --> 00:24:38,560
ORWH OVER THE WEBSITE ON

670
00:24:38,560 --> 00:24:40,800
COVID-19 AND WOMEN, ISSUED AN

671
00:24:40,800 --> 00:24:44,520
RFI RELATED TO THE INTERSECTION

672
00:24:44,520 --> 00:24:46,040
OF SARS-COV-2 INN FEKS AND THE

673
00:24:46,040 --> 00:24:47,800
PANDEMIC AND THE HEALTH OF WOMEN

674
00:24:47,800 --> 00:24:49,120
AND THAT RECENTLY CLOSED AND

675
00:24:49,120 --> 00:24:52,840
CONTRIBUTED TO AN NHLBI LED THAT

676
00:24:52,840 --> 00:24:54,720
ORWH PARTNERED ON LOOKING AT SEX

677
00:24:54,720 --> 00:24:56,680
AND GENDER SPECIFIC COVID-19

678
00:24:56,680 --> 00:24:59,480
OUTCOMES IN HEART, LUNG, BLOOD

679
00:24:59,480 --> 00:25:00,520
AND SLEEP DISORDERS AND WORKING

680
00:25:00,520 --> 00:25:04,000
ON A WHITE PAPER NOW.

681
00:25:04,000 --> 00:25:06,320
HERA'S A HIGH LEVEL OF VIEW OF

682
00:25:06,320 --> 00:25:08,200
THAT PORTFOLIO ANALIS OF OF OVER

683
00:25:08,200 --> 00:25:11,000
A 2 YEAR PERIOD, 540 GRANTS

684
00:25:11,000 --> 00:25:13,760
SUPPORTED BY 21 ICOs HAVE BEEN

685
00:25:13,760 --> 00:25:15,440
ISSUED AND HERE ARE THE MAIN

686
00:25:15,440 --> 00:25:17,600
TOPICS THAT HAVE BEEN COVERED TO

687
00:25:17,600 --> 00:25:19,240
DATE, SO I LOOK FORWARD TO

688
00:25:19,240 --> 00:25:20,160
SHARING MORE OF THIS INFORMATION

689
00:25:20,160 --> 00:25:22,080
WITH YOU AND THERE WAS A

690
00:25:22,080 --> 00:25:24,200
PRESENTATION MADE BY THE CO

691
00:25:24,200 --> 00:25:27,960
CHAIRS OF THIS, WORKING GROUP

692
00:25:27,960 --> 00:25:29,440
AND I WANT TO THANK THEM FOR

693
00:25:29,440 --> 00:25:30,480
THIS WORK AND LOOK FORWARD TO

694
00:25:30,480 --> 00:25:31,400
SHARING MORE OF THAT INFORMATION

695
00:25:31,400 --> 00:25:34,520
WITH YOU IN THE FUTURE.

696
00:25:34,520 --> 00:25:35,960
IN TERMS OF COVID-19 AND THE

697
00:25:35,960 --> 00:25:44,840
HEALTH OF WOMEN, WE RECOGNIZED

698
00:25:44,840 --> 00:25:46,120
EARLY INTERSECTION AND HELP

699
00:25:46,120 --> 00:25:48,040
DEVELOP THE LECTURE SERIES

700
00:25:48,040 --> 00:25:48,560
CALLED DIVERSE VOICES.

701
00:25:48,560 --> 00:25:52,960
IN JULY WE HAD A SESSION ON

702
00:25:52,960 --> 00:25:53,960
COVID-19, AND THEN, IN SEPTEMBER

703
00:25:53,960 --> 00:25:57,480
WE HAVE A SESSION ON VIOLENCE

704
00:25:57,480 --> 00:25:59,480
AND WOMEN, TRAUMA AND ADDICTION,

705
00:25:59,480 --> 00:26:00,880
IMPACTS ON PREGNANT AND

706
00:26:00,880 --> 00:26:01,280
POSTPARTUM PEOPLE.

707
00:26:01,280 --> 00:26:02,600
SO IF YOU MISSED THAT, YOU CAN

708
00:26:02,600 --> 00:26:06,840
GET THAT INFORMATION FROM OUR

709
00:26:06,840 --> 00:26:07,360
WEBSITE.

710
00:26:07,360 --> 00:26:09,560
ONE OF THE ACTIVITIES THAT NIH

711
00:26:09,560 --> 00:26:10,480
HAS UNDERGONE THAT ADDRESSING

712
00:26:10,480 --> 00:26:12,560
SOME OF THE HEALTH INIQUITIES

713
00:26:12,560 --> 00:26:14,600
THAT WERE LAID THERE WITH THE

714
00:26:14,600 --> 00:26:21,480
COVID-19 PANDEMIC INCLUDE A NEW

715
00:26:21,480 --> 00:26:22,120
COMPASS INITIATIVE.

716
00:26:22,120 --> 00:26:24,600
I AM PLEASED TO CO CHAIR THE

717
00:26:24,600 --> 00:26:26,920
COMPASS WORKING GROUP WITH THE

718
00:26:26,920 --> 00:26:29,200
DIRECTORS FROM NIH AND NICHD,

719
00:26:29,200 --> 00:26:32,840
NINR AND THE TRIBAL HEALTH

720
00:26:32,840 --> 00:26:33,200
RESEARCH OFFICE.

721
00:26:33,200 --> 00:26:34,720
SO FOLKS IF THERE'S ANYONE SPEAK

722
00:26:34,720 --> 00:26:36,360
FIGURE THEY COULD MUTE, THAT

723
00:26:36,360 --> 00:26:38,240
WOULD BE GREAT.

724
00:26:38,240 --> 00:26:40,160
COMPASS STANDS FOR COMMUNITY

725
00:26:40,160 --> 00:26:41,120
PARTNERSHIPS TO ADVANCE SCIENCE

726
00:26:41,120 --> 00:26:43,400
FOR SOCIETY.

727
00:26:43,400 --> 00:26:45,840
AND IT'S A COMMON FUND PROGRAM.

728
00:26:45,840 --> 00:26:48,720
THE COMMON FUND ADDRESSES AREAS

729
00:26:48,720 --> 00:26:50,360
THAT CROSS BIOMEDICAL AND

730
00:26:50,360 --> 00:26:51,520
BEHEAEVERRIAL RESEARCH THAT

731
00:26:51,520 --> 00:26:54,240
INVOLVE MULTIPLE NIH INSTITUTES

732
00:26:54,240 --> 00:26:56,640
AND CENTERS AND IS DESIGNED TO

733
00:26:56,640 --> 00:26:57,800
SPUR RESEARCH THAT OTHERWISE

734
00:26:57,800 --> 00:27:02,400
WOULD NOT BE POSSIBLE WITHOUT AN

735
00:27:02,400 --> 00:27:03,800
INITIAL STRATEGIC INVESTMENT.

736
00:27:03,800 --> 00:27:05,840
COMPASS' TRIPLE AIM AND TO

737
00:27:05,840 --> 00:27:07,520
ADVANCE HEALTH EQUITY, IMPROVE

738
00:27:07,520 --> 00:27:09,440
OUTCOMES AND REDUCE DIDIS

739
00:27:09,440 --> 00:27:10,240
PARITIES.

740
00:27:10,240 --> 00:27:12,920
THE PROGRAM GOALS INCLUDE

741
00:27:12,920 --> 00:27:14,720
CATALYZING, DEPLOYING, AND

742
00:27:14,720 --> 00:27:16,240
EVALUATING COMMUNITY LED HEALTH

743
00:27:16,240 --> 00:27:19,040
STRUCTURE AT INTERVENTIONS THAT

744
00:27:19,040 --> 00:27:19,800
EMPLOY MULTISECTOR

745
00:27:19,800 --> 00:27:21,040
PARTNERSHIPPINGS TO REDUCE

746
00:27:21,040 --> 00:27:21,680
HEALTH DISPARITIES.

747
00:27:21,680 --> 00:27:24,160
THE PROGRAM SEEKS TO DEVELOP A

748
00:27:24,160 --> 00:27:26,480
HEALTH EQUITY RESEARCH MODEL FOR

749
00:27:26,480 --> 00:27:27,960
COMMUNITY LET MULTISECTOR

750
00:27:27,960 --> 00:27:29,640
ADVANCE RESEARCH ACROSS NIH

751
00:27:29,640 --> 00:27:32,160
INCLUDING OTHER FEDERAL

752
00:27:32,160 --> 00:27:32,400
AGENCIES.

753
00:27:32,400 --> 00:27:33,840
THERE ARE 2 FUNDING

754
00:27:33,840 --> 00:27:37,240
OPPORTUNITIES THAT HAVE BEEN

755
00:27:37,240 --> 00:27:38,880
RECENTLY LAUNCHED TO KICKOFF

756
00:27:38,880 --> 00:27:41,440
COMPASS, THE COMMUNITY LED

757
00:27:41,440 --> 00:27:42,200
HEALTH STRUCTURAL INTERVENTIONS

758
00:27:42,200 --> 00:27:44,240
INITIATIVE AND THAT WILL BE

759
00:27:44,240 --> 00:27:45,920
USING OTHER TRANSACTIONAL

760
00:27:45,920 --> 00:27:48,080
AUTHORITY AND LETTER OF INTENT

761
00:27:48,080 --> 00:27:49,680
IS DUE FROM COMMUNITY

762
00:27:49,680 --> 00:27:50,360
ORGANIZATIONS ON

763
00:27:50,360 --> 00:27:51,440
NOVEMBER 18th, SO HELP US GET

764
00:27:51,440 --> 00:27:54,080
THE WORD OUT ABOUT THAT AND THE

765
00:27:54,080 --> 00:27:55,680
COMMUNITY PARTNERSHIPS TO

766
00:27:55,680 --> 00:27:56,640
ADVANCE SCIENCE FOR SOCIETY

767
00:27:56,640 --> 00:27:58,640
ACCORD NATION CENTER AND THE RFA

768
00:27:58,640 --> 00:28:01,920
IS RELEASED WITH A DUE DATE OF

769
00:28:01,920 --> 00:28:02,440
JANUARY 27, 2023.

770
00:28:02,440 --> 00:28:04,480
WE HAVE A VARIETY OF RESOURCES

771
00:28:04,480 --> 00:28:09,280
AVAILABLE TO ASSIST YOU.

772
00:28:09,280 --> 00:28:10,400
COUPLE OTHER POLICY AND

773
00:28:10,400 --> 00:28:13,400
SCIENTIFIC UPDATES TO SHARE WITH

774
00:28:13,400 --> 00:28:14,560
YOU.

775
00:28:14,560 --> 00:28:16,240
RECENTLY, NIH UPDATED OUR

776
00:28:16,240 --> 00:28:18,920
INSTRUCTION GUIDE FOR THE RPPR,

777
00:28:18,920 --> 00:28:21,960
OR RESEARCH PERFORMANCE PROGRESS

778
00:28:21,960 --> 00:28:23,360
REPORT.

779
00:28:23,360 --> 00:28:26,040
PER THE NIH REVITALIZATION ACT

780
00:28:26,040 --> 00:28:28,040
OF 1993, AND THE 21st CENTURY

781
00:28:28,040 --> 00:28:32,320
CURES ACT THAT WENT INTO EFFECT

782
00:28:32,320 --> 00:28:33,760
2016, WE REMINDED INDIVIDUALS

783
00:28:33,760 --> 00:28:35,400
THAT RECEIVE NIH FUNDING FOR

784
00:28:35,400 --> 00:28:37,120
PHASE 3 CLINICAL TRIALS THAT

785
00:28:37,120 --> 00:28:40,920
THEY ARE REQUIRED TO REPORT THE

786
00:28:40,920 --> 00:28:42,920
RESULTS OF VALID ANALYSIS BY SEX

787
00:28:42,920 --> 00:28:46,640
OR GENDER RACE AND ETHNICITY FOR

788
00:28:46,640 --> 00:28:47,360
NIH DEFINED PHASE 3 CLINICAL

789
00:28:47,360 --> 00:28:49,040
TRIALS IN THE PROJECT OUTCOMES

790
00:28:49,040 --> 00:28:54,040
SECTION OF THE RPPR AS WELL AS

791
00:28:54,040 --> 00:28:57,280
TO CLINICAL TRIALS .GOV.

792
00:28:57,280 --> 00:28:57,880
THIS INFORMATION WILL BE

793
00:28:57,880 --> 00:28:59,560
AVAILABLE TO THE PUBLIC AND IS

794
00:28:59,560 --> 00:29:00,600
AN IMPORTANT WAY TO GET THIS

795
00:29:00,600 --> 00:29:04,440
INFORMATION OUT TO THE PUBLIC. 

796
00:29:04,440 --> 00:29:07,520
SO PLEASE HELP US DISSEMINATE

797
00:29:07,520 --> 00:29:09,160
THAT TO THE INVESTIGATOR ABOUT

798
00:29:09,160 --> 00:29:10,160
THEIR RESPONSIBILITY TO REPORT

799
00:29:10,160 --> 00:29:11,440
THAT INFORMATION TO NIH PHASE 3

800
00:29:11,440 --> 00:29:15,360
TRIALS IN THE RPPR.

801
00:29:15,360 --> 00:29:16,920
HERE'S THE INFORMATION JUST TO

802
00:29:16,920 --> 00:29:21,440
GIVE YOU EXACTLY WHERE IT IS IN

803
00:29:21,440 --> 00:29:22,960
THE INSTRUCTIONS TO REMIND

804
00:29:22,960 --> 00:29:23,800
INDIVIDUALS ABOUT THIS

805
00:29:23,800 --> 00:29:27,560
REQUIREMENT WITH THE APPROPRIATE

806
00:29:27,560 --> 00:29:27,960
CITATION.

807
00:29:27,960 --> 00:29:29,240
IN TERMS OF POLICY, I'M

808
00:29:29,240 --> 00:29:39,720
PRIVILEGED TO CO SHARE THE NIH

809
00:29:55,280 --> 00:29:55,960
INCLUSION GOVERNANCE COMMITTEE

810
00:29:55,960 --> 00:29:57,600
TD GEFULTS ARE INCLUDED AT VERY

811
00:29:57,600 --> 00:29:59,080
HIGH LEVELS OF GOVERNMENT THAT

812
00:29:59,080 --> 00:30:00,640
JOIN THE INCLUSION GOVERNANCE

813
00:30:00,640 --> 00:30:02,040
COMPLITEE FOR THAT BRIEFING,

814
00:30:02,040 --> 00:30:07,240
THAT BRIEFING, AND THAT REPORT

815
00:30:07,240 --> 00:30:08,400
WAS IN RESPONSE TO A

816
00:30:08,400 --> 00:30:09,280
CONGRESSIONAL CALL FOR THIS

817
00:30:09,280 --> 00:30:10,640
STUDY TO BE CONDUBTED.

818
00:30:10,640 --> 00:30:12,920
CONGRESS ASKED THAT THE NATIONAL

819
00:30:12,920 --> 00:30:14,440
ACADEMIES EXAMINE THE LONG-TERM

820
00:30:14,440 --> 00:30:15,360
MEDICAL AND ECONOMIC IMPACTS OF

821
00:30:15,360 --> 00:30:19,560
A LACK OF INCLUSION OF WOMEN AND

822
00:30:19,560 --> 00:30:20,760
UNDER REPRESENTED MINORITY

823
00:30:20,760 --> 00:30:25,200
GROUPS AND CLINICAL RESEARCH AND

824
00:30:25,200 --> 00:30:27,360
SUBSEQUENT WORK.

825
00:30:27,360 --> 00:30:37,880
THE CHAIR WAS CHAIRED BY

826
00:30:37,880 --> 00:30:38,480
DR. CHRISTEN BIBBINS-DOMINGO.

827
00:30:38,480 --> 00:30:41,640
SOME OF THE STUDY USED THE LOOK

828
00:30:41,640 --> 00:30:48,480
AT THE ELDERLY MODEL, TO LOOK AT

829
00:30:48,480 --> 00:30:58,640
HOW LIFE EXPECTANCY DISPARITIES

830
00:30:58,640 --> 00:30:59,680
IN ELDERLY PEOPLE.

831
00:30:59,680 --> 00:31:02,080
IF DISPARITIES WERE ELIMINATED

832
00:31:02,080 --> 00:31:03,600
DUE TO DIABETES, HEART DISEASE

833
00:31:03,600 --> 00:31:04,320
AND HYPERTENSION.

834
00:31:04,320 --> 00:31:06,440
THEY POSTULATED THAT WITH BETTER

835
00:31:06,440 --> 00:31:07,760
REPRESENTATION IN CLINICAL

836
00:31:07,760 --> 00:31:09,880
RESEARCH, THESE DISPARITIES

837
00:31:09,880 --> 00:31:13,000
COULD BE ELIMINATED AND THEY

838
00:31:13,000 --> 00:31:14,280
ARTICULATED THE ECONOMIC COST OF

839
00:31:14,280 --> 00:31:16,800
THE HEALTH DISPARITIES IN THIS

840
00:31:16,800 --> 00:31:17,040
WAY.

841
00:31:17,040 --> 00:31:19,160
IF ALL LIFE EXPECTANCY

842
00:31:19,160 --> 00:31:20,680
DISPARITIES WERE ELIMINATED FOR

843
00:31:20,680 --> 00:31:22,120
THESE 3 CONDITIONS TOGETHER

844
00:31:22,120 --> 00:31:23,160
COMBINED, DISEASE ISSUES

845
00:31:23,160 --> 00:31:26,600
HYPERTENSION, THE VALUE WOULD BE

846
00:31:26,600 --> 00:31:28,040
$11 TRILLION, THE VALUE FOR EVEN

847
00:31:28,040 --> 00:31:29,600
A MODEST REDUCTION IN HEALTH

848
00:31:29,600 --> 00:31:30,440
DISPARITIES WOULD BE WORTH

849
00:31:30,440 --> 00:31:31,400
BILLIONS OF DOLLARS AND THEY

850
00:31:31,400 --> 00:31:34,400
GIVE AN EXAMPLE THAT IF

851
00:31:34,400 --> 00:31:36,000
1 PERCENT OF LELGT DISPARITIES,

852
00:31:36,000 --> 00:31:38,160
JUST 1 PERCENT WERE ALLEVIATED

853
00:31:38,160 --> 00:31:39,000
BY BETTER REPRESENTATION, IT

854
00:31:39,000 --> 00:31:42,160
WOULD RESULT IN MORE THAN 40

855
00:31:42,160 --> 00:31:43,360
BILLION DOLLARS FOR GAINS IN

856
00:31:43,360 --> 00:31:47,480
DIABETES AND 60 BILLION DOLLARS

857
00:31:47,480 --> 00:31:49,000
FOR HEART DISEASE.

858
00:31:49,000 --> 00:31:50,440
THEY CONCLUDED THAT LARGE SWATHS

859
00:31:50,440 --> 00:31:51,960
OF THE POPULATION, THOSE WHO

860
00:31:51,960 --> 00:31:53,320
FACE THE GREATEST HEALTH

861
00:31:53,320 --> 00:31:55,320
CHALLENGES WERE NOT ADEQUATELY

862
00:31:55,320 --> 00:31:56,960
REPRESENTED IN RESEARCH AND THEY

863
00:31:56,960 --> 00:31:57,720
LOOKED AT CLINICAL RESEARCH

864
00:31:57,720 --> 00:31:59,680
ACROSS THE BOARD THAT IS FUNDED

865
00:31:59,680 --> 00:32:02,840
BY MULTIPLE ENTITIES, THIS WAS A

866
00:32:02,840 --> 00:32:05,920
VERY LARGE SCALE AND SCOPE.

867
00:32:05,920 --> 00:32:07,640
THEY PUT FORWARD, THAT LITTLE

868
00:32:07,640 --> 00:32:10,320
PROGRESS WAS MADE IN THE LAST 3

869
00:32:10,320 --> 00:32:12,240
DECADES, FROM THEIR PERSPECTIVE

870
00:32:12,240 --> 00:32:14,160
TO INCREASE PARTICIPATION AND

871
00:32:14,160 --> 00:32:15,440
RACIAL AND ETHNIC MINORITY,

872
00:32:15,440 --> 00:32:17,440
POPULATION GROUPS AND OTHER

873
00:32:17,440 --> 00:32:18,880
GROUPS LIKE PREGNANT PEOPLE,

874
00:32:18,880 --> 00:32:20,280
OLDER ADULTS, PEOPLE WITH

875
00:32:20,280 --> 00:32:24,320
DISABILITIES AND THAT THE

876
00:32:24,320 --> 00:32:25,480
UNDERREPRESENTATION COMPOUNDS

877
00:32:25,480 --> 00:32:29,080
HEALTH DISPARITIES AND

878
00:32:29,080 --> 00:32:31,040
COMPROMISES THE GENERALIZABILITY

879
00:32:31,040 --> 00:32:31,360
OF RESEARCH.

880
00:32:31,360 --> 00:32:34,280
THEY ALSO PUT FORWARD THAT THE

881
00:32:34,280 --> 00:32:35,600
BENEFITS OF REPRESENTATION WOULD

882
00:32:35,600 --> 00:32:38,240
BE REDUCING HEALTH DISPARITY AND

883
00:32:38,240 --> 00:32:41,120
MORE INNOVATION WITH INCREASED

884
00:32:41,120 --> 00:32:43,440
HETEROGENERATED AITY, AND

885
00:32:43,440 --> 00:32:44,360
EXPANDINGAX ASSESSES AND

886
00:32:44,360 --> 00:32:47,680
INCREASING TRUST IN SCIENCE AND

887
00:32:47,680 --> 00:32:49,000
NEW THERAPIES, THEY HAVE A

888
00:32:49,000 --> 00:32:51,320
VARIETY, A LARGE NUMBER NUMBER

889
00:32:51,320 --> 00:32:52,280
OF RECOMMENDATIONS, I'M ONLY

890
00:32:52,280 --> 00:32:55,880
HIGHLIGHTING A FEW HERE THAT ARE

891
00:32:55,880 --> 00:32:57,320
RELEVANT TO NIH, 1 WAS THE

892
00:32:57,320 --> 00:33:00,200
DEVELOPMENT OF A DHS TASK FORCE,

893
00:33:00,200 --> 00:33:01,800
STANDARDIZATION OF DATA GRAPHIC

894
00:33:01,800 --> 00:33:04,360
AND OTHER ELEMENTS OF CLINICAL

895
00:33:04,360 --> 00:33:09,680
TRIALS .GOV REPORTING

896
00:33:09,680 --> 00:33:10,880
INCORPORATING AND CRITERIA,

897
00:33:10,880 --> 00:33:12,600
DEVELOPING GUIDANCE ON

898
00:33:12,600 --> 00:33:13,680
PARTICIPANT AND CAREGIVER

899
00:33:13,680 --> 00:33:15,720
COMPENSATION AND INVESTING IN

900
00:33:15,720 --> 00:33:16,680
FUNDING COMMUNITY RESEARCH

901
00:33:16,680 --> 00:33:17,040
INFRASTRUCTURE.

902
00:33:17,040 --> 00:33:21,240
SO I DO WANT TO HIGHLIGHT THIS

903
00:33:21,240 --> 00:33:23,360
REPORT FOR YOU AND PROVIDED THAT

904
00:33:23,360 --> 00:33:27,360
URL FOR YOU FOR MORE FOR YOU TO

905
00:33:27,360 --> 00:33:30,600
HAVE MORE DETAILED LOOK @ THAT

906
00:33:30,600 --> 00:33:31,320
NATIONAL ACADEMIES REPORT.

907
00:33:31,320 --> 00:33:33,920
TO JUST SHARE BROAFLY WITH YOU A

908
00:33:33,920 --> 00:33:38,760
RECENT NATURE PUBLICATION THAT

909
00:33:38,760 --> 00:33:40,360
LOOKED ACROSS VEARGS

910
00:33:40,360 --> 00:33:44,240
STAKEHOLDERS WITH VARIOUS

911
00:33:44,240 --> 00:33:45,040
OPINIONS ABOUT SABVAND VARIOUS

912
00:33:45,040 --> 00:33:47,240
EXPERIENCES AND I WILL SHARE 1

913
00:33:47,240 --> 00:33:48,560
QUOTE FROM DR. SUSAN CHENG AND

914
00:33:48,560 --> 00:33:49,440
SHE'S REFERRING TO STUDIES THAT

915
00:33:49,440 --> 00:33:52,040
LOOK AT THE CUT OFFS OF SYSTOLIC

916
00:33:52,040 --> 00:33:53,840
BLOOD PRESSURE BY SEX THAT ARE

917
00:33:53,840 --> 00:33:56,320
ASSOCIATED WITH INCREASED RISK

918
00:33:56,320 --> 00:33:58,240
FOR COMPLICATION, THAT CUT OFF

919
00:33:58,240 --> 00:33:59,440
IS 110-MILLIMETERS OF MERCURY

920
00:33:59,440 --> 00:34:02,280
FOR WOMEN AS A RESULT OF THIS

921
00:34:02,280 --> 00:34:03,640
STUDY, SHE SAID QUOTE FINDINGS

922
00:34:03,640 --> 00:34:06,120
THAT MEN AND WOMEN DIFFER IN

923
00:34:06,120 --> 00:34:08,320
RISK CUT-OFFS WAS ACTUALLY ARY

924
00:34:08,320 --> 00:34:08,800
UEKA MOMENT.

925
00:34:08,800 --> 00:34:10,960
IT WAS LIKE HOW DID WE NOT SEE

926
00:34:10,960 --> 00:34:13,040
THIS BEFORE, SHE ASHES TRIBUTES

927
00:34:13,040 --> 00:34:14,640
THE RESULTS TO THE NE H

928
00:34:14,640 --> 00:34:17,200
CHALLENGE WHICH WAS AN NIH

929
00:34:17,200 --> 00:34:19,240
FUNDING OPPORTUNITY TO LOOK FOR

930
00:34:19,240 --> 00:34:20,200
SEX DIFFERENCES AND SAYS THEY

931
00:34:20,200 --> 00:34:21,160
MADE IT ALL HAPPEN.

932
00:34:21,160 --> 00:34:22,440
OF COURSE THERE ARE MANY

933
00:34:22,440 --> 00:34:23,160
INDIVIDUALS AND STAKEHOLDERS IN

934
00:34:23,160 --> 00:34:25,160
THIS SPACE AND WE RECOGNIZE THE

935
00:34:25,160 --> 00:34:26,600
CONTRIBUTIONS OF SEX DIFFERENCES

936
00:34:26,600 --> 00:34:29,000
RESEARCHERS FOR MANY YEARS AND

937
00:34:29,000 --> 00:34:30,720
OTHER ASSOCIATIONS, PROFESSIONAL

938
00:34:30,720 --> 00:34:34,760
SOCIETIES, AND SCIENTIFIC GROUPS

939
00:34:34,760 --> 00:34:36,720
AND THAT THIS IS A JOURNEY THAT

940
00:34:36,720 --> 00:34:38,520
WE'RE ALL ON TOGETHER TO

941
00:34:38,520 --> 00:34:40,000
IMPRIEWEVER THE APPLICATION OF

942
00:34:40,000 --> 00:34:41,120
SEX AND BIOLOGICAL VARIABLE.

943
00:34:41,120 --> 00:34:43,360
AND FOR OUR SPACE, I'M DELIGHTED

944
00:34:43,360 --> 00:34:45,880
TO SHARE WITH YOU THAT WE

945
00:34:45,880 --> 00:34:49,040
REISSUED THE SPECIALIZED CENTERS

946
00:34:49,040 --> 00:34:50,960
FOR RESEARCH IN EXCELLENCE RFA

947
00:34:50,960 --> 00:34:55,240
EARLIER THIS YEAR, AND WE

948
00:34:55,240 --> 00:34:57,360
RECENTLY GOT A RECEIVE DATE AND

949
00:34:57,360 --> 00:34:59,800
OUR SCORE, NIH'S ONLY CENTER

950
00:34:59,800 --> 00:35:03,480
LEVEL SEX DIFFERENCES FUNDING

951
00:35:03,480 --> 00:35:03,800
OPPORTUNITY.

952
00:35:03,800 --> 00:35:05,920
SO PLEASE STAY TUNED FOR MORE ON

953
00:35:05,920 --> 00:35:08,240
THAT AND VERY RECENTLY WE JUST

954
00:35:08,240 --> 00:35:10,920
REISSUED OUR SEX AND GENDER RO-1

955
00:35:10,920 --> 00:35:13,160
AND NIH'S ONLY RO-1 FOCUSED ON

956
00:35:13,160 --> 00:35:15,160
THE INTERSECTION OF SEX AND

957
00:35:15,160 --> 00:35:16,520
GENDER INFLUENCES ON HEALTH AND

958
00:35:16,520 --> 00:35:17,520
DISEASE, THE FIRST RECEIVE DATE

959
00:35:17,520 --> 00:35:19,520
FOR THAT IS DECEMBER 19th OF

960
00:35:19,520 --> 00:35:20,560
THIS YEAR.

961
00:35:20,560 --> 00:35:23,200
SO WE'RE EXCITED ABOUT THE

962
00:35:23,200 --> 00:35:25,000
CONTINUATION OF THESE AMAZING

963
00:35:25,000 --> 00:35:25,760
PROGRAMS THAT ADDRESS SEX

964
00:35:25,760 --> 00:35:30,160
DIFFERENCES AND WE WANT TO THANK

965
00:35:30,160 --> 00:35:31,040
OUR ICO PARTNERS.

966
00:35:31,040 --> 00:35:36,400
WE HAVE 10 ICs ARE THE SEX AND

967
00:35:36,400 --> 00:35:38,480
GENDER RO-1 AND 8 PARTICIPATING

968
00:35:38,480 --> 00:35:41,880
IN THE SEX AND GENDER STUDIES

969
00:35:41,880 --> 00:35:42,160
ACTIVITIES.

970
00:35:42,160 --> 00:35:44,640
I ALSO WANT TO HIGHLIGHT THE

971
00:35:44,640 --> 00:35:45,360
ANNUAL SCORE MEETING THIS YEAR

972
00:35:45,360 --> 00:35:47,880
AND WE WILL HAVE THE

973
00:35:47,880 --> 00:35:48,560
EN--STRATEGIESITUTE OF GENDER

974
00:35:48,560 --> 00:35:56,440
AND HEALTH DR. KAREN TANNENBAUM,

975
00:35:56,440 --> 00:36:00,320
AND HER KEY NOTE WILL BE NEXT

976
00:36:00,320 --> 00:36:01,760
GENERATION SEX AND GENDER

977
00:36:01,760 --> 00:36:02,080
SCIENCE.

978
00:36:02,080 --> 00:36:03,760
TELL BE AN AMAZING PRESENTATION

979
00:36:03,760 --> 00:36:05,120
AND I'M REALLY LOOKING FORWARD

980
00:36:05,120 --> 00:36:05,400
TO IT.

981
00:36:05,400 --> 00:36:07,840
I WANT TO HEIGHT LIGHT ANOTHER

982
00:36:07,840 --> 00:36:08,800
FUNDING OPPORTUNITY FROM THE

983
00:36:08,800 --> 00:36:10,320
NATIONAL INSTITUTE ON AGING,

984
00:36:10,320 --> 00:36:12,560
THAT'S INVESTIGATING SEX

985
00:36:12,560 --> 00:36:14,440
DIFFERENCES ON MOLECULAR

986
00:36:14,440 --> 00:36:15,280
DETERMINANTS OF ALZHEIMER'S

987
00:36:15,280 --> 00:36:17,560
DISEASE RISK.

988
00:36:17,560 --> 00:36:18,160
THEY'RE SEEKING ININTEGRATIVE

989
00:36:18,160 --> 00:36:19,200
RESEARCH TO UNDERSTAND THE

990
00:36:19,200 --> 00:36:21,440
IMPACT OF SEX DIFFERENCES ON THE

991
00:36:21,440 --> 00:36:22,840
MOLECULAR DETERMINE NATION OF

992
00:36:22,840 --> 00:36:24,160
ALZHEIMER'S DISEASE RISK AND

993
00:36:24,160 --> 00:36:24,880
RESPONSIVENESS TO TREATMENT AND

994
00:36:24,880 --> 00:36:27,640
THEY'RE SPECIFIC LYE LOOKING FOR

995
00:36:27,640 --> 00:36:29,160
APPLICATIONS THAT APPLY CROSS

996
00:36:29,160 --> 00:36:32,480
DISCIPLINEAR COMPETENT TEAM

997
00:36:32,480 --> 00:36:34,680
SCIENCE APPROACHES, GAINING

998
00:36:34,680 --> 00:36:35,440
COMPREHENSIVE MECHANISTIC

999
00:36:35,440 --> 00:36:36,680
UNDERSTANDINGS OF THE IMPACT OF

1000
00:36:36,680 --> 00:36:39,240
SEX DIFFERENCES ON THE MOLECULAR

1001
00:36:39,240 --> 00:36:40,680
TRAJECTORIES OF BRAIN AGING AND

1002
00:36:40,680 --> 00:36:42,600
ON THE PHENOTYPES OF RISK AND

1003
00:36:42,600 --> 00:36:44,240
RESILIENCE AND UNDERLYING

1004
00:36:44,240 --> 00:36:47,320
RESPONSES TO PHARMAICOLOGGIC AND

1005
00:36:47,320 --> 00:36:47,960
NONPHARMAICOLOGGIC INTERVENTIONS

1006
00:36:47,960 --> 00:36:49,280
SOPHISTICATEDY WE KNOW THE SEX

1007
00:36:49,280 --> 00:36:51,600
DIFFERENCES IN ALZHEIMERS HAVE

1008
00:36:51,600 --> 00:36:54,160
BEEN WELL REPORTED AND CONTINUE

1009
00:36:54,160 --> 00:36:56,840
TO BE SOMETHING THAT IS UP FOR

1010
00:36:56,840 --> 00:36:58,200
EXPLOR IEGZ AND TRACTABLE AND WE

1011
00:36:58,200 --> 00:37:01,760
NEED TO EXPABD OUR

1012
00:37:01,760 --> 00:37:02,120
UNDERSTANDING.

1013
00:37:02,120 --> 00:37:04,360
THE EARLIEST SUBMISSION DATE IS

1014
00:37:04,360 --> 00:37:05,720
NOVEMBER 11th SO LET'S GET THE

1015
00:37:05,720 --> 00:37:07,160
WORD OUT ABOUT THIS IMPORTANT

1016
00:37:07,160 --> 00:37:08,640
FUNDING OPPORTUNITY AND I WANT

1017
00:37:08,640 --> 00:37:09,920
TO COMMEND THE NATIONAL

1018
00:37:09,920 --> 00:37:11,320
INSTITUTE ON AGING FOR ISSUING

1019
00:37:11,320 --> 00:37:13,640
THIS SPECIFIC SEX DIFFERENCES

1020
00:37:13,640 --> 00:37:16,240
FOA ON AN IMPORTANT AREA OF

1021
00:37:16,240 --> 00:37:16,720
PUBLIC INFORMATION.

1022
00:37:16,720 --> 00:37:19,040
DO WANT TO UPDATE YOU AS WELL,

1023
00:37:19,040 --> 00:37:19,920
THE NIH DIRECTORS ADVISORY

1024
00:37:19,920 --> 00:37:21,680
COMMITTEE TO THE DIRECTOR

1025
00:37:21,680 --> 00:37:24,200
WORKING GROUP ON ENHANCING RIG

1026
00:37:24,200 --> 00:37:27,840
OR, TRANSPARENCY AND

1027
00:37:27,840 --> 00:37:28,400
TRANSLATABILITY OF ANIMAL

1028
00:37:28,400 --> 00:37:29,760
RESEARCH I HAD THE PRIVILEGE OF

1029
00:37:29,760 --> 00:37:31,280
SERVING ON THAT GROUP AND THEIR

1030
00:37:31,280 --> 00:37:32,440
REPORT HAS BEEN ISSUED.

1031
00:37:32,440 --> 00:37:35,120
THAT REPORT IS SEEKING TO HAVE

1032
00:37:35,120 --> 00:37:37,400
AN OVERALL GOAL TO ALLOW STEAK

1033
00:37:37,400 --> 00:37:39,200
HOLDERS TO HAVE FULL CONFIDENCE

1034
00:37:39,200 --> 00:37:41,040
IN THE QUALITY AND APPLICABILITY

1035
00:37:41,040 --> 00:37:42,160
OF WERE FINDINGS, FROM ANIMAL

1036
00:37:42,160 --> 00:37:45,040
STUDIES AND TO,A SURE THAT

1037
00:37:45,040 --> 00:37:47,080
ANIMAL SUBJECTS ARE USED WITH

1038
00:37:47,080 --> 00:37:48,040
APPROPRIATE CONSIDERATION OF

1039
00:37:48,040 --> 00:37:49,600
ETHICS AND HARM BENEFIT

1040
00:37:49,600 --> 00:37:50,280
ANALYSIS.

1041
00:37:50,280 --> 00:37:52,120
AND THE OVERARCHING GOALS HERE

1042
00:37:52,120 --> 00:37:54,960
AS I MENTIONED ARE IN THE BOTTOM

1043
00:37:54,960 --> 00:37:56,640
LEFT, AND THE REPORT

1044
00:37:56,640 --> 00:37:59,960
RECOMMENDATION HAS 5 THEMES,

1045
00:37:59,960 --> 00:38:02,040
FIRST IMPROVING STUDY DESIGN AND

1046
00:38:02,040 --> 00:38:05,600
ANALYTIC RIGOR OF ANIMAL STUDIES

1047
00:38:05,600 --> 00:38:07,160
BY PROVIDING FOR EXAMPLE

1048
00:38:07,160 --> 00:38:09,720
STATISTICAL TRAINING TO STUDENTS

1049
00:38:09,720 --> 00:38:10,880
AND INVESTIGATORS, FACILITATING

1050
00:38:10,880 --> 00:38:13,560
COLLABORATIONS BETWEEN ANIMAL

1051
00:38:13,560 --> 00:38:14,480
RESEARCHERS AND STATISTICIANS.

1052
00:38:14,480 --> 00:38:17,880
THE SECOND AND ADDRESS BIAS AND

1053
00:38:17,880 --> 00:38:19,840
COMPLETE REPORTING AND

1054
00:38:19,840 --> 00:38:21,200
QUESTIONABLE RESEARCH PRACTICES,

1055
00:38:21,200 --> 00:38:22,160
HERE PERHAPS EXPLORING

1056
00:38:22,160 --> 00:38:23,920
PERSPECTIVE, STUDY PLANS AS

1057
00:38:23,920 --> 00:38:24,520
WELL.

1058
00:38:24,520 --> 00:38:25,240
THIRD IMPROVING THE RELEVANCE

1059
00:38:25,240 --> 00:38:27,520
AND USE OF ANIMAL MODELS, HERE

1060
00:38:27,520 --> 00:38:31,640
IS WHERE SEX COMES IN AND IN

1061
00:38:31,640 --> 00:38:34,720
PARTICULAR, AND ENCOURAGING THE

1062
00:38:34,720 --> 00:38:36,240
USE OF ARRIVE 2.0 IN THE

1063
00:38:36,240 --> 00:38:37,640
ESSENTIAL TECH CHECK LIST,

1064
00:38:37,640 --> 00:38:40,360
IMPROVE METHOD LOGIC AND RESULTS

1065
00:38:40,360 --> 00:38:42,000
REPORTING, AGAIN, SEX COMES IN

1066
00:38:42,000 --> 00:38:44,040
HERE IN TERMS OF SEX SPECIFIC

1067
00:38:44,040 --> 00:38:45,240
RESULTS REPORTING TO ENHANCE

1068
00:38:45,240 --> 00:38:47,120
RIGOR AND TRANSPARENCY AS WELL

1069
00:38:47,120 --> 00:38:50,880
AS TRANSLATABILITY, AND OF

1070
00:38:50,880 --> 00:38:52,040
COURSE, MEASURING AND EVALUATING

1071
00:38:52,040 --> 00:38:57,040
THE EFFECTIVE COST OF THIS WITH

1072
00:38:57,040 --> 00:38:58,080
MANY INTERVENTIONS.

1073
00:38:58,080 --> 00:38:59,400
SO IN REASON STUDY HIGHLIGHTS

1074
00:38:59,400 --> 00:39:00,680
HOW IMPORTANT THIS IS, THIS IS

1075
00:39:00,680 --> 00:39:02,120
IN BRAIN THIS YEAR AND IT SHOWED

1076
00:39:02,120 --> 00:39:03,920
FOR THE FIRST TIME THAT NEURONS

1077
00:39:03,920 --> 00:39:06,080
IN WOMEN'S SPINAL CORD PROCESS

1078
00:39:06,080 --> 00:39:07,240
PAIN DIFFERENTLY FROM MEN.

1079
00:39:07,240 --> 00:39:08,680
SEX DIFFERENCES IN MAIN

1080
00:39:08,680 --> 00:39:10,160
PROCESSING HAVE BEEN REPORTED

1081
00:39:10,160 --> 00:39:13,320
AND WE KNOW OF COURSE THIS IS

1082
00:39:13,320 --> 00:39:16,320
VERY IMPORTANT FOR POTENTIALLY

1083
00:39:16,320 --> 00:39:17,240
IMPROVING SEX AWARE TREATMENTS

1084
00:39:17,240 --> 00:39:22,000
FOR PAIN AND WITH THE ONGOING

1085
00:39:22,000 --> 00:39:24,400
OPIOID EPIDEMIC IN THIS COUNTRY

1086
00:39:24,400 --> 00:39:26,360
THIS IS DOUBLY IMPORTANT WE KNOW

1087
00:39:26,360 --> 00:39:27,720
THAT WOMEN EXPERIENCE PAIN

1088
00:39:27,720 --> 00:39:29,920
DIFFERENTLY MOST OF THE ANIMAL

1089
00:39:29,920 --> 00:39:32,040
RESEARCH RELATED TO PAIN

1090
00:39:32,040 --> 00:39:33,200
INVOLVES MALE RODENTS AND IN

1091
00:39:33,200 --> 00:39:35,600
THIS PARTICULAR STUDY THEY USED

1092
00:39:35,600 --> 00:39:37,880
FEMALE AND MALE FINE

1093
00:39:37,880 --> 00:39:39,040
SALIVA--SALIVA CORD TISSUE

1094
00:39:39,040 --> 00:39:41,320
EXVIVO FROM BOTH RODENTS AND

1095
00:39:41,320 --> 00:39:43,440
HUMANS AND THEY FOWBD THAT BRAIN

1096
00:39:43,440 --> 00:39:45,640
GROWTH FACTOR PLAYS A MAJOR ROLE

1097
00:39:45,640 --> 00:39:47,400
IN AMPLIFYING SPINAL CORD PAIN

1098
00:39:47,400 --> 00:39:49,360
SIGNAL NOTHING BOTH MALE HUMANS

1099
00:39:49,360 --> 00:39:51,600
AND MALE RATS BUT NOT IN FEMALE

1100
00:39:51,600 --> 00:39:55,360
HUMANS OR FEMALE RATS AND WHEN

1101
00:39:55,360 --> 00:39:56,640
FEMALE RATS WERE OVERETC.

1102
00:39:56,640 --> 00:39:58,960
MYSELF, THAT DIFFERENCE

1103
00:39:58,960 --> 00:40:00,360
DISAPPEARS HELPING TO PROVIDE

1104
00:40:00,360 --> 00:40:02,880
INFORMATION FOUNDATION ABOUT THE

1105
00:40:02,880 --> 00:40:03,720
UNDERLYING NECKIMISMS BEHIND SEX

1106
00:40:03,720 --> 00:40:04,960
DIFFERENCES AND PAIN PROCESSING

1107
00:40:04,960 --> 00:40:07,200
AND HIGHLIGHTING THE IMPORTANCE

1108
00:40:07,200 --> 00:40:09,560
OF LOOKING AT ANIMAL MODELS AND

1109
00:40:09,560 --> 00:40:10,520
SEX DIFFERENCES THERE AND HOW

1110
00:40:10,520 --> 00:40:13,440
THEY DO OR DO NOT RECAPITULATE

1111
00:40:13,440 --> 00:40:15,360
SEX DIFFERENCES IN HUMAN

1112
00:40:15,360 --> 00:40:15,840
DISEASE.

1113
00:40:15,840 --> 00:40:17,280
I'M GOING TO SHIFT GEARS HERE TO

1114
00:40:17,280 --> 00:40:21,160
TALK A LITTLE BIT ABOUT SOME

1115
00:40:21,160 --> 00:40:23,200
CLINICAL AND PUBLIC HEALTH

1116
00:40:23,200 --> 00:40:25,040
ISSUES AND I WANT TO BEGENERATED

1117
00:40:25,040 --> 00:40:27,600
BY SHOWING SOME DATA THAT ARE

1118
00:40:27,600 --> 00:40:30,040
VERY DISTURBING TO ME AND THESE

1119
00:40:30,040 --> 00:40:32,440
HIGHLIGHT CHANGES IN FEMALE LIFE

1120
00:40:32,440 --> 00:40:33,960
EXPECTANCY IN THE UNITED STATES

1121
00:40:33,960 --> 00:40:37,360
OVER A 2 YEERD PERIOD VERY

1122
00:40:37,360 --> 00:40:39,360
RECENTLY COMPARED TO HIGH--OTHER

1123
00:40:39,360 --> 00:40:39,880
HIGH INCOME COUNTRIES.

1124
00:40:39,880 --> 00:40:41,080
AND IF YOU LOOK AT THE SLIDE

1125
00:40:41,080 --> 00:40:44,400
HERE, YOU CAN SEE FROM

1126
00:40:44,400 --> 00:40:45,120
NUCLEOTIDES ZEALAND TO THE

1127
00:40:45,120 --> 00:40:46,880
UNITED STATES REDUCTION IN LIFE

1128
00:40:46,880 --> 00:40:47,160
EXPECTANCY.

1129
00:40:47,160 --> 00:40:49,680
THIS IS SCRUOF THE FOR FEMALES,

1130
00:40:49,680 --> 00:40:53,760
THE OVERALL U.S. FEMALE RATE IS

1131
00:40:53,760 --> 00:40:55,360
HERE WITH ALMOST A LITTLE OVER

1132
00:40:55,360 --> 00:40:57,080
BETWEEN 1 AND 2 YEAR REDUCTION

1133
00:40:57,080 --> 00:40:57,680
IN LIFE EXPECTANCY.

1134
00:40:57,680 --> 00:41:03,080
THIS IS ON TOP OF A PREVIOUS

1135
00:41:03,080 --> 00:41:04,680
TREND OF REDUCING LIFE

1136
00:41:04,680 --> 00:41:05,640
EXPECTANCY SLIDES I'VE SHOWN TO

1137
00:41:05,640 --> 00:41:06,840
YOU BEFORE BUT YOU CAN SEE WHEN

1138
00:41:06,840 --> 00:41:09,880
YOU BREAK THIS DOWN BY RACE AND

1139
00:41:09,880 --> 00:41:11,160
ETHNICITY, HISPANIC FEMALES AND

1140
00:41:11,160 --> 00:41:12,880
BLACK FEMALES WITH EVEN LARGER

1141
00:41:12,880 --> 00:41:17,480
REDUCTION IN LIFE EXPECTANCY

1142
00:41:17,480 --> 00:41:19,120
COMPARED TO PEER COUNTRIES HERE.

1143
00:41:19,120 --> 00:41:21,320
SO THAT'S THE BACK DROP FOR

1144
00:41:21,320 --> 00:41:22,720
THESE SLIDES.

1145
00:41:22,720 --> 00:41:25,760
NHLBI FUNDED RESEARCH THAT

1146
00:41:25,760 --> 00:41:28,520
LOOKED AT CARE OF INDIVIDUALS

1147
00:41:28,520 --> 00:41:32,760
EXPERIENCING BOTH ST SEGMENT AND

1148
00:41:32,760 --> 00:41:35,680
NONSTEMI, AND THESE SHOW THE

1149
00:41:35,680 --> 00:41:38,840
PROBABLE OF RECEIVING TIMELY

1150
00:41:38,840 --> 00:41:39,720
ANGIOGRAPHY DURING INDEX

1151
00:41:39,720 --> 00:41:40,000
ADMISSION.

1152
00:41:40,000 --> 00:41:42,880
HERE WITH MALE ANDS WITH

1153
00:41:42,880 --> 00:41:43,240
FEMALES.

1154
00:41:43,240 --> 00:41:45,480
AND WE SEE AN INCREASE IN BOTH

1155
00:41:45,480 --> 00:41:50,360
MALES AND FEMALES RECEIVING

1156
00:41:50,360 --> 00:41:51,720
TIMELY ANGIEOGRAPHY OVER TIME

1157
00:41:51,720 --> 00:41:54,960
FOR BOTH FOR BOTH TYPES OF MI,

1158
00:41:54,960 --> 00:41:56,840
HOWEVER WE SEE A PERSISTENCE GAP

1159
00:41:56,840 --> 00:41:59,360
BETWEEN MALES AND FEMALES.

1160
00:41:59,360 --> 00:42:01,320
WE ALSO SEE PERSISTENT GAP

1161
00:42:01,320 --> 00:42:03,600
BETWEEN WHITE AND OTHER

1162
00:42:03,600 --> 00:42:07,720
POPULATIONS IN TERMS OF

1163
00:42:07,720 --> 00:42:08,920
RECEIVING ANGIEOGRAPHY IN A

1164
00:42:08,920 --> 00:42:09,280
TIMELY MANNER.

1165
00:42:09,280 --> 00:42:11,240
SO ALTHOUGH THERE IS AN

1166
00:42:11,240 --> 00:42:13,040
INCREASING PROPORTION OF

1167
00:42:13,040 --> 00:42:14,280
PATIENTS RECEIVING GUIDELINE

1168
00:42:14,280 --> 00:42:14,880
RECOMMENDED INTERVENTIONS AND

1169
00:42:14,880 --> 00:42:16,920
THERE I WILL SHOW YOU IN THE

1170
00:42:16,920 --> 00:42:18,480
NEXT SLIDE, DECREASED MORTALITY

1171
00:42:18,480 --> 00:42:20,440
OVER THE STUDY PERIOD, WE STILL

1172
00:42:20,440 --> 00:42:23,560
SEE GAPS BY SEX AND RACE AND

1173
00:42:23,560 --> 00:42:23,840
ETHNICITY.

1174
00:42:23,840 --> 00:42:25,560
HERE'S THE SURVIVE AG, THE 1

1175
00:42:25,560 --> 00:42:29,080
YEAR SURVIVAL AND WE DO SEE A

1176
00:42:29,080 --> 00:42:30,800
NARROWING HERE, NOT HERE BUT

1177
00:42:30,800 --> 00:42:35,240
STILL SEE A GAP.

1178
00:42:35,240 --> 00:42:39,240
AND THESE--THIS IS 1 EXAMPLE, A

1179
00:42:39,240 --> 00:42:40,280
CHRONIC DISEASE CARDIOVASCULAR

1180
00:42:40,280 --> 00:42:42,520
CORONARY DISEASE AS 1 EXAMPLE OF

1181
00:42:42,520 --> 00:42:43,360
A CHRONIC DEBILITATING CONDITION

1182
00:42:43,360 --> 00:42:44,560
AND I WILL REMIND YOU THIS IS

1183
00:42:44,560 --> 00:42:47,960
ADDRESSED IN THE WOMEN'S HEALTH

1184
00:42:47,960 --> 00:42:49,280
CONFERENCE REPORT WHERE YOU AS

1185
00:42:49,280 --> 00:42:51,040
THE STAKEHOLDERS THAT SUPPORTED

1186
00:42:51,040 --> 00:42:53,320
AND PARTICIPATED IN THE MEETING

1187
00:42:53,320 --> 00:42:55,960
CALLED FOR A SPECIFIC FRAMEWORK

1188
00:42:55,960 --> 00:42:57,280
TO LOOK AT CHRONIC DISEASE IN

1189
00:42:57,280 --> 00:43:01,240
WOMEN TO BE ABLE TO ADDRESS

1190
00:43:01,240 --> 00:43:02,960
THESE PERSISTENT GAPS.

1191
00:43:02,960 --> 00:43:04,720
HERE'S ANOTHER EXAMPLE OF A

1192
00:43:04,720 --> 00:43:07,360
STUDY THAT LOOKED AT

1193
00:43:07,360 --> 00:43:08,000
RENAL--CHRONIC KIDNEY DISEASE

1194
00:43:08,000 --> 00:43:09,240
AND APPROXIMATE FOUND THAT WOMEN

1195
00:43:09,240 --> 00:43:11,480
WERE LESS LIKELY TO RECEIVE A

1196
00:43:11,480 --> 00:43:13,000
CHRONIC KIDNEY DISEASE

1197
00:43:13,000 --> 00:43:15,080
DIAGNOSTIC CODE, LESS LIKELY TO

1198
00:43:15,080 --> 00:43:17,080
BE REFERRED AND LESS LIKELY TO

1199
00:43:17,080 --> 00:43:23,800
RECEIVE MEDICATION, APPROPRIATE

1200
00:43:23,800 --> 00:43:26,600
MEDICATION FOR EXAMPLE, RASI AND

1201
00:43:26,600 --> 00:43:28,080
STATINS AT THE STUDY AND THEN

1202
00:43:28,080 --> 00:43:29,400
OVERTIME THEY WERE STILL LESS

1203
00:43:29,400 --> 00:43:34,120
LIKELY TO RECEIVE A CKD

1204
00:43:34,120 --> 00:43:36,960
DIAGNOSIS, REFERRED TO A

1205
00:43:36,960 --> 00:43:37,560
NEPHROLOGIST DESPITE ALBUT MIN

1206
00:43:37,560 --> 00:43:40,480
AND LESS LIKELY TO BE MONITORED

1207
00:43:40,480 --> 00:43:45,600
FOR THEIR KRE TINSA TINNINE AND

1208
00:43:45,600 --> 00:43:46,960
ALBIEWMINNURIA LEVELS.

1209
00:43:46,960 --> 00:43:48,520
AND THEY EXPECTING TO FIND SMALL

1210
00:43:48,520 --> 00:43:50,600
OR NO DISPARITIES IN HOW MEN AND

1211
00:43:50,600 --> 00:43:52,360
WOMEN WERE MANAGED BECAUSE

1212
00:43:52,360 --> 00:43:54,120
GUIDELINES DO NOT MAKE

1213
00:43:54,120 --> 00:43:55,640
DISTINCTIONS BY SEX ACCORDING TO

1214
00:43:55,640 --> 00:43:55,840
THEM.

1215
00:43:55,840 --> 00:43:57,880
IN INSTEAD WE OBSERVED PROFOUND

1216
00:43:57,880 --> 00:43:58,880
DIFFERENCES IN THE DETECTION

1217
00:43:58,880 --> 00:44:01,280
WORK UP AND MANAGEMENT OF

1218
00:44:01,280 --> 00:44:03,680
CHRONIC KIDNEY DISEASE

1219
00:44:03,680 --> 00:44:04,600
SUGGESTING SUBOPTIMAL CARE AMONG

1220
00:44:04,600 --> 00:44:05,600
WOMEN.

1221
00:44:05,600 --> 00:44:08,640
SO IN TERMS OF WHAT IT MAY BE

1222
00:44:08,640 --> 00:44:10,280
CRUCIATING TO THE DATA, IN

1223
00:44:10,280 --> 00:44:12,720
ADDITION TO COVID-19 IN TERMS OF

1224
00:44:12,720 --> 00:44:13,800
THE LIFE EXPECTANCY DATA I

1225
00:44:13,800 --> 00:44:15,560
SHOWED YOU, OF COURSE THE

1226
00:44:15,560 --> 00:44:17,240
COVID-19 PANDEMIC IS A CRITICAL

1227
00:44:17,240 --> 00:44:18,280
CONTRIBUTOR BUT WE ALSO HAVE TO

1228
00:44:18,280 --> 00:44:19,800
LOOK AT THESE OTHER FACTORS AND

1229
00:44:19,800 --> 00:44:22,480
I WILL END THIS LITTLE SECTION

1230
00:44:22,480 --> 00:44:24,120
WITH AN NICHD FUNDED STUDY THAT

1231
00:44:24,120 --> 00:44:28,080
LOOKED AT USING THE NURSES

1232
00:44:28,080 --> 00:44:29,600
HEALTH STUDY OVER 110,000 NURSES

1233
00:44:29,600 --> 00:44:32,520
FOLLOWED OVER 28 YEARS TO SEE

1234
00:44:32,520 --> 00:44:34,080
WHO GOT, AND IN HERE THEY WERE

1235
00:44:34,080 --> 00:44:34,880
LOOKING AT EN--STRATEGIES DENSE

1236
00:44:34,880 --> 00:44:37,640
OF STROKE AND THEY FOUND

1237
00:44:37,640 --> 00:44:40,360
INDIVIDUALS THAT HAD

1238
00:44:40,360 --> 00:44:41,040
LAPROSCOPICLY CONFIRMED

1239
00:44:41,040 --> 00:44:42,200
ENDOMETRIOSIS HAD A 34%

1240
00:44:42,200 --> 00:44:44,440
INCREASED RISK OF INCIDENCE

1241
00:44:44,440 --> 00:44:46,360
STROKE WHILE THE ABSOLUTE RISK

1242
00:44:46,360 --> 00:44:49,040
OF STROKE WAS SMALL, THIS IS AN

1243
00:44:49,040 --> 00:44:51,600
IMPORTANT SIGNAL SHOWING THAT

1244
00:44:51,600 --> 00:44:52,320
ENDOMETRIOSIS MAY INFLUENCE RISK

1245
00:44:52,320 --> 00:44:59,160
THROUGH A VARIETY OF FACTORS,

1246
00:44:59,160 --> 00:45:00,440
THROUGH ENDOGENOUS INFLAMMATION,

1247
00:45:00,440 --> 00:45:02,800
HORMONAL OR THE CONSEQUENCES OF

1248
00:45:02,800 --> 00:45:03,960
THE STREEMENT OF ENDOMETRIOSIS

1249
00:45:03,960 --> 00:45:05,480
AND THAT INFORMATION'S

1250
00:45:05,480 --> 00:45:06,400
HIGHLIGHTED HERE.

1251
00:45:06,400 --> 00:45:10,000
WE KNOW THAT HYPERTENSION, HIGH

1252
00:45:10,000 --> 00:45:13,280
CHOLESTEROL LEVELS, HORMONE

1253
00:45:13,280 --> 00:45:14,760
THERAPY USE, HYSTERECTOMY, AND

1254
00:45:14,760 --> 00:45:17,600
NEFF RECTIFIED ME WHICH SEVERAL

1255
00:45:17,600 --> 00:45:18,400
INDIVIDUALS WITH ENDOMETRIOSIS

1256
00:45:18,400 --> 00:45:20,040
HAVE AND THEY ARE ALSO

1257
00:45:20,040 --> 00:45:20,960
ASSOCIATED WITH STROKE RISK, SO

1258
00:45:20,960 --> 00:45:23,120
THIS IS A COMP LITLICATED

1259
00:45:23,120 --> 00:45:24,680
PICTURE BUT WE DO HIGHLIGHT THE

1260
00:45:24,680 --> 00:45:28,760
IMPORTANCE OF CONSIDERING FEMALE

1261
00:45:28,760 --> 00:45:30,280
SPECIFIC CARDIOVASCULAR RISKS

1262
00:45:30,280 --> 00:45:32,520
LIKE PREGNANCY INDUCED

1263
00:45:32,520 --> 00:45:36,000
HYPERTENSION, LIKE ENDOMETRIOSIS

1264
00:45:36,000 --> 00:45:37,880
AS WE THINK ABOUT CHRONIC

1265
00:45:37,880 --> 00:45:38,280
DISEASE DEVELOPMENT.

1266
00:45:38,280 --> 00:45:39,560
ONE OF THE WAYS WE ARE SEEKING

1267
00:45:39,560 --> 00:45:44,560
TO ADDRESS THESE CHALLENGES IS

1268
00:45:44,560 --> 00:45:45,320
TO GALVANIZE HEALTH EQUITY

1269
00:45:45,320 --> 00:45:46,880
THROUGH EDUCATION APPROXIMATE -

1270
00:45:46,880 --> 00:45:48,520
WE RECENTLY ANNOUNCED OUR NEW

1271
00:45:48,520 --> 00:45:50,960
GENDER 25, IT STANDS FOR

1272
00:45:50,960 --> 00:45:51,760
GALVANIZING HEALTH EQUITY

1273
00:45:51,760 --> 00:45:58,440
THROUGH NOVARTISET AND DIVERSE

1274
00:45:58,440 --> 00:45:59,760
EDUCATIONAL RESOURCES AND WOO

1275
00:45:59,760 --> 00:46:01,960
INTEND WITH THIS SEX RELATED

1276
00:46:01,960 --> 00:46:03,240
ACTIVITIES THAT COMPLEMENT OR

1277
00:46:03,240 --> 00:46:10,680
ENHANCE TRAINING OF A DIVERSE

1278
00:46:10,680 --> 00:46:13,480
WORKFORCE AND WE ARE LOOKING FOR

1279
00:46:13,480 --> 00:46:14,840
SKILLS DEVELOPMENT, CURRICULA,

1280
00:46:14,840 --> 00:46:16,120
METHODS DEVELOPMENT, WE ARE

1281
00:46:16,120 --> 00:46:17,760
THRILLED TO HAVE SO MANY

1282
00:46:17,760 --> 00:46:20,000
PARTNERING WITH US INCLUDING

1283
00:46:20,000 --> 00:46:21,400
SGMRO AND ROUND 1 APPLICATIONS

1284
00:46:21,400 --> 00:46:25,080
ARE DUE IN OCTOBER 27th WOO DO

1285
00:46:25,080 --> 00:46:27,400
WANT TO HIGHLIGHT THAT SEX IS

1286
00:46:27,400 --> 00:46:28,920
THE BIOLOGICAL VARIABLE BUT IT'S

1287
00:46:28,920 --> 00:46:32,920
BASED ON A CLEFT CHAL ROL AND

1288
00:46:32,920 --> 00:46:33,920
ANATOMICAL AND

1289
00:46:33,920 --> 00:46:37,160
PHYSIOLOGICALERATES THAT INCLUDE

1290
00:46:37,160 --> 00:46:42,640
ANATOMY, PHYSIOLOGY, DEN

1291
00:46:42,640 --> 00:46:44,560
GENETICS AND AS WELL AS GENDER

1292
00:46:44,560 --> 00:46:46,640
AND IDENTITY AND FORMS AND POWER

1293
00:46:46,640 --> 00:46:47,840
RELAYINGS AND QUALITY AND EQUITY

1294
00:46:47,840 --> 00:46:49,680
AS A SOCIAL AND CULTURAL

1295
00:46:49,680 --> 00:46:51,240
CONSTRUCT AND HAS MULTIPLE

1296
00:46:51,240 --> 00:46:54,160
DOMAINS, AND SO, BOTH OF THESE

1297
00:46:54,160 --> 00:46:56,280
ARE CRITICALLY IMPORTANT FOR

1298
00:46:56,280 --> 00:46:58,160
HEALTH OUTCOMES FOR PEOPLE AND

1299
00:46:58,160 --> 00:47:00,680
WE WANT TO--WOULD LIKE TO SEE

1300
00:47:00,680 --> 00:47:01,520
MORE RESEARCH THAT INCORPORATES

1301
00:47:01,520 --> 00:47:03,480
THEM AND WE WANT TO SUPPORT THE

1302
00:47:03,480 --> 00:47:06,320
METHODS DEVELOPMENT AND THE

1303
00:47:06,320 --> 00:47:07,000
NECESSARY INFRASTRUCTURE TO SEE

1304
00:47:07,000 --> 00:47:07,920
THAT IN THE FUTURE.

1305
00:47:07,920 --> 00:47:11,160
AND I WANT TO HIGHLIGHT FOR YOU

1306
00:47:11,160 --> 00:47:12,840
OUR LONG STANDING

1307
00:47:12,840 --> 00:47:13,400
INTERPROFESSIONAL HEALTH

1308
00:47:13,400 --> 00:47:14,840
EDUCATION WEBPAGE THAT HOSTS A

1309
00:47:14,840 --> 00:47:19,840
VARIETY OF COURSES THAT WE HAVE

1310
00:47:19,840 --> 00:47:22,720
DEVELOPED OUR BENCH TO BEDSIDE

1311
00:47:22,720 --> 00:47:24,360
FOR HUMAN HEALTH COURSE WAS

1312
00:47:24,360 --> 00:47:25,800
DEVELOPED IN COLLABORATION WITH

1313
00:47:25,800 --> 00:47:27,400
THE FDA'S OFFICE OF WOMEN'S

1314
00:47:27,400 --> 00:47:27,680
HEALTH.

1315
00:47:27,680 --> 00:47:30,360
YOU CAN NOW EARN UP TO 6 CME

1316
00:47:30,360 --> 00:47:31,680
CREDITS FREE, SO TAKE A LOOK AT

1317
00:47:31,680 --> 00:47:32,200
OUR WEBSITE THERE ANY WEB

1318
00:47:32,200 --> 00:47:33,920
CONNECTED HAVE A VARIETY OF

1319
00:47:33,920 --> 00:47:35,800
MATERIALS THAT ARE RELEVANT TO

1320
00:47:35,800 --> 00:47:39,240
ALL LEVELS INCLUDING AN SABB,

1321
00:47:39,240 --> 00:47:40,440
PRIMER AND INTRODUCTORY GUIDE AS

1322
00:47:40,440 --> 00:47:42,200
WELL AND TRAIN THE TRAINER

1323
00:47:42,200 --> 00:47:52,720
MATERIALS ARE NOW INCLUDED.IN

1324
00:47:55,240 --> 00:48:00,160
TERMS OF INFORMATION, CDC

1325
00:48:00,160 --> 00:48:01,560
UPDATED THEIR DATA AND THEY

1326
00:48:01,560 --> 00:48:04,080
FOUND THAT 4 OUT OF 5 U.S.

1327
00:48:04,080 --> 00:48:05,800
PREGNANCY AREYALATED DEATHS ARE

1328
00:48:05,800 --> 00:48:06,880
PREVENTIBLE AND AMONG AMERICAN

1329
00:48:06,880 --> 00:48:10,400
INDIAN OR ALASKA NATIVE PEOPLE,

1330
00:48:10,400 --> 00:48:12,040
93% OF DEATHS ARE PREVENTIBLE.

1331
00:48:12,040 --> 00:48:17,200
THIS IS BASED ON MMRC,

1332
00:48:17,200 --> 00:48:18,400
COMMITTEES FROM 36 STATES.

1333
00:48:18,400 --> 00:48:19,720
THEY REVIEWED DEATHS DURING

1334
00:48:19,720 --> 00:48:20,880
PREGNANCY, DAY OR WEEK OF

1335
00:48:20,880 --> 00:48:22,560
PREGNANCY AND YOU CAN SEE THE

1336
00:48:22,560 --> 00:48:24,440
BREAK DOWN HERE IN TERMS OF

1337
00:48:24,440 --> 00:48:26,160
PROPORTIONS, BUT FROM DAY 7 TO 1

1338
00:48:26,160 --> 00:48:29,040
YEAR OUT OVER HALF OF THESE

1339
00:48:29,040 --> 00:48:29,640
DEATHS OCCUR.

1340
00:48:29,640 --> 00:48:31,680
THEY HIGHLIGHT THE LEADING

1341
00:48:31,680 --> 00:48:33,920
CAUSES, THE LEADING CAUSE NOW IS

1342
00:48:33,920 --> 00:48:36,520
MENTAL HEALTH CONDITIONS

1343
00:48:36,520 --> 00:48:37,720
INCLUDING OVERDOSE AND THEY

1344
00:48:37,720 --> 00:48:40,200
FOUND THAT THE UNDERLYING CAUSES

1345
00:48:40,200 --> 00:48:43,120
VARY BY RACIAL GROUP WITH MENTAL

1346
00:48:43,120 --> 00:48:44,480
HEALTH CONDITIONS, THE LEADING

1347
00:48:44,480 --> 00:48:46,600
CAUSE FOR HISPANIC AND

1348
00:48:46,600 --> 00:48:48,880
NONHISPANIC WHITE WOMEN,

1349
00:48:48,880 --> 00:48:50,400
HEMORRHAGE FOR NONHISPANIC ASIAN

1350
00:48:50,400 --> 00:48:53,320
WOMEN AND HEART CONDITIONS, THE

1351
00:48:53,320 --> 00:48:58,000
LEADING CAUSE FOR NONHISPANIC

1352
00:48:58,000 --> 00:48:58,320
BLACK WOMEN.

1353
00:48:58,320 --> 00:49:00,720
ONE OF THE STEPS AT NIH WE'RE

1354
00:49:00,720 --> 00:49:02,120
TAKING TO ADDRESS THIS IS THE

1355
00:49:02,120 --> 00:49:03,200
PATHWAYS TO PREVENTION PROGRAM.

1356
00:49:03,200 --> 00:49:05,680
THIS 1 IS ENTITLED IDENTIFYING

1357
00:49:05,680 --> 00:49:09,280
RISKS AND INTERVENTIONS TO

1358
00:49:09,280 --> 00:49:09,920
OPTIMIZE POSTPARTUM HEALTH AND

1359
00:49:09,920 --> 00:49:10,960
WE WILL HAVE A WORKSHOP THAT IS

1360
00:49:10,960 --> 00:49:14,800
OPEN TO THE PUBLIC IN NOVEMBER.

1361
00:49:14,800 --> 00:49:16,520
LET SPEAKERS WILL DISCUSS THE

1362
00:49:16,520 --> 00:49:17,920
SCIENTIFIC EVIDENCE AVAILABLE

1363
00:49:17,920 --> 00:49:21,400
FOR PREDICKING OR PREVENTING

1364
00:49:21,400 --> 00:49:22,400
POORER OUTCOMES POSTPARTUM AND

1365
00:49:22,400 --> 00:49:23,360
ATTENDEES WILL HAVE THE

1366
00:49:23,360 --> 00:49:24,240
OPPORTUNITY TO SUBMIT QUESTIONS

1367
00:49:24,240 --> 00:49:26,080
AND COMMENTS AND AFTER THE

1368
00:49:26,080 --> 00:49:27,440
WORKSHOP, AN INDEPENDENT PANEL

1369
00:49:27,440 --> 00:49:30,000
WILL BE DRAFTING A REPORT

1370
00:49:30,000 --> 00:49:31,880
OUTLINING EVIDENCE GAPS AND

1371
00:49:31,880 --> 00:49:33,200
PRYERITYS FOR FUTURE RESEARCH.

1372
00:49:33,200 --> 00:49:34,920
YOU CAN REGISTER FOR THE

1373
00:49:34,920 --> 00:49:36,480
WORKSHOP, SO FAR OVER 5 HELPED

1374
00:49:36,480 --> 00:49:41,200
PEOPLE HAVE REGISTERED FOR THE

1375
00:49:41,200 --> 00:49:41,680
WORKSHOP.

1376
00:49:41,680 --> 00:49:44,200
THE 2 P2 PWORKSHOP QUESTIONS ARE

1377
00:49:44,200 --> 00:49:47,160
@ A BIRTHING PERSON'S ENTRY IS

1378
00:49:47,160 --> 00:49:48,560
INTO PRENATAL CARE WHAT

1379
00:49:48,560 --> 00:49:49,640
COMPLICATIONS OF RISK INDICATORS

1380
00:49:49,640 --> 00:49:53,360
HAVE THE GREATEST RISK IMPACT ON

1381
00:49:53,360 --> 00:49:54,240
POOR POSTPARTUM HEALTH OUTCOMES

1382
00:49:54,240 --> 00:49:56,840
AND TO WHAT EXTENT DO THOSE

1383
00:49:56,840 --> 00:50:07,160
PATTERNS VARY BY RACE AND

1384
00:50:07,160 --> 00:50:07,800
ETHNICITY.

1385
00:50:07,800 --> 00:50:09,880
AND TO WHAT EXTENT DO THEY VARY

1386
00:50:09,880 --> 00:50:12,240
BY RACE AND ETHNICITY AND THE

1387
00:50:12,240 --> 00:50:14,080
INDEPENDENT PANEL INCLUDES THIS

1388
00:50:14,080 --> 00:50:19,000
INPUT, INCLUDING NIH PORTFOLIO

1389
00:50:19,000 --> 00:50:20,560
ANALYSIS, ARK PANEL REPORT TO

1390
00:50:20,560 --> 00:50:21,360
GENERATE THEIR PANEL REPORT.

1391
00:50:21,360 --> 00:50:22,840
I ALSO WANT TO GIVE YOU AN

1392
00:50:22,840 --> 00:50:27,000
UPDATE ON THE NIH IMPROVE

1393
00:50:27,000 --> 00:50:27,720
INITIATIVE.

1394
00:50:27,720 --> 00:50:30,040
AND AN FY22, NIH RECEIVED 30

1395
00:50:30,040 --> 00:50:31,880
BILLION DOLLARS TO EXPAND

1396
00:50:31,880 --> 00:50:32,840
IMPEDIMENTS PROVE INITIATIVE, I

1397
00:50:32,840 --> 00:50:35,800
AM PLEASED TO CO CHAIR ALONG

1398
00:50:35,800 --> 00:50:38,200
WITH DR. DIANEA BI ANCY AND A

1399
00:50:38,200 --> 00:50:42,200
REPRESENTATIVE FROM NIH OD, THE

1400
00:50:42,200 --> 00:50:43,920
NIH PATERNAL MORTALITY TASK

1401
00:50:43,920 --> 00:50:45,320
FORCE THAT HAS OVERSEEN IMPROVE

1402
00:50:45,320 --> 00:50:48,440
TO DATE AND HERE ARE THE FY22

1403
00:50:48,440 --> 00:50:49,960
INITTIAIVE ITS THAT ALL LEAD TO

1404
00:50:49,960 --> 00:50:52,600
A NEW PROGRAM ON MATERNAL HEALTH

1405
00:50:52,600 --> 00:50:53,200
CENTERS OF EXCELLENCE.

1406
00:50:53,200 --> 00:50:59,000
THIS YEAR WE FUNDED AWARDS FOR

1407
00:50:59,000 --> 00:51:00,000
PATIENT IMPLEMENTATION NOSI,

1408
00:51:00,000 --> 00:51:01,800
SEEKING TO GENERATE EVIDENCE

1409
00:51:01,800 --> 00:51:03,760
BASED FINDINGS WITH EMPHASIS ON

1410
00:51:03,760 --> 00:51:05,040
STRATEGIES TO TEST EVIDENCE

1411
00:51:05,040 --> 00:51:06,800
BASED FINDINGS FOR EMPHASIS ON

1412
00:51:06,800 --> 00:51:09,200
STRATEGIES FOR POPULATIONS WITH

1413
00:51:09,200 --> 00:51:12,680
HEALTH DISPARITIES, COMMUNITY

1414
00:51:12,680 --> 00:51:14,280
PARTNERSHIPS CHALLENGE BUILDING

1415
00:51:14,280 --> 00:51:15,320
RESEARCH INFRASTRUCTURE AND

1416
00:51:15,320 --> 00:51:17,960
BARRIERS FOR COMMUNITY AND

1417
00:51:17,960 --> 00:51:18,520
ADVOCACY ORGANIZATIONS

1418
00:51:18,520 --> 00:51:20,760
CONDUCTING MATERNAL HEALTH

1419
00:51:20,760 --> 00:51:22,040
RESEARCH, A RAD-X MATERNAL

1420
00:51:22,040 --> 00:51:23,600
HEALTH CHALLENGE, TRYING TO

1421
00:51:23,600 --> 00:51:26,320
INFOIVATE ON POINT OF CARE AND

1422
00:51:26,320 --> 00:51:29,720
HOME BASED DIAGNOSISTICS THAT

1423
00:51:29,720 --> 00:51:32,840
PREDICT RISK FOR SEVERE MATERNAL

1424
00:51:32,840 --> 00:51:34,800
MORBIDITY AND MORTALITY

1425
00:51:34,800 --> 00:51:35,120
POSTPARTUM.

1426
00:51:35,120 --> 00:51:37,680
CONNECTING TO THE TOP, SEEKING

1427
00:51:37,680 --> 00:51:39,840
TO CONNECT ELECTRONIC HEALTH

1428
00:51:39,840 --> 00:51:41,840
RECORDS RELATING TO MOTHER AND

1429
00:51:41,840 --> 00:51:44,600
INFANT TO ADVANCE THEREFOREY AND

1430
00:51:44,600 --> 00:51:46,480
POSTPARTUM RESEARCH AND A

1431
00:51:46,480 --> 00:51:53,560
COMMUNITY IMPLEMENTATION PROGRAM

1432
00:51:53,560 --> 00:51:56,280
OR CIP FOR COMMUNITY ENGAGED

1433
00:51:56,280 --> 00:52:00,360
IMPLEMENTATION PROJECTS FOR

1434
00:52:00,360 --> 00:52:01,360
EVIDENCE-BASED COMMUNITIES AND

1435
00:52:01,360 --> 00:52:02,560
WHICH ARE INCREASING.

1436
00:52:02,560 --> 00:52:04,320
CENTERS OF EXCELLENCE, THESE ARE

1437
00:52:04,320 --> 00:52:05,720
ALL DESIGNED TO FEED INTO AND

1438
00:52:05,720 --> 00:52:07,280
SUPPORT AND INTEGRATE WITH THE

1439
00:52:07,280 --> 00:52:08,920
CENTERS OF EXCELLENCE FOA THAT

1440
00:52:08,920 --> 00:52:11,800
WE ALSO RELEASED THAT IS

1441
00:52:11,800 --> 00:52:14,120
DESIGNED TO CONDUCT BOTH WIDE

1442
00:52:14,120 --> 00:52:15,120
RANGING ACTIVITIES FROM

1443
00:52:15,120 --> 00:52:16,960
FOUNDATIONAL RESEARCH TO

1444
00:52:16,960 --> 00:52:18,040
IMPLEMENTATION SCIENCE TO

1445
00:52:18,040 --> 00:52:20,800
COMMUNITY PARTNERED RESEARCH TO

1446
00:52:20,800 --> 00:52:22,080
ULTIMATELY REDUCE PREGNANCY

1447
00:52:22,080 --> 00:52:24,080
ASSOCIATED AND PREGNANCY RELATED

1448
00:52:24,080 --> 00:52:27,720
DEATHS IN THE U.S.

1449
00:52:27,720 --> 00:52:31,400
I WANT TO JUST GIVE YOU A QUICK

1450
00:52:31,400 --> 00:52:36,080
SNAPSHOT ON ORWH FUNDING AS I DO

1451
00:52:36,080 --> 00:52:39,400
EACHIER.

1452
00:52:39,400 --> 00:52:39,800
EACH YEAR.

1453
00:52:39,800 --> 00:52:42,720
ON THE LEFT YOU CAN SEE THE

1454
00:52:42,720 --> 00:52:45,040
CURRENT TRENDS AND WE HAVE HAD

1455
00:52:45,040 --> 00:52:45,800
INCREASED FUNDING THAT HAS

1456
00:52:45,800 --> 00:52:47,240
ALLOWED TO US TO EXPAND THE

1457
00:52:47,240 --> 00:52:48,120
PROGRAMS HIGHLIGHTED FOR YOU.

1458
00:52:48,120 --> 00:52:52,200
OT RIGHT IS A BREAK DOWN OF OUR

1459
00:52:52,200 --> 00:52:53,800
RESEARCH PROGRAMS, OUR BIRCH

1460
00:52:53,800 --> 00:52:56,720
PROGRAM, SCORE PROGRAM, NEW

1461
00:52:56,720 --> 00:52:59,320
CAREER PROGRAMS LIKE THE

1462
00:52:59,320 --> 00:53:00,520
CONTINUITY SUPPLEMENTS OR IN

1463
00:53:00,520 --> 00:53:02,200
PREVIOUS PROGRAMS LIKE THE

1464
00:53:02,200 --> 00:53:04,240
REENTRY SUPPLEMENT THAT WAS

1465
00:53:04,240 --> 00:53:07,080
EXPANDED TO INCLUDE

1466
00:53:07,080 --> 00:53:07,800
REINTEGRATION AND SPECIFICALLY

1467
00:53:07,800 --> 00:53:09,560
ADDRESS INDIVIDUALS WHO HAVE

1468
00:53:09,560 --> 00:53:11,840
BEEN AFFECTED BOY UNLAWFUL

1469
00:53:11,840 --> 00:53:13,640
HARASSMENT INCLUDING SEXUAL

1470
00:53:13,640 --> 00:53:15,280
HARASSMENT AND PROVIDES AN

1471
00:53:15,280 --> 00:53:17,400
ONRAMP FOR THEM TO ESCAPE THAT

1472
00:53:17,400 --> 00:53:18,600
ENVIRONMENT.

1473
00:53:18,600 --> 00:53:20,320
OUR U3 PROGRAM, OUR SEX AND

1474
00:53:20,320 --> 00:53:23,160
GENDER RO-1 AND SEX AND GENDER

1475
00:53:23,160 --> 00:53:25,360
ADMIN SUPS AND WE WERE THE ICs

1476
00:53:25,360 --> 00:53:26,360
IN THEIR WOMEN'S HEALTH RESEARCH

1477
00:53:26,360 --> 00:53:26,600
AS WELL.

1478
00:53:26,600 --> 00:53:33,520
SO CAN YOU SEE THE BREAK DOWN

1479
00:53:33,520 --> 00:53:33,720
THERE.

1480
00:53:33,720 --> 00:53:35,480
ASK TO IMIF YOU MORE DETAIL ON

1481
00:53:35,480 --> 00:53:37,560
THE SEXUAL HARASSMENT AREA,

1482
00:53:37,560 --> 00:53:39,280
WE'VE EXPAND OUR ANTIHARASSMENT

1483
00:53:39,280 --> 00:53:41,920
ENFORCEMENT AND IN SECTION 213

1484
00:53:41,920 --> 00:53:44,000
OF THE CONSOLIDATED

1485
00:53:44,000 --> 00:53:44,720
APPROPRIATIONS ACT, WE

1486
00:53:44,720 --> 00:53:49,200
ARTICULATE THAT THE NIH DIRECTOR

1487
00:53:49,200 --> 00:53:50,280
WILL THEREAFTER REQUIRE

1488
00:53:50,280 --> 00:53:51,360
INSTITUTIONS THAT RECEIVE NIH

1489
00:53:51,360 --> 00:53:53,480
FUNDS THROUGH A GRANT OR A

1490
00:53:53,480 --> 00:53:54,640
COOPERATIVE AGREEMENT TO REPORT

1491
00:53:54,640 --> 00:53:56,400
TO NIH WHEN INDIVIDUALS

1492
00:53:56,400 --> 00:53:58,960
IDENTIFIED AS A PI OR AS A KEY

1493
00:53:58,960 --> 00:54:01,400
PERSONNEL, IN AN NIH NOTICE OF

1494
00:54:01,400 --> 00:54:02,800
AWARD ARE REMOVED FROM THEIR

1495
00:54:02,800 --> 00:54:03,640
POSITION OR OTHERWISE

1496
00:54:03,640 --> 00:54:05,880
DISCIPLINED DUE TO CONCERNS

1497
00:54:05,880 --> 00:54:07,360
ABOUT HARASSMENT, BULLYING,

1498
00:54:07,360 --> 00:54:09,720
RETALIATION OR HOSTILE WORK

1499
00:54:09,720 --> 00:54:10,040
CONDITIONS.

1500
00:54:10,040 --> 00:54:12,800
THAT MUST BE REPORTED WNCH 30

1501
00:54:12,800 --> 00:54:15,400
DAYS AND HERE IS A LITTLE BIT OF

1502
00:54:15,400 --> 00:54:16,240
INFORMATION, HERE'S THE GUIDE

1503
00:54:16,240 --> 00:54:18,400
NOTICE IN THE URL FOR THAT,

1504
00:54:18,400 --> 00:54:19,640
FAIRLY RECENTLY THE NATIONAL

1505
00:54:19,640 --> 00:54:21,800
ACADEMIES PUT OUT A NEW REPORT

1506
00:54:21,800 --> 00:54:24,320
ON EXPLORING SAIRVEGZS AND EARLY

1507
00:54:24,320 --> 00:54:25,760
INTERVENTIONS FOR FACULTY SEXUAL

1508
00:54:25,760 --> 00:54:27,720
HARASSMENT AND HIGHER EDUCATION,

1509
00:54:27,720 --> 00:54:30,560
AND THEY PUT FORWARD DATA THAT

1510
00:54:30,560 --> 00:54:33,680
38% OF WOMEN GRADUATE STUDENTS,

1511
00:54:33,680 --> 00:54:35,720
EXPERIENCE SEXUAL HARASSMENT

1512
00:54:35,720 --> 00:54:38,000
FROM FACULTY OR STAFF AND THESE

1513
00:54:38,000 --> 00:54:41,880
CHALLENGES THAT ARE BEING

1514
00:54:41,880 --> 00:54:42,640
EXPERIENCED IN ACADEMIA, INCLUDE

1515
00:54:42,640 --> 00:54:44,520
LACK OF ACCORD NATION AND

1516
00:54:44,520 --> 00:54:45,760
DOCUMMATION AND TRANSPARENCY

1517
00:54:45,760 --> 00:54:47,560
REPORTING AND ACCOUNTABILITY AND

1518
00:54:47,560 --> 00:54:49,200
THEY PERFORM IT ALSO THAT THERE

1519
00:54:49,200 --> 00:54:51,680
WAS NO READILY AVAILABLE GUIDE

1520
00:54:51,680 --> 00:54:53,560
FOR ADMINISTRATORS RELATED TO

1521
00:54:53,560 --> 00:54:54,200
SANCTIONING AND INTERVENING,

1522
00:54:54,200 --> 00:54:57,080
EXCUSE ME, AND CULTURAL RESEARCH

1523
00:54:57,080 --> 00:55:00,720
ON ACCORD NATION AS WELL.

1524
00:55:00,720 --> 00:55:01,800
--ACCORD NATION AS WELL, AND

1525
00:55:01,800 --> 00:55:06,240
THEN I WANT TO HIGHLIGHT 2 NIH

1526
00:55:06,240 --> 00:55:07,400
FUNDED GRANTS IN THIS PLACE.

1527
00:55:07,400 --> 00:55:08,560
WE WERE PLEASED TO COLLABORATE

1528
00:55:08,560 --> 00:55:10,240
WITH THE NATIONAL INSTITUTE OF

1529
00:55:10,240 --> 00:55:12,960
MEDICAL SCIENCES ON THEIR FOA ON

1530
00:55:12,960 --> 00:55:15,240
RESEARCH INTERVENTION THAT

1531
00:55:15,240 --> 00:55:16,880
PROMOTE THE INDIVIDUALS IN THE

1532
00:55:16,880 --> 00:55:19,360
RESEARCH SURPRISE THAT FOA HAS

1533
00:55:19,360 --> 00:55:20,480
SPECIFIC RESEARCH INVITING

1534
00:55:20,480 --> 00:55:21,880
APPLICATIONS RELATED TO

1535
00:55:21,880 --> 00:55:23,200
HARASSMENT AND SEXUAL HARASSMENT

1536
00:55:23,200 --> 00:55:27,600
AND THIS YEAR WE ARE PLEASED TO

1537
00:55:27,600 --> 00:55:32,000
FULLY FUND DR. SALAS'S AWARD AT

1538
00:55:32,000 --> 00:55:36,920
STANFORD AND CO FUND DR. STOCK

1539
00:55:36,920 --> 00:55:40,240
DALE'S AWARD AT INDIANA AT

1540
00:55:40,240 --> 00:55:40,480
PURDUE.

1541
00:55:40,480 --> 00:55:42,560
RIGHT AROUND THE CORNER IS

1542
00:55:42,560 --> 00:55:44,760
ORWH'S FIRST EVER GENDER AND

1543
00:55:44,760 --> 00:55:46,320
HEALTH WORKSHOP ENTITLED THE

1544
00:55:46,320 --> 00:55:48,200
IMPACTS OF STRUCTURAL SEXISM,

1545
00:55:48,200 --> 00:55:49,240
GENDER NORMS, RELAITIONZAL

1546
00:55:49,240 --> 00:55:50,320
POWER, DISCIPLINARY TISSUE AND

1547
00:55:50,320 --> 00:55:52,120
MACROPHAGESSICS AND GENDER

1548
00:55:52,120 --> 00:55:53,160
INEQUALITIES THAT'S ON

1549
00:55:53,160 --> 00:55:54,360
OCTOBER 26, WE HAVE AN ALL STAR

1550
00:55:54,360 --> 00:55:58,000
LINE UP FOR YOU IN TERMS OF OUR

1551
00:55:58,000 --> 00:56:07,720
PLENARY SPEAKERS HEADED BY

1552
00:56:07,720 --> 00:56:10,840
DR. NANCY KREIgE R,

1553
00:56:10,840 --> 00:56:13,840
DR. PATRICIA HOMAN, AND

1554
00:56:13,840 --> 00:56:16,360
DR. VIELKA, AND THEY ARE MANY

1555
00:56:16,360 --> 00:56:17,560
ICO PARTNERS LISTED BELOW, SO

1556
00:56:17,560 --> 00:56:21,080
PLEASE JOIN US THERE, THAT'S

1557
00:56:21,080 --> 00:56:22,120
AVAILABLE BY VIDEOCAST.

1558
00:56:22,120 --> 00:56:24,760
AND OUR SCORE MEETING OUR ANNUAL

1559
00:56:24,760 --> 00:56:26,160
SCORE MEETING IS NOVEMBER 1 WITH

1560
00:56:26,160 --> 00:56:29,680
THE KEY NOTE FROM DR. KAREN

1561
00:56:29,680 --> 00:56:33,360
DENNEN BAM AND OUR ANNUAL BIRCH

1562
00:56:33,360 --> 00:56:35,040
MEETING IS NOVEMBER 2nd AS

1563
00:56:35,040 --> 00:56:37,000
WELL AS OUR LEGACY LEADERSHIP

1564
00:56:37,000 --> 00:56:38,480
LECTURE WITH CATHY HATTER MAN

1565
00:56:38,480 --> 00:56:39,920
AND DR. JUDITH JAMES

1566
00:56:39,920 --> 00:56:40,240
RESPECTIVELY.

1567
00:56:40,240 --> 00:56:41,920
SO PLEASE JOIN US FOR THOSE.

1568
00:56:41,920 --> 00:56:45,120
AND AS I END HERE, I WILL

1569
00:56:45,120 --> 00:56:47,240
HIGHLIGHT THE WAYS THAT YOU CAN

1570
00:56:47,240 --> 00:56:49,920
CONNECT WITH US THROUGH OUR

1571
00:56:49,920 --> 00:56:50,720
QUARTERLY PUBLICATIONS CALLED

1572
00:56:50,720 --> 00:56:52,320
WOMEN'S HEALTH AND FOCUS AT NIH.

1573
00:56:52,320 --> 00:56:53,560
YOU CAN SIGN UP TO RECEIVE

1574
00:56:53,560 --> 00:56:55,320
THOSE, CAN YOU SIGN UP TO A

1575
00:56:55,320 --> 00:56:58,040
MONTHLY E-MAIL, AND TO RECEIVE

1576
00:56:58,040 --> 00:56:59,200
INFORMATION ABOUT OUR EVENTS,

1577
00:56:59,200 --> 00:57:01,400
PLEASE TAKE A ELECTRIC AT OUR

1578
00:57:01,400 --> 00:57:03,800
WOMEN'S SCIENCE AND THE IMPACT

1579
00:57:03,800 --> 00:57:04,800
OF COVID-19 URL, HIGHLIGHTING

1580
00:57:04,800 --> 00:57:06,240
HOW TO FOLLOW US ON SOCIAL

1581
00:57:06,240 --> 00:57:09,440
MEDIA,OT TOP RIGHT HERE AND OUR

1582
00:57:09,440 --> 00:57:09,880
ELEARNING COURSES.

1583
00:57:09,880 --> 00:57:13,040
AND WITH THAT I WILL PAUSE HERE

1584
00:57:13,040 --> 00:57:17,240
AND TAKE A LOOK AND SEE IF WE

1585
00:57:17,240 --> 00:57:20,120
HAVE TIME DR. NOURSI, FOR A FEW

1586
00:57:20,120 --> 00:57:23,280
QUESTIONS, MAYBE 1 QUESTION, I

1587
00:57:23,280 --> 00:57:25,320
HAVE 1 MINUTE BEFORE OUR 10:30.

1588
00:57:25,320 --> 00:57:27,080
DO WE HAVE TIME FOR 1 QUESTION.

1589
00:57:27,080 --> 00:57:28,760
>>YES, WE DO, BEFORE WE
YOU

1590
00:57:28,760 --> 00:57:30,560
TAKE THE QUESTION, I WOULD LIKE

1591
00:57:30,560 --> 00:57:32,520
TO ACKNOWLEDGE DR. CLAYTON IF I

1592
00:57:32,520 --> 00:57:35,240
MAY, 2 MEMBERS WHO JOINED US IN

1593
00:57:35,240 --> 00:57:36,720
BETWEEN, DR. PHIL EPIGENETIC

1594
00:57:36,720 --> 00:57:38,040
SHARPS AND DR. KIM TEMPLE TON.

1595
00:57:38,040 --> 00:57:40,160
THANK YOU FOR JOINING US,

1596
00:57:40,160 --> 00:57:41,000
DR. CHARP'S WE LOOK FORWARD TO

1597
00:57:41,000 --> 00:57:42,760
WORKING WITH YOU FOR THE NEXT

1598
00:57:42,760 --> 00:57:47,240
FEW YEARS AND ALSO DR. CRISWELLS

1599
00:57:47,240 --> 00:57:49,520
NIAMILLIOS DIRECTOR WHO WILL BE

1600
00:57:49,520 --> 00:57:51,160
THE NEXT SPEAKER BUT DR. CLAYTON

1601
00:57:51,160 --> 00:57:53,200
YOU HAVE A FEW MINUTES FOR

1602
00:57:53,200 --> 00:57:53,760
QUESTIONS.

1603
00:57:53,760 --> 00:57:54,080
>>GREAT.

1604
00:57:54,080 --> 00:57:55,440
THANK YOU IF ANYONE WOULD LIKE

1605
00:57:55,440 --> 00:57:57,640
TO UNMUTE OR TURN YOUR VIDEO ON

1606
00:57:57,640 --> 00:58:02,920
TO ASK YOUR QUESTION, THAT WOULD

1607
00:58:02,920 --> 00:58:03,440
BE JUST FINE.

1608
00:58:03,440 --> 00:58:05,320
AND I WILL CHECK THE CHAT AS

1609
00:58:05,320 --> 00:58:06,520
WELL AND I'M SO THRILLED TO HAVE

1610
00:58:06,520 --> 00:58:13,960
YOU ALL HERE WITH ME TODAY.

1611
00:58:13,960 --> 00:58:15,600
>>THERE ARE NO QUESTIONS
IN THE

1612
00:58:15,600 --> 00:58:16,840
CHAT BOX.

1613
00:58:16,840 --> 00:58:18,400
>>WE HAVE DR. CRISWELL
AND IN

1614
00:58:18,400 --> 00:58:19,480
THE INTEREST OF TIME WE WILL GO

1615
00:58:19,480 --> 00:58:21,600
AHEAD AND MOVE ON, WE HAVE 2

1616
00:58:21,600 --> 00:58:24,680
DISCUSSION TIME SLOTS TODAY, A

1617
00:58:24,680 --> 00:58:26,960
MORNING DISCUSSION AND AN

1618
00:58:26,960 --> 00:58:28,480
AFTERNOON DISCUSSION SO I

1619
00:58:28,480 --> 00:58:29,360
WELCOME ECONOMIES AND COMMENTSA

1620
00:58:29,360 --> 00:58:30,640
THE THAT TIME BUT FOR NOW I WANT

1621
00:58:30,640 --> 00:58:34,880
TO GIVE A WARM WELCOME TO

1622
00:58:34,880 --> 00:58:36,080
DR. LINDSAY CRISWELL, OUR NEXT

1623
00:58:36,080 --> 00:58:36,440
PRESENTER.

1624
00:58:36,440 --> 00:58:40,200
SHE BECAME THE DIRECTOR OF NIAMS

1625
00:58:40,200 --> 00:58:41,120
IN FEBRUARY 2021.

1626
00:58:41,120 --> 00:58:42,720
PREVIOUSLY SHE SERVED AS VICE

1627
00:58:42,720 --> 00:58:44,440
CHANCELLOR OF RESEARCH AT THE

1628
00:58:44,440 --> 00:58:46,000
UNIVERSITY OF CALIFORNIA

1629
00:58:46,000 --> 00:58:47,280
SAN FRANCISCO AS WELL PROFESSOR

1630
00:58:47,280 --> 00:58:49,520
OF RHEUMATOLOGY AND ORAL

1631
00:58:49,520 --> 00:58:50,400
APPROXIMATE FACIAL SCIENCES.

1632
00:58:50,400 --> 00:58:51,920
HER RESEARCH FOCUSES ON THE

1633
00:58:51,920 --> 00:58:54,240
GENETICS AND EPIDEMIOLOGY OF

1634
00:58:54,240 --> 00:58:55,360
HUMAN AUTOIMMUNE DISEASES, A

1635
00:58:55,360 --> 00:59:00,320
TOPIC NEAR AND DEAR TO MY HEART

1636
00:59:00,320 --> 00:59:01,320
PARTICULARLY RHEUMATOID

1637
00:59:01,320 --> 00:59:02,560
ARTHRITIS AND [INDISCERNIBLE].

1638
00:59:02,560 --> 00:59:04,320
SHE HAS MENTORED MANY STUDENTS

1639
00:59:04,320 --> 00:59:05,480
TO INDEPENDENT FACULTY TO

1640
00:59:05,480 --> 00:59:08,440
INDEPENDENT RESEARCH CAREERS

1641
00:59:08,440 --> 00:59:09,840
SOMETHING OF UTMOST IMPORTANCE

1642
00:59:09,840 --> 00:59:11,960
TO ORWH AND OUR MISSION.

1643
00:59:11,960 --> 00:59:13,760
SHE RECEIVED BACHELOR'S IN

1644
00:59:13,760 --> 00:59:15,360
IMENETTICS AND MASTERS FROM UC

1645
00:59:15,360 --> 00:59:17,080
BERKELEY AND A DOCTOR OF

1646
00:59:17,080 --> 00:59:18,720
EPIDEMIOLOGY FROM THE

1647
00:59:18,720 --> 00:59:19,600
[INDISCERNIBLE] INSTITUTE FOR

1648
00:59:19,600 --> 00:59:22,000
HEALTH SCIENCES AND ROTTER DAM

1649
00:59:22,000 --> 00:59:24,240
AND HER MEDICAL DEGREE FROM

1650
00:59:24,240 --> 00:59:26,840
UCSF, SO DR. CRISWELL IS BOARD

1651
00:59:26,840 --> 00:59:28,720
CERT TIED IF INTERNAL MEDICINE

1652
00:59:28,720 --> 00:59:31,120
AND RHEUMATOLOGY AND MEMBER OF

1653
00:59:31,120 --> 00:59:32,640
ASSOCIATION AMERICAN PHYSICIANS,

1654
00:59:32,640 --> 00:59:34,680
WELCOME DR. LINDSAY CRISWELL.

1655
00:59:34,680 --> 00:59:37,080
WE ARE SO EXCITED TO HAVE YOU

1656
00:59:37,080 --> 00:59:37,840
WITH US TODAY.

1657
00:59:37,840 --> 00:59:39,680
>>THANK YOU SO MUCH DR.
CLAYTON

1658
00:59:39,680 --> 00:59:40,840
AND IT'S A REAL PLEASURE TO BE

1659
00:59:40,840 --> 00:59:44,400
HERE WITH YOU ALL THIS MORNING.

1660
00:59:44,400 --> 00:59:45,920
SO I APPRECIATE THE OPPORTUNITY

1661
00:59:45,920 --> 00:59:52,920
TO DESCRIBE THE ACCELERATING

1662
00:59:52,920 --> 00:59:53,760
MEDICINE PARTNERSHIP OR AMP AND

1663
00:59:53,760 --> 00:59:56,720
YOU WILL HEAR ME REFER TO THIS

1664
00:59:56,720 --> 00:59:57,400
AS AMP AIM.

1665
00:59:57,400 --> 00:59:59,680
I WANT TO FOCUS BOTHOT EXCITING

1666
00:59:59,680 --> 01:00:00,880
SCIENCE THE PROGRAM SUPPORTS AS

1667
01:00:00,880 --> 01:00:05,640
WELL AS A NEW PARTNERSHIP WITH

1668
01:00:05,640 --> 01:00:05,880
ORWH.

1669
01:00:05,880 --> 01:00:07,080
THAT'S INTENDS AND AIMS TO

1670
01:00:07,080 --> 01:00:09,080
SUPPORT INVESTIGATOR WHO IS WISH

1671
01:00:09,080 --> 01:00:11,080
TO LEVERAGE THE AMP AIM

1672
01:00:11,080 --> 01:00:12,000
INFRASTRUCTURE TO DEVELOP THEIR

1673
01:00:12,000 --> 01:00:13,920
OWN CAREERS IN RESEARCH ON

1674
01:00:13,920 --> 01:00:16,160
IMPORTANT TOPICS AFFECTING

1675
01:00:16,160 --> 01:00:19,240
WOMEN'S HEALTH. 

1676
01:00:19,240 --> 01:00:20,240
NEXT SLIDE, PLEASE.

1677
01:00:20,240 --> 01:00:22,160
SO FOR THOSE NOT FAMILIAR WITH

1678
01:00:22,160 --> 01:00:24,080
AMP, IT'S A PUBLIC PRIVATE

1679
01:00:24,080 --> 01:00:25,600
PARTNERSHIP THAT'S ORGANIZED BY

1680
01:00:25,600 --> 01:00:27,480
THE FOUNDATION FOR THE NIH OR

1681
01:00:27,480 --> 01:00:29,600
FNIH AND IT WAS LAUNCH INDEED

1682
01:00:29,600 --> 01:00:32,480
2014 AND IT CURRENTLY CONSISTS

1683
01:00:32,480 --> 01:00:34,480
OF 9 PROGRAMS, THAT ARE

1684
01:00:34,480 --> 01:00:36,760
SUPPORTED BY 28 INDUSTRY

1685
01:00:36,760 --> 01:00:39,520
PARTNERS, 15 NIH COMPONENTS, AND

1686
01:00:39,520 --> 01:00:42,040
NOW 29 NONPROFIT ORGANIZATIONS.

1687
01:00:42,040 --> 01:00:45,960
AND AS OF JUNE OF THIS YEAR,

1688
01:00:45,960 --> 01:00:47,600
772 MILLION-DOLLAR HAVE BEEN

1689
01:00:47,600 --> 01:00:50,320
INVESTED IN THE PROGRAM.

1690
01:00:50,320 --> 01:00:53,400
THE NEXT SLIDE, SHOWS THE

1691
01:00:53,400 --> 01:00:54,760
IMPORTANT CLINICAL TOPICS THAT

1692
01:00:54,760 --> 01:00:56,880
AMP IS ADDRESSING CURRENTLY.

1693
01:00:56,880 --> 01:01:00,400
THESE INCLUDE ALZHEIMER'S

1694
01:01:00,400 --> 01:01:04,440
DISEASE, TYPE 2 DIABETES, COMMON

1695
01:01:04,440 --> 01:01:05,120
METABOLIC DISORDERS, RHEUMATOID

1696
01:01:05,120 --> 01:01:12,640
ARTHRITIS AND LUNG  RHEUMATOID

1697
01:01:12,640 --> 01:01:16,120
ARTHRITIS AND LUPUS, AS WELL AS

1698
01:01:16,120 --> 01:01:17,080
PARKINSON'S DISEASE,

1699
01:01:17,080 --> 01:01:18,680
SCHIZOPHRENIA, GENE THERAPY FOR

1700
01:01:18,680 --> 01:01:23,200
RARE DISEASES, AND HEART

1701
01:01:23,200 --> 01:01:23,440
FAILURE.

1702
01:01:23,440 --> 01:01:26,600
THE PROJECTS FOCUS ON THE

1703
01:01:26,600 --> 01:01:28,280
PRECOMPETITIVE PHASE AND INCLUDE

1704
01:01:28,280 --> 01:01:31,840
EFFORTS TO IDENTIFY DISEASE

1705
01:01:31,840 --> 01:01:33,000
MECHANISMS, BIOMARKERS DISEASE

1706
01:01:33,000 --> 01:01:35,200
PROGRESSION AND POTENTIAL

1707
01:01:35,200 --> 01:01:35,760
TEARGTS FOR INTERVENTION.

1708
01:01:35,760 --> 01:01:39,240
ON THE NEXT SLIDE, I WANT TO

1709
01:01:39,240 --> 01:01:43,480
PROVIDE A LITTLE HISTORY OF THE

1710
01:01:43,480 --> 01:01:44,640
AMP RHEUMATOID ARTHRITIS IN THE

1711
01:01:44,640 --> 01:01:45,920
[INDISCERNIBLE] PROGRAM WHICH

1712
01:01:45,920 --> 01:01:47,680
WAS THE PRECURSOR TO AMP AIM AND

1713
01:01:47,680 --> 01:01:50,640
I WILL REFER TO RHEUMATOID

1714
01:01:50,640 --> 01:01:53,120
ARTHRITIS AND SYSTEMIC LIEWPUS

1715
01:01:53,120 --> 01:01:54,960
AS R. A. AND FLE.

1716
01:01:54,960 --> 01:01:57,080
SO THIS IS 1 OF THE ORIGINAL

1717
01:01:57,080 --> 01:01:58,760
PROGRAMS LAUNCHED BACK IN 2015

1718
01:01:58,760 --> 01:02:00,120
AND IT FOCUSED ON IDENTIFYING

1719
01:02:00,120 --> 01:02:03,920
THE DISEASE MECH INFORMS FOR R.

1720
01:02:03,920 --> 01:02:05,800
A. AND LUPUS AND CORRECTED AN

1721
01:02:05,800 --> 01:02:06,760
INFRASTRUCTURE FOR COLLECTING

1722
01:02:06,760 --> 01:02:08,400
AND ANALYZING BLOOD AND SYNOVIAL

1723
01:02:08,400 --> 01:02:10,240
TISSUE FROM R. A. PEASHTS AND

1724
01:02:10,240 --> 01:02:12,360
BLOOD URINE, SKIN AND KIDNEY

1725
01:02:12,360 --> 01:02:16,160
TISSUE FROM PATIENTS WITH LUPUS.

1726
01:02:16,160 --> 01:02:17,520
THE INVESTIGATORS WORK TOGETHER

1727
01:02:17,520 --> 01:02:20,000
TO DEVELOP STANDARD OPERATING

1728
01:02:20,000 --> 01:02:21,720
PROCEDURES, TR TISSUE COLLECTION

1729
01:02:21,720 --> 01:02:23,400
AND ANALYSIS AND THEY APPLIED

1730
01:02:23,400 --> 01:02:25,720
SINGLE CELL TECHNOLOGIES TO

1731
01:02:25,720 --> 01:02:27,000
IDENTIFY BIOMARKERS, THERAPEUTIC

1732
01:02:27,000 --> 01:02:28,760
TARGETS AND STRATEGIES FOR THE

1733
01:02:28,760 --> 01:02:31,160
MOLECULAR CLASSIFICATION OF THE

1734
01:02:31,160 --> 01:02:31,360
DISEASE.

1735
01:02:31,360 --> 01:02:34,480
IMPORTANTLY, 1 OF THE MOST

1736
01:02:34,480 --> 01:02:37,360
SIGNIFICANT LEGACIES OF THE AMP

1737
01:02:37,360 --> 01:02:39,520
R. A. LUPUS PROGRAM IS THE RICH

1738
01:02:39,520 --> 01:02:40,640
DATA IT GENERATED AND NOW MADE

1739
01:02:40,640 --> 01:02:42,640
AVAILABLE TO THE BROADER

1740
01:02:42,640 --> 01:02:45,680
RESEARCH COMMUNITY.

1741
01:02:45,680 --> 01:02:47,400
NEXT SLIDE.

1742
01:02:47,400 --> 01:02:50,600
SO WHILE THE AMP R. A. LUPUS

1743
01:02:50,600 --> 01:02:51,600
PROGRAM FOCUSED ON

1744
01:02:51,600 --> 01:02:52,400
DECONSTRUCTION, THAT IS

1745
01:02:52,400 --> 01:02:53,600
IDENTIFYING THE CELL POPULATIONS

1746
01:02:53,600 --> 01:02:56,240
AND PATHWAYS THAT CHARACTERIZE

1747
01:02:56,240 --> 01:02:58,720
THE 2 DISEASES, AMP AIM REFEIGNS

1748
01:02:58,720 --> 01:03:00,040
AND EXTENDS THE SINGLE CELL

1749
01:03:00,040 --> 01:03:02,560
ANALYSIS OF TISSUE, TO

1750
01:03:02,560 --> 01:03:05,440
ADDITIONAL DISEASES, AND IT

1751
01:03:05,440 --> 01:03:06,560
EMPLOYS HIGH DIMENSIONAL MODEL

1752
01:03:06,560 --> 01:03:08,160
ANALYSTICS TO DISCOVER HOW THE

1753
01:03:08,160 --> 01:03:09,480
INNATE AND ADAPTIVE CELLS OF THE

1754
01:03:09,480 --> 01:03:11,240
IMMUNE SYSTEM AND THE TISSUE

1755
01:03:11,240 --> 01:03:14,640
CELLS WORK TOGETHER TO DRIVE

1756
01:03:14,640 --> 01:03:16,280
INFLAMMATION, INJURY, ABNORMAL

1757
01:03:16,280 --> 01:03:21,840
FUNCTION, AND ULTIMATELY

1758
01:03:21,840 --> 01:03:22,560
CLINICAL DISEASE.

1759
01:03:22,560 --> 01:03:25,480
THE NEXT SLIDE SHOWS A BIT MORE

1760
01:03:25,480 --> 01:03:27,080
ABOUT WE EXPECT THIS DISEASE

1761
01:03:27,080 --> 01:03:27,840
RECONSTRUCTION PROCESS TO TELL

1762
01:03:27,840 --> 01:03:29,560
US, THAT IS THE AMP AIM PROGRAM

1763
01:03:29,560 --> 01:03:32,720
THAT WAS JUST RECENTLY LAUNCHED.

1764
01:03:32,720 --> 01:03:34,720
SO NOT ONLY WILL

1765
01:03:34,720 --> 01:03:37,000
INVESTIGATORRING BE STUDYING

1766
01:03:37,000 --> 01:03:37,960
CELL-CELL BEHAVIORIAL

1767
01:03:37,960 --> 01:03:39,760
INTERACTIONS THEYAL ALSO MAP THE

1768
01:03:39,760 --> 01:03:41,000
PHYSICAL INTERACTIONS AND DEFINE

1769
01:03:41,000 --> 01:03:45,640
HOW CELLULAR AND MOLECULAR

1770
01:03:45,640 --> 01:03:48,400
PATHOLOGIES ARE SHARED ACROSS

1771
01:03:48,400 --> 01:03:48,840
DISEASES AND TISSUES.

1772
01:03:48,840 --> 01:03:50,200
THIS KNOWLEDGE WILL ADVANCE OUR

1773
01:03:50,200 --> 01:03:52,720
UNDERSTANDING OF HOW CELL-CELL

1774
01:03:52,720 --> 01:03:54,680
INTERACTIONS ACTIVATE DISEASE

1775
01:03:54,680 --> 01:03:55,520
CAUSING MECHANISMS AND

1776
01:03:55,520 --> 01:03:59,440
ACCELERATE THE DISCOVERY OF NEW

1777
01:03:59,440 --> 01:04:00,360
MEDIATORS OF DISEASES.

1778
01:04:00,360 --> 01:04:02,200
AT A SYSTEMS BIOLOGY LEVEL,

1779
01:04:02,200 --> 01:04:04,640
RESEARCH WILL USE THESE FINDINGS

1780
01:04:04,640 --> 01:04:06,160
AS A FOUNDATION UPON WHICH THEY

1781
01:04:06,160 --> 01:04:08,440
CAN IMPOSSIBLE TO BUILD GREAT

1782
01:04:08,440 --> 01:04:09,880
EPIGENETIC AND GENOMIC STUDIES

1783
01:04:09,880 --> 01:04:12,600
TO IDENTIFY TARGET MOLECULES IN

1784
01:04:12,600 --> 01:04:23,040
DISEASE CAUSING PATHWAYS.

1785
01:04:23,040 --> 01:04:23,640
NEXT SLIDE.

1786
01:04:23,640 --> 01:04:26,440
SO NOT ONLY DOES IT EXPAND THE

1787
01:04:26,440 --> 01:04:31,360
R. A. AND LUPUS STUDIES BUT IT

1788
01:04:31,360 --> 01:04:36,880
ALSO STUDIES SORTING

1789
01:04:36,880 --> 01:04:37,760
SIGNALSIATRIC AND SJOGREN'S

1790
01:04:37,760 --> 01:04:39,640
DISEASE, AND THAT IS

1791
01:04:39,640 --> 01:04:44,120
PARTICULARLY STRIKING FOR LUPUS

1792
01:04:44,120 --> 01:04:44,760
AND SJOGREN'S DISEASE.

1793
01:04:44,760 --> 01:04:47,160
A UNIQUE AIM WILL BE NOT ONLY

1794
01:04:47,160 --> 01:04:48,480
THEY STUDY THESE CONDITIONS

1795
01:04:48,480 --> 01:04:49,840
INDIVIDUALLY BUT THEY WILL ALSO

1796
01:04:49,840 --> 01:04:54,200
STRIVE TO DISCOVER SHARED

1797
01:04:54,200 --> 01:04:54,960
PATHOLOGIC MECHANISMS.

1798
01:04:54,960 --> 01:04:56,800
THE NEXT SLIDE SHOWS AT A VERY

1799
01:04:56,800 --> 01:05:00,560
HIGH LEVEL THE TOOLS AND

1800
01:05:00,560 --> 01:05:02,840
PROCESSES THAT THE 4-AMP AIM

1801
01:05:02,840 --> 01:05:06,520
DISEASE CHAINS, THE 3 SYSTEMS

1802
01:05:06,520 --> 01:05:07,680
BIOLOGY AND TISSUE REPOSITORY

1803
01:05:07,680 --> 01:05:10,200
CORES AND THE 2 TECHNOLOGY CORES

1804
01:05:10,200 --> 01:05:11,160
WE'LL USE.

1805
01:05:11,160 --> 01:05:12,920
THE AWARDS WERE MADE IN MARCH OF

1806
01:05:12,920 --> 01:05:17,960
THIS YEAR AND AT PRESENT

1807
01:05:17,960 --> 01:05:21,560
CONNECTICUT SORTIUM RESEARCHERS

1808
01:05:21,560 --> 01:05:22,640
ARE DEVELOPING THEIR INTEGRATED

1809
01:05:22,640 --> 01:05:22,960
RESEARCH PLAN.

1810
01:05:22,960 --> 01:05:24,400
ON THE OTHER SIDE I WANT TO

1811
01:05:24,400 --> 01:05:25,320
ACKNOWLEDGE THE MANY PARTNERS

1812
01:05:25,320 --> 01:05:31,600
SHOWN ON THIS SLIDE, INCLUDING

1813
01:05:31,600 --> 01:05:33,440
THE NIAID, THE NATIONAL INTUITY

1814
01:05:33,440 --> 01:05:35,720
OF CRANEIO AND DENTAL FACIAL

1815
01:05:35,720 --> 01:05:37,000
RESEARCH, THE NATIONAL EYE

1816
01:05:37,000 --> 01:05:38,200
INSTITUTE AND THE OFFICE OF

1817
01:05:38,200 --> 01:05:39,240
RESEARCH ON WOMEN'S HEALTH.

1818
01:05:39,240 --> 01:05:41,880
SO THESE ARE THE PARTNERS THAT

1819
01:05:41,880 --> 01:05:43,600
ARE SUPPORTING AMP AIM.

1820
01:05:43,600 --> 01:05:46,840
AND THERE'S A BROADER SET OF

1821
01:05:46,840 --> 01:05:48,120
PARTNERS THAT SUPPORTING OTHER

1822
01:05:48,120 --> 01:05:49,880
AMP PROGRAMS AS A MENTIONED AT

1823
01:05:49,880 --> 01:05:50,800
THE OUTSET.

1824
01:05:50,800 --> 01:05:53,240
THE NEXT SLIDE, HIGHLIGHTS THE

1825
01:05:53,240 --> 01:05:57,360
NEW PARTNERSHIP BETWEEN ORWH AND

1826
01:05:57,360 --> 01:05:57,880
NIAIMS.

1827
01:05:57,880 --> 01:05:59,320
DR. CLAYTON AND I ANNOUNCED THIS

1828
01:05:59,320 --> 01:06:02,160
NEW OPPORTUNITY LAST MONTH AT

1829
01:06:02,160 --> 01:06:08,840
THE ACCEPT NIAIMS ADVISORY

1830
01:06:08,840 --> 01:06:09,520
COUNCIL MEETING.

1831
01:06:09,520 --> 01:06:11,480
OUR GOAL IS TO TO DEDICATE WOMEN

1832
01:06:11,480 --> 01:06:12,560
HEALTH RESEARCH BY TRAINING

1833
01:06:12,560 --> 01:06:14,560
INVESTIGATORS IN THE SKILLS OF

1834
01:06:14,560 --> 01:06:17,440
TEAM, SCIENCE, LEADERSHIP AND

1835
01:06:17,440 --> 01:06:17,680
MENTORING.

1836
01:06:17,680 --> 01:06:19,080
LEVERAGING THE INFRASTRUCTURE OF

1837
01:06:19,080 --> 01:06:20,280
THE AMP AIM PROGRAM.

1838
01:06:20,280 --> 01:06:23,720
ONE LESSON LEARNED FROM THE AMP

1839
01:06:23,720 --> 01:06:24,800
R. A. LUPUS PROGRAM IS THE

1840
01:06:24,800 --> 01:06:26,200
IMPORTANCE IT PLAYED IN THE

1841
01:06:26,200 --> 01:06:27,360
CAREERS OF LESS ESTABLISHED

1842
01:06:27,360 --> 01:06:27,600
VRLGTS.

1843
01:06:27,600 --> 01:06:32,040
SO WE WANTED TO CAPITALIZE ON

1844
01:06:32,040 --> 01:06:33,760
RELATED OPPORTUNITIES THWARTED

1845
01:06:33,760 --> 01:06:35,240
BY AMP AIM.

1846
01:06:35,240 --> 01:06:38,880
THE NEXT SLIDE SHOWS OW NIAM'S

1847
01:06:38,880 --> 01:06:40,200
AND SHARED INTEREST IN WOMEN'S

1848
01:06:40,200 --> 01:06:42,480
HEALTH RESEARCH AND CAREER

1849
01:06:42,480 --> 01:06:43,440
DEVELOPMENT INTERSECT TO PROVIDE

1850
01:06:43,440 --> 01:06:44,800
AN ENVIRONMENT WHERE

1851
01:06:44,800 --> 01:06:47,960
INVESTIGATORS CAN GAIN

1852
01:06:47,960 --> 01:06:48,560
LEADERSHIP AND MENTORING

1853
01:06:48,560 --> 01:06:49,880
EXPERIENCE AS WELL AS LEARN TO

1854
01:06:49,880 --> 01:06:51,920
DEAL EFFECTIVELY WITH THE

1855
01:06:51,920 --> 01:06:55,400
COMPLEXITY OF BIG TEAM BASED

1856
01:06:55,400 --> 01:06:55,680
PROJECTS.

1857
01:06:55,680 --> 01:06:58,160
WE ENVISION THIS NEW PROGRAM

1858
01:06:58,160 --> 01:06:58,960
TARGETING MIDCAREER

1859
01:06:58,960 --> 01:07:00,200
INVESTIGATORS WHO AT A CAREER

1860
01:07:00,200 --> 01:07:02,520
STAGE HAD THE POTENTIAL MAKING

1861
01:07:02,520 --> 01:07:03,960
INNOVATIVE DISCOVERIES AND

1862
01:07:03,960 --> 01:07:08,040
CONNECTIONS BETWEEN IDEAS IS

1863
01:07:08,040 --> 01:07:08,400
HIGH.

1864
01:07:08,400 --> 01:07:09,840
I'M HAPPY TO ANNOUNCE THAT SINCE

1865
01:07:09,840 --> 01:07:12,160
THE PROGRAM'S LAUNCH, THE NIH

1866
01:07:12,160 --> 01:07:14,520
OFFICE OF DATA SCIENCE STRATEGY

1867
01:07:14,520 --> 01:07:15,840
HAS ENTHUSIASTICALLY AGREED TO

1868
01:07:15,840 --> 01:07:16,560
CONTRIBUTE FUNDS SOPHISTICATEDY

1869
01:07:16,560 --> 01:07:21,440
THAT WE CAN SUPPORT AN

1870
01:07:21,440 --> 01:07:21,920
ADDITIONAL PARTICIPANT.

1871
01:07:21,920 --> 01:07:24,560
AS SHOWN ON THE NEXT SLIDE, THE

1872
01:07:24,560 --> 01:07:25,840
PROGRAMS OVERALL GOAL IS TO

1873
01:07:25,840 --> 01:07:28,360
DEVELOP A CO SHORT OF WOMEN'S

1874
01:07:28,360 --> 01:07:31,000
HEALTH SCIENTISTS WHO CAN LEAD

1875
01:07:31,000 --> 01:07:32,960
HIGHLY COMPLEX, HIGH IMPACT

1876
01:07:32,960 --> 01:07:34,960
RESEARCH PROGRAMS IN ACADEMIA,

1877
01:07:34,960 --> 01:07:37,800
INDUSTRY, AND THE PUBLIC HEALTH

1878
01:07:37,800 --> 01:07:38,600
SECTORS.

1879
01:07:38,600 --> 01:07:40,000
IT WILL IMPROVE THE HEALTH OF

1880
01:07:40,000 --> 01:07:42,680
WOMEN BY SUPPORTING SCHOLARS WHO

1881
01:07:42,680 --> 01:07:44,400
SPECIALIZE IN WOMEN'S HEALTH

1882
01:07:44,400 --> 01:07:46,080
STUDIES IN AUTOIMMUNITY AND

1883
01:07:46,080 --> 01:07:47,840
IMMUNE RELATED DISEASES AND IN

1884
01:07:47,840 --> 01:07:51,200
RELATED SCIENTIFIC AND CLINICAL

1885
01:07:51,200 --> 01:07:51,440
TOPICS.

1886
01:07:51,440 --> 01:07:53,280
SCHOLARS WILL INTEGRATE THE WORK

1887
01:07:53,280 --> 01:07:54,760
WITH THE AMP AIM NETWORK WITH

1888
01:07:54,760 --> 01:07:55,600
THE SCIENTIFIC GOALS.

1889
01:07:55,600 --> 01:07:58,240
SO THE PROGRESS WILL ADDRESS

1890
01:07:58,240 --> 01:07:59,920
IMPORTANT SCIENTIFIC QUESTIONS

1891
01:07:59,920 --> 01:08:01,320
THAT ENHANCE AMP AIM'S RESEARCH

1892
01:08:01,320 --> 01:08:02,520
AND IMPACT AND THE PROJECT

1893
01:08:02,520 --> 01:08:05,560
SHOULD BENEFIT FROM THE

1894
01:08:05,560 --> 01:08:06,440
INVESTIGATORS INFRASTRUCTURE

1895
01:08:06,440 --> 01:08:08,560
CLINICAL INFORMATION, SAMPLES

1896
01:08:08,560 --> 01:08:09,880
AND DATA THAT AMP AIM IS

1897
01:08:09,880 --> 01:08:13,080
COLLECTING BUT SOME ALSO BRING A

1898
01:08:13,080 --> 01:08:14,000
UNIQUE QUESTION, APPROACH OR

1899
01:08:14,000 --> 01:08:16,520
OPPORTUNITY TO THE AMP AIM

1900
01:08:16,520 --> 01:08:16,800
NETWORK.

1901
01:08:16,800 --> 01:08:19,040
THESE NEW SCIENTIFIC QUESTIONS

1902
01:08:19,040 --> 01:08:21,840
AND,A PROACHS INCLUDING DATA

1903
01:08:21,840 --> 01:08:23,920
SCIENCE OPPORTUNITIES SHOULD

1904
01:08:23,920 --> 01:08:25,720
LEVERAGE AMP AIM INFRASTRUCTURE,

1905
01:08:25,720 --> 01:08:27,640
SAMPLES, COHORTS OR DATA TO

1906
01:08:27,640 --> 01:08:29,360
FURTHER ADVANCE OUTCOMES FOR

1907
01:08:29,360 --> 01:08:31,360
PEOPLE WITH AUTOIMMUNE AND

1908
01:08:31,360 --> 01:08:32,480
IMMUNE MEDIATED DISEASES.

1909
01:08:32,480 --> 01:08:34,280
THE SCHOLARS WILL DEVELOP TEEM

1910
01:08:34,280 --> 01:08:36,560
AND SKILLS SCIENCE THROUGH

1911
01:08:36,560 --> 01:08:37,320
IMMESSIVE CROSS SECTIONAL

1912
01:08:37,320 --> 01:08:38,920
COLLABORATIVE EXPERIENCES TO

1913
01:08:38,920 --> 01:08:41,480
ENABLE THEM TO BYE-BYE EFFECTIVE

1914
01:08:41,480 --> 01:08:42,880
LEADERS OF LARGE CONSORTIA AND

1915
01:08:42,880 --> 01:08:45,400
THEY WILL ENHANCE LEADERSHIP AND

1916
01:08:45,400 --> 01:08:46,800
MENTORSHIP EXPERIENCE BY

1917
01:08:46,800 --> 01:08:48,000
EXPANDING NETWORKS BEYOND THEIR

1918
01:08:48,000 --> 01:08:49,520
CURRENT PLACE OF EMPLOYMENT

1919
01:08:49,520 --> 01:08:51,400
ALLOWING THEM TO SERVE AS

1920
01:08:51,400 --> 01:08:52,600
EFFECTIVE MENTORS FOR FUTURE

1921
01:08:52,600 --> 01:08:53,720
GENERATIONS OF TEAM SCIENTISTS

1922
01:08:53,720 --> 01:08:56,640
WHO ARE FOCUSED ON IMPROVING

1923
01:08:56,640 --> 01:08:57,040
WOMEN'S HEALTH.

1924
01:08:57,040 --> 01:09:01,080
ON THE NEXT SLIDE, SO SOON WE

1925
01:09:01,080 --> 01:09:01,920
WILL INITIATE THE NATIONAL

1926
01:09:01,920 --> 01:09:04,120
SEARCH FOR OUR INITIAL COHORT OF

1927
01:09:04,120 --> 01:09:04,520
SCHOLARS.

1928
01:09:04,520 --> 01:09:07,840
AND WE'RE EXPECTING TO ENROLL 4

1929
01:09:07,840 --> 01:09:09,320
OR 5 SCHOLARS AND SUPPORTING

1930
01:09:09,320 --> 01:09:12,800
THEM FOR A PERIOD OF 2-3 YEARS.

1931
01:09:12,800 --> 01:09:15,920
WE ARE EXTREMELY GRATEFUL TO

1932
01:09:15,920 --> 01:09:18,000
ORWH FOR FUND THANKSGIVING PILOT

1933
01:09:18,000 --> 01:09:21,720
PROJECT AND I ALSO WANT TO

1934
01:09:21,720 --> 01:09:25,080
ACKNOWLEDGE THE WORK OF DR. LISA

1935
01:09:25,080 --> 01:09:27,560
BEG AT ORWH AND

1936
01:09:27,560 --> 01:09:28,160
DR. [INDISCERNIBLE] FOR THEIR

1937
01:09:28,160 --> 01:09:29,240
EFFORTS TO MAKE THIS PROGRAM A

1938
01:09:29,240 --> 01:09:31,800
REALITY AND I'M ALSO GREAT TOFUL

1939
01:09:31,800 --> 01:09:34,080
DR. SUSAN GOOD WHAT WHO IS THE

1940
01:09:34,080 --> 01:09:36,160
DIRECTOR OF ODSS FOR HER

1941
01:09:36,160 --> 01:09:37,800
ENTHUSIASTIC SUPPORT OF THEIR

1942
01:09:37,800 --> 01:09:38,120
PILOT PROGRAM.

1943
01:09:38,120 --> 01:09:39,560
AND ON THE NEXT SLIDE, I WOULD

1944
01:09:39,560 --> 01:09:40,920
LIKE TO THANK YOU ALL FOR YOUR

1945
01:09:40,920 --> 01:09:44,120
INTEREST IN HOW THE NIERK H CAN

1946
01:09:44,120 --> 01:09:45,520
ACCELERATE WOMEN'S HEALTH

1947
01:09:45,520 --> 01:09:47,080
RESEARCH AND ALLOW ALL AMERICANS

1948
01:09:47,080 --> 01:09:49,040
TO BENEFIT FROM OUR NATION'S

1949
01:09:49,040 --> 01:09:49,640
INVESTMENT IN BIOMEDICAL

1950
01:09:49,640 --> 01:09:50,960
RESEARCH AND IF THERE'S TIME, I

1951
01:09:50,960 --> 01:09:56,600
WOULD BE HAPPY TO TAKE ANY

1952
01:09:56,600 --> 01:09:57,000
QUESTIONS.

1953
01:09:57,000 --> 01:10:02,240
>>THANK YOU SO MUCH

1954
01:10:02,240 --> 01:10:03,520
DR. CRISWELL, FOR DESCRIBING

1955
01:10:03,520 --> 01:10:04,160
OWSH EXCITING PARTNERSHIP.

1956
01:10:04,160 --> 01:10:05,920
IT WAS MY DELIGHT FOR JOINING

1957
01:10:05,920 --> 01:10:06,880
YOU AT YOUR COUNSELS AND I WILL

1958
01:10:06,880 --> 01:10:08,720
THANK YOU FOR JOINING ME HERE.

1959
01:10:08,720 --> 01:10:10,480
ARE THERE QUESTIONS FROM THE

1960
01:10:10,480 --> 01:10:13,840
COMMITTEE MEMBERS OR COMMENTS?

1961
01:10:13,840 --> 01:10:16,480
WE LEARNLY WELCOME YOUR

1962
01:10:16,480 --> 01:10:16,720
FEEDBACK.

1963
01:10:16,720 --> 01:10:27,160
--CERTAINLY WELCOME YOUR

1964
01:10:27,840 --> 01:10:28,040
FEEDBACK.

1965
01:10:28,040 --> 01:10:29,200
LET ME GIVE THEM A MOMENT

1966
01:10:29,200 --> 01:10:31,120
BECAUSE THEY ARE NOT SHY.

1967
01:10:31,120 --> 01:10:34,240
IT IS SIGHTING TO SEE THE WORK

1968
01:10:34,240 --> 01:10:37,400
IN THE SJORGREN'S SPACE, IT

1969
01:10:37,400 --> 01:10:38,120
SOMETIMES GETS FORGOTTEN, IT'S

1970
01:10:38,120 --> 01:10:40,640
NOT 1 OF THE BIG AUTOIMMUNE

1971
01:10:40,640 --> 01:10:43,080
DISEASES BUT IT RESULTS IN MUCH

1972
01:10:43,080 --> 01:10:44,000
PAIN DISCOMFORT AND DISABILITY

1973
01:10:44,000 --> 01:10:45,960
AND POOR KAWLT OF LIFE FOR

1974
01:10:45,960 --> 01:10:47,320
INDIVIDUALS THAT ARE AFFECTED.

1975
01:10:47,320 --> 01:10:57,600
LET'S TAKE A LOOK.

1976
01:11:13,760 --> 01:11:14,440
--SUFFERING FROM THIS DISEASE

1977
01:11:14,440 --> 01:11:16,840
AND RESEARCH IN THIS AREA HAS

1978
01:11:16,840 --> 01:11:18,840
REALLY FALLEN BEHIND MANY OTHER

1979
01:11:18,840 --> 01:11:20,480
AUTOIMMUNE DISEASES SO I WAS SO

1980
01:11:20,480 --> 01:11:22,320
PLEASED TO SEE ITS INCLUSION IN

1981
01:11:22,320 --> 01:11:26,760
THIS NEW ITERATION OF THE

1982
01:11:26,760 --> 01:11:27,560
PROGRAM.

1983
01:11:27,560 --> 01:11:27,960
>>ABSOLUTELY.

1984
01:11:27,960 --> 01:11:28,240
ABSOLUTELY.

1985
01:11:28,240 --> 01:11:32,360
MAYBE I WILL JUST ASK A QUESTION

1986
01:11:32,360 --> 01:11:38,200
AS WE MOVE FORWARD HERE

1987
01:11:38,200 --> 01:11:39,400
DR. CRISWELL, YOU HIGHLIGHTED SO

1988
01:11:39,400 --> 01:11:44,120
NICELY THE PARTNERSHIPS THAT ARE

1989
01:11:44,120 --> 01:11:45,840
INTEGRAL TO AMP AND HOW

1990
01:11:45,840 --> 01:11:47,880
IMPORTANT THAT IS, MIGHT YOU

1991
01:11:47,880 --> 01:11:50,800
COMMENT ON KIND OF YOUR

1992
01:11:50,800 --> 01:11:53,600
PERSPECTIVE ON PARTNERSHIPS

1993
01:11:53,600 --> 01:11:54,520
GENERALLY AND HOW WE CAN TAKE

1994
01:11:54,520 --> 01:11:57,720
THEM TO THE NEXT LEVEL TO

1995
01:11:57,720 --> 01:12:00,480
ADVANCE RESEARCH, WHAT ARE YOUR

1996
01:12:00,480 --> 01:12:00,760
THOUGHTS?

1997
01:12:00,760 --> 01:12:03,480
>>YES, I GUESS I WILL
START BY

1998
01:12:03,480 --> 01:12:05,600
SAYING THAT COLLABORATION AND

1999
01:12:05,600 --> 01:12:06,840
ULTIMATELY TEAM SCIENCE HAS BEEN

2000
01:12:06,840 --> 01:12:11,400
A VERY PROMINENT THEME OF MY

2001
01:12:11,400 --> 01:12:12,040
CAREER.

2002
01:12:12,040 --> 01:12:13,560
I THINK INCREASINGLY IN ORDER TO

2003
01:12:13,560 --> 01:12:15,600
ADDRESS THE CHALLENGING PROBLEMS

2004
01:12:15,600 --> 01:12:19,400
THAT WE FACE RELATED TO THE

2005
01:12:19,400 --> 01:12:20,880
HEALTH OF OUR COMMUNITY WE

2006
01:12:20,880 --> 01:12:22,360
ABSOLUTELY HAVE TO FOCUS ON TEAM

2007
01:12:22,360 --> 01:12:23,120
EFFORT AND COLLABORATIVE

2008
01:12:23,120 --> 01:12:23,400
RESEARCH.

2009
01:12:23,400 --> 01:12:25,600
NO 1 PERSON OR TEAM OR

2010
01:12:25,600 --> 01:12:28,720
INSTITUTION HAS ALL OF THE

2011
01:12:28,720 --> 01:12:31,000
REQUISITE IDEAS, RESOURCES, AND

2012
01:12:31,000 --> 01:12:32,160
PEOPLE TO EFFECTIVELY SOLVE

2013
01:12:32,160 --> 01:12:34,200
THESE PROBLEMS AND YOU KNOW THIS

2014
01:12:34,200 --> 01:12:36,080
GOES WELL BEYOND KIND OF

2015
01:12:36,080 --> 01:12:37,320
COLLABORATIONS IN TERMS OF

2016
01:12:37,320 --> 01:12:40,800
DIVERSITY OF SCIENCE, BUT AS YOU

2017
01:12:40,800 --> 01:12:44,400
POINTED OUT, THE PERSPECTIVES

2018
01:12:44,400 --> 01:12:46,360
THAT VOLUNTARY ORGANIZATIONS

2019
01:12:46,360 --> 01:12:47,920
BRING, THAT INDUSTRY PARTNERS

2020
01:12:47,920 --> 01:12:49,160
BRING, THEY PLAY A VERY

2021
01:12:49,160 --> 01:12:53,760
IMPORTANT ROLE IN THE

2022
01:12:53,760 --> 01:12:55,080
DEVELOPMENT OF NEW THERAPIES, OF

2023
01:12:55,080 --> 01:12:56,880
COURSE FOR THE PROBLEMS THAT WE

2024
01:12:56,880 --> 01:12:59,520
FACE, SO, NOW, HAVING SAID THAT,

2025
01:12:59,520 --> 01:13:00,280
THESE PARTNERSHIPS ARE

2026
01:13:00,280 --> 01:13:03,560
COMPLICATED AND THEY CAN BE

2027
01:13:03,560 --> 01:13:05,280
CHALLENGING TO DEVELOP, TO

2028
01:13:05,280 --> 01:13:07,080
COORDINATE, AND TO CONDUCT

2029
01:13:07,080 --> 01:13:10,000
SUCCESSFULLY AND IN THE CASE OF

2030
01:13:10,000 --> 01:13:11,800
AMP WHICH I AM NOW INCREASING LE

2031
01:13:11,800 --> 01:13:13,800
HOLDING UP AS A MODEL AND

2032
01:13:13,800 --> 01:13:16,000
SHINING STAR FOR HOW TO DO

2033
01:13:16,000 --> 01:13:17,560
COLLABORATIVE PUBLIC PRIVATE

2034
01:13:17,560 --> 01:13:19,360
PARTNERSHIP EFFORTS, I THINK THE

2035
01:13:19,360 --> 01:13:20,680
FOUNDATION FOR THE NIH HAS

2036
01:13:20,680 --> 01:13:22,920
PLAYED A CRITICAL ROLE IN YOU

2037
01:13:22,920 --> 01:13:24,000
KNOW BRINGING TOGETHER

2038
01:13:24,000 --> 01:13:26,080
INTERACTING WITH INDUSTRY

2039
01:13:26,080 --> 01:13:28,200
PARTNERS, UNDERSTANDING THEIR

2040
01:13:28,200 --> 01:13:30,920
GOALS, WHAT THEY CAN CONTRIBUTE

2041
01:13:30,920 --> 01:13:32,720
AND CONNECTING THEM WITH VARIOUS

2042
01:13:32,720 --> 01:13:35,240
INSTITUTES AND CENTERS AND

2043
01:13:35,240 --> 01:13:36,200
ACADEMIC INSTITUTIONS AROUND THE

2044
01:13:36,200 --> 01:13:38,560
COUNTRY SO THEY HAVE PLAYED A

2045
01:13:38,560 --> 01:13:42,800
REALLY CRITICAL ROLE IN MAKING

2046
01:13:42,800 --> 01:13:43,760
THIS EFFORT SUCCESSFUL AND THE

2047
01:13:43,760 --> 01:13:45,840
LAST PIECE OF THIS I WOULD LIKE

2048
01:13:45,840 --> 01:13:48,600
TO SHARE IS INCREASINGLY WE'RE

2049
01:13:48,600 --> 01:13:50,520
ALL RECOGNIZING THAT IT'S

2050
01:13:50,520 --> 01:13:52,560
ESSENTIAL TO INCLUDE NOT ONLY

2051
01:13:52,560 --> 01:13:53,520
PATIENT VOLUNTARY ORGANIZATIONS

2052
01:13:53,520 --> 01:13:55,120
BUT THE PATIENTS PERSPECTIVES,

2053
01:13:55,120 --> 01:13:55,880
THE PATIENTS THEMSELVES.

2054
01:13:55,880 --> 01:13:57,800
AND DR. CLAYTON AND OTHERS

2055
01:13:57,800 --> 01:13:59,680
YOU'RE PROBABLY WELL AWARE OF

2056
01:13:59,680 --> 01:14:00,680
THE MANY CONVERSATIONS ACROSS

2057
01:14:00,680 --> 01:14:04,480
THE NIH AND THE COUNTRY ABOUT

2058
01:14:04,480 --> 01:14:06,400
THE IMPORTANCE OF PATIENT

2059
01:14:06,400 --> 01:14:07,880
ENGAINLMENT AND UNDERSTANDING

2060
01:14:07,880 --> 01:14:09,080
THE PATIENT'S PERSPECTIVE AND I

2061
01:14:09,080 --> 01:14:10,680
THINK THAT'S ANOTHER DIMENSION

2062
01:14:10,680 --> 01:14:12,480
AND ELEMENT THAT I'M EAGER TO

2063
01:14:12,480 --> 01:14:14,360
SEE EXPANDED AS PART OF AMP

2064
01:14:14,360 --> 01:14:17,120
PROJECTS AND MORE GENERALLY AS

2065
01:14:17,120 --> 01:14:18,160
WE MOVE FORWARD PLANNING

2066
01:14:18,160 --> 01:14:21,480
RESEARCH TO SOLVE OUR CURRENT

2067
01:14:21,480 --> 01:14:21,760
PROBLEMS.

2068
01:14:21,760 --> 01:14:24,680
>>THANK YOU SO MUCH

2069
01:14:24,680 --> 01:14:26,600
DR. CRISWELL, MAB I WILL TAKE

2070
01:14:26,600 --> 01:14:28,040
ADVANTAGE OF YOU BEING WITH US

2071
01:14:28,040 --> 01:14:31,400
AND ASK MAYBE JUST 1 MORE

2072
01:14:31,400 --> 01:14:32,320
QUESTION ABOUT, IT'S BEEN GREAT

2073
01:14:32,320 --> 01:14:34,320
TO GET TO KNOW YOU AND WE'VE HAD

2074
01:14:34,320 --> 01:14:35,720
OUR CONVERSATIONS ABOUT THE

2075
01:14:35,720 --> 01:14:38,000
FUTURE OF WOMEN'S HEALTH

2076
01:14:38,000 --> 01:14:40,520
RESEARCH IN THE CONTEXT OF

2077
01:14:40,520 --> 01:14:46,640
NIAIMS MISSION AND YOUR VISION

2078
01:14:46,640 --> 01:14:47,800
FOR NIAMS GOING FORWARD AS YOU

2079
01:14:47,800 --> 01:14:50,560
ARE LEADING THIS INSTITUTE GOING

2080
01:14:50,560 --> 01:14:51,800
FORWARD, THERE'S SO MANY

2081
01:14:51,800 --> 01:14:56,120
DISEASES AND CONDITIONS, 

2082
01:14:56,120 --> 01:14:58,320
VIRTUALLY EVERY 1 OF YOUR AREAS

2083
01:14:58,320 --> 01:15:00,560
IS A HEALTH RESEARCH FOR WOMEN'S

2084
01:15:00,560 --> 01:15:00,880
TOPIC.

2085
01:15:00,880 --> 01:15:03,120
HOW DO YOU WOMEN'S HEALTH BEING

2086
01:15:03,120 --> 01:15:04,360
INCORPORATED GOING FORWARD UNDER

2087
01:15:04,360 --> 01:15:05,040
YOUR LEADERSHIP.

2088
01:15:05,040 --> 01:15:07,360
>>WELL, AS YOU POINTED
OUT,

2089
01:15:07,360 --> 01:15:10,520
IT'S A FUNDAMENTAL ASPECT OF OUR

2090
01:15:10,520 --> 01:15:11,360
WORK.

2091
01:15:11,360 --> 01:15:14,440
I MEAN, THE AUTOIMMUNE DISEASES,

2092
01:15:14,440 --> 01:15:16,440
ALMOST WITHOUT EXCEPTION, OTHER

2093
01:15:16,440 --> 01:15:20,360
CONDITIONS SUCH AS

2094
01:15:20,360 --> 01:15:21,440
OSTEOARTHRITIS EXHIBIT, YOU KNOW

2095
01:15:21,440 --> 01:15:27,080
GENDER AND SEX DIFFERENCES THAT

2096
01:15:27,080 --> 01:15:28,280
HAVE BEEN UNDERAPPRECIATED AND

2097
01:15:28,280 --> 01:15:30,480
CERTAINLY NOT FULLY EXPLORED AND

2098
01:15:30,480 --> 01:15:33,960
NOT YET FULLY UNDERSTOOD SO A

2099
01:15:33,960 --> 01:15:35,960
PARTNERSHIP WITH ORWH AND WILL

2100
01:15:35,960 --> 01:15:37,520
BE ABSOLUTELY CRITICAL TO OUR

2101
01:15:37,520 --> 01:15:42,600
SUCCESS AND I'M REALLY DELIGHTED

2102
01:15:42,600 --> 01:15:44,120
THAT YOU KNOW WE CAN LEVERAGE

2103
01:15:44,120 --> 01:15:47,200
THE EFFORTS OF YOUR STRATEGIC

2104
01:15:47,200 --> 01:15:48,840
PROCESS, NOW THAT WE'RE

2105
01:15:48,840 --> 01:15:51,800
INITIATING OURS AND WE

2106
01:15:51,800 --> 01:15:54,160
IDENTIFIED MANY WAYS IN WHICH WE

2107
01:15:54,160 --> 01:15:54,920
INTERSECT AND INCREASING

2108
01:15:54,920 --> 01:15:56,560
LOAMACYY WE SHOULD BE THINKING

2109
01:15:56,560 --> 01:15:59,400
OF EACH OTHER AS VERY

2110
01:15:59,400 --> 01:16:00,400
ENTHUSIASTIC PARTNERS TO HELP

2111
01:16:00,400 --> 01:16:02,040
SUPPORT OUR RESPECTIVE EFFORTS,

2112
01:16:02,040 --> 01:16:03,640
AND WE'RE SO GRATEFUL YOU

2113
01:16:03,640 --> 01:16:04,720
REACHED OUT WITH THIS PARTICULAR

2114
01:16:04,720 --> 01:16:13,120
OPPORTUNITY AND I THINK IT

2115
01:16:13,120 --> 01:16:15,320
ADDRESSES AN UNUSUAL NICHE WHICH

2116
01:16:15,320 --> 01:16:18,040
IS TRAINING WOMEN IN LEADERSHIP

2117
01:16:18,040 --> 01:16:19,640
ROLES IN TEAM SCIENCE, IT'S A

2118
01:16:19,640 --> 01:16:20,920
REALLY IMPORTANT ELEMENT THAT

2119
01:16:20,920 --> 01:16:21,760
HASN'T BEEN SPECIFICALLY

2120
01:16:21,760 --> 01:16:22,760
ADDRESSED BY OTHER PROGRAMS AND

2121
01:16:22,760 --> 01:16:25,960
MORE GENERALLY IN EMERGING ITS

2122
01:16:25,960 --> 01:16:29,160
OF PRIORITIES FOR NIAMS, AND AS

2123
01:16:29,160 --> 01:16:30,600
I SHARED LENIENTLY AT A MEETING

2124
01:16:30,600 --> 01:16:32,080
OF THE INSTITUTE CENTERS AND

2125
01:16:32,080 --> 01:16:34,600
DIRECTORS, I THINK THAT IF WE

2126
01:16:34,600 --> 01:16:38,120
THINK INCREASINGLY ABOUT

2127
01:16:38,120 --> 01:16:42,080
RESEARCH ECOSYSTEMS, THAT ARE BY

2128
01:16:42,080 --> 01:16:46,880
NECESSITY MULTIFACTORIAL WITH

2129
01:16:46,880 --> 01:16:48,360
DIFFERENT PERSPECTIVES,

2130
01:16:48,360 --> 01:16:49,720
SCIENTIFICALLY, DIFFERENT TYPES

2131
01:16:49,720 --> 01:16:53,200
OF DATA FROM OMICS TO SOCIAL

2132
01:16:53,200 --> 01:16:58,960
DETERMINANTS OF HEALTH, TO

2133
01:16:58,960 --> 01:17:00,600
PATIENT REPORTED OUTCOMES,

2134
01:17:00,600 --> 01:17:01,440
DIFFERENT--OR IMPORTANT SYSTEMS

2135
01:17:01,440 --> 01:17:02,480
BIOLOGY PERSPECTIVE WITH EFFORTS

2136
01:17:02,480 --> 01:17:04,440
TO INTEGRATE ALL OF THESE

2137
01:17:04,440 --> 01:17:06,080
DIFFERENT DATA TYPES AND THEN

2138
01:17:06,080 --> 01:17:08,200
IMPORTANTLY MAKE THE DATA

2139
01:17:08,200 --> 01:17:10,240
AVAILABLE TO THE REST OF THE

2140
01:17:10,240 --> 01:17:11,200
RESEARCH COMMUNITY AND ALONG

2141
01:17:11,200 --> 01:17:13,440
THOSE LINES I FULLY SUPPORT THE

2142
01:17:13,440 --> 01:17:16,640
NEW NIH DATA SHARING AND

2143
01:17:16,640 --> 01:17:17,520
MANAGEMENT PLANS WHICH ALTHOUGH,

2144
01:17:17,520 --> 01:17:19,480
YOU KNOW THEY WILL BE

2145
01:17:19,480 --> 01:17:20,480
CHALLENGING AND REQUIRE CULTURAL

2146
01:17:20,480 --> 01:17:24,560
CHANGE IN THE BROADER COMMUNITY

2147
01:17:24,560 --> 01:17:25,920
ABSOLUTELY ESSENTIAL FOR US TO

2148
01:17:25,920 --> 01:17:28,120
MAXIMIZE THE BENEFIT OF OUR

2149
01:17:28,120 --> 01:17:28,920
RESPECTIVE RESEARCH EFFORTS.

2150
01:17:28,920 --> 01:17:30,560
SO I'M FULLY SUPPORTIVE AND THAT

2151
01:17:30,560 --> 01:17:34,120
HAS BEEN AN IMPORTANT GOAL FOR

2152
01:17:34,120 --> 01:17:36,280
THE AMP PROGRAMS SINCE ITS

2153
01:17:36,280 --> 01:17:36,560
INCEPTION.

2154
01:17:36,560 --> 01:17:38,720
IT LOOKS LIKE THERE MAY BE A

2155
01:17:38,720 --> 01:17:39,520
QUESTION HERE.

2156
01:17:39,520 --> 01:17:40,600
>>THERE IS, DR. JONES,
THANK

2157
01:17:40,600 --> 01:17:42,400
YOU SO MUCH FOR BEING WITH US, 1

2158
01:17:42,400 --> 01:17:44,280
OF OUR NEW MEMBERS.

2159
01:17:44,280 --> 01:17:45,640
>>THANK YOU SO MUCH FOR
HAVING

2160
01:17:45,640 --> 01:17:48,120
ME AND THARVEG YOU DR. CRISWELL

2161
01:17:48,120 --> 01:17:50,560
FOR A REALLY GREAT PRESENTATION

2162
01:17:50,560 --> 01:17:51,760
AND INFORMATIVE AND I WAS

2163
01:17:51,760 --> 01:17:54,040
WONDERING IF YOU WOULD CARE TO

2164
01:17:54,040 --> 01:17:56,360
COMMENT ON HOW OR WHAT ARE THE

2165
01:17:56,360 --> 01:17:59,880
EFFORTS TO HELP SCIENTISTS

2166
01:17:59,880 --> 01:18:01,040
TRANSLATE AND COMMUNICATE AND

2167
01:18:01,040 --> 01:18:02,600
EDUCATE OUR POLICY MAKERS

2168
01:18:02,600 --> 01:18:05,520
BECAUSE I KNOW WHEN I WEPT TO

2169
01:18:05,520 --> 01:18:06,880
SCHOOL, NOBODY SHOWED ME HOW TO

2170
01:18:06,880 --> 01:18:09,000
DO THAT AND THAT IS--IT SEEMS TO

2171
01:18:09,000 --> 01:18:11,200
BE MORE AND MORE SO IMPORTANT

2172
01:18:11,200 --> 01:18:15,320
TAKEN--THEY WE ARE COMMUNICATING

2173
01:18:15,320 --> 01:18:17,360
PRACTICAL EVIDENCE-BASED

2174
01:18:17,360 --> 01:18:18,480
TRANSLATABLE EASY TO UNDERSTAND

2175
01:18:18,480 --> 01:18:19,880
FINDINGS FROM OUR RESEARCH.

2176
01:18:19,880 --> 01:18:21,440
SO WOULD LOVE TO HEAR YOUR

2177
01:18:21,440 --> 01:18:22,960
COMMENTS ON THAT.

2178
01:18:22,960 --> 01:18:23,240
THANK YOU.

2179
01:18:23,240 --> 01:18:26,080
>>WOW, I WISH I HAD A
STRAIGHT

2180
01:18:26,080 --> 01:18:27,480
FORWARD ANSWER TO THAT QUESTION,

2181
01:18:27,480 --> 01:18:28,720
THAT'S AN INCREDIBLE LOAMACYY

2182
01:18:28,720 --> 01:18:31,040
IMPORTANT ISSUE AND OF COURSE,

2183
01:18:31,040 --> 01:18:33,960
YOU KNOW SOME OF THE

2184
01:18:33,960 --> 01:18:35,720
COMMUNICATION AND MISCOMMUNE

2185
01:18:35,720 --> 01:18:36,600
KAITIONZ OR MISUNDERSTANDINGS

2186
01:18:36,600 --> 01:18:42,360
THAT WE'RE SO PROMINENT AND

2187
01:18:42,360 --> 01:18:43,680
VISIBLE IN THE CONTEXT OF THE

2188
01:18:43,680 --> 01:18:46,800
LAST 2 YEARS AND THE COVID

2189
01:18:46,800 --> 01:18:47,480
PANDEMIC HIGHLIGHTED HOW

2190
01:18:47,480 --> 01:18:47,960
IMPORTANT THAT IS.

2191
01:18:47,960 --> 01:18:49,200
AND THE FIRST THING I WILL SAY

2192
01:18:49,200 --> 01:18:51,120
ABOUT THAT IS I HOPE THAT WHAT

2193
01:18:51,120 --> 01:18:52,840
WE OBSERVED OVER THE LAST COUPLE

2194
01:18:52,840 --> 01:18:55,800
OF YEARS, DID SNOT DISCOURAGE

2195
01:18:55,800 --> 01:18:58,000
YOUNG PEOPLE FROM PURSUING

2196
01:18:58,000 --> 01:19:01,000
CAREERS IN MEDICINE AND SCIENCE.

2197
01:19:01,000 --> 01:19:04,960
AND SOME OF YOU MAY BE AWARE

2198
01:19:04,960 --> 01:19:07,040
THAT DR. TONY FAUCI, WHO WILL BE

2199
01:19:07,040 --> 01:19:10,920
STEPPING DOWN FROM HIS NIH

2200
01:19:10,920 --> 01:19:12,480
LEADERSHIP ROLES AT THE END OF

2201
01:19:12,480 --> 01:19:13,800
THIS CALENDAR YEAR PLANS TO

2202
01:19:13,800 --> 01:19:17,840
FOCUS O THAT WITH 100% OF HIS

2203
01:19:17,840 --> 01:19:18,720
EFFORT ANDENERGY.

2204
01:19:18,720 --> 01:19:21,440
HE THINK IT'S A VERY IMPORTANT

2205
01:19:21,440 --> 01:19:22,520
AREA TO RESEARCH.

2206
01:19:22,520 --> 01:19:24,280
BUT MOOT ME SAY, THAT'S NOT

2207
01:19:24,280 --> 01:19:25,240
SOMETHING WE RECEIVE TRAINING IN

2208
01:19:25,240 --> 01:19:26,800
AND I THINK THAT'S WHERE

2209
01:19:26,800 --> 01:19:30,360
MENTORING COMES INTO PLAY AND

2210
01:19:30,360 --> 01:19:32,440
IT'S NOT SIMPLY YOUR SINGLE

2211
01:19:32,440 --> 01:19:32,800
PRIMARY MENTOR.

2212
01:19:32,800 --> 01:19:34,160
YOU CAN'T LOOK TO THAT PERSON TO

2213
01:19:34,160 --> 01:19:35,760
PROVIDE ALL OF THESE KIND OF

2214
01:19:35,760 --> 01:19:37,800
LIFE SKILLS THAT WE NEED TO BE

2215
01:19:37,800 --> 01:19:38,760
SUBASSESSESFUL RESEARCHERS AND

2216
01:19:38,760 --> 01:19:40,960
COMMUNICATORS BUT WE NEED TO BE

2217
01:19:40,960 --> 01:19:43,120
THINKING ABOUT MENTORING TEAMS,

2218
01:19:43,120 --> 01:19:45,800
CREATING SUPPORTIVE MENTORING

2219
01:19:45,800 --> 01:19:47,840
ENVIRONMENTS AND THEN LASTLY

2220
01:19:47,840 --> 01:19:50,240
THAT COMMUNICATION FOR THE

2221
01:19:50,240 --> 01:19:52,600
POLICY PIECE.

2222
01:19:52,600 --> 01:19:54,800
THERE IS A PROPOSED NEW COMMON

2223
01:19:54,800 --> 01:19:58,400
FUND EFFORT THAT WILL FOCUS ON

2224
01:19:58,400 --> 01:19:59,440
HEALTH OF INFORMATION

2225
01:19:59,440 --> 01:20:00,760
COMMUNICATION THAT MIGHT TOUCH

2226
01:20:00,760 --> 01:20:06,200
UPON THAT.

2227
01:20:06,200 --> 01:20:07,880
I'M NOT AWARE OF SPECIFIC PLANS

2228
01:20:07,880 --> 01:20:09,600
TO DEVELOP PROGRAMS ALONG THOSE

2229
01:20:09,600 --> 01:20:11,480
LINES BUT THERE CERTAINLY IS

2230
01:20:11,480 --> 01:20:12,120
RECOGNITION THAT'S CRITICALLY

2231
01:20:12,120 --> 01:20:13,080
IMPORTANT AND YOU MAY BE AWARE

2232
01:20:13,080 --> 01:20:16,040
THAT ALL OF THE INSTITUTES AND

2233
01:20:16,040 --> 01:20:18,360
CENTERS WORK WITH SPECIALISTS

2234
01:20:18,360 --> 01:20:21,160
WITHIN OUR INSTITUTES THAT HELP

2235
01:20:21,160 --> 01:20:22,600
US UNDERSTAND HOW BEST TO

2236
01:20:22,600 --> 01:20:25,160
COMMUNICATE TO POLICY MAKERS,

2237
01:20:25,160 --> 01:20:26,760
HOW TO UNDERSTAND WHAT WILL

2238
01:20:26,760 --> 01:20:28,120
RESONATE WITH THEM, YOU KNOW AND

2239
01:20:28,120 --> 01:20:30,240
HOW TO BE VERY CAREFUL POINTED

2240
01:20:30,240 --> 01:20:31,560
AND EFFECTIVE WITH OUR

2241
01:20:31,560 --> 01:20:32,000
COMMUNICATION.

2242
01:20:32,000 --> 01:20:34,800
SO THAT'S BEEN 1 OF THE THINGS I

2243
01:20:34,800 --> 01:20:36,160
FOUND MOST INTERESTING IN MY

2244
01:20:36,160 --> 01:20:39,120
ROLE, BUT OF COURSE, THAT

2245
01:20:39,120 --> 01:20:40,560
IS--THAT IS SUPPORT ASK

2246
01:20:40,560 --> 01:20:42,960
EXPERTISE THAT NOT ALL

2247
01:20:42,960 --> 01:20:43,960
RESEARCHERS AND SCIENTISTS HAVE

2248
01:20:43,960 --> 01:20:48,720
ACCESS TO, BUT YOU KNOW PERHAPS

2249
01:20:48,720 --> 01:20:53,440
DR. CLAYTON OR I SEE DR. WOYCHIK

2250
01:20:53,440 --> 01:20:54,760
CAN ADD TO COMMENTS ON THAT

2251
01:20:54,760 --> 01:20:55,560
IMPORTANT TOPIC.

2252
01:20:55,560 --> 01:20:57,960
>>THANKS SO MUCH FOR THAT
GREAT

2253
01:20:57,960 --> 01:20:59,040
QUESTION DR. JONES.

2254
01:20:59,040 --> 01:21:02,600
CLEARLY AN IMPORTANT PART OF

2255
01:21:02,600 --> 01:21:05,200
WHAT WE DO ALL AS SCIENTISTS AS

2256
01:21:05,200 --> 01:21:07,400
PART OF THE RESEARCH ECOSYSTEM

2257
01:21:07,400 --> 01:21:09,480
IS IT BEING ABLE TO PLAIN WHAT

2258
01:21:09,480 --> 01:21:11,840
WE'RE DOING AND WHY WE DO IT TO

2259
01:21:11,840 --> 01:21:15,200
A BROAD AUDIENCE AND AS

2260
01:21:15,200 --> 01:21:18,800
DR. CRISWELL MENTIONED WE

2261
01:21:18,800 --> 01:21:21,200
INTERNALLY WORK WITH SPECIALISTS

2262
01:21:21,200 --> 01:21:23,760
THAT DO THAT AND I PERSONALLY

2263
01:21:23,760 --> 01:21:25,640
PAY CLOSE ATTENTION TO THE

2264
01:21:25,640 --> 01:21:27,160
COMMUNICATION THAT ORWL PUTS OUT

2265
01:21:27,160 --> 01:21:29,560
TO INSURE THAT IT'S IN AS PLAIN

2266
01:21:29,560 --> 01:21:31,080
LANGUAGE AS POSSIBLE BUT YOU

2267
01:21:31,080 --> 01:21:32,160
ASKED ABOUT SCIENTISTS AND THEIR

2268
01:21:32,160 --> 01:21:35,560
EDUCATION AND SO I THINK THIS IS

2269
01:21:35,560 --> 01:21:38,960
A GREAT EXAMPLE OF AN

2270
01:21:38,960 --> 01:21:40,040
OPPORTUNITY FOR MORE

2271
01:21:40,040 --> 01:21:44,160
COLLABORATION BETWEEN NIH AND

2272
01:21:44,160 --> 01:21:45,600
ACADEMIC INSTITUTIONS TO INSURE

2273
01:21:45,600 --> 01:21:46,680
THAT THOSE SCIENTISTS OF THE

2274
01:21:46,680 --> 01:21:49,080
FUTURE ARE GETTING THE EDUCATION

2275
01:21:49,080 --> 01:21:50,720
THEY NEED, TRAINING, MENTORING

2276
01:21:50,720 --> 01:21:55,520
CAREER DEVELOPMENT AS

2277
01:21:55,520 --> 01:21:56,920
DR. RCRISWELL MENTIONED AT THE

2278
01:21:56,920 --> 01:21:58,120
HIGHEST LEVEL AND SHARE SCIENCE

2279
01:21:58,120 --> 01:22:00,200
WITH ANY AUDIENCE TO PLAIN WHY

2280
01:22:00,200 --> 01:22:01,880
SCIENCE IS IMPORTANT BECAUSE THE

2281
01:22:01,880 --> 01:22:04,080
FUTURE OF SOCIETY, YOU KNOW,

2282
01:22:04,080 --> 01:22:08,000
FROM OUR PERSPECTIVE, DEPENDS ON

2283
01:22:08,000 --> 01:22:09,800
SCIENTIFIC SOLUTIONS AS PART OF

2284
01:22:09,800 --> 01:22:11,040
THE EQUATION, NOT THE WHOLE

2285
01:22:11,040 --> 01:22:12,240
EQUAWGZ BUT PART OF THE

2286
01:22:12,240 --> 01:22:15,760
EQUATION, AND SO, I THINK

2287
01:22:15,760 --> 01:22:17,360
THROUGH K12 AND OTHER EFFORTS

2288
01:22:17,360 --> 01:22:18,520
THEY MAY BE OPPORTUNITIES TO

2289
01:22:18,520 --> 01:22:19,240
IMPROVE THAT.

2290
01:22:19,240 --> 01:22:22,320
I DO KNOW THAT RESEARCH AMERICA

2291
01:22:22,320 --> 01:22:25,640
HAS A SPECIFIC FELLOWSHIP ON

2292
01:22:25,640 --> 01:22:26,400
SCIENCE COMMUNICATION AND SO

2293
01:22:26,400 --> 01:22:27,600
THAT MIGHT BE SOMETHING THAT YOU

2294
01:22:27,600 --> 01:22:29,480
MIGHT WANT TO LOOK INTO.

2295
01:22:29,480 --> 01:22:30,880
I AM NOT AWARE OF OTHER

2296
01:22:30,880 --> 01:22:33,160
SOCIETIES OR ASSOCIATIONS THAT

2297
01:22:33,160 --> 01:22:35,080
DO, THEY MAY, I'M JUST NOT AWARE

2298
01:22:35,080 --> 01:22:36,960
OF THEM BUT THAT ALSO SHOWS THAT

2299
01:22:36,960 --> 01:22:38,600
THE ECOSYSTEM, THE RESEARCH

2300
01:22:38,600 --> 01:22:40,960
ECOSYSTEM INCLUDES SO MANY

2301
01:22:40,960 --> 01:22:41,760
DIFFERENT STAKEHOLDERS.

2302
01:22:41,760 --> 01:22:42,640
AND SCIENCE COMMUNICATION IS

2303
01:22:42,640 --> 01:22:45,280
SOMETHING THAT IS IMPORTANT TO

2304
01:22:45,280 --> 01:22:46,920
ALL OF US AND SO IN ORDER FOR US

2305
01:22:46,920 --> 01:22:50,160
TO BE ABLE TO HAVE THE MOST

2306
01:22:50,160 --> 01:22:52,520
ROBUST RETURNOT INVESTMENTS,

2307
01:22:52,520 --> 01:22:54,080
WE'RE ALL MAKING THESE ARE

2308
01:22:54,080 --> 01:22:55,280
PUBLICLY FUNDED RESEARCH AND ALL

2309
01:22:55,280 --> 01:22:57,640
INVESTMENTS WE WANT TO MAKE SURE

2310
01:22:57,640 --> 01:22:58,480
THAT INFORMATION'S REPORTED.

2311
01:22:58,480 --> 01:23:00,120
I SHOWED A SLIDE ON THE PROJECT

2312
01:23:00,120 --> 01:23:03,720
OUTCOMES SECTION OF THE FINAL

2313
01:23:03,720 --> 01:23:04,840
PROGRESS REPORT, THAT IS PART OF

2314
01:23:04,840 --> 01:23:06,040
THAT SECTION, THE PROJECT

2315
01:23:06,040 --> 01:23:08,560
OUTCOMES HAS TO BE WRITTEN IN

2316
01:23:08,560 --> 01:23:09,720
PLAIN LANGUAGE AND IS AVAILABLE

2317
01:23:09,720 --> 01:23:10,360
TO THE PUBLIC.

2318
01:23:10,360 --> 01:23:13,640
AND THAT'S WHY IT'S SO IMPORTANT

2319
01:23:13,640 --> 01:23:15,040
FOR THEM TO UNDERSTAND OUR

2320
01:23:15,040 --> 01:23:16,200
INVESTIGATORS THAT THEY NEED TO

2321
01:23:16,200 --> 01:23:19,000
BE ABLE TO CONVEY FOR EXAMPLE,

2322
01:23:19,000 --> 01:23:21,880
WHAT THE DIFFERENCES WERE, VALID

2323
01:23:21,880 --> 01:23:23,440
ANALYSIS, NOT NECESSARILY

2324
01:23:23,440 --> 01:23:25,280
STATISTICAL, VALID ANALYSIS FOR

2325
01:23:25,280 --> 01:23:27,520
SEX OR GENDER, RACE OR ETHNICITY

2326
01:23:27,520 --> 01:23:28,600
FOR PHASE 3 CLINICAL TRIALS,

2327
01:23:28,600 --> 01:23:30,920
WHICH ARE THOSE TRIALS THAT

2328
01:23:30,920 --> 01:23:34,080
REALLY INFORM TREATMENT

2329
01:23:34,080 --> 01:23:34,360
DECISIONS.

2330
01:23:34,360 --> 01:23:40,160
SO THANK YOU SO MUCH FOR THAT

2331
01:23:40,160 --> 01:23:40,400
QUESTION.

2332
01:23:40,400 --> 01:23:41,800
WITH THAT--

2333
01:23:41,800 --> 01:23:43,600
>>DR. JANINE, IF I CAN
MAKE A

2334
01:23:43,600 --> 01:23:44,200
COMMENT HERE.

2335
01:23:44,200 --> 01:23:44,480
>>YES.

2336
01:23:44,480 --> 01:23:46,440
>>IT HAS TO BE A PRIORITY
FOR

2337
01:23:46,440 --> 01:23:50,920
SCIENTISTS TO LEARN HOW TO SPEAK

2338
01:23:50,920 --> 01:23:54,400
TO NONSCIENTIFIC AUDIENCES.

2339
01:23:54,400 --> 01:23:55,600
AND WHILE WE'VE NEVER BEEN

2340
01:23:55,600 --> 01:23:57,480
TRAINED TO DO THIS AND A

2341
01:23:57,480 --> 01:23:58,440
PRESENTATION TO CONGRESSIONAL

2342
01:23:58,440 --> 01:24:00,640
BREFFING OR A PRESENTATION TO A

2343
01:24:00,640 --> 01:24:04,440
LAY AUDIENCE, IS JUST VERY

2344
01:24:04,440 --> 01:24:06,280
DIFFERENT THAN A PRESENTATION TO

2345
01:24:06,280 --> 01:24:06,920
A SCIENTIFIC AUDIENCE.

2346
01:24:06,920 --> 01:24:08,920
SO LEARNING HOW TO DO THAT AND

2347
01:24:08,920 --> 01:24:11,920
LEARNING HOW TO CONVEY COMPLEX

2348
01:24:11,920 --> 01:24:13,320
SCIENTIFIC MESSAGES BUT IN THE

2349
01:24:13,320 --> 01:24:17,040
CONTEXT OF KEEPING ALL THE

2350
01:24:17,040 --> 01:24:18,760
SCIENCE, THE SUBSTANCE OF THE

2351
01:24:18,760 --> 01:24:21,040
SCIENCE WITHOUT THE JARGON IS A

2352
01:24:21,040 --> 01:24:21,520
REAL CHALLENGE.

2353
01:24:21,520 --> 01:24:24,400
SO LEARNING HO YOU TO DO THIS

2354
01:24:24,400 --> 01:24:30,200
IS, IT JUST HAS TO BE A

2355
01:24:30,200 --> 01:24:30,560
PRIORITY.

2356
01:24:30,560 --> 01:24:31,720
>>DR. TEMPLE TON WOULD
YOU LIKE

2357
01:24:31,720 --> 01:24:33,360
TO MAKE ANOTHER COMMENT BEFORE

2358
01:24:33,360 --> 01:24:34,080
WE MOVE ON?

2359
01:24:34,080 --> 01:24:35,600
>>JUST REFLECTING ON WHAT
I PUT

2360
01:24:35,600 --> 01:24:37,280
IN THE CHAT, I COMPLETELY AGREE

2361
01:24:37,280 --> 01:24:39,200
WITH THIS, SO I INITIALLY WORKED

2362
01:24:39,200 --> 01:24:41,840
WITH THE AMERICAN ACADEMY OF

2363
01:24:41,840 --> 01:24:43,000
ORTHOPEDIC SURGEONS TO DEVELOP

2364
01:24:43,000 --> 01:24:45,240
THE WASHINGTON HAD HEGHT POLICY

2365
01:24:45,240 --> 01:24:47,160
FELLOWSHIP AND THAT'S WHERE

2366
01:24:47,160 --> 01:24:49,360
RESIDENTS WOULD SPEND 6 WEEKS

2367
01:24:49,360 --> 01:24:50,440
DURING AN ACADEMIC YEAR WORKING

2368
01:24:50,440 --> 01:24:52,200
ON POLICY AND HOW TO COMMUNICATE

2369
01:24:52,200 --> 01:24:52,800
WITH POLICY MAKERS CROSS

2370
01:24:52,800 --> 01:24:54,200
LINKINGY PART OF THE TIME IS

2371
01:24:54,200 --> 01:24:55,640
SPENT IN YOUR WASHINGTON D. C.

2372
01:24:55,640 --> 01:24:57,280
OFFICE AND THEY SPEND A LOT OF

2373
01:24:57,280 --> 01:24:59,360
TIME ON CAPITAL HILL, I

2374
01:24:59,360 --> 01:25:00,200
DEVELOPED THEN SOMETHING SIMILAR

2375
01:25:00,200 --> 01:25:02,120
FOR A MEDICAL SCHOOL WHERE

2376
01:25:02,120 --> 01:25:04,000
MEDICAL STUDENTS WOULD SPEND 1

2377
01:25:04,000 --> 01:25:06,480
OF THEIR ELECT LIVE ROTATIONS IN

2378
01:25:06,480 --> 01:25:07,480
TOPEKA KANSAS WORKING WITH THE

2379
01:25:07,480 --> 01:25:09,320
STATE MEDICAL SOCIETY AND

2380
01:25:09,320 --> 01:25:11,080
WORKING WITH THE CAPITAL, AGAIN

2381
01:25:11,080 --> 01:25:13,560
LEARNING HOW TO COMMUNICATE WITH

2382
01:25:13,560 --> 01:25:15,400
POLICY MAKERS, SO BOG THE

2383
01:25:15,400 --> 01:25:16,520
ELECTIVE IS STILL EXISTENT

2384
01:25:16,520 --> 01:25:17,440
ALTHOUGH IT'S HARD TO GET

2385
01:25:17,440 --> 01:25:18,360
STUDENTS TO DO IT BECAUSE THEY

2386
01:25:18,360 --> 01:25:23,280
DON'T WANT TO BE AWAY FROM HOME.

2387
01:25:23,280 --> 01:25:24,720
THE AOS POLICY WAS AROUND FOR

2388
01:25:24,720 --> 01:25:27,160
MANY YEARS AFTER I WAS NO LONGER

2389
01:25:27,160 --> 01:25:28,800
LEADING THIS BUT UNFORTUNATELY

2390
01:25:28,800 --> 01:25:31,000
IT WENT AWAY BECAUSE OF LACK OF

2391
01:25:31,000 --> 01:25:31,280
FUNDING.

2392
01:25:31,280 --> 01:25:32,160
BUT PERHAPS SOMETHING SIMILAR TO

2393
01:25:32,160 --> 01:25:33,120
THIS WHERE YOU HAVE THOSE ININ

2394
01:25:33,120 --> 01:25:35,680
TRANSLATIONAL RESEARCHING SO YOU

2395
01:25:35,680 --> 01:25:37,320
CATCH THEM EARLY BUT STILL LATE

2396
01:25:37,320 --> 01:25:38,480
ENOUGH IN THE PROCESS THEY KNOW

2397
01:25:38,480 --> 01:25:40,600
WHAT THEY'RE TALKING ABOUT.

2398
01:25:40,600 --> 01:25:42,480
BUT WITH SUPERVISION FROM BOTH

2399
01:25:42,480 --> 01:25:43,480
THE HEALTHCARE PROFESSIONAL AND

2400
01:25:43,480 --> 01:25:44,520
SCIENCE SIDE BUT THEN SUPER

2401
01:25:44,520 --> 01:25:46,280
VISION FROM THE HEALTH POLICY

2402
01:25:46,280 --> 01:25:47,320
SIDE TO HELP THEM UNDERSTAND

2403
01:25:47,320 --> 01:25:49,240
THIS BETTER AND HAVE THIS BE

2404
01:25:49,240 --> 01:25:51,960
PART OF WHAT IT IS THAT THEY DO

2405
01:25:51,960 --> 01:25:55,440
AND PART OF THEIR LEXICON.

2406
01:25:55,440 --> 01:25:56,480
>>JUST ANOTHER QUICK
COMMENT IS

2407
01:25:56,480 --> 01:25:59,160
THAT IF YOU'RE INTERESTED IN

2408
01:25:59,160 --> 01:26:01,640
SCIENCE COMMUNICATION, ALAN

2409
01:26:01,640 --> 01:26:03,760
ALDA, HAS TAKEN ON AS SCIENCE

2410
01:26:03,760 --> 01:26:05,480
COMMUNICATION IN A REALLY BIG

2411
01:26:05,480 --> 01:26:07,920
WAY, HE'S DOING THIS THROUGH

2412
01:26:07,920 --> 01:26:09,760
STONY BROOK UNIVERSITY, SO DO A

2413
01:26:09,760 --> 01:26:11,560
GOOGLE SEARCH ON ALAN ALDA, AND

2414
01:26:11,560 --> 01:26:15,320
IF YOU EVER LISTEN TO SCIENCE

2415
01:26:15,320 --> 01:26:16,440
FRIDAY, HIS PODCAST AS I DO, HE

2416
01:26:16,440 --> 01:26:18,640
WAS ON IT AND TALKED ABOUT THE

2417
01:26:18,640 --> 01:26:20,440
REALLY IMPORTANT THINGS THAT

2418
01:26:20,440 --> 01:26:21,120
NEED TO--REALLY IMPORTANT

2419
01:26:21,120 --> 01:26:22,400
STRATEGIES THAT SCIENTISTS NEED

2420
01:26:22,400 --> 01:26:27,160
TO TAKE TO COMMUNICATE THEIR

2421
01:26:27,160 --> 01:26:27,840
RESEARCH RESULTS.

2422
01:26:27,840 --> 01:26:29,000
>>THANKS FOR MENTIONING
THAT

2423
01:26:29,000 --> 01:26:34,200
RICK, AND I FORGOT TO MENTION

2424
01:26:34,200 --> 01:26:36,400
TRIP AAAS, AND SO GREAT QUESTION

2425
01:26:36,400 --> 01:26:37,560
DR. JONES, SEE YOU ALREADY ARE

2426
01:26:37,560 --> 01:26:40,160
SHOWING US THAT WE MIDA GREAT

2427
01:26:40,160 --> 01:26:44,440
CHOICE WITH INCLUDING YOU AS A

2428
01:26:44,440 --> 01:26:46,400
NEW MEMBER OF THE GROUP, SO WE

2429
01:26:46,400 --> 01:26:47,800
ARE THINKING OF THING WE NEED TO

2430
01:26:47,800 --> 01:26:48,160
THINK OF.

2431
01:26:48,160 --> 01:26:51,560
AND WITH THAT I WANT TO THANK

2432
01:26:51,560 --> 01:26:53,680
DR. CRISWELL, PER JOINING US AND

2433
01:26:53,680 --> 01:26:54,640
PARTNERING WITH US AND LOOK

2434
01:26:54,640 --> 01:26:55,920
FORWARD TO BRINGING HER BACK TO

2435
01:26:55,920 --> 01:26:57,800
SHOW YOU THE GREAT RESULTS WE

2436
01:26:57,800 --> 01:26:59,600
GET IN SOME TIME.

2437
01:26:59,600 --> 01:27:02,320
SO THANK YOU LINDE FOR JOINING

2438
01:27:02,320 --> 01:27:04,200
US--LINDE FOR JOINING US TODAY,

2439
01:27:04,200 --> 01:27:04,760
WE APPRECIATE THAT.

2440
01:27:04,760 --> 01:27:07,200
>>MY PLEASURE, THANK YOU
SO

2441
01:27:07,200 --> 01:27:07,480
MUCH.

2442
01:27:07,480 --> 01:27:07,840
>>ABSOLUTELY.

2443
01:27:07,840 --> 01:27:09,360
AND NOW WE HAVE THE PRIVILEGE OF

2444
01:27:09,360 --> 01:27:11,760
MOVING FORWARD WITH DR. RICK

2445
01:27:11,760 --> 01:27:15,240
WOYCHIK, I WOULD LIKE TO

2446
01:27:15,240 --> 01:27:17,160
INTRODUCE THE NEWEST DIRECTOR OF

2447
01:27:17,160 --> 01:27:19,120
NIEHS, WE WAS NAMED DIRECTOR IN

2448
01:27:19,120 --> 01:27:21,240
TWEBT 20 AND HE'S ALSO DIRECTOR

2449
01:27:21,240 --> 01:27:23,640
OF THE NATIONAL TOXICOLOGY

2450
01:27:23,640 --> 01:27:27,000
PROGRAM WITH RELATES TO DHHS

2451
01:27:27,000 --> 01:27:30,120
REPORTS, RELATES TO DHHS AT

2452
01:27:30,120 --> 01:27:31,640
TOXICOLOGY RESEARCH, AMONG

2453
01:27:31,640 --> 01:27:34,840
NIEHS, THE NATIONAL CENTER FOR

2454
01:27:34,840 --> 01:27:38,040
TOXICOLOGICAL RESEARCH AT FDA,

2455
01:27:38,040 --> 01:27:39,240
AND SOME CDC AREAS AS WELL.

2456
01:27:39,240 --> 01:27:41,880
SO HE'S GOT A BIG, BIG JOB

2457
01:27:41,880 --> 01:27:44,680
THERE, HE CAME TO NIH IN 2010

2458
01:27:44,680 --> 01:27:47,240
WHEN HE WAS NAMED DEPUTY

2459
01:27:47,240 --> 01:27:49,040
DIRECTOR OF NIEHS, BUT BEFORE

2460
01:27:49,040 --> 01:27:51,080
THAT, HE IS A MOLECULAR

2461
01:27:51,080 --> 01:27:53,680
GENETICIST WITH A Ph.D. IN

2462
01:27:53,680 --> 01:27:55,280
MOLECULAR BIOLOGY FROM CASE

2463
01:27:55,280 --> 01:27:56,320
WESTERN RESERVE UNIVERSITY AND

2464
01:27:56,320 --> 01:27:58,640
NEEDED HIS POST DOC WITH THE

2465
01:27:58,640 --> 01:28:00,280
LEADER AT HARVARD MEDICAL

2466
01:28:00,280 --> 01:28:00,520
SCHOOL.

2467
01:28:00,520 --> 01:28:03,200
HE SPENT 10 YEARS AT THE

2468
01:28:03,200 --> 01:28:04,320
ECOSYSTEMS RIDGE NATIONAL

2469
01:28:04,320 --> 01:28:06,200
LABORATORY AND WAS VICE CHAIR AT

2470
01:28:06,200 --> 01:28:07,520
PEDIATRICS IN CASE WESTERN AND

2471
01:28:07,520 --> 01:28:08,760
WORKED IN PHARMA FOR MANY YEARS

2472
01:28:08,760 --> 01:28:11,120
AS WELL AND THEN WAS A CEO OF

2473
01:28:11,120 --> 01:28:13,800
THE JACKSON LABS BEFORE HE CAME

2474
01:28:13,800 --> 01:28:14,600
TO NIEHS.

2475
01:28:14,600 --> 01:28:18,800
SO HE'S DISCOVERED MANY THINGS

2476
01:28:18,800 --> 01:28:20,080
I'LL JUST MENTION THE CANNED

2477
01:28:20,080 --> 01:28:22,200
WHAT AS 1 OF HIS LANDMARK

2478
01:28:22,200 --> 01:28:24,480
CONTRIBUTIONS IN THE FIELD OF

2479
01:28:24,480 --> 01:28:27,600
ENVIRONMENT WILL EPIGENETICS AND

2480
01:28:27,600 --> 01:28:32,800
MAMMALIAN GENETICS SO WITH THAT

2481
01:28:32,800 --> 01:28:33,960
DR. WOYCHIK, WE'RE DELIGHTED TO

2482
01:28:33,960 --> 01:28:36,480
HAVE YOU HERE TODAY.

2483
01:28:36,480 --> 01:28:37,600
SNR TEROFFIC.

2484
01:28:37,600 --> 01:28:39,080
OKAY, LET ME SEE MY SLIDES ARE

2485
01:28:39,080 --> 01:28:40,520
UP, THANK YOU FOR SHARING YOUR

2486
01:28:40,520 --> 01:28:40,880
SCREEN.

2487
01:28:40,880 --> 01:28:42,280
CAN EVERYONE HEAR ME OKAY, I

2488
01:28:42,280 --> 01:28:43,800
DON'T WANT TO START MY LECTURE

2489
01:28:43,800 --> 01:28:44,880
AND NO 1 CAN HEAR ME.

2490
01:28:44,880 --> 01:28:46,320
>>WE CAN HEAR YOU.

2491
01:28:46,320 --> 01:28:46,680
>>TERRIFIC.

2492
01:28:46,680 --> 01:28:49,840
LET ME JUST SAY FIRST OF ALL

2493
01:28:49,840 --> 01:28:51,040
THAT IT'S JUST WONDERFUL TO BE

2494
01:28:51,040 --> 01:28:52,600
HERE WITH YOU THIS MORNING AND

2495
01:28:52,600 --> 01:28:55,440
THANKS DR. CLAYTON FOR THIS

2496
01:28:55,440 --> 01:28:57,200
OPPORTUNITY TO PRESENT THE WORK

2497
01:28:57,200 --> 01:29:00,000
AND I WILL FOCUS ON TALKING

2498
01:29:00,000 --> 01:29:02,080
ABOUT SOME OF THE ISSUES

2499
01:29:02,080 --> 01:29:04,800
RELATING TO HOW CLIMATE CHANGE

2500
01:29:04,800 --> 01:29:07,680
AFFECTS WOMEN'S HEALTH WHICH IS

2501
01:29:07,680 --> 01:29:10,680
WHAT I INTEND TO DO AND IN THE

2502
01:29:10,680 --> 01:29:13,000
EXCHANGE YOU HAD WITH

2503
01:29:13,000 --> 01:29:15,000
DR. CRISWELL, IT'S A HIGHLY

2504
01:29:15,000 --> 01:29:16,520
COLLABORATIVE PROGRAM, THE

2505
01:29:16,520 --> 01:29:18,040
COLLABORATED ACROSS ALL OF NIH

2506
01:29:18,040 --> 01:29:20,000
AND OTHER HHS AGENCIES IT HAS TO

2507
01:29:20,000 --> 01:29:21,680
BE BECAUSE IT'S A BIG PROBLEM.

2508
01:29:21,680 --> 01:29:23,800
BUT I THOUGHT I WOULD ALSO TACK

2509
01:29:23,800 --> 01:29:25,280
A FEW MINUTES AND TALK ABOUT THE

2510
01:29:25,280 --> 01:29:29,080
WORK WE DO AT NIEHS, SO I HOPE

2511
01:29:29,080 --> 01:29:31,040
YOU DON'T MIND IF I DO THAT JUST

2512
01:29:31,040 --> 01:29:34,120
TO MAKE SURE THAT YOU AND STAFF

2513
01:29:34,120 --> 01:29:36,360
AT THE OFFICE OF RESEARCH AND

2514
01:29:36,360 --> 01:29:37,760
WOMEN'S HEALTH ARE FULLY AWARE

2515
01:29:37,760 --> 01:29:39,080
OF THE BROAD SPECTRUM OF

2516
01:29:39,080 --> 01:29:41,600
DIFFERENT THINGS WE DO AT NIEHS,

2517
01:29:41,600 --> 01:29:44,320
SO LET'S GO TO THE NEXT SLIDE,

2518
01:29:44,320 --> 01:29:44,720
PLEASE.

2519
01:29:44,720 --> 01:29:46,720
SO IN THIS DISCUSSION ABOUT

2520
01:29:46,720 --> 01:29:49,760
NIEHS, I WILL JUST SAY RIGHT UP

2521
01:29:49,760 --> 01:29:52,040
FRONT WHAT DIFFERENTIATES US

2522
01:29:52,040 --> 01:29:54,960
FROM THE 26 OTHERS ICs, AND

2523
01:29:54,960 --> 01:29:56,960
CENTERS AND OFFICES, ACROSS THE

2524
01:29:56,960 --> 01:29:58,600
NIH, OUR MISSION AND OUR VISION.

2525
01:29:58,600 --> 01:30:00,640
SO OUR MISSION IS TO DISCOVER

2526
01:30:00,640 --> 01:30:01,720
HOW THE ENVIRONMENT AFFECTS

2527
01:30:01,720 --> 01:30:04,120
PEOPLE IN ORDER TO PROMOTE

2528
01:30:04,120 --> 01:30:05,520
HEALTHIER LIVES, AND OUR VISION

2529
01:30:05,520 --> 01:30:08,520
IS TO PROVIDE GLOBAL LEADERSHIP

2530
01:30:08,520 --> 01:30:09,680
FOR INNOVATIVE RESEARCH FOR

2531
01:30:09,680 --> 01:30:11,080
PUBLIC HEALTH BY VERMEN INFECTED

2532
01:30:11,080 --> 01:30:13,760
VENTING DISEASE AND DISABILITY.

2533
01:30:13,760 --> 01:30:15,560
SO THE 2 ELEMENTS OF THE VISION

2534
01:30:15,560 --> 01:30:17,560
I WANT TO EMPHASIZE ARE THE

2535
01:30:17,560 --> 01:30:22,360
INNOVATION AND THE PREVENTION.

2536
01:30:22,360 --> 01:30:28,840
SO IN, IEHS AIMS TO PROVIDE AS

2537
01:30:28,840 --> 01:30:30,240
THE DEFINITIVE GLOBAL AND HEALTH

2538
01:30:30,240 --> 01:30:31,000
SCIENCENESS COMMUNITY AND WE

2539
01:30:31,000 --> 01:30:32,600
WANT TO PROMOTE THE TYPE OF

2540
01:30:32,600 --> 01:30:33,960
INNOVATIVE THINKING THAT WILL

2541
01:30:33,960 --> 01:30:35,040
KIEP THE ENVIRONMENTAL HEALTH

2542
01:30:35,040 --> 01:30:35,760
SCIENCES COMMUNITY AT THE

2543
01:30:35,760 --> 01:30:38,280
CUTTING EDGE OF ADVANCING HUMAN

2544
01:30:38,280 --> 01:30:38,840
HEALTH.

2545
01:30:38,840 --> 01:30:40,040
SO ADDITIONALLY AND PROBABLY

2546
01:30:40,040 --> 01:30:41,000
MOST IMPORTANT THE PRIMARY

2547
01:30:41,000 --> 01:30:43,800
PHOBEUS OF THE WORK AT NIEHS IS

2548
01:30:43,800 --> 01:30:46,600
ON THE PREVENTION OF ADVERSE

2549
01:30:46,600 --> 01:30:46,960
HEALTH EFFECTS.

2550
01:30:46,960 --> 01:30:49,160
SOPHISTICATEDY WE AIM TO DO THIS

2551
01:30:49,160 --> 01:30:50,240
CAREFULLY BY STUDYING THE

2552
01:30:50,240 --> 01:30:51,680
ENVIRONMENT AND FACTORS WITH THE

2553
01:30:51,680 --> 01:30:56,480
ENVIRONMENT THAT CAN NEGATIVELY,

2554
01:30:56,480 --> 01:30:57,800
YOU SHOULD THE TOXICOLOGY

2555
01:30:57,800 --> 01:30:59,600
FRAMEWORK BUT ALSO POSITIVELY

2556
01:30:59,600 --> 01:31:00,880
IMPACT HUMAN HEALTH SO IT'S

2557
01:31:00,880 --> 01:31:02,080
ABOUT BOTH OF THESE DIFFERENT

2558
01:31:02,080 --> 01:31:04,640
THINGS. 

2559
01:31:04,640 --> 01:31:06,920
SO NEXT SLIDE; SO WHOOPS LET'S

2560
01:31:06,920 --> 01:31:07,400
GO BACK.

2561
01:31:07,400 --> 01:31:08,600
THERE WE ARE SO TO HELP YOU

2562
01:31:08,600 --> 01:31:10,680
UNDERSTAND WHAT WE DO AT NIEHS,

2563
01:31:10,680 --> 01:31:15,560
AGAIN I WILL BE RELATIVELY BRIEF

2564
01:31:15,560 --> 01:31:18,240
ON THIS I WANT TOUC ABOUT OUR

2565
01:31:18,240 --> 01:31:20,720
STRATEGIC PLAN, THERE ARE 3

2566
01:31:20,720 --> 01:31:21,640
THEMES OF OUR STRATEGIC PLAN AND

2567
01:31:21,640 --> 01:31:23,520
THE FIRST PLAN IS ABOUT

2568
01:31:23,520 --> 01:31:24,800
ADVANCING HEALTH SCIENCES AND IT

2569
01:31:24,800 --> 01:31:27,280
IS A BIG THEME AND INVOLVES

2570
01:31:27,280 --> 01:31:28,800
STUDYING HOW ENVIRONMENTAL

2571
01:31:28,800 --> 01:31:30,920
EXPOSURES IMPACT ALL LEVELS

2572
01:31:30,920 --> 01:31:32,920
BIOLOGICAL ORGANIZATION FROM THE

2573
01:31:32,920 --> 01:31:33,600
MOLECULAR AND BIOCHEMICAL

2574
01:31:33,600 --> 01:31:35,200
PATHWAY TO THE CELLULAR TISSUE

2575
01:31:35,200 --> 01:31:37,160
ORGAN, YOU KNOW SYSTEM SYSTEM

2576
01:31:37,160 --> 01:31:38,320
BASED MODEL ORGANISMS AT THE

2577
01:31:38,320 --> 01:31:40,720
INDIVIDUAL AND THE POPULATION

2578
01:31:40,720 --> 01:31:40,960
LEVELS.

2579
01:31:40,960 --> 01:31:42,920
AND WE ARE DOING THIS AT ALL

2580
01:31:42,920 --> 01:31:45,240
STAGES ACROSS THE LIFE SPAN FROM

2581
01:31:45,240 --> 01:31:46,920
PRECONCEPTION THROUGH OLD AGE.

2582
01:31:46,920 --> 01:31:49,080
SO IT'S A BIG THEME AND WE DO A

2583
01:31:49,080 --> 01:31:50,920
LOT OF WORK AND I WILL TALK MORE

2584
01:31:50,920 --> 01:31:52,120
SPECIFICALLY ABOUT THE WORK WE

2585
01:31:52,120 --> 01:31:54,000
DO AS IT RELATES TO WOMEN'S

2586
01:31:54,000 --> 01:31:56,120
HEALTH IN JUST A COUPLE OF

2587
01:31:56,120 --> 01:31:56,360
MINUTES.

2588
01:31:56,360 --> 01:31:58,720
SO THE SECOND THEME IS ABOUT

2589
01:31:58,720 --> 01:31:59,760
PROMOTING AND TRANSLATION, SO

2590
01:31:59,760 --> 01:32:01,800
DATA TO KNOWLEDGE TO ACTION.

2591
01:32:01,800 --> 01:32:03,360
SO THIS THEME RECOGNIZES THAT

2592
01:32:03,360 --> 01:32:05,800
THE VALUE OF ADVANCING HEALTH

2593
01:32:05,800 --> 01:32:07,120
SCIENCES CAN ONLY BE FULLY

2594
01:32:07,120 --> 01:32:08,800
REALIZED THROUGH THE TRANALATION

2595
01:32:08,800 --> 01:32:10,640
OF OUR SCIENCE SO IT CAN BE USED

2596
01:32:10,640 --> 01:32:12,920
BY THE PUBLIC, BY HEALTH

2597
01:32:12,920 --> 01:32:14,080
PROVIDERS, REGULATORS AND POLICY

2598
01:32:14,080 --> 01:32:15,440
MAKERS AND I'M HOPING THIS WILL

2599
01:32:15,440 --> 01:32:17,160
HELP TO INFORM THE DECISIONS

2600
01:32:17,160 --> 01:32:17,880
THEY MAKE.

2601
01:32:17,880 --> 01:32:20,320
SO IN THE CONTEXT OF OUR

2602
01:32:20,320 --> 01:32:22,840
DISCUSSION ABOUT COMMUNICATING

2603
01:32:22,840 --> 01:32:24,480
SCIENCE RESULTS, THIS SQUARELY

2604
01:32:24,480 --> 01:32:26,320
FITS WITHIN THE SECOND AIM OF

2605
01:32:26,320 --> 01:32:27,360
OUR STRATEGIC PLAN.

2606
01:32:27,360 --> 01:32:28,400
HOW DO WE COMMUNICATE THOSE

2607
01:32:28,400 --> 01:32:30,120
RESULTS IN A WAY THAT WE CAN

2608
01:32:30,120 --> 01:32:33,520
ACTUALLY HAVE AN IMPACT ON THE

2609
01:32:33,520 --> 01:32:35,240
HEALTH OF INDIVIDUALS WITHIN OUR

2610
01:32:35,240 --> 01:32:35,520
COMMUNITY.

2611
01:32:35,520 --> 01:32:39,840
I WILL TALK A BIT ABOUT THE WORK

2612
01:32:39,840 --> 01:32:42,200
THAT YOU'RE COSPONSORING WHICH I

2613
01:32:42,200 --> 01:32:44,480
WILL SPEAK ON IN A FEW MINUES.

2614
01:32:44,480 --> 01:32:46,920
SO THE THIRD THEME IS ADVANCING

2615
01:32:46,920 --> 01:32:47,960
SCIENCE THROUGH STEWARDSHIP AND

2616
01:32:47,960 --> 01:32:48,200
SUPPORT.

2617
01:32:48,200 --> 01:32:50,240
WE RECOGNIZE THAT THE SUCCESS OF

2618
01:32:50,240 --> 01:32:51,560
OUR MISSION REQUIRES THAT WE

2619
01:32:51,560 --> 01:32:52,880
CONTINUE TO PROVIDE STRONG

2620
01:32:52,880 --> 01:32:54,240
LEADERSHIP OF OUR HUMAN OR

2621
01:32:54,240 --> 01:32:55,680
FINANCIAL AND INSTRAY JECTORY

2622
01:32:55,680 --> 01:32:56,600
STRUCTURE RESOURCES.

2623
01:32:56,600 --> 01:32:57,840
SO INCLUDED IN THIS THIRD THEME

2624
01:32:57,840 --> 01:33:00,320
OF OUR PLAN IS ENGAGING

2625
01:33:00,320 --> 01:33:01,960
INVESTIGATORS FROM OUTSIDE

2626
01:33:01,960 --> 01:33:02,720
ENVIRONMENTAL HEALTH SCIENCES SO

2627
01:33:02,720 --> 01:33:04,920
THEY CAN BRING THEIR KNOWLEDGE

2628
01:33:04,920 --> 01:33:07,360
AND CAPABILITIES INTO THE

2629
01:33:07,360 --> 01:33:08,280
ENVIRONMENTAL HEALTH SCIENCES TO

2630
01:33:08,280 --> 01:33:10,680
HELP US ACHIEVE OUR MISSION.

2631
01:33:10,680 --> 01:33:12,400
SO HOPEFULLY YOU WILL RECOGNIZE

2632
01:33:12,400 --> 01:33:14,000
THAT WE DO TOXICOLOGY RESEARCH

2633
01:33:14,000 --> 01:33:15,920
AND I AS YOU'VE INDICATED

2634
01:33:15,920 --> 01:33:18,000
DR. CLAYTON THE DIRECTOR OF THE

2635
01:33:18,000 --> 01:33:18,600
NATIONAL TOXICOLOGY PROGRAM BUT

2636
01:33:18,600 --> 01:33:23,640
WE DO A LOT MORE THAN JUST

2637
01:33:23,640 --> 01:33:24,840
TOXICOLOGY SCIENCE AND WE WILL

2638
01:33:24,840 --> 01:33:27,960
UPDATE, BOY THE WAY I WANTED TO

2639
01:33:27,960 --> 01:33:28,960
COMMENT RELATIVE STRATEGIC

2640
01:33:28,960 --> 01:33:30,560
PLANS, WE WILL UPDATE OUR PLAN

2641
01:33:30,560 --> 01:33:35,640
THIS NEXT YEAR, SO STAY TUNED

2642
01:33:35,640 --> 01:33:39,440
WE'LL BE ISSUING AN RFI SOON AND

2643
01:33:39,440 --> 01:33:40,960
WILL BE WELCOMING ANY AND ALL

2644
01:33:40,960 --> 01:33:42,240
INPUT AS WE ABOUT FORWARD.

2645
01:33:42,240 --> 01:33:42,720
SO NEXT SLIDE.

2646
01:33:42,720 --> 01:33:45,080
TO GIVE YOU A SENSE OF THE

2647
01:33:45,080 --> 01:33:48,400
ENORMITY OF OUR CHALLENGE AND

2648
01:33:48,400 --> 01:33:49,400
STUDYING THE ENVIRONMENTS, SO

2649
01:33:49,400 --> 01:33:51,440
AGAIN, IT GOES WELL BEYOND JUST

2650
01:33:51,440 --> 01:33:52,920
TOXICOLOGY SCIENCE, OF COURSE WE

2651
01:33:52,920 --> 01:33:56,320
DO SOME TOXICOLOGY WORK, WE

2652
01:33:56,320 --> 01:33:57,080
DEFINE THE ENVIRONMENTAL

2653
01:33:57,080 --> 01:33:58,240
RESEARCH BROADLY TO INCLUDE A

2654
01:33:58,240 --> 01:34:00,480
WHOLE VARIETY OF DIFFERENT

2655
01:34:00,480 --> 01:34:01,080
ENVIRONMENTAL EXPOSURES THAT

2656
01:34:01,080 --> 01:34:02,360
YOU'RE SEEING ON THIS SLIDE.

2657
01:34:02,360 --> 01:34:06,320
SO THEY'RE ALL EXPOSURES THAT

2658
01:34:06,320 --> 01:34:08,120
CAN ULTIMATELY INFLUENCE HUMAN

2659
01:34:08,120 --> 01:34:10,280
HEALTH, WE SO STUDY CHEMICALS IN

2660
01:34:10,280 --> 01:34:12,320
PRODUCTS AND BUILDING MATERIALS,

2661
01:34:12,320 --> 01:34:15,560
WE STUDY PRODUCTS IN AIR, SOIL

2662
01:34:15,560 --> 01:34:16,760
AND WATER, AGRICULTURAL

2663
01:34:16,760 --> 01:34:20,080
CHEMICALS, WE STUDY SYNTHETIC

2664
01:34:20,080 --> 01:34:21,600
CHEMICALS PIF, AS, AND IT'S BEEN

2665
01:34:21,600 --> 01:34:23,240
IN THE NEWS RECEIPTLY AND IN

2666
01:34:23,240 --> 01:34:25,880
MANY OF YOU PROBABLY KNOW THESE

2667
01:34:25,880 --> 01:34:27,160
AS TEFLON AND SCOTCH GUARD.

2668
01:34:27,160 --> 01:34:28,840
YOU HAVE TO BE CAREFUL WHEN

2669
01:34:28,840 --> 01:34:31,560
YOU'RE SPRAYING YOUR HIKING

2670
01:34:31,560 --> 01:34:32,480
BOOTS WITH SCOTCH GUARD, YOU

2671
01:34:32,480 --> 01:34:34,400
DON'T WANT TO BROAGHT THAT

2672
01:34:34,400 --> 01:34:34,760
STUFF.

2673
01:34:34,760 --> 01:34:38,320
SO WE EVALUATE AND WE

2674
01:34:38,320 --> 01:34:39,680
RECOGNIZE,Y WE EVALUATE IT IS

2675
01:34:39,680 --> 01:34:41,440
HEALTH WITH COSMETICS AND

2676
01:34:41,440 --> 01:34:43,320
SUNSCREENS AND THE INFLUENCE OF

2677
01:34:43,320 --> 01:34:46,360
LIFESTYLE FACTORS SUCH AS

2678
01:34:46,360 --> 01:34:46,920
NUTRITION, SMOKING, VAPING

2679
01:34:46,920 --> 01:34:47,880
PSYCHOSOCIAL STRESS AND

2680
01:34:47,880 --> 01:34:49,600
EXERCISE, SO FOR EXAMPLE, WE'RE

2681
01:34:49,600 --> 01:34:51,280
STUDYING HOW GREEN FACES IN

2682
01:34:51,280 --> 01:34:53,320
URBAN ENVIRONMENTS CAN POSITIVE

2683
01:34:53,320 --> 01:34:55,760
IMPACT U MAN HEALTH OR LACK OF

2684
01:34:55,760 --> 01:34:57,680
GREEN SPACES CAN NEGATIVELY

2685
01:34:57,680 --> 01:35:00,800
IMPACT HUMAN HEALTH AND GRANTEES

2686
01:35:00,800 --> 01:35:03,280
WHO ARE STUDYING THE COMSUMPTION

2687
01:35:03,280 --> 01:35:05,320
OF FRUITS WITH POLYPHENOLS AND

2688
01:35:05,320 --> 01:35:07,760
OTHERS WITH OMEGA 3 FATTY ACID,

2689
01:35:07,760 --> 01:35:10,480
SO HOW DOES DIET BE POSITIVELY

2690
01:35:10,480 --> 01:35:15,440
IMPACING OUR HEALTH AND

2691
01:35:15,440 --> 01:35:16,720
POTENTIALLY NEUTRALIZING THOSE

2692
01:35:16,720 --> 01:35:17,000
EXPOSURES.

2693
01:35:17,000 --> 01:35:19,320
SO STRONG FOCUS AT THE WORK AT

2694
01:35:19,320 --> 01:35:21,640
NIEHS IS TO STUDY THE IMPACT OF

2695
01:35:21,640 --> 01:35:22,600
HEALTH DISPARITIES AND

2696
01:35:22,600 --> 01:35:24,360
STRUCTURAL RACISM AND MODEL

2697
01:35:24,360 --> 01:35:26,400
CITIZEN 1 OF OUR MORE RECENT

2698
01:35:26,400 --> 01:35:28,840
COUNCIL MEETINGS WE'VE COME TO

2699
01:35:28,840 --> 01:35:31,080
DEFINE THAT STRUCTURAL RACISM IS

2700
01:35:31,080 --> 01:35:33,840
ANA VERSE ENVIRONMENTAL EXPOSURE

2701
01:35:33,840 --> 01:35:35,760
AND IT ABSOLUTELY NEGATIVELY

2702
01:35:35,760 --> 01:35:36,320
AFFECTS HUMAN HEALTH.

2703
01:35:36,320 --> 01:35:38,000
SO THE BOTTOM LINE IS WE'RE

2704
01:35:38,000 --> 01:35:39,800
INTERESTED IN HOW A BROAD

2705
01:35:39,800 --> 01:35:41,080
ASSORTMENT OF ENVIRONMENTAL

2706
01:35:41,080 --> 01:35:44,080
EXPOSURES CAN AGAIN POSITIVELY

2707
01:35:44,080 --> 01:35:45,680
OR NEGATIVELY IMPACT HUMAN

2708
01:35:45,680 --> 01:35:46,040
HEALTH.

2709
01:35:46,040 --> 01:35:47,440
WELL, CLICK, PLEASE, SO PART OF

2710
01:35:47,440 --> 01:35:49,760
THE REASON WHY PART THE DOCTOR

2711
01:35:49,760 --> 01:35:51,280
SOPHISTICATED CHOSE ME AS THE

2712
01:35:51,280 --> 01:35:52,840
DEPUTY DIRECTOR OF NIEHS,

2713
01:35:52,840 --> 01:35:54,720
SOMEONE COME NOTHING WITH

2714
01:35:54,720 --> 01:35:56,560
BACKGROUND IN MAMMALIAN AND

2715
01:35:56,560 --> 01:36:00,520
HUMAN GENETICS, SO OUR WORK ALSO

2716
01:36:00,520 --> 01:36:01,720
INCREASINGLY INVOLVES STUDYING

2717
01:36:01,720 --> 01:36:02,840
DIFFERENCES IN THE WAY THAT EACH

2718
01:36:02,840 --> 01:36:05,080
OF US RESPHOND A GIVEN

2719
01:36:05,080 --> 01:36:05,800
ENVIRONMENTAL EXPOSURE, SO

2720
01:36:05,800 --> 01:36:06,960
DIFFERENT INDIVIDUALS I THINK AS

2721
01:36:06,960 --> 01:36:09,400
WE KNOW WITH THEIR OWN GENETIC

2722
01:36:09,400 --> 01:36:10,360
AND BIOLOGICAL MAKE UP RESPOND

2723
01:36:10,360 --> 01:36:11,480
TO THE ENVIRONMENT IN DIFFERENT

2724
01:36:11,480 --> 01:36:12,240
WAYS.

2725
01:36:12,240 --> 01:36:14,320
SO WHAT MAY BE DANGEROUS OR WHAT

2726
01:36:14,320 --> 01:36:16,280
MAY MAKE SOMEONE SICK OF A GIVEN

2727
01:36:16,280 --> 01:36:18,400
DOSE MAY NOT HAVE THE SAME

2728
01:36:18,400 --> 01:36:19,440
EFFECT ON SOMEONE ELSE.

2729
01:36:19,440 --> 01:36:25,320
SO CLICK IT AGAIN PLEASE.

2730
01:36:25,320 --> 01:36:27,120
SO WHAT'S EMERGE SUGGEST A

2731
01:36:27,120 --> 01:36:29,440
PRETTY EXCITING NEW CONCEPT IT'S

2732
01:36:29,440 --> 01:36:30,280
CALLED PRECISION ENVIRONMENTAL

2733
01:36:30,280 --> 01:36:30,520
HEALTH.

2734
01:36:30,520 --> 01:36:37,040
SO THIS IS WHERE WE STUDY THE

2735
01:36:37,040 --> 01:36:37,800
GENE-BIOENVIRONMENT EFFECTS SO

2736
01:36:37,800 --> 01:36:39,640
WE STUDY THE GENETICS BUT WE

2737
01:36:39,640 --> 01:36:41,320
ALSO STUDY THE EPIGENETIC AND

2738
01:36:41,320 --> 01:36:42,880
THE BIOLOGICAL BASIS FOR WHY

2739
01:36:42,880 --> 01:36:44,240
INDIVIDUALS HAVE DIFFERENT

2740
01:36:44,240 --> 01:36:52,640
RESPONSES TO ENVIRONMENTAL

2741
01:36:52,640 --> 01:36:52,880
EXPOSURES.

2742
01:36:52,880 --> 01:36:54,840
SO I FIRST BECAME AWARE OF THIS

2743
01:36:54,840 --> 01:36:58,320
WHEN 3 OF OUR GRANTEES PRESENTED

2744
01:36:58,320 --> 01:37:00,440
THIS AT NIEH STHEY DESCRIBED

2745
01:37:00,440 --> 01:37:01,880
ENVIRONMENTAL HELT IT

2746
01:37:01,880 --> 01:37:02,960
DOVETAILSINIZELY WITH THE

2747
01:37:02,960 --> 01:37:03,640
PRECISION HEALTH PROGRAM WHICH I

2748
01:37:03,640 --> 01:37:06,680
THINK MANY OF YOU ARE AWARE.

2749
01:37:06,680 --> 01:37:09,400
IT'S PRECISION MEDICINE IS ABOUT

2750
01:37:09,400 --> 01:37:12,520
GENETIC VARIATIONS THAT CONFER

2751
01:37:12,520 --> 01:37:13,840
DIFFERENTIAL RESPONSES TO

2752
01:37:13,840 --> 01:37:16,160
MEDICAL TREATMENTS.

2753
01:37:16,160 --> 01:37:17,680
SO, THE NEW PROGRAM AND

2754
01:37:17,680 --> 01:37:19,360
POSSESSION OF VOIRMTAL HEALTH

2755
01:37:19,360 --> 01:37:21,520
INCLUDES THE ENVIRONMENTAL

2756
01:37:21,520 --> 01:37:22,680
EXPOSURES AND EPIGENETIC AND

2757
01:37:22,680 --> 01:37:24,280
VARIATIONS THAT CAN ARISE AS A

2758
01:37:24,280 --> 01:37:25,480
CONSEQUENCE OF THOSE

2759
01:37:25,480 --> 01:37:27,080
ENVIRONMENTAL EXPOSURES AND THE

2760
01:37:27,080 --> 01:37:28,480
FACT IS THAT THEY'RE

2761
01:37:28,480 --> 01:37:29,840
ENVIRONMENTAL EXPOSURES THAT

2762
01:37:29,840 --> 01:37:31,080
MAKE PEOPLE SICK, SO YOU HAVE TO

2763
01:37:31,080 --> 01:37:33,960
FACTOR THOSE INTO THE EQUATION.

2764
01:37:33,960 --> 01:37:35,680
SO THE PRECISION ENVIRONMENTAL

2765
01:37:35,680 --> 01:37:37,520
HEALTH IS REALLY ALL ABOUT

2766
01:37:37,520 --> 01:37:39,840
TRYING TO IDENTIFY THOSE GENETIC

2767
01:37:39,840 --> 01:37:40,960
AND GENOMIC SIGNALS THAT

2768
01:37:40,960 --> 01:37:43,480
REGULATE OUR GENES AND REGULATE

2769
01:37:43,480 --> 01:37:44,880
HOW OUR GENES ARE EXPRESSED

2770
01:37:44,880 --> 01:37:46,560
THROUGHOUT THE LIFE COURSE.

2771
01:37:46,560 --> 01:37:48,200
SO ANDREA, SHERYL AND DANA

2772
01:37:48,200 --> 01:37:50,640
EXPLAIN THAD THIS IS ALL ABOUT

2773
01:37:50,640 --> 01:37:53,440
UNDERSTANDING INDIVIDUAL RISK TO

2774
01:37:53,440 --> 01:37:54,320
PREVENT DISEASE.

2775
01:37:54,320 --> 01:37:56,120
SO IN A NUT SHELL PRECISION

2776
01:37:56,120 --> 01:37:57,200
ENVIRONMENTAL HEALTH IS WORKING

2777
01:37:57,200 --> 01:37:59,400
AT THE INTERSECTION OF PRECISION

2778
01:37:59,400 --> 01:38:00,400
GENETICS AND ENVIRONMENTAL

2779
01:38:00,400 --> 01:38:01,880
SCIENCE, DATA MANAGEMENT IS A

2780
01:38:01,880 --> 01:38:05,120
BIG PART OF PRECISION

2781
01:38:05,120 --> 01:38:07,200
ENVIRONMENTAL HEALTH AND IT ALSO

2782
01:38:07,200 --> 01:38:08,160
INCLUDES BETTER UNDERSTANDING

2783
01:38:08,160 --> 01:38:09,320
WHY WOMEN RESPOND TO THE

2784
01:38:09,320 --> 01:38:11,560
ENVIRONMENT IN DIFFERENT WAYS

2785
01:38:11,560 --> 01:38:12,040
THAN MEN.

2786
01:38:12,040 --> 01:38:16,200
SO LET'S GO TO THE NEXT SLIDE.

2787
01:38:16,200 --> 01:38:18,600
SO AS FAR AS THE ENVIRONMENTAL

2788
01:38:18,600 --> 01:38:19,440
COMPONENT TO PRECISION AND

2789
01:38:19,440 --> 01:38:20,720
ENVIRONMENTAL HEALTH IS

2790
01:38:20,720 --> 01:38:21,680
CONCERNED, THE ENVIRONMENTAL

2791
01:38:21,680 --> 01:38:22,800
HEALTH SCIENCES COMMUNITY HAS

2792
01:38:22,800 --> 01:38:25,440
COME TO RECOGNIZE THAT IF WE

2793
01:38:25,440 --> 01:38:26,880
TRULY WANT TO UNDERSTAND THE

2794
01:38:26,880 --> 01:38:28,000
IMPACT OF THE ENVIRONMENT WE

2795
01:38:28,000 --> 01:38:30,760
HAVE TO GET BEYOND STUDYING 1

2796
01:38:30,760 --> 01:38:31,880
EXPOSURE AT A TIME.

2797
01:38:31,880 --> 01:38:34,000
IT CAN'T BE JUST ABOUT AIR

2798
01:38:34,000 --> 01:38:35,120
POLLUTION OR IT CAPTAIN BE JUDGE

2799
01:38:35,120 --> 01:38:36,720
UOF THE ABOUT PESTICIDES BECAUSE

2800
01:38:36,720 --> 01:38:38,320
WE'RE EXPOSED TO ALL OF THESE

2801
01:38:38,320 --> 01:38:41,760
THINGS CONTINUOUSLY AND IT'S

2802
01:38:41,760 --> 01:38:43,560
THIS COLLECTIVE EXPOSURE THAT

2803
01:38:43,560 --> 01:38:45,040
ULTIMATELY IMPACTS HUMAN HEALTH.

2804
01:38:45,040 --> 01:38:46,280
SO THE COMMUNITY HAS EMBRACED

2805
01:38:46,280 --> 01:38:51,440
WHAT YOU SEE ON THE SLIDE IS

2806
01:38:51,440 --> 01:38:54,200
EMBRACED THE IT'S CALLED THE

2807
01:38:54,200 --> 01:38:56,400
EXPOSE OHM FRAMEWORK AND THIS IS

2808
01:38:56,400 --> 01:38:58,280
ABOUT STUDYING THE TOTALITY OF

2809
01:38:58,280 --> 01:38:59,240
EXPOSURES OVER A LIFETIME.

2810
01:38:59,240 --> 01:39:01,600
YOU CAN SEE THE SLIDE NOT ONLY

2811
01:39:01,600 --> 01:39:03,680
INVOLVES PHYSICAL AND CHEMICAL

2812
01:39:03,680 --> 01:39:05,280
AGENTS THAT CAN INFLUENCE HUMAN

2813
01:39:05,280 --> 01:39:07,680
HEALTH BUT ALSO INCLUDES DIET AS

2814
01:39:07,680 --> 01:39:10,280
I MENTIONED EARLIER,

2815
01:39:10,280 --> 01:39:11,760
PSYCHOSOPHISTICATED SOCIAL

2816
01:39:11,760 --> 01:39:12,720
STRESS, ECONOMIC STATUS, AND

2817
01:39:12,720 --> 01:39:13,880
ENVIRONMENT JUSTICE AND THE

2818
01:39:13,880 --> 01:39:16,800
IMPACTS OF THE BUILT

2819
01:39:16,800 --> 01:39:17,280
ENVIRONMENT.

2820
01:39:17,280 --> 01:39:20,600
TD EXPOSE OHM ALSO MEASURES

2821
01:39:20,600 --> 01:39:21,760
FISCAL ACTIVITY, SLEEP,

2822
01:39:21,760 --> 01:39:25,280
BEHAVIOR, DRUG AND HOLE USE, AND

2823
01:39:25,280 --> 01:39:25,960
ABUSE.

2824
01:39:25,960 --> 01:39:28,240
AND THE EXPOSEEM FRAMEWORK IS

2825
01:39:28,240 --> 01:39:29,720
ALL ABOUT INTEGRATING ALL OF

2826
01:39:29,720 --> 01:39:31,240
THESE REAL WORLD EXPOSE IRBURES

2827
01:39:31,240 --> 01:39:33,120
IN A WAY WE CAN TRULY UNDERSTAND

2828
01:39:33,120 --> 01:39:34,440
THE IMPACT OF THE TOTALITY OF

2829
01:39:34,440 --> 01:39:38,160
THE ENVIRONMENT AND TO DO THIS

2830
01:39:38,160 --> 01:39:39,680
OVER THE LIFE COURSE SO WHILE

2831
01:39:39,680 --> 01:39:42,680
MANY OF US HAVE BEEN USING THE

2832
01:39:42,680 --> 01:39:44,160
EXPOSE OHM TERMINOLOGY SINCE

2833
01:39:44,160 --> 01:39:46,120
2005 WHEN IT WAS FIRST PROPOSED

2834
01:39:46,120 --> 01:39:47,680
BY CHRIS WILD WAS BECOMING

2835
01:39:47,680 --> 01:39:49,440
INCREASINGLY CLEAR IS WE NEED A

2836
01:39:49,440 --> 01:39:51,080
BETTER UNDERSTANDING OF HOW DO

2837
01:39:51,080 --> 01:39:54,000
YOU DO AN EXPERIMENT, RECENTLY

2838
01:39:54,000 --> 01:39:55,240
DR. COLLINS, ASKED ME, HE WAS

2839
01:39:55,240 --> 01:39:57,160
INTERESTED AND RICK, HOW DO I DO

2840
01:39:57,160 --> 01:40:01,440
AN EXPO STUDIES OF MULTIPLE

2841
01:40:01,440 --> 01:40:01,920
ENDOCRINICS EXPERIENCE?

2842
01:40:01,920 --> 01:40:02,960
SO WHAT'S CLEAR IS THAT THE

2843
01:40:02,960 --> 01:40:05,160
COMMUNITY IS LACKING IN THE

2844
01:40:05,160 --> 01:40:07,800
CLEAR EXPERIMENTAL SIDE OF HOW

2845
01:40:07,800 --> 01:40:13,200
TO CONDUCT AN EXPERIMENT IN

2846
01:40:13,200 --> 01:40:13,920
EXPOETIC SOMMICS AND MANY

2847
01:40:13,920 --> 01:40:16,520
MEMBERS OF THE ENVIRONMENTAL

2848
01:40:16,520 --> 01:40:17,840
COMMUNITY HAVE RIVEN TO THE CHAL

2849
01:40:17,840 --> 01:40:19,160
ERVELG AND THE CHALLENGE WAS

2850
01:40:19,160 --> 01:40:23,560
SPECIFICALLY TO DEFINE HOW TO

2851
01:40:23,560 --> 01:40:25,200
OPERATIONALIZE EXPOSOMICs, SO

2852
01:40:25,200 --> 01:40:27,640
ALONG THESE LINES NIEHS PROVIDED

2853
01:40:27,640 --> 01:40:30,000
THIS COURSE OVER LAST SUMMER AND

2854
01:40:30,000 --> 01:40:31,600
HOPEFULLY SOME OF YOUR COMMUNITY

2855
01:40:31,600 --> 01:40:35,840
PARTICIPATED IN THESE, I HOPE,

2856
01:40:35,840 --> 01:40:39,080
AND THIS WAS ALL ABOUT MAKING

2857
01:40:39,080 --> 01:40:42,000
THE PIVOTAL SHIFT FROM EXPOSING

2858
01:40:42,000 --> 01:40:44,680
THE EXPOETIC SOM TO THE DATA, TO

2859
01:40:44,680 --> 01:40:45,960
THE TOTALITY OVER THE LIFE

2860
01:40:45,960 --> 01:40:48,440
COURSE, IT WAS ENCOURAGING, 400

2861
01:40:48,440 --> 01:40:49,480
COLLEAGUES ACROSS THE BIOMEDICAL

2862
01:40:49,480 --> 01:40:50,520
COMMUNITY WERE JOINING FOR SOME

2863
01:40:50,520 --> 01:40:52,120
OR ALL OF THESE WORKSHOPS AND

2864
01:40:52,120 --> 01:40:53,920
THERE WERE 64 TOPICS THAT WERE

2865
01:40:53,920 --> 01:40:54,960
RAISED AND DISCUSSED AND WE'RE

2866
01:40:54,960 --> 01:40:56,400
NOW AT THE POINT WHERE WE'RE

2867
01:40:56,400 --> 01:40:57,840
ADDRESSING 5 MAJOR TOPICS.

2868
01:40:57,840 --> 01:40:59,120
WHAT DO WE MEASURE?

2869
01:40:59,120 --> 01:41:00,560
HOW DO WE MEASURE IT, HOW TO

2870
01:41:00,560 --> 01:41:01,760
SHARE INTERNATIONAL

2871
01:41:01,760 --> 01:41:03,360
CLASSIFICATION GRIT, HARMONIZE,

2872
01:41:03,360 --> 01:41:05,000
ANALYZE AND AND INTERPRET THE

2873
01:41:05,000 --> 01:41:07,200
DATA AND HOW DO WE TRANSLATE

2874
01:41:07,200 --> 01:41:08,040
EXPOETIC STUDIES OF MULTIPLE

2875
01:41:08,040 --> 01:41:09,640
ENDOCRINICS DATA IN A WAY THAT

2876
01:41:09,640 --> 01:41:11,440
IT'S USEFUL AND CO MAKE AN

2877
01:41:11,440 --> 01:41:13,040
IMPACT AND STUDYING THE TOTALITY

2878
01:41:13,040 --> 01:41:18,560
OF EXPOSURES IN THE ENVIRONMENT.

2879
01:41:18,560 --> 01:41:20,160
SO STAY TUNED, I AM ENCOURAGED

2880
01:41:20,160 --> 01:41:22,880
WE MADE A LOT OF PROGRESS AND

2881
01:41:22,880 --> 01:41:24,240
OPERATIONAL MODEL FOR CONDUCTING

2882
01:41:24,240 --> 01:41:25,200
AN EXPOSE STUDIES OF MULTIPLE

2883
01:41:25,200 --> 01:41:26,120
ENDOCRINICS EXPERIMENT.

2884
01:41:26,120 --> 01:41:28,720
I KNOW DR. CRISWELL, ALSO

2885
01:41:28,720 --> 01:41:33,720
HAPPENS TO BE VERY ABOUTED IN

2886
01:41:33,720 --> 01:41:34,400
DOING EXPOSOMICs EXPERIMENTS

2887
01:41:34,400 --> 01:41:35,840
SO LET'S GO TO THE NEXT SLIDE,

2888
01:41:35,840 --> 01:41:37,480
NOW I'M GOING TO COVER A LOT SO

2889
01:41:37,480 --> 01:41:40,160
I WILL GIVE YOU A BROAD

2890
01:41:40,160 --> 01:41:41,720
FRAMEWORK FOR NIEHSRKS I

2891
01:41:41,720 --> 01:41:42,760
APOLOGIZE COVERING A LOT OF

2892
01:41:42,760 --> 01:41:43,640
INFORMATION IN A REEL KEEPSAKES

2893
01:41:43,640 --> 01:41:44,400
TELEVISIONALLY SHORT PERIOD OF

2894
01:41:44,400 --> 01:41:45,840
TIME BUT LET ME TRANSITION MORE

2895
01:41:45,840 --> 01:41:50,600
INTO THE WORK THAT WE DO IN

2896
01:41:50,600 --> 01:41:51,760
SUPPORTED OF WOMEN'S HEALTH.

2897
01:41:51,760 --> 01:41:53,680
SO WOMEN'S SHELGT A ESSENTIAL

2898
01:41:53,680 --> 01:41:54,720
COMPONENT OF THE RESEARCH WE DO

2899
01:41:54,720 --> 01:41:56,520
AND IT'S BEEN PART OF OUR AGENDA

2900
01:41:56,520 --> 01:41:59,760
FOR QUITE SOMETIME AND SO I

2901
01:41:59,760 --> 01:42:00,760
CAN'T GO THROUGH AND DESCRIBE

2902
01:42:00,760 --> 01:42:02,280
EVERYTHING THAT WE DO, IN

2903
01:42:02,280 --> 01:42:03,360
WOMEN'S HEALTH IN THE LIMITED

2904
01:42:03,360 --> 01:42:06,440
TIME THAT I HAVE TODAY, BUT

2905
01:42:06,440 --> 01:42:07,760
SUFFICE IT TO SAY THAT THE

2906
01:42:07,760 --> 01:42:10,200
RESEARCHERS WE SUPPORT IN OUR

2907
01:42:10,200 --> 01:42:11,600
INTRAMURAL AND EXTRAMURAL

2908
01:42:11,600 --> 01:42:13,120
COMMUNITIES APPLY THE BROAD

2909
01:42:13,120 --> 01:42:14,640
BASED APPROACHES THAT I DESCRIBE

2910
01:42:14,640 --> 01:42:20,680
AND THE PREVIOUS FEW SLIDES AND

2911
01:42:20,680 --> 01:42:22,280
THEY--THEY SPECIFICALLY USE THIS

2912
01:42:22,280 --> 01:42:23,560
APPROACH TO INVESTIGATE THE

2913
01:42:23,560 --> 01:42:25,880
ENVIRONMENTAL, THE LIFESTYLE AND

2914
01:42:25,880 --> 01:42:28,440
THE BEHAVIORIAL FACTORS THAT CAN

2915
01:42:28,440 --> 01:42:29,480
ULTIMATE INFLUENCE WHETHER WOMEN

2916
01:42:29,480 --> 01:42:30,840
WILL DEVELOP HEALTH PROBLEMS

2917
01:42:30,840 --> 01:42:31,720
OVER THEIR LIFE COURSE.

2918
01:42:31,720 --> 01:42:33,360
I MEAN THROUGH OUR PRECISION AND

2919
01:42:33,360 --> 01:42:34,960
ENVIRONMENTAL HEALTH PROGRAM, WE

2920
01:42:34,960 --> 01:42:37,120
STUDY GENETIC FACTORS, BUT WE

2921
01:42:37,120 --> 01:42:38,080
ALSO STUDIED CHEMICAL EXPOSURES

2922
01:42:38,080 --> 01:42:40,200
IN THE AIR, TO WATER, SIEL, FOOD

2923
01:42:40,200 --> 01:42:45,600
AND CONSUMER PRODUCTS THAT ARE

2924
01:42:45,600 --> 01:42:46,720
USED BY WOMEN.

2925
01:42:46,720 --> 01:42:48,560
AND WE'RE ULTIMATELY INTERESTED

2926
01:42:48,560 --> 01:42:50,440
IN CONTRIBUTING MORTALITY IN

2927
01:42:50,440 --> 01:42:51,520
WOMEN, SPECIFICALLY WE STUDY THE

2928
01:42:51,520 --> 01:42:53,040
ENVIRONMENTAL STRESSES THAT ARE

2929
01:42:53,040 --> 01:42:55,640
ASSOCIATED WITH UTERINE

2930
01:42:55,640 --> 01:42:56,920
FIBROIDS, INFERTILITY, INCREASED

2931
01:42:56,920 --> 01:43:00,400
RISK OF A VARIETY OF DIFFERENT

2932
01:43:00,400 --> 01:43:03,520
CANCERS, METABOLIC DISORDERS,

2933
01:43:03,520 --> 01:43:08,360
LACTATION DEFECTS, SEX

2934
01:43:08,360 --> 01:43:09,600
APPROPRIATE GONAD DEVELOPMENT

2935
01:43:09,600 --> 01:43:13,080
AND MAJOR STUDY ON IPPED O KRIN

2936
01:43:13,080 --> 01:43:14,040
DISRUPTION IN THE NATIONAL

2937
01:43:14,040 --> 01:43:15,200
TOXICOLOGY PROGRAM AND IT'S IA

2938
01:43:15,200 --> 01:43:17,080
BIG AREA OF FOCUS FOR MANY OF

2939
01:43:17,080 --> 01:43:20,320
THE GRAPTEES THAT WE SUPPORT ON

2940
01:43:20,320 --> 01:43:21,520
NIEHS, THERE'S CHEMICALS ARE

2941
01:43:21,520 --> 01:43:26,120
VERY IMPORTANT FACTOR IN

2942
01:43:26,120 --> 01:43:26,960
INFLUENCING WOMEN'S HEALTH.

2943
01:43:26,960 --> 01:43:29,960
SO WE ALSO SPRPT A VARIETY OF

2944
01:43:29,960 --> 01:43:32,080
PROJECTS AND THIS IS TRUE IN OUR

2945
01:43:32,080 --> 01:43:36,120
INTRAMURAL RESEARCH DIVISION, SO

2946
01:43:36,120 --> 01:43:38,120
WE'RE BASICALLY STUDYING THESE

2947
01:43:38,120 --> 01:43:39,400
FUNDAMENTAL AND BIOLOGICAL

2948
01:43:39,400 --> 01:43:41,440
PATHWAYS THAT DRIVE WOMEN'S

2949
01:43:41,440 --> 01:43:43,480
HEALTH AND REPRODUCTION, SO OUR

2950
01:43:43,480 --> 01:43:45,360
CLINICAL DIRECTOR DR. JAN HALL

2951
01:43:45,360 --> 01:43:46,240
STUDIES THE MECHANISMS INVOLVED

2952
01:43:46,240 --> 01:43:47,880
IN THE INTEGRATED CONTROL OF THE

2953
01:43:47,880 --> 01:43:48,920
REPRODUCT EVALUATION PROCESS

2954
01:43:48,920 --> 01:43:50,480
SYSTEM IN WOMEN AND IT'S

2955
01:43:50,480 --> 01:43:52,240
DISRUPTION IN REPROUCT DIDDIVE

2956
01:43:52,240 --> 01:43:53,400
DISORDERS, SO THE RESEARCH

2957
01:43:53,400 --> 01:43:55,440
FOCUSES ON THE NEURAL

2958
01:43:55,440 --> 01:43:56,880
INTERACTIONS THAT GOVERN--THAT

2959
01:43:56,880 --> 01:43:57,760
GOVERN NORMAL REPRODUCTION AND

2960
01:43:57,760 --> 01:43:59,440
THE CHANGES THAT OCCUR WITH

2961
01:43:59,440 --> 01:43:59,880
AGING.

2962
01:43:59,880 --> 01:44:01,000
AND IT'S ACTUALLY REALLY

2963
01:44:01,000 --> 01:44:01,840
FASCINATING SHE REEBTLY

2964
01:44:01,840 --> 01:44:03,240
DESCRIBED TO ME, A SET OF

2965
01:44:03,240 --> 01:44:07,680
EXPERIMENTS WHERE SHE'S LOOKING

2966
01:44:07,680 --> 01:44:09,520
AT HYPOTHALAMIC AMEN OREA, WHICH

2967
01:44:09,520 --> 01:44:11,640
IS A CONDITION OF LOSS OF

2968
01:44:11,640 --> 01:44:13,120
REPRODUCTIVE CYCLES IN OTHERWISE

2969
01:44:13,120 --> 01:44:14,280
NORMAL WITHEM WHICH IS

2970
01:44:14,280 --> 01:44:15,800
ASSOCIATED WITH INCREASED

2971
01:44:15,800 --> 01:44:23,520
EXERCISE OR DIETARY RESTRICTION.

2972
01:44:23,520 --> 01:44:26,040
WE HAVE A DOCTOR FOCUSING ON

2973
01:44:26,040 --> 01:44:28,520
FISCHERIOLOGY AND DISEASE AND

2974
01:44:28,520 --> 01:44:30,280
OVARIAN STEROIDS, PROGESTERONE

2975
01:44:30,280 --> 01:44:31,680
AND ESTROGEN.

2976
01:44:31,680 --> 01:44:34,520
AND DR. WILLIAMS STUDY MOLECULAR

2977
01:44:34,520 --> 01:44:36,080
EVENTS SPECIFICALLY HOW THE

2978
01:44:36,080 --> 01:44:37,760
EMBRYO DEVELOPS WITHIN THE FIRST

2979
01:44:37,760 --> 01:44:38,720
FEW DAYS OF LIFE.

2980
01:44:38,720 --> 01:44:40,720
SO THEY COULD GIVE YOU A LECTURE

2981
01:44:40,720 --> 01:44:42,960
ON ANY 1 OF THESE AREAS BUT VERY

2982
01:44:42,960 --> 01:44:46,960
EXCITING STUFF AND IT'S A MAJOR

2983
01:44:46,960 --> 01:44:49,960
FOCUS ON REALLY UNDERSTANDING

2984
01:44:49,960 --> 01:44:50,920
FEMALE PHYSIOLOGY, FEMALE

2985
01:44:50,920 --> 01:44:58,000
BIOLOGY AND IMPACT OF

2986
01:44:58,000 --> 01:45:07,840
ENVIRONMENTAL EPTION POSURES ON

2987
01:45:07,840 --> 01:45:09,680
FEMALE BIOLOGY, HOW STRUCTURAL

2988
01:45:09,680 --> 01:45:13,320
SOURCES AND THEY ALL EXACERBATE

2989
01:45:13,320 --> 01:45:18,920
MA TERRAL HEALTH.

2990
01:45:18,920 --> 01:45:20,760
SEE WE ALSO COME TO RECOGNIZE

2991
01:45:20,760 --> 01:45:22,520
THAT THERE ARE WINDOWS WHEN AN

2992
01:45:22,520 --> 01:45:23,720
INDIVIDUAL IS SENSITIVE TO

2993
01:45:23,720 --> 01:45:25,160
ENVIRONMENTAL EXPOSURES AND FROM

2994
01:45:25,160 --> 01:45:27,040
THE STANDPOINT OF WOMEN'S

2995
01:45:27,040 --> 01:45:28,640
HEALTH, PREGNANCY REPRESENTS A

2996
01:45:28,640 --> 01:45:29,600
SENSITIVE WINDOW OF

2997
01:45:29,600 --> 01:45:30,240
SUSCEPTIBILITY AND WE UNDERSTAND

2998
01:45:30,240 --> 01:45:34,760
THAT THIS IS A TIME WHEN IN

2999
01:45:34,760 --> 01:45:36,040
WOMEN THERE ARE PHYSIOLOGICAL

3000
01:45:36,040 --> 01:45:38,160
CHANGES TO EVERY MAJOR ORGAN

3001
01:45:38,160 --> 01:45:40,040
SYSTEM THAT INCREASE SENSITIVITY

3002
01:45:40,040 --> 01:45:41,200
TO ENVIRONMENTAL EXPOSURES SO

3003
01:45:41,200 --> 01:45:46,480
FOR EXAMPLE, HYPER TENSIVE

3004
01:45:46,480 --> 01:45:51,240
DISORDER IS 1 AND WE STUDY THOSE

3005
01:45:51,240 --> 01:45:52,320
FOR PREECLAMPSIA, CHRONIC

3006
01:45:52,320 --> 01:45:55,280
HYPERTENSION, THESE ARE ALL

3007
01:45:55,280 --> 01:45:56,720
LEADING CAUSES OF MATERNAL

3008
01:45:56,720 --> 01:45:57,640
MORBIDITY AND WE'RE ON TOP OF

3009
01:45:57,640 --> 01:45:57,920
IT.

3010
01:45:57,920 --> 01:46:00,000
SO THE DIVISION OF TRANSLATIONAL

3011
01:46:00,000 --> 01:46:01,200
TOXICOLOGY, WE RECENTLY CHANGED

3012
01:46:01,200 --> 01:46:04,600
THE NAME TO DTT, SO WE FOUND

3013
01:46:04,600 --> 01:46:06,400
THAT AIR POLLUTION FROM TRAFFIC

3014
01:46:06,400 --> 01:46:08,160
EMISSIONS FOR EXAMPLE ARE

3015
01:46:08,160 --> 01:46:09,440
PRESUMED HAZARD FOR HYPER

3016
01:46:09,440 --> 01:46:13,440
TENSIVE DISORDERS OF WOMEN.

3017
01:46:13,440 --> 01:46:16,080
AND OUR NIEHS GRANTEES

3018
01:46:16,080 --> 01:46:17,760
ESTABLISHED THAT THERE'S

3019
01:46:17,760 --> 01:46:19,640
EXPOSURE TO CAD METRICS UMKC AND

3020
01:46:19,640 --> 01:46:29,640
OTHER HEAVY MEDALS TO PFAS,

3021
01:46:29,640 --> 01:46:33,360
THALLATES AND ALSO PREGNANCY.

3022
01:46:33,360 --> 01:46:36,080
SO NIEHS SUPPORTED WORK THAT

3023
01:46:36,080 --> 01:46:38,600
FALLS IN THIS CONTEXT FALLING

3024
01:46:38,600 --> 01:46:41,000
BROADLY UNDER THIS DEFINITION OF

3025
01:46:41,000 --> 01:46:42,840
IT'S CALLED DOUGH HEAD WHICH

3026
01:46:42,840 --> 01:46:45,480
STANDS FOR THE DEVELOPMENTAL

3027
01:46:45,480 --> 01:46:47,080
ORIGINS OF HEALTH AND DISEASE.

3028
01:46:47,080 --> 01:46:49,680
SO YOU KNOW OF THE EPIDEMIOIO

3029
01:46:49,680 --> 01:46:51,480
LOGICAL SUPPORTS NOT SUPPORTED

3030
01:46:51,480 --> 01:46:54,040
BY NIEHS BUT WERE DONE TO

3031
01:46:54,040 --> 01:46:54,760
CONNECT STARVATION DURING

3032
01:46:54,760 --> 01:46:55,920
PREGNANCY WITH THE

3033
01:46:55,920 --> 01:46:57,520
PREDISPOSITION TO AN INCREASED

3034
01:46:57,520 --> 01:46:59,800
RISK OF OBESITY LATER IN LIFE,

3035
01:46:59,800 --> 01:47:02,600
IN THOSE--IN OFFSPRING AND MORE

3036
01:47:02,600 --> 01:47:04,800
RECENTLY NIEHS SUPPORTED

3037
01:47:04,800 --> 01:47:06,520
INVESTIGATORS, THAT ARE

3038
01:47:06,520 --> 01:47:09,440
DISCOVERING THAT THERE ARE

3039
01:47:09,440 --> 01:47:10,720
EXPOSURES DURING PREGNANCY THAT

3040
01:47:10,720 --> 01:47:12,640
CAN PREDISPOSE TO A WHOLE

3041
01:47:12,640 --> 01:47:13,600
VARIETY OF ADVERSE HEALTH

3042
01:47:13,600 --> 01:47:16,120
EFFECTS MUCH LATER IN LIFE.

3043
01:47:16,120 --> 01:47:18,400
SO, AND WE'VE ALSO FOUND THAT

3044
01:47:18,400 --> 01:47:20,480
EXPOWZURES DURING CHILDHOOD AND

3045
01:47:20,480 --> 01:47:21,640
EARLY PUBERTY REPRESENT ANOTHER

3046
01:47:21,640 --> 01:47:24,160
WINDOW OF CONCERN SINCE THESE

3047
01:47:24,160 --> 01:47:25,360
ARE WHENNED BODY IS GROWING

3048
01:47:25,360 --> 01:47:26,800
RAPIDLY AND THE HORMONE SYSTEMS

3049
01:47:26,800 --> 01:47:29,960
ARE ACTIVE AND THOSE

3050
01:47:29,960 --> 01:47:30,880
ENVIRONMENTAL EXPOSURES CAN HAVE

3051
01:47:30,880 --> 01:47:32,560
NEGATIVE I AM NOT PACTS ON THE

3052
01:47:32,560 --> 01:47:33,080
CHANGING BIOLOGY.

3053
01:47:33,080 --> 01:47:35,800
IN FACT IT GIVES ME A CHANCE TO

3054
01:47:35,800 --> 01:47:38,480
TALK ABOUT WORK IN MY OWN LAB

3055
01:47:38,480 --> 01:47:38,960
VERY BRIEFLY.

3056
01:47:38,960 --> 01:47:40,520
WE'VE ACTUALITILY BEEN STUDYING

3057
01:47:40,520 --> 01:47:43,440
HOW CHEMICAL EXPOSURES DURING

3058
01:47:43,440 --> 01:47:45,000
EARLY DEVELOPMENT CAN INFLUENCE

3059
01:47:45,000 --> 01:47:46,800
HOW GENES ARE EXPRESSED MUCH

3060
01:47:46,800 --> 01:47:48,840
LATER IN LIFE, AND SO WE TREATED

3061
01:47:48,840 --> 01:47:50,200
PREGNANT MICE WITH THE CHEMICAL

3062
01:47:50,200 --> 01:47:55,440
PEST SIDE CHA WE STUDIED AT

3063
01:47:55,440 --> 01:47:56,880
GREAT LENGTH IT'S A NATURAL

3064
01:47:56,880 --> 01:47:58,080
PESTICIDE AND IT'S THE TRONS

3065
01:47:58,080 --> 01:48:08,600
PORT CHAIN AND WE TREATED THE

3066
01:48:18,720 --> 01:48:19,400
PREGNANT THIS OCCURRED AT

3067
01:48:19,400 --> 01:48:20,920
WEANING AND WE STOPPED EXPOSURE

3068
01:48:20,920 --> 01:48:22,760
AT WEANING AND WE SAW THE

3069
01:48:22,760 --> 01:48:24,040
EFFECTS AT WEANING AND 6 MONTHS

3070
01:48:24,040 --> 01:48:26,440
OF AGE AND AT 12 AND 18 MONTHS

3071
01:48:26,440 --> 01:48:27,040
OF AGE.

3072
01:48:27,040 --> 01:48:29,560
SO IT WAS WELL AFTER I MEAN

3073
01:48:29,560 --> 01:48:33,080
MONTHS AFTER THE EXPOSURE WAS

3074
01:48:33,080 --> 01:48:34,320
DONE.

3075
01:48:34,320 --> 01:48:35,640
SO THESE EPIGENETIC MODIFICATION

3076
01:48:35,640 --> 01:48:38,080
SAYS HAD THE POTENTIAL TO IMPACT

3077
01:48:38,080 --> 01:48:39,840
THE WHOLE SERIES OF NETWORKS

3078
01:48:39,840 --> 01:48:43,960
FROM MAP KINASE SIGNALING TO

3079
01:48:43,960 --> 01:48:44,760
HEPATOCELLULAR CARCINOMA SO THE

3080
01:48:44,760 --> 01:48:46,600
BOTTOM LINE IS THAT DEVELOPMENT

3081
01:48:46,600 --> 01:48:48,800
IS A HIGHLY SUSCEPTIBLE WINDOW

3082
01:48:48,800 --> 01:48:50,200
AND ENVIRONMENTAL EXPOSURES

3083
01:48:50,200 --> 01:48:51,680
DURING DIFFERENT WINDOWS CAN

3084
01:48:51,680 --> 01:48:53,160
CAUSE YOUR GENES TO MISBEHAVE

3085
01:48:53,160 --> 01:48:55,920
AND NOT OHM DURING TWEPMENT, BUT

3086
01:48:55,920 --> 01:48:58,800
ALSO MUCH, MUCH, LATER IN LIFE

3087
01:48:58,800 --> 01:48:59,600
THROUGH THESE EPIGENETIC

3088
01:48:59,600 --> 01:49:01,040
MECHANICANISMS SO IT'S A VERY

3089
01:49:01,040 --> 01:49:05,560
IMPORTANT AREA OF FOCUS FOR

3090
01:49:05,560 --> 01:49:05,800
NIEHS.

3091
01:49:05,800 --> 01:49:08,520
AND I WOULD SAY FOR A BROAD BASE

3092
01:49:08,520 --> 01:49:09,240
OF COMMUNITY THESE DAYS.

3093
01:49:09,240 --> 01:49:10,680
WELL THE'S GO TO THE NEXT SLIDE.

3094
01:49:10,680 --> 01:49:11,440
SO I ALSO WANT TO INCREASE THE

3095
01:49:11,440 --> 01:49:14,440
NUMBER OF EXAMS OUT THERE OUR

3096
01:49:14,440 --> 01:49:16,200
FOCUS ON ENVIRONMENTAL JUDGE

3097
01:49:16,200 --> 01:49:19,240
JUSTICE THAT WE'RE STUDYING HOW

3098
01:49:19,240 --> 01:49:19,880
ADVERSE ENVIRONMENTAL EXPOSURES

3099
01:49:19,880 --> 01:49:21,360
LIKELY CONTRIBUTE TO THE HEALTH

3100
01:49:21,360 --> 01:49:23,200
DISPARITIES ASSOCIATE WIDE THE

3101
01:49:23,200 --> 01:49:24,640
MORBIDITY AND MORTALITY OF

3102
01:49:24,640 --> 01:49:25,120
MINORITY POPULATIONS.

3103
01:49:25,120 --> 01:49:28,840
SO I BELIEVE WE ALL KNOW THAT

3104
01:49:28,840 --> 01:49:30,200
CHEMICAL AND NONCHEMICAL

3105
01:49:30,200 --> 01:49:31,280
EXPOSURES THAT ADVERSELY WOMEN'S

3106
01:49:31,280 --> 01:49:32,960
HEALTH ARE NOT RANDOMLY

3107
01:49:32,960 --> 01:49:34,080
DISTRIBUTED ACROSS THE

3108
01:49:34,080 --> 01:49:34,480
POPULATION.

3109
01:49:34,480 --> 01:49:36,080
SO MOST RACIAL AND ETHNIC

3110
01:49:36,080 --> 01:49:37,360
MINORITIES LIVE IN LARGELY

3111
01:49:37,360 --> 01:49:38,640
DIFFERENT PHYSICAL AND SOCIAL

3112
01:49:38,640 --> 01:49:41,280
ENVIRONMENTS COMPARED TO THE

3113
01:49:41,280 --> 01:49:43,000
MAJORITY WIDE POPULATION AND

3114
01:49:43,000 --> 01:49:44,960
INVESTIGATORS SUPPORTED BY NIEHS

3115
01:49:44,960 --> 01:49:45,920
DISCOVERED THAT RACIAL

3116
01:49:45,920 --> 01:49:47,360
DIFFERENCES AND EXPOSSESSURE TO

3117
01:49:47,360 --> 01:49:48,680
ENVIRONMENTAL STRESSORS LEAD TO

3118
01:49:48,680 --> 01:49:59,160
DIFFERENTIAL RISK ACROSS THE

3119
01:50:07,160 --> 01:50:07,880
LIFE SPAN.

3120
01:50:07,880 --> 01:50:10,680
--SO RECENTLY AS YOU CAN SEE ON

3121
01:50:10,680 --> 01:50:13,080
SLIDE, WE RECENTLY HAD A

3122
01:50:13,080 --> 01:50:13,720
WORKSHOP ENTITLED ENVIRONMENTAL

3123
01:50:13,720 --> 01:50:16,720
IMPACTS ON WOMEN'S HEALTH

3124
01:50:16,720 --> 01:50:17,720
DISPARITIES AND PREPRODUCTIVE

3125
01:50:17,720 --> 01:50:19,720
HEALTH AND WE LEARNED THAT WE

3126
01:50:19,720 --> 01:50:21,280
NEED TO CREATE EQUAL ACCESS TO

3127
01:50:21,280 --> 01:50:22,520
TOOLS AND OPPORTUNITIES TO

3128
01:50:22,520 --> 01:50:23,600
IMPROVE HEALTH EQUITY AND WE

3129
01:50:23,600 --> 01:50:25,440
ALSO LEARNED THAT WE NEED TO

3130
01:50:25,440 --> 01:50:28,280
SHIFT TO TRANSAALATIONAL AND

3131
01:50:28,280 --> 01:50:29,000
ENVIRONMENTAL EPIDEMIOLOGIC

3132
01:50:29,000 --> 01:50:31,440
RESEARCH FRAMEWORKS WE NEED TO

3133
01:50:31,440 --> 01:50:32,360
DEVELOP TRANSDISCIPLINARY

3134
01:50:32,360 --> 01:50:33,760
COMMUNITY DRIIVE AND

3135
01:50:33,760 --> 01:50:34,560
COMPREHENSIVE RESEARCH PROGRAMS

3136
01:50:34,560 --> 01:50:37,360
THAT LEAD TO ACTION AND TO

3137
01:50:37,360 --> 01:50:38,120
INFORMED POLICY AND INTEGRATED

3138
01:50:38,120 --> 01:50:39,160
OF COURSE IS LEARNING HOW TO

3139
01:50:39,160 --> 01:50:46,040
TALK ABOUT THE WORK THAT WE DO

3140
01:50:46,040 --> 01:50:48,240
AND SO THAT THEY UNDERSTAND THE

3141
01:50:48,240 --> 01:50:48,920
WORK WE'RE CONDUCTING.

3142
01:50:48,920 --> 01:50:49,360
NEXT SLIDE, PLEASE.

3143
01:50:49,360 --> 01:50:55,920
AND AS I MENTIONED

3144
01:50:55,920 --> 01:50:58,080
DR. [INDISCERNIBLE] AT NIEHS HAS

3145
01:50:58,080 --> 01:50:59,760
DONE REMARKABLE WORK TO SPONSOR

3146
01:50:59,760 --> 01:51:01,200
WORKSHOPS TO IMPLEMENT WORKSHOPS

3147
01:51:01,200 --> 01:51:02,160
TO DISTEMINATE KNOWLEDGE ON

3148
01:51:02,160 --> 01:51:03,560
WOMEN'S HEALTH INTO THE

3149
01:51:03,560 --> 01:51:03,800
COMMUNITY.

3150
01:51:03,800 --> 01:51:05,840
ESPECIALLY COMMUNITIES OF COLOR.

3151
01:51:05,840 --> 01:51:11,280
SO THIS IS IN SUPPORT OF OUR

3152
01:51:11,280 --> 01:51:13,560
SECOND THEM OF OUR PLAN AND

3153
01:51:13,560 --> 01:51:15,520
HAVING IMPACT ON THE PUBLIC

3154
01:51:15,520 --> 01:51:17,360
HEALTH SO DR. CANNED WHAT

3155
01:51:17,360 --> 01:51:20,040
MANAGES THE WOMEN'S HEALTH

3156
01:51:20,040 --> 01:51:21,440
AWARENESS INITIATIVE AT NIEHS

3157
01:51:21,440 --> 01:51:22,760
AND AS YOU CAN SEE ON THIS

3158
01:51:22,760 --> 01:51:24,520
SLIDE, IT HAS A MISSION TO

3159
01:51:24,520 --> 01:51:26,040
INFORM AND EMPOWER WOMEN TO TAKE

3160
01:51:26,040 --> 01:51:27,320
RESPONSIBILITY FOR THEIR HEALTH,

3161
01:51:27,320 --> 01:51:28,480
TO UNDERSTAND THEIR HEALTH

3162
01:51:28,480 --> 01:51:33,040
OPTIONS AND TO IDENTIFY SERVICES

3163
01:51:33,040 --> 01:51:34,440
THEREBY INCREASING ACCESS TO

3164
01:51:34,440 --> 01:51:35,320
SERVICES, RESOURCES AND PRODUCTS

3165
01:51:35,320 --> 01:51:38,440
THAT BEST HELP THEM PREVENT AND

3166
01:51:38,440 --> 01:51:39,800
REDUCE POOR HEALTH.

3167
01:51:39,800 --> 01:51:45,680
SO THIS INITIATIVE BRINGS

3168
01:51:45,680 --> 01:51:46,320
EDUCATION ENVIRONMENTAL HEALTH

3169
01:51:46,320 --> 01:51:47,240
LITERACY TO THE WOMEN ACROSS

3170
01:51:47,240 --> 01:51:49,360
NORTH CAROLINA FOR THE PURPOSE

3171
01:51:49,360 --> 01:51:52,440
OF PROMOTING HEALTHIER LIVES BY

3172
01:51:52,440 --> 01:51:53,680
PROMOTING AWARENESS OF

3173
01:51:53,680 --> 01:51:54,680
ENVIRONMENTAL SAFER HOMES AND

3174
01:51:54,680 --> 01:51:54,920
COMMUNITY.

3175
01:51:54,920 --> 01:51:56,520
SO I ALMS WANT TO POINT OUT THAT

3176
01:51:56,520 --> 01:51:58,680
JOAN IS MANAGING A PROJECT

3177
01:51:58,680 --> 01:52:00,840
CALLED WOMEN'S HEALTH AWARENESS,

3178
01:52:00,840 --> 01:52:05,480
COMMUNITY RESILIENCY AND

3179
01:52:05,480 --> 01:52:07,240
ENVIRONMENTAL ACTION AND

3180
01:52:07,240 --> 01:52:11,640
COLLABORATIONS FOR HEALTH, IT'S

3181
01:52:11,640 --> 01:52:15,640
CALLED THE REACH EQUITY PROGRAM.

3182
01:52:15,640 --> 01:52:17,280
IT'S TO IDENTIFY PREDISPOSING

3183
01:52:17,280 --> 01:52:20,960
FACTORS AND COVID-19 RELATED

3184
01:52:20,960 --> 01:52:22,480
FACTORS IN WOMEN WITH THEIR

3185
01:52:22,480 --> 01:52:22,760
FAMILIES.

3186
01:52:22,760 --> 01:52:26,840
SO THE OVERALL GOAL SPECIAL TO

3187
01:52:26,840 --> 01:52:27,760
DEVELOP PREVENTIONS WITH DISEASE

3188
01:52:27,760 --> 01:52:29,840
PREVENTION, CONTROL AND

3189
01:52:29,840 --> 01:52:32,160
MANAGEMENT FOR DISEASE RECOVER

3190
01:52:32,160 --> 01:52:33,280
EXPE UNDERREPORPTED AND

3191
01:52:33,280 --> 01:52:39,560
UNDERSTUDIED WOMEN POST

3192
01:52:39,560 --> 01:52:39,960
COVID-19.

3193
01:52:39,960 --> 01:52:42,920
SO I WILL NOTE THE PROJECTS SO

3194
01:52:42,920 --> 01:52:44,000
DR. CLAYTON WE SPREESHT THE

3195
01:52:44,000 --> 01:52:45,000
COSPONSORSHIP OF THIS PROGRAM.

3196
01:52:45,000 --> 01:52:46,280
I LOOK FORWARD, I UPON IS YOU

3197
01:52:46,280 --> 01:52:47,840
LOOK FORWARD ALSO TO THE VERY

3198
01:52:47,840 --> 01:52:48,680
EXCITING RESULTS THAT WILL BE

3199
01:52:48,680 --> 01:52:59,160
COMING OUT OF THIS PROGRAM.

3200
01:53:05,760 --> 01:53:06,880
SO BEFORE I CONTINUE, I WANT TO

3201
01:53:06,880 --> 01:53:08,200
HEAR MORE ABOUT THE WORK THAT'S

3202
01:53:08,200 --> 01:53:10,560
BEING DONE IN THE VEERMTAL

3203
01:53:10,560 --> 01:53:13,280
HEALTH SCIENCES BY DRS. SANDLER,

3204
01:53:13,280 --> 01:53:14,360
HARMON AND UPSON, AND I THINK

3205
01:53:14,360 --> 01:53:16,080
THAT WILL HAPPEN LATER ON TODAY,

3206
01:53:16,080 --> 01:53:19,240
IT'S PART OF A PANEL DISCUSSION

3207
01:53:19,240 --> 01:53:21,240
OR PANEL PRESENTATION ENTITLED

3208
01:53:21,240 --> 01:53:22,400
EPIDEMIOLOGIC CONTRIBUTIONS TO

3209
01:53:22,400 --> 01:53:23,440
UNDERSTANDING THE ENVIRONMENTAL

3210
01:53:23,440 --> 01:53:28,200
IMPACTS ON WOMEN'S HEALTH.

3211
01:53:28,200 --> 01:53:29,920
SO DR. CHRISTEN UPSON IS 1 OF

3212
01:53:29,920 --> 01:53:32,200
OUR POST DOCTORAL FELLOWS AT

3213
01:53:32,200 --> 01:53:35,840
NIEHS, SHE IS A PROFESSOR OF

3214
01:53:35,840 --> 01:53:36,640
EMDEEMIOLOGY AND BIOSTATISTICS

3215
01:53:36,640 --> 01:53:38,040
AT MICHIGAN STATE AND SHE WILL

3216
01:53:38,040 --> 01:53:39,600
DESCRIBE HER WORK ON STUDYING

3217
01:53:39,600 --> 01:53:42,760
FACTORS THAT INFLUENCE THE RISK

3218
01:53:42,760 --> 01:53:44,360
OF DEVELOPING ENDOMETRIOSIS, SO

3219
01:53:44,360 --> 01:53:47,600
SHE IS USING THE WREN COHORT AND

3220
01:53:47,600 --> 01:53:50,000
WILL SHOW HOW ORGAN O CHLORINE

3221
01:53:50,000 --> 01:53:54,200
PEST TIDES PC Bs, THALLATES

3222
01:53:54,200 --> 01:53:57,160
AND BPA AND SOY IN FORMULA

3223
01:53:57,160 --> 01:54:01,200
FEEDING AS WELL AS DEHS AND

3224
01:54:01,200 --> 01:54:02,640
DEVELOP ENDOMEET RIONOSEIS.

3225
01:54:02,640 --> 01:54:04,560
AND DR. QUAKER HARMON IS AN

3226
01:54:04,560 --> 01:54:06,080
INVESTIGATOR IN OUR DIVISION OF

3227
01:54:06,080 --> 01:54:06,840
INTRAMURAL RESEARCH.

3228
01:54:06,840 --> 01:54:07,800
SHE WILL DISCUSS THE WORK SHE'S

3229
01:54:07,800 --> 01:54:11,000
BEEN DOING ON THE SELF-COHORT

3230
01:54:11,000 --> 01:54:15,360
HAD IS A COLLECTION OF ABOUT

3231
01:54:15,360 --> 01:54:17,360
1693 WOMEN WHO SELF-IDENTIFIED

3232
01:54:17,360 --> 01:54:19,120
AS BLACK OR AFRICAN AMERICAN,

3233
01:54:19,120 --> 01:54:21,200
AGES 23-35 FROM THE DETROIT

3234
01:54:21,200 --> 01:54:23,640
MICHIGAN AREA. 

3235
01:54:23,640 --> 01:54:25,320
SO SHE'S USING THE TO HOTTER TO

3236
01:54:25,320 --> 01:54:26,600
STUDY THE ENVIRONMENTAL LIFE

3237
01:54:26,600 --> 01:54:28,480
SOMETIME FACTORS THAT INFLUENCE

3238
01:54:28,480 --> 01:54:31,240
THE DEVELOPMENT OF UTERINE

3239
01:54:31,240 --> 01:54:32,480
FIBROIDS.

3240
01:54:32,480 --> 01:54:34,880
AS YOU PROBABLY KNOW UTERINE

3241
01:54:34,880 --> 01:54:37,280
FOOTBALL ROADWAYS ARE HORMONAL

3242
01:54:37,280 --> 01:54:39,360
BENIGN TUMORS IN THE MUSCLE AND

3243
01:54:39,360 --> 01:54:40,400
THEY DEVELOP IN PREMENSTRUAL

3244
01:54:40,400 --> 01:54:44,280
WOMEN SO THEY ARE THE LEADING

3245
01:54:44,280 --> 01:54:45,000
INDICATION FOR--SORRY

3246
01:54:45,000 --> 01:54:45,440
PREMENOPAUSAL WOMEN.

3247
01:54:45,440 --> 01:54:46,720
OKAY THAT MAKES A LOT MORE

3248
01:54:46,720 --> 01:54:57,240
SENSE, SO THEY'RE THE LEADING

3249
01:54:58,800 --> 01:55:00,000
INDICATION FOR UTERINE FIBROIDS

3250
01:55:00,000 --> 01:55:04,440
AND SHE IS WORKING ON MED

3251
01:55:04,440 --> 01:55:06,360
KAILINGSS FOR THIS CONDITION.

3252
01:55:06,360 --> 01:55:10,080
AND FINALLY DR. DALE SANDLER

3253
01:55:10,080 --> 01:55:11,560
WILL WORK ON THE REMARK

3254
01:55:11,560 --> 01:55:12,600
ALGORITHMS SISTER STUDY.

3255
01:55:12,600 --> 01:55:13,800
SHE WILL TELL YOU A LOT MORE

3256
01:55:13,800 --> 01:55:14,160
ABOUT THIS.

3257
01:55:14,160 --> 01:55:16,280
SO IT'S A COHORT OF ABOUT 50,000

3258
01:55:16,280 --> 01:55:18,440
WOMEN FROM ACROSS THE UNITED

3259
01:55:18,440 --> 01:55:19,920
STATES AND PUERTO RICO WHO WERE

3260
01:55:19,920 --> 01:55:24,160
BETWEEN THE AGES OF 35-74 AND

3261
01:55:24,160 --> 01:55:26,960
WHOSE SISTER HAD BREAST CANCER.

3262
01:55:26,960 --> 01:55:29,120
AND BECAUSE OF THEIR SHARED

3263
01:55:29,120 --> 01:55:30,400
ENVIRONMENT, GENES AND

3264
01:55:30,400 --> 01:55:31,640
EXPERIENCES DR. SANDLER AND HER

3265
01:55:31,640 --> 01:55:33,160
COLLEAGUES FOUND THAT STUDYING

3266
01:55:33,160 --> 01:55:34,400
SISTERS PROVIDES A GREATER

3267
01:55:34,400 --> 01:55:37,080
CHANCE OF TEASING OUT THOSE RISK

3268
01:55:37,080 --> 01:55:38,000
FACTORS THAT PREDISPOSE TO

3269
01:55:38,000 --> 01:55:38,520
BREAST CANCER.

3270
01:55:38,520 --> 01:55:40,600
SO THEY'VE BEEN ABLE TO USE THIS

3271
01:55:40,600 --> 01:55:42,920
UNIQUE COHORT TO STUDY THE

3272
01:55:42,920 --> 01:55:43,480
ENVIRONMENTAL AND EPIGENIC

3273
01:55:43,480 --> 01:55:45,040
FACTORS AND THE DEVELOPMENT OF

3274
01:55:45,040 --> 01:55:47,040
BREAST CANCER AS WELL AS A

3275
01:55:47,040 --> 01:55:48,080
NUMBER OF OTHER ADVERSE HEALTH

3276
01:55:48,080 --> 01:55:52,840
EFFECTS SO I'M SURE YOU WILL BE

3277
01:55:52,840 --> 01:55:54,720
VERY GOD IN HEARING FROM THESE 3

3278
01:55:54,720 --> 01:55:55,560
DIFFERENT INVESTIGATORS.

3279
01:55:55,560 --> 01:56:06,120
SO LET'S MOVE TO THE NEXT SLIDE.

3280
01:56:07,200 --> 01:56:09,240
LET ME SET THE STAGE THR THIS

3281
01:56:09,240 --> 01:56:11,160
DISCUSSION IN THE CLIMATE CHANGE

3282
01:56:11,160 --> 01:56:11,840
FOR WOMEN'S HEALTH.

3283
01:56:11,840 --> 01:56:13,440
AND TO ADDRESS THIS I WANT TO

3284
01:56:13,440 --> 01:56:15,160
REFERENCE THE UN SECRETARY

3285
01:56:15,160 --> 01:56:16,680
GENERAL WHO SAID WE'RE

3286
01:56:16,680 --> 01:56:18,440
EXPERIENCING CODE RED FOR

3287
01:56:18,440 --> 01:56:18,880
HUMANITY.

3288
01:56:18,880 --> 01:56:20,760
SO CLIMATE CHANGE EXACERBATES

3289
01:56:20,760 --> 01:56:22,720
CHRONIC AND CONTAGIOUS DISEASE

3290
01:56:22,720 --> 01:56:24,280
AND WORSENS FOOD AND WATER

3291
01:56:24,280 --> 01:56:26,920
SHORTAGES AND INCREASES THE RISK

3292
01:56:26,920 --> 01:56:28,640
OF PANDEMICS AND AGGRAVATES MASS

3293
01:56:28,640 --> 01:56:30,280
DISPLACEMENT AND WE'RE SEEING

3294
01:56:30,280 --> 01:56:32,480
INCREASED SEVERITY AND FREQUENCY

3295
01:56:32,480 --> 01:56:33,840
OF WEATHER RELATED DISASTERS

3296
01:56:33,840 --> 01:56:35,680
COSTING OVER A BILLION DOLLARS,

3297
01:56:35,680 --> 01:56:38,440
IN 2020 ALONE WE SAW 22 SUCH

3298
01:56:38,440 --> 01:56:41,160
EVENTS COSTING A TOTAL OF 450

3299
01:56:41,160 --> 01:56:42,160
BILL WHEREON AND GOD ONLY KNOWS

3300
01:56:42,160 --> 01:56:44,720
WHAT IT WILL BE WITH THE RECENT

3301
01:56:44,720 --> 01:56:47,600
DISASTERS IN PUERTO RICO AND

3302
01:56:47,600 --> 01:56:48,680
FLORIDA WITH HURRICANE IAN.

3303
01:56:48,680 --> 01:56:50,160
SO WHILE IT'S CLEAR WE ARE AT A

3304
01:56:50,160 --> 01:56:51,720
POINT WHERE WE NEED TO BETTER

3305
01:56:51,720 --> 01:56:58,600
UNDERSTAND THE LONG IMPACTS OF

3306
01:56:58,600 --> 01:57:00,240
CLIMATE CHANGE WE ALSO NEED TO

3307
01:57:00,240 --> 01:57:01,720
UNDERSTAND THE HEALTH IMPACTS

3308
01:57:01,720 --> 01:57:04,640
WITH THESE SEVERE WEATHER

3309
01:57:04,640 --> 01:57:14,440
EEIVETS.

3310
01:57:14,440 --> 01:57:15,640
NEXT SLIDE.

3311
01:57:15,640 --> 01:57:18,640
SO LET SEA SEE CLICK PLIES, SO

3312
01:57:18,640 --> 01:57:20,120
CLIMATE CHANGE RESULTS IN

3313
01:57:20,120 --> 01:57:20,800
INCREASED GLOBAL TEMPERATURE AS

3314
01:57:20,800 --> 01:57:23,040
YOU CAN SEE ON THE SLIDE,

3315
01:57:23,040 --> 01:57:25,080
EXTREME WEATHER EVENTS

3316
01:57:25,080 --> 01:57:25,680
PRECIPITATION EXTREMES, SEA

3317
01:57:25,680 --> 01:57:27,680
LEVEL RISE AND CHANGES IN LAND

3318
01:57:27,680 --> 01:57:27,840
USE.

3319
01:57:27,840 --> 01:57:38,360
SO CLICK AGAIN PLEASE, THERE WE

3320
01:57:38,960 --> 01:57:39,760
ARE.

3321
01:57:39,760 --> 01:57:41,320
REDUCED FOOD AND WATER QUALITY

3322
01:57:41,320 --> 01:57:49,360
AND INCHANGE IN DISEASE AND SO

3323
01:57:49,360 --> 01:57:54,240
THESE RELATE IN HEAT RELATED

3324
01:57:54,240 --> 01:57:55,640
ILILLUMINATENESS, CARDIOVASCULAR

3325
01:57:55,640 --> 01:57:56,840
DISEASE, OTHER CHRONIC

3326
01:57:56,840 --> 01:57:57,880
CONDITIONS AND DEATH.

3327
01:57:57,880 --> 01:58:01,520
THEY ALSO RESULT IN NEUROLOGICAL

3328
01:58:01,520 --> 01:58:03,120
DISORDERS, VECTOR BORNE DISEASE

3329
01:58:03,120 --> 01:58:04,120
AND RESPIRATORY DISEASE AND

3330
01:58:04,120 --> 01:58:04,560
ASTHMA.

3331
01:58:04,560 --> 01:58:05,320
SO NEXT SLIDE.

3332
01:58:05,320 --> 01:58:06,920
HERE WE ARE, SUBMITTING THE

3333
01:58:06,920 --> 01:58:08,440
HEALTH EFFECTS THAT I JUST

3334
01:58:08,440 --> 01:58:10,640
DESCRIBED FALL GENERALLY INTO

3335
01:58:10,640 --> 01:58:11,920
THE CATEGORY OF DIRECT EFFECTS

3336
01:58:11,920 --> 01:58:13,200
BUT IT'S REALLY IMPORTANT TO

3337
01:58:13,200 --> 01:58:14,760
RECOGNIZE THAT THERE ARE ALSO

3338
01:58:14,760 --> 01:58:16,400
MANY INDIRECT EFFECTS OF CLIMATE

3339
01:58:16,400 --> 01:58:26,040
CHANGE ON HUMAN HEALTH.

3340
01:58:26,040 --> 01:58:26,800
THROUGH POPULATION DISPLACEMENT,

3341
01:58:26,800 --> 01:58:28,880
CHAIMPLES IN AIR, WATER, FOOD,

3342
01:58:28,880 --> 01:58:31,160
QUALITY, AND QUANTITY,

3343
01:58:31,160 --> 01:58:32,960
POPULATIONS DISPLACEMENT ISSUES

3344
01:58:32,960 --> 01:58:34,160
INTERRUPTIONS TO HEALTHCARE,

3345
01:58:34,160 --> 01:58:35,360
DISRUPTIONS TO THE

3346
01:58:35,360 --> 01:58:36,520
INFRASTRUCTURE AND SUPPLY CHAIN

3347
01:58:36,520 --> 01:58:37,720
FOR HEALTHCARE THEREFOREY AS

3348
01:58:37,720 --> 01:58:39,160
WELL AS ECONOMIC IMPACTS, FOR

3349
01:58:39,160 --> 01:58:40,000
EXAMPLE, MORE PEOPLE ARE GOING

3350
01:58:40,000 --> 01:58:46,680
TO BE LIVING IN POVERTY AS A

3351
01:58:46,680 --> 01:58:48,040
CONSEQUENCE OF CLIMATE CHANGE.

3352
01:58:48,040 --> 01:58:48,360
NEXT SLIDE.

3353
01:58:48,360 --> 01:58:50,840
I ALSO WANT TO STATE RIGHT UP

3354
01:58:50,840 --> 01:58:52,800
FRONT THAT WE RECOGNIZE THAT THE

3355
01:58:52,800 --> 01:58:55,480
HEALTH IMPACTS OF CLIMATE CHANGE

3356
01:58:55,480 --> 01:58:57,880
ARE DISPROPORTIONATELY BORNE BY

3357
01:58:57,880 --> 01:59:00,760
THE MOST VULNERABLE AMERICANS

3358
01:59:00,760 --> 01:59:03,480
AND WOULD INCLUDE DISPARITIES,

3359
01:59:03,480 --> 01:59:04,880
EXPOSED WORKERS, PERSONS WITH

3360
01:59:04,880 --> 01:59:06,160
DISABILITIES THOSE WHO ARE

3361
01:59:06,160 --> 01:59:09,680
VULNERABLE BY LIFE STAGE, FOR

3362
01:59:09,680 --> 01:59:10,720
EXAMPLE DURING PREGNANCY OR

3363
01:59:10,720 --> 01:59:12,000
MEDICAL CONDITIONS AND IT'S ALSO

3364
01:59:12,000 --> 01:59:13,800
CLEAR THAT POPULATIONS IN LOW

3365
01:59:13,800 --> 01:59:14,960
AND MIDDLE INCOME COUNTRIES WITH

3366
01:59:14,960 --> 01:59:16,880
HIGHER RATES OF EXISTING

3367
01:59:16,880 --> 01:59:18,840
DISEASES, NUTRITION AND EXTREME

3368
01:59:18,840 --> 01:59:20,840
POVERTY ARE ALSO

3369
01:59:20,840 --> 01:59:21,760
DISPROPORTIONATELY IMPACTED BY

3370
01:59:21,760 --> 01:59:29,200
CLIMATE CHANGE.

3371
01:59:29,200 --> 01:59:30,480
NEXT SLIDE.

3372
01:59:30,480 --> 01:59:31,680
SO THERE AIAN LOT ON THIS SLIDE

3373
01:59:31,680 --> 01:59:34,600
BUT I WANT TO FOCUS ON THE FACT

3374
01:59:34,600 --> 01:59:36,160
THAT CLIMATE CHANGE AFFECTS

3375
01:59:36,160 --> 01:59:36,600
WOMEN DIFFERENTLY.

3376
01:59:36,600 --> 01:59:38,040
BUT I WILL COMMENT ON THOSE IN A

3377
01:59:38,040 --> 01:59:41,120
MINUTE BUT YOU WITH SEE ON THE

3378
01:59:41,120 --> 01:59:42,760
SLIDE, EXTREME HEAT, WATER

3379
01:59:42,760 --> 01:59:45,920
QUALITY, VECTOR BORN DISEASES,

3380
01:59:45,920 --> 01:59:47,920
WATER AND FOOD, THEY CAUSE

3381
01:59:47,920 --> 01:59:49,120
INCREASE PORBIDDITY AND

3382
01:59:49,120 --> 01:59:50,800
MORTALITY IN WOMEN, INCREASED

3383
01:59:50,800 --> 02:00:01,320
RESPIRATORY AND HEART DISEASE,

3384
02:00:08,920 --> 02:00:10,280
MORE BIRTH COMPLICATIONS SO

3385
02:00:10,280 --> 02:00:13,480
CHRONIC EXPOSURE TO OZONE IN

3386
02:00:13,480 --> 02:00:15,320
PARTICULATE MATTER AND EXPOSURE

3387
02:00:15,320 --> 02:00:17,040
DURING PREGNANCY OR ASSOCIATED

3388
02:00:17,040 --> 02:00:19,200
WITH INCREASED MISTARRAGE AND

3389
02:00:19,200 --> 02:00:19,920
STILL BIRTHS.

3390
02:00:19,920 --> 02:00:21,680
AND THEN PRECONCEPTION STUDY, IT

3391
02:00:21,680 --> 02:00:25,240
WAS FOUND OUT OF EXPOSURE TO AIR

3392
02:00:25,240 --> 02:00:26,480
POLLUTION WITH REDUCED

3393
02:00:26,480 --> 02:00:27,280
ACCOUNTABILITY.

3394
02:00:27,280 --> 02:00:29,000
AND ANOTHER STUDY, WAS CLEAR

3395
02:00:29,000 --> 02:00:31,600
THAT EXPOSURE AIR PLUT ANTS

3396
02:00:31,600 --> 02:00:35,560
DURING PREGNANCY WAS ASSOCIATED

3397
02:00:35,560 --> 02:00:36,040
WITHNYONATAL RESPIRATORY

3398
02:00:36,040 --> 02:00:36,640
COMPLICATIONS.

3399
02:00:36,640 --> 02:00:41,680
NEXT SLIDE, PLEASE. 

3400
02:00:41,680 --> 02:00:43,440
THE DIRECT EFFECT OF INCREASED

3401
02:00:43,440 --> 02:00:44,680
TEMPERATURES THAT INCREASED

3402
02:00:44,680 --> 02:00:46,120
TEMPERATURES CAUSED BY CLIM 8

3403
02:00:46,120 --> 02:00:47,520
CHANGE ALSO IMPACTS WOMEN'S

3404
02:00:47,520 --> 02:00:47,760
HEALTH.

3405
02:00:47,760 --> 02:00:49,400
SO IN THIS STUDY, SMALL CHANGES

3406
02:00:49,400 --> 02:00:51,120
IN TEMPERATURE, DURING THE WEEK

3407
02:00:51,120 --> 02:00:53,240
BEFORE DELIVERY WERE ASSOCIATED

3408
02:00:53,240 --> 02:00:54,560
WITH AN INCREASED CARDIOVASCULAR

3409
02:00:54,560 --> 02:01:04,040
RISK FOR MOTHERS DURING LABOR OR

3410
02:01:04,040 --> 02:01:05,040
DELIVERY.

3411
02:01:05,040 --> 02:01:09,640
SO THIS WAS MORE IN NONHISPANIC

3412
02:01:09,640 --> 02:01:10,920
BLACK WOMEN, THEY WERE SOARNTED

3413
02:01:10,920 --> 02:01:12,120
WITH LOW BIRTH WAY.

3414
02:01:12,120 --> 02:01:18,320
COULD I HAVE THE NEXT SLIDE,

3415
02:01:18,320 --> 02:01:18,560
PLEASE.

3416
02:01:18,560 --> 02:01:23,080
SO THE NEXT STUDY WITH THE

3417
02:01:23,080 --> 02:01:24,360
BIRTHS IT WAS CLEAR ACROSS THE

3418
02:01:24,360 --> 02:01:27,160
UNITED STATES THAT HIGH AMBIENT

3419
02:01:27,160 --> 02:01:29,040
TEMPERATURES, SO IT WAS CLEAR

3420
02:01:29,040 --> 02:01:30,880
THAT HIGH AMBIENT TEMPERATURES

3421
02:01:30,880 --> 02:01:31,800
ACROSS PREGNANCY IS ASSOCIATE

3422
02:01:31,800 --> 02:01:34,160
WIDE THE HIGHER RISK AS WHAT IS

3423
02:01:34,160 --> 02:01:35,800
REFERRED TO TERMED SMALL FOR

3424
02:01:35,800 --> 02:01:37,280
GUESTATIONAL AGE AND LOWER BIRTH

3425
02:01:37,280 --> 02:01:37,560
WAY.

3426
02:01:37,560 --> 02:01:39,080
SO THESE INCREASED RISKS APPEAR

3427
02:01:39,080 --> 02:01:41,600
TO BE MOST PRONOUNCED DURING THE

3428
02:01:41,600 --> 02:01:45,120
SECOND AND THIRD TRIMESTERS OF

3429
02:01:45,120 --> 02:01:50,000
PREGNANCY.

3430
02:01:50,000 --> 02:01:50,480
NEXT SLIDE.

3431
02:01:50,480 --> 02:01:54,440
AND ANOTHER SET OF STUDIES

3432
02:01:54,440 --> 02:01:55,400
DETERMINE AMBIENT CAPACITY AND

3433
02:01:55,400 --> 02:01:55,720
TEMPERATURES.

3434
02:01:55,720 --> 02:01:59,320
SO THEY USE THE TEST TO EVALUATE

3435
02:01:59,320 --> 02:02:02,320
OVARIAN RESERVE CALLED THE AFC.

3436
02:02:02,320 --> 02:02:04,400
SO THEY USE THE PERSPECTIVE

3437
02:02:04,400 --> 02:02:06,840
COHORT DESIGN, STUDY DESIGN WITH

3438
02:02:06,840 --> 02:02:09,200
631 PATIENTS FROM THE MASS

3439
02:02:09,200 --> 02:02:10,200
GENERAL HOSPITAL FERTILITY

3440
02:02:10,200 --> 02:02:11,400
CENTER, THEY STUDIED DAILY

3441
02:02:11,400 --> 02:02:13,600
TEMPERATURE AT THE WOMEN'S

3442
02:02:13,600 --> 02:02:15,320
REDENTIAL ADDRESS FOR 90 DAYS

3443
02:02:15,320 --> 02:02:18,200
BEFORE THEIR AFC MEASUREMENT,

3444
02:02:18,200 --> 02:02:18,800
THEY EVALUATED ASSOCIATIONS

3445
02:02:18,800 --> 02:02:20,320
BETWEEN TEMPERATURE AND AFC AND

3446
02:02:20,320 --> 02:02:22,880
THEY ADJUSTED FOR RELATIVE

3447
02:02:22,880 --> 02:02:25,080
HUMANITY, WITH PARTICULAR MATTER

3448
02:02:25,080 --> 02:02:28,560
EXPOSURE, AGE, EDUCATION,

3449
02:02:28,560 --> 02:02:31,000
SMOKING STATUS, DIAGNOSIS OF

3450
02:02:31,000 --> 02:02:33,480
DIMINISHED OVARIAN RESERVE FOR

3451
02:02:33,480 --> 02:02:35,120
OVULATION DISORDERS SO WHAT THEY

3452
02:02:35,120 --> 02:02:38,200
FOUND IS A 1 DEGREE CENTIGRADE

3453
02:02:38,200 --> 02:02:38,960
INCREASE IN MAXIMUM TEMPERATURE

3454
02:02:38,960 --> 02:02:46,880
WAS SOABT WTD A 1.6% LOWER AFC.

3455
02:02:46,880 --> 02:02:49,800
SO I GUESS THIS SUGGESTS THAT

3456
02:02:49,800 --> 02:02:51,440
HIGHER EXPOSURE TO HIGHER

3457
02:02:51,440 --> 02:02:53,800
TEMPERATURES CAN LEAD TO LOWER

3458
02:02:53,800 --> 02:02:55,760
OVARIAN RESERVE IN HUMANS THAT

3459
02:02:55,760 --> 02:02:58,080
RAISES CONCERN THAT THIS MAY

3460
02:02:58,080 --> 02:02:59,320
RESULT IN ACCELERATED

3461
02:02:59,320 --> 02:03:05,000
REPRODUCTIVE AGING IN WOMEN. 

3462
02:03:05,000 --> 02:03:05,440
NEXT SLIDE, PLEASE.

3463
02:03:05,440 --> 02:03:07,960
SO IN THE CONTEXT OF INDIRECT

3464
02:03:07,960 --> 02:03:08,960
CLIMATE CHANGE, STUDIES HAVE

3465
02:03:08,960 --> 02:03:10,200
SHOWN THAT WOMEN, CHILDREN,

3466
02:03:10,200 --> 02:03:13,240
TEENS AND YOUNG ADULTS ARE MORE

3467
02:03:13,240 --> 02:03:14,960
VULNERABLE TO THE POST-TRAUMATIC

3468
02:03:14,960 --> 02:03:16,560
STRESS AFTER TSUNAMIS AND THAT

3469
02:03:16,560 --> 02:03:18,080
CHILDREN WITH CHRONIC HEALTH

3470
02:03:18,080 --> 02:03:21,240
CONDITIONS AND THOSE THAT MAY

3471
02:03:21,240 --> 02:03:23,640
NEED MENTAL HEALTHCARE

3472
02:03:23,640 --> 02:03:26,520
ULTIMATELY EXPERIENCE HEALTHCARE

3473
02:03:26,520 --> 02:03:28,680
DISRUPTIONS AND IMPACT THEIR

3474
02:03:28,680 --> 02:03:35,840
UNMET CARE AFTER HURRICANES.

3475
02:03:35,840 --> 02:03:37,680
SO IT'S ALSO BEEN FOUND THAT

3476
02:03:37,680 --> 02:03:38,880
THOSE CAUGHT MY CLIMATE CHANGE

3477
02:03:38,880 --> 02:03:43,320
EXPERIENCE MORE LONGER TERM

3478
02:03:43,320 --> 02:03:53,880
PROBLEMS CONTROLLING AGGRESSION 

3479
02:03:54,160 --> 02:03:54,840
NEXT SLIDE, PLEASE. 

3480
02:03:54,840 --> 02:03:57,920
NEXT SLIDE, PLEASE.

3481
02:03:57,920 --> 02:03:59,560
>>I'M GETTING MY SLIDES
MIXED

3482
02:03:59,560 --> 02:04:10,120
UP HERE, LET'S GO ON TO THE NEXT

3483
02:04:14,400 --> 02:04:15,200
SLIDE, PLEASE.

3484
02:04:15,200 --> 02:04:23,800
OKAY SO ANOTHER SET OF STUDIES

3485
02:04:23,800 --> 02:04:25,680
SHOWED THAT WEGINANT WOMEN

3486
02:04:25,680 --> 02:04:28,000
DELIVERED WITHIN 40 WEEKS AFTER

3487
02:04:28,000 --> 02:04:30,600
HURRICANE HARVEY, THEY HAD

3488
02:04:30,600 --> 02:04:34,480
HIGHER MATERNAL MORBIDITY AND

3489
02:04:34,480 --> 02:04:37,240
50% HAYER NEONATAL MORBIDITY.

3490
02:04:37,240 --> 02:04:41,680
WOMEN OF LOW SOCIAL ECONOMIC

3491
02:04:41,680 --> 02:04:42,640
STATUS WERE MOST AFFECTED.

3492
02:04:42,640 --> 02:04:44,680
SO IN THIS CASE, IN ANOTHER SET

3493
02:04:44,680 --> 02:04:46,200
OF STUDIES IT WOULD DETERMINE

3494
02:04:46,200 --> 02:04:48,080
THAT WOMEN WITH BREAST CANCER

3495
02:04:48,080 --> 02:04:50,160
THAT LIVED THROUGH HURRICANE

3496
02:04:50,160 --> 02:04:53,760
KATRINA, HAD A 15% INCREASED

3497
02:04:53,760 --> 02:05:00,120
RISK OF  MORTALITY. 

3498
02:05:00,120 --> 02:05:03,120
SO THE SAME WAS IN COLORECTAL

3499
02:05:03,120 --> 02:05:05,000
CANCER BUT THE IMPACT WAS MOST

3500
02:05:05,000 --> 02:05:07,920
LIKELY CAUSED BY THE DISRUPTION

3501
02:05:07,920 --> 02:05:08,680
IN HEALTHCARE DELIVERY SO AS CAN

3502
02:05:08,680 --> 02:05:11,560
YOU SEE ON THE RIGHT HAND SIDE

3503
02:05:11,560 --> 02:05:15,080
OF THE SLIDE, MISSING EVEN 1

3504
02:05:15,080 --> 02:05:16,800
WEEK OF CHEMO THERAPY HAS

3505
02:05:16,800 --> 02:05:17,960
SIGNIFICANT EFFECTS ON

3506
02:05:17,960 --> 02:05:18,240
MORTALITY.

3507
02:05:18,240 --> 02:05:20,400
NEXT SLID, AND JUST FINALLY,

3508
02:05:20,400 --> 02:05:22,480
IT'S THE--THERE ARE NUMBER OF

3509
02:05:22,480 --> 02:05:24,200
ADDITIONAL INDIRECT IMPACTS OF

3510
02:05:24,200 --> 02:05:25,400
WOMEN'S HEALTH CAUSED BY CLIMATE

3511
02:05:25,400 --> 02:05:26,160
CHANGE AND THEY'RE LIST OFFICE

3512
02:05:26,160 --> 02:05:27,520
OF DIVERSITY THIS SLIDE.

3513
02:05:27,520 --> 02:05:30,320
SO CLIMATE RELATED EVENTS,

3514
02:05:30,320 --> 02:05:30,760
DESTROY HEALTHCARE

3515
02:05:30,760 --> 02:05:31,720
INFRASTRUCTURE, AND THEY CAN

3516
02:05:31,720 --> 02:05:38,880
LEAD TO POWER OUTAGES, STAFF

3517
02:05:38,880 --> 02:05:40,040
SHORTAGES, AND TRANSPORTATION

3518
02:05:40,040 --> 02:05:42,280
DISRUPTIONS AND WE'VE SEEN THIS

3519
02:05:42,280 --> 02:05:44,120
MOST RECENTLY IN FLORIDA AND

3520
02:05:44,120 --> 02:05:45,920
PUERTO RICO, SO CLIMATE RELATED

3521
02:05:45,920 --> 02:05:47,000
EVENTERRINGS CAN OVERWHELM

3522
02:05:47,000 --> 02:05:48,880
HEALTH SYSTEMS, CAN RESULT IN

3523
02:05:48,880 --> 02:05:50,960
LOSS OF MEDICAL RECORDS,

3524
02:05:50,960 --> 02:05:53,600
PROBLEMS ACCESSING OR STORING

3525
02:05:53,600 --> 02:05:54,600
MEDICATIONS CAUSING DISRUPTIONS

3526
02:05:54,600 --> 02:05:57,920
IN MEDICAL SUPPLY CHANGE AND CAN

3527
02:05:57,920 --> 02:05:59,640
DISRUPT RESEARCH INFRASTRUCTURE

3528
02:05:59,640 --> 02:06:00,960
THAT IMPACTS CLINICAL TRIALS.

3529
02:06:00,960 --> 02:06:02,000
SO NEXT SLIDE, PLEASE.

3530
02:06:02,000 --> 02:06:04,400
SO IT'S CLEAR IS THAT CLIMATE

3531
02:06:04,400 --> 02:06:05,600
CHANGE IS IMPACTING HUMAN HEALTH

3532
02:06:05,600 --> 02:06:07,280
IN A NUMBER OF REMARKABLE WAYS

3533
02:06:07,280 --> 02:06:08,160
AND IT'S AFFECTING WOMEN'S

3534
02:06:08,160 --> 02:06:10,360
HEALTH IN A NUMBER OF DIRECT AND

3535
02:06:10,360 --> 02:06:11,440
INDIRECT WAYS SO WHAT ARE WE

3536
02:06:11,440 --> 02:06:13,440
DOING ABOUT ALL OF THIS AT THE

3537
02:06:13,440 --> 02:06:13,800
NIH.

3538
02:06:13,800 --> 02:06:17,880
SO YOU MAY RECALL THAT BACK IN

3539
02:06:17,880 --> 02:06:20,240
2021, PRESIDENT BIDEN ISSUED

3540
02:06:20,240 --> 02:06:21,080
EXECUTIVE ORDER 14008 AND HE

3541
02:06:21,080 --> 02:06:23,720
POINTED TO THE NIH TO TAKE TAKE

3542
02:06:23,720 --> 02:06:25,360
ON THE CHALLENGES OF ADDRESSING

3543
02:06:25,360 --> 02:06:28,200
THE HEALTH EFFECTS ASSOCIATED

3544
02:06:28,200 --> 02:06:28,960
WITH CLIMATE CHANGE.

3545
02:06:28,960 --> 02:06:30,600
SO WE'RE READY FOR THIS

3546
02:06:30,600 --> 02:06:32,200
CHALLENGE BECAUSE STUDYING THE

3547
02:06:32,200 --> 02:06:33,360
HEALTH EFFECTS OF CLIMATE CHANGE

3548
02:06:33,360 --> 02:06:35,400
IS AT A MODEST LEVEL AT LEAST

3549
02:06:35,400 --> 02:06:36,560
WAS WITH US FOR QUITE SOMETIME

3550
02:06:36,560 --> 02:06:39,520
SO THIS IS ESPECIALLY TRUE FOR

3551
02:06:39,520 --> 02:06:41,040
NIEHS, BUT WE RECOGNIZE THAT

3552
02:06:41,040 --> 02:06:43,000
ADDITIONAL MONEY WILL HELP TO

3553
02:06:43,000 --> 02:06:44,200
CATALYZE A MUCH LARGER EFFORT

3554
02:06:44,200 --> 02:06:46,040
THAT AND WE NEEDED ADDITIONAL

3555
02:06:46,040 --> 02:06:47,640
FUNDING TO UNDERTAKE THE

3556
02:06:47,640 --> 02:06:49,280
CHALLENGES ASSOCIATED, THE BIG

3557
02:06:49,280 --> 02:06:50,080
CHALLENGES ASSOCIATED WITH

3558
02:06:50,080 --> 02:06:50,920
CLIMATE CHANGE ASK HEMGHT.

3559
02:06:50,920 --> 02:06:53,080
SO THEREFORE WE WERE ENCOURAGED

3560
02:06:53,080 --> 02:06:56,560
WHEN WE LEARNED THAT CONGRESS

3561
02:06:56,560 --> 02:06:59,080
AND THE PRESIDENT WITH BUDGET

3562
02:06:59,080 --> 02:07:02,080
PROPOSAL RANGING FROM 10 TO

3563
02:07:02,080 --> 02:07:02,680
$100 MILLION CLEARLY RECOGNIZE

3564
02:07:02,680 --> 02:07:03,760
THAT THE HEALTH EFFECTS OF

3565
02:07:03,760 --> 02:07:06,160
CLIMATE CHANGE HAS TO BE A

3566
02:07:06,160 --> 02:07:06,640
PRIORITY FOR FY23.

3567
02:07:06,640 --> 02:07:08,760
SO WE'RE NOT SURE THAT WE WILL

3568
02:07:08,760 --> 02:07:10,600
ACTUALLY GET THE MONEY,

3569
02:07:10,600 --> 02:07:11,280
NEVERTHELESS, WE'VE STARTED

3570
02:07:11,280 --> 02:07:15,240
WORKING TO DEVELOP AN NIH WIDE

3571
02:07:15,240 --> 02:07:16,320
STRATEGY FOR CLIMATE CHANGE AND

3572
02:07:16,320 --> 02:07:18,160
HEALTH, AND WE ARE DOING THIS IN

3573
02:07:18,160 --> 02:07:19,920
A SCALE BECAUSE IT'S CLEAR THIS

3574
02:07:19,920 --> 02:07:22,880
TOPIC MUCH BIGGER THAN WHAT ANY

3575
02:07:22,880 --> 02:07:24,280
SINGLE IC CAN ACCOMPLISH ON ITS

3576
02:07:24,280 --> 02:07:25,680
OWN AND IT'S ALSO THREER THERE

3577
02:07:25,680 --> 02:07:27,120
ARE MANY INSTITUTES AND CENTERSA

3578
02:07:27,120 --> 02:07:28,320
THE NIH THAT HAVE A CLEAN

3579
02:07:28,320 --> 02:07:29,760
INTEREST IN THIS AREA OF

3580
02:07:29,760 --> 02:07:30,720
RESEARCH AND HOPEFULLY I'VE

3581
02:07:30,720 --> 02:07:32,360
CONVINCED YOU THAT THERE ARE

3582
02:07:32,360 --> 02:07:33,240
MANY CHALLENGES, SPECIFICALLY

3583
02:07:33,240 --> 02:07:35,120
THAT RELATE TO WOMEN'S HEALTH.

3584
02:07:35,120 --> 02:07:36,520
SO THEREFORE I'VE TAKEN THE LEAD

3585
02:07:36,520 --> 02:07:41,960
TO REACH OUT TO DOCTORS BIANCHI,

3586
02:07:41,960 --> 02:07:46,080
AT NICHD, DR. GIBBONS,

3587
02:07:46,080 --> 02:07:50,480
DR. GLASS, DR. GORDON, THE MIMH,

3588
02:07:50,480 --> 02:07:53,520
DR. PEREZ-STABLE AT NIMHD AND

3589
02:07:53,520 --> 02:07:55,360
DR. ZENK AT THE NINR AND

3590
02:07:55,360 --> 02:07:57,000
TOGETHER WE ARE FORMING WHAT WE

3591
02:07:57,000 --> 02:07:59,160
CALL THE EXECUTIVE COMMITTEE ON

3592
02:07:59,160 --> 02:08:00,800
CLIMATE CHANGE AND HEALTH.

3593
02:08:00,800 --> 02:08:03,680
SO TOGETHER WE HAVE REENERGIZED

3594
02:08:03,680 --> 02:08:05,480
A WORKING GROUP ACROSS ALL ICs

3595
02:08:05,480 --> 02:08:07,000
OF THE NIH AND THE WORKING GROUP

3596
02:08:07,000 --> 02:08:09,920
AND CO CHAIRED BY AWBRY MILLER

3597
02:08:09,920 --> 02:08:15,160
AT NIEHS AND JOSH ROSEN AT

3598
02:08:15,160 --> 02:08:15,560
FOGARTY.

3599
02:08:15,560 --> 02:08:17,280
SO OUR OWN GWEN IS ON THE ZOOM

3600
02:08:17,280 --> 02:08:18,600
SESSION THIS MORNING IS

3601
02:08:18,600 --> 02:08:19,560
PROVIDING THE COORDINATION TO

3602
02:08:19,560 --> 02:08:22,880
KEEP ALL MOVING FORWARDS WORKING

3603
02:08:22,880 --> 02:08:24,160
IN SYNCHRONY WITH EACH OTHER.

3604
02:08:24,160 --> 02:08:26,960
AND WE HAVE I STEERING GROWM

3605
02:08:26,960 --> 02:08:28,160
WITH DESIGNATED APPOINTEINGS ON

3606
02:08:28,160 --> 02:08:29,880
THE EXECUTIVE COMMITTEE AND THE

3607
02:08:29,880 --> 02:08:31,480
STEERING COMMITTEE, WOOING WITH

3608
02:08:31,480 --> 02:08:32,160
DOCTORS MILLER AND ROSEN THAT

3609
02:08:32,160 --> 02:08:33,560
YOU WILL TO MAKE SURE THE GOALS

3610
02:08:33,560 --> 02:08:34,680
OF THE WORKING GROUP ARE

3611
02:08:34,680 --> 02:08:36,040
ACHIEVED AND THE WORKING GROUP

3612
02:08:36,040 --> 02:08:37,360
AS BEEN VERY BIEWS EXPE WORKING

3613
02:08:37,360 --> 02:08:39,760
ON MANY DIFFERENT PROJECTS AND

3614
02:08:39,760 --> 02:08:41,440
INCLUDING MOST NOTABLY, THE

3615
02:08:41,440 --> 02:08:43,840
DEVELOPMENT OF AN NIH WIDE STRAY

3616
02:08:43,840 --> 02:08:45,280
JECTORY EDGE TOOIC FRAME WOR ARE

3617
02:08:45,280 --> 02:08:46,960
CLIMATE CHANGER AND HEALTH.

3618
02:08:46,960 --> 02:08:48,040
NEXT SLIDE.

3619
02:08:48,040 --> 02:08:50,920
OKAY, SO THE STRATEGIC FRAMEWORK

3620
02:08:50,920 --> 02:08:52,400
AND JUDGE, ANINE, I HAVE AN

3621
02:08:52,400 --> 02:08:52,720
HOUR, RIGHT?

3622
02:08:52,720 --> 02:08:55,400
I WANT TO CHECK, I HAVE ABOUT 20

3623
02:08:55,400 --> 02:08:55,640
MINUTES.

3624
02:08:55,640 --> 02:08:56,960
>>YOU'RE GOOD, YOU'RE
GOOD.

3625
02:08:56,960 --> 02:08:57,640
SOUNDS GOOD.

3626
02:08:57,640 --> 02:08:58,040
OKAY.

3627
02:08:58,040 --> 02:08:59,800
SO I'M WINDING UP HERE.

3628
02:08:59,800 --> 02:09:03,320
SO THE STRATEGIC FRAMEWORK WAS

3629
02:09:03,320 --> 02:09:04,360
DEVELOPED USING SEVERAL SOURCES

3630
02:09:04,360 --> 02:09:05,800
AND IT'S SHOWN ON THIS SLIDE

3631
02:09:05,800 --> 02:09:07,640
HERE, THERE WERE SEVERAL SOURCES

3632
02:09:07,640 --> 02:09:09,760
OF INPUT DATA AND THIS INCLUDED

3633
02:09:09,760 --> 02:09:11,120
A PORTFOLIO ANALYSIS OF THINGS

3634
02:09:11,120 --> 02:09:13,440
THAT WE DO NOT JUST AT NIEHS,

3635
02:09:13,440 --> 02:09:15,960
BUT ACROSS THE NIH, THERE WAS

3636
02:09:15,960 --> 02:09:17,200
ALSO A STRATEGIC WHITE BOARDING

3637
02:09:17,200 --> 02:09:18,160
SESSION WITH MEMBERS OF THE

3638
02:09:18,160 --> 02:09:20,360
WORKING GROUP, THERE WAS A

3639
02:09:20,360 --> 02:09:23,040
LANDSCAPE ANALYSIS AND THERE

3640
02:09:23,040 --> 02:09:24,560
WERE 180 SUBSTANTIVE RESPONSES

3641
02:09:24,560 --> 02:09:25,800
FROM AN RFI THAT THE WORKING

3642
02:09:25,800 --> 02:09:29,440
GROUP ISSUED IN AUGUST OF 20

3643
02:09:29,440 --> 02:09:29,640
TWOON.

3644
02:09:29,640 --> 02:09:30,680
THE FRAMEWORK IS ILLUSTRATED

3645
02:09:30,680 --> 02:09:32,880
WITH WHAT WE CALL THE COG OR THE

3646
02:09:32,880 --> 02:09:33,840
CENTERPIECE OF THE DIAGRAM.

3647
02:09:33,840 --> 02:09:36,240
AS YOU CAN SEE THE FRAMEWORK IS

3648
02:09:36,240 --> 02:09:38,720
BASED ON 4 DIFFERENT CORE

3649
02:09:38,720 --> 02:09:40,400
ELEMENTS WHICH INCLUDE HEALTH

3650
02:09:40,400 --> 02:09:42,000
EFFECTS RESEARCH, HEALTH EQUITY,

3651
02:09:42,000 --> 02:09:45,440
TRAINING AND KASP A R PASTY

3652
02:09:45,440 --> 02:09:46,600
BUILDING AND--CAPACITY BUILDING

3653
02:09:46,600 --> 02:09:48,120
AND INTERVENTION AND SCIENCE AND

3654
02:09:48,120 --> 02:09:50,480
THE CENTER IS FOCUSED ON

3655
02:09:50,480 --> 02:09:51,560
MULTIDISCIPLINARY TRANSFORMATIVE

3656
02:09:51,560 --> 02:09:52,760
RESEARCH AND WHICH REINFORCES

3657
02:09:52,760 --> 02:09:55,400
THOSE COMMENTS BY DR. CRISWELL,

3658
02:09:55,400 --> 02:09:56,040
WHICH MEANS WOO VERMEN INFECTED

3659
02:09:56,040 --> 02:09:57,520
TO WORK TOGETHER IN A REALLY BIG

3660
02:09:57,520 --> 02:09:59,520
WAY TO MAKE THE HEALTH EFFECTS

3661
02:09:59,520 --> 02:10:00,400
OF CLIMATE CHANGE WORK HAPPEN.

3662
02:10:00,400 --> 02:10:03,240
SO THE WORK WILL BE CONDUCTED

3663
02:10:03,240 --> 02:10:05,080
WITH GLOBAL CROSS SECTION

3664
02:10:05,080 --> 02:10:05,920
INTERAGENCY AND COMMUNITY

3665
02:10:05,920 --> 02:10:06,920
PARTNERSHIP EXPTION THE CONS ON

3666
02:10:06,920 --> 02:10:08,200
THE PERIPHERY AND THE

3667
02:10:08,200 --> 02:10:09,480
CIRCUMFERENCE OF THE DIAGRAM,

3668
02:10:09,480 --> 02:10:11,640
ARE REALLY MEANT TO ILLUSTRATE

3669
02:10:11,640 --> 02:10:12,640
THE TYPES OF SCIENCE THAT WE

3670
02:10:12,640 --> 02:10:15,360
NEED TO BE COB DUCTED TO SUPPORT

3671
02:10:15,360 --> 02:10:15,720
THE FRAMEWORK.

3672
02:10:15,720 --> 02:10:17,800
SO AS CAN YOU SEE THE RESEARCH

3673
02:10:17,800 --> 02:10:18,680
AREAS ARE TRULY

3674
02:10:18,680 --> 02:10:20,120
MULTIDISCIPLINARY IN NATURE, AND

3675
02:10:20,120 --> 02:10:21,640
THEY RANGE FROM BASIC

3676
02:10:21,640 --> 02:10:24,240
MECHANISTIC RESEARCH TO

3677
02:10:24,240 --> 02:10:25,440
BEHAVIORIAL SOCIAL SCIENCE

3678
02:10:25,440 --> 02:10:26,640
RESEARCH, EMDEEMIOLOGY AND

3679
02:10:26,640 --> 02:10:28,880
PREDICTIVE MODELING TO

3680
02:10:28,880 --> 02:10:29,320
ADAPTATION RESEARCH.

3681
02:10:29,320 --> 02:10:30,720
I ALSO WANT TO MENTION THAT THE

3682
02:10:30,720 --> 02:10:35,240
SCIENTIFIC DIRECTOR FROM NIEHS,

3683
02:10:35,240 --> 02:10:36,160
DR. DARYL ZELDON IS WORKING WITH

3684
02:10:36,160 --> 02:10:38,560
A GROUP OF DIRECTORS ACROSS THE

3685
02:10:38,560 --> 02:10:40,920
NIH PUT TOGETHER A MODEST SIZE

3686
02:10:40,920 --> 02:10:41,880
CO EMPLOY ELEMENTARY EFFORT

3687
02:10:41,880 --> 02:10:43,000
WITHIN THE RESEARCH PROGRAM AND

3688
02:10:43,000 --> 02:10:44,720
SO IT'S ABOUT ALL OF US NOT ONLY

3689
02:10:44,720 --> 02:10:46,480
THE EXTRAMURAL PROGRAM BUT ALSO

3690
02:10:46,480 --> 02:10:47,360
INTRAMURAL SCIENTISTS AS WELL.

3691
02:10:47,360 --> 02:10:49,920
SO YOU WILL SEE HERE IN THE

3692
02:10:49,920 --> 02:10:51,640
LOWER LEFT HAND CORNER WE

3693
02:10:51,640 --> 02:10:53,040
DEVELOPED A WEBSITE FOR CLIMATE

3694
02:10:53,040 --> 02:10:59,560
CHANGE AND HEALTH, IT'S

3695
02:10:59,560 --> 02:11:02,320
WWW.NIH.GOV/CLIMATEANDHEALTH.

3696
02:11:02,320 --> 02:11:02,600
ONE WORD.

3697
02:11:02,600 --> 02:11:04,120
SO LOOK IF YOU'RE INTERESTED AND

3698
02:11:04,120 --> 02:11:06,560
STAY TUNED WE WILL WORK TO BUILD

3699
02:11:06,560 --> 02:11:07,480
SUFFICIENT SUPPORT PERHAPS THAT

3700
02:11:07,480 --> 02:11:09,440
HUNDRED MILLION DOLLARS IN THE

3701
02:11:09,440 --> 02:11:10,960
PRESIDENT'S BUDGET WILL BE

3702
02:11:10,960 --> 02:11:13,680
ALLOCATED BY CONGRESS IN FY23

3703
02:11:13,680 --> 02:11:15,920
AND AGAIN, IT'S THE OLD STRATEGY

3704
02:11:15,920 --> 02:11:18,520
WELL IT'S IN THE NIEHS BUDGET,

3705
02:11:18,520 --> 02:11:20,640
THE WHOLE STRATEGY TO TO

3706
02:11:20,640 --> 02:11:21,680
DISTRIBUTE THIS ACROSS THE NIERK

3707
02:11:21,680 --> 02:11:23,800
HR. 

3708
02:11:23,800 --> 02:11:26,040
SO NEXT SLIDE, SO I JUST WANT TO

3709
02:11:26,040 --> 02:11:27,360
POINT OUT HERE, IT'S--AND YOU

3710
02:11:27,360 --> 02:11:29,000
WILL HAVE ACCESS TO THESE

3711
02:11:29,000 --> 02:11:30,600
SLIDES, SO USING THE STRATEGIC

3712
02:11:30,600 --> 02:11:31,840
FRAMEWORK WE COME UP WITH

3713
02:11:31,840 --> 02:11:32,680
SEVERAL EXAMPLES OF RESEARCH

3714
02:11:32,680 --> 02:11:35,040
THAT IS NEEDED TO ADDRESS THE

3715
02:11:35,040 --> 02:11:35,920
HEGHT EFFECTS OF CLIMATE CHANGE

3716
02:11:35,920 --> 02:11:38,240
AND I DON'T HAVE TIME NOW TO GO

3717
02:11:38,240 --> 02:11:40,240
OVER ALL OF THESE BUT SUFFICE IT

3718
02:11:40,240 --> 02:11:42,400
TO SAY WE NEED TO STUDY, IESHES

3719
02:11:42,400 --> 02:11:44,600
DENTIFY NEW AND ENERNLGING MELGT

3720
02:11:44,600 --> 02:11:45,880
RISKS FROM CLIMATE CHANGE AND WE

3721
02:11:45,880 --> 02:11:47,040
NEED TO BETTER UNDERSTAND AND

3722
02:11:47,040 --> 02:11:48,200
FOCUS ON THOSE POPULATIONS THAT

3723
02:11:48,200 --> 02:11:49,840
ARE MOST AT RISK AND WHAT'S

3724
02:11:49,840 --> 02:11:51,040
CLEAR AND HOPEFULLY I'VE GIVEN

3725
02:11:51,040 --> 02:11:55,320
YOU PLENTY OF EXAMPLES, WOMEN

3726
02:11:55,320 --> 02:11:56,640
ESPECIALLY DURING PREGNANCY ARE

3727
02:11:56,640 --> 02:11:57,960
AT INCREASED RISK FOR CLIMATE

3728
02:11:57,960 --> 02:11:59,040
CHANGE SO LET ME SKIP OVER ALL

3729
02:11:59,040 --> 02:12:00,720
THE WAY TO THE LAST POINT ON THE

3730
02:12:00,720 --> 02:12:02,600
RIGHT, WE ALSO NEED TO BETTER

3731
02:12:02,600 --> 02:12:03,440
UNDERSTAND HOW COMMUNITIES ARE

3732
02:12:03,440 --> 02:12:05,200
GOING TO ADAPT TO A CHANGE IN

3733
02:12:05,200 --> 02:12:05,480
CLIMATE.

3734
02:12:05,480 --> 02:12:07,360
SO WE BELIEVE THAT THE 27

3735
02:12:07,360 --> 02:12:08,280
EN--STRATEGIESITUTES AND CENTERS

3736
02:12:08,280 --> 02:12:10,400
OF THE NIH ARE UNIQUELY

3737
02:12:10,400 --> 02:12:12,200
POSITIONED TO CONDUCT THE

3738
02:12:12,200 --> 02:12:12,920
NECESSARY RESEARCH, PROVIDE

3739
02:12:12,920 --> 02:12:14,680
EVIDENCE AND THEN TO CONVEY THIS

3740
02:12:14,680 --> 02:12:17,080
KNOWLEDGE TO POLICY MAKERS IN A

3741
02:12:17,080 --> 02:12:20,040
WAY THAT WE CAN ULTIMATELY HELP

3742
02:12:20,040 --> 02:12:21,240
BUILD RESILIENCY AND COMMUNITIES

3743
02:12:21,240 --> 02:12:22,480
ACROSS AMERICA AND ACROSS THE

3744
02:12:22,480 --> 02:12:25,600
DPLOAB. 

3745
02:12:25,600 --> 02:12:26,120
NEXT SLIDE, PLEASE.

3746
02:12:26,120 --> 02:12:29,520
BUT WE'RE NOT WAITING FOR

3747
02:12:29,520 --> 02:12:31,800
CONGRESS TO ALLOCATE NEW

3748
02:12:31,800 --> 02:12:32,440
APPROPRIATIONS IN FY23.

3749
02:12:32,440 --> 02:12:34,120
SO ALL MEMBERS OF THE EXECUTIVE

3750
02:12:34,120 --> 02:12:37,840
COMMITTEE TOGETHER WITH DOCTORS

3751
02:12:37,840 --> 02:12:40,720
TABAK AND SCHWETZ, ALONG WITH

3752
02:12:40,720 --> 02:12:42,360
DOCTORS GOTTESMAN AND SHORE, IN

3753
02:12:42,360 --> 02:12:44,000
THE OFFICE FOR INTERNATIONAL

3754
02:12:44,000 --> 02:12:44,720
CLASSIFICATIONA RAMURAL

3755
02:12:44,720 --> 02:12:46,200
RESEARCH, THEY PROVIDED START UP

3756
02:12:46,200 --> 02:12:49,280
FUNDING FROM THE FY22 OR PART OF

3757
02:12:49,280 --> 02:12:50,680
THEIR FY23 ALLOCATIONS BUT WE'RE

3758
02:12:50,680 --> 02:12:52,920
USING THIS MONEY FOR A NUMBER OF

3759
02:12:52,920 --> 02:12:54,600
INITIATIVES THAT ACROSS THE

3760
02:12:54,600 --> 02:12:55,240
INTRAMURAL AND EXTRAMURAL

3761
02:12:55,240 --> 02:12:57,320
PROGRAMS AT THE NIH.

3762
02:12:57,320 --> 02:12:59,280
THESE INCLUDE BRIEFLY HERE A

3763
02:12:59,280 --> 02:12:59,920
RESEARCH COORDINATING CENTER

3764
02:12:59,920 --> 02:13:02,040
THAT WILL HELP TO MANAGE THE

3765
02:13:02,040 --> 02:13:03,640
DATA BUILD RESEARCH CAPACITY AND

3766
02:13:03,640 --> 02:13:04,560
ADVANCE THE PRIORITIES

3767
02:13:04,560 --> 02:13:07,240
ESTABLISHED BY THE NIH CLIMATE

3768
02:13:07,240 --> 02:13:08,120
CHANGE AND HEALTH STRATEGIC

3769
02:13:08,120 --> 02:13:10,480
FRAMEWORK THAT I SHOW TD YOU A

3770
02:13:10,480 --> 02:13:11,440
COUPLE SLIDES AGO.

3771
02:13:11,440 --> 02:13:12,400
SO ADDITIONALLY WE FOUND START

3772
02:13:12,400 --> 02:13:13,760
UP FUNDING TO SUPPORT THE

3773
02:13:13,760 --> 02:13:15,240
ALLIANCE FOR COMMUNITY

3774
02:13:15,240 --> 02:13:16,160
ENGAGEMENT FOCUSED ON CLIMATE

3775
02:13:16,160 --> 02:13:16,960
CHANGE AND HEALTH.

3776
02:13:16,960 --> 02:13:19,280
WE'RE CALLING THIS THE ACCH.

3777
02:13:19,280 --> 02:13:21,000
SO THIS ALLIANCE WILL ALLOW THE

3778
02:13:21,000 --> 02:13:22,840
NIH TO ENGIJ COMMUNITIES THAT

3779
02:13:22,840 --> 02:13:24,920
ARE MOST IMPACTED BY CLIMATE

3780
02:13:24,920 --> 02:13:25,240
CHANGE.

3781
02:13:25,240 --> 02:13:26,840
THESE OF COURSE WOULD BE

3782
02:13:26,840 --> 02:13:28,840
UNDERSERVED AND RACIAL AND

3783
02:13:28,840 --> 02:13:30,360
ETHNIC MINORITY AND RURAL

3784
02:13:30,360 --> 02:13:32,160
POPULATIONS SO THE ACCH BUILDS

3785
02:13:32,160 --> 02:13:34,480
OFF A SUCCESSFUL PROGRAM THAT

3786
02:13:34,480 --> 02:13:37,600
WAS ESTABLISHED AT NHLBI AND

3787
02:13:37,600 --> 02:13:39,120
NIMHD TO DESCREASES THE HEALTH

3788
02:13:39,120 --> 02:13:40,400
DISPARITIES RESEARCH ASSOCIATE

3789
02:13:40,400 --> 02:13:41,400
WIDE COVID-19 TESTING.

3790
02:13:41,400 --> 02:13:43,360
SO THE ACCH WILL WORK IN CLOSE

3791
02:13:43,360 --> 02:13:44,680
COLLABORATION WITH COMMUNITY

3792
02:13:44,680 --> 02:13:47,840
PARTNER PRS PROMOTE ENCLIEWGZ,

3793
02:13:47,840 --> 02:13:50,040
IN THE CCH RESEARCH FRAMEWORK OF

3794
02:13:50,040 --> 02:13:51,440
THE UNDERSERVED AND RACIAL

3795
02:13:51,440 --> 02:13:53,120
ETHNIC MINORITY AND RURAL

3796
02:13:53,120 --> 02:13:55,520
POPULATIONS AND WE WILL DEVELOP

3797
02:13:55,520 --> 02:13:57,720
EFFECTIVE MESSAGING TO WORK TO

3798
02:13:57,720 --> 02:13:58,280
COUNTER MISINFORMATION.

3799
02:13:58,280 --> 02:14:00,480
AGAIN, BA BEING TO SOME OF THOSE

3800
02:14:00,480 --> 02:14:02,920
POINTS WE RAISED WITH

3801
02:14:02,920 --> 02:14:04,280
DR. CRISWELL, WE HAVE TO LEARN

3802
02:14:04,280 --> 02:14:07,160
TO COMMUNICATE IN WAY WE CAN

3803
02:14:07,160 --> 02:14:07,960
COUNTER MISINFORMATION AND IN

3804
02:14:07,960 --> 02:14:09,760
THE END WE HOPE THAT THE ACCH

3805
02:14:09,760 --> 02:14:11,160
WILL BUILD TRUST IN THOSE

3806
02:14:11,160 --> 02:14:12,720
UNDERSERVED AND RURAL

3807
02:14:12,720 --> 02:14:13,000
COMMUNITIES.

3808
02:14:13,000 --> 02:14:14,120
SO ADDITIONALLY MEMBERS OF THE

3809
02:14:14,120 --> 02:14:15,360
CCH WORKING GROUP HAD BEEN

3810
02:14:15,360 --> 02:14:17,120
ENGAGING WITH THE ICs TO GET

3811
02:14:17,120 --> 02:14:18,480
THE WORD OUT THAT THERE'S

3812
02:14:18,480 --> 02:14:20,560
INTEREST IN SUPPORTING

3813
02:14:20,560 --> 02:14:21,000
INVESTIGATOR INITIATED

3814
02:14:21,000 --> 02:14:21,280
PROPOSALS.

3815
02:14:21,280 --> 02:14:22,520
FOCUSED ON THE HEALTH EFFECTS OF

3816
02:14:22,520 --> 02:14:23,960
CLIMB 8 CHANGE AND AS FAR AS

3817
02:14:23,960 --> 02:14:27,440
THIS, THERE WILL BE NOSIs THAT

3818
02:14:27,440 --> 02:14:29,440
ARTICULATE THE RELEVANCE FOR

3819
02:14:29,440 --> 02:14:30,480
ADOPTING PRACTICAL TECHNOLOGIES

3820
02:14:30,480 --> 02:14:31,800
FOR CAPTURING THE HEALTH EFFECTS

3821
02:14:31,800 --> 02:14:35,160
OF CLIMATE CHANGE IN SBIR

3822
02:14:35,160 --> 02:14:44,600
APPLICATIONS. 

3823
02:14:44,600 --> 02:14:45,520
NEXT SLIDE, PLEASE.

3824
02:14:45,520 --> 02:14:47,480
AND INCLUDED IN OUR NEW PROGRAM,

3825
02:14:47,480 --> 02:14:50,080
IT IS THE NIH CLIMATE AND HEALTH

3826
02:14:50,080 --> 02:14:52,000
SCHOLARS PROGRAM, SO THIS WILL

3827
02:14:52,000 --> 02:14:53,520
BRING THOSE WORKING IN CLIMATE

3828
02:14:53,520 --> 02:14:54,800
CHANGE AND HEALTH ON CAMPUS AND

3829
02:14:54,800 --> 02:14:56,840
TO WORK WITH STAFF AT THE NIH

3830
02:14:56,840 --> 02:14:59,400
AND THOSE INVOLVED IN THE NIH

3831
02:14:59,400 --> 02:15:00,200
ACCH INITIATIVE.

3832
02:15:00,200 --> 02:15:02,840
THESE SCHOLARS WILL BE INVITED

3833
02:15:02,840 --> 02:15:04,640
TO COLLABORATE WITH NIH STAFF ON

3834
02:15:04,640 --> 02:15:06,320
1 OR MORE ACTIVITIES RELATED TO

3835
02:15:06,320 --> 02:15:07,480
RESEARCH, TRAINING AND POLICY,

3836
02:15:07,480 --> 02:15:09,880
AND IT WILL BE IN A UNIQUE

3837
02:15:09,880 --> 02:15:12,000
OPPORTUNITY FOR SCIENTISTS FROM

3838
02:15:12,000 --> 02:15:13,240
OUTSIDE OF U.S. FEDERAL

3839
02:15:13,240 --> 02:15:14,600
GOVERNMENT TO SHARE KNOWLEDGE,

3840
02:15:14,600 --> 02:15:15,680
INTEREST AND PASSION AROUND

3841
02:15:15,680 --> 02:15:17,080
CLIMATE CHANGE AND HEALTH AND TO

3842
02:15:17,080 --> 02:15:20,000
DO THIS WITH NIH LABORATORIES,

3843
02:15:20,000 --> 02:15:20,640
PROGRAM OFFICERS, OTHERS ACROSS

3844
02:15:20,640 --> 02:15:21,520
THE NIESH H.

3845
02:15:21,520 --> 02:15:26,520
SO DID TAILS ON THE PROGRAM ARE

3846
02:15:26,520 --> 02:15:31,200
AT NIH.GOV/CLIMAT EAND AND

3847
02:15:31,200 --> 02:15:31,400
HEALTH.

3848
02:15:31,400 --> 02:15:35,480
SO IN THE INTEREST OF TIME,

3849
02:15:35,480 --> 02:15:37,520
THERE'S A LOT OF INTEREST IN

3850
02:15:37,520 --> 02:15:38,760
STUDYING HEGHTS OF CLIMATE

3851
02:15:38,760 --> 02:15:39,920
CHANGE WITHIN OUR INTRA MIEWR

3852
02:15:39,920 --> 02:15:40,480
WILLA RESEARCH PROGRAM.

3853
02:15:40,480 --> 02:15:43,040
SO YOUR SCIENTIFIC DIRECTORS ARE

3854
02:15:43,040 --> 02:15:44,880
WORKING TOGETHER WITH DR. ZELDAN

3855
02:15:44,880 --> 02:15:47,280
TO PUT TOGETHER A NUMBER OF

3856
02:15:47,280 --> 02:15:49,520
INITIATIVES SO IT WILL BE A

3857
02:15:49,520 --> 02:15:50,600
MODEL EFFORT INVOLVING OUR

3858
02:15:50,600 --> 02:15:51,560
INTRAMURAL PROGRAMS AND THAT

3859
02:15:51,560 --> 02:15:52,520
WILL BE COMPLEMENTING THE

3860
02:15:52,520 --> 02:15:53,920
EFFORTS IN OUR EXTRAMURAL

3861
02:15:53,920 --> 02:15:56,720
PROGRAMS. 

3862
02:15:56,720 --> 02:15:57,240
SO NEXT SLIDE.

3863
02:15:57,240 --> 02:15:59,680
SO JUST TO SUMMARIZE IT ALL,

3864
02:15:59,680 --> 02:16:01,320
AGAIN, VISIT THE CLIMATE AND

3865
02:16:01,320 --> 02:16:06,800
HEALTH WEBSITE, IF YOU WANT MORE

3866
02:16:06,800 --> 02:16:09,600
INFORMATION AND WE'LL BE HOSTING

3867
02:16:09,600 --> 02:16:11,040
ANY FUNDING OPPORTUNITIES IF

3868
02:16:11,040 --> 02:16:13,520
THEY EXIST AND WE GET THOSE

3869
02:16:13,520 --> 02:16:14,720
ADDITIONAL DOLLARS COMING FROM

3870
02:16:14,720 --> 02:16:16,240
CONGRESS IF FY23, AND WE ALSO

3871
02:16:16,240 --> 02:16:17,200
WANT TO POINT OUT THAT WE

3872
02:16:17,200 --> 02:16:18,600
CONTINUE TO SUPPORT A PUBLIC

3873
02:16:18,600 --> 02:16:20,120
SEMINAR SERIES AND DON'T FORGET

3874
02:16:20,120 --> 02:16:21,880
ABOUT THE CLIMATE CHANGE IN

3875
02:16:21,880 --> 02:16:23,000
HEALTH LITERATURE PORTAL, SO THE

3876
02:16:23,000 --> 02:16:24,840
PORTAL IS A SEARCHABLE DATABASE

3877
02:16:24,840 --> 02:16:27,520
WITH EASY ACCESS TO THE MOST

3878
02:16:27,520 --> 02:16:28,360
RELEVANT SCIENTIFIC LITERATURE

3879
02:16:28,360 --> 02:16:29,960
THAT RELATE TO HEALTH IMPACTS OF

3880
02:16:29,960 --> 02:16:30,520
CLIMATE CHANGE.

3881
02:16:30,520 --> 02:16:33,240
SOPHISTICATEDY LET ME STOP AT

3882
02:16:33,240 --> 02:16:35,440
THIS POINT AND I THINK I'VE

3883
02:16:35,440 --> 02:16:38,440
GIVEN TIME FOR ANY QUESTIONS

3884
02:16:38,440 --> 02:16:43,560
THAT YOU MAY HAVE OR MEMBERS OF

3885
02:16:43,560 --> 02:16:44,640
YOUR ADVISORY GROUP MAY HAVE

3886
02:16:44,640 --> 02:16:45,960
RELATIVE TO WORK ON CLIMATE

3887
02:16:45,960 --> 02:16:48,200
CHANGE IN WOMEN'S HEALTH OR WORK

3888
02:16:48,200 --> 02:16:49,360
AT NIEHS, SO THANK YOU.

3889
02:16:49,360 --> 02:16:51,560
>>THANK YOU SO MUCH RICK
FOR

3890
02:16:51,560 --> 02:16:52,160
THAT WHIRL WIND.

3891
02:16:52,160 --> 02:16:55,080
YOU COVERED SO MANY AREAS OF THE

3892
02:16:55,080 --> 02:16:58,520
WORK THAT NIEHS LEADS AND THAT

3893
02:16:58,520 --> 02:16:59,920
YOU LEAD AND ENDING WITH THE

3894
02:16:59,920 --> 02:17:01,320
CLIMATE CHANGE WHICH IS THE

3895
02:17:01,320 --> 02:17:02,400
TOPIC I REALLY WANTED TO HEAR

3896
02:17:02,400 --> 02:17:05,320
FROM YOU AND PRESENTED SOME VERY

3897
02:17:05,320 --> 02:17:06,840
COMPELLING DATA AROUND WHAT WE

3898
02:17:06,840 --> 02:17:09,480
ALREADY KNOW AND SO, THERE IS 1

3899
02:17:09,480 --> 02:17:11,240
QUESTION ALREADY FROM AN

3900
02:17:11,240 --> 02:17:13,080
ADVISORY COMMITTEE MEMBER IN THE

3901
02:17:13,080 --> 02:17:14,600
CHAT, DR. HIGGINS DO YOU WANT TO

3902
02:17:14,600 --> 02:17:16,640
UNMUTE AND TURN YOUR VIDEO - ON

3903
02:17:16,640 --> 02:17:18,960
AND I WOULD INVITE ANY OF THE

3904
02:17:18,960 --> 02:17:20,360
MEMBERS WHO WOULD LIKE TO ASK A

3905
02:17:20,360 --> 02:17:21,560
QUESTION, FEEL FREE TO TURN YOUR

3906
02:17:21,560 --> 02:17:25,960
VIDEO ON AS WELL.

3907
02:17:25,960 --> 02:17:26,280
DR. HIGGINS?

3908
02:17:26,280 --> 02:17:28,200
>>YEAH, THANKS, THANKS
FOR THE

3909
02:17:28,200 --> 02:17:29,120
REALLY STIMULATING PRESENTATION,

3910
02:17:29,120 --> 02:17:29,920
I ENJOYED IT.

3911
02:17:29,920 --> 02:17:33,000
AND I WAS WONDERING IF YOU COULD

3912
02:17:33,000 --> 02:17:34,040
COMMENT ON AND ONGOING RESEARCH

3913
02:17:34,040 --> 02:17:37,280
OR ANY KNOWLEDGE YOU MIGHT HAVE

3914
02:17:37,280 --> 02:17:38,800
REGUARDING MATERNAL SMOKING AS A

3915
02:17:38,800 --> 02:17:42,240
RISK FACTOR FOR THE ADVERSE

3916
02:17:42,240 --> 02:17:45,360
EFFECTS OF EBS POSURES,

3917
02:17:45,360 --> 02:17:47,000
POLLUTANT EXPOSURES BUT ALSO

3918
02:17:47,000 --> 02:17:48,880
CLIMATE CHANGE ON PREGNANCY

3919
02:17:48,880 --> 02:17:49,320
OUTCOMES?

3920
02:17:49,320 --> 02:17:53,440
>>YEAH, WELL, LET ME--IN
FACT I

3921
02:17:53,440 --> 02:17:55,160
WILL ASK DOCTOR COLEMAN, WHERE

3922
02:17:55,160 --> 02:17:57,400
IS SHE HERE, GWEN IF YOU COULD

3923
02:17:57,400 --> 02:17:59,280
JUST TURN ON YOUR CAMERA HERE I

3924
02:17:59,280 --> 02:18:00,240
WILL JUST COMMENT THAT SMOKING

3925
02:18:00,240 --> 02:18:05,040
OF COURSE IS ASSOCIATED WITH

3926
02:18:05,040 --> 02:18:06,440
THAT PARTICULATE MATTER THAT IS

3927
02:18:06,440 --> 02:18:07,720
ALSO A COMPONENT OF AIR

3928
02:18:07,720 --> 02:18:08,680
POLLUTION.

3929
02:18:08,680 --> 02:18:09,960
SO I'M NOT--GWEN ARE YOU

3930
02:18:09,960 --> 02:18:16,000
FAMILIAR WITH ANY SPECIFIC

3931
02:18:16,000 --> 02:18:16,200
STUDIES?

3932
02:18:16,200 --> 02:18:19,400
AND YOU MAY BE INVOLVED WITH

3933
02:18:19,400 --> 02:18:20,680
STUDIES INVOLVING SMOKING AS A

3934
02:18:20,680 --> 02:18:22,680
RISK FACTOR AND CLIMATE CHANGE

3935
02:18:22,680 --> 02:18:23,440
AND PREGMANCY OUTCOMES.

3936
02:18:23,440 --> 02:18:24,040
SO GO AHEAD.

3937
02:18:24,040 --> 02:18:25,240
>>SO THANKS FOR GIVING ME
THE

3938
02:18:25,240 --> 02:18:26,040
OPPORTUNITY.

3939
02:18:26,040 --> 02:18:27,720
SO IN OUR INTRAMURAL PROGRAM,

3940
02:18:27,720 --> 02:18:29,520
DR. HIGGINS WE HAVE A CONSORTIUM

3941
02:18:29,520 --> 02:18:32,040
CALLED THE PACE CONSORTIUM

3942
02:18:32,040 --> 02:18:33,680
THAT'S RUNED BY DR. STEPHANIE

3943
02:18:33,680 --> 02:18:34,880
LONDON WHO BROUGHT TOGETHER

3944
02:18:34,880 --> 02:18:37,120
STUDIES FROM ALL AROUND THE

3945
02:18:37,120 --> 02:18:39,120
WORLD AND WERE ABLE TO USE

3946
02:18:39,120 --> 02:18:40,400
BIOLOGICAL SAMPLES THAT WERE

3947
02:18:40,400 --> 02:18:41,520
COLLECTED IN THESE BIRTH

3948
02:18:41,520 --> 02:18:45,400
COHORTS, AND THEY LOOKED AT

3949
02:18:45,400 --> 02:18:47,200
MATERNAL SMOKING AND EPIGENETIC

3950
02:18:47,200 --> 02:18:50,120
MARKS IN THOSE SPECIMENS.

3951
02:18:50,120 --> 02:18:52,640
AND BACK IN 2013 WERE ABLE TO

3952
02:18:52,640 --> 02:18:56,000
PUBLISH AN ANALYSIS SHOWING THAT

3953
02:18:56,000 --> 02:18:58,040
THERE WERE DIRECT CHANGES DM

3954
02:18:58,040 --> 02:18:59,200
METHYLATION ASSOCIATE WIDE

3955
02:18:59,200 --> 02:18:59,600
MATERNAL SMOKING.

3956
02:18:59,600 --> 02:19:00,840
BUT I DO LIKE THE WAY YOU PUT

3957
02:19:00,840 --> 02:19:02,920
YOUR QUESTION IN THE CONTEXT OF

3958
02:19:02,920 --> 02:19:06,000
THE MULTIPLE EXPOSURES THAT

3959
02:19:06,000 --> 02:19:07,960
WOMEN ARE ASSOCIATED WITH DURING

3960
02:19:07,960 --> 02:19:09,160
THEIR PREGNANCY AND RICK DID

3961
02:19:09,160 --> 02:19:12,360
TALK EARLIER ABOUT THE EXPOSE

3962
02:19:12,360 --> 02:19:15,320
OME CONCEPT SO I'M NOT SURE OF A

3963
02:19:15,320 --> 02:19:16,240
MORE CURRENT PUBLICATIONS THAT

3964
02:19:16,240 --> 02:19:18,120
MIGHT SHOW THE INTERACTIONS BUT

3965
02:19:18,120 --> 02:19:20,160
1 WOULD IMAGINE THE BIOLOGICAL

3966
02:19:20,160 --> 02:19:21,760
TARGETS FOR A VARIETIES OF THESE

3967
02:19:21,760 --> 02:19:23,840
EXPOSURES WERE IN THE SAME

3968
02:19:23,840 --> 02:19:24,760
PATHWAYS, YOU MIGHT SAN

3969
02:19:24,760 --> 02:19:30,840
FRANCISCO SEE SOME SYNERGISTIC

3970
02:19:30,840 --> 02:19:31,120
RESPONSES.

3971
02:19:31,120 --> 02:19:31,800
>>I APPRECIATE THAT

3972
02:19:31,800 --> 02:19:32,080
INFORMATION.

3973
02:19:32,080 --> 02:19:33,320
I HADN'T THOUGHT ABOUT IT

3974
02:19:33,320 --> 02:19:35,640
PREVIOUSLY BUT I HAVE AN ONGOING

3975
02:19:35,640 --> 02:19:37,840
CONCERN THAT WE UNDERTREAT

3976
02:19:37,840 --> 02:19:40,160
SMOKING DURING PREGNANCY AND

3977
02:19:40,160 --> 02:19:41,680
THIS KIND OF INFORMATION WHICH

3978
02:19:41,680 --> 02:19:45,240
AGAIN, I HADN'T REALLY THOUGHT

3979
02:19:45,240 --> 02:19:46,880
ABOUT BEFORE, BUT I THINK IT'S

3980
02:19:46,880 --> 02:19:48,240
LIKELY THAT THERE WOULD BE

3981
02:19:48,240 --> 02:19:51,920
INTERACTIONS AND THE MORE WE CAN

3982
02:19:51,920 --> 02:19:53,440
SHOW THE HARMING, ASSOCIATED

3983
02:19:53,440 --> 02:19:54,520
WITH MATERNAL SMOKING, THE MORE

3984
02:19:54,520 --> 02:19:56,920
I THINK WE COULD GET THE SUPPORT

3985
02:19:56,920 --> 02:19:59,760
WE NEED TO BETTER TREAT THE

3986
02:19:59,760 --> 02:20:00,000
PROBLEM.

3987
02:20:00,000 --> 02:20:02,640
SO THANK YOU VERY MUCH.

3988
02:20:02,640 --> 02:20:03,920
>>SORRY, I GUESS I

3989
02:20:03,920 --> 02:20:04,880
MISUNDERSTOOD YOUR QUESTION, I

3990
02:20:04,880 --> 02:20:06,080
THOUGHT THIS WAS DIRECTLY

3991
02:20:06,080 --> 02:20:08,520
RELATED TO THE CLIMATE CHANGE IN

3992
02:20:08,520 --> 02:20:10,320
PREGNANCY OUTCOMES, BUT GWEN'S

3993
02:20:10,320 --> 02:20:12,280
RIGHT, WE HAVE--IF YOUR VERY

3994
02:20:12,280 --> 02:20:14,200
INTERESTED IT'S A WONDERFUL

3995
02:20:14,200 --> 02:20:15,840
EPIDEMIOLOGICAL STUDY AND THERE

3996
02:20:15,840 --> 02:20:18,400
ARE SPECIFIC METHYLATION SITES

3997
02:20:18,400 --> 02:20:20,880
ON THE GENOMES THAT ARE

3998
02:20:20,880 --> 02:20:24,160
INFLUENCED BY SMOKING DURING

3999
02:20:24,160 --> 02:20:25,440
PREGNANCY.

4000
02:20:25,440 --> 02:20:27,240
>>YEAH, NO, I WAS HOPING
THAT

4001
02:20:27,240 --> 02:20:29,080
THERE MIGHT BE SOME INFORMATION

4002
02:20:29,080 --> 02:20:32,440
ON THE CLIMATE CHANGE IMPACTS AS

4003
02:20:32,440 --> 02:20:35,440
WELL, THE MORE AS I WAS JUST

4004
02:20:35,440 --> 02:20:37,520
SUGGESTING, THE MORE WE KNOW

4005
02:20:37,520 --> 02:20:39,400
ABOUT SMOKING DURING PREGNANCY

4006
02:20:39,400 --> 02:20:41,240
AS A COMPLICATING FACTOR, AND I

4007
02:20:41,240 --> 02:20:42,680
NEVER THOUGHT ABOUT CLIMATE

4008
02:20:42,680 --> 02:20:44,520
CHANGE BEFORE THIS PRESENTATION,

4009
02:20:44,520 --> 02:20:46,920
BUT IT VERY WELL MAY BE 1, THE

4010
02:20:46,920 --> 02:20:49,720
MORE I THINK WE COULD GET

4011
02:20:49,720 --> 02:20:51,680
IMPROVE THE SUPPORT TO DO BETTER

4012
02:20:51,680 --> 02:20:55,080
WITH SMOKING CESSATION DURING

4013
02:20:55,080 --> 02:20:55,320
PREGNANCY.

4014
02:20:55,320 --> 02:20:58,560
SO THANK YOU VERY MUCH.

4015
02:20:58,560 --> 02:21:00,240
>>WELL SMOKING 2.5 SO I
AM GLAD

4016
02:21:00,240 --> 02:21:02,120
THIS WAS HELPFUL FOR YOU.

4017
02:21:02,120 --> 02:21:02,480
TERRIFIC.

4018
02:21:02,480 --> 02:21:04,240
THANK YOU OKAY, LET'S SEE I

4019
02:21:04,240 --> 02:21:06,120
THINK WE HAVE--IS THERE ANOTHER

4020
02:21:06,120 --> 02:21:06,400
QUESTION.

4021
02:21:06,400 --> 02:21:09,360
>>YES DR. KLEIN HAS A
QUESTION.

4022
02:21:09,360 --> 02:21:11,640
>>THANK YOU SO MUCH IF
ARE THIS

4023
02:21:11,640 --> 02:21:13,160
FAP TAFTIC DISCUSSION, MUCH OF

4024
02:21:13,160 --> 02:21:14,880
WHAT YOU TALKED ABOUT WITH

4025
02:21:14,880 --> 02:21:18,880
REGARD TO HOW CLIMATE CHANGE

4026
02:21:18,880 --> 02:21:20,880
MIGHT BE AFFECTING PREGNANT

4027
02:21:20,880 --> 02:21:23,120
WOMEN TO ALTER OFFSPRING

4028
02:21:23,120 --> 02:21:26,640
OUTCOMES REALLY RESONATED WITH

4029
02:21:26,640 --> 02:21:26,880
ME.

4030
02:21:26,880 --> 02:21:28,520
I WORK WITH INFECTIOUS DISEASES

4031
02:21:28,520 --> 02:21:30,960
AND WE DO WORK IN HUMANS BUT WE

4032
02:21:30,960 --> 02:21:33,560
ALSO THEN TRY TO TURN TO SOME OF

4033
02:21:33,560 --> 02:21:39,200
OUR ANIMAL MODELS TO TRY TO MORE

4034
02:21:39,200 --> 02:21:43,800
MECHANISTICALLY INVESTIGATE HOW

4035
02:21:43,800 --> 02:21:45,520
INFECTION DURING PREGNANCY

4036
02:21:45,520 --> 02:21:46,440
ALTERS OFFSPRING OUTCOMES AND

4037
02:21:46,440 --> 02:21:49,680
WHETHER IT'S BEEN ZEKEA,

4038
02:21:49,680 --> 02:21:50,960
INFLUENZA, MORE RECENTLY WORK

4039
02:21:50,960 --> 02:21:54,640
WE'RE DOING WITH SARS-COV-2 A

4040
02:21:54,640 --> 02:21:58,400
LOT OF WHAT YOU DESCRIBE CAN

4041
02:21:58,400 --> 02:22:00,480
SMALL GUESTATIONAL AGE, WE

4042
02:22:00,480 --> 02:22:01,520
OBSERVE NEURAL BEHAVIORIAL

4043
02:22:01,520 --> 02:22:03,720
DEFICITS IN OUR ANIMAL MODELS,

4044
02:22:03,720 --> 02:22:05,760
WE'RE EVEN SEEING DEFICITS IN

4045
02:22:05,760 --> 02:22:06,960
IMMUNITY TO CHILDHOOD VACCINES

4046
02:22:06,960 --> 02:22:11,280
IN OUR ANIMAL MODELS WHEN

4047
02:22:11,280 --> 02:22:13,120
OFFSPRING HAVE BEEN EXPOSED TO

4048
02:22:13,120 --> 02:22:13,520
THESE INFECTIONS.

4049
02:22:13,520 --> 02:22:15,040
SO I GUESS I'M JUST LOOKING FOR,

4050
02:22:15,040 --> 02:22:17,280
YOU KNOW A COMMENT OR SOME KIND

4051
02:22:17,280 --> 02:22:18,280
OF INSIGHT.

4052
02:22:18,280 --> 02:22:20,680
I STARTED TO WONDER, YOU KNOW

4053
02:22:20,680 --> 02:22:23,960
DOES CLIMATE CHANGE ADD THIS 1-2

4054
02:22:23,960 --> 02:22:24,160
PUNCH?

4055
02:22:24,160 --> 02:22:26,200
DO WE START TO SEE THAT THIS

4056
02:22:26,200 --> 02:22:27,480
IMPACT OF INFECTION AND WE'VE

4057
02:22:27,480 --> 02:22:29,240
KNOWN THIS AND THIS WAS

4058
02:22:29,240 --> 02:22:31,320
DOCUMENTED EVENT DURING THE 1918

4059
02:22:31,320 --> 02:22:35,320
FLU PANDEMIC HAS SOME OF THESE

4060
02:22:35,320 --> 02:22:35,960
ADVERSE PREGNANCY OUTCOMES, BUT

4061
02:22:35,960 --> 02:22:38,960
WHEN YOU START TO SEE MORE OF

4062
02:22:38,960 --> 02:22:41,840
THIS AS A RESULT OF CLIMATE

4063
02:22:41,840 --> 02:22:44,360
CHANGE, FURTHER ADDING TO THIS

4064
02:22:44,360 --> 02:22:45,960
COMPLICATION OF INFECTION AND OF

4065
02:22:45,960 --> 02:22:47,240
COURSE I'M THINKING ABOUT IT

4066
02:22:47,240 --> 02:22:49,840
BECAUSE WE'VE JUST COME OUT OF A

4067
02:22:49,840 --> 02:22:50,440
PANDEMIC.

4068
02:22:50,440 --> 02:22:53,480
>>WELL THATIA A
MULTIFACETED

4069
02:22:53,480 --> 02:22:53,760
QUESTION.

4070
02:22:53,760 --> 02:22:55,560
SO OF COURSE WITH CLOIMATE

4071
02:22:55,560 --> 02:22:57,840
CHANGE YOU'RE GOING TO BE SEEING

4072
02:22:57,840 --> 02:23:01,480
INCREASED INCIDENCE OF CERTAIN

4073
02:23:01,480 --> 02:23:04,320
INFECTIONS FROM VIRUSES AND

4074
02:23:04,320 --> 02:23:06,160
BACTERIA, INFECTIONS OF THINGS

4075
02:23:06,160 --> 02:23:08,280
THAT MAY NOT BE ASSOCIATED WITH

4076
02:23:08,280 --> 02:23:11,520
CERTAIN PARTS OF THE COUNTRY BUT

4077
02:23:11,520 --> 02:23:12,240
AIDATIONALLY, WITH CLIMATE

4078
02:23:12,240 --> 02:23:15,240
CHANGE, YOU HAVE VARIATIONS AND

4079
02:23:15,240 --> 02:23:16,840
ENVIRONMENTAL EXPOSURES, THERE

4080
02:23:16,840 --> 02:23:18,160
MAY BE DISTRIBUTIONS OF

4081
02:23:18,160 --> 02:23:23,960
ENVIRONMENTAL EXPOSURES AND FOR

4082
02:23:23,960 --> 02:23:26,240
EXAMPLE, SOME OF OUR

4083
02:23:26,240 --> 02:23:28,160
INVESTIGATORS HAVE DETERMINED

4084
02:23:28,160 --> 02:23:30,680
THAT PFAS, AND PFAS DESCROWKS IS

4085
02:23:30,680 --> 02:23:32,880
A RESULT OF A WEATHER RELATED

4086
02:23:32,880 --> 02:23:38,960
COMMENT EVENT CAN SUPPRESS THE

4087
02:23:38,960 --> 02:23:39,520
IMMUNE SYSTEM.

4088
02:23:39,520 --> 02:23:44,120
AND SO THEY COULD COMPROMISE THE

4089
02:23:44,120 --> 02:23:45,520
ABILITY TO AMOUNT A POSITIVE

4090
02:23:45,520 --> 02:23:47,280
RESPONSE TO A VACCINATION EVENT.

4091
02:23:47,280 --> 02:23:48,600
SO THERE ARE JUST LOTS OF THINGS

4092
02:23:48,600 --> 02:23:50,160
GOING ON, DO YOU HAVE GENE

4093
02:23:50,160 --> 02:23:55,200
ENVIRONMENT EEIVELGTS YOU HAVE

4094
02:23:55,200 --> 02:23:57,240
INCREASED TRANSMISSION OF

4095
02:23:57,240 --> 02:23:58,120
INFECTIOUS AGENTS AND THIS

4096
02:23:58,120 --> 02:23:59,200
INTERACTION WITH THE

4097
02:23:59,200 --> 02:24:00,600
ENVIRONMENTAL EXPOSURES THAT

4098
02:24:00,600 --> 02:24:04,440
WOULD BE WORKING SINNER GESTICLY

4099
02:24:04,440 --> 02:24:07,200
WITH THE ENVIRONMENT OF THE

4100
02:24:07,200 --> 02:24:09,560
INFECTIOUS AGENTS, SO THERE'S A

4101
02:24:09,560 --> 02:24:10,280
MULTIFASCINATING QUESTION BUT

4102
02:24:10,280 --> 02:24:11,560
DOES THIS GET TO THE POINT OF

4103
02:24:11,560 --> 02:24:13,920
ARE ADDRESSING WHAT YOU ARE

4104
02:24:13,920 --> 02:24:14,320
ASKING.

4105
02:24:14,320 --> 02:24:15,720
>>YEAH, IT'S JUST, YOU
KNOW I

4106
02:24:15,720 --> 02:24:17,760
GUESS I'M EVEN WONDERING ARE

4107
02:24:17,760 --> 02:24:19,520
THERE INVESTIGATORS LOOKING AT

4108
02:24:19,520 --> 02:24:21,600
HOW SOME OF THESE CHANGES IN

4109
02:24:21,600 --> 02:24:24,040
ENVIRONMENTAL EXPOSURES AS A

4110
02:24:24,040 --> 02:24:26,200
RESULT OF CLIMATE CHANGE

4111
02:24:26,200 --> 02:24:30,200
INTERSECT WITH INFECTION TO

4112
02:24:30,200 --> 02:24:33,080
FURTHER ALTER PREGNANCY OUTCOMES

4113
02:24:33,080 --> 02:24:36,520
INCLUDING LONG-TERM OUTCOMES ON

4114
02:24:36,520 --> 02:24:36,880
OFFSPRING.

4115
02:24:36,880 --> 02:24:40,280
>>YEAH, I SEE THAT GWEN
HAS

4116
02:24:40,280 --> 02:24:41,920
JUST UNMUTED HERSELF, SO GO

4117
02:24:41,920 --> 02:24:42,120
AHEAD.

4118
02:24:42,120 --> 02:24:43,040
>>MY ANSWER TO QUESTION
IS IT

4119
02:24:43,040 --> 02:24:44,120
THERE ARE THERE ARE NOT ENOUGH

4120
02:24:44,120 --> 02:24:48,640
AND I THINK YOU'VE IDENTIFIED

4121
02:24:48,640 --> 02:24:56,960
SOME VERY RELEVANT INTERSECTING

4122
02:24:56,960 --> 02:24:58,160
HYPOTHESIS WE THINK ABOUT THIS

4123
02:24:58,160 --> 02:25:01,320
IN THE SYSTEMS AND EVERYTHING

4124
02:25:01,320 --> 02:25:02,760
YOU DESCRIBE INTERACTS WITH EACH

4125
02:25:02,760 --> 02:25:04,480
OTHER, SO COMMUNITIES THAT MOST

4126
02:25:04,480 --> 02:25:06,840
AT RISK FOR ONGOING IMPACTS OF

4127
02:25:06,840 --> 02:25:08,040
CLIMATE AND NEED TO CONSIDER

4128
02:25:08,040 --> 02:25:09,920
WHAT THE FUTURE CLIMATE IMPACTS

4129
02:25:09,920 --> 02:25:13,120
MIGHT BE ALL HAVE ENVIRONMENTAL

4130
02:25:13,120 --> 02:25:14,480
EXPOSURES, ENVIRONMENTAL JUSTICE

4131
02:25:14,480 --> 02:25:16,840
PROBLEMS PEOPLE WHO HAVE

4132
02:25:16,840 --> 02:25:17,880
CORMORBID CONDITIONS THEY ALIGN

4133
02:25:17,880 --> 02:25:20,160
WITH LOTS OF COMMUNITIES THAT

4134
02:25:20,160 --> 02:25:21,720
WE'RE VULNERABLE DUE TO COVID,

4135
02:25:21,720 --> 02:25:24,960
SO, YEAH, WE NEED MORE PEOPLE TO

4136
02:25:24,960 --> 02:25:27,000
STUDY THIS AND OUR NOSI UP THERE

4137
02:25:27,000 --> 02:25:30,080
IS 1 WAY FOR US TO GET STARTED

4138
02:25:30,080 --> 02:25:30,800
LETTING THE COMMUNITY KNOW THAT

4139
02:25:30,800 --> 02:25:32,160
WE WOULD LOVE TO SEE MORE

4140
02:25:32,160 --> 02:25:33,560
APPLICATIONS ABOUT YOU WE ALSO

4141
02:25:33,560 --> 02:25:34,840
THINK IT'S PRETTY COMPLICATED

4142
02:25:34,840 --> 02:25:36,120
AND WILL PROBABLY NEED TO BRING

4143
02:25:36,120 --> 02:25:37,720
NEW PEOPLE TO THE TABLE LIKE

4144
02:25:37,720 --> 02:25:38,640
CLIMATE SCIENTISTS AND OTHER WHO

4145
02:25:38,640 --> 02:25:40,680
IS CAN REALLY WORK TOGETHER WITH

4146
02:25:40,680 --> 02:25:42,440
A TEAM,A PROACH AND HOPE TO BE

4147
02:25:42,440 --> 02:25:44,760
ABLE TO BUILD CENTERS OR OTHER

4148
02:25:44,760 --> 02:25:46,280
KINDS OF TEAM SCIENCE ACTIVITIES

4149
02:25:46,280 --> 02:25:47,120
IN THE FUTURE.

4150
02:25:47,120 --> 02:25:47,480
>>THANK YOU.

4151
02:25:47,480 --> 02:25:50,040
>>ALSO KEEP IN MIND, ALL
THOSE

4152
02:25:50,040 --> 02:25:51,320
INDIRECT EFFECTS OF CLIMATE

4153
02:25:51,320 --> 02:25:55,160
CHANGE INCLUDING, I MEAN I CAN'T

4154
02:25:55,160 --> 02:25:56,080
IMAGINE THE PSYCHOSOCIAL STRESS

4155
02:25:56,080 --> 02:25:57,760
WITH THE FAMILIES AND

4156
02:25:57,760 --> 02:25:59,160
INDIVIDUALS IN PUERTO RICO, I

4157
02:25:59,160 --> 02:26:00,880
MEAN GOING, I DON'T KNOW, DO

4158
02:26:00,880 --> 02:26:02,720
THEY HAVE POWER YET?

4159
02:26:02,720 --> 02:26:05,400
I CAN'T EVEN IMAGINE WHAT THE

4160
02:26:05,400 --> 02:26:06,520
PSYCHOSOCIAL STRESS IS AND HOW

4161
02:26:06,520 --> 02:26:08,920
IT'S AFCING THEM AND HOW IT'S

4162
02:26:08,920 --> 02:26:09,840
COMPROMISING THEIR IMMUNE SYSTEM

4163
02:26:09,840 --> 02:26:12,600
WHICH CAN MAKE THEM MORE

4164
02:26:12,600 --> 02:26:13,640
SUSCEPTIBILITY TO INFECTIOUS

4165
02:26:13,640 --> 02:26:14,600
AGENTS.

4166
02:26:14,600 --> 02:26:24,320
SO IT'S SO MULTIFACTORIAL.

4167
02:26:24,320 --> 02:26:25,080
IT'S A COLLABORATIVE EFFORT AND

4168
02:26:25,080 --> 02:26:27,760
WE HAVE TO ADDRESS ALL OF THESE,

4169
02:26:27,760 --> 02:26:29,880
FROM SMOKING TO WILDFIRES,

4170
02:26:29,880 --> 02:26:30,840
HURRICANES, YOU KNOW NOT ONLY

4171
02:26:30,840 --> 02:26:34,560
WIND TISSUE CULTURE MEDIA BUT

4172
02:26:34,560 --> 02:26:36,280
THE FLOODING ASSOCIATED WITH

4173
02:26:36,280 --> 02:26:37,600
HURRICANES AND DISTRIBUTION,

4174
02:26:37,600 --> 02:26:40,200
THERE ARE--WHEN YOU LOOK AT

4175
02:26:40,200 --> 02:26:41,480
STATISTICS IT'S REMARKABLE HOW

4176
02:26:41,480 --> 02:26:44,720
MANY OF THESE SUPER FUN SITES

4177
02:26:44,720 --> 02:26:46,360
ARE LOCATED IN A PLACE WHERE

4178
02:26:46,360 --> 02:26:47,440
THEY'RE POTENTIALLY AT RISK OF

4179
02:26:47,440 --> 02:26:49,600
FLOODING AND THE DISTRIBUTING

4180
02:26:49,600 --> 02:26:51,360
SOME OF THESE AGENT INTOS THE

4181
02:26:51,360 --> 02:26:52,200
SURROUNDING COMMUNITIES AND THEN

4182
02:26:52,200 --> 02:26:53,520
OF COURSE THE NET EFFECT IN THE

4183
02:26:53,520 --> 02:26:58,080
END IS YOU HAVE NOW IN MANY

4184
02:26:58,080 --> 02:26:58,920
COMMUNITIES OF COLOR THAT DON'T

4185
02:26:58,920 --> 02:27:00,920
HAVE THE OPTION OF MOVING INTO A

4186
02:27:00,920 --> 02:27:02,000
NONFLOOD PLAIN AREA, YOU KNOW

4187
02:27:02,000 --> 02:27:04,080
THEIR HOMES ARE POTENT IMRALLY

4188
02:27:04,080 --> 02:27:06,320
GOING TO BE FULL OF MOLD AS A

4189
02:27:06,320 --> 02:27:08,160
RESULT OF FLOODING SO WE HAVE

4190
02:27:08,160 --> 02:27:10,000
STOD THESE EFFECTS SO LOTS OF

4191
02:27:10,000 --> 02:27:11,400
DIFFERENT THINGS SO THANKS FOR

4192
02:27:11,400 --> 02:27:14,800
YOUR QUESTION, IT WAS REALLY

4193
02:27:14,800 --> 02:27:15,600
APPRECIATED.

4194
02:27:15,600 --> 02:27:17,840
>>THANK YOU SABRA, LOOKS
LIKE

4195
02:27:17,840 --> 02:27:21,640
DR. ROBINSON ALSO HAS A

4196
02:27:21,640 --> 02:27:22,800
QUESTION.

4197
02:27:22,800 --> 02:27:24,160
THERE SHE IS,.

4198
02:27:24,160 --> 02:27:28,320
>>YEAH, THANK YOU FOR A
VERY

4199
02:27:28,320 --> 02:27:29,320
INFORM PFAATIVE PRESENTATION,

4200
02:27:29,320 --> 02:27:30,840
YOUR WORK CLEARLY CUTS ACROSS A

4201
02:27:30,840 --> 02:27:33,560
LOT OF WHAT MOST OF US DO SO MY

4202
02:27:33,560 --> 02:27:37,360
QUESTION IS A LITTLE BIT OF AN

4203
02:27:37,360 --> 02:27:39,400
EXTENSION OF SABRA'S QUESTION,

4204
02:27:39,400 --> 02:27:41,360
TYPICALLY WE LOOK AT DISEASE AND

4205
02:27:41,360 --> 02:27:45,840
OUTCOMES AND WE MOVE TO

4206
02:27:45,840 --> 02:27:46,800
PREVENTION BUT AT THE INDIVIDUAL

4207
02:27:46,800 --> 02:27:48,800
LEVEL, WHAT ARE THINGS THAT ARE

4208
02:27:48,800 --> 02:27:51,920
BEING DONE OR PRACTITIONERS CAN

4209
02:27:51,920 --> 02:27:54,040
ADVICE THEIR PATIENTINGS IN A

4210
02:27:54,040 --> 02:27:54,680
PREVENTION MODE BECAUSE

4211
02:27:54,680 --> 02:28:00,880
INDIVIDUALS CAN BE THE CONTROL

4212
02:28:00,880 --> 02:28:02,440
THE CLIMATE WE KNOW THERE ARE

4213
02:28:02,440 --> 02:28:03,520
FAR REACHING IMPACTS SO WHAT DO

4214
02:28:03,520 --> 02:28:05,160
WE TELL PEOPLE AT THE INDIVIDUAL

4215
02:28:05,160 --> 02:28:07,000
LEVEL, IS THERE WORK DONE THERE,

4216
02:28:07,000 --> 02:28:08,560
ARE THERE PREVENTION TECHNIQUES

4217
02:28:08,560 --> 02:28:09,640
WE CAN GIVE PATIENTS AND IS

4218
02:28:09,640 --> 02:28:16,200
THERE MORE WORK TO BE DONE IN

4219
02:28:16,200 --> 02:28:16,800
THAT AREA?

4220
02:28:16,800 --> 02:28:19,880
WELL, I WILL ASK FOR DR. COLLMAN

4221
02:28:19,880 --> 02:28:22,840
TO WEIGH IN HERE BUT AS A

4222
02:28:22,840 --> 02:28:25,480
COMMUNITY WHAT CAN WE DO TO

4223
02:28:25,480 --> 02:28:27,000
PROMOTE RESILIENCE WITHIN

4224
02:28:27,000 --> 02:28:28,520
COMMUNITIES, ALSO 1 OF THINGS

4225
02:28:28,520 --> 02:28:30,480
BROADLY ACROSS THE VIERPTAL

4226
02:28:30,480 --> 02:28:33,920
HEALTH SCIENCES IS GETTING

4227
02:28:33,920 --> 02:28:35,400
MESSAGING TO POSITIONS, WHAT DO

4228
02:28:35,400 --> 02:28:37,400
PHYSICIANS TELL THEIR PATIENTS,

4229
02:28:37,400 --> 02:28:39,920
FOR EXAMPLE, ABOUT FFAS, PFAS IS

4230
02:28:39,920 --> 02:28:43,800
IN THE NEWS SO WHAT DO WE TELL

4231
02:28:43,800 --> 02:28:45,240
PEOPLE, PATIENTS ABOUT FFAS

4232
02:28:45,240 --> 02:28:46,520
EXPOSURE, FOR EXAMPLE IF YOU ARE

4233
02:28:46,520 --> 02:28:49,080
MEG PRABT YOU DON'T WANT TO GO

4234
02:28:49,080 --> 02:28:51,080
SPRAYING THOSE PFAS CHEMICALS ON

4235
02:28:51,080 --> 02:28:52,600
YOUR HIKING BOOTS AND BREATHING

4236
02:28:52,600 --> 02:29:01,400
THOSE VAPORS IN, SO CREATING

4237
02:29:01,400 --> 02:29:02,600
THOSE MESSAGES ABOUT VIERMAL

4238
02:29:02,600 --> 02:29:04,120
EXPOSURES AND HEALTH IS THE

4239
02:29:04,120 --> 02:29:06,080
SECOND THEME OF OUR STRATEGIC

4240
02:29:06,080 --> 02:29:07,480
PLAN, BECAUSE PACKAGING UP THE

4241
02:29:07,480 --> 02:29:08,800
INFORMATION, THE HEALTH RISKS

4242
02:29:08,800 --> 02:29:11,120
THAT WE'RE AWARE OF, YOU KNOW

4243
02:29:11,120 --> 02:29:12,520
PREVENTION STRATEGIES THAT WE

4244
02:29:12,520 --> 02:29:16,720
CAN DEPLOY, AND THEN CREATING

4245
02:29:16,720 --> 02:29:17,560
MESSAGES FOR PHYSICIANS.

4246
02:29:17,560 --> 02:29:21,720
I MEAN 1 OF THE GREAT

4247
02:29:21,720 --> 02:29:24,200
FRUSTRATIONS I HAVE IS THAT MOST

4248
02:29:24,200 --> 02:29:25,000
PHYSICIANS NEVER ASK THEIR

4249
02:29:25,000 --> 02:29:25,920
PATIENTS WHERE DO YOU LIVE AND

4250
02:29:25,920 --> 02:29:27,400
WHERE DO YOU WORK.

4251
02:29:27,400 --> 02:29:29,520
SO WE NEED TO CHANGE THAT.

4252
02:29:29,520 --> 02:29:31,760
WE NEED TO START GETTING

4253
02:29:31,760 --> 02:29:32,840
PHYSICIANS TO ASK THE QUESTIONS

4254
02:29:32,840 --> 02:29:35,840
SO THAT THEY CAN BE MORE AWARE

4255
02:29:35,840 --> 02:29:37,120
OF POTENTIAL ENVIRONMENTAL

4256
02:29:37,120 --> 02:29:39,320
EXPOSURES THAT CAN IMPACT HUMAN

4257
02:29:39,320 --> 02:29:40,400
HEALTH.

4258
02:29:40,400 --> 02:29:41,840
NG WEENK I SEE YOU UNMUTED, DO

4259
02:29:41,840 --> 02:29:44,400
YOU WANT TO ADD TO THIS?

4260
02:29:44,400 --> 02:29:45,320
>>WELL, DOCTOR, I NOTICED
THE

4261
02:29:45,320 --> 02:29:48,040
TIME HERE AND I WANT TO BE

4262
02:29:48,040 --> 02:29:49,320
RESPECTFUL OF YOUR AGENDA YOU

4263
02:29:49,320 --> 02:29:50,760
CAN DECIDE IF YOU WANT ANOTHER

4264
02:29:50,760 --> 02:29:51,560
ANSWER TO THEY--THE SO IF YOU

4265
02:29:51,560 --> 02:29:52,760
WANT TO MOVE ON.

4266
02:29:52,760 --> 02:29:58,520
>>THANKS SO MUCH GWEN IF
WE

4267
02:29:58,520 --> 02:29:59,720
COULD LET THE DOCTOR ASK HER

4268
02:29:59,720 --> 02:30:01,000
QUESTION AND CLOSE OUT THIS

4269
02:30:01,000 --> 02:30:01,240
SECTION.

4270
02:30:01,240 --> 02:30:03,040
THANK YOU SO MUCH GWEN FOR YOUR

4271
02:30:03,040 --> 02:30:04,680
GRACE, THERE, DID YOU HAVE A

4272
02:30:04,680 --> 02:30:05,840
QUESTION?

4273
02:30:05,840 --> 02:30:06,880
>>YES, GOOD MORNING,
EVERYBODY,

4274
02:30:06,880 --> 02:30:12,480
SO MY QUESTION IS, ACTUALLY PART

4275
02:30:12,480 --> 02:30:15,560
OF THE DISCUSSION THAT JUST TOOK

4276
02:30:15,560 --> 02:30:21,560
PLACE, I WAS WONDERING WHAT

4277
02:30:21,560 --> 02:30:23,000
NIEHS IS DOING ENCOURAGING

4278
02:30:23,000 --> 02:30:26,080
MEDICAL SCHOOLS, NURSING SCHOOLS

4279
02:30:26,080 --> 02:30:28,040
TO ACTUALLY TRAIN HEALTHCARE

4280
02:30:28,040 --> 02:30:30,720
PROVIDERS WHO ARE IN TRAINING,

4281
02:30:30,720 --> 02:30:35,120
YOU KNOW AND TRAIN THEM INTO

4282
02:30:35,120 --> 02:30:35,680
ENVIRONMENTAL HEALTH ISSUES?

4283
02:30:35,680 --> 02:30:38,000
BECAUSE I THINK AT THIS POINT

4284
02:30:38,000 --> 02:30:46,400
WHERE IT'S BECOMES ALMOST LIKE

4285
02:30:46,400 --> 02:30:47,680
EXSTENTIAL ISSUE FOR EVERYONE IN

4286
02:30:47,680 --> 02:30:49,960
THE WORLD ACTUALLY, IT'S REALLY

4287
02:30:49,960 --> 02:30:53,040
VERY IMPORTANT TO START TRAINING

4288
02:30:53,040 --> 02:30:54,200
OUR HEALTHCARE PROFESSIONALS

4289
02:30:54,200 --> 02:31:04,200
WHEN THEY ARE IN TRAINING.

4290
02:31:04,200 --> 02:31:06,600
SOY I WILL STOP HERE.

4291
02:31:06,600 --> 02:31:08,600
>>I WILL START OFF BY
SAYING WE

4292
02:31:08,600 --> 02:31:10,000
HAVE SPECIFIC PROGRAMS, GWEN DO

4293
02:31:10,000 --> 02:31:12,120
YOU WANT TO CHIME IN HERE, WE

4294
02:31:12,120 --> 02:31:13,160
HAVE SPECIFIC PROGRAMS WHERE WE

4295
02:31:13,160 --> 02:31:15,240
GET IN AND TRAIN PEDIATRICIANS

4296
02:31:15,240 --> 02:31:15,960
AND HEALTHCARE PROFESSIONALS.

4297
02:31:15,960 --> 02:31:17,880
JUST OVER ALL INCREASING THE

4298
02:31:17,880 --> 02:31:20,160
AWARENESS THAT THE ENVIRONMENTAL

4299
02:31:20,160 --> 02:31:21,000
EXPOSURES MAKE PEOPLE 6.

4300
02:31:21,000 --> 02:31:23,560
AND IT'S NOT JUST THOSE GENE

4301
02:31:23,560 --> 02:31:25,080
VARIANTS THAT THEY INHERIT IN

4302
02:31:25,080 --> 02:31:26,800
THEIR PARENTS ALONG THE LINES OF

4303
02:31:26,800 --> 02:31:31,440
THE PRECISION MEDICINE PROGRAM,

4304
02:31:31,440 --> 02:31:32,880
BUT BRINGING BRINGING

4305
02:31:32,880 --> 02:31:33,920
ENVIRONMENTAL EXPOSURES AND

4306
02:31:33,920 --> 02:31:36,200
FACTORING IT INTO THE EQUATION,

4307
02:31:36,200 --> 02:31:38,440
SO IT'S BEEN A PASSION OF OURS

4308
02:31:38,440 --> 02:31:39,840
AND A PERSONAL PASSION OF MINE

4309
02:31:39,840 --> 02:31:44,200
IS REALLY BRINGING ENVIRONMENTAL

4310
02:31:44,200 --> 02:31:45,440
EXPOSURES INTO STUDYING THE

4311
02:31:45,440 --> 02:31:46,920
ETIOLOGY OF HUMAN DISEASE.

4312
02:31:46,920 --> 02:31:51,000
O GWEN DO YOU WANT TO TALK ABOUT

4313
02:31:51,000 --> 02:31:51,680
THESE SPECIFIC PROGRAMS?

4314
02:31:51,680 --> 02:31:53,840
>>SO ONLY THING I WOULD
ADD IS

4315
02:31:53,840 --> 02:31:56,200
NIH LAUNCHED PEDEIATED RICK AND

4316
02:31:56,200 --> 02:31:56,960
REPRODUCTIVE FELLOWS PROGRAM,

4317
02:31:56,960 --> 02:32:00,480
SCHOLARS PROGRAM THAT IS TO

4318
02:32:00,480 --> 02:32:02,080
PROVIDE TRAINING AWARENESS.

4319
02:32:02,080 --> 02:32:04,200
WE WORK COLLABORATIVELY WITH THE

4320
02:32:04,200 --> 02:32:06,560
CDC AND EPA ON PEDIATRIC

4321
02:32:06,560 --> 02:32:07,360
ENVIRONMENTAL HEALTH SPECIALTY

4322
02:32:07,360 --> 02:32:09,680
UNITS WITH LONG STANDING WORK IN

4323
02:32:09,680 --> 02:32:10,720
THE CHILDREN'S ENVIRONMENTAL

4324
02:32:10,720 --> 02:32:13,360
HEALTH SPACE, IN MANY OF OUR

4325
02:32:13,360 --> 02:32:15,080
CENTERS PROGRAMS AT THE

4326
02:32:15,080 --> 02:32:17,360
INSTITUTE WE EMBED WITHIN THEM

4327
02:32:17,360 --> 02:32:19,320
THE OPPORTUNITY FOR PHYSICIANS

4328
02:32:19,320 --> 02:32:20,640
OR OTHER HEALTH PRACTITIONERS

4329
02:32:20,640 --> 02:32:23,280
NOT JUST PHYSICIANS, YOU KNOW

4330
02:32:23,280 --> 02:32:26,320
COMMUNITY HEALTH WORKERS,

4331
02:32:26,320 --> 02:32:27,520
[INDISCERNIBLE], NURSES, AND

4332
02:32:27,520 --> 02:32:29,240
EVEN PHARMACISTS, YOU KNOW IN

4333
02:32:29,240 --> 02:32:30,760
THIS WHOLE GAMUT OF BUILDING

4334
02:32:30,760 --> 02:32:31,080
AWARENESS.

4335
02:32:31,080 --> 02:32:34,480
SO WE SEE THAT AS IMPORTANT

4336
02:32:34,480 --> 02:32:35,200
STAKEHOLDERS AND INTEGRATED IN

4337
02:32:35,200 --> 02:32:39,760
THAT, AND OF COURSE WE HAVE

4338
02:32:39,760 --> 02:32:40,320
TRADITIONAL TRAINING GRANTS.

4339
02:32:40,320 --> 02:32:41,200
OFTEN TIMES WE DO HAVE

4340
02:32:41,200 --> 02:32:42,520
PHYSICIANS WHO ARE INTERESTED IN

4341
02:32:42,520 --> 02:32:44,800
THE RESEARCH TRAINING ASPECTS

4342
02:32:44,800 --> 02:32:46,360
AND MOVE HERE, BUT ACTUALLY LONG

4343
02:32:46,360 --> 02:32:50,440
TIME AGO, WE HAD A PROGRAM THAT

4344
02:32:50,440 --> 02:32:51,840
WAS SPECIFICALLY BUILDING

4345
02:32:51,840 --> 02:32:53,160
CURRICULA WITHIN MEDICAL SCHOOLS

4346
02:32:53,160 --> 02:32:55,200
AND YOU KNOW THAT WAS 20 YEARS

4347
02:32:55,200 --> 02:32:55,440
AGO.

4348
02:32:55,440 --> 02:32:57,680
SO MAYBE WE WERE AHEAD OF THE

4349
02:32:57,680 --> 02:32:59,880
CURVE, AND IN SOME OF THOSE

4350
02:32:59,880 --> 02:33:02,200
PROGRAMS, THESE THINGS HAVE

4351
02:33:02,200 --> 02:33:04,720
CONTINUED TO FLOURISH AND MORE

4352
02:33:04,720 --> 02:33:06,480
UNIVERSITIES HAVE REALIZED THE

4353
02:33:06,480 --> 02:33:07,440
PERSON OF ENVIRONMENTAL EXPHELGT

4354
02:33:07,440 --> 02:33:09,560
HAVE INCLUDED THEM IN THE

4355
02:33:09,560 --> 02:33:10,160
CURRICULA.

4356
02:33:10,160 --> 02:33:12,000
WE WORK CLOSELY WITH MEDICAL

4357
02:33:12,000 --> 02:33:13,160
SOCIETIES, PEDIATRICS ACADEMY

4358
02:33:13,160 --> 02:33:15,760
AND THE CLIMATE CHANGE SPACE,

4359
02:33:15,760 --> 02:33:17,640
THERE ARE QUITE A NUMBER OF

4360
02:33:17,640 --> 02:33:18,600
ORGANIZATIONS POPPING UP WITHIN

4361
02:33:18,600 --> 02:33:21,640
THESE AND IN BETWEEN THESE TO

4362
02:33:21,640 --> 02:33:24,960
REALLY WORK ON THE ISSUE OF

4363
02:33:24,960 --> 02:33:27,200
PHYSICIAN KNOWLEDGE BASE AND

4364
02:33:27,200 --> 02:33:29,440
THEM BEING RARE INFLUENCERS AND

4365
02:33:29,440 --> 02:33:31,840
PRACTITIONERS WHO CAN PUSH THE

4366
02:33:31,840 --> 02:33:33,680
SUSTAINABILITY GOALS AND CLIMATE

4367
02:33:33,680 --> 02:33:34,960
CHANGE AGENDA WITHIN THEIR

4368
02:33:34,960 --> 02:33:37,920
SPHERES OF INFLUENCE, SO, I

4369
02:33:37,920 --> 02:33:39,080
THINK IT'S--IT'S--WE'RE HAPPY

4370
02:33:39,080 --> 02:33:41,120
ABOUT THAT AND WE IN OUR CLIMATE

4371
02:33:41,120 --> 02:33:42,320
CHANGE PROGRAM ARE TRYING TO

4372
02:33:42,320 --> 02:33:43,600
LEVERAGE ALL OF THOSE

4373
02:33:43,600 --> 02:33:45,360
OPPORTUNITIES AND BUILD

4374
02:33:45,360 --> 02:33:50,600
PARTNERSHIPS WITH THOSE NEWLY

4375
02:33:50,600 --> 02:33:51,000
EMERGING GROUPS.

4376
02:33:51,000 --> 02:33:53,080
THANK YOU FOR YOUR WORK - AND WE

4377
02:33:53,080 --> 02:33:54,960
APPRECIATE THE SUPPORT THAT THE

4378
02:33:54,960 --> 02:33:56,960
ORWH HAS GIVEN TO OUR CLIMATE

4379
02:33:56,960 --> 02:34:02,080
CHANGE RECENTLY WITH THE AWARD

4380
02:34:02,080 --> 02:34:02,440
OF SUPPLEMENTS.

4381
02:34:02,440 --> 02:34:06,280
>>THANK YOU SO MUCH FOR
JOINING

4382
02:34:06,280 --> 02:34:08,880
US DR. COLLMAN, AND RICK FOR AN

4383
02:34:08,880 --> 02:34:09,960
AMAZING WHIRL WIND PRESENTATION,

4384
02:34:09,960 --> 02:34:11,560
I DID ASK YOU TO COVER A LOT AND

4385
02:34:11,560 --> 02:34:12,880
YOU FOUND A WAY TO DO IT SO

4386
02:34:12,880 --> 02:34:14,400
THANK YOU SO MUCH FOR THAT.

4387
02:34:14,400 --> 02:34:17,160
WE ARE SO EXCITED THAT THIS

4388
02:34:17,160 --> 02:34:18,120
ACCESS ENVIRONMENT COMMITTEE

4389
02:34:18,120 --> 02:34:19,480
MEETING HAS ENVIRONMENTAL HEALTH

4390
02:34:19,480 --> 02:34:20,040
AS HAY THEME.

4391
02:34:20,040 --> 02:34:21,520
IT IS SO IMPORTANT AND BOTH OF

4392
02:34:21,520 --> 02:34:22,560
YOU OUGHT LINED WHY IT'S SO

4393
02:34:22,560 --> 02:34:24,560
IMPORTANT AND WE REAMLY LOOK

4394
02:34:24,560 --> 02:34:26,160
FORWARD TO EXPANDING OUR

4395
02:34:26,160 --> 02:34:27,640
COLLABORATION WITH YOU GOING

4396
02:34:27,640 --> 02:34:27,880
FORWARD.

4397
02:34:27,880 --> 02:34:30,000
WE HAVE A COUPLE IDEAS FROM

4398
02:34:30,000 --> 02:34:31,280
THESE QUESTIONS SO GWEN I WILL

4399
02:34:31,280 --> 02:34:32,440
BE FOLLOWING UP ON THOSE AND

4400
02:34:32,440 --> 02:34:34,560
THANK YOU RICK FOR JOINING US SO

4401
02:34:34,560 --> 02:34:40,680
MUCH, WE APPRECIATE YOU BOTH.

4402
02:34:40,680 --> 02:34:41,480
>>AGAIN, THANKS FOR THE

4403
02:34:41,480 --> 02:34:42,080
OPPORTUNITY.

4404
02:34:42,080 --> 02:34:42,480
IT'S MY PLEASURE.

4405
02:34:42,480 --> 02:34:43,840
WE LOOK FORWARD TO MORE

4406
02:34:43,840 --> 02:34:44,320
CLOOBERATIONS WITH YOU.

4407
02:34:44,320 --> 02:34:47,760
YOU ARE DOING A GREAT JOB BY THE

4408
02:34:47,760 --> 02:34:48,120
WAY.

4409
02:34:48,120 --> 02:34:49,000
I'M REALLY IMPRESSED WITH THE

4410
02:34:49,000 --> 02:34:50,080
LEADERSHIP YOU ARE BRINGING TO

4411
02:34:50,080 --> 02:34:50,800
THE OFFICE.

4412
02:34:50,800 --> 02:34:53,160
THANK YOU RICK, VERY KIND OF

4413
02:34:53,160 --> 02:34:53,360
YOU.

4414
02:34:53,360 --> 02:34:54,080
THANKS, GWEN.

4415
02:34:54,080 --> 02:34:54,960
>>THANKS EVERYONE.

4416
02:34:54,960 --> 02:34:55,320
>>BE WELL.

4417
02:34:55,320 --> 02:34:58,960
>>SO WITH THAT, WE HAVE A
HALF

4418
02:34:58,960 --> 02:35:00,360
AN HOUR, LITTLE BIT LESS THAN A

4419
02:35:00,360 --> 02:35:01,800
HALF OUR LEFT FOR OPEN

4420
02:35:01,800 --> 02:35:04,080
DISCUSSION AND IN RESPONSE TO

4421
02:35:04,080 --> 02:35:06,600
YOUR FEEDBACK IN THE PAST WE

4422
02:35:06,600 --> 02:35:08,280
OPENED UP DISCUSSION SLOTS, BOTH

4423
02:35:08,280 --> 02:35:11,520
IN THE MORNING AND AFTERNOON AND

4424
02:35:11,520 --> 02:35:15,080
I WOULD ASK THAT OUR MEMBERS IF

4425
02:35:15,080 --> 02:35:17,520
YOU'RE ABLE TO GO AHEAD, I KNOW

4426
02:35:17,520 --> 02:35:19,400
WE TOLD YOU TO TURN OFF YOUR

4427
02:35:19,400 --> 02:35:20,720
CAMERAS, BUT WE ARE OKAY, IF YOU

4428
02:35:20,720 --> 02:35:23,120
WILL PUT YOUR CAMERAS ON FOR THE

4429
02:35:23,120 --> 02:35:24,040
DISCUSSION THAT WILL WOULD BE

4430
02:35:24,040 --> 02:35:27,280
GREAT TO BE ABLE TO SEE YOUR

4431
02:35:27,280 --> 02:35:30,360
BEAUTIFUL FACES, JUST TO BE ABLE

4432
02:35:30,360 --> 02:35:32,120
TO INTERACT A BIT MORE DIRECTLY.

4433
02:35:32,120 --> 02:35:35,000
SO THANK YOU SO MUCH.

4434
02:35:35,000 --> 02:35:37,640
JUST SO SO THRILLED TO SEE OUR

4435
02:35:37,640 --> 02:35:39,200
NEW MEMBERS, RETURNING MEMBERS,

4436
02:35:39,200 --> 02:35:42,120
YOU ARE ALL NOT SHRINKING

4437
02:35:42,120 --> 02:35:44,000
VIOLETS, SABRA WE WOULD NEVER

4438
02:35:44,000 --> 02:35:46,120
SAY YOU'RE A SHRINKING VIOLET OR

4439
02:35:46,120 --> 02:35:47,400
ANY OF YOU BECAUSE YOU'RE SO

4440
02:35:47,400 --> 02:35:49,280
COMMITTED TO THE WOMEN'S HEALTH

4441
02:35:49,280 --> 02:35:51,520
AND IN THE MISSION AREA OF YOUR

4442
02:35:51,520 --> 02:35:52,440
PARTICULAR DISCIPLINE AND YOUR

4443
02:35:52,440 --> 02:35:54,960
ORGANIZATION SO I KNOW THAT YOU

4444
02:35:54,960 --> 02:35:57,200
HAVE IDEAS AND THOUGHTS AND

4445
02:35:57,200 --> 02:35:58,000
WELCOME DR. SHARP'S DELIGHTED TO

4446
02:35:58,000 --> 02:35:59,720
HAVE YOU WITH US, SO THIS PERIOD

4447
02:35:59,720 --> 02:36:03,600
OF TIME IS OPEN.

4448
02:36:03,600 --> 02:36:04,840
FOR DIGS CUSHION, WE WANT TO

4449
02:36:04,840 --> 02:36:06,600
UNDERSTAND WHAT'S ON YOUR MIND,

4450
02:36:06,600 --> 02:36:09,000
WHAT YOU THINK ORWH SHOULD KNOW

4451
02:36:09,000 --> 02:36:11,800
ABOUT, AND THE CONTEXT OF OUR

4452
02:36:11,800 --> 02:36:13,160
MISSION AREAS, INCLUSION,

4453
02:36:13,160 --> 02:36:14,560
WOMEN'S HEALTH, SEX, GENDER,

4454
02:36:14,560 --> 02:36:17,560
CAREERS AND ANY TOPIC THAT'S A

4455
02:36:17,560 --> 02:36:18,760
TOPIC UNDER OUR MISSION IS OPEN.

4456
02:36:18,760 --> 02:36:29,240
SO WHO WOULD LIKE TO START?

4457
02:36:34,120 --> 02:36:34,960
>>I KNEW IT DR. KLEIN.

4458
02:36:34,960 --> 02:36:37,440
>>YOU KNOW I CAN BE THE

4459
02:36:37,440 --> 02:36:40,880
REMEMBER ALL OF THE INSTITUTES

4460
02:36:40,880 --> 02:36:46,440
WHO ARE ENGAGED IN ORWH PROGRAMS

4461
02:36:46,440 --> 02:36:50,160
SO COULD YOU CHOOSE TO REMIND US

4462
02:36:50,160 --> 02:36:52,240
IF NIEHS IS 1 OF THE SPONSORING

4463
02:36:52,240 --> 02:36:54,160
EN--STRATEGIESITUTES FOR THINGS

4464
02:36:54,160 --> 02:36:57,520
LIKE THE SCORE THE BIRCH, THE

4465
02:36:57,520 --> 02:37:02,080
RO-1, ANY OTHER OTHER  WONDERFUL

4466
02:37:02,080 --> 02:37:04,160
OPPORTUNITIES THAT YOU REVIEWED

4467
02:37:04,160 --> 02:37:04,440
WITH UTR.

4468
02:37:04,440 --> 02:37:05,200
>>GREAT QUESTION AND I
THINK

4469
02:37:05,200 --> 02:37:08,040
THE ANSWER IS NO FOR THE BIRCH,

4470
02:37:08,040 --> 02:37:08,560
AND THE SCORE.

4471
02:37:08,560 --> 02:37:10,040
>>I THINK IT'S NO AS
WELL.

4472
02:37:10,040 --> 02:37:11,000
>>AND I'M JUST DOUBLE
CHECKING

4473
02:37:11,000 --> 02:37:16,600
TO SEE IF THEY SIGNED ON THE SEX

4474
02:37:16,600 --> 02:37:17,680
AND GENDER RO-1 NO.

4475
02:37:17,680 --> 02:37:20,320
>>I THOUGHT THERE WAS 1
EXTRA

4476
02:37:20,320 --> 02:37:22,440
FOR THE RO-1 AND THE SCORE

4477
02:37:22,440 --> 02:37:25,080
AND/OR NIH AS SIGNED UP TO THE

4478
02:37:25,080 --> 02:37:25,520
RO-1, YES!

4479
02:37:25,520 --> 02:37:28,000
>>SO THATIA GOOD TO HEAR.

4480
02:37:28,000 --> 02:37:28,960
>>YEAH.

4481
02:37:28,960 --> 02:37:29,240
>>OKAY.

4482
02:37:29,240 --> 02:37:29,960
>>YES, RICK,.

4483
02:37:29,960 --> 02:37:32,040
>>YES, YOU SIGNED UP.

4484
02:37:32,040 --> 02:37:36,040
>>GREAT. 

4485
02:37:36,040 --> 02:37:37,360
GOOD TO HEAR.

4486
02:37:37,360 --> 02:37:39,800
SO MAYBE THIS REALLY STARTS TO

4487
02:37:39,800 --> 02:37:40,960
FOSTER MORRESEARCH SPECIFIC IN

4488
02:37:40,960 --> 02:37:42,560
THIS AREA.

4489
02:37:42,560 --> 02:37:45,000
>>YEAH AND LET ME SABRA
LET ME

4490
02:37:45,000 --> 02:37:46,000
INTERRUPT YOU BEFORE YOU GO

4491
02:37:46,000 --> 02:37:48,080
BECAUSE I JUST PULLED UP THE

4492
02:37:48,080 --> 02:37:50,080
DATA AND NIEHS ALSO SIGNED ON TO

4493
02:37:50,080 --> 02:37:53,120
THE NEW SCORE RFA.

4494
02:37:53,120 --> 02:37:54,560
>>THAT'S CORRECT.

4495
02:37:54,560 --> 02:37:54,880
>>YES.

4496
02:37:54,880 --> 02:37:57,480
>>YOU GET DOUBLE GOLD
STARS.

4497
02:37:57,480 --> 02:38:00,640
>>WELL, WE'RE FOLLOWING
YOUR

4498
02:38:00,640 --> 02:38:01,480
LEADERSHIP. 

4499
02:38:01,480 --> 02:38:02,960
>>THANK YOU.

4500
02:38:02,960 --> 02:38:04,840
>>THANK YOU SABRA, DID
YOU WANT

4501
02:38:04,840 --> 02:38:06,320
TO EXTEND THAT OR WAS YOUR

4502
02:38:06,320 --> 02:38:07,960
POINT-REAM LE THAT THESE

4503
02:38:07,960 --> 02:38:09,720
ISSUES--THERE ARE SO MANY ISSUES

4504
02:38:09,720 --> 02:38:10,800
THAT ISHT SECTIONAL ANALYSIS

4505
02:38:10,800 --> 02:38:14,560
BETWEEN ENVIRONMENTAL HEALTH AND

4506
02:38:14,560 --> 02:38:15,320
WOMEN'S HEALTH.

4507
02:38:15,320 --> 02:38:15,720
>>ABSOLUTELY.

4508
02:38:15,720 --> 02:38:16,960
>>I'M ENCOURAGED TO SEE

4509
02:38:16,960 --> 02:38:20,240
ENGAGEMENT WITH THE INSTITUTE TO

4510
02:38:20,240 --> 02:38:25,760
FOSTER MORE RESEARCH IN THESE

4511
02:38:25,760 --> 02:38:27,520
AREAS AND JUST TO KIND OF, YOU

4512
02:38:27,520 --> 02:38:30,680
KNOW SO THAT IT'S JUST NOT ORWH

4513
02:38:30,680 --> 02:38:31,880
AND NIEHS AND THAT YOU'RE

4514
02:38:31,880 --> 02:38:34,160
LIFTING ALL VOTES AND BRINGING

4515
02:38:34,160 --> 02:38:35,640
IN EXTRAMURAL INVESTIGATOR'S

4516
02:38:35,640 --> 02:38:36,320
INTO THIS DISCUSSION.

4517
02:38:36,320 --> 02:38:39,720
SO THAT WAS MY ONLY--SO,.

4518
02:38:39,720 --> 02:38:40,280
>>ABSOLUTELY.

4519
02:38:40,280 --> 02:38:43,880
AND AS YOU POINTED OUT EARLIER

4520
02:38:43,880 --> 02:38:45,160
WITH YOUR QUESTION, YOU KNOW IN

4521
02:38:45,160 --> 02:38:46,920
ORDER FOR PEOPLE TO HAVE THE

4522
02:38:46,920 --> 02:38:47,760
OPPORTUNITY TO EXPLORE SEX

4523
02:38:47,760 --> 02:38:50,160
DIFFERENCES IN THOSE AREAS,

4524
02:38:50,160 --> 02:38:52,560
THERE'S A NEED FOR THEIR TO BE A

4525
02:38:52,560 --> 02:38:57,640
FUNDING OPPORTUNITY FOR THEM TO

4526
02:38:57,640 --> 02:38:59,040
APPLY TO SO WE DO UNDERSTAND

4527
02:38:59,040 --> 02:39:02,680
THAT AND DO WANT TO THANK MY NIH

4528
02:39:02,680 --> 02:39:03,400
COLLEAGUES FOR NIEHS COLLEAGUES

4529
02:39:03,400 --> 02:39:07,680
FOR THAT AND ALSO, OUR ORWH

4530
02:39:07,680 --> 02:39:09,440
OUTREACH TO THEM, TO THEM BEING

4531
02:39:09,440 --> 02:39:10,520
THE PRIMARY LEAD FOR THEM ON

4532
02:39:10,520 --> 02:39:13,120
THAT END SO IT'S A 2 WAY STREET

4533
02:39:13,120 --> 02:39:14,920
AND WE'RE GRATEFUL TO BE WORKING

4534
02:39:14,920 --> 02:39:16,520
CLOSELY WITH THEM ON SOME OF

4535
02:39:16,520 --> 02:39:20,000
THESE ISSUES BECAUSE IT'S--THE

4536
02:39:20,000 --> 02:39:20,560
ISSUES ARE IMPORTANT.

4537
02:39:20,560 --> 02:39:23,920
AND SO I WILL MOVE ON TO

4538
02:39:23,920 --> 02:39:25,800
DR. HOLGREN WHO HAS HIS HAND UP

4539
02:39:25,800 --> 02:39:29,840
PLIGHTLY THERE.

4540
02:39:29,840 --> 02:39:30,320
SCOTT? 

4541
02:39:30,320 --> 02:39:38,240
>>YOU'RE MUTED, SCOTT.

4542
02:39:38,240 --> 02:39:39,280
>>THANK YOU JANINE.

4543
02:39:39,280 --> 02:39:41,280
I WAS SO PLEASED FOR YOUR

4544
02:39:41,280 --> 02:39:43,040
BRINGING UP TONY FAUCI TODAY AND

4545
02:39:43,040 --> 02:39:48,880
ALL THE WORK HE'S DONE FOR

4546
02:39:48,880 --> 02:39:50,840
WOMEN'S HEALTH AND IT JUST

4547
02:39:50,840 --> 02:39:53,080
REMINDS ME OF 1 OF THE PURPOSES

4548
02:39:53,080 --> 02:39:57,520
OF MYSELF ON THIS BOARD AND

4549
02:39:57,520 --> 02:40:00,360
THAT'S TO CONSTANTLY REMIND THE

4550
02:40:00,360 --> 02:40:03,000
GROUP OF THE INTEGRATION BETWEEN

4551
02:40:03,000 --> 02:40:04,200
MICROBIOLOGY AND WOMEN'S HEALTH

4552
02:40:04,200 --> 02:40:07,240
AND STILL REMAINS RELATIVELY

4553
02:40:07,240 --> 02:40:07,720
UNEXPLORED.

4554
02:40:07,720 --> 02:40:11,800
I'M GLAD THAT YOU BROUGHT UP

4555
02:40:11,800 --> 02:40:15,560
COVID AS AN EXAMPLE.

4556
02:40:15,560 --> 02:40:16,600
CERTAINLY, THERE'S A WHOLE

4557
02:40:16,600 --> 02:40:18,120
LAUNDRY LIST OF EXAMPLES AFTER

4558
02:40:18,120 --> 02:40:21,600
COVID OF HOW INFECTIOUS DISEASE

4559
02:40:21,600 --> 02:40:25,200
IMPACTS TREMENDOUSLY IMPACTS

4560
02:40:25,200 --> 02:40:28,160
WOMEN'S HEALTH AND OF COURSE,

4561
02:40:28,160 --> 02:40:30,520
WITH STUDIES ON THE MICROBIOME,

4562
02:40:30,520 --> 02:40:32,280
I MEAN THERE'S MORE PAPERS

4563
02:40:32,280 --> 02:40:34,280
COMING OUT ON MICROBIOME THAN

4564
02:40:34,280 --> 02:40:37,080
SINCE RECOMBIN ANT DNA.

4565
02:40:37,080 --> 02:40:39,880
IT'S A HUGE BUDDING FIELD AND OF

4566
02:40:39,880 --> 02:40:42,720
COURSE WE HAVE THE GUT BRAIN

4567
02:40:42,720 --> 02:40:46,080
ACCESS, GUT BLADDER ACCESS,

4568
02:40:46,080 --> 02:40:47,360
GUT-LUNG, AND ALL OF THESE

4569
02:40:47,360 --> 02:40:52,240
THINGS WHEN YOU BRIG DOWN, YOU

4570
02:40:52,240 --> 02:40:54,760
CAN REALLY FIND INTRICATE

4571
02:40:54,760 --> 02:40:56,520
CONNECTIONS WITH WOMEN'S HEALTH.

4572
02:40:56,520 --> 02:40:59,080
FOR EXAMPLE, PATIENTS OF HISTORY

4573
02:40:59,080 --> 02:41:01,960
WITH RECURRENT UTI ARE WALKING

4574
02:41:01,960 --> 02:41:03,360
AROUND WITH DECREASED DIVERSITY

4575
02:41:03,360 --> 02:41:06,360
OF THE MIKE ROY BIOME AND 1 OF

4576
02:41:06,360 --> 02:41:08,640
THE IT PURPOSE EVER THE

4577
02:41:08,640 --> 02:41:09,920
MICROBIOME IS TO PREVENT

4578
02:41:09,920 --> 02:41:11,640
PATHOGENS FROM GETTING IN, SO

4579
02:41:11,640 --> 02:41:13,080
IT'S REALLY A SYNDROME,

4580
02:41:13,080 --> 02:41:16,040
NONAPOPTOTIC THE JUST--IT'S NOT

4581
02:41:16,040 --> 02:41:18,840
JUST--IT'S A SEPARATE SYNDROME

4582
02:41:18,840 --> 02:41:22,400
AND EVEN 1 OF THE SPEAKERS

4583
02:41:22,400 --> 02:41:24,440
BRINGING UP NEURODEGENERATIVE

4584
02:41:24,440 --> 02:41:25,360
DISORDERS, PARKINSONS AND SO

4585
02:41:25,360 --> 02:41:28,440
FORTH, THERE'S PAPER COMING OUT

4586
02:41:28,440 --> 02:41:30,960
DEMONSTRATING A LINK BETWEEN

4587
02:41:30,960 --> 02:41:33,560
BACTERIAIAL INFECTION AND THINGS

4588
02:41:33,560 --> 02:41:34,880
LIKE PARKINSONS BACTERIA MAKE

4589
02:41:34,880 --> 02:41:37,560
AMLLOYDS, THE SAME STRUCTURE AS

4590
02:41:37,560 --> 02:41:39,320
AMLLOYDS THAT IMPORTANT

4591
02:41:39,320 --> 02:41:39,720
NEURODEGENERATIVE

4592
02:41:39,720 --> 02:41:40,480
PATHOPHYSIOLOGY AND THERE'S

4593
02:41:40,480 --> 02:41:42,600
PAPERS COMING OUT SHOWING THAT

4594
02:41:42,600 --> 02:41:49,080
THOSE BACTERIAL AMLLOYDS IN THE

4595
02:41:49,080 --> 02:41:50,240
GUT CAN NUCLEATE AMLLOYDS AND

4596
02:41:50,240 --> 02:41:53,200
THEY CAN STRAFUL UP THE VAGUS

4597
02:41:53,200 --> 02:41:56,400
NERVE TO THE ENTERTAIN STEM AND

4598
02:41:56,400 --> 02:41:57,040
EXACERBATE PARKINSONS SYMPTOMS,

4599
02:41:57,040 --> 02:41:59,120
SO I DON'T KNOW MY GOOD FRIEND

4600
02:41:59,120 --> 02:42:00,720
STANLEY FAL, KREBS CYCLE O SAYS

4601
02:42:00,720 --> 02:42:02,520
THAT ALL THINGS COME DOWN TOIN

4602
02:42:02,520 --> 02:42:04,360
FECTIOUS DISEASE SO I WANT TO

4603
02:42:04,360 --> 02:42:05,760
COMMEND ORWH ON DOING A

4604
02:42:05,760 --> 02:42:09,960
WONDERFUL JOB OF SUPPORTING THIS

4605
02:42:09,960 --> 02:42:12,280
AREA AS YOU'VE DONE HAD

4606
02:42:12,280 --> 02:42:13,680
HISTORICALLY AND MY LITTLE THING

4607
02:42:13,680 --> 02:42:18,720
HERE IS JUST TO THANK YOU AND

4608
02:42:18,720 --> 02:42:20,360
REMIND EVERYBODY OF THE

4609
02:42:20,360 --> 02:42:20,800
OPPORTUNITY THERE.

4610
02:42:20,800 --> 02:42:21,360
>>THANKS SCOTT.

4611
02:42:21,360 --> 02:42:26,720
I THINK THE PANDEMIC HAS

4612
02:42:26,720 --> 02:42:28,280
UNFORTUNATELY REVEALED HOW MUCH

4613
02:42:28,280 --> 02:42:30,040
MORE WE DON'T KNOW THAN WE

4614
02:42:30,040 --> 02:42:34,240
THOUGHT WE DIDN'T KNOW ABOUT

4615
02:42:34,240 --> 02:42:34,880
INFECTIOUS ORGANISMS AND THEIR

4616
02:42:34,880 --> 02:42:35,880
ISHT ACTION WITH THE ENVIRONMENT

4617
02:42:35,880 --> 02:42:38,360
AND RICK PUT A COMMENT HO IN THE

4618
02:42:38,360 --> 02:42:40,160
CHAT ABOUT HOW ENVIRONMENTAL

4619
02:42:40,160 --> 02:42:42,080
IMPACTS AFFECT THE MICROBIOME AS

4620
02:42:42,080 --> 02:42:42,440
WELL.

4621
02:42:42,440 --> 02:42:44,320
AND YOU KNOW LINDSAY TALKED

4622
02:42:44,320 --> 02:42:45,360
EARLIER ABOUT HOW COMPLICATED

4623
02:42:45,360 --> 02:42:47,120
SOME OF THESE SYSTEMS ARE AND

4624
02:42:47,120 --> 02:42:51,560
THE FACT THAT WE REALLY MUST BE

4625
02:42:51,560 --> 02:42:53,200
DESIGNING AND DEVELOPING MUCH

4626
02:42:53,200 --> 02:42:54,720
MORE COMPLEX AND NUANCED

4627
02:42:54,720 --> 02:42:59,080
STRATEGIES TO BE ABLE TO

4628
02:42:59,080 --> 02:43:02,680
INCORPORATE AND EVALUATE MORE

4629
02:43:02,680 --> 02:43:05,000
DATA WHETHER IT'S SOCIAL

4630
02:43:05,000 --> 02:43:08,760
DETERINANTS OF HELT DATA OR

4631
02:43:08,760 --> 02:43:10,160
MICROBES OR EPIGENETIC

4632
02:43:10,160 --> 02:43:10,880
MOLDIFICATIONS OR INTERACTIONS

4633
02:43:10,880 --> 02:43:12,560
AT DIFFERENT STAGES OF THE LIFE

4634
02:43:12,560 --> 02:43:13,480
COURSE AND 1 OF THE REALS THAT

4635
02:43:13,480 --> 02:43:15,040
WE PLAY AND I WOULD LO OF TO

4636
02:43:15,040 --> 02:43:17,200
HEAR FEEDBACK FROM YOU ALL ON

4637
02:43:17,200 --> 02:43:19,200
THIS, BECAUSE PART OF OUR ROLE

4638
02:43:19,200 --> 02:43:21,280
IS INTEGRATING AND CONNECTING

4639
02:43:21,280 --> 02:43:22,600
THE DOTS ACROSS THE 27

4640
02:43:22,600 --> 02:43:23,520
INSTITUTES AND CENTERS HERE,

4641
02:43:23,520 --> 02:43:26,200
THAT ARE ALL DOING AMAZING WORK

4642
02:43:26,200 --> 02:43:27,760
IN WOMEN'S HEALTH IN THE CONTEXT

4643
02:43:27,760 --> 02:43:29,720
OF THEIR MISSION AREAS AND AS WE

4644
02:43:29,720 --> 02:43:31,240
MOVE FORWARD TO DEVELOP THE

4645
02:43:31,240 --> 02:43:32,920
STRATEGIC PLAN, YOU WILL SEE

4646
02:43:32,920 --> 02:43:36,840
FROM THE PRESENTATION THIS

4647
02:43:36,840 --> 02:43:37,960
AFTERNOON WE WANT TO HEAR FROM

4648
02:43:37,960 --> 02:43:40,040
YOU IN TERMS OF ALL OF THOSE

4649
02:43:40,040 --> 02:43:42,160
MANY TOPICS, WHICH OF THEM DO WE

4650
02:43:42,160 --> 02:43:43,960
NEED TO PRIORITIZE, OKAY?

4651
02:43:43,960 --> 02:43:47,960
BECAUSE THERE'S SO MUCH WORK TO

4652
02:43:47,960 --> 02:43:50,880
BE DONE WHICH ARE SPECIFIC

4653
02:43:50,880 --> 02:43:53,400
POISED TO MOVE FORWARD WITH

4654
02:43:53,400 --> 02:43:54,400
STRATEGIC FUNDING.

4655
02:43:54,400 --> 02:43:55,920
WE ARE COMPLIMENTARY TO THE

4656
02:43:55,920 --> 02:43:58,240
ICs, WE TROO TO BE CATALYTIC,

4657
02:43:58,240 --> 02:44:00,040
WE TRY TO ADDRESS AREAS THAT

4658
02:44:00,040 --> 02:44:02,040
FALL BETWEEN THE CRACKS, TOPICS

4659
02:44:02,040 --> 02:44:02,960
THAT CROSS ICs, SO I WOULD

4660
02:44:02,960 --> 02:44:04,720
LOVE TO HEAR YOUR FEEDBACK ON

4661
02:44:04,720 --> 02:44:07,880
THAT IF ANYONE HAS COMMENTS

4662
02:44:07,880 --> 02:44:09,680
ABOUT KIND OF THE POSTURE THAT

4663
02:44:09,680 --> 02:44:11,520
ORWH WILL BE TAKING AS WE MOVE

4664
02:44:11,520 --> 02:44:12,440
FORWARD THERE BECAUSE THESE

4665
02:44:12,440 --> 02:44:14,160
ISSUES ARE COMING AUTOPSY AS WE

4666
02:44:14,160 --> 02:44:17,640
RECEIVE RESPONSES FROM THE

4667
02:44:17,640 --> 02:44:19,760
REQUEST FOR INFORMATION TO AND

4668
02:44:19,760 --> 02:44:22,240
FOR THE NEXT STRATEGIC PLAN?

4669
02:44:22,240 --> 02:44:23,360
OTHER COMMENTS?

4670
02:44:23,360 --> 02:44:27,080
SO SABRA, I WILL ASK YOU TO GO

4671
02:44:27,080 --> 02:44:28,800
AHEAD SINCE YOU'RE--

4672
02:44:28,800 --> 02:44:32,840
>>WELL, JUST FOLLOWING
OFF ON

4673
02:44:32,840 --> 02:44:34,080
SCOTT'S COMMENT, I'VE NOTED THAT

4674
02:44:34,080 --> 02:44:36,080
THE NATIONAL INSTITUTE OF ALLERG

4675
02:44:36,080 --> 02:44:37,720
EXPE INFECTIOUS DISEASES HAS NOT

4676
02:44:37,720 --> 02:44:41,160
TYPICALLY BEEN A FUNDER OVER THE

4677
02:44:41,160 --> 02:44:44,600
YEARS OF THESE INITIATIVES AND

4678
02:44:44,600 --> 02:44:47,040
KIND OF BUILDING ON YOUR

4679
02:44:47,040 --> 02:44:48,520
PRESENTATION AND YOUR COMMENTS

4680
02:44:48,520 --> 02:44:53,040
ABOUT WHAT THE COVID-19 PANDEMIC

4681
02:44:53,040 --> 02:44:53,360
HAS REVEALED.

4682
02:44:53,360 --> 02:44:56,960
IT MIGHT BE A VERY IMPORTANT

4683
02:44:56,960 --> 02:44:59,800
OPPORTUNITY TO ENGAGE OUR

4684
02:44:59,800 --> 02:45:00,960
COLLEAGUES THERE WHO HAVE FUNDED

4685
02:45:00,960 --> 02:45:03,160
THIS TYPE OF RESEARCH INCLUDING

4686
02:45:03,160 --> 02:45:05,400
MY OWN RESEARCH IN OTHER

4687
02:45:05,400 --> 02:45:07,880
CAPACITIES, OTHER CENTERS OF

4688
02:45:07,880 --> 02:45:10,480
EXCELLENCE, BUT, YOU KNOW, I SEE

4689
02:45:10,480 --> 02:45:10,880
AN OPPORTUNITY.

4690
02:45:10,880 --> 02:45:12,640
, RIGHT.

4691
02:45:12,640 --> 02:45:14,840
GREAT, GREAT POINT, NIAID

4692
02:45:14,840 --> 02:45:16,320
ACTUALLY HAS ROBUSTLY SUPPORTED

4693
02:45:16,320 --> 02:45:16,720
THE RO-1.

4694
02:45:16,720 --> 02:45:20,160
THE SEX AND GENDER RO-1 AND

4695
02:45:20,160 --> 02:45:21,040
DR. HUNTER IF YOU WANT TO WEIGH

4696
02:45:21,040 --> 02:45:23,640
IN ON THE CHAT, THAT'S PERFECTLY

4697
02:45:23,640 --> 02:45:24,880
FINE, SEVERAL IN THE FIRST

4698
02:45:24,880 --> 02:45:26,160
ROUND, BUT IT IS AN EMERGING

4699
02:45:26,160 --> 02:45:28,960
AREA AND I THINK THERE'S ROOM

4700
02:45:28,960 --> 02:45:31,880
FOR GROWTH FOR SURE, SO THANK

4701
02:45:31,880 --> 02:45:32,520
FOR THAT.

4702
02:45:32,520 --> 02:45:38,400
OTHER COMMENTS OR OTHER TOPICS

4703
02:45:38,400 --> 02:45:40,600
STILL HAVE TIME BEFORE LUNCH.

4704
02:45:40,600 --> 02:45:46,000
IS THAT YOUR OLD VIRTUAL HAND OR

4705
02:45:46,000 --> 02:45:46,600
NEW VIRTUAL HAND?

4706
02:45:46,600 --> 02:45:47,920
IT'S AN OLD VIRTUAL HAND.

4707
02:45:47,920 --> 02:45:49,440
>>IT'S A NEW VIRTUAL
MACHINE

4708
02:45:49,440 --> 02:45:51,320
YELL HAND, OKAY, GO AHEAD.

4709
02:45:51,320 --> 02:45:52,280
>>REAL QUICKLY SINCE I
TOOK A

4710
02:45:52,280 --> 02:45:53,680
LOT OF TIME TO ANSWER YOUR

4711
02:45:53,680 --> 02:45:57,480
QUESTION, I WOULD JUST ADVISE TO

4712
02:45:57,480 --> 02:45:58,880
CONTINUE TO ALWAYS TRY TO STAY

4713
02:45:58,880 --> 02:46:00,840
AHEAD OF THE CURVE, LIKE YOU'VE

4714
02:46:00,840 --> 02:46:02,560
ALWAYS DONE WHEN THESE STORE

4715
02:46:02,560 --> 02:46:03,320
SCORES FIRST CAME OUT ABOUT

4716
02:46:03,320 --> 02:46:05,320
HAVING TO HAVE A MIXTURE OF

4717
02:46:05,320 --> 02:46:06,600
CLINICAL AND BASIC SCIENCE, THAT

4718
02:46:06,600 --> 02:46:15,240
WAS AHEAD OF THE CURVE AND YOU

4719
02:46:15,240 --> 02:46:25,680
GUYS ARE--YOU HISTORICALLY

4720
02:46:29,400 --> 02:46:30,880
HAVE--WE NEED YOU BEHIND US TO

4721
02:46:30,880 --> 02:46:32,120
DO THAT, THAT'S GREAT.

4722
02:46:32,120 --> 02:46:35,560
AND WE'RE UP FOR THE CHALLENGE.

4723
02:46:35,560 --> 02:46:37,200
THE HEALTH OF WOMEN, I SHOWED

4724
02:46:37,200 --> 02:46:39,600
THAT DATA THAT REDUCTION AND

4725
02:46:39,600 --> 02:46:40,760
LIFE EXPECTANCY DATA, I DIDN'T

4726
02:46:40,760 --> 02:46:41,920
SHOW YOU THE OLD DATA BECAUSE

4727
02:46:41,920 --> 02:46:43,400
I'VE SHOWN IT TO YOU SO MANY

4728
02:46:43,400 --> 02:46:44,640
TIMES, I DON'T WANT TO KEEP

4729
02:46:44,640 --> 02:46:46,520
TAKING IT OUT ON MY TALKS BUT

4730
02:46:46,520 --> 02:46:48,200
IT'S JUST SO DISTURBING, YOU

4731
02:46:48,200 --> 02:46:52,400
KNOW, THE LIFE EXPECTANCY OF THE

4732
02:46:52,400 --> 02:46:54,040
U.S. WOMEN COMPARED TO PEER

4733
02:46:54,040 --> 02:46:55,960
COUNTRIES WAS ALREADY GOING

4734
02:46:55,960 --> 02:46:56,320
DOWN.

4735
02:46:56,320 --> 02:47:01,880
THE LAST 2 YEARS WITH COVID AND

4736
02:47:01,880 --> 02:47:03,080
THEN MATERNAL MORTALITY DATA,

4737
02:47:03,080 --> 02:47:04,400
YOU KNOW, IT JUST SPEAKS TO THE

4738
02:47:04,400 --> 02:47:09,760
NEED FOR DOING THINGS

4739
02:47:09,760 --> 02:47:12,000
DIFFERENTLY, BECAUSE, THERE'S

4740
02:47:12,000 --> 02:47:14,200
INCREDIBLE URGENCY AND THE PAPER

4741
02:47:14,200 --> 02:47:15,720
THAT A COUPLE OF MY COLLEAGUES

4742
02:47:15,720 --> 02:47:17,600
AND I HAVE WROTE IN THE

4743
02:47:17,600 --> 02:47:20,760
BEGINNING OF THE PANDEMIC CALLED

4744
02:47:20,760 --> 02:47:21,800
THE MATERNAL MORTALITY CRISIS

4745
02:47:21,800 --> 02:47:25,160
WITH THE COVID-19 CRISIS, A

4746
02:47:25,160 --> 02:47:27,320
COLLISION OF CRISIS AND IT SEEMS

4747
02:47:27,320 --> 02:47:28,720
THAT THERE'S STILL SO MUCH WORK

4748
02:47:28,720 --> 02:47:32,200
TO BE DONE THERE.

4749
02:47:32,200 --> 02:47:34,320
OTHER THOUGHTS ABOUT OTHER

4750
02:47:34,320 --> 02:47:35,840
TOPICS THAT WE HAVEN'T ADDRESSED

4751
02:47:35,840 --> 02:47:37,240
THUS FAR THAT YOU THINK SHOULD

4752
02:47:37,240 --> 02:47:42,160
BE ON OUR RADAR OR ANY FEEDBACK

4753
02:47:42,160 --> 02:47:44,280
ON ANY OF OUR PROGRAMS, THE NEW

4754
02:47:44,280 --> 02:47:48,440
PROGRAMS OR THOUGHTS, AND

4755
02:47:48,440 --> 02:47:50,120
DR. HUNTEDDER DID AND YOU WILL

4756
02:47:50,120 --> 02:47:52,280
ASSIGNED TO THE SEX AND GENDER

4757
02:47:52,280 --> 02:47:55,440
RO-1 AND THEY CO FUNDED SERL

4758
02:47:55,440 --> 02:47:56,720
APPLICATIONS WITH ORWH FR THE

4759
02:47:56,720 --> 02:47:58,640
LAST ROUND SO THEY'RE COMMENTS

4760
02:47:58,640 --> 02:48:06,600
ON QUESTIONS OR COMMENTS?

4761
02:48:06,600 --> 02:48:07,760
EMPLOY DID.

4762
02:48:07,760 --> 02:48:11,480
>>DR. ROBINSON HAS A
QUESTION.

4763
02:48:11,480 --> 02:48:13,280
>>THANK YOU,.

4764
02:48:13,280 --> 02:48:13,680
>>DR. ROBINSON?

4765
02:48:13,680 --> 02:48:16,840
>>IT'S OKAY, THAIRNG YOU,
I WAS

4766
02:48:16,840 --> 02:48:18,400
TRYING TO THINK IF YOU HAD SEEN

4767
02:48:18,400 --> 02:48:20,000
THIS TOPIC AND MAYBE IF I HAD

4768
02:48:20,000 --> 02:48:23,360
FOR THE BENEFIT OF THE NEW

4769
02:48:23,360 --> 02:48:26,120
MEMBERS, BUT SO MUCH HAS BEEN

4770
02:48:26,120 --> 02:48:29,080
TALKED ABOUT AROUND PERSONALIZED

4771
02:48:29,080 --> 02:48:30,880
HEALTH AND PRECISION MEDICINE

4772
02:48:30,880 --> 02:48:32,080
AND THE INTERSECTION THAT THAT

4773
02:48:32,080 --> 02:48:33,640
HAS WITH A LOT OF THE WORK WE

4774
02:48:33,640 --> 02:48:36,520
DO, I DON'T REMEMBER SEEING THAT

4775
02:48:36,520 --> 02:48:39,640
TOPIC SO DON'T KNOW IF THAT WAS

4776
02:48:39,640 --> 02:48:41,400
SOMETHING FOR THE RADAR FOR THE

4777
02:48:41,400 --> 02:48:43,080
FUTURE, THERE IS A LOT OF

4778
02:48:43,080 --> 02:48:43,920
DEVELOPMENTS THAT WILL BE

4779
02:48:43,920 --> 02:48:45,840
RELEVANT AND TELL BE SUCH AN

4780
02:48:45,840 --> 02:48:46,440
INTERESTING TALK.

4781
02:48:46,440 --> 02:48:48,600
>>THANK YOU SO MUCH
ROCHELLE,

4782
02:48:48,600 --> 02:48:54,640
SO WHEN THE PRECISION MEDICINE

4783
02:48:54,640 --> 02:49:01,280
INITIATIVE FIRST STARTED SOME

4784
02:49:01,280 --> 02:49:02,040
ADMINISTRATIONS AGO, THERE WAS

4785
02:49:02,040 --> 02:49:04,200
INFORMATION ABOUT HOW SEX AND

4786
02:49:04,200 --> 02:49:05,680
GENDER SHOULD BE EMBEDDED INTO

4787
02:49:05,680 --> 02:49:08,120
PRECISION MEDICINE AND THE

4788
02:49:08,120 --> 02:49:10,320
INITIATIVES, SO AS WE MOVED

4789
02:49:10,320 --> 02:49:11,960
FORWARD THROUGH THE YEARS, THAT

4790
02:49:11,960 --> 02:49:15,920
HAS MORPHED INTO ALL OF US

4791
02:49:15,920 --> 02:49:17,760
PROGRAM, AND I'M PRIVILEGED TO

4792
02:49:17,760 --> 02:49:19,200
BE ON THE BRAIN TRUST FOR ALL OF

4793
02:49:19,200 --> 02:49:22,280
US AND SO PART OF THE GROUP OF

4794
02:49:22,280 --> 02:49:24,200
ICO DIRECTORS THAT HAVE THE

4795
02:49:24,200 --> 02:49:25,600
OPPORTUNITY TO COLLABORATE WITH

4796
02:49:25,600 --> 02:49:29,000
THE LEADERSHIP OF ALL OF US TO

4797
02:49:29,000 --> 02:49:31,000
CONTRIBUTE AND SO SEX AND GENDER

4798
02:49:31,000 --> 02:49:32,560
CONSIDERATIONS WE'VE BEEN

4799
02:49:32,560 --> 02:49:34,440
WORKING BEHIND THE SCENES TO GET

4800
02:49:34,440 --> 02:49:38,520
THOSE EMBEDDED INTO WHAT ALL OF

4801
02:49:38,520 --> 02:49:39,880
US HAS BEEN PUTTING FORWARD.

4802
02:49:39,880 --> 02:49:43,160
THE PHRASE THAT I USE IS THAT

4803
02:49:43,160 --> 02:49:45,120
CONSIDERATION OF SEX IS--SHOULD

4804
02:49:45,120 --> 02:49:53,200
BE THE FIRST STEP ON THE ROAD TO

4805
02:49:53,200 --> 02:49:55,240
PRECISION MEDICINE IT'S

4806
02:49:55,240 --> 02:49:56,720
PRETTY--IT'S AN OVERSIGHT TO

4807
02:49:56,720 --> 02:49:58,600
STEP OVER THAT STEP ON YOUR

4808
02:49:58,600 --> 02:50:04,000
JOURNEY TO THE GENETIC LEVEL SO

4809
02:50:04,000 --> 02:50:08,880
WHAT'S HAPPENING IN A PARTICULAR

4810
02:50:08,880 --> 02:50:10,120
GENE OR OTHER MICROLEVEL

4811
02:50:10,120 --> 02:50:14,880
ULTIMATE GOALERATION THAT CAUSES

4812
02:50:14,880 --> 02:50:16,160
DISEASE IS VERY LIKELY, MORE

4813
02:50:16,160 --> 02:50:20,960
LIKELY THAN NOT TO BE INFLUENCED

4814
02:50:20,960 --> 02:50:22,040
BY THE CHROMOSOMAL COMPLEMENT

4815
02:50:22,040 --> 02:50:27,040
SEX AND THE GENDERED EXPERIENCE

4816
02:50:27,040 --> 02:50:28,560
OF THAT INDIVIDUAL WE'RE MISSING

4817
02:50:28,560 --> 02:50:33,040
AN OPPORTUNITY TO BETTER

4818
02:50:33,040 --> 02:50:35,440
UNDERSTAND HOW THESE PRECISION

4819
02:50:35,440 --> 02:50:36,760
MEDICINE TARGETS PLAY OUT AND I

4820
02:50:36,760 --> 02:50:39,160
THINK AWLG THE PRESENTERS--ALL

4821
02:50:39,160 --> 02:50:40,160
THE PRESENTERS TODAY HAVE EACH

4822
02:50:40,160 --> 02:50:42,560
IN THEIR OWN WAY HIGHLIGHTED HOW

4823
02:50:42,560 --> 02:50:45,000
CRITICAL IT IS TO INTEGRATE ALL

4824
02:50:45,000 --> 02:50:47,200
OF THESE INPUTS INTO OUR HEALTH.

4825
02:50:47,200 --> 02:50:49,640
I MEAN RICK'S FIRST COUPLE

4826
02:50:49,640 --> 02:50:51,920
SLIDES, YOU KNOW AND HIS FIRST 5

4827
02:50:51,920 --> 02:50:54,880
MINUTES OF REMARKS WERE JUST, HE

4828
02:50:54,880 --> 02:50:56,120
ELOQUENTLY OUTLINED HOW ALL OF

4829
02:50:56,120 --> 02:50:57,560
THESE PIECES ARE AFFECTING OUR

4830
02:50:57,560 --> 02:51:02,320
HEALTH AT THE SAME TIME AND SO,

4831
02:51:02,320 --> 02:51:03,120
UNIDIMENSIONAL STRATEGIES WHERE

4832
02:51:03,120 --> 02:51:04,840
WE LOOK AT 1 AND THEN WE LOOK AT

4833
02:51:04,840 --> 02:51:06,800
ANOTHER AND WE LOOK OVER TIME

4834
02:51:06,800 --> 02:51:08,040
AND DO META-ANALYSIS, YOU KNOW

4835
02:51:08,040 --> 02:51:12,160
THEY'RE JUST NOT ENOUGH FOR THAT

4836
02:51:12,160 --> 02:51:17,520
INTEGRATION, SO MICHELLE,

4837
02:51:17,520 --> 02:51:18,680
APPLICATIONS ABSOLUTELY.

4838
02:51:18,680 --> 02:51:20,280
AND AND 1 OF THE STRATEGIES TO

4839
02:51:20,280 --> 02:51:21,120
ADVANCE THOSE CONVERSATIONS IN

4840
02:51:21,120 --> 02:51:23,000
THAT CONTEXT IS THROUGH

4841
02:51:23,000 --> 02:51:24,280
INVESTING IN THESE EDUCATIONAL

4842
02:51:24,280 --> 02:51:25,720
MATERIALS AND THE RESOIRSS.

4843
02:51:25,720 --> 02:51:27,840
YOU PROBABLY HAVE NOTICED

4844
02:51:27,840 --> 02:51:29,120
CALIFORNIA BE THERE AT SOMETIME

4845
02:51:29,120 --> 02:51:30,680
THAT EVERY TIME WE MEET, WE HAVE

4846
02:51:30,680 --> 02:51:41,200
A LITTLE BIT OF SOMETHING NEW TO

4847
02:51:48,480 --> 02:51:50,280
TELL YOU ABOUT---SO THE QUESTION

4848
02:51:50,280 --> 02:51:51,680
ABOUT EDUCATING MEDICAL STUDENTS

4849
02:51:51,680 --> 02:51:52,880
AND TRAINEES AND CLIMATE CHANGE

4850
02:51:52,880 --> 02:51:53,720
AND WOMEN'S HEALTH, THAT IS

4851
02:51:53,720 --> 02:51:57,040
SOMETHING WE MIGHT BE ABLE TO

4852
02:51:57,040 --> 02:51:58,520
ADDRESS THROUGH OUR

4853
02:51:58,520 --> 02:51:59,120
INTERPROFESSIONAL EDUCATIONAL

4854
02:51:59,120 --> 02:52:01,120
MATERIALS SO THAT WILL BE OTHER

4855
02:52:01,120 --> 02:52:04,360
THOUGHTS ON THAT? 

4856
02:52:04,360 --> 02:52:04,960
FROM ANYONE?

4857
02:52:04,960 --> 02:52:08,600
AND RICK ALSO ADDED THE

4858
02:52:08,600 --> 02:52:13,280
PRECISION ENVIRONMENTAL HEALTH

4859
02:52:13,280 --> 02:52:14,360
ACTIVITIES AND NIEHS IS WORKING

4860
02:52:14,360 --> 02:52:17,240
WITH THE ALL OF US LEADERSHIP TO

4861
02:52:17,240 --> 02:52:17,840
BRING ENVIRONMENTAL EXPOSURES

4862
02:52:17,840 --> 02:52:19,400
INTO THE ALL OF US FRAMEWORK,

4863
02:52:19,400 --> 02:52:21,400
THANK YOU SO MUCH RICK AND THAT

4864
02:52:21,400 --> 02:52:22,840
WILL INCLUDE IMPACTS OF

4865
02:52:22,840 --> 02:52:24,280
ENVIRONMENTAL EXPOSURES ON

4866
02:52:24,280 --> 02:52:27,320
WOMEN'S HEALTH INCLUDING GENETIC

4867
02:52:27,320 --> 02:52:27,680
BACKGROUND.

4868
02:52:27,680 --> 02:52:29,000
SO YOU'RE ABSOLUTELY RIGHT AND I

4869
02:52:29,000 --> 02:52:30,920
APPRECIATE YOU BRINGING IT BACK

4870
02:52:30,920 --> 02:52:33,840
UP SO IT COULD BE TOP OF MIND AS

4871
02:52:33,840 --> 02:52:35,320
WE THINK GOING FORWARD

4872
02:52:35,320 --> 02:52:36,600
ESPECIALLY GOING FORWARD IN HOW

4873
02:52:36,600 --> 02:52:38,640
WE FORMULATE THE NEXT NIH WIDE

4874
02:52:38,640 --> 02:52:41,280
STRATEGIC PLAN FOR WOMEN'S

4875
02:52:41,280 --> 02:52:49,000
HEALTH. 

4876
02:52:49,000 --> 02:52:50,400
OTHER COMMENTS?

4877
02:52:50,400 --> 02:52:57,040
>>I HAVE A QUICK COMMENT.

4878
02:52:57,040 --> 02:52:58,760
AND IT'S--YOU KNOW WHEN WE

4879
02:52:58,760 --> 02:53:01,160
STARTED THE Q&A, YOU
MENTIONED

4880
02:53:01,160 --> 02:53:04,120
WE ARE LOOKING FOR ADVICE OR

4881
02:53:04,120 --> 02:53:06,760
COMMENTS ON WHAT ORWH POSTURE

4882
02:53:06,760 --> 02:53:07,880
SHOULD TAKE OR FOCUS SHOULD BE

4883
02:53:07,880 --> 02:53:09,800
ON AND HAVING BEEN ON THIS

4884
02:53:09,800 --> 02:53:10,640
AMAZING ADVISORY COMMITTEE FOR

4885
02:53:10,640 --> 02:53:11,960
SEVERAL YEARS NOW, I REMEMBER

4886
02:53:11,960 --> 02:53:17,360
THINKING IN THE BEGINNING, THAT

4887
02:53:17,360 --> 02:53:21,600
WAS WEARY TO GET TOO DILUTE AND

4888
02:53:21,600 --> 02:53:22,800
SO WHEN JANINE, YOU WERE

4889
02:53:22,800 --> 02:53:23,840
THINKING ABOUT WE SHOULD ALSO

4890
02:53:23,840 --> 02:53:24,840
THINK ABOUT WOMEN AS SCIENTISTS

4891
02:53:24,840 --> 02:53:26,600
AND I CAME INTO THIS WITH THE

4892
02:53:26,600 --> 02:53:29,600
SEX AND GENDER, YOU KNOW HELMET

4893
02:53:29,600 --> 02:53:31,880
ON AND THEN, YOU KNOW EVERY

4894
02:53:31,880 --> 02:53:33,840
TIME, I'M SEEING ALL OF

4895
02:53:33,840 --> 02:53:37,160
THESE--YOU KNOW ALL THESE

4896
02:53:37,160 --> 02:53:38,520
PRESENTATIONS TODAY IT'S REALLY,

4897
02:53:38,520 --> 02:53:39,720
REALLY AWESOME THAT IT'S

4898
02:53:39,720 --> 02:53:41,280
BECOMING SO INTEGRATED AND WE

4899
02:53:41,280 --> 02:53:45,120
ARE EMBRACING THE COMPLEXITY OF

4900
02:53:45,120 --> 02:53:47,800
IT AND SO, IT'S MORE OF A

4901
02:53:47,800 --> 02:53:50,360
COMMENT THAT I'M SO EXCITED TO

4902
02:53:50,360 --> 02:53:53,160
SEE THAT ALL OF THESE

4903
02:53:53,160 --> 02:53:55,120
PRESENTATIONS AND OTHER ICOs

4904
02:53:55,120 --> 02:53:57,400
ARE MICKING THIS PART OF WHAT

4905
02:53:57,400 --> 02:53:58,880
THEY'RE DOING AS WELL.

4906
02:53:58,880 --> 02:54:04,880
SO I THINK, WE SHOULD CONTINUE

4907
02:54:04,880 --> 02:54:08,680
TO PROMOTE THAT AS AS THE ORWH'S

4908
02:54:08,680 --> 02:54:09,080
STANDPOINT.

4909
02:54:09,080 --> 02:54:10,880
I'M SNOT SURE ABOUT

4910
02:54:10,880 --> 02:54:12,920
FOCUSING--I'M NOT SURE ABOUT

4911
02:54:12,920 --> 02:54:14,120
FOCUSING ANYTHING ANYMORE WHEN

4912
02:54:14,120 --> 02:54:15,400
WE FINALLY HAVE EVERYBODY

4913
02:54:15,400 --> 02:54:17,000
LOOKINGA THE IT, AT THEIR

4914
02:54:17,000 --> 02:54:18,080
SCIENCE THROUGH THIS LENS.

4915
02:54:18,080 --> 02:54:21,000
SO I JUST BRING THAT UP FOR

4916
02:54:21,000 --> 02:54:21,320
DISCUSSION.

4917
02:54:21,320 --> 02:54:22,640
THANKS ALLYSON AND I THINK THAT,

4918
02:54:22,640 --> 02:54:24,720
YOU KNOW THAT MAY PLAY OUT A BIT

4919
02:54:24,720 --> 02:54:27,480
AS WE MOVE FORWARD, WITH THE

4920
02:54:27,480 --> 02:54:29,960
NEXT BIENNIAL REPORT, I AM

4921
02:54:29,960 --> 02:54:31,000
ALWAYS, SO DELIGHTED AND I

4922
02:54:31,000 --> 02:54:32,760
LEARNED SO MUCH FROM THE

4923
02:54:32,760 --> 02:54:43,240
INSTITUTES WHEN THEY SUBMIT

4924
02:54:45,120 --> 02:54:46,680
THEIR REPORTS ON WOMEN'S HEALTH.

4925
02:54:46,680 --> 02:54:47,920
A BIT CONCERNED THAT WE WILL

4926
02:54:47,920 --> 02:54:50,040
ADAPT TO THAT FORM AT AS WE MOVE

4927
02:54:50,040 --> 02:54:51,600
FORWARD BUT YOU KNOW, IT'S

4928
02:54:51,600 --> 02:54:53,800
VARIABLE IN TERMS OF HOW EACH IC

4929
02:54:53,800 --> 02:54:54,960
ADDRESSING THIS, BECAUSE THE

4930
02:54:54,960 --> 02:54:59,480
SCIENCE THAT THEY'RE SUPPORTING

4931
02:54:59,480 --> 02:55:01,400
IS VARIABLE, THE PRYERITYS ARE

4932
02:55:01,400 --> 02:55:03,000
VARIABLE, THE INSTITUTE

4933
02:55:03,000 --> 02:55:04,040
DIRECTORS HAVE THEIR OWN

4934
02:55:04,040 --> 02:55:05,240
APPROACHES TO THEIR INSTITUTES

4935
02:55:05,240 --> 02:55:06,560
AND CENTERS ABOUT YOU I HAVE TO

4936
02:55:06,560 --> 02:55:08,280
SAY, IT'S A PLEASURE TO WORK

4937
02:55:08,280 --> 02:55:11,280
WITH EACH AND EVERY 1 OF THEM TO

4938
02:55:11,280 --> 02:55:13,120
BE ABLE TO ADVANCE WOMEN'S

4939
02:55:13,120 --> 02:55:14,680
HEALTH RESEARCH AND THERE ARE

4940
02:55:14,680 --> 02:55:16,560
MANY NEW INSTITUTE AND CENTER

4941
02:55:16,560 --> 02:55:18,000
DIRECTORS, SO EACH TIME WE MEET,

4942
02:55:18,000 --> 02:55:20,680
I SHARE THE PHOTOS OF THE NEWEST

4943
02:55:20,680 --> 02:55:22,800
THAT HAVE COME, AND SO WE'RE

4944
02:55:22,800 --> 02:55:26,360
ESPECIALLY EXCITED ABOUT THE NEW

4945
02:55:26,360 --> 02:55:28,160
NCI DIRECTOR, WHO IS--HAS A

4946
02:55:28,160 --> 02:55:30,560
RECORD OF BEING CONCERNED ABOUT

4947
02:55:30,560 --> 02:55:34,800
WOMEN'S SURGEONS AS WELL AS

4948
02:55:34,800 --> 02:55:35,960
WOMEN'S CANCERS AND HEALTH

4949
02:55:35,960 --> 02:55:37,160
DISPARITIES AND MANY OTHER

4950
02:55:37,160 --> 02:55:42,240
ASPECTS THAT ARE  IMPORTANT TO

4951
02:55:42,240 --> 02:55:43,560
ORWH AND PART OF WHAT I GET TO

4952
02:55:43,560 --> 02:55:45,080
DO AND I FEEL IT'S A REAL

4953
02:55:45,080 --> 02:55:46,520
PRIVILEGE TO BE ABLE TO

4954
02:55:46,520 --> 02:55:47,640
HIGHLIGHT THE AMAZING WORK AT

4955
02:55:47,640 --> 02:55:50,480
THE INSTITUTES AND CENTERS ARE

4956
02:55:50,480 --> 02:55:52,520
DOING AS I'M OUTSPEAKING.

4957
02:55:52,520 --> 02:55:56,080
SO WE WILL CERTAINLY CONTINUE TO

4958
02:55:56,080 --> 02:55:59,880
DO THAT AND I THINK WITH THAT WE

4959
02:55:59,880 --> 02:56:01,600
CAN GO TO DR. SHARPS, WE'RE

4960
02:56:01,600 --> 02:56:06,360
DELIGHTED TO HAVE YOU DR. SHARPS

4961
02:56:06,360 --> 02:56:08,600
WITH US TODAY.

4962
02:56:08,600 --> 02:56:09,040
>>GOOD MORNING.

4963
02:56:09,040 --> 02:56:12,320
VERY PLEASED TO BE HERE AND THIS

4964
02:56:12,320 --> 02:56:14,200
IS MY FIRST MEETING AND WHILE

4965
02:56:14,200 --> 02:56:16,960
THERE CERTAINLY IS MORE RESEARCH

4966
02:56:16,960 --> 02:56:18,480
TO DO, IT'S IMPRESSIVE HOW MUCH

4967
02:56:18,480 --> 02:56:22,120
WE HAVE ALREADY LEARNED AND I

4968
02:56:22,120 --> 02:56:22,760
PARTICULARLY ENJOYED THE

4969
02:56:22,760 --> 02:56:24,840
CONVERSATION IN THINKING ABOUT

4970
02:56:24,840 --> 02:56:26,120
COMMUNICATION AND GETTING IT TO

4971
02:56:26,120 --> 02:56:30,920
POLICY MAKERS AND CLINICIANS BUT

4972
02:56:30,920 --> 02:56:33,280
PART OF DR. WOYCHIK'S

4973
02:56:33,280 --> 02:56:35,160
PRESENTATION TALKED ABOUT THE

4974
02:56:35,160 --> 02:56:37,360
WOMEN'S HEALTH AWARENESS CENTER

4975
02:56:37,360 --> 02:56:38,000
AND PROGRAM.

4976
02:56:38,000 --> 02:56:40,280
IT SOUNDS LIKE A COMMUNITY

4977
02:56:40,280 --> 02:56:41,400
OUTREACH AND ENGAGEMENT AND

4978
02:56:41,400 --> 02:56:42,960
CAPACITY BUILDING AND SO I THINK

4979
02:56:42,960 --> 02:56:45,360
THAT THAT'S AN IMPORTANT

4980
02:56:45,360 --> 02:56:48,520
STRATEGY TO THINK ABOUT.

4981
02:56:48,520 --> 02:56:49,840
WE'RE LEARNING A LOT OF THINGS

4982
02:56:49,840 --> 02:56:51,240
THAT INDIVIDUALS AND COMMUNITIES

4983
02:56:51,240 --> 02:56:53,440
AND WE KNOW ANOTHER BIG ROLE OF

4984
02:56:53,440 --> 02:56:55,280
WOMEN, I MEAN THEY'RE THE GATE

4985
02:56:55,280 --> 02:56:57,680
KEEPERS FOR FAMILY HEALTH,

4986
02:56:57,680 --> 02:56:58,400
COMMUNITY HEALTH, OFTEN SCHOOL

4987
02:56:58,400 --> 02:57:02,200
HEALTH AND SO, IF THERE'S A WAY

4988
02:57:02,200 --> 02:57:03,920
TO DEVELOP MECHANISMS THAT

4989
02:57:03,920 --> 02:57:06,200
SUPPORT NOT ONLY SCIENTISTS BUT

4990
02:57:06,200 --> 02:57:09,760
ALSO REALLY HAVING MEANINGFUL

4991
02:57:09,760 --> 02:57:11,160
AND EFFECTIVE ENGAGEMENT WITH

4992
02:57:11,160 --> 02:57:13,880
COMMUNITIES AND BUILDING THAT

4993
02:57:13,880 --> 02:57:15,600
CAPACITY TO GET THE INFORMATION

4994
02:57:15,600 --> 02:57:18,240
OUT AT THAT LEVEL, TOO, I THINK

4995
02:57:18,240 --> 02:57:19,520
IT'S SOMETHING WE COULD THINK

4996
02:57:19,520 --> 02:57:21,840
ABOUT OR IS IMPORTANT TO THINK

4997
02:57:21,840 --> 02:57:22,040
ABOUT.

4998
02:57:22,040 --> 02:57:22,360
THANK YOU.

4999
02:57:22,360 --> 02:57:25,600
>>THANK YOU SO MUCH DR.
SHARPS,

5000
02:57:25,600 --> 02:57:26,760
ABSOLUTELY AGREE 100% WITH YOU.

5001
02:57:26,760 --> 02:57:32,560
AND WE HAVE SUPPORTED DR. P A

5002
02:57:32,560 --> 02:57:33,840
CKEMHAM'S OUTREACH FOR SEVERAL

5003
02:57:33,840 --> 02:57:36,000
YEARS AND ACTUALLY I SPOKE AT

5004
02:57:36,000 --> 02:57:37,680
HER PROGRAM MOST RECENTLY AND

5005
02:57:37,680 --> 02:57:40,480
SHE HAS INCREDIBLE LEVEL OF

5006
02:57:40,480 --> 02:57:43,080
ENGAGEMENT IN NORTH CAROLINA AND

5007
02:57:43,080 --> 02:57:46,600
PARTNERSHIPS WITH HBCUs AS

5008
02:57:46,600 --> 02:57:49,640
WELL AS FRATERNITIES AND

5009
02:57:49,640 --> 02:57:51,760
SORORITYS IN THE AREA SO SHE'S

5010
02:57:51,760 --> 02:57:53,160
HAS A MACHINE, A WELL OILED

5011
02:57:53,160 --> 02:57:55,640
MACHINE THERE THAT WAS LEVERAGED

5012
02:57:55,640 --> 02:57:57,360
AND GOT EVEN MORE ACTIVATED WITH

5013
02:57:57,360 --> 02:57:58,680
THE PANDEMIC SO THAT'S 1 WAY

5014
02:57:58,680 --> 02:58:00,080
THAT WE'RE DOING THAT.

5015
02:58:00,080 --> 02:58:02,160
OF COURSE, THERE'S ROOM FOR THAT

5016
02:58:02,160 --> 02:58:06,080
IN SO MANY PLACES AND SPACES AS

5017
02:58:06,080 --> 02:58:08,400
WELL.

5018
02:58:08,400 --> 02:58:10,120
>>I WAS SO EXCITED TO
SHARE 

5019
02:58:10,120 --> 02:58:16,360
WITH YOU THE INFORMATION ABOUT 

5020
02:58:16,360 --> 02:58:26,840
THE COMPASS INITIATIVES IS IS 

5021
02:58:29,040 --> 02:58:30,120
WHERE THE COMMUNITY ORGANIZATION

5022
02:58:30,120 --> 02:58:30,560
IS THE LEAD.

5023
02:58:30,560 --> 02:58:32,360
THEY SUBMIT THE APPLICATION.

5024
02:58:32,360 --> 02:58:35,200
THE FUNDING GOES DIRECTLY TO THE

5025
02:58:35,200 --> 02:58:35,880
COMMUNITY ORGANIZATION.

5026
02:58:35,880 --> 02:58:38,720
IT'S AROUND STRUCTURAL 

5027
02:58:38,720 --> 02:58:40,840
INTERVENTIONS WHICH ARE SO 

5028
02:58:40,840 --> 02:58:44,640
CRITICAL TO HEALTH AS WE'VE 

5029
02:58:44,640 --> 02:58:46,280
LEARNED.

5030
02:58:46,280 --> 02:58:48,360
SO I THINK THAT THERE'S 

5031
02:58:48,360 --> 02:58:49,320
DIFFERENT ASPECTS OF COMMUNITY 

5032
02:58:49,320 --> 02:58:51,600
HEALTH AND HOW TO ENGAGE AND 

5033
02:58:51,600 --> 02:58:54,080
WHAT IMPLEMENTATION SCIENCE 

5034
02:58:54,080 --> 02:58:57,600
LOOKS LIKE AND WHAT COMMUNITY 

5035
02:58:57,600 --> 02:58:58,560
BASED PARTICIPATORY RESEARCH 

5036
02:58:58,560 --> 02:59:04,160
LOOKS LIKE BUT THE PRINCIPLES OF

5037
02:59:04,160 --> 02:59:05,320
INVOLVING COMMUNITY AND TAKING 

5038
02:59:05,320 --> 02:59:07,480
THAT AS SERIOUSLY AS ANY OTHER 

5039
02:59:07,480 --> 02:59:08,840
PARTNER SO WE ARE RIGOROUS ABOUT

5040
02:59:08,840 --> 02:59:13,840
HOW WE DO THAT.

5041
02:59:13,840 --> 02:59:19,920
THAT WE CO-CREATE PROGRAMS 

5042
02:59:19,920 --> 02:59:25,760
RATHER THAN AN ACADEMIC CENTER 

5043
02:59:25,760 --> 02:59:26,880
AND THE COMPASS ORGANIZATION 

5044
02:59:26,880 --> 02:59:27,880
WILL REACH OUT TO US.

5045
02:59:27,880 --> 02:59:30,200
AND WITH THAT OUR IMPROVED 

5046
02:59:30,200 --> 02:59:31,840
COMMITTEE CHALLENGE IS VERY MUCH

5047
02:59:31,840 --> 02:59:32,320
LIKE THAT.

5048
02:59:32,320 --> 02:59:36,200
WE'LL HOPE TO BE ABLE TO 

5049
02:59:36,200 --> 02:59:36,840
ANNOUNCE INFORMATION ABOUT THAT 

5050
02:59:36,840 --> 02:59:38,360
SOON COMMUNITY ORGANIZATIONS 

5051
02:59:38,360 --> 02:59:39,600
APPLIED FOR WAYS TO ADDRESS 

5052
02:59:39,600 --> 02:59:41,000
MATERNAL MORTALITY THROUGH THE 

5053
02:59:41,000 --> 02:59:41,920
IMPROVED COMMUNITY CHALLENGE.

5054
02:59:41,920 --> 02:59:43,200
BUT WE'RE NOW ONE MINUTE OVER.

5055
02:59:43,200 --> 02:59:44,880
I WANT TO BE RESPECTFUL OF TIME 

5056
02:59:44,880 --> 02:59:46,920
AND WE NEED TO DO A PHOTO AND 

5057
02:59:46,920 --> 02:59:47,960
YOU ALL NEED TO HAVE SOME LUNCH 

5058
02:59:47,960 --> 02:59:51,760
SO LET ME TURN IT OVER TO 

5059
02:59:51,760 --> 02:59:52,080
DR. NOURSI.

5060
02:59:52,080 --> 02:59:54,560
>>THANK YOU, DR. CLAYTON.

5061
02:59:54,560 --> 02:59:56,880
THANK YOU EVERYONE FOR THIS 

5062
02:59:56,880 --> 02:59:57,960
GREAT MORNING WITH GREAT 

5063
02:59:57,960 --> 02:59:58,400
DISCUSSION.

5064
02:59:58,400 --> 03:00:02,800
SO YES, WE WILL BE BACK AT 1:00.

5065
03:00:02,800 --> 03:00:07,200
PLEASE JOIN US AT 1:00 FOR A 

5066
03:00:07,200 --> 03:00:08,640
STIMULATING PANEL ON 

5067
03:00:08,640 --> 03:00:10,240
ENVIRONMENTAL HEALTH AS WELL.

5068
03:00:10,240 --> 03:00:11,680
WE WILL HAVE ALSO UPDATES TO 

5069
03:00:11,680 --> 03:00:16,120
GIVE YOU ALL ON WHERE WE ARE 

5070
03:00:16,120 --> 03:00:18,120
WITH OUR NEXT STRATEGIC PLAN AND

5071
03:00:18,120 --> 03:00:19,640
WE'LL HAVE ONE CONCEPT CLEARANCE

5072
03:00:19,640 --> 03:00:21,560
AND A DEMONSTRATION OF THE 

5073
03:00:21,560 --> 03:00:21,800
MODULE.

5074
03:00:21,800 --> 03:00:25,200
BUT BEFORE YOU LOG OFF I ASK 

5075
03:00:25,200 --> 03:00:26,840
THAT ALL COMMITTEE MEMBERS IF 

5076
03:00:26,840 --> 03:00:29,200
YOU CAN STAY ON PUT YOUR CAMERA 

5077
03:00:29,200 --> 03:00:32,040
ON SO WE CAN TAKE A GROUP PHOTO.

5078
03:00:32,040 --> 03:00:35,440
AND THEN WE'LL SEE I AFTER THAT 

5079
03:00:35,440 --> 03:00:38,080
AT 1:00.

5080
03:00:38,080 --> 03:00:40,360
SO SARA IS OUR VIRTUAL 

5081
03:00:40,360 --> 03:00:40,680
PHOTOGRAPHER.

5082
03:00:40,680 --> 03:00:43,880
>>THAT TOO.

5083
03:00:43,880 --> 03:00:44,320
SHE'S GOT MANY HATS.

5084
03:00:44,320 --> 03:00:47,440
SO IF YOU CAN KEEP YOUR CAMERA 

5085
03:00:47,440 --> 03:00:52,080
ON FOR ALL MEMBERS AND SARA TELL

5086
03:00:52,080 --> 03:00:56,320
ME OR DR. ANDERSON -- I DON'T 

5087
03:00:56,320 --> 03:00:58,360
SEE YOUR PICTURE.

5088
03:00:58,360 --> 03:00:59,960
>>THERE SHE IS.

5089
03:00:59,960 --> 03:01:02,160
GREAT TO SEE YOU.

5090
03:01:02,160 --> 03:01:02,480
OKIE DOKE.

5091
03:01:02,480 --> 03:01:04,800
I THINK WE HAVE EVERYONE, SARA, 

5092
03:01:04,800 --> 03:01:05,040
RIGHT?

5093
03:01:05,040 --> 03:01:10,960
>>IF EVERYONE CAN SMILE
FOR ME.

5094
03:01:10,960 --> 03:01:17,200
THREE, TWO, ONE.

5095
03:01:17,200 --> 03:01:17,440
GOTCHA.

5096
03:01:17,440 --> 03:01:19,120
>>ENJOY YOUR LUNCH WE'LL
HAVE A

5097
03:01:19,120 --> 03:01:20,880
SLIDE ROTATOR DURING LUNCH IF 

5098
03:01:20,880 --> 03:01:23,000
YOU TAKE A LOOK AT IT DURING 

5099
03:01:23,000 --> 03:01:23,960
YOUR BREAK THAT WOULD BE GREAT 

5100
03:01:23,960 --> 03:01:25,160
BUT WE'LL SEE YOU ALL BACK AT 

5101
03:01:25,160 --> 03:01:25,360
1:00.

5102
03:01:25,360 --> 03:01:33,160
THANK YOU VERY MUCH.

5103
03:01:33,160 --> 03:01:38,320
IT'S 1:00 AND I'D LIKE TO 

5104
03:01:38,320 --> 03:01:39,920
WELCOME YOU BACK AND HOPE YOU 

5105
03:01:39,920 --> 03:01:40,920
ENJOYED YOUR LUNCH AND THE PHOTO

5106
03:01:40,920 --> 03:01:41,480
SLIDE SHOW.

5107
03:01:41,480 --> 03:01:44,040
I'D LIKE TO CALL INTO THE 

5108
03:01:44,040 --> 03:01:47,640
MEETING THIS AFTERNOON AND HAND 

5109
03:01:47,640 --> 03:01:54,760
IT OFF TO DR. REGINE DOUTHARD TO

5110
03:01:54,760 --> 03:01:59,960
INTRODUCE OUR NEXT SPEAKER.

5111
03:01:59,960 --> 03:02:01,200
>>THANK YOU VERY MUCH.

5112
03:02:01,200 --> 03:02:04,600
GOOD AFTERNOON, EVERYONE.

5113
03:02:04,600 --> 03:02:07,520
MY NAME IS REGINE DOUTHARD AND 

5114
03:02:07,520 --> 03:02:12,600
IT'S MY PLEASURE TO INTRODUCE 

5115
03:02:12,600 --> 03:02:15,160
DR. KRISTEN UPSON THE CHAIR OF 

5116
03:02:15,160 --> 03:02:19,920
OUR PANEL AND THE PANEL IS 

5117
03:02:19,920 --> 03:02:21,280
EPIDEMIOLOGIC CONTRIBUTION TO 

5118
03:02:21,280 --> 03:02:22,800
UNDERSTANDING THE ENVIRONMENTAL 

5119
03:02:22,800 --> 03:02:24,440
IMPACT ON WOMEN'S HEALTH.

5120
03:02:24,440 --> 03:02:27,480
SHE'S AN ASSISTANT PROFESSOR IN 

5121
03:02:27,480 --> 03:02:28,560
THE DEPARTMENT OF EPIDEMIOLOGY 

5122
03:02:28,560 --> 03:02:30,200
AND BIO STATISTICS IN THE 

5123
03:02:30,200 --> 03:02:33,000
COLLEGE OF HUMAN MEDICINE AT 

5124
03:02:33,000 --> 03:02:35,880
MICHIGAN STATE UNIVERSITY.

5125
03:02:35,880 --> 03:02:40,360
SHE IS AN EPIDEMIOLOGIST WHO'S 

5126
03:02:40,360 --> 03:02:41,200
RESEARCH INTERSECTS 

5127
03:02:41,200 --> 03:02:43,600
ENVIRONMENTAL HEALTH WITH HER 

5128
03:02:43,600 --> 03:02:45,400
RESEARCH PROGRAM FOR 

5129
03:02:45,400 --> 03:02:49,200
ENVIRONMENTAL STRUCTURES FOR 

5130
03:02:49,200 --> 03:02:50,800
ENDOMETRIOSIS AND OTHER 

5131
03:02:50,800 --> 03:02:51,080
DISEASES.

5132
03:02:51,080 --> 03:02:54,240
DR. UPSON RECEIVED HER Ph.D. IN 

5133
03:02:54,240 --> 03:02:57,240
EPIDEMIOLOGY FROM THE UNIVERSITY

5134
03:02:57,240 --> 03:03:00,040
OF WASHINGTON AND POSTDOCTORAL 

5135
03:03:00,040 --> 03:03:02,080
TRAINING AT THE NIH NATIONAL 

5136
03:03:02,080 --> 03:03:02,640
INSTITUTE OF ENVIRONMENTAL 

5137
03:03:02,640 --> 03:03:03,040
HEALTH SCIENCES.

5138
03:03:03,040 --> 03:03:06,640
SHE IS CURRENTLY THE PRINCIPAL 

5139
03:03:06,640 --> 03:03:08,640
INVESTIGATOR OF AN NIH R00 FROM 

5140
03:03:08,640 --> 03:03:11,800
THE STUDY FROM THE NATIONAL 

5141
03:03:11,800 --> 03:03:13,280
INSTITUTE OF NURSING RESEARCH TO

5142
03:03:13,280 --> 03:03:21,960
INVESTIGATE TOXIC METALS AND 

5143
03:03:21,960 --> 03:03:24,600
UTERINE FIBROID RISK AND WOMEN 

5144
03:03:24,600 --> 03:03:26,680
THAT MAY INCREASE TOXIC METAL 

5145
03:03:26,680 --> 03:03:28,720
BODY BURDEN.

5146
03:03:28,720 --> 03:03:33,000
DR. UPSON SERVED AS AN ASSOCIATE

5147
03:03:33,000 --> 03:03:35,560
EDITOR TO THE HUMAN REPRODUCTION

5148
03:03:35,560 --> 03:03:39,200
AND RECEIVED HER EARLY CAREER 

5149
03:03:39,200 --> 03:03:42,000
RESEARCH EXCELLENCE AWARD FROM 

5150
03:03:42,000 --> 03:03:42,920
THE MICHIGAN STATE UNIVERSITY 

5151
03:03:42,920 --> 03:03:46,840
COLLEGE OF HUMAN MEDICINE.

5152
03:03:46,840 --> 03:03:48,600
DR. UPSON, WE ARE DELIGHTED TO 

5153
03:03:48,600 --> 03:03:49,800
HAVE YOU HERE WITH US THIS 

5154
03:03:49,800 --> 03:03:50,360
AFTERNOON AND THE FLOOR IS 

5155
03:03:50,360 --> 03:03:53,680
YOURS.

5156
03:03:53,680 --> 03:03:55,920
>>THANK YOU VERY MUCH 

5157
03:03:55,920 --> 03:04:01,800
DR. DOUTHARD FOR THE 

5158
03:04:01,800 --> 03:04:02,120
INTRODUCTION.

5159
03:04:02,120 --> 03:04:05,720
I APPRECIATE THIS OPPORTUNITY TO

5160
03:04:05,720 --> 03:04:07,640
CHAIR THIS PANEL AND I'LL GO 

5161
03:04:07,640 --> 03:04:08,680
AHEAD AND SHARE MY SLIDES.

5162
03:04:08,680 --> 03:04:11,240
I REALLY APPRECIATE THIS 

5163
03:04:11,240 --> 03:04:13,080
OPPORTUNITY TO CHAIR THIS PANEL 

5164
03:04:13,080 --> 03:04:14,480
ON THE EPIDEMIOLOGIC 

5165
03:04:14,480 --> 03:04:16,600
CONTRIBUTION TO UNDERSTANDING 

5166
03:04:16,600 --> 03:04:18,280
ENVIRONMENTAL IMPACT ON WOMEN'S 

5167
03:04:18,280 --> 03:04:18,600
HEALTH.

5168
03:04:18,600 --> 03:04:22,040
ON THIS PANEL I'M JOINED BY 

5169
03:04:22,040 --> 03:04:25,200
DR. QUAKER HARMON AND DALE 

5170
03:04:25,200 --> 03:04:27,160
SANDLER FOCUS ON THE GYNECOLOGIC

5171
03:04:27,160 --> 03:04:30,680
CONDITIONS OF ENDOMETRIOSIS AND 

5172
03:04:30,680 --> 03:04:32,840
UTERINE FIBOIDS AND WOMEN'S 

5173
03:04:32,840 --> 03:04:33,440
HEALTH IN GENERAL.

5174
03:04:33,440 --> 03:04:34,640
EACH SPEAKER WILL PRESENT FOR 20

5175
03:04:34,640 --> 03:04:37,400
MINUTES FOLLOWED BY FIVE MINUTES

5176
03:04:37,400 --> 03:04:39,200
OF Q&A AFTER EACH TALK.

5177
03:04:39,200 --> 03:04:41,800
AFTER THE THREE TALKS, WE'LL 

5178
03:04:41,800 --> 03:04:43,440
SYNTHESIZE THEMES FROM THE TALKS

5179
03:04:43,440 --> 03:04:48,600
AND HAVE ALLOWED 15 MINUTES FOR 

5180
03:04:48,600 --> 03:04:53,680
A Q&A SESSION TO DISCUSS THE

5181
03:04:53,680 --> 03:04:56,520
GAPS AND IT WILL BE MODERATED BY

5182
03:04:56,520 --> 03:05:06,680
DR. REGINE DOUTHARD.

5183
03:05:06,680 --> 03:05:11,320
IN THE CASE OF ENDOMETRIOSIS AND

5184
03:05:11,320 --> 03:05:17,880
UTERINE FIBROID LANGUAGE IS 

5185
03:05:17,880 --> 03:05:20,040
CIS-WOMAN RELATED TERMINOLOGY 

5186
03:05:20,040 --> 03:05:28,600
BUT WOMEN NOT A UTERUS CAN HAVE 

5187
03:05:28,600 --> 03:05:30,200
THESE CONDITION AND I'LL SHARE 

5188
03:05:30,200 --> 03:05:32,600
THE RESULTS FROM OUR STUDY.

5189
03:05:32,600 --> 03:05:33,680
ENDOMETRIOSIS IS CHARACTERIZED 

5190
03:05:33,680 --> 03:05:36,160
BY TISSUE RESEMBLING THE UTERINE

5191
03:05:36,160 --> 03:05:38,760
LINING APPEARING OUTSIDE THE 

5192
03:05:38,760 --> 03:05:40,800
UTERUS USUALLY IN THE PELVIC 

5193
03:05:40,800 --> 03:05:41,040
CAVITY.

5194
03:05:41,040 --> 03:05:47,680
WE CAN SEE LESIONS OVER THE 

5195
03:05:47,680 --> 03:05:52,040
OVARIES AND DEEP LESIONS WHICH 

5196
03:05:52,040 --> 03:05:54,800
CAN REPRESENT AS RECTAL VAGINAL 

5197
03:05:54,800 --> 03:05:56,320
LESIONS AS WELL AS ADHESIONS.

5198
03:05:56,320 --> 03:06:00,360
INDIVIDUALS WITH ENDOMETRIOSIS 

5199
03:06:00,360 --> 03:06:01,640
CAN REPORT CONSIDERABLE PAIN 

5200
03:06:01,640 --> 03:06:03,000
SYMPTOMS INCLUDING CHRONIC 

5201
03:06:03,000 --> 03:06:07,440
PELVIC PAIN, PAINFUL MENSTRUAL 

5202
03:06:07,440 --> 03:06:09,160
PERIODS, PAINFUL BIO MOVEMENTS 

5203
03:06:09,160 --> 03:06:18,360
AND URINATION AND THIS CAN 

5204
03:06:18,360 --> 03:06:20,240
INTERFERE WITH DAILY ACTIVITY, 

5205
03:06:20,240 --> 03:06:21,600
WORK PRODUCTIVITY AND SCHOOL 

5206
03:06:21,600 --> 03:06:23,520
PERFORMANCE AND PERSONAL 

5207
03:06:23,520 --> 03:06:23,920
RELATIONSHIPS.

5208
03:06:23,920 --> 03:06:26,240
DESPITE THIS, IT'S NOT WELL 

5209
03:06:26,240 --> 03:06:27,480
UNDERSTOOD WHY IT DEVELOPS IN 

5210
03:06:27,480 --> 03:06:29,280
SOME INDIVIDUALS BUT NOT OTHERS.

5211
03:06:29,280 --> 03:06:32,040
THE MOST WIDELY ACCEPTED THEORY 

5212
03:06:32,040 --> 03:06:36,320
OF ENDOMETRIOSIS PATHOGENESIS IS

5213
03:06:36,320 --> 03:06:40,600
LINING OF THE UTERUS SHED WITH 

5214
03:06:40,600 --> 03:06:45,600
EACH MENSES LEAD TO THE 

5215
03:06:45,600 --> 03:06:47,280
IMPLANTATION OF TISSUE AND 

5216
03:06:47,280 --> 03:06:47,600
ENDOMETRIOSIS.

5217
03:06:47,600 --> 03:06:48,760
ANOTHER THEORY IS IT MAY RESULT 

5218
03:06:48,760 --> 03:06:54,480
FROM LOCAL TISSUE THAT UNDER 

5219
03:06:54,480 --> 03:06:56,840
GOES CHANGES OR METAPLAGIA.

5220
03:06:56,840 --> 03:07:00,240
THE THIRD IS DURING INTRAUTERINE

5221
03:07:00,240 --> 03:07:01,600
DEVELOPMENT TISSUE IS MISPLACED 

5222
03:07:01,600 --> 03:07:06,000
OUTSIDE THE UTERUS AND IT  

5223
03:07:06,000 --> 03:07:08,120
RESULTING IN ENDOMETRIOSIS.

5224
03:07:08,120 --> 03:07:09,720
THOUGH SEVERAL THEORIES ARE 

5225
03:07:09,720 --> 03:07:12,000
PROPOSED, ONE THEORY IS NOT ABLE

5226
03:07:12,000 --> 03:07:15,360
TO EXPLAIN ALL MANIFESTATIONS OF

5227
03:07:15,360 --> 03:07:15,760
ENDOMETRIOSIS.

5228
03:07:15,760 --> 03:07:21,200
IT'S BEEN SUGGESTS DIFFERENT 

5229
03:07:21,200 --> 03:07:28,000
TYPES MAY ARISE FROM DIFFERENT 

5230
03:07:28,000 --> 03:07:30,320
PROCESSES AND SOME FROM TISSUE 

5231
03:07:30,320 --> 03:07:30,840
OVARIAN TRANSFORMATION.

5232
03:07:30,840 --> 03:07:36,600
OTHER FACTORS MAY BE INVOLVED IN

5233
03:07:36,600 --> 03:07:39,160
THE DEVELOPMENT ENDOMETRIOSIS 

5234
03:07:39,160 --> 03:07:41,720
IT'S RECOGNIZED ESTROGEN IS 

5235
03:07:41,720 --> 03:07:43,560
CENTRAL TO THE DEVELOPMENT OF 

5236
03:07:43,560 --> 03:07:45,160
ENDOMETRIOSIS AS IT UNDER LIES 

5237
03:07:45,160 --> 03:07:47,200
KEY PATHOLOGIC PROCESSES.

5238
03:07:47,200 --> 03:07:55,240
GIVEN THE DEVELOPMENT OF EST

5239
03:07:55,240 --> 03:07:57,360
ESTROGEN COULD BE AFFECTED BY 

5240
03:07:57,360 --> 03:08:02,200
ENDOCRINE DISRUPTING.

5241
03:08:02,200 --> 03:08:05,440
IT'S DEFINED AS AN EXOGENOUS 

5242
03:08:05,440 --> 03:08:07,080
CHEMICALS OR MIXTURES OF 

5243
03:08:07,080 --> 03:08:11,160
CHEMICAL INTERFERE WITH ANY 

5244
03:08:11,160 --> 03:08:11,680
ASPECT OF HORMONE ACTION.

5245
03:08:11,680 --> 03:08:14,160
IT'S TEMPTING TO THINK OF THE 

5246
03:08:14,160 --> 03:08:15,960
SMOKESTACK FROM INDUSTRY.

5247
03:08:15,960 --> 03:08:18,000
HOWEVER, ENVIRONMENTAL CAN COME 

5248
03:08:18,000 --> 03:08:19,360
FROM EVERY DAY PRODUCTS, FOOD I 

5249
03:08:19,360 --> 03:08:21,600
AIR AND DUST IN OUR HOME 

5250
03:08:21,600 --> 03:08:22,000
ENVIRONMENT.

5251
03:08:22,000 --> 03:08:25,200
FOR EXAMPLE, THE FOOD AND 

5252
03:08:25,200 --> 03:08:31,120
BEVERAGES WE CONSUME COULD BE 

5253
03:08:31,120 --> 03:08:31,800
CONTAMI

5254
03:08:31,800 --> 03:08:32,920
CONTAMINATED.

5255
03:08:32,920 --> 03:08:37,080
BPA IS USED IN CLEAR PLASTIC OF 

5256
03:08:37,080 --> 03:08:38,640
REUSABLE FOOD AND BEVERAGE 

5257
03:08:38,640 --> 03:08:43,600
CONTAINERS AND CAN LEACH INTO 

5258
03:08:43,600 --> 03:08:48,600
FOOD AND WE CAN BE EXPOSED TO 

5259
03:08:48,600 --> 03:08:53,960
THAT WILL PHTHALATES AND THEY 

5260
03:08:53,960 --> 03:08:57,480
CAN BE USED AS FRAGRANCE 

5261
03:08:57,480 --> 03:08:59,880
FIXATIVES AND CAN BE ADDED 

5262
03:08:59,880 --> 03:09:09,200
FOREIGNING  -- SOFTENING 

5263
03:09:09,200 --> 03:09:12,720
MIXTURES AND IN FLOORS AND 

5264
03:09:12,720 --> 03:09:13,080
COATINGS.

5265
03:09:13,080 --> 03:09:15,200
THIS IS A SNAPSHOT OF THE MANY 

5266
03:09:15,200 --> 03:09:16,080
ENVIRONMENTAL CHEMICALS WE CAN 

5267
03:09:16,080 --> 03:09:20,200
BE EXPOSED TO IN OUR DAY TO DAY 

5268
03:09:20,200 --> 03:09:20,520
ENVIRONMENT.

5269
03:09:20,520 --> 03:09:22,880
AND THE GENERAL POPULATION IS 

5270
03:09:22,880 --> 03:09:24,320
WIDELY EXPOSED TO ENVIRONMENTAL 

5271
03:09:24,320 --> 03:09:24,560
CHEMICALS.

5272
03:09:24,560 --> 03:09:26,520
THIS FIGURE SHOWS IS THE NUMBER 

5273
03:09:26,520 --> 03:09:28,360
OF ENVIRONMENTAL CHEMICALS 

5274
03:09:28,360 --> 03:09:31,240
DETECTED IN BIOLOGIC SAMPLES 

5275
03:09:31,240 --> 03:09:32,920
FROM A NATIONALLY REPRESENTATIVE

5276
03:09:32,920 --> 03:09:35,760
SAMPLE OF U.S. PREGNANT WOMEN.

5277
03:09:35,760 --> 03:09:36,800
STUDYING ENVIRONMENTAL EXPOSURE 

5278
03:09:36,800 --> 03:09:39,040
AND ENDOMETRIOSIS IS 

5279
03:09:39,040 --> 03:09:39,360
CHALLENGING.

5280
03:09:39,360 --> 03:09:42,000
ONE OF THE BIGGEST CHALLENGES IS

5281
03:09:42,000 --> 03:09:45,200
THAT ENDOMETRIOSIS CAN ONLY BE 

5282
03:09:45,200 --> 03:09:47,240
DEFINITIVELY DIAGNOSED BY 

5283
03:09:47,240 --> 03:09:50,200
SURGICAL VISUALIZATION BY A 

5284
03:09:50,200 --> 03:09:51,480
PROCEDURE CALLED LAPAROSCOPY.

5285
03:09:51,480 --> 03:09:56,880
WE DON'T HAVE A WAY TO 

5286
03:09:56,880 --> 03:10:00,600
NON-INVASIVELY SCREEN AND FOLLOW

5287
03:10:00,600 --> 03:10:02,360
INDIVIDUALS FOR THE DEVELOPMENT 

5288
03:10:02,360 --> 03:10:04,040
COLLECT SAMPLES DURING THE 

5289
03:10:04,040 --> 03:10:05,360
EXPOSURE WINDOWS PRIOR TO 

5290
03:10:05,360 --> 03:10:11,000
DISEASE DEVELOPMENT SUCH AS AN 

5291
03:10:11,000 --> 03:10:12,320
EPIDEMIOLOGIC PERSPECTIVE COHORT

5292
03:10:12,320 --> 03:10:12,560
STUDY.

5293
03:10:12,560 --> 03:10:15,720
THE CASE CONTROL STUDY DESIGN IS

5294
03:10:15,720 --> 03:10:16,960
FREQUENTLY USED.

5295
03:10:16,960 --> 03:10:18,760
THE APPROACH TO HOW PARTICIPANTS

5296
03:10:18,760 --> 03:10:21,040
ARE SELECTED IS IMPORTANT FOR 

5297
03:10:21,040 --> 03:10:22,760
ROBUST RESULTS AND MINIMIZING 

5298
03:10:22,760 --> 03:10:25,400
BIAS KNOWN AS SELECTION BIAS.

5299
03:10:25,400 --> 03:10:27,880
IDEALLY WE WANT TO FIRST 

5300
03:10:27,880 --> 03:10:30,000
IDENTIFY THE STUDY POPULATION.

5301
03:10:30,000 --> 03:10:32,920
SECOND, IDENTIFY CASE ARE ARISE 

5302
03:10:32,920 --> 03:10:34,600
FROM THE STUDY POPULATION.

5303
03:10:34,600 --> 03:10:37,560
THIRD, RANDOMLY SAMPLE FROM THE 

5304
03:10:37,560 --> 03:10:39,960
UNDERLYING STUDY POPULATION TO 

5305
03:10:39,960 --> 03:10:41,760
SELECT CONTROL.

5306
03:10:41,760 --> 03:10:43,440
THIS IS IMPORTANT AS CONTROLS 

5307
03:10:43,440 --> 03:10:45,800
REPRESENT THE FREQUENCY OF 

5308
03:10:45,800 --> 03:10:47,160
EXPOSURE FROM THE UNDERLYING 

5309
03:10:47,160 --> 03:10:48,520
POPULATION THAT GIVE RISE TO 

5310
03:10:48,520 --> 03:10:48,720
CASES.

5311
03:10:48,720 --> 03:10:50,640
HOWEVER, GIVEN SURGERY IS NEEDED

5312
03:10:50,640 --> 03:10:53,880
TO IDENTIFY CASES, MOST STUDIES 

5313
03:10:53,880 --> 03:10:56,600
OF ENDOMETRIOSIS HAVE INSTEAD 

5314
03:10:56,600 --> 03:10:57,760
FIRST IDENTIFIED ENDOMETRIOSIS 

5315
03:10:57,760 --> 03:11:00,120
CASES AMONG PATIENTS UNDERGOING 

5316
03:11:00,120 --> 03:11:00,360
SURGERY.

5317
03:11:00,360 --> 03:11:02,600
THEN THESE CASES ARE COMPARED TO

5318
03:11:02,600 --> 03:11:05,440
OTHER PATIENTS UNDERGOING 

5319
03:11:05,440 --> 03:11:07,120
SURGERY WHO ARE NOT DIAGNOSED 

5320
03:11:07,120 --> 03:11:07,720
WITH ENDOMETRIOSIS.

5321
03:11:07,720 --> 03:11:09,640
THE ISSUE WITH THIS APPROACH IS 

5322
03:11:09,640 --> 03:11:12,160
SELECTING NON-CASES FROM 

5323
03:11:12,160 --> 03:11:13,240
PATIENTS UNDERGOING SURGERY IS 

5324
03:11:13,240 --> 03:11:17,240
THESE PATIENTS HAVE AN 

5325
03:11:17,240 --> 03:11:19,080
INDICATION WARRANTING INCLUDING 

5326
03:11:19,080 --> 03:11:21,200
MENSTRUAL IRREGULARITIES, 

5327
03:11:21,200 --> 03:11:23,960
UTERINE FIBROIDS AND OVARIAN 

5328
03:11:23,960 --> 03:11:29,120
CYSTS THAT MAY BE AFFECTED BY 

5329
03:11:29,120 --> 03:11:30,080
ENDOCRINE-DISRUPTING CHEMICALS.

5330
03:11:30,080 --> 03:11:32,600
THIS GROUP OF PATIENTS WITHOUT 

5331
03:11:32,600 --> 03:11:34,080
ENDOMETRIOSIS MAY NOT REPRESENT 

5332
03:11:34,080 --> 03:11:36,600
THE FREQUENCY OF ENVIRONMENTAL 

5333
03:11:36,600 --> 03:11:37,800
CHEMICAL EXPOSURE IN THE 

5334
03:11:37,800 --> 03:11:39,160
UNDERLYING POPULATION THAT GIVE 

5335
03:11:39,160 --> 03:11:39,880
RISE TO CASES.

5336
03:11:39,880 --> 03:11:41,400
THE RESULTING BIAS CAN OBSCURE 

5337
03:11:41,400 --> 03:11:48,320
THE ABILITY TO UNDERSTAND THE 

5338
03:11:48,320 --> 03:11:48,800
ASSOCIATION BETWEEN 

5339
03:11:48,800 --> 03:11:49,520
ENDOMETRIOSIS AND STUDIES.

5340
03:11:49,520 --> 03:11:51,760
THIS IS WHERE THE WOMEN'S RISK 

5341
03:11:51,760 --> 03:11:53,680
OF THE STUDY HAS MADE AN 

5342
03:11:53,680 --> 03:11:55,000
IMPORTANT CONTRIBUTION TO THE 

5343
03:11:55,000 --> 03:11:57,880
STUDY OF ENVIRONMENTAL RISK 

5344
03:11:57,880 --> 03:11:58,680
FACTORS IN ENDOMETRIOSIS.

5345
03:11:58,680 --> 03:12:01,160
REN WAS A POPULATION-BASED CASE 

5346
03:12:01,160 --> 03:12:02,320
CONTROL STUDY OF ENDOMETRIOSIS 

5347
03:12:02,320 --> 03:12:03,960
THAT WAS CONDUCTED AMONG 

5348
03:12:03,960 --> 03:12:07,440
ENROLLEES OF AN INTEGRATED 

5349
03:12:07,440 --> 03:12:08,640
HEALTH CARE SYSTEM PROVIDING 

5350
03:12:08,640 --> 03:12:13,520
BOTH INSURANCE COVERAGE AND 

5351
03:12:13,520 --> 03:12:14,880
HEALTH CARE IN WASHINGTON STATE.

5352
03:12:14,880 --> 03:12:18,640
THIS ENTITY WAS KNOWN AS GROUP 

5353
03:12:18,640 --> 03:12:19,480
HEALTH COOPERATIVE.

5354
03:12:19,480 --> 03:12:23,000
IT'S NOW KNOWN AS KAISER 

5355
03:12:23,000 --> 03:12:24,720
PERMANENTE OF WASHINGTON.

5356
03:12:24,720 --> 03:12:28,600
IT WAS DESIGNED BY A PROFESSOR 

5357
03:12:28,600 --> 03:12:34,880
EMERITUS AT THE UNIVERSITY OF 

5358
03:12:34,880 --> 03:12:35,480
WASHINGTON.

5359
03:12:35,480 --> 03:12:39,320
THE STUDY WAS FUNDED BY AN R01 

5360
03:12:39,320 --> 03:12:40,400
GRANT FROM NICHD.

5361
03:12:40,400 --> 03:12:42,720
FOLLOWING THE IDEAL APPROACH TO 

5362
03:12:42,720 --> 03:12:43,520
SELECTING PARTICIPANTS IN THE 

5363
03:12:43,520 --> 03:12:46,720
CASE CONTROL STUDY IN REN, THE 

5364
03:12:46,720 --> 03:12:49,560
STUDY POPULATION WAS IDENTIFIED 

5365
03:12:49,560 --> 03:12:51,080
FIRST.

5366
03:12:51,080 --> 03:12:53,960
PREMENOPAUSAL ENROLLEES 18 TO 49

5367
03:12:53,960 --> 03:12:56,600
WITH AN INTACT UTERUS AT LEAST 

5368
03:12:56,600 --> 03:12:58,600
ONE OVARY AND NO PREVIOUS 

5369
03:12:58,600 --> 03:13:01,560
HISTORY OF DIAGNOSIS AND 

5370
03:13:01,560 --> 03:13:04,440
ENROLLED IN THE INTEGRATED 

5371
03:13:04,440 --> 03:13:06,880
HEALTH SYSTEM FORMED THE STUDY 

5372
03:13:06,880 --> 03:13:07,520
BASE.

5373
03:13:07,520 --> 03:13:08,920
ENDOMETRIOSIS CASES WERE 

5374
03:13:08,920 --> 03:13:11,480
IDENTIFIED AND ENROLLEES WERE 

5375
03:13:11,480 --> 03:13:12,600
DIAGNOSED FOR THE FIRST TIME 

5376
03:13:12,600 --> 03:13:16,080
BETWEEN APRIL 1996 AND MARCH 

5377
03:13:16,080 --> 03:13:16,320
2001.

5378
03:13:16,320 --> 03:13:18,440
THE DIAGNOSIS WAS CONFIRMED BY 

5379
03:13:18,440 --> 03:13:21,160
MEDICAL RECORD REVIEW INCLUDING 

5380
03:13:21,160 --> 03:13:24,480
OF OPERATIVE NODES AND PATHOLOGY

5381
03:13:24,480 --> 03:13:28,400
REPORT INDICATING ENDOMETRIOSIS 

5382
03:13:28,400 --> 03:13:29,400
THROUGH DIRECT SURGICAL 

5383
03:13:29,400 --> 03:13:29,760
VISUALIZATION.

5384
03:13:29,760 --> 03:13:31,880
FROM THE STUDY BASE, CONTROLS 

5385
03:13:31,880 --> 03:13:33,760
WERE DIRECTLY AND RANDOMLY 

5386
03:13:33,760 --> 03:13:36,040
SAMPLED FROM THE COMPUTERIZED 

5387
03:13:36,040 --> 03:13:38,880
GROUP HEALTH ENROLLMENT 

5388
03:13:38,880 --> 03:13:39,840
DATABASES THAT WERE FREQUENCY 

5389
03:13:39,840 --> 03:13:43,080
MATCHED TO CASE IN FIVE-YEAR AGE

5390
03:13:43,080 --> 03:13:43,320
GROUPS.

5391
03:13:43,320 --> 03:13:45,160
IN REN THE STATE WAS NOT THE 

5392
03:13:45,160 --> 03:13:46,840
DATE OF DIAGNOSIS BUT RATHER THE

5393
03:13:46,840 --> 03:13:49,880
DATE OF FIRST VISIT TO GROUP 

5394
03:13:49,880 --> 03:13:50,920
HEALTH FOR SYMPTOMS LEADING TO 

5395
03:13:50,920 --> 03:13:53,160
ENDOMETRIOSIS DIAGNOSIS.

5396
03:13:53,160 --> 03:13:58,480
IN REN, CASES ALSO NEEDED TO 

5397
03:13:58,480 --> 03:14:04,000
MEET THE DEFINITION OF DEFINITE 

5398
03:14:04,000 --> 03:14:11,840
FOR POSSIBLE ENDOMEETRY OTIC 

5399
03:14:11,840 --> 03:14:13,960
DISEASE AND ENDOMETRIOSIS THAT 

5400
03:14:13,960 --> 03:14:17,440
HAD PROGRESSED TO INCREASE THE 

5401
03:14:17,440 --> 03:14:25,320
LIKELIHOOD OF OBSERVIING 

5402
03:14:25,320 --> 03:14:27,120
OBSERVATIONS AND MINIMIZE SOME 

5403
03:14:27,120 --> 03:14:27,480
CONTROLS.

5404
03:14:27,480 --> 03:14:29,560
THIS ALSO MEANT DATA WAS 

5405
03:14:29,560 --> 03:14:33,160
AVAILABLE ON OVARIAN AND 

5406
03:14:33,160 --> 03:14:35,480
NON-OVARIAN PELVIC ENDOMETRIOSIS

5407
03:14:35,480 --> 03:14:37,680
WHICH MAY HAVE SEPARATE 

5408
03:14:37,680 --> 03:14:39,000
ETIOLOGIC PATHWAYS.

5409
03:14:39,000 --> 03:14:45,400
THE WREN STUDY INCLUDED 

5410
03:14:45,400 --> 03:14:45,640
CONTROLS.

5411
03:14:45,640 --> 03:14:48,600
THE MAIN STUDY WAS AN IN-PERSON 

5412
03:14:48,600 --> 03:14:50,280
STRUCTURED INTERVIEW CONDUCTED 

5413
03:14:50,280 --> 03:14:52,760
BY A TRAINED FEMALE INTERVIEWERS

5414
03:14:52,760 --> 03:14:55,320
FROM THE FRED HUTCHINGSON CANCER

5415
03:14:55,320 --> 03:14:57,160
CENTER IN SEATTLE, WASHINGTON.

5416
03:14:57,160 --> 03:14:59,480
THE INTERVIEWS WERE AT THE 

5417
03:14:59,480 --> 03:15:00,760
PARTICIPANT'S HOME OR FRED HUTCH

5418
03:15:00,760 --> 03:15:02,680
AND DATA WAS COLLECTED ON A 

5419
03:15:02,680 --> 03:15:04,920
RANGE OF TOPICS FROM MENSTRUAL, 

5420
03:15:04,920 --> 03:15:06,600
REPRODUCTIVE AND CONTRACEPTIVE 

5421
03:15:06,600 --> 03:15:09,200
HISTORY TO EARLY LIFE FACTORS 

5422
03:15:09,200 --> 03:15:12,400
AND OCCUPATIONAL EXPOSURES.

5423
03:15:12,400 --> 03:15:15,320
A VARIETY OF METHODS WERE USED 

5424
03:15:15,320 --> 03:15:16,560
TO HELP PARTICIPANT RECALL.

5425
03:15:16,560 --> 03:15:19,440
A STUDY BY THE 

5426
03:15:19,440 --> 03:15:20,360
U.S. ENVIRONMENTAL PROTECTION 

5427
03:15:20,360 --> 03:15:23,880
AGENCY SUPPORT THE COLLECTION OF

5428
03:15:23,880 --> 03:15:29,720
BLOOD SAMPLES AND 34 NON-PCB 

5429
03:15:29,720 --> 03:15:30,000
SERUM.

5430
03:15:30,000 --> 03:15:31,920
AS PART OF THE GRANT, URINE 

5431
03:15:31,920 --> 03:15:33,480
SAMPLES WERE ALSO COLLECTED AND 

5432
03:15:33,480 --> 03:15:33,720
ARCHIVED.

5433
03:15:33,720 --> 03:15:35,960
THE URINE SAMPLES WERE ANALYZED 

5434
03:15:35,960 --> 03:15:40,440
FOR BPA FUNDED BY AN R03 GRANT 

5435
03:15:40,440 --> 03:15:45,520
BY NIEHS AND METABOLITES FUNDED 

5436
03:15:45,520 --> 03:15:47,160
AT THE UNIVERSITY OF WASHINGTON.

5437
03:15:47,160 --> 03:15:49,480
IN THE WREN STUDY, THE MEDIAN 

5438
03:15:49,480 --> 03:15:52,280
AGE WAS 39 YEARS AND WAS SIMILAR

5439
03:15:52,280 --> 03:15:55,960
BETWEEN CASES AN CONTROLS SINCE 

5440
03:15:55,960 --> 03:15:57,000
CONTROLS WERE FREQUENCY MATCHED.

5441
03:15:57,000 --> 03:15:59,280
THE STUDY POPULATION WAS 

5442
03:15:59,280 --> 03:15:59,960
PREDOMINANTLY WHITE NON-HISPANIC

5443
03:15:59,960 --> 03:16:03,000
AND CASES CONTROLS WERE 

5444
03:16:03,000 --> 03:16:04,600
GENERALLY SIMILAR ON SEVERAL 

5445
03:16:04,600 --> 03:16:06,680
DEMOGRAPHIC FACTORS INCLUDING 

5446
03:16:06,680 --> 03:16:07,560
EDUCATION, ANNUAL HOUSEHOLD 

5447
03:16:07,560 --> 03:16:11,400
INCOME, BMI AND SMOKING.

5448
03:16:11,400 --> 03:16:12,160
HOWEVER, ENDOMETRIOSIS CASES 

5449
03:16:12,160 --> 03:16:14,840
MORE FREQUENTLY REPORTED A 

5450
03:16:14,840 --> 03:16:17,840
HISTORY OF NO PRIOR BIRTHS.

5451
03:16:17,840 --> 03:16:19,400
THE SOCIO DEMOGRAPHIC OF THE 

5452
03:16:19,400 --> 03:16:21,040
WREN NEARED OF THAT THE 

5453
03:16:21,040 --> 03:16:22,120
INTEGRATED HEALTH PLAN 

5454
03:16:22,120 --> 03:16:25,680
POPULATION AND THE SURROUNDING 

5455
03:16:25,680 --> 03:16:27,920
PUGET SOUND AREA.

5456
03:16:27,920 --> 03:16:31,080
I WANT TO POINT OUT MANY OF THE 

5457
03:16:31,080 --> 03:16:31,760
ENVIRONMENTAL CHEMICALS MEASURED

5458
03:16:31,760 --> 03:16:34,400
IN WREN PARTICIPANTS WERE 

5459
03:16:34,400 --> 03:16:36,400
DETECTABLE IN MANY IF NOT ALL 

5460
03:16:36,400 --> 03:16:37,080
PARTICIPANTS.

5461
03:16:37,080 --> 03:16:41,760
BPA AND PHTHALATES ARE 

5462
03:16:41,760 --> 03:16:43,200
NON-PERSISTENT CHEMICALS 

5463
03:16:43,200 --> 03:16:44,480
SECRETED IN THE MATTER OF HOURS 

5464
03:16:44,480 --> 03:16:45,200
AFTER EXPOSURE.

5465
03:16:45,200 --> 03:16:47,760
GIVEN HOW COMMONLY THEY WERE 

5466
03:16:47,760 --> 03:16:50,240
DETECTED IN URINE SUGGESTS 

5467
03:16:50,240 --> 03:16:51,840
CHRONIC EXPOSURE.

5468
03:16:51,840 --> 03:16:53,720
ORGANO CHLORINE PESTICIDE 

5469
03:16:53,720 --> 03:16:55,720
PERSISTENT CHEMICALS THAT HAVE A

5470
03:16:55,720 --> 03:16:56,960
LONG HALF LIFE OF YEARS.

5471
03:16:56,960 --> 03:16:59,600
I'M GOING HIGHLIGHT A FEW OF THE

5472
03:16:59,600 --> 03:17:01,160
FINDINGS FROM ACROSS THE WREN 

5473
03:17:01,160 --> 03:17:01,400
STUDIES.

5474
03:17:01,400 --> 03:17:03,920
WE OBSERVED THAT EXPOSURE STO 

5475
03:17:03,920 --> 03:17:07,760
BETA HCH AND ORGANOCHLORINE 

5476
03:17:07,760 --> 03:17:10,320
PESTICIDE WAS ASSOCIATED WITH 

5477
03:17:10,320 --> 03:17:12,600
TWICE THE RISK OF ENDOMETRIOSIS 

5478
03:17:12,600 --> 03:17:14,920
PRIMARILY OVARIAN ENDOMETRIOSIS.

5479
03:17:14,920 --> 03:17:21,400
BETA HCH IS TECHNICAL GRADE HCH 

5480
03:17:21,400 --> 03:17:26,560
WAS AN INSECTICIDE IN THE UNITED

5481
03:17:26,560 --> 03:17:29,000
STATES UNTIL THE IS THE 80s.

5482
03:17:29,000 --> 03:17:35,080
AND WITH EACH INCREASE IN 

5483
03:17:35,080 --> 03:17:36,360
NON-PCBTRATIONS IT WAS 

5484
03:17:36,360 --> 03:17:39,080
ASSOCIATED WITH A 30% INCREASE 

5485
03:17:39,080 --> 03:17:41,280
RISK OF ENDOMETRIOSIS.

5486
03:17:41,280 --> 03:17:44,200
PCBs WERE KNOWN IN COOLANTS AN 

5487
03:17:44,200 --> 03:17:45,400
LUBRICANTS AND ELECTRICAL 

5488
03:17:45,400 --> 03:17:52,480
EQUIPMENT LIKE TRANSFORMERS AND 

5489
03:17:52,480 --> 03:17:54,760
UNTIL THEIR USE WAS BANNED IN 

5490
03:17:54,760 --> 03:17:57,240
THE U.S. AND PCBs ACCUMULATE IN 

5491
03:17:57,240 --> 03:17:59,880
THE FATTY TISSUE OF ANIMALS AND 

5492
03:17:59,880 --> 03:18:01,440
HUMAN EXPOSURE PRIMARILY THROUGH

5493
03:18:01,440 --> 03:18:03,240
THE CONSUMPTION OF ANIMAL AND 

5494
03:18:03,240 --> 03:18:04,440
DAIRY PRODUCTS.

5495
03:18:04,440 --> 03:18:07,600
EXPOSURE TO THE PHTHALATE 

5496
03:18:07,600 --> 03:18:09,880
METABOLITE WAS ASSOCIATED WITH A

5497
03:18:09,880 --> 03:18:13,480
70% DECREASED RISK OF 

5498
03:18:13,480 --> 03:18:13,920
ENDOMETRIOSIS.

5499
03:18:13,920 --> 03:18:19,360
THOUGH WE OBSERVED A DECREASED 

5500
03:18:19,360 --> 03:18:20,560
RISK IT DOES NOT MEAN EXPOSURE 

5501
03:18:20,560 --> 03:18:24,240
IS PROTECTIVE.

5502
03:18:24,240 --> 03:18:26,760
DEHP IS USED FOR SOFTENING AND 

5503
03:18:26,760 --> 03:18:28,800
ADDING FLEXIBILITY TO PLASTIC 

5504
03:18:28,800 --> 03:18:31,800
PRODUCTS AND THE EXHIBITED TOXIC

5505
03:18:31,800 --> 03:18:39,280
EFFECTS ON THE OVARIES INCLUDING

5506
03:18:39,280 --> 03:18:41,480
LOWERING HORMONES AND IT WAS 

5507
03:18:41,480 --> 03:18:44,000
ASSOCIATED WITH THREE TIMES THE 

5508
03:18:44,000 --> 03:18:45,240
RISK OF ENDOMETRIOSIS 

5509
03:18:45,240 --> 03:18:47,480
PARTICULARLY NON-OVARIAN PELVIC 

5510
03:18:47,480 --> 03:18:48,240
ENDOMETRIOSIS.

5511
03:18:48,240 --> 03:18:51,000
BPA IS USED TO MANUFACTURE CLEAR

5512
03:18:51,000 --> 03:18:53,040
HARD PLASTIC FOUND IN REUSABLE 

5513
03:18:53,040 --> 03:18:56,400
FOOD AND BEVERAGE CONTAINERS AND

5514
03:18:56,400 --> 03:19:01,040
USED IN EPOXY RESIN THAT LINE 

5515
03:19:01,040 --> 03:19:05,560
FOOD AND BEVERAGE CANS.

5516
03:19:05,560 --> 03:19:06,520
AND ENVIRONMENTAL EXPOSURE CAN 

5517
03:19:06,520 --> 03:19:09,920
INCLUDE DIET, MEDICATION AND 

5518
03:19:09,920 --> 03:19:10,920
OCCUPATIONAL EXPOSURES.

5519
03:19:10,920 --> 03:19:13,640
SOY FORMULA CONTAINS PHYTO 

5520
03:19:13,640 --> 03:19:14,040
ESTROGENS.

5521
03:19:14,040 --> 03:19:15,240
IN WREN THE PARTICIPANT'S MOTHER

5522
03:19:15,240 --> 03:19:17,800
WAS CONTACTED AND ASKED WHETHER 

5523
03:19:17,800 --> 03:19:19,120
THE PARTICIPANT WAS FED SOY 

5524
03:19:19,120 --> 03:19:20,520
FORMULA AS AN INFANT.

5525
03:19:20,520 --> 03:19:24,120
WE OBSERVED THAT SOY FORMULA 

5526
03:19:24,120 --> 03:19:27,240
DURING INFANCY WAS ASSOCIATED 

5527
03:19:27,240 --> 03:19:28,400
WITH TWICE THE RISK OF 

5528
03:19:28,400 --> 03:19:30,000
ENDOMETRIOSIS.

5529
03:19:30,000 --> 03:19:31,040
THE PARTICIPANT'S MOTHER WAS 

5530
03:19:31,040 --> 03:19:33,200
ALSO ASKED ABOUT THE USE OF 

5531
03:19:33,200 --> 03:19:35,440
HORMONE MEDICATION DES WHEN 

5532
03:19:35,440 --> 03:19:36,600
PREGNANT WITH THE PARTICIPANT.

5533
03:19:36,600 --> 03:19:39,200
DES IS A POTENT ESTROGEN THAT 

5534
03:19:39,200 --> 03:19:40,360
WAS PRESCRIBED TO WOMEN IN THE 

5535
03:19:40,360 --> 03:19:42,440
U.S. FOR THE PREVENTION OF 

5536
03:19:42,440 --> 03:19:45,840
MISCARRIAGE AND OTHER PREGNANCY 

5537
03:19:45,840 --> 03:19:49,480
COMPLICATIONS UNTIL THE '70s 

5538
03:19:49,480 --> 03:19:53,040
WHEN IT WAS FOUND TO INCREASE 

5539
03:19:53,040 --> 03:19:55,080
THE RISK OF VAGINAL CANCER AND 

5540
03:19:55,080 --> 03:19:58,480
IT WAS ASSOCIATED WITH TWICE THE

5541
03:19:58,480 --> 03:19:59,840
RISK OF ENDOMETRIOSIS.

5542
03:19:59,840 --> 03:20:02,960
NIGHT SHIFT WORK IS ONE CAUSE OF

5543
03:20:02,960 --> 03:20:03,840
CIRCADIAN DISRUPTION AND FOUND 

5544
03:20:03,840 --> 03:20:08,600
TO ALTER ESTROGEN SECRETION AND 

5545
03:20:08,600 --> 03:20:09,200
METABOLISM.

5546
03:20:09,200 --> 03:20:12,160
THEY WERE ASKED ABOUT EVERY JOB 

5547
03:20:12,160 --> 03:20:14,360
HELD AND THE SHIFT WORKS FROM 

5548
03:20:14,360 --> 03:20:14,760
18.

5549
03:20:14,760 --> 03:20:17,160
ANY NIGHT SHIFT WAS ASSOCIATED 

5550
03:20:17,160 --> 03:20:21,120
WITH A 50% INCREASED RISK OF 

5551
03:20:21,120 --> 03:20:22,000
ENDOMETRIOSIS RISK.

5552
03:20:22,000 --> 03:20:24,600
MOVING THE FIELD FORWARD 

5553
03:20:24,600 --> 03:20:25,600
EXAMINEXAMINE

5554
03:20:25,600 --> 03:20:28,120
ING ENVIRONMENTAL CHEMICALS AND 

5555
03:20:28,120 --> 03:20:30,680
ENDOMETRIOSIS RISK IS FOLLOWED 

5556
03:20:30,680 --> 03:20:33,120
BY COLLECTION OF BIOLOGIC 

5557
03:20:33,120 --> 03:20:35,040
SAMPLES AFTER DIAGNOSIS.

5558
03:20:35,040 --> 03:20:37,920
CASE OF A URINE SAMPLE TO LOOK 

5559
03:20:37,920 --> 03:20:39,480
AT EXPOSURE TO NON-PERSISTENT 

5560
03:20:39,480 --> 03:20:39,760
CHEMICALS.

5561
03:20:39,760 --> 03:20:43,240
THIS WAS CONDUCTED BEFORE THE 

5562
03:20:43,240 --> 03:20:44,320
STATISTICAL METHODS FOR 

5563
03:20:44,320 --> 03:20:46,040
EVALUATING EXPOSURE TO CHEMICAL 

5564
03:20:46,040 --> 03:20:46,320
MIXTURES.

5565
03:20:46,320 --> 03:20:48,200
THE POTENTIAL FOR UNDIAGNOSED 

5566
03:20:48,200 --> 03:20:49,040
DISEASE AMONG CONTROLS.

5567
03:20:49,040 --> 03:20:54,200
THOUGH WE ESTIMATE LESS THAN 2% 

5568
03:20:54,200 --> 03:20:56,280
CONTROLS MAY HAVE HAD 

5569
03:20:56,280 --> 03:20:57,680
UNDIAGNOSED ENDOMETRIOTIC 

5570
03:20:57,680 --> 03:20:57,880
DISEASE.

5571
03:20:57,880 --> 03:21:01,880
THERE WAS A POPULATION-BASED 

5572
03:21:01,880 --> 03:21:02,640
SAMPLING MINIMIZING HOW 

5573
03:21:02,640 --> 03:21:04,560
PARTICIPANTS WERE SELECTED AND 

5574
03:21:04,560 --> 03:21:07,120
WE HAD THE COLLECTION OF 

5575
03:21:07,120 --> 03:21:10,160
BIOLOGIC SAMPLES FOR CHEMICAL 

5576
03:21:10,160 --> 03:21:11,760
MEASUREMENTS AND SAMPLES THAT 

5577
03:21:11,760 --> 03:21:14,160
WERE COLLECTED BEFORE AWARENESS 

5578
03:21:14,160 --> 03:21:18,760
OF ENDOCRINE DISRUPTION 

5579
03:21:18,760 --> 03:21:20,160
CHEMICALS CHANGING HABITS AFTER 

5580
03:21:20,160 --> 03:21:21,000
DIAGNOSED.

5581
03:21:21,000 --> 03:21:24,200
WE HAD DATA ON OVARIAN AND 

5582
03:21:24,200 --> 03:21:25,480
NON-OVARIAN PELVIC ENDOMETRIOSIS

5583
03:21:25,480 --> 03:21:27,120
WHICH MAY HAVE A DIFFERENT 

5584
03:21:27,120 --> 03:21:30,080
RELATIONSHIP WITH ENVIRONMENTAL 

5585
03:21:30,080 --> 03:21:31,080
EXPOSURES.

5586
03:21:31,080 --> 03:21:32,600
SEVERAL COMPREHENSIVE REVIEWS 

5587
03:21:32,600 --> 03:21:35,280
WERE CONDUCTED ON ENVIRONMENTAL 

5588
03:21:35,280 --> 03:21:36,520
CHEMICALS AND ENDOMETRIOSIS 

5589
03:21:36,520 --> 03:21:38,400
INCLUDING A RECENT REVIEW FROM 

5590
03:21:38,400 --> 03:21:38,680
2020.

5591
03:21:38,680 --> 03:21:40,920
A REPORT OF COMMON CONCLUSION.

5592
03:21:40,920 --> 03:21:44,200
THE RESULTS ACROSS STUDIES ARE 

5593
03:21:44,200 --> 03:21:44,560
INCONCLUSIVE.

5594
03:21:44,560 --> 03:21:48,560
THE APPROACH TO STUDYING 

5595
03:21:48,560 --> 03:21:52,600
POPULATION SAMPLING, THE USE OF 

5596
03:21:52,600 --> 03:21:54,960
BIOLOGIC SAMPLES AND THE 

5597
03:21:54,960 --> 03:22:00,320
APPROACH TO CAL OF STATISTICAL 

5598
03:22:00,320 --> 03:22:01,920
ANALYSIS AND MANY LIKELY 

5599
03:22:01,920 --> 03:22:02,920
CONTRIBUTED TO THE DISPARATE 

5600
03:22:02,920 --> 03:22:03,280
RESULT.

5601
03:22:03,280 --> 03:22:06,320
IN THE PAST DECADE THERE'S BEEN 

5602
03:22:06,320 --> 03:22:07,560
INNOVATIVE APPROACHES TO CONDUCT

5603
03:22:07,560 --> 03:22:09,320
POPULATION-BASED STUDIES OF 

5604
03:22:09,320 --> 03:22:11,120
ENVIRONMENTAL CHEMICALS AND 

5605
03:22:11,120 --> 03:22:12,360
ENDOMETRIOSIS YIELDING SOME 

5606
03:22:12,360 --> 03:22:13,520
CONSISTENT RESULTS ACROSS 

5607
03:22:13,520 --> 03:22:14,600
POPULATION STUDIES.

5608
03:22:14,600 --> 03:22:17,760
SO THIS LEADS KNOW MY FIRST 

5609
03:22:17,760 --> 03:22:18,640
RECOMMENDATION OF FIVE 

5610
03:22:18,640 --> 03:22:20,040
RECOMMENDATIONS TO MOVE THE 

5611
03:22:20,040 --> 03:22:21,360
FIELD FORWARD.

5612
03:22:21,360 --> 03:22:26,320
FIRST, I RECOMMEND USING A VALID

5613
03:22:26,320 --> 03:22:28,400
EPIDEMIOLOGIC STUDY DESIGN FOR 

5614
03:22:28,400 --> 03:22:36,640
REROBUST  -- ROBUST RESULT BY 

5615
03:22:36,640 --> 03:22:40,280
LARGE EPIDEMIOLOGIC COHORTS 

5616
03:22:40,280 --> 03:22:41,520
MEASURING CHEMICALS OR COLLECTED

5617
03:22:41,520 --> 03:22:44,320
SAMPLES PROSPECTIVELY.

5618
03:22:44,320 --> 03:22:46,040
SECOND, I RECOMMEND MEASURING 

5619
03:22:46,040 --> 03:22:47,480
EXPOSURE DURING THE RELEVANT 

5620
03:22:47,480 --> 03:22:51,000
WINDOW OF THE DEVELOPMENT OF 

5621
03:22:51,000 --> 03:22:51,440
ENDOMETRIOSIS.

5622
03:22:51,440 --> 03:22:55,960
AS THE WINDOWS COULD INCLUDE IN 

5623
03:22:55,960 --> 03:22:58,440
UTERO AND INFANCY AND NOVEL 

5624
03:22:58,440 --> 03:22:59,440
APPROACHES ARE NEEDED INCLUDING 

5625
03:22:59,440 --> 03:23:02,440
THE USE OF EXISTING SAMPLES.

5626
03:23:02,440 --> 03:23:06,040
I'M THINKING NEWBORN DRY BLOOD 

5627
03:23:06,040 --> 03:23:09,600
SPOTS COLLECTED AND BABY TEETH 

5628
03:23:09,600 --> 03:23:12,360
LOSS CAN BE MEASURED FOR 

5629
03:23:12,360 --> 03:23:13,040
ENVIRONMENTAL CHEMICALS AS WELL 

5630
03:23:13,040 --> 03:23:14,960
AS LINKAGE WITH HISTORICAL DATA 

5631
03:23:14,960 --> 03:23:20,560
SUCH AS AIR POLLUTION 

5632
03:23:20,560 --> 03:23:21,520
MONITORING.

5633
03:23:21,520 --> 03:23:24,880
THIRD, I RECOMMEND 

5634
03:23:24,880 --> 03:23:27,120
DISAGGREGATING ENDOMETRIOSIS AND

5635
03:23:27,120 --> 03:23:32,320
LOOKING AT DIFFERENT IDEOLOGIC 

5636
03:23:32,320 --> 03:23:33,000
PATHWAYS.

5637
03:23:33,000 --> 03:23:34,640
FOURTH, I RECOMMEND 

5638
03:23:34,640 --> 03:23:35,840
UNDERSTANDING FACTOR ARE COMMON 

5639
03:23:35,840 --> 03:23:46,320
YET UNIQUE TO MEN STRATEAL 

5640
03:23:46,840 --> 03:23:48,080
EXPOSURES AND THE ROLE OF 

5641
03:23:48,080 --> 03:23:56,840
MENSTRUAL BLOOD LOSS ON CHEMICAL

5642
03:23:56,840 --> 03:24:03,200
EXCRETION AND CONTRACEPTIVE USE 

5643
03:24:03,200 --> 03:24:09,720
AND USING TEAM SCIENCE WITH 

5644
03:24:09,720 --> 03:24:10,720
EPIDEMIOLOGISTS, STATISTICIAN 

5645
03:24:10,720 --> 03:24:13,240
AND COMMUNITY MEMBERS.

5646
03:24:13,240 --> 03:24:16,160
TO CONCLUDE I'D LIKE TO 

5647
03:24:16,160 --> 03:24:16,880
ACKNOWLEDGE THE RESEARCHERS 

5648
03:24:16,880 --> 03:24:17,880
INVOLVED IN THE WREN STUDY AND 

5649
03:24:17,880 --> 03:24:20,600
THE FUNDING SOURCES THAT HAVE 

5650
03:24:20,600 --> 03:24:24,840
MADE THIS RESEARCH POSSIBLE.

5651
03:24:24,840 --> 03:24:25,760
THANK YOU AND I'M HAPPY TO 

5652
03:24:25,760 --> 03:24:26,360
ADDRESS ANY QUESTIONS YOU MAY 

5653
03:24:26,360 --> 03:24:36,480
HAVE.

5654
03:24:37,160 --> 03:24:38,720
YOU CAN SUBMIT YOUR QUESTIONS BY

5655
03:24:38,720 --> 03:24:41,160
CHAT OR BY RAISING YOUR HAND AND

5656
03:24:41,160 --> 03:24:43,080
I'M HAPPY TO ADDRESS THEM.

5657
03:24:43,080 --> 03:24:44,160
WE HAVE ABOUT FIVE MINUTES FOR 

5658
03:24:44,160 --> 03:24:44,360
THIS.

5659
03:24:44,360 --> 03:24:47,200
>>IF WE DON'T HAVE TIME
FOR 

5660
03:24:47,200 --> 03:24:49,080
THAT NOW KRISTEN WE CAN DO IT AT

5661
03:24:49,080 --> 03:24:52,560
THE END BUT IT LOOKS LIKE 

5662
03:24:52,560 --> 03:24:53,680
DR. DOUTHARD HAS A QUESTION.

5663
03:24:53,680 --> 03:24:57,360
>>GREAT, THANK YOU.

5664
03:24:57,360 --> 03:25:07,600
DR. DOUTHARD.

5665
03:25:08,000 --> 03:25:11,560
>>THANK YOU VERY MUCH, 

5666
03:25:11,560 --> 03:25:12,600
DR. UPSON FOR A VERY INFORMATIVE

5667
03:25:12,600 --> 03:25:22,840
PRESENTATION.

5668
03:25:24,280 --> 03:25:26,200
I THING YOU ANSWERED MY QUESTION

5669
03:25:26,200 --> 03:25:29,640
BECAUSE I WAS GOING TO SAY 

5670
03:25:29,640 --> 03:25:32,120
SEVERAL STUDIES TALKED ABOUT 

5671
03:25:32,120 --> 03:25:36,400
PHTHALATES AN AFFECT METABOLIC 

5672
03:25:36,400 --> 03:25:37,520
PATHWAYS WITH STRESS AND AFFECT 

5673
03:25:37,520 --> 03:25:42,000
ENDOMETRIOSIS.

5674
03:25:42,000 --> 03:25:43,920
YOU HAVE OTHER STUDIES OTHER 

5675
03:25:43,920 --> 03:25:48,960
INVESTIGATIONS THAT COME UP WITH

5676
03:25:48,960 --> 03:25:54,880
DIFFERENT CONTRADICTORY 

5677
03:25:54,880 --> 03:25:55,120
FINDINGS.

5678
03:25:55,120 --> 03:25:57,520
I WAS WONDERING ARE WE CLOSER TO

5679
03:25:57,520 --> 03:25:58,720
GETTING TO UNDERSTAND THE 

5680
03:25:58,720 --> 03:26:01,080
CONTRADICTIONS AND I ASSUME THE 

5681
03:26:01,080 --> 03:26:06,920
RECOMMENDATIONS YOU MADE COULD 

5682
03:26:06,920 --> 03:26:08,400
DEFINITELY IMPROVE THE RESULTS 

5683
03:26:08,400 --> 03:26:11,480
AND MINIMIZE OR DECREASE THE 

5684
03:26:11,480 --> 03:26:12,560
RISK OF CONTRADICTORY RESULTS 

5685
03:26:12,560 --> 03:26:18,880
FOR ASSOCIATION.

5686
03:26:18,880 --> 03:26:26,080
>>YES, I'M GLAD YOU'RE 

5687
03:26:26,080 --> 03:26:27,440
HIGHLIGHTING THE DISPARATE 

5688
03:26:27,440 --> 03:26:29,120
APPROACH AND WHEN IF YOU WANT TO

5689
03:26:29,120 --> 03:26:31,120
CHARACTERIZE SOMEONE'S EXPOSURE 

5690
03:26:31,120 --> 03:26:33,400
WE NEED REPEAT URINARY SAMPLES 

5691
03:26:33,400 --> 03:26:35,880
FROM THE SAME INDIVIDUAL TO 

5692
03:26:35,880 --> 03:26:36,560
CHARACTERIZE THEIR EXPOSURE OVER

5693
03:26:36,560 --> 03:26:38,400
TIME.

5694
03:26:38,400 --> 03:26:40,520
IDEALLY WE'D LIKE TO 

5695
03:26:40,520 --> 03:26:42,080
CHARACTERIZE THAT DURING AN 

5696
03:26:42,080 --> 03:26:46,480
ETIOLOGICALLY SIMILAR WINDOW.

5697
03:26:46,480 --> 03:26:48,120
WHEN I COMPARED THE FINDINGS 

5698
03:26:48,120 --> 03:26:51,160
FROM WREN USING A 

5699
03:26:51,160 --> 03:26:51,800
POPULATION-BASED SAMPLING AS 

5700
03:26:51,800 --> 03:26:55,640
WELL AS TWO FINDINGS FROM THE 

5701
03:26:55,640 --> 03:26:57,240
NATIONAL HEALTH AND NUTRITION 

5702
03:26:57,240 --> 03:27:00,600
EXEMPTION SURVEY A NATIONALLY 

5703
03:27:00,600 --> 03:27:04,800
REPRESENTATIVIE IIE IIVE  DATA  

5704
03:27:04,800 --> 03:27:07,560
SAW THE ASSOCIATION BETWEEN THE 

5705
03:27:07,560 --> 03:27:10,080
METABOLITES OF DPHP AND 

5706
03:27:10,080 --> 03:27:10,800
DECREASED ENDOMETRIOSIS.

5707
03:27:10,800 --> 03:27:12,920
IT WAS NICE TO SEE WHEN WE HAD 

5708
03:27:12,920 --> 03:27:15,200
SIMILAR POPULATION-BASED STUDY 

5709
03:27:15,200 --> 03:27:16,760
DESIGNS THOUGH WE BOTH ONLY HAD 

5710
03:27:16,760 --> 03:27:19,320
A SINGLE MEASURE OF URINARY 

5711
03:27:19,320 --> 03:27:21,720
PHTHALATE IT WAS NICE TO SEE THE

5712
03:27:21,720 --> 03:27:25,200
CONSISTENCY BUT MOVE IT FORWARD 

5713
03:27:25,200 --> 03:27:28,640
IT WOULD BE NICE TO HAVE 

5714
03:27:28,640 --> 03:27:37,880
REPEATED MEASURES AND AT THE 

5715
03:27:37,880 --> 03:27:44,120
ETIOLOGICALLY RELEVANT WINDOW.

5716
03:27:44,120 --> 03:27:45,920
>>MAYBE LATER WE CAN
ADDRESS 

5717
03:27:45,920 --> 03:27:46,280
MORE.

5718
03:27:46,280 --> 03:27:47,400
>>ABSOLUTELY.

5719
03:27:47,400 --> 03:27:52,560
WHY DON'T WE MOVE ON TO OUR NEXT

5720
03:27:52,560 --> 03:27:54,600
SPEAKER, I WOULD LIKE TO NOW 

5721
03:27:54,600 --> 03:27:56,200
INTRODUCE MY FELLOW PANELIST 

5722
03:27:56,200 --> 03:27:57,720
DR. QUAKER HARMON.

5723
03:27:57,720 --> 03:28:00,600
DR. HARMON IS A STAFF SCIENTIST 

5724
03:28:00,600 --> 03:28:02,560
IN THE WOMEN'S HEALTH GROUP IN 

5725
03:28:02,560 --> 03:28:03,760
THE EPIDEMIOLOGY BRANCH AT THE 

5726
03:28:03,760 --> 03:28:05,640
NATIONAL INSTITUTE OF 

5727
03:28:05,640 --> 03:28:08,600
ENVIRONMENTAL HEALTH SCIENCES.

5728
03:28:08,600 --> 03:28:11,840
IN THE THIS ROLE SHE WORKS TO 

5729
03:28:11,840 --> 03:28:13,800
CONDUCT HER OWN RESEARCH AND 

5730
03:28:13,800 --> 03:28:14,960
FACILITATE THAT OF OTHERS 

5731
03:28:14,960 --> 03:28:15,920
LOOKING AT ENVIRONMENT, 

5732
03:28:15,920 --> 03:28:18,960
LIFESTYLE AND FIBROIDS WITH 

5733
03:28:18,960 --> 03:28:19,160
SELF.

5734
03:28:19,160 --> 03:28:21,600
IT'S A STUDY OF FIBROID 

5735
03:28:21,600 --> 03:28:23,120
DEVELOPMENT IN THE DETROIT-BASED

5736
03:28:23,120 --> 03:28:24,520
COHORT OF BLACK WOMEN.

5737
03:28:24,520 --> 03:28:26,200
THE RACIAL ETHNIC GROUP THAT HAS

5738
03:28:26,200 --> 03:28:29,600
THE HIGHEST HEALTH BURDEN FROM 

5739
03:28:29,600 --> 03:28:29,840
FIBOIDS.

5740
03:28:29,840 --> 03:28:32,200
HER RESEARCH HAS FOCUSSED ON 

5741
03:28:32,200 --> 03:28:33,320
FIBROID OUTCOMES ASSOCIATED WITH

5742
03:28:33,320 --> 03:28:36,640
VITAMIN D AND THE USE OF 

5743
03:28:36,640 --> 03:28:39,240
HORMONAL CONTRASEPTIVES AND 

5744
03:28:39,240 --> 03:28:42,680
LOOKING AT GEOSPATIAL AND 

5745
03:28:42,680 --> 03:28:45,240
ENVIRONMENTAL EXPOSURES AND HAS 

5746
03:28:45,240 --> 03:28:47,040
INVESTIGATED CORRELATES AND 

5747
03:28:47,040 --> 03:28:49,560
HEALTH IMPACTS OF MEASURED 

5748
03:28:49,560 --> 03:28:51,640
TOXICANTS AND 

5749
03:28:51,640 --> 03:28:53,120
ENDOCRINE-DISRUPTING CHEMICALS 

5750
03:28:53,120 --> 03:28:56,560
AND LOOK AT VITAMIN D 

5751
03:28:56,560 --> 03:29:02,080
ASSOCIATION WITH OVARIAN 

5752
03:29:02,080 --> 03:29:02,600
HORMO

5753
03:29:02,600 --> 03:29:03,200
HORMONES.

5754
03:29:03,200 --> 03:29:08,760
SHE RECEIVED HER M.D. AT THE 

5755
03:29:08,760 --> 03:29:10,680
UNIVERSITY OF TORONTO AND SHE IS

5756
03:29:10,680 --> 03:29:12,680
AN ADJUNCT FACULTY MEMBER AND 

5757
03:29:12,680 --> 03:29:14,480
SERVED ON THE ADVISORY COMMITTEE

5758
03:29:14,480 --> 03:29:18,040
AT NIEHS AND ALL OF US WORKING 

5759
03:29:18,040 --> 03:29:20,040
GROUP.

5760
03:29:20,040 --> 03:29:20,520
WELC

5761
03:29:20,520 --> 03:29:21,280
WELCOME, DR. HARMON.

5762
03:29:21,280 --> 03:29:21,760
>>THANK YOU.

5763
03:29:21,760 --> 03:29:26,920
LET ME SHARE MY SCREEN.

5764
03:29:26,920 --> 03:29:28,720
ARE YOU SEEING MY CORRECT SLIDE?

5765
03:29:28,720 --> 03:29:30,720
>>I AM AND I'M HEARING
YOU 

5766
03:29:30,720 --> 03:29:30,960
WELL.

5767
03:29:30,960 --> 03:29:32,320
>>THANK YOU.

5768
03:29:32,320 --> 03:29:34,320
THANK YOU FOR THAT INTRODUCTION 

5769
03:29:34,320 --> 03:29:35,400
DR. UPSON.

5770
03:29:35,400 --> 03:29:39,320
TODAY I'LL TALK ABOUT THE STUDY 

5771
03:29:39,320 --> 03:29:45,120
OF ENVIRONMENT, LIFESTYLE AND 

5772
03:29:45,120 --> 03:29:45,440
FO

5773
03:29:45,440 --> 03:29:45,720
FIBROIDS.

5774
03:29:45,720 --> 03:29:48,520
THEY'RE SMOOTH MUSCLE TUMORS OF 

5775
03:29:48,520 --> 03:29:50,880
THE UTERUS AND THIS SHOWS THEY 

5776
03:29:50,880 --> 03:29:52,880
CAN OCCUR THROUGHOUT THE 

5777
03:29:52,880 --> 03:29:54,280
MUSCULAR WALL OF THE UTERUS.

5778
03:29:54,280 --> 03:29:57,240
NOT ALL PEOPLE WITH FIBROIDS 

5779
03:29:57,240 --> 03:30:00,040
KNOW THEY HAVE THEM AND IT'S THE

5780
03:30:00,040 --> 03:30:01,360
LARGER FIBROIDS THAT BECOME 

5781
03:30:01,360 --> 03:30:03,120
SYSTEMATIC AND CAN IMPACT ALL 

5782
03:30:03,120 --> 03:30:05,480
ASPECTS OF LIFE HERE 

5783
03:30:05,480 --> 03:30:07,600
DEMONSTRATED WITH AN 

5784
03:30:07,600 --> 03:30:10,760
ILLUSTRATION FROM THE NEW YORK 

5785
03:30:10,760 --> 03:30:11,160
TIMES.

5786
03:30:11,160 --> 03:30:13,480
HEAVY MENSTRUAL BLEEDING IS 

5787
03:30:13,480 --> 03:30:15,240
COMMON AND IT CAN BE SO HEAVY 

5788
03:30:15,240 --> 03:30:16,880
THAT ANEMIA AND PAIN RESULT.

5789
03:30:16,880 --> 03:30:18,760
PAIN IS COMMON AND CAN MANIFEST 

5790
03:30:18,760 --> 03:30:20,360
IN A NUMBER OF WAYS.

5791
03:30:20,360 --> 03:30:24,600
WITH LARGE FIBROIDS PEOPLE ALSO 

5792
03:30:24,600 --> 03:30:27,240
EXPERIENCE A FEELING OF FULLNESS

5793
03:30:27,240 --> 03:30:29,560
IN THEIR ABDOMEN AND CAN PUSH ON

5794
03:30:29,560 --> 03:30:32,400
OTHER ORGANS WHICH CAN LEAD TO 

5795
03:30:32,400 --> 03:30:34,280
SYMPTOMS ON BLADDER AND BOWELS.

5796
03:30:34,280 --> 03:30:37,480
SOME PEOPLE WITH FIBROIDS MAY 

5797
03:30:37,480 --> 03:30:41,200
HAVE DIFFICULTY PREGNANT OR HAVE

5798
03:30:41,200 --> 03:30:41,560
COMPLICATIONS.

5799
03:30:41,560 --> 03:30:43,480
TREATMENT EXISTS INCLUDING 

5800
03:30:43,480 --> 03:30:45,120
MEDICATION AND INTERVENTIONS 

5801
03:30:45,120 --> 03:30:47,600
WHICH SPECIFICALLY TARGET 

5802
03:30:47,600 --> 03:30:47,840
FIBROID.

5803
03:30:47,840 --> 03:30:49,120
HOWEVER, THEY FREQUENTLY COME 

5804
03:30:49,120 --> 03:30:50,040
BACK AFTER TREATMENT.

5805
03:30:50,040 --> 03:30:57,640
THE ONLY DEFINITIVE TREATMENT IS

5806
03:30:57,640 --> 03:30:59,600
HYSTERECTOMY AND FIBROIDS ARE 

5807
03:30:59,600 --> 03:31:01,480
THE LEADING CAUSE OF 

5808
03:31:01,480 --> 03:31:02,400
HYSTERECTOMY IN THE UNITED 

5809
03:31:02,400 --> 03:31:04,440
STATES.

5810
03:31:04,440 --> 03:31:06,120
IT'S A COMMON CONDITION WITH 

5811
03:31:06,120 --> 03:31:09,200
MOST WOMEN HAVING A FIBROID BY 

5812
03:31:09,200 --> 03:31:10,560
AGE 50 HOWEVER, THERE'S A HIGHER

5813
03:31:10,560 --> 03:31:13,840
PREVALENCE AMONG BLACK WOMEN.

5814
03:31:13,840 --> 03:31:15,760
HERE'S A PLOT FROM THREE STUDIES

5815
03:31:15,760 --> 03:31:17,480
EACH IN A DIFFERENT COLOR.

5816
03:31:17,480 --> 03:31:18,800
DATA FOR AFRICAN AMERICANS IN 

5817
03:31:18,800 --> 03:31:22,160
SOLID LINES AND DATA FOR WHITES 

5818
03:31:22,160 --> 03:31:24,600
IN DASHED LINES.

5819
03:31:24,600 --> 03:31:31,680
THIS BLUE LINE HERE SHOWS 

5820
03:31:31,680 --> 03:31:33,240
AFRICAN AMERICAN HAVE A 10 YEAR 

5821
03:31:33,240 --> 03:31:35,600
EARLY ONSET AND AFRICAN AMERICAN

5822
03:31:35,600 --> 03:31:41,280
WOMEN ARE MORE LIKELY TO HAVE A 

5823
03:31:41,280 --> 03:31:42,560
FIBROID BY AGE 50 AND IT MEANS 

5824
03:31:42,560 --> 03:31:44,520
THEY HAVE A LONGER TIME TO GROW,

5825
03:31:44,520 --> 03:31:45,200
BECOME SYSTEMATIC AND REQUIRE 

5826
03:31:45,200 --> 03:31:48,280
TREATMENT.

5827
03:31:48,280 --> 03:31:49,640
NOW, THESE NUMBERS ARE SOMETIMES

5828
03:31:49,640 --> 03:31:50,760
SURPRISING TO PEOPLE WHO DON'T 

5829
03:31:50,760 --> 03:31:53,720
THINK THEY KNOW ANYONE WITH A 

5830
03:31:53,720 --> 03:31:55,200
FIBROID AND USING ULTRASOUND 

5831
03:31:55,200 --> 03:31:58,040
SCREENING WE LEARNED ALMOST 50% 

5832
03:31:58,040 --> 03:31:59,920
OF PREMENOPAUSAL WOMEN HAVE A 

5833
03:31:59,920 --> 03:32:01,520
FIBROID ON ULTRASOUND THEY DON'T

5834
03:32:01,520 --> 03:32:02,120
KNOW ABOUT.

5835
03:32:02,120 --> 03:32:05,000
SO DESPITE THE BURDEN OF 

5836
03:32:05,000 --> 03:32:05,760
DISEASE, RESEARCH AND RISK 

5837
03:32:05,760 --> 03:32:07,600
FACTORS HAS BEEN SLOW.

5838
03:32:07,600 --> 03:32:09,240
THE STRONGEST RISK FACTORS AT 

5839
03:32:09,240 --> 03:32:12,840
THE TOP OF THE SLIDE ARE MOSTLY 

5840
03:32:12,840 --> 03:32:13,200
NON-MODIFIABLE.

5841
03:32:13,200 --> 03:32:15,720
EVIDENCE FOR MODIFIABLE RISK 

5842
03:32:15,720 --> 03:32:17,560
FACTORS HAVE SHOWN WEAK 

5843
03:32:17,560 --> 03:32:18,520
ASSOCIATIONS WHICH HAVE BEEN 

5844
03:32:18,520 --> 03:32:19,240
INCONSISTENT ACROSS THE 

5845
03:32:19,240 --> 03:32:19,760
LITERATURE.

5846
03:32:19,760 --> 03:32:27,880
THE EXCEPTION IS THE USE OF 

5847
03:32:27,880 --> 03:32:28,400
DEPROPROVERA.

5848
03:32:28,400 --> 03:32:31,160
GIVEN THE COMMON CONDITION WHY 

5849
03:32:31,160 --> 03:32:32,840
DON'T WE KNOW MORE?

5850
03:32:32,840 --> 03:32:35,440
THERE'S BEEN BENCH SCIENCE ON 

5851
03:32:35,440 --> 03:32:36,600
FIBROID TISSUES AND IMPORTANT 

5852
03:32:36,600 --> 03:32:38,680
STUDIES IN LABORATORY MICE AND 

5853
03:32:38,680 --> 03:32:41,480
RATS BUT THE DATA FOR HUMANS HAS

5854
03:32:41,480 --> 03:32:42,520
LAGGED BEHIND.

5855
03:32:42,520 --> 03:32:46,320
ONE REASON WE'VE BEEN LIMITED IN

5856
03:32:46,320 --> 03:32:47,520
STUDYING FIBROIDS IS THE 

5857
03:32:47,520 --> 03:32:49,160
STANDARD FIRST-LINE APPROACH TO 

5858
03:32:49,160 --> 03:32:50,280
STUDYING CONDITIONS IS THE CASE 

5859
03:32:50,280 --> 03:32:51,080
CONTROL STUDY.

5860
03:32:51,080 --> 03:32:53,520
AND THAT APPROACH REALLY DOES 

5861
03:32:53,520 --> 03:32:55,400
NOT WORK WELL WITH A COMMON 

5862
03:32:55,400 --> 03:32:57,200
DISEASE SUCH AS FIBROIDS 

5863
03:32:57,200 --> 03:33:00,440
ESPECIALLY SINCE THERE'S NO 

5864
03:33:00,440 --> 03:33:01,280
SYSTEMATIC SCREENING.

5865
03:33:01,280 --> 03:33:03,680
WHEN YOU PICK CASES HERE IN BLUE

5866
03:33:03,680 --> 03:33:05,000
FROM DIAGNOSED WOMEN AND THEN 

5867
03:33:05,000 --> 03:33:07,720
YOU PICK NON-CASES IN GRAY FROM 

5868
03:33:07,720 --> 03:33:09,800
UNDIAGNOSED WOMEN, YOU END UP 

5869
03:33:09,800 --> 03:33:11,880
WITH A LOT OF MISCLASSIFICATION 

5870
03:33:11,880 --> 03:33:14,200
BECAUSE A LOT OF THOSE 

5871
03:33:14,200 --> 03:33:15,880
UNDIAGNOSED WOMEN ALREADY HAVE 

5872
03:33:15,880 --> 03:33:17,720
FIBROIDS HERE MARK WITH AN X AND

5873
03:33:17,720 --> 03:33:18,840
THIS LEADS TO MISCLASSIFICATION 

5874
03:33:18,840 --> 03:33:21,880
OF OUR CASES AND CONTROLS OR 

5875
03:33:21,880 --> 03:33:22,280
NON-CASES.

5876
03:33:22,280 --> 03:33:24,280
THE OTHER ISSUE THAT ARISES IN 

5877
03:33:24,280 --> 03:33:26,360
HUMAN STUDIES IS RELATED TO 

5878
03:33:26,360 --> 03:33:27,200
TIMING.

5879
03:33:27,200 --> 03:33:32,600
WE KNOW FIBROIDS START WITH 

5880
03:33:32,600 --> 03:33:34,680
ALTERATIONS TO A SINGLE CELL 

5881
03:33:34,680 --> 03:33:36,880
UNTIL IT GROWS LARGE ENOUGH TO 

5882
03:33:36,880 --> 03:33:39,160
BE SEEN AND MAY GROW LARGE TO 

5883
03:33:39,160 --> 03:33:40,680
CAUSE SYSTEMS AND MAY BE 

5884
03:33:40,680 --> 03:33:42,080
DIAGNOSED BY A CLINICIAN.

5885
03:33:42,080 --> 03:33:44,920
WHEN WE STUDY EXPOSURES IN 

5886
03:33:44,920 --> 03:33:46,120
FIBROIDS WE CAN SEE OR 

5887
03:33:46,120 --> 03:33:48,600
DIAGNOSED, WE MAY BE LOOKING AT 

5888
03:33:48,600 --> 03:33:49,720
THE WRONG TIME POINT.

5889
03:33:49,720 --> 03:33:55,000
WE WANT TO KNOW THE EXPOSURE 

5890
03:33:55,000 --> 03:33:56,760
EARLIER ON BEFORE THE FIBROID 

5891
03:33:56,760 --> 03:33:58,760
AND THIS IS MISCLASSIFICATION OF

5892
03:33:58,760 --> 03:33:59,400
OUR EXPOSURE.

5893
03:33:59,400 --> 03:34:02,800
THE EXISTING HUMAN STUD Y OF 

5894
03:34:02,800 --> 03:34:04,400
RISK FACTORS FOR FIBROIDS MOSTLY

5895
03:34:04,400 --> 03:34:07,320
DON'T HAVE THE DATA THAT ALLOW 

5896
03:34:07,320 --> 03:34:08,640
TO US LEARN WITH THE DEVELOPMENT

5897
03:34:08,640 --> 03:34:10,440
OF FIBROIDS.

5898
03:34:10,440 --> 03:34:12,440
THEY MAY MISS IMPORTANT 

5899
03:34:12,440 --> 03:34:13,840
EXPOSURES THAT MAY OCCUR BEFORE 

5900
03:34:13,840 --> 03:34:14,240
FIBROIDS DEVELOP.

5901
03:34:14,240 --> 03:34:17,440
THE EXISTING STUDIES ARE 

5902
03:34:17,440 --> 03:34:19,280
IMPORTANT BUT ISSUES WITH THE 

5903
03:34:19,280 --> 03:34:19,880
STUDY DESIGN MEANING THEY'RE 

5904
03:34:19,880 --> 03:34:21,480
HARD TO REPLICATE.

5905
03:34:21,480 --> 03:34:23,560
AND WITHOUT KNOWING THE EARLY 

5906
03:34:23,560 --> 03:34:24,200
DEVELOPMENT OR NATURAL HISTORY 

5907
03:34:24,200 --> 03:34:27,120
OF FIBROIDS IT CAN BE DIFFICULT 

5908
03:34:27,120 --> 03:34:28,080
TO IDENTIFY IMPORTANT EXPOSURES 

5909
03:34:28,080 --> 03:34:28,560
INCLUDING ENVIRONMENTAL 

5910
03:34:28,560 --> 03:34:31,120
EXPOSURES.

5911
03:34:31,120 --> 03:34:32,680
TO ADVANCE OUR KNOWLEDGE OF RISK

5912
03:34:32,680 --> 03:34:34,400
FACTORS FOR FIBROIDS WE NEED 

5913
03:34:34,400 --> 03:34:37,600
STRONG STUDY DESIGNS.

5914
03:34:37,600 --> 03:34:39,200
SO NOW I'M GOING TO TELL YOU 

5915
03:34:39,200 --> 03:34:41,560
ABOUT THE STUDY OF ENVIRONMENT, 

5916
03:34:41,560 --> 03:34:44,040
LIFESTYLE AND FIBROIDS.

5917
03:34:44,040 --> 03:34:46,440
DONNA BAIRD IS THE P.I. AND I'M 

5918
03:34:46,440 --> 03:34:49,080
THE STAFF SCIENTIST.

5919
03:34:49,080 --> 03:34:51,200
SELF-RECRUITED YOUNG BLACK OR 

5920
03:34:51,200 --> 03:34:52,160
AFRICAN AMERICAN WOMEN WHO LIVED

5921
03:34:52,160 --> 03:34:55,320
IN THE DETROIT, MICHIGAN AREA TO

5922
03:34:55,320 --> 03:34:58,480
BE PART OF THE STUDY.

5923
03:34:58,480 --> 03:35:00,120
THE CRITERIA WAS NO PRIOR 

5924
03:35:00,120 --> 03:35:01,600
DIAGNOSIS OF FIBROIDS AND HERE'S

5925
03:35:01,600 --> 03:35:02,920
OUR WONDERFUL STUDY STAFF IN 

5926
03:35:02,920 --> 03:35:07,160
NORTH CAROLINA AND AT OUR 

5927
03:35:07,160 --> 03:35:11,400
PARTNER INSTITUTION HENRY FORD 

5928
03:35:11,400 --> 03:35:12,200
HEALTH IN DETROIT.

5929
03:35:12,200 --> 03:35:18,840
SELF IS A FACE-IVE-YEAR PRODUCT 

5930
03:35:18,840 --> 03:35:19,800
STUDY.

5931
03:35:19,800 --> 03:35:21,040
SELF-HAD HIGH RETENTION.

5932
03:35:21,040 --> 03:35:23,160
WE ENROLLED JUST UNDER 1700 

5933
03:35:23,160 --> 03:35:25,680
PARTICIPANTS AND MORE THAN 90% 

5934
03:35:25,680 --> 03:35:31,600
RETURNED TO THE FIVE-YEAR VISIT.

5935
03:35:31,600 --> 03:35:36,840
EXCUSE ME, AND EVERY VISIT WE 

5936
03:35:36,840 --> 03:35:39,600
DID AN ULTRASOUND AND DID CLINIC

5937
03:35:39,600 --> 03:35:41,320
MEASURES AND BIO SPECIMEN.

5938
03:35:41,320 --> 03:35:43,360
WITH THIS STUDY DESIGN WE CAN 

5939
03:35:43,360 --> 03:35:45,120
NOW DO A NUMBER OF THINGS THAT 

5940
03:35:45,120 --> 03:35:47,480
WERE IMPOSSIBLE WITH PRIOR STUDY

5941
03:35:47,480 --> 03:35:47,720
DESIGNS.

5942
03:35:47,720 --> 03:35:51,240
WE CAN USE ULTRASOUND TO DETECT 

5943
03:35:51,240 --> 03:35:52,520
NEW FIBROIDS WHEN THEY FIRST 

5944
03:35:52,520 --> 03:35:54,600
APPEAR AND THIS ALLOWS US TO 

5945
03:35:54,600 --> 03:35:56,600
CORRECTLY IDENTIFY CASES AND 

5946
03:35:56,600 --> 03:35:56,880
NON-CASES.

5947
03:35:56,880 --> 03:35:58,480
WE CAN MEASURE THE GROWTH OF 

5948
03:35:58,480 --> 03:36:00,280
INDIVIDUAL FIBROIDS WHICH ALLOWS

5949
03:36:00,280 --> 03:36:03,120
US TO STUDY FACTORS WHICH 

5950
03:36:03,120 --> 03:36:03,680
INFLUENCE FIBROID GROWTH.

5951
03:36:03,680 --> 03:36:05,920
THIS DESIGN ALLOWS US TO MEASURE

5952
03:36:05,920 --> 03:36:08,000
EXPOSURES BEFORE THE FIBROIDS 

5953
03:36:08,000 --> 03:36:09,200
DEVELOP OR EXPOSURES THAT CHANGE

5954
03:36:09,200 --> 03:36:12,000
OVER TIME SO WE CAN MINIMIZE 

5955
03:36:12,000 --> 03:36:13,280
EXPOSURE IN THE CLASSIFICATION 

5956
03:36:13,280 --> 03:36:17,560
AND IN ADDITION TO FIBROIDS, 

5957
03:36:17,560 --> 03:36:19,640
SELF-WAS ABLE TO STUDY A WIDE 

5958
03:36:19,640 --> 03:36:22,640
RANGE OF OUTCOMES WITH LESS 

5959
03:36:22,640 --> 03:36:23,640
BIAS.

5960
03:36:23,640 --> 03:36:30,160
WHY'S THIS MATTER, KNOWING THE 

5961
03:36:30,160 --> 03:36:34,280
NATURE HISTORY AND FOR THOSE WHO

5962
03:36:34,280 --> 03:36:36,160
DEVELOP AND KNOWING WHEN WE 

5963
03:36:36,160 --> 03:36:38,640
SHOULD TREAT.

5964
03:36:38,640 --> 03:36:43,360
IF WE CAN FIND EXPOSURES WE 

5965
03:36:43,360 --> 03:36:44,960
COULD DELAY THE NEED FOR 

5966
03:36:44,960 --> 03:36:46,000
INVASIVE TREATMENTS.

5967
03:36:46,000 --> 03:36:47,920
AND IF WE IDENTIFY EXPOSURES 

5968
03:36:47,920 --> 03:36:52,600
THAT INCREASE THE RISK OF NEW 

5969
03:36:52,600 --> 03:37:00,400
FIBE FIBROIDS AND WE CAN 

5970
03:37:00,400 --> 03:37:00,920
PRIORITIZE SCREENING.

5971
03:37:00,920 --> 03:37:03,240
NOW I'LL TALK ABOUT A COUPLE OF 

5972
03:37:03,240 --> 03:37:11,800
STUDIES WE'VE DONE IN SELF.

5973
03:37:11,800 --> 03:37:18,040
AND WE LOOKED AT INFANT SOY 

5974
03:37:18,040 --> 03:37:19,920
FORMULA AND I'LL SHARE SOME OF 

5975
03:37:19,920 --> 03:37:22,320
WHAT WE LEARN ABOUT THE HISTORY 

5976
03:37:22,320 --> 03:37:23,280
OF FIBROID DEVELOPMENT.

5977
03:37:23,280 --> 03:37:24,600
BEFORE DESCRIBING THE OUTCOMES 

5978
03:37:24,600 --> 03:37:26,000
AND STATISTICAL MODELS I WANTED 

5979
03:37:26,000 --> 03:37:28,400
TO GIVE YOU A SENSE OF THE 

5980
03:37:28,400 --> 03:37:31,040
SELF-COHORT AND THE MEAN AGE WAS

5981
03:37:31,040 --> 03:37:33,040
29 YEARS AT ENROLLMENT.

5982
03:37:33,040 --> 03:37:36,320
IT HAS HIGH EDUCATIONAL 

5983
03:37:36,320 --> 03:37:37,160
ATTAINMENT AND MOST WERE 

5984
03:37:37,160 --> 03:37:39,280
CURRENCURRENT

5985
03:37:39,280 --> 03:37:42,000
LY EMPLOYED AND 45% HAD A 

5986
03:37:42,000 --> 03:37:45,080
HOUSEHOLD INCOME BELOW $20,000.

5987
03:37:45,080 --> 03:37:46,960
60% HAD HAD A BIRTH.

5988
03:37:46,960 --> 03:37:48,680
THE FIBROID OUTCOMES I'LL BE 

5989
03:37:48,680 --> 03:37:50,520
DISCUSSING ARE BASED ON 

5990
03:37:50,520 --> 03:37:52,440
CONSECUTIVE VISITS OR INTERVALS 

5991
03:37:52,440 --> 03:37:54,600
WITH AN ULTRASOUND AT EACH VISIT

5992
03:37:54,600 --> 03:37:57,680
HERE SHOWN AS A SCHEMATIC WITH A

5993
03:37:57,680 --> 03:38:01,280
LINE DRAWING OF A HUMAN UTERUS.

5994
03:38:01,280 --> 03:38:04,560
DIFFERENCES IN THE STATUS OR 

5995
03:38:04,560 --> 03:38:06,920
CHARACTERISTICS AT EACH VISIT 

5996
03:38:06,920 --> 03:38:08,040
ALLOWS US TO LOOK AT THE 

5997
03:38:08,040 --> 03:38:09,520
OUTCOMES AND I'LL SHARE THE 

5998
03:38:09,520 --> 03:38:12,600
DEVELOPMENT OF NEW FIBROIDS AND 

5999
03:38:12,600 --> 03:38:13,800
FIBROID GROWTH.

6000
03:38:13,800 --> 03:38:16,560
SO SELF-DATA HAS BEEN USED TO 

6001
03:38:16,560 --> 03:38:18,160
DESCRIBE THE NATURAL HISTORY OF 

6002
03:38:18,160 --> 03:38:21,000
FIBROIDS WHICH HAS BEEN LACKING 

6003
03:38:21,000 --> 03:38:21,320
PREVIOUSLY.

6004
03:38:21,320 --> 03:38:23,920
THIS WORK WAS CONDUCTED BY DONNA

6005
03:38:23,920 --> 03:38:25,160
BAIRD THE P.I. HERSELF.

6006
03:38:25,160 --> 03:38:27,560
WHEN LOOKING AT THE INCIDENTS OR

6007
03:38:27,560 --> 03:38:29,400
THE CHANCE A PARTICIPANT WILL 

6008
03:38:29,400 --> 03:38:31,200
DEVELOP A FIBROID BY THE END OF 

6009
03:38:31,200 --> 03:38:33,400
THE STUDY WE SEE INCREASING RISK

6010
03:38:33,400 --> 03:38:35,960
WITH AGE FROM 18% AMONG THOSE 23

6011
03:38:35,960 --> 03:38:38,400
TO 25 AT ENROLLMENT TO NEARLY 

6012
03:38:38,400 --> 03:38:41,120
30% AMONG THOSE WHO WERE 32 TO 

6013
03:38:41,120 --> 03:38:41,320
35.

6014
03:38:41,320 --> 03:38:43,480
WE'VE ALSO BEEN ABLE TO FOLLOW 

6015
03:38:43,480 --> 03:38:44,680
THE GROWTH OF INDIVIDUAL 

6016
03:38:44,680 --> 03:38:47,000
FIBROIDS IN MORE THAN 400 

6017
03:38:47,000 --> 03:38:47,360
PARTICIPANTS.

6018
03:38:47,360 --> 03:38:50,640
AVERAGE GROWTH WAS 68% FOR 18 

6019
03:38:50,640 --> 03:38:52,120
MONTHS AND FIBROID GROWTH 

6020
03:38:52,120 --> 03:38:55,320
DECLINED STEEPLY INCREASING AGE.

6021
03:38:55,320 --> 03:39:03,400
SO NOW I'M GOING TO DISCUSS DMPA

6022
03:39:03,400 --> 03:39:06,560
A PROGESTERONE ONLY FORM OF 

6023
03:39:06,560 --> 03:39:08,200
CONTRACEPTION GIVEN AS AN 

6024
03:39:08,200 --> 03:39:11,040
INTRAMUSCULAR SHOT EVERY THREE 

6025
03:39:11,040 --> 03:39:11,520
MONTHS.

6026
03:39:11,520 --> 03:39:14,840
THREE PREVIOUS STUDIES INCLUDING

6027
03:39:14,840 --> 03:39:20,360
CROSS-SECTIONAL ANALYSIS HAVE 

6028
03:39:20,360 --> 03:39:21,600
SHOWN PROTECTIVE AGENTS FOR 

6029
03:39:21,600 --> 03:39:24,080
FIBROIDS WITH ESTIMATED RELATIVE

6030
03:39:24,080 --> 03:39:26,640
RISK BELOW THE NUL VALUE OF 1.

6031
03:39:26,640 --> 03:39:29,080
HOWEVER, THE STUDIES HAVE A 

6032
03:39:29,080 --> 03:39:31,960
NUMBER OF APPLIES BASED ON 

6033
03:39:31,960 --> 03:39:32,320
DESIGN.

6034
03:39:32,320 --> 03:39:36,560
WE EXPLORED THE HYPOTHESIS WITH 

6035
03:39:36,560 --> 03:39:38,960
OUR PROSPECTIVE DESIGN WITH 

6036
03:39:38,960 --> 03:39:39,200
SCREENING.

6037
03:39:39,200 --> 03:39:41,360
WE LOOKED AT SELF-REPORTED USE 

6038
03:39:41,360 --> 03:39:44,840
OF DMPA WITH ANY CHANGES AT USE 

6039
03:39:44,840 --> 03:39:48,600
AT ANY FOLLOW-UP SHIFT TO 

6040
03:39:48,600 --> 03:39:51,880
ESTIMATE THE TIME LAST USED OF 

6041
03:39:51,880 --> 03:39:52,680
DMPA.

6042
03:39:52,680 --> 03:39:55,080
40% HAD EVER USED DMPA.

6043
03:39:55,080 --> 03:39:57,520
FOR OUR STATISTICAL ANALYSES AND

6044
03:39:57,520 --> 03:40:00,280
OTHER EXPOSURES WE USED THE SAME

6045
03:40:00,280 --> 03:40:02,000
INTERVALS I DESCRIBED EARLIER 

6046
03:40:02,000 --> 03:40:03,480
AND EACH PARTICIPANT COULD HAVE 

6047
03:40:03,480 --> 03:40:08,400
UP TO THREE OBSERVED INTERVALS.

6048
03:40:08,400 --> 03:40:10,840
WE USED SEPARATE STATISTICAL 

6049
03:40:10,840 --> 03:40:11,680
MODELS.

6050
03:40:11,680 --> 03:40:12,600
HOWEVER, EXPOSURES AND 

6051
03:40:12,600 --> 03:40:14,280
COVARIATES ARE UPDATED AT EVERY 

6052
03:40:14,280 --> 03:40:16,400
VISIT AND ALL MODELS ACCOUNTED 

6053
03:40:16,400 --> 03:40:18,680
FOR REPEATED MEASURES AT THE 

6054
03:40:18,680 --> 03:40:24,480
LEVEL OF PARTICIPANT OR FIBROID 

6055
03:40:24,480 --> 03:40:25,800
AND FOLLOWING INTERVENTION TO 

6056
03:40:25,800 --> 03:40:26,760
TREAT FIBROIDS.

6057
03:40:26,760 --> 03:40:29,120
THE FIRST INCOME IS INCIDENT 

6058
03:40:29,120 --> 03:40:31,240
FIBROIDS DEFINED AS A NEW 

6059
03:40:31,240 --> 03:40:32,680
FIBROID CASE AMONG PARTICIPANTS 

6060
03:40:32,680 --> 03:40:35,720
WITH NO PRIOR FIBROIDS OBSERVED 

6061
03:40:35,720 --> 03:40:37,280
IN THE STUDY AND WE USED THE 

6062
03:40:37,280 --> 03:40:38,760
TIME SCALE TO ESTIMATE THE 

6063
03:40:38,760 --> 03:40:40,560
ADJUSTED HAZARD RATIOS.

6064
03:40:40,560 --> 03:40:44,560
ON TO THE RESULTS FOR INCIDENT 

6065
03:40:44,560 --> 03:40:46,520
SHOWING THE HAZARD RATIO.

6066
03:40:46,520 --> 03:40:49,080
THE NUL VALUE OF NO ASSOCIATION 

6067
03:40:49,080 --> 03:40:50,880
IS 1 SHOWN WITH THE VERTICAL 

6068
03:40:50,880 --> 03:40:55,120
LINE, VALUES ABOVE 1 REPRESENT 

6069
03:40:55,120 --> 03:40:57,360
AN INCREASED RISK AND VALUES 

6070
03:40:57,360 --> 03:40:59,920
LESS THAN 1 ARE A NEGATIVE OR 

6071
03:40:59,920 --> 03:41:00,440
PROTECTIVE ASSOCIATION.

6072
03:41:00,440 --> 03:41:02,920
AND THE COMPARISON GROUP IS 

6073
03:41:02,920 --> 03:41:06,080
NEVER USED DMPA SHOWN BY THE 

6074
03:41:06,080 --> 03:41:07,120
BLACK DOT AT THE NUL.

6075
03:41:07,120 --> 03:41:10,160
FOR INCIDENT FIBROIDS WE SEE OF 

6076
03:41:10,160 --> 03:41:11,800
DMPA WITHIN TWO YEARS IS 

6077
03:41:11,800 --> 03:41:14,200
ASSOCIATED WITH A 40% REDUCTION 

6078
03:41:14,200 --> 03:41:16,560
IN FIBROID INCIDENTS WITH A 

6079
03:41:16,560 --> 03:41:19,000
HAZARD RATIO OF 0.6 AS SHOWN BY 

6080
03:41:19,000 --> 03:41:21,240
THE DOT AND THEN THE HORIZONTAL 

6081
03:41:21,240 --> 03:41:24,600
LINE CAPTURES THE 95% CONFIDENCE

6082
03:41:24,600 --> 03:41:27,040
INTERVAL.

6083
03:41:27,040 --> 03:41:28,560
FIBROID GROWTH IS THE OTHER 

6084
03:41:28,560 --> 03:41:30,200
OUTCOME WE STUDY AND GROWTH WAS 

6085
03:41:30,200 --> 03:41:32,600
DEFINED AS A CHANGE IN VOLUME 

6086
03:41:32,600 --> 03:41:34,400
BETWEEN VISITS AND TO ACCOUNT 

6087
03:41:34,400 --> 03:41:36,240
FOR DIFFERENCE IN TIME BETWEEN 

6088
03:41:36,240 --> 03:41:38,160
VISITS WE SCALE OUR OUTCOMES TO 

6089
03:41:38,160 --> 03:41:41,400
18 MONTHS AND THIS ANALYSIS USED

6090
03:41:41,400 --> 03:41:44,720
FIBROIDS WHICH CAN BE MATCHED 

6091
03:41:44,720 --> 03:41:46,200
AND A PARTICIPANT CAN HAVE 

6092
03:41:46,200 --> 03:41:48,120
MULTIPLE MATCHED FIBROIDS.

6093
03:41:48,120 --> 03:41:53,520
WE USED LINEAR MIXED MODELS.

6094
03:41:53,520 --> 03:41:55,400
THESE ARE THE RESULTS FOR 

6095
03:41:55,400 --> 03:41:57,000
FIBROID GROWTH AND I'M 

6096
03:41:57,000 --> 03:41:59,080
ESTIMATING THE RELATIVE BIRTH 

6097
03:41:59,080 --> 03:42:00,640
RATE OVER 18 MONTHS COMPARED 

6098
03:42:00,640 --> 03:42:02,760
EXPOSED TO NEVER USERS.

6099
03:42:02,760 --> 03:42:04,600
WE SEE A STRONG ASSOCIATION FOR 

6100
03:42:04,600 --> 03:42:05,680
REDUCED GROWTH FOR THOSE WHO 

6101
03:42:05,680 --> 03:42:08,920
USED DMPA WITHIN TWO YEARS OF A 

6102
03:42:08,920 --> 03:42:10,280
VISIT.

6103
03:42:10,280 --> 03:42:11,800
THE AVERAGE GROWTH RATE AMONG 

6104
03:42:11,800 --> 03:42:17,680
THIS IS ABOUT 45% LOWER COMPARED

6105
03:42:17,680 --> 03:42:20,120
TO -- SO IN SUMMARY THOSE 

6106
03:42:20,120 --> 03:42:22,440
EXPOSED TO DMPA WITHIN TWO YEARS

6107
03:42:22,440 --> 03:42:26,080
OF A VISIT HAVE A 40% REDUCTION 

6108
03:42:26,080 --> 03:42:29,640
IN FIBROID INDENTS AND A 45% 

6109
03:42:29,640 --> 03:42:30,640
REDUCTION IN FIBROID GROWTH.

6110
03:42:30,640 --> 03:42:32,160
AND THOUGH I DIDN'T SHOW THIS 

6111
03:42:32,160 --> 03:42:33,720
RESULT, THIS REDUCTION IN GROWTH

6112
03:42:33,720 --> 03:42:36,600
IS RESULTING IN FIBROID 

6113
03:42:36,600 --> 03:42:38,480
SHRINKAGE AND THE RECENT USERS 

6114
03:42:38,480 --> 03:42:42,480
OF DMPA, 70% WERE MORE LIKELY TO

6115
03:42:42,480 --> 03:42:44,240
LOSE A FIBROID BETWEEN VISITS 

6116
03:42:44,240 --> 03:42:45,120
DUE TO THE LOWER GROWTH.

6117
03:42:45,120 --> 03:42:47,480
THESE RESULTS POINT TO AN 

6118
03:42:47,480 --> 03:42:49,120
IMPORTANT NON-CONTRACEPTIVE 

6119
03:42:49,120 --> 03:42:52,160
BENEFIT OF DMPA WHICH HAS THE 

6120
03:42:52,160 --> 03:42:52,960
POTENTIAL TO DELAY SYMPTOMS AND 

6121
03:42:52,960 --> 03:42:55,160
THE NEED FOR INVASIVE TREATMENTS

6122
03:42:55,160 --> 03:42:56,600
HOWEVER, THE ASSOCIATIONS NEED 

6123
03:42:56,600 --> 03:42:57,280
TO BE REPLICATED IN LARGER 

6124
03:42:57,280 --> 03:43:02,640
POPULATIONS.

6125
03:43:02,640 --> 03:43:04,640
I'M NOW GOING TO DISCUSS SOY 

6126
03:43:04,640 --> 03:43:07,240
INFANT FORMULA AND THE WORK WAS 

6127
03:43:07,240 --> 03:43:09,840
DONE BY A POST-DOCTORAL FELLOW 

6128
03:43:09,840 --> 03:43:11,280
IN OUR GROUP.

6129
03:43:11,280 --> 03:43:13,160
MANY PLANT HAVE PHYTO ESTROGENS 

6130
03:43:13,160 --> 03:43:18,920
AND A TYPE THAT ARE FOUND IN 

6131
03:43:18,920 --> 03:43:23,160
LEGUMES AND SOYBEANS IN SIMILAR 

6132
03:43:23,160 --> 03:43:24,960
STRUCTURE TO ESTRADIOL.

6133
03:43:24,960 --> 03:43:27,280
IT CAN BIND TO THE ESTROGEN 

6134
03:43:27,280 --> 03:43:35,600
RECEPTOR AND WHILE ISOFLAVONES 

6135
03:43:35,600 --> 03:43:39,520
CAN ACT AS AN ENDOCRINE 

6136
03:43:39,520 --> 03:43:40,080
DISRUPTOR.

6137
03:43:40,080 --> 03:43:41,840
EARLY LIFE EXPOSURE CAN ALTER 

6138
03:43:41,840 --> 03:43:44,600
THE REPRODUCTIVE TRACT OF MICE 

6139
03:43:44,600 --> 03:43:48,360
AND A RAT MODEL HAS IDENTIFIED 

6140
03:43:48,360 --> 03:43:49,600
AN EPIDEMIOLOGIC PATHWAY BY 

6141
03:43:49,600 --> 03:43:51,240
WHICH EARLY LIFE EXPOSURE LED TO

6142
03:43:51,240 --> 03:43:53,080
FIBROID DEVELOPMENT IN ADULT 

6143
03:43:53,080 --> 03:43:53,560
RATS.

6144
03:43:53,560 --> 03:43:56,160
IT'S BEEN HYPOTHESIZED EXPOSURE 

6145
03:43:56,160 --> 03:43:57,760
TO ESTROGEN LIKE COMPONENTS SUCH

6146
03:43:57,760 --> 03:44:00,600
AS SOY FORMULA DURING SENSITIVE 

6147
03:44:00,600 --> 03:44:02,720
DEVELOPMENT WINDOWS MAY BEING 

6148
03:44:02,720 --> 03:44:06,080
DETRIMENTAL TO THE DEVELOPING 

6149
03:44:06,080 --> 03:44:08,160
REPRODUCTIVE TRACT INCLUDING THE

6150
03:44:08,160 --> 03:44:08,880
UTERUS.

6151
03:44:08,880 --> 03:44:13,200
SOY FORMULA IS CONSUMED BY ABOUT

6152
03:44:13,200 --> 03:44:17,480
12% INFANTS AND CONTAINS PHYTO 

6153
03:44:17,480 --> 03:44:19,680
ESTROGENS AND WHEN IT'S THE ONLY

6154
03:44:19,680 --> 03:44:21,680
FOOD CONSUMED IT'S QUITE HIGH 

6155
03:44:21,680 --> 03:44:24,320
AND SOY FORMULA FEEDING HAS BEEN

6156
03:44:24,320 --> 03:44:27,120
LINKED TO SEVERAL FEMALE 

6157
03:44:27,120 --> 03:44:28,240
REPRODUCTIVE CONDITIONS 

6158
03:44:28,240 --> 03:44:28,760
INCLUDING ENDOMETRIOSIS 

6159
03:44:28,760 --> 03:44:29,880
DESCRIBED EARLIER BY DR. UPSON.

6160
03:44:29,880 --> 03:44:33,360
AND IN A HUMAN STUDY THAT 

6161
03:44:33,360 --> 03:44:36,120
DEVELOPED THE DEVELOPMENT OF 

6162
03:44:36,120 --> 03:44:37,800
ESTROGEN RECEPTIVE TISSUE IN 

6163
03:44:37,800 --> 03:44:44,400
INFA

6164
03:44:44,400 --> 03:44:47,560
INFANTS, INFANTS HAD VAGINAL 

6165
03:44:47,560 --> 03:44:48,880
CELL CHANGES IN THE LINING 

6166
03:44:48,880 --> 03:44:50,880
RATHER THAN THOSE WITH COW 

6167
03:44:50,880 --> 03:44:51,840
FORMULA.

6168
03:44:51,840 --> 03:44:55,640
WE GAVE A QUESTIONNAIRE STYLED 

6169
03:44:55,640 --> 03:44:57,560
AS AN INTERVIEW AND 90% OF 

6170
03:44:57,560 --> 03:44:59,120
PARTICIPANTS WERE ABLE TO 

6171
03:44:59,120 --> 03:45:03,160
INTERVIEW THEIR MOTHERS AND 11% 

6172
03:45:03,160 --> 03:45:06,840
TALKED TO RELATIVES OR OTHERS 

6173
03:45:06,840 --> 03:45:10,600
INVOLVED IN THEIR INFANCY AND 

6174
03:45:10,600 --> 03:45:12,800
HOW SOON THEY WERE SAID FORMULA 

6175
03:45:12,800 --> 03:45:15,000
AND HOW MUCH AND WE CREATED A 

6176
03:45:15,000 --> 03:45:16,360
VARIABLE WHERE PARTICIPANT 

6177
03:45:16,360 --> 03:45:17,600
CHARACTERIZED WITH HIGHLY 

6178
03:45:17,600 --> 03:45:19,280
EXPOSED, IF THEY WERE FED SOY 

6179
03:45:19,280 --> 03:45:20,280
FORMULA IN THE FIRST TWO MONTHS 

6180
03:45:20,280 --> 03:45:21,680
OF LIFE AND FOR A DURATION OF 

6181
03:45:21,680 --> 03:45:25,320
FOUR MONTHS OR LONGER.

6182
03:45:25,320 --> 03:45:27,360
AND HERE ARE THE ADJUSTED HAZARD

6183
03:45:27,360 --> 03:45:30,120
RATIOS FOR FIBROID INCIDENTS.

6184
03:45:30,120 --> 03:45:32,120
WE'RE COMPARING THOSE FED SOY 

6185
03:45:32,120 --> 03:45:33,520
FORMULA TO THOSE WHO NEVER 

6186
03:45:33,520 --> 03:45:34,880
RECEIVED IT AND FIND 

6187
03:45:34,880 --> 03:45:35,960
PARTICIPANTS WHO HAD SOY FORMULA

6188
03:45:35,960 --> 03:45:39,280
FEEDING WITHIN THE FIRST TWO 

6189
03:45:39,280 --> 03:45:44,960
MONTHS OF LIFE HAD A 58% 

6190
03:45:44,960 --> 03:45:47,400
INCREASE RISK OF INCIDENT 

6191
03:45:47,400 --> 03:45:48,880
FIBROIDS.

6192
03:45:48,880 --> 03:45:50,880
IN THE STUDY WE OBSERVED IT WAS 

6193
03:45:50,880 --> 03:45:56,480
ASSOCIATED WITH AN INCREASED 

6194
03:45:56,480 --> 03:46:00,600
RISK OF ALL  ULTRASOUND 

6195
03:46:00,600 --> 03:46:03,320
IDENTIFIED FIBROIDS FOR THOSE 

6196
03:46:03,320 --> 03:46:05,640
FED SOY FORMULA AFTER BIRTH AND 

6197
03:46:05,640 --> 03:46:07,120
THIS IS CONSISTENT WITH 

6198
03:46:07,120 --> 03:46:07,400
FINDINGS.

6199
03:46:07,400 --> 03:46:09,320
THEY NEED TO BE REPLICATED IN 

6200
03:46:09,320 --> 03:46:10,680
OTHER POPULATIONS AN POINT TO 

6201
03:46:10,680 --> 03:46:13,240
THE NEED TO STUDY SOY INFANT 

6202
03:46:13,240 --> 03:46:15,280
FORMULA AND OTHER ESTROGEN 

6203
03:46:15,280 --> 03:46:15,760
SENSITIVE OUTCOMES.

6204
03:46:15,760 --> 03:46:20,040
SO FINALLY, THERE'S BEEN 

6205
03:46:20,040 --> 03:46:21,120
CONSISTENT EPIDEMIOLOGIC 

6206
03:46:21,120 --> 03:46:22,400
EVIDENCE THAT THOSE WITH A BIRTH

6207
03:46:22,400 --> 03:46:24,640
ARE LESS LIKELY TO HAVE 

6208
03:46:24,640 --> 03:46:25,320
FIBROIDS.

6209
03:46:25,320 --> 03:46:27,280
THIS ASSOCIATION IS DUE TO 

6210
03:46:27,280 --> 03:46:28,560
POSTPARTUM CHANGES IN THE 

6211
03:46:28,560 --> 03:46:28,800
UTERUS.

6212
03:46:28,800 --> 03:46:30,480
IN SELF WE'VE BEEN ABLE TO ADD 

6213
03:46:30,480 --> 03:46:32,400
TO THE UNDERSTANDING OF THIS 

6214
03:46:32,400 --> 03:46:34,000
ASSOCIATION BY LOOKING AT LIFE 

6215
03:46:34,000 --> 03:46:36,600
TIME REPRODUCTIVE HISTORIES AND 

6216
03:46:36,600 --> 03:46:39,240
BY EXAMINING ASSOCIATIONS WITH 

6217
03:46:39,240 --> 03:46:40,840
SPECIFIC PREGNANCY 

6218
03:46:40,840 --> 03:46:41,240
CHARACTERISTICS.

6219
03:46:41,240 --> 03:46:43,320
WE'RE STILL ANALYZING THE DATA 

6220
03:46:43,320 --> 03:46:44,680
BUT AMONG THE FIRST TO BE ABLE 

6221
03:46:44,680 --> 03:46:46,560
TO LOOK AT THE ASSOCIATION 

6222
03:46:46,560 --> 03:46:48,320
BETWEEN BIRTH AND FIBROID 

6223
03:46:48,320 --> 03:46:48,680
GROWTH.

6224
03:46:48,680 --> 03:46:50,640
AND HERE WE FIND THAT A BIRTH 

6225
03:46:50,640 --> 03:46:52,600
WITHIN FIVE YEARS OF A VISIT 

6226
03:46:52,600 --> 03:46:54,640
RESULTS IN ABOUT A 30% REDUCTION

6227
03:46:54,640 --> 03:46:57,040
IN FIBROID GROWTH AND THE 

6228
03:46:57,040 --> 03:46:59,440
AFFECTS APPEAR TO BE STRONGER IF

6229
03:46:59,440 --> 03:47:00,640
THERE WAS BREAST FEEDING MORE 

6230
03:47:00,640 --> 03:47:02,520
THAN SIX MONTHS FOLLOWING THE 

6231
03:47:02,520 --> 03:47:02,840
BIRTH.

6232
03:47:02,840 --> 03:47:04,280
UNDERSTANDING THE STRONG 

6233
03:47:04,280 --> 03:47:04,880
ASSOCIATIONS HAVE BEEN VERY 

6234
03:47:04,880 --> 03:47:08,640
IMPORTANT IN OUR ABILITY TO 

6235
03:47:08,640 --> 03:47:10,880
ANALYZE OTHER EXPOSURES.

6236
03:47:10,880 --> 03:47:12,600
SELF HAS MANY OTHER EXPOSURES 

6237
03:47:12,600 --> 03:47:13,560
AND OUTCOMES WE'RE INVESTIGATING

6238
03:47:13,560 --> 03:47:15,040
AND HERE'S SOME OF THEM.

6239
03:47:15,040 --> 03:47:17,240
IN PARTICULAR, WE HAVE A NUMBER 

6240
03:47:17,240 --> 03:47:19,080
OF ONGOING PROJECTS EXAMINING 

6241
03:47:19,080 --> 03:47:21,280
THE USE OF PERSONAL CARE 

6242
03:47:21,280 --> 03:47:22,440
PRODUCTS, SLEEP QUALITY AND 

6243
03:47:22,440 --> 03:47:24,040
EARLY LIFE EXPOSURES.

6244
03:47:24,040 --> 03:47:27,840
WE'RE ALSO MEASURING SPECIFIC 

6245
03:47:27,840 --> 03:47:32,640
EXPOSURES IN BLOOD OR URINE AND 

6246
03:47:32,640 --> 03:47:35,440
OTHER ENDOCRINE DISRUPTING 

6247
03:47:35,440 --> 03:47:37,800
CHEMICALS AND STARTED LOOKING AT

6248
03:47:37,800 --> 03:47:38,600
VITAMIN D.

6249
03:47:38,600 --> 03:47:42,240
I HOPE I'VE GIVEN A SENSE AS 

6250
03:47:42,240 --> 03:47:43,280
STUDIES SUCH AS SELF CAN ADVANCE

6251
03:47:43,280 --> 03:47:45,720
SCIENCE IN WOMEN'S HEALTH AND 

6252
03:47:45,720 --> 03:47:48,120
OUR DESIGN AND COHORT AND 

6253
03:47:48,120 --> 03:47:48,920
COLLABORATIVE RESEARCH CAN SERVE

6254
03:47:48,920 --> 03:47:50,760
AS A MODEL FOR SIMILAR STUDIES 

6255
03:47:50,760 --> 03:47:51,960
OF OTHER OUTCOMES.

6256
03:47:51,960 --> 03:47:54,680
WE'VE RECENTLY BEGAN EXPANDING 

6257
03:47:54,680 --> 03:47:57,280
THE EXPOSURES IN OUR COHORT BY 

6258
03:47:57,280 --> 03:48:00,280
USING GEOCODING TO LOOK AT 

6259
03:48:00,280 --> 03:48:04,640
FACTORS, PROXIMITY TO TOXIC 

6260
03:48:04,640 --> 03:48:07,520
CONTAMINATION SITES AND OTHER S.

6261
03:48:07,520 --> 03:48:09,760
BUT SELF IS A SMALL BEGINNING.

6262
03:48:09,760 --> 03:48:13,720
THERE'S NO PROSPECTIVE DATA FOR 

6263
03:48:13,720 --> 03:48:16,600
HISPANICS, ASIAN AMERICANS OR 

6264
03:48:16,600 --> 03:48:19,400
AND IT NEEDS TO BE REPLICATED IN

6265
03:48:19,400 --> 03:48:22,400
OTHER POPULATIONS WITH SIMILAR 

6266
03:48:22,400 --> 03:48:22,880
DESIGNS.

6267
03:48:22,880 --> 03:48:24,640
FIBROIDS ALSO SERVE AS AN 

6268
03:48:24,640 --> 03:48:27,880
EXAMPLE OF A LIFE COURSE DISEASE

6269
03:48:27,880 --> 03:48:29,600
AND LONG-TERM INVESTMENT WILL 

6270
03:48:29,600 --> 03:48:31,320
PROVIDE OPPORTUNITIES FOR MORE 

6271
03:48:31,320 --> 03:48:32,000
INNOVATIVE SCIENCE.

6272
03:48:32,000 --> 03:48:35,440
THE WORK IN SELF IS ONLY 

6273
03:48:35,440 --> 03:48:39,160
POSSIBLE DUE TO INTRAMURAL 

6274
03:48:39,160 --> 03:48:47,640
FUNDING FROM THE NIH AND 

6275
03:48:47,640 --> 03:48:50,840
COLLABORATION BETWEEN NIE HS AND

6276
03:48:50,840 --> 03:48:56,960
SOME COLLABORATORS SOME OF WHOM 

6277
03:48:56,960 --> 03:48:58,360
ARE PICTURED HERE.

6278
03:48:58,360 --> 03:48:59,160
WITH THAT I'LL TAKE A LITTLE BIT

6279
03:48:59,160 --> 03:49:01,320
OF TIME FOR QUESTIONS.

6280
03:49:01,320 --> 03:49:02,000
>>THANK YOU.

6281
03:49:02,000 --> 03:49:03,200
WE HAVE A FEW MINUTES FOR 

6282
03:49:03,200 --> 03:49:08,600
QUESTION ABOUT DR. HARMON'S 

6283
03:49:08,600 --> 03:49:18,880
PRESENTATION.

6284
03:49:19,520 --> 03:49:23,920
>>I SEE A HAND RAISED BY 

6285
03:49:23,920 --> 03:49:24,640
DR. ROBINSON.

6286
03:49:24,640 --> 03:49:27,240
WE ALL KNOW SOMEONE WHO HAS 

6287
03:49:27,240 --> 03:49:28,520
FIBROIDS.

6288
03:49:28,520 --> 03:49:29,960
IS THERE TALK OF PARALLEL 

6289
03:49:29,960 --> 03:49:31,520
STUDIES IN OTHER PARTS AND I'VE 

6290
03:49:31,520 --> 03:49:32,960
SEEN IT SUCCESSFUL FOR OTHER 

6291
03:49:32,960 --> 03:49:34,360
DISEASES WHERE YOU HAVE THE SAME

6292
03:49:34,360 --> 03:49:38,280
EXACT STUDY AND TYPE OF COHORTS 

6293
03:49:38,280 --> 03:49:39,200
THAT YOU'RE IDENTIFYING AND 

6294
03:49:39,200 --> 03:49:40,600
LOOKING AT THE RESULTS ACROSS 

6295
03:49:40,600 --> 03:49:43,800
THE DIFFERENT GROUPS.

6296
03:49:43,800 --> 03:49:46,080
>>THE ONLY ONE I'M AWARE
OF IS 

6297
03:49:46,080 --> 03:49:49,080
A STUDY DONE BY DR. ERICA MARSH 

6298
03:49:49,080 --> 03:49:52,160
LOOKING AT HISPANIC WOMEN WITH A

6299
03:49:52,160 --> 03:49:53,480
SIMILAR PROTOCOL BUT I'M NOT 

6300
03:49:53,480 --> 03:49:55,920
AWARE OF FUNDING TO LOOK AT 

6301
03:49:55,920 --> 03:49:56,520
SIMILAR STUDIES IN OTHER 

6302
03:49:56,520 --> 03:49:57,120
POPULATIONS AROUND THE UNITED 

6303
03:49:57,120 --> 03:50:02,680
STATES.

6304
03:50:02,680 --> 03:50:05,920
I WILL NOTE THIS WAS FUNDED 

6305
03:50:05,920 --> 03:50:06,240
INTRAMURALLY.

6306
03:50:06,240 --> 03:50:07,040
>>OKAY.

6307
03:50:07,040 --> 03:50:10,080
>>SOME OF THIS WORK
ESPECIALLY 

6308
03:50:10,080 --> 03:50:11,560
WORK ON THE NATURAL HISTORY OF 

6309
03:50:11,560 --> 03:50:14,080
COMMON DISEASES IS VERY HARD IN 

6310
03:50:14,080 --> 03:50:15,760
MY EXPERIENCE TO GET FUNDED 

6311
03:50:15,760 --> 03:50:16,080
EXTRAMURALLY.

6312
03:50:16,080 --> 03:50:18,360
AND THAT IS ONE OF THE STRENGTHS

6313
03:50:18,360 --> 03:50:28,760
OF INTRAMURAL RESEARCH.

6314
03:50:40,320 --> 03:50:44,600
>>IN BOTH STUDIES WE
HEARD 

6315
03:50:44,600 --> 03:50:46,760
EXCELLENT DESIGNS AND STRONG 

6316
03:50:46,760 --> 03:50:47,880
STUDY DESIGNS AND ANALYSIS AND I

6317
03:50:47,880 --> 03:50:48,400
APPRECIATE THAT.

6318
03:50:48,400 --> 03:50:50,080
I'M WONDERING HOW TO TAKE IT TO 

6319
03:50:50,080 --> 03:50:52,400
THE NEXT LEVEL AND PARTICULARLY 

6320
03:50:52,400 --> 03:50:54,080
I WAS WONDERING IF THERE'S AN 

6321
03:50:54,080 --> 03:50:56,920
OPPORTUNITY TO BUILD INTO ALL OF

6322
03:50:56,920 --> 03:50:57,120
US?

6323
03:50:57,120 --> 03:51:03,440
I HAVEN'T TRACKED THE ALL OF US 

6324
03:51:03,440 --> 03:51:08,640
COHORT THAT WELL IS THERE A 

6325
03:51:08,640 --> 03:51:11,880
CHANCE TO ADD TO THE PROTOCOL TO

6326
03:51:11,880 --> 03:51:14,680
FILL OUT THE EXPOSOME ON ISSUES 

6327
03:51:14,680 --> 03:51:15,800
RELATED TO WOMEN'S HEALTH?

6328
03:51:15,800 --> 03:51:26,360
>>ALL OF US IS RECRUITING
WOMEN

6329
03:51:26,840 --> 03:51:28,120
UNFORTUNATELY THINGS LIKE 

6330
03:51:28,120 --> 03:51:32,080
FIBROIDS IS HARD TO STUDY WHICH 

6331
03:51:32,080 --> 03:51:35,200
IS WHAT WE'RE WE LYING ON FOR 

6332
03:51:35,200 --> 03:51:39,000
HEALTH OUTCOMES AND SOME CAN BE 

6333
03:51:39,000 --> 03:51:39,800
STUDYING ELECTRONIC HEALTH 

6334
03:51:39,800 --> 03:51:40,040
RECORD.

6335
03:51:40,040 --> 03:51:42,080
FIBROID NOT ONE OF THEM.

6336
03:51:42,080 --> 03:51:44,800
THERE'S THE POTENTIAL TO DO 

6337
03:51:44,800 --> 03:51:47,080
SUBSTUDIES WITHIN ALL OF US.

6338
03:51:47,080 --> 03:51:49,720
AND I THINK IT WOULD BE GOOD FOR

6339
03:51:49,720 --> 03:51:52,960
OUTCOMES WHERE E.H.R. IS A GOOD 

6340
03:51:52,960 --> 03:51:57,600
SOURCE OF MEASURING YOUR 

6341
03:51:57,600 --> 03:51:57,840
OUTCOME.

6342
03:51:57,840 --> 03:51:59,680
>>AN SOMEONE ANSWER A
STUDY TO 

6343
03:51:59,680 --> 03:52:02,240
THAT TO BE TAKEN A SUBSET OF 

6344
03:52:02,240 --> 03:52:04,440
1,000 WOMEN AND DOING 

6345
03:52:04,440 --> 03:52:04,720
ULTRASOUNDS?

6346
03:52:04,720 --> 03:52:08,600
>>I THINK ALL OF US IS IN
THE 

6347
03:52:08,600 --> 03:52:12,920
PROCESS OF BUILDING OUT THEIR 

6348
03:52:12,920 --> 03:52:15,320
CAPACITY TO DEFINE AND DEAL WITH

6349
03:52:15,320 --> 03:52:16,600
ANCILLARY STUDIES.

6350
03:52:16,600 --> 03:52:18,160
>>OKAY.

6351
03:52:18,160 --> 03:52:20,080
>>THEY DO HAVE A
RESEARCHER 

6352
03:52:20,080 --> 03:52:21,760
WORK BENCH THAT ALLOWS 

6353
03:52:21,760 --> 03:52:25,120
RESEARCHERS TO ACCESS THE 

6354
03:52:25,120 --> 03:52:27,080
EXISTING DATA NOT NECESSARILY DO

6355
03:52:27,080 --> 03:52:28,920
ADDITIONAL WORK WITH A SUBCOHORT

6356
03:52:28,920 --> 03:52:33,240
BUT THERE IS A DASHBOARD WHERE 

6357
03:52:33,240 --> 03:52:34,840
PEOPLE CAN ACCESS EXISTING DATA.

6358
03:52:34,840 --> 03:52:35,720
>>GREAT.

6359
03:52:35,720 --> 03:52:37,680
THANK YOU SO MUCH, DR. HARMON.

6360
03:52:37,680 --> 03:52:40,280
I THINK I WOULD LIKE TO NOW 

6361
03:52:40,280 --> 03:52:43,520
INTRODUCE OUR FINAL PANELIST, 

6362
03:52:43,520 --> 03:52:44,520
DR. DALE SANDLER.

6363
03:52:44,520 --> 03:52:48,040
HE IS A SENIOR INVESTIGATOR AND 

6364
03:52:48,040 --> 03:52:48,920
CHIEF OF THE EPIDEMIOLOGY BRANCH

6365
03:52:48,920 --> 03:52:50,600
IN THE INTRAMURAL RESEARCH 

6366
03:52:50,600 --> 03:52:51,320
PROGRAM OF THE NATIONAL 

6367
03:52:51,320 --> 03:52:55,440
INSTITUTE OF ENVIRONMENTAL 

6368
03:52:55,440 --> 03:52:58,200
HEALTH SCIENCES, WHERE SHE LEADS

6369
03:52:58,200 --> 03:53:00,120
THE CHRONIC DISEASE EPIDEMIOLOGY

6370
03:53:00,120 --> 03:53:03,080
GROUP AND RECEIVED HER B.A. FROM

6371
03:53:03,080 --> 03:53:05,040
BOSTON UNIVERSITY AND Ph.D. FROM

6372
03:53:05,040 --> 03:53:07,200
YALE UNIVERSITY AND Ph.D. IN 

6373
03:53:07,200 --> 03:53:08,680
EPIDEMIOLOGY FROM JOHNS HOPKINS 

6374
03:53:08,680 --> 03:53:09,000
UNIVERSITY.

6375
03:53:09,000 --> 03:53:11,000
SHE IS PRINCIPLE INVESTIGATOR OF

6376
03:53:11,000 --> 03:53:13,080
THE SISTER STUDY.

6377
03:53:13,080 --> 03:53:15,880
A U.S.-WIDE COHORT OF OVER 

6378
03:53:15,880 --> 03:53:17,960
50,000 WOMAN WHO HAD A SISTER 

6379
03:53:17,960 --> 03:53:19,280
DIAGNOSED WITH BREAST CANCER.

6380
03:53:19,280 --> 03:53:21,680
THE RESEARCH COVERS A RANGE OF 

6381
03:53:21,680 --> 03:53:23,280
FACTORS RELATED TO BREAST CANCER

6382
03:53:23,280 --> 03:53:25,960
AND OTHER CHRONIC DISEASE RISK 

6383
03:53:25,960 --> 03:53:27,280
INCLUDING EARLY LIFE EXPOSURES, 

6384
03:53:27,280 --> 03:53:28,800
SOCIAL ENVIRONMENTAL AND 

6385
03:53:28,800 --> 03:53:30,640
LIFESTYLE FACTORS AND THROUGH 

6386
03:53:30,640 --> 03:53:35,400
COLLABORATIONS AT NIEHS AND 

6387
03:53:35,400 --> 03:53:37,400
ELSEWHERE AND EPIDEMIOLOGIC 

6388
03:53:37,400 --> 03:53:39,360
FACTORS AND CO-INVESTIGATOR OF 

6389
03:53:39,360 --> 03:53:41,040
THE HEALTH STUDY LEADING EFFORTS

6390
03:53:41,040 --> 03:53:44,640
TO STUDY THE IMPACT OF 

6391
03:53:44,640 --> 03:53:48,280
AGRICULTURAL EXPOSURES ON 

6392
03:53:48,280 --> 03:53:50,160
NON-CANCER CHRONIC DISEASE AND A

6393
03:53:50,160 --> 03:53:53,440
COHORT OF PESTICIDE APPLICATORS 

6394
03:53:53,440 --> 03:53:56,880
FOLLOWED SINCE 1987 AND THE GULF

6395
03:53:56,880 --> 03:53:59,360
LONG TERM STUDY A PROSPECTIVE 

6396
03:53:59,360 --> 03:54:01,240
STUDY OF POTENTIAL HEALTH 

6397
03:54:01,240 --> 03:54:02,480
EFFECTS IN INDIVIDUALS INVOLVED 

6398
03:54:02,480 --> 03:54:07,840
IN CLEAN UP OF THE OIL SPILL 

6399
03:54:07,840 --> 03:54:09,120
FOLLOWING THE GULF WATER 

6400
03:54:09,120 --> 03:54:13,320
DISASTER IN THE GULF OF MEXICO.

6401
03:54:13,320 --> 03:54:23,720
WELCOME, DR. SANDLER.

6402
03:54:25,760 --> 03:54:36,000
>>YOU'RE ON MUTE.

6403
03:54:38,320 --> 03:54:41,640
>>THANK YOU FOR THE
INVITATION 

6404
03:54:41,640 --> 03:54:42,400
AND LOVELY INTRODUCTION AND WILL

6405
03:54:42,400 --> 03:54:44,640
TALK ABOUT THE SISTER STUDY 

6406
03:54:44,640 --> 03:54:51,280
TODAY.

6407
03:54:51,280 --> 03:54:53,480
FOR MY PRESENTATION TODAY I'LL 

6408
03:54:53,480 --> 03:54:56,320
GIVE AN OVERVIEW OF THE STUDY 

6409
03:54:56,320 --> 03:54:58,480
AND THE BACKGROUND FOR 

6410
03:54:58,480 --> 03:55:00,120
DEVELOPING THE COHORT, DESCRIBE 

6411
03:55:00,120 --> 03:55:05,440
THE RESOURCE AND POTENTIAL TO 

6412
03:55:05,440 --> 03:55:06,080
ADDRESS ENVIRONMENTAL HEALTH 

6413
03:55:06,080 --> 03:55:11,440
CONCERNS  AND I WASN'T ABLE TO 

6414
03:55:11,440 --> 03:55:12,560
CHOOSE AMONG THE MANY RESEARCH 

6415
03:55:12,560 --> 03:55:15,720
STUDIES WE'VE DONE IN THE COHORT

6416
03:55:15,720 --> 03:55:18,120
SO I MAY HAVE AN OVER ABUNDANCE 

6417
03:55:18,120 --> 03:55:19,920
OF EXAMPLES AND CAN'T GO INTO 

6418
03:55:19,920 --> 03:55:22,240
ANY ONE IN GREAT DEPTH.

6419
03:55:22,240 --> 03:55:23,440
AND END BY CONSIDERING 

6420
03:55:23,440 --> 03:55:26,000
OPPORTUNITIES AND CHALLENGES FOR

6421
03:55:26,000 --> 03:55:27,880
THE FUTURE IN OUR COHORT AND 

6422
03:55:27,880 --> 03:55:29,680
OTHER SIMILAR STUDIES.

6423
03:55:29,680 --> 03:55:33,160
SO THIS GRAPH SHOWS TRENDS IN 

6424
03:55:33,160 --> 03:55:34,960
BREAST CANCER INCIDENTS AND 

6425
03:55:34,960 --> 03:55:39,240
MORTALITY SINCE 1979.

6426
03:55:39,240 --> 03:55:44,200
THE INCIDENTS ROSE QUITE STEEPLY

6427
03:55:44,200 --> 03:55:47,240
UNTIL 2000 AND THE INCIDENTS 

6428
03:55:47,240 --> 03:55:49,640
HAVE REMAINED HIGHER FOR WHITE 

6429
03:55:49,640 --> 03:55:50,640
WOMEN THAN FOR BLACK WOMEN 

6430
03:55:50,640 --> 03:55:52,280
WHEREAS THE MORTALITY RATES ARE 

6431
03:55:52,280 --> 03:55:54,040
HIGHER IN BLACK WOMEN THAN WHITE

6432
03:55:54,040 --> 03:55:54,240
WOMEN.

6433
03:55:54,240 --> 03:55:57,200
YOU CAN ALSO SEE MORTALITY HAS 

6434
03:55:57,200 --> 03:55:59,080
DECREASED OVER TIME IN PART DUE 

6435
03:55:59,080 --> 03:56:01,200
TO THE UPTAKE OF SCREENING BUT 

6436
03:56:01,200 --> 03:56:03,320
LARGELY DUE TO THE ADVANCES IN 

6437
03:56:03,320 --> 03:56:13,160
TREATMENT.

6438
03:56:13,160 --> 03:56:18,200
THIS LED TO WIDESPREAD CONCERNS 

6439
03:56:18,200 --> 03:56:19,480
ABOUT EXPOSURE TO ENVIRONMENTAL 

6440
03:56:19,480 --> 03:56:21,040
CHEMICALS AND THEIR POTENTIAL 

6441
03:56:21,040 --> 03:56:21,640
ASSOCIATIONS WITH INCREASED 

6442
03:56:21,640 --> 03:56:23,080
BREAST CANCER ARE RISK.

6443
03:56:23,080 --> 03:56:24,640
A NUMBER OF ADVOCACY GROUPS 

6444
03:56:24,640 --> 03:56:25,960
CALLED FOR MORE STUDIES.

6445
03:56:25,960 --> 03:56:30,440
THEY LOBBIED CONGRESS AND THE 

6446
03:56:30,440 --> 03:56:30,960
NIEHS AND OTHER FUNDING 

6447
03:56:30,960 --> 03:56:35,280
AGENCIES.

6448
03:56:35,280 --> 03:56:38,040
THERE WAS CONCERN THE EXISTING 

6449
03:56:38,040 --> 03:56:40,120
STUDIES FOCUSSED ON LIFE STYLES,

6450
03:56:40,120 --> 03:56:41,640
HORMONES AND REPRODUCTIVE 

6451
03:56:41,640 --> 03:56:44,600
FACTORS BUT NOT THE LARGER 

6452
03:56:44,600 --> 03:56:54,800
ENVIRONMENT.

6453
03:56:57,920 --> 03:57:02,680
AND WE SEE A TREMENDOUS DECLINE 

6454
03:57:02,680 --> 03:57:04,760
IN BREAST CANCER OR PRECIPITOUS 

6455
03:57:04,760 --> 03:57:05,880
DECLINE IN BREAST CANCER 

6456
03:57:05,880 --> 03:57:09,680
INCIDENTS FOR SOME GROUP.

6457
03:57:09,680 --> 03:57:18,320
BUT BREAST CANCER INCIDENTS 

6458
03:57:18,320 --> 03:57:20,360
REMAIN HIGH AND RAISING AGAIN 

6459
03:57:20,360 --> 03:57:23,880
AND THE LEADING TYPE OF CANCER 

6460
03:57:23,880 --> 03:57:27,280
FOR WOMEN MORE THAN 280,000 NEW 

6461
03:57:27,280 --> 03:57:30,760
CASES PREDICTED FOR 2021 

6462
03:57:30,760 --> 03:57:32,640
REPRESENTING 30% OF ALL CANCERS 

6463
03:57:32,640 --> 03:57:38,280
IN FEMALES.

6464
03:57:38,280 --> 03:57:41,680
IN 2012 AND 2013, SEVERAL 

6465
03:57:41,680 --> 03:57:46,800
REPORTS WERE COMMISSIONED TO 

6466
03:57:46,800 --> 03:57:47,480
DISCUSS THE POTENTIAL RESEARCH 

6467
03:57:47,480 --> 03:57:50,720
THAT NEEDED TO BE DONE TO 

6468
03:57:50,720 --> 03:57:52,760
IDENTIFY ENVIRONMENTAL CAUSES OF

6469
03:57:52,760 --> 03:57:54,640
BREAST CANCER.

6470
03:57:54,640 --> 03:57:58,520
AND THESE REPORTS SUGGESTED THAT

6471
03:57:58,520 --> 03:58:00,280
STUDIES SHOULD BE 

6472
03:58:00,280 --> 03:58:00,920
MULTI-DISCIPLINARY AND SHOULD 

6473
03:58:00,920 --> 03:58:03,280
CONSIDER GENOMICS AND GENE 

6474
03:58:03,280 --> 03:58:04,040
ENVIRONMENT INTERACTIONS AND 

6475
03:58:04,040 --> 03:58:06,640
TAKE A LIFE COURSE APPROACH.

6476
03:58:06,640 --> 03:58:08,800
THE SISTER STUDY HAD JUST 

6477
03:58:08,800 --> 03:58:10,560
COMPLETED ENROLLMENT AT THE TIME

6478
03:58:10,560 --> 03:58:13,640
OF THE REPORTS STARTED WERE 

6479
03:58:13,640 --> 03:58:15,000
COMMISSIONED AND WE'RE WELL 

6480
03:58:15,000 --> 03:58:16,480
POSITIONED TO MEET THESE NEEDS 

6481
03:58:16,480 --> 03:58:17,920
AND CONSIDER NEW APPROACHES SUCH

6482
03:58:17,920 --> 03:58:19,720
AS CHEMICAL MIXTURES AND THE 

6483
03:58:19,720 --> 03:58:22,080
EXPOSOME.

6484
03:58:22,080 --> 03:58:23,200
CURRENT CONCERNS ABOUT THE 

6485
03:58:23,200 --> 03:58:25,760
POTENTIAL HEALTH IMPACTS OF 

6486
03:58:25,760 --> 03:58:26,880
CLIMATE CHANGE BRING NEW URGENCY

6487
03:58:26,880 --> 03:58:31,000
TO STUDIES OF ENVIRONMENT AND 

6488
03:58:31,000 --> 03:58:31,920
ITS RELATIONSHIP TO BREAST 

6489
03:58:31,920 --> 03:58:36,160
CANCER IN OTHER DISEASES.

6490
03:58:36,160 --> 03:58:38,640
SO OUR GOAL WITH THE SISTER 

6491
03:58:38,640 --> 03:58:41,360
STUDY WAS TO ENROLL 50,000 

6492
03:58:41,360 --> 03:58:43,000
VOLUNTEER WOMEN WHO HAD A SISTER

6493
03:58:43,000 --> 03:58:45,880
WITH BREAST CANCER TO PRIMARILY 

6494
03:58:45,880 --> 03:58:47,320
ADDRESS THE CONCERNS WOMEN HAD 

6495
03:58:47,320 --> 03:58:52,360
ABOUT THE RISKS ASSOCIATED WITH 

6496
03:58:52,360 --> 03:58:54,400
ENVIRONMENTAL EXPOSURES AND 

6497
03:58:54,400 --> 03:58:55,080
FOCUSSED ON SISTERS BECAUSE THEY

6498
03:58:55,080 --> 03:58:57,920
IS ABOUT TWICE THE RISK OF 

6499
03:58:57,920 --> 03:58:59,120
DEVELOPING BREAST CANCER 

6500
03:58:59,120 --> 03:59:01,160
THEMSELVES AND ALSO MAY HAVE A 

6501
03:59:01,160 --> 03:59:03,280
HIGHER PREVALENCE OF RELEVANT 

6502
03:59:03,280 --> 03:59:04,600
CHANGE OR EXPOSURES INCLUDING 

6503
03:59:04,600 --> 03:59:05,800
THOSE THAT WEREN'T KNOWN TO US 

6504
03:59:05,800 --> 03:59:07,680
AT THE TIME TO BE ASSOCIATED 

6505
03:59:07,680 --> 03:59:09,280
WITH BREAST CANCER WHICH GIVES 

6506
03:59:09,280 --> 03:59:12,240
US INCREASED POWER TO DETECT 

6507
03:59:12,240 --> 03:59:13,400
ASSOCIATIONS.

6508
03:59:13,400 --> 03:59:14,960
FURTHERMORE, SISTERS WERE 

6509
03:59:14,960 --> 03:59:16,320
POTENTIALLY HIGHLY MOTIVATED AND

6510
03:59:16,320 --> 03:59:17,800
WE EXPECTED THEIR RESPONSE RATES

6511
03:59:17,800 --> 03:59:20,600
IN THE STUDY OF SISTERS WOULD BE

6512
03:59:20,600 --> 03:59:24,440
HIGH.

6513
03:59:24,440 --> 03:59:28,600
OUR DESIGN WAS INTENDED TO 

6514
03:59:28,600 --> 03:59:30,080
ADDRESS LIMITATIONS OF PRIOR 

6515
03:59:30,080 --> 03:59:31,920
STUDIES IN BREEFT CANCER AND 

6516
03:59:31,920 --> 03:59:33,960
GIVES US AN OPPORTUNITY TO STUDY

6517
03:59:33,960 --> 03:59:35,880
A RANGE OF HEALTH OUTCOMES AS 

6518
03:59:35,880 --> 03:59:38,120
WELL AS TO CONTINUE TO FOLLOW 

6519
03:59:38,120 --> 03:59:39,200
THESE WOMEN IN STUDY 

6520
03:59:39,200 --> 03:59:42,640
ENVIRONMENTAL IMPACTS ON 

6521
03:59:42,640 --> 03:59:45,400
SURVIVAL AND HEALTH OUTCOMES 

6522
03:59:45,400 --> 03:59:55,920
AFTER A BREAST CANCER DIAGNOSIS.

6523
04:00:00,480 --> 04:00:04,600
OUR GOAL WAS TO ENROLL 50,000 

6524
04:00:04,600 --> 04:00:09,720
WOMEN BETWEEN 34 AND 74 AND IT 

6525
04:00:09,720 --> 04:00:11,320
CONSISTED OF MANY QUESTIONNAIRES

6526
04:00:11,320 --> 04:00:13,240
THAT AND TELEPHONE INTERVIEWS 

6527
04:00:13,240 --> 04:00:16,440
AND SOME COMPLETED 

6528
04:00:16,440 --> 04:00:18,040
QUESTIONNAIRES AS WELL AS A HOME

6529
04:00:18,040 --> 04:00:20,480
EXAM DURING WHICH WE MADE 

6530
04:00:20,480 --> 04:00:22,240
MEASUREMENTS AND COLLECTED BLOOD

6531
04:00:22,240 --> 04:00:22,480
SAMPLES.

6532
04:00:22,480 --> 04:00:26,000
WOMEN HAD BEEN FOLLOWED EVERY 

6533
04:00:26,000 --> 04:00:27,880
SINCE WITH ANNUAL HEALTH UPDATES

6534
04:00:27,880 --> 04:00:29,800
AND EVERY THREE YEARS A 

6535
04:00:29,800 --> 04:00:32,600
COMPREHENSIVE QUESTIONNAIRE THAT

6536
04:00:32,600 --> 04:00:34,320
COLLECTS INFORMATION ON CHANGES 

6537
04:00:34,320 --> 04:00:36,160
ON HEALTH AND CHANGES ON 

6538
04:00:36,160 --> 04:00:36,520
EXPOSURES.

6539
04:00:36,520 --> 04:00:38,240
OUR RESPONSE RATES HAVE REMAINED

6540
04:00:38,240 --> 04:00:46,600
HIGH AT AROUND 90%.

6541
04:00:46,600 --> 04:00:53,400
IN 2003 WE LOOKED AT WOMEN WHO 

6542
04:00:53,400 --> 04:00:55,440
DEVELOPED BREAST CANCER IN THE 

6543
04:00:55,440 --> 04:00:58,720
INTERVENING YEARS AND SAMPLE OF 

6544
04:00:58,720 --> 04:01:00,720
THE REST OF THE COHORT.

6545
04:01:00,720 --> 04:01:02,600
AND WOMEN DEVELOPED BREAST 

6546
04:01:02,600 --> 04:01:03,880
CANCER AND OTHER HEALTH 

6547
04:01:03,880 --> 04:01:04,400
CONDITIONS.

6548
04:01:04,400 --> 04:01:06,520
FOR THOSE WHO REPORT NEW 

6549
04:01:06,520 --> 04:01:08,040
DIAGNOSIS IN BREAST CANCER OR 

6550
04:01:08,040 --> 04:01:09,400
OVARIAN CANCER WE'VE BEEN 

6551
04:01:09,400 --> 04:01:11,360
COLLECTING MEDICAL RECORDS IN 

6552
04:01:11,360 --> 04:01:13,080
TUMOR TISSUE SAMPLES FOR OTHER 

6553
04:01:13,080 --> 04:01:15,080
CANCERS WE COLLECT PATHOLOGY 

6554
04:01:15,080 --> 04:01:16,680
REPORTS AND FOR OTHER CONDITIONS

6555
04:01:16,680 --> 04:01:18,920
WE CARRY OUT MEDICAL RECORD 

6556
04:01:18,920 --> 04:01:23,000
VALIDATION AS NEEDED.

6557
04:01:23,000 --> 04:01:25,680
TODAY THROUGH OCTOBER 2020 OUR 

6558
04:01:25,680 --> 04:01:28,240
MOST RECENT DATA RELEASE MORE 

6559
04:01:28,240 --> 04:01:30,880
THAN 4,000 WOMEN HAVE REPORTED A

6560
04:01:30,880 --> 04:01:32,000
NEW DIAGNOSIS IN BREAST CANCER.

6561
04:01:32,000 --> 04:01:34,080
A LARGE NUMBER OF CASES WHICH 

6562
04:01:34,080 --> 04:01:35,720
AGAIN IS TWICE WHAT WE WOULD 

6563
04:01:35,720 --> 04:01:39,080
HAVE EXPECTED IN A RANDOM 

6564
04:01:39,080 --> 04:01:40,600
POPULATION SAMPLE.

6565
04:01:40,600 --> 04:01:43,720
ALLOWS US TO STUDY SUB TYPES OF 

6566
04:01:43,720 --> 04:01:44,520
BREAST CANCER AND POPULATION 

6567
04:01:44,520 --> 04:01:47,960
SAMPLES.

6568
04:01:47,960 --> 04:01:53,000
OUR GOAL HAS BEEN TO ENROLL IN 

6569
04:01:53,000 --> 04:01:55,560
DIVERSE COHORT BY GEOGRAPHY, 

6570
04:01:55,560 --> 04:01:57,840
RATE, ETHNICITY AND EXPOSURES.

6571
04:01:57,840 --> 04:02:01,080
WE ENROLL PARTICIPANTS FROM 

6572
04:02:01,080 --> 04:02:02,480
ACROSS THE UNITED STATES AND 

6573
04:02:02,480 --> 04:02:03,640
PUERTO RICO.

6574
04:02:03,640 --> 04:02:08,960
WE WERE SUCCESSFUL IN THAT 

6575
04:02:08,960 --> 04:02:13,200
REGARD.

6576
04:02:13,200 --> 04:02:18,360
THE COHORTS WERE LESS DIVERSE 

6577
04:02:18,360 --> 04:02:24,800
AND 83% SELF-ALL RIREPORTED 

6578
04:02:24,800 --> 04:02:26,400
NON-HISPANIC AND WE HAVE 

6579
04:02:26,400 --> 04:02:27,880
HISPANIC WOMEN AND BLACK WOMEN 

6580
04:02:27,880 --> 04:02:28,400
IN THE COHORT.

6581
04:02:28,400 --> 04:02:30,800
MORE THAN HALF THE COHORT 

6582
04:02:30,800 --> 04:02:36,600
COMPLETED A COLLEGE DEGREE AND 

6583
04:02:36,600 --> 04:02:40,560
THE AVERAGE INCOME PER PERSON 

6584
04:02:40,560 --> 04:02:48,480
AND WE HAVE HOUSEHOLDS TWICE 

6585
04:02:48,480 --> 04:02:54,960
THAT AND WE CAN BETTER 

6586
04:02:54,960 --> 04:02:56,920
UNDERSTAND WHO WE DIDN'T INCLUDE

6587
04:02:56,920 --> 04:03:00,280
THROUGH MORTALITY LINKAGE AND 

6588
04:03:00,280 --> 04:03:01,680
CANCER REGISTRY LINKAGE 3,000 

6589
04:03:01,680 --> 04:03:02,920
WOMEN WHO DIDN'T FULLY COMPLETE 

6590
04:03:02,920 --> 04:03:03,720
THE ENROLLMENT.

6591
04:03:03,720 --> 04:03:06,920
THIS IS JUST TO GIVE YOU AN IDEA

6592
04:03:06,920 --> 04:03:08,640
OF THE NUMBERS OF OTHER 

6593
04:03:08,640 --> 04:03:09,960
DIAGNOSES THAT HAVE BEEN 

6594
04:03:09,960 --> 04:03:11,480
REPORTED TO US DURING THE SISTER

6595
04:03:11,480 --> 04:03:15,840
STUDY WHICH ALLOW US TO STUDY 

6596
04:03:15,840 --> 04:03:16,440
THE FULL COMPLEMENT OF HEALTH 

6597
04:03:16,440 --> 04:03:24,160
INFLUENCE.

6598
04:03:24,160 --> 04:03:26,960
AROUND WE LOOKED AT 

6599
04:03:26,960 --> 04:03:27,920
SUSCEPTIBILITY FROM FETAL 

6600
04:03:27,920 --> 04:03:30,160
EXPOSURES TO EXPOSURES DURING 

6601
04:03:30,160 --> 04:03:31,720
ESPECIALLY DURING THE TIME OF 

6602
04:03:31,720 --> 04:03:34,600
PUBERTY AND REPRODUCTIVE YEARS 

6603
04:03:34,600 --> 04:03:37,840
AND AROUND PERI MENOPAUSE.

6604
04:03:37,840 --> 04:03:39,720
OUR QUESTIONNAIRES COVER A RANGE

6605
04:03:39,720 --> 04:03:43,920
OF EXPOSURES AND AT FOLLOW-UP WE

6606
04:03:43,920 --> 04:03:48,280
UPDATE MANY OF THE EXPOSURE 

6607
04:03:48,280 --> 04:03:49,200
QUESTIONS AS WELL AS UPDATE 

6608
04:03:49,200 --> 04:03:49,960
HEALTH STATUS.

6609
04:03:49,960 --> 04:03:52,600
SO THE SOURCES OF ENVIRONMENTAL 

6610
04:03:52,600 --> 04:03:54,080
DATA IN THE COHORT ARE VARIED.

6611
04:03:54,080 --> 04:03:55,880
IN ADDITION TO THE 

6612
04:03:55,880 --> 04:03:57,480
QUESTIONNAIRES WHICH ALLOW US TO

6613
04:03:57,480 --> 04:03:59,760
LOOK AT CURRENT AND PAST 

6614
04:03:59,760 --> 04:04:01,080
EXPOSURES, WE CAN MEASURE 

6615
04:04:01,080 --> 04:04:04,400
EXPOSURES IN BIOLOGIC SAMPLES OR

6616
04:04:04,400 --> 04:04:05,880
HOUSEHOLD DUST FROM SAMPLES WE 

6617
04:04:05,880 --> 04:04:07,200
COLLECTED IN THE COHORT AND HAVE

6618
04:04:07,200 --> 04:04:09,040
BEEN MAKING INCREASING USE OF 

6619
04:04:09,040 --> 04:04:12,680
WIDELY AVAILABLE OR INCREASING 

6620
04:04:12,680 --> 04:04:14,960
NUMBERS OF DATABASES FOR 

6621
04:04:14,960 --> 04:04:17,000
ENVIRONMENTAL EXPOSURES THAT CAN

6622
04:04:17,000 --> 04:04:20,120
BE GEOGRAPHICALLY LINKED TO THE 

6623
04:04:20,120 --> 04:04:21,280
RESIDENCES OF STUDY 

6624
04:04:21,280 --> 04:04:25,280
PARTICIPANTS.

6625
04:04:25,280 --> 04:04:28,560
WE'VE CONSIDERED MAKING DIRECT 

6626
04:04:28,560 --> 04:04:32,040
EXPOSURE MONITORING OR INVITING 

6627
04:04:32,040 --> 04:04:33,800
PARTICIPANTS TO WEAR PERSONAL 

6628
04:04:33,800 --> 04:04:35,520
MONITORING DEVICES BUT THIS IS 

6629
04:04:35,520 --> 04:04:37,840
CHALLENGING IN THE STUDY AS 

6630
04:04:37,840 --> 04:04:39,200
LARGE AS OURS.

6631
04:04:39,200 --> 04:04:40,400
MEASUREMENTS DON'T REALLY SCALE 

6632
04:04:40,400 --> 04:04:41,400
UP AND ONLY CAPTURE CURRENT 

6633
04:04:41,400 --> 04:04:51,600
EXPOSURES.

6634
04:04:54,760 --> 04:05:00,520
AND WE LOOKED AT EXPOSOME 

6635
04:05:00,520 --> 04:05:04,560
STUDIES FOR SAMPLES IN THE 

6636
04:05:04,560 --> 04:05:07,840
COHORT AND ALSO EPIGENETIC 

6637
04:05:07,840 --> 04:05:08,640
MECHANISMS ARE AFFECT EARLY 

6638
04:05:08,640 --> 04:05:11,600
DEVELOPMENT AND AGING AND ALSO 

6639
04:05:11,600 --> 04:05:12,520
AFFECTED BY ENVIRONMENTAL LIFE 

6640
04:05:12,520 --> 04:05:14,880
TIME EXPOSURES AS WE 

6641
04:05:14,880 --> 04:05:17,400
DEMONSTRATED IN OUR COHORT.

6642
04:05:17,400 --> 04:05:23,320
MANY CPGs AND METHLATION-BASED 

6643
04:05:23,320 --> 04:05:26,520
MARKERS OF ENVIRONMENTAL EXCUSE 

6644
04:05:26,520 --> 04:05:28,760
ME, OF AGE ACCELERATION HAS BEEN

6645
04:05:28,760 --> 04:05:29,400
LINKED TO EXPOSURES IN THE 

6646
04:05:29,400 --> 04:05:32,520
COHORT AND THE GOAL IS TO 

6647
04:05:32,520 --> 04:05:34,400
IDENTIFY METHYLATION BASED 

6648
04:05:34,400 --> 04:05:35,600
SIGNATURES AND EXPOSURE AS HAS 

6649
04:05:35,600 --> 04:05:39,800
BEEN DONE FOR SMOKING.

6650
04:05:39,800 --> 04:05:41,160
OUR RESEARCH HAS BEEN WIDE 

6651
04:05:41,160 --> 04:05:44,600
RANGING WE FOCUS ON A NUMBER OF 

6652
04:05:44,600 --> 04:05:47,640
DISEASES BESIDES BREAST CANCER 

6653
04:05:47,640 --> 04:05:54,600
AND WE DO THIS WORK INTERIM -- 

6654
04:05:54,600 --> 04:05:56,040
INTRAMURALLY AND IN OUR BRANCH 

6655
04:05:56,040 --> 04:05:59,800
AND LOOKING SPECIFICALLY FOR 

6656
04:05:59,800 --> 04:06:04,320
CANCER AS WELL AS CONE  -- 

6657
04:06:04,320 --> 04:06:05,320
CONSORTIA OF RISK DISEASES.

6658
04:06:05,320 --> 04:06:07,080
WE CARRIED OUT A NUMBER OF 

6659
04:06:07,080 --> 04:06:10,320
COLLABORATIVE STUDIES ACROSS THE

6660
04:06:10,320 --> 04:06:11,560
NIH WITHIN EXTRAMURAL COLLEAGUES

6661
04:06:11,560 --> 04:06:13,560
AND STUDENTS AND TO DATE MORE 

6662
04:06:13,560 --> 04:06:15,400
THAN 270 PAPERS HAVE BEEN 

6663
04:06:15,400 --> 04:06:16,760
WRITTEN USING THE SISTER STUDY 

6664
04:06:16,760 --> 04:06:19,160
AND WE'VE BEEN THE BASIS FOR 17 

6665
04:06:19,160 --> 04:06:21,960
EXTRAMURAL GRANTS.

6666
04:06:21,960 --> 04:06:23,720
SO NOW I WANT TO TURN TO SOME 

6667
04:06:23,720 --> 04:06:25,760
EXAMPLES FOR THIS STUDY.

6668
04:06:25,760 --> 04:06:28,840
I'M GOING START WITH EXPOSURES 

6669
04:06:28,840 --> 04:06:32,600
DURING CHILDHOOD.

6670
04:06:32,600 --> 04:06:34,600
THERE'S A LOT OF INTEREST IN THE

6671
04:06:34,600 --> 04:06:36,600
POSSIBILITY THAT AIR POLLUTION 

6672
04:06:36,600 --> 04:06:37,560
IS ASSOCIATED WITH BREAST CANCER

6673
04:06:37,560 --> 04:06:41,120
RISK AND WE WONDERED IF EARLY 

6674
04:06:41,120 --> 04:06:42,520
LIFE EXPOSURE TO AIR POLLUTION 

6675
04:06:42,520 --> 04:06:44,360
WAS A PROBLEM.

6676
04:06:44,360 --> 04:06:46,720
AND AIR POLLUTION DATA BEFORE 

6677
04:06:46,720 --> 04:06:51,320
1990 ARE QUITE LIMITED AND MOST 

6678
04:06:51,320 --> 04:06:53,520
OF OUR PARTICIPANTS WERE BORN 

6679
04:06:53,520 --> 04:06:54,040
BEFORE 1970.

6680
04:06:54,040 --> 04:06:58,840
SO WE HAD TO LOOK AT THIS USING 

6681
04:06:58,840 --> 04:07:00,600
SELF-REPORTED DATA ON ROADS AND 

6682
04:07:00,600 --> 04:07:03,840
TRAFFIC AT THE LONGEST CHILDHOOD

6683
04:07:03,840 --> 04:07:07,640
RESIDENCE AND WERE ABLE TO 

6684
04:07:07,640 --> 04:07:09,160
DEMONSTRATE BREAST CANCER RISK 

6685
04:07:09,160 --> 04:07:11,080
WAS ASSOCIATED WITH NEAR A 

6686
04:07:11,080 --> 04:07:13,040
ROADWAY OF HEAVY TRAFFIC WHICH 

6687
04:07:13,040 --> 04:07:22,560
IS A MARKER OF AIR POLLUTION.

6688
04:07:22,560 --> 04:07:24,680
WE ALSO LOOKED AT PHYSICAL 

6689
04:07:24,680 --> 04:07:26,760
ACTIVITY IN CHILDHOOD AND THOSE 

6690
04:07:26,760 --> 04:07:30,400
THAT ADHERE TO THE HHS GUIDELINE

6691
04:07:30,400 --> 04:07:33,320
FOR ACTIVITY OF SEVEN OR MORE 

6692
04:07:33,320 --> 04:07:37,280
HOURS A WEEK OF EXERCISE HAVE A 

6693
04:07:37,280 --> 04:07:39,520
REDUCED CASE OF BREAST CANCER.

6694
04:07:39,520 --> 04:07:45,360
CIGARETTE SMOKING HAS BEEN AN 

6695
04:07:45,360 --> 04:07:47,720
ELUSIVE EXPOSURE IN RELATION TO 

6696
04:07:47,720 --> 04:07:49,520
BREAST CANCER RISK AND 

6697
04:07:49,520 --> 04:07:55,960
INCONSISTENT IN TERMS OF ACTIVE 

6698
04:07:55,960 --> 04:07:58,200
RISK SMOKING AND TO PASSIVE 

6699
04:07:58,200 --> 04:07:59,760
SMOKING WE DID NOT DEMONSTRATE 

6700
04:07:59,760 --> 04:08:02,040
AN INCREASED RISK FOR ADULT 

6701
04:08:02,040 --> 04:08:04,040
PASSIVE RISK EXPOSURE BUT DID 

6702
04:08:04,040 --> 04:08:06,520
SEE A SMALL SUGGESTIVE INCREASE 

6703
04:08:06,520 --> 04:08:08,480
IN RISK FOR BREAST CANCER 

6704
04:08:08,480 --> 04:08:11,200
ASSOCIATED WITH INCREASING 

6705
04:08:11,200 --> 04:08:12,600
LEVELS OF EXPOSURE TO 

6706
04:08:12,600 --> 04:08:15,480
ENVIRONMENTAL TOBACCO SMOKE IN 

6707
04:08:15,480 --> 04:08:20,800
CHILDHOOD AND IN UTERO.

6708
04:08:20,800 --> 04:08:22,600
SOMETHING THAT'S BEEN A LONG 

6709
04:08:22,600 --> 04:08:27,280
STANDING INTEREST OF OURS AND 

6710
04:08:27,280 --> 04:08:28,560
MOTIVATED BY THE HEALTH EFFECTS 

6711
04:08:28,560 --> 04:08:29,360
ASSOCIATED WITH THE USE OF 

6712
04:08:29,360 --> 04:08:30,360
PERSONAL CARE PRODUCTS.

6713
04:08:30,360 --> 04:08:34,920
MANY OF THESE PRODUCTS CONTAIN 

6714
04:08:34,920 --> 04:08:36,280
ENDOCRINE DISRUPTING AND TOXIC 

6715
04:08:36,280 --> 04:08:36,560
CHEMICALS.

6716
04:08:36,560 --> 04:08:38,080
WE ADMINISTERED A QUESTIONNAIRE 

6717
04:08:38,080 --> 04:08:40,640
AND ENROLLMENT THAT FOCUSSED ON 

6718
04:08:40,640 --> 04:08:43,800
PERSONAL CARE PRODUCT USE AT THE

6719
04:08:43,800 --> 04:08:45,400
AGES BETWEEN 10 AND 13 AROUND 

6720
04:08:45,400 --> 04:08:48,600
THE TIMING OF PUBERTY AND 12 

6721
04:08:48,600 --> 04:08:53,960
MONTHS BEFORE ENROLLMENT.

6722
04:08:53,960 --> 04:08:59,320
WE CONSIDERED FREQUENT USE OF 

6723
04:08:59,320 --> 04:09:06,040
HAIR STRAIGHTENERS AND IN TERMS 

6724
04:09:06,040 --> 04:09:09,320
OF ADOLESCENCE TWO FOLD HIGHER 

6725
04:09:09,320 --> 04:09:12,240
RISK OF BREAST CANCER RISK AMONG

6726
04:09:12,240 --> 04:09:15,320
THOSE WHO FREQUENTLY USED HAIR 

6727
04:09:15,320 --> 04:09:15,920
STRAIGHTENERS.

6728
04:09:15,920 --> 04:09:18,760
AND WE ALSO FOUND AN ASSOCIATION

6729
04:09:18,760 --> 04:09:20,200
WITH FREQUENT USE OF THESE 

6730
04:09:20,200 --> 04:09:22,120
CHEMICAL HAIR STRAIGHTENERS IN 

6731
04:09:22,120 --> 04:09:24,960
THE YEAR BEFORE ENROLLMENT.

6732
04:09:24,960 --> 04:09:28,080
50% INCREASE IN THE RISK SHOWN 

6733
04:09:28,080 --> 04:09:28,320
HERE.

6734
04:09:28,320 --> 04:09:32,200
OF NOTE, THE USE OF CHEMICAL 

6735
04:09:32,200 --> 04:09:36,200
STRAIGHTENERS IS FAR MORE COMMON

6736
04:09:36,200 --> 04:09:37,440
AMONG BLACK WOMEN AND U.S. AS A 

6737
04:09:37,440 --> 04:09:40,120
WHOLE BUT THE ASSOCIATIONS WERE 

6738
04:09:40,120 --> 04:09:43,880
SIMILAR REGARDING RACE.

6739
04:09:43,880 --> 04:09:46,200
WE ALSO FOUND THOUGH I'M NOT 

6740
04:09:46,200 --> 04:09:47,680
SHOWING IT BREAST CANCER RISK 

6741
04:09:47,680 --> 04:09:50,720
WAS HIGHER IN ASSOCIATION WITH 

6742
04:09:50,720 --> 04:09:54,320
USE OF PERMANENT HAIR DYES AND 

6743
04:09:54,320 --> 04:09:55,240
THE RISK WAS SLIGHTLY STRONGER 

6744
04:09:55,240 --> 04:09:57,840
IN THIS CASE.

6745
04:09:57,840 --> 04:10:01,520
I ALSO WANTED TO POINT OUT THAT 

6746
04:10:01,520 --> 04:10:04,160
STRAIGHTENERS HAVE ALSO BEEN 

6747
04:10:04,160 --> 04:10:06,520
ASSOCIATED WITH OTHER HORMONE 

6748
04:10:06,520 --> 04:10:09,320
MEDIATED CANCERS IN OUR COHORT 

6749
04:10:09,320 --> 04:10:15,360
AND WITH OUT -- UTERINE CANCER 

6750
04:10:15,360 --> 04:10:18,240
IN A REPORT THAT JUST CAME OUT 

6751
04:10:18,240 --> 04:10:18,880
THIS WEEK.

6752
04:10:18,880 --> 04:10:20,160
THERE'S BEEN A LOT OF INTEREST 

6753
04:10:20,160 --> 04:10:21,840
IN AIR POLLUTION AND BREAST 

6754
04:10:21,840 --> 04:10:25,520
CANCER AND IN TERMS OF EXPOSURE 

6755
04:10:25,520 --> 04:10:28,040
DURING ADULTHOOD CO2 HAS BEEN 

6756
04:10:28,040 --> 04:10:33,080
ASSOCIATED WOMAN -- WITH A SMALL

6757
04:10:33,080 --> 04:10:36,200
INCREASE AND USING AIR POLLUTION

6758
04:10:36,200 --> 04:10:38,520
MONITORING DATA AND LAND USE 

6759
04:10:38,520 --> 04:10:40,200
REGRESSION MODELS WE IN THE 

6760
04:10:40,200 --> 04:10:41,240
SISTER STUDY WE FOUND 

6761
04:10:41,240 --> 04:10:43,760
ASSOCIATIONS BETWEEN AIR 

6762
04:10:43,760 --> 04:10:44,800
POLLUTION AND BREAST CANCER.

6763
04:10:44,800 --> 04:10:50,200
IN 2015 WE REPORTED NO2 WAS 

6764
04:10:50,200 --> 04:10:52,240
ASSOCIATED WITH A 10% INCREASE 

6765
04:10:52,240 --> 04:10:55,440
IN BREAST CANCER RISK ESPECIALLY

6766
04:10:55,440 --> 04:10:57,440
ER POSITIVE BREAST CANCER BUT 

6767
04:10:57,440 --> 04:11:01,280
FOUND NO ASSOCIATION WITH PM2.5.

6768
04:11:01,280 --> 04:11:05,080
A FEW YEARS LATER IN 2019 WITH A

6769
04:11:05,080 --> 04:11:08,320
LONGER FOLLOW-UP WE AGAIN FOUND 

6770
04:11:08,320 --> 04:11:10,640
IN A SMALL INCREASE IN RISK 

6771
04:11:10,640 --> 04:11:13,880
ASSOCIATED WITH NO2 AND HERE WE 

6772
04:11:13,880 --> 04:11:16,120
STARTED TO SEE THE SUGGESTION OF

6773
04:11:16,120 --> 04:11:22,640
A RISK ASSOCIATED WITH PN2.5.

6774
04:11:22,640 --> 04:11:25,880
ONE REASON THAT STUDIES OF PM2.5

6775
04:11:25,880 --> 04:11:28,600
MAY HAVE NOT CONSISTENTLY 

6776
04:11:28,600 --> 04:11:31,480
DEMONSTRATED RISK IS THAT 

6777
04:11:31,480 --> 04:11:34,080
PARTICULATE MATTER VARIES ACROSS

6778
04:11:34,080 --> 04:11:34,680
THE UNITED STATES.

6779
04:11:34,680 --> 04:11:39,320
IT'S NOT ONE SINGLE THING AND 

6780
04:11:39,320 --> 04:11:42,680
GEOGRAPHIC HETEROGENEITY IN THE 

6781
04:11:42,680 --> 04:11:47,440
CHEMICAL COMPOSITION MAY MAKE A 

6782
04:11:47,440 --> 04:11:49,520
SENSE AND THE AIR POLLUTION 

6783
04:11:49,520 --> 04:11:51,240
SOURCES VARY GEOGRAPHICALLY AND 

6784
04:11:51,240 --> 04:11:53,880
WE DID DEMONSTRATE IN A STUDY 

6785
04:11:53,880 --> 04:11:57,320
THAT WAS LED BY MY COLLEAGUE 

6786
04:11:57,320 --> 04:12:00,240
ALEXANDER WHITE THAT THE PM2.5 

6787
04:12:00,240 --> 04:12:02,320
IS ASSOCIATED WITH BREAST CANCER

6788
04:12:02,320 --> 04:12:04,600
RISK IN THE WESTERN U.S. BUT NOT

6789
04:12:04,600 --> 04:12:12,280
ELSEWHERE.

6790
04:12:12,280 --> 04:12:17,520
MANY OF THE LARGE COHORT STUDIES

6791
04:12:17,520 --> 04:12:19,960
FOCUSSED ON BREAST CANCER AND 

6792
04:12:19,960 --> 04:12:22,280
OTHER DISEASES IN WOMEN HAVE 

6793
04:12:22,280 --> 04:12:23,760
BEEN FOCUSSED ON DIET.

6794
04:12:23,760 --> 04:12:27,400
MOST OF THESE STUDIES HAVE 

6795
04:12:27,400 --> 04:12:30,120
LOOKED AT INDIVIDUAL DIET 

6796
04:12:30,120 --> 04:12:31,840
CONSTITUENTS AND NUTRIENTS BUT 

6797
04:12:31,840 --> 04:12:35,840
PEOPLE DON'T EAT A SINGLE FOOD 

6798
04:12:35,840 --> 04:12:38,040
AT A TIME, EXCUSE ME, THEY DON'T

6799
04:12:38,040 --> 04:12:40,240
EAT A SINGLE FOOD OR NUTRIENT SO

6800
04:12:40,240 --> 04:12:43,080
FOCUSSING ON PATTERNS MAY BE 

6801
04:12:43,080 --> 04:12:45,080
MORE INFORMATIVE.

6802
04:12:45,080 --> 04:12:48,520
WE CONSIDERED A NUMBER OF 

6803
04:12:48,520 --> 04:12:51,320
HEALTHY EATING INDICES USED ON 

6804
04:12:51,320 --> 04:12:54,400
U.S. GUIDELINES FOR EATING AND 

6805
04:12:54,400 --> 04:12:57,320
SHOWING THE U.S. FOOD PYRAMID, 

6806
04:12:57,320 --> 04:12:59,200
AN EXAMPLE OF THE FOOD PYRAMID 

6807
04:12:59,200 --> 04:13:00,600
AND HAVE SHOWN SEVERAL OF THESE 

6808
04:13:00,600 --> 04:13:02,160
DIETS OR ALL THE ONES WE LOOKED 

6809
04:13:02,160 --> 04:13:04,280
AT WERE ASSOCIATED WITH REDUCED 

6810
04:13:04,280 --> 04:13:07,360
RISK OF BREAST CANCER FOR WOMEN 

6811
04:13:07,360 --> 04:13:12,240
WHO EAT A HEALTHY DIET.

6812
04:13:12,240 --> 04:13:14,200
WE'VE BECOME INTERESTED IN MORE 

6813
04:13:14,200 --> 04:13:16,360
MECHANISTIC DIETS HOWEVER, AND 

6814
04:13:16,360 --> 04:13:21,320
THESE ARE BASED ON A PRESUMED

6815
04:13:21,320 --> 04:13:25,760
YO -- BIOLOGIC COMBINATIONS OF 

6816
04:13:25,760 --> 04:13:29,400
FOODS AND CONSUMING A 

6817
04:13:29,400 --> 04:13:32,600
PRO-INFLAMMATORY DIET WAS 

6818
04:13:32,600 --> 04:13:33,920
ASSOCIATED WITH INCREASED RISK 

6819
04:13:33,920 --> 04:13:38,640
OF ESTROGEN NEGATIVE AND TRIPLE 

6820
04:13:38,640 --> 04:13:41,720
NEGATIVE BREAST CANCER.

6821
04:13:41,720 --> 04:13:49,400
AND SIMILARLY AN ANTI-OXIDANT 

6822
04:13:49,400 --> 04:13:55,520
DIET WAS ASSOCIATED WITH A 

6823
04:13:55,520 --> 04:13:57,960
NEGATIVE RESULT AND INVERSE 

6824
04:13:57,960 --> 04:13:59,960
REACTIONS AND WE LOOKED AT 

6825
04:13:59,960 --> 04:14:01,960
EXPOSURE TO AMBIENT LIGHT AT 

6826
04:14:01,960 --> 04:14:03,160
NIGHT IN RELATION TO OBESITY.

6827
04:14:03,160 --> 04:14:07,320
I'LL TURN NOW TO LOOKING AT THE 

6828
04:14:07,320 --> 04:14:08,120
FACTORS OTHER THAN BREAST 

6829
04:14:08,120 --> 04:14:09,000
CANCER.

6830
04:14:09,000 --> 04:14:10,240
SELF-REPORTED EXPOSURE TO ANY 

6831
04:14:10,240 --> 04:14:12,200
INDOOR LIGHT BUT ESPECIALLY 

6832
04:14:12,200 --> 04:14:14,720
SLEEPING WITH THE LIGHT OR TV ON

6833
04:14:14,720 --> 04:14:20,600
WAS ASSOCIATED WITH INCREASED 

6834
04:14:20,600 --> 04:14:23,080
OBESITY AT ENROLLMENT AS WELL AS

6835
04:14:23,080 --> 04:14:25,960
DURING FOLLOW-UP AS SHOWN.

6836
04:14:25,960 --> 04:14:28,880
IT WAS ASSOCIATED WITH INCIDENT 

6837
04:14:28,880 --> 04:14:30,240
WEIGHT GAIN AND MEASURES OF 

6838
04:14:30,240 --> 04:14:32,600
OBESITY AT THE TIME OF 

6839
04:14:32,600 --> 04:14:35,560
FOLLOW-UP.

6840
04:14:35,560 --> 04:14:37,800
SLEEPING WITH THE LIGHT OR TV ON

6841
04:14:37,800 --> 04:14:40,640
IN THE ROOM IS ALSO ASSOCIATED 

6842
04:14:40,640 --> 04:14:45,160
WITH PREVALENCE OF HYPERTENSION 

6843
04:14:45,160 --> 04:14:47,640
OUTDOOR LIGHT AT NIGHT COLLECTED

6844
04:14:47,640 --> 04:14:51,040
MEASURES USING SATELLITE DATA 

6845
04:14:51,040 --> 04:14:52,840
WAS ASSOCIATED WITH INCIDENT 

6846
04:14:52,840 --> 04:14:54,480
HYPERTENSION ONLY AMONG THOSE 

6847
04:14:54,480 --> 04:14:55,920
THAT REPORTED OUTDOOR LIGHT WAS 

6848
04:14:55,920 --> 04:14:56,920
GETTING IN THE ROOM WHILE 

6849
04:14:56,920 --> 04:15:00,680
SLEEPING.

6850
04:15:00,680 --> 04:15:03,120
FINALLY, TO BRING US BACK TO 

6851
04:15:03,120 --> 04:15:03,920
BREAST CANCER WE SAW SLEEPING 

6852
04:15:03,920 --> 04:15:07,760
WITH A LIGHT OR TV ON WAS 

6853
04:15:07,760 --> 04:15:08,600
ASSOCIATED WITH AN INCREASED 

6854
04:15:08,600 --> 04:15:14,560
RISK OF BREAST CANCER.

6855
04:15:14,560 --> 04:15:16,640
WE CONSIDERED A NUMBER OF 

6856
04:15:16,640 --> 04:15:18,040
EXPOSURES IN RELATION TO 

6857
04:15:18,040 --> 04:15:19,240
HYPERTENSION AND ONE THING ABOUT

6858
04:15:19,240 --> 04:15:21,880
HYPERTENSION IS WE HAVE A GOOD 

6859
04:15:21,880 --> 04:15:25,520
MEASURE AND WE MEASURED THIS AT 

6860
04:15:25,520 --> 04:15:27,280
ENROLLMENT AS PART OF THE HOME 

6861
04:15:27,280 --> 04:15:27,640
EXAM.

6862
04:15:27,640 --> 04:15:32,880
WE SHOWED A NUMBER OF AIRBORNE 

6863
04:15:32,880 --> 04:15:36,320
POLLUTANTS RELATED TO FOSSIL 

6864
04:15:36,320 --> 04:15:37,960
FUEL AND COMBUSTION PRODUCTS 

6865
04:15:37,960 --> 04:15:40,600
WERE ASSOCIATED WITH AN 

6866
04:15:40,600 --> 04:15:41,960
INCREASED RISK OF HYPERTENSION.

6867
04:15:41,960 --> 04:15:43,440
WE USED DATA FROM SOMETHING 

6868
04:15:43,440 --> 04:15:47,280
CALLED THE NATIONAL AIR TOXIC 

6869
04:15:47,280 --> 04:15:48,600
ASSESSMENT THAT IS MODELLED 

6870
04:15:48,600 --> 04:15:54,400
POLLUTION DATA FROM THE EPA AS 

6871
04:15:54,400 --> 04:15:55,640
WELL AS USING MONITOR DATA AND 

6872
04:15:55,640 --> 04:15:57,680
THE MIXTURE OF THESE NINE 

6873
04:15:57,680 --> 04:15:59,400
CHEMICALS THAT WE LOOKED AT WAS 

6874
04:15:59,400 --> 04:16:01,680
ASSOCIATED WITH A SMALL INCREASE

6875
04:16:01,680 --> 04:16:05,120
IN HYPERTENSION RISK AND RISK 

6876
04:16:05,120 --> 04:16:05,600
THAT WAS GREATER AMONG 

6877
04:16:05,600 --> 04:16:08,920
PARTICIPANTS.

6878
04:16:08,920 --> 04:16:12,080
WE DIDN'T WANT TO FORGET THE 

6879
04:16:12,080 --> 04:16:13,240
SOCIAL ENVIRONMENT WE THINK IS 

6880
04:16:13,240 --> 04:16:18,360
MORE IMPORTANT IN CANCER RISK.

6881
04:16:18,360 --> 04:16:21,080
WE EVALUATED NEIGHBORHOOD SOCIO 

6882
04:16:21,080 --> 04:16:24,200
ECONOMIC FACTORS USING THE AREA 

6883
04:16:24,200 --> 04:16:25,280
DEPRIVATION INDEX AND EVEN IN 

6884
04:16:25,280 --> 04:16:27,320
OUR COHORT WHERE MOST OF THE 

6885
04:16:27,320 --> 04:16:28,800
PEOPLE DO NOT LIVE IN 

6886
04:16:28,800 --> 04:16:30,640
NEIGHBORHOODS THAT HAVE A HIGH 

6887
04:16:30,640 --> 04:16:33,680
LEVEL OF NEIGHBORHOOD 

6888
04:16:33,680 --> 04:16:36,600
DEPRIVATION, THE INCREASING 

6889
04:16:36,600 --> 04:16:38,920
LEVELS ASSOCIATED WITH INCREASED

6890
04:16:38,920 --> 04:16:40,920
HYPERTENSION RISK.

6891
04:16:40,920 --> 04:16:47,960
THIS MEASURE WAS ALSO ASSOCIATED

6892
04:16:47,960 --> 04:16:51,360
WITH VARIOUS ACCELERATED 

6893
04:16:51,360 --> 04:16:52,600
BIOLOGIC AGE.

6894
04:16:52,600 --> 04:16:55,000
I WANT TO POINT OUT MANY OF 

6895
04:16:55,000 --> 04:16:57,120
THESE HAVE BEEN ASSOCIATED WITH 

6896
04:16:57,120 --> 04:16:58,080
INCREASED BREAST CANCER RISK IN 

6897
04:16:58,080 --> 04:17:01,520
OUR STUDY AND NOT TO END ON A 

6898
04:17:01,520 --> 04:17:02,440
TOTALLY NEGATIVE NOTE WE'RE ONLY

6899
04:17:02,440 --> 04:17:04,320
LOOKING AT THINGS THAT ARE BAD 

6900
04:17:04,320 --> 04:17:05,200
FOR YOU WE HAVE BEEN 

6901
04:17:05,200 --> 04:17:06,280
COLLABORATING WITH COLLEAGUES 

6902
04:17:06,280 --> 04:17:10,120
FROM THE EPA TO CONSIDER THE 

6903
04:17:10,120 --> 04:17:11,280
IMPACT OF GREEN SPACE WHICH 

6904
04:17:11,280 --> 04:17:13,320
MIGHT BE BENEFICIAL IN TERMS OF 

6905
04:17:13,320 --> 04:17:14,520
HEALTH RISKS AND HERE I'M 

6906
04:17:14,520 --> 04:17:16,320
SHOWING AN EXAMPLE OF ONE OF 

6907
04:17:16,320 --> 04:17:19,120
THESE STUDIES WHERE WE SHOWED 

6908
04:17:19,120 --> 04:17:20,600
OVER ALL THERE'S A SMALL 

6909
04:17:20,600 --> 04:17:23,120
REDUCTION IN DEPRESSIVE SYMPTOMS

6910
04:17:23,120 --> 04:17:27,160
AMONG PEOPLE WHO LIVE IN AREAS 

6911
04:17:27,160 --> 04:17:32,640
WITH MORE TREE CANOPY AND WHAT'S

6912
04:17:32,640 --> 04:17:35,800
INTERESTING HERE IS THE 

6913
04:17:35,800 --> 04:17:36,720
ASSOCIATIONS WERE FAR STRONGER 

6914
04:17:36,720 --> 04:17:38,080
AMONG WOMEN WHO LIVED IN 

6915
04:17:38,080 --> 04:17:39,400
NEIGHBORHOODS WHO WERE 

6916
04:17:39,400 --> 04:17:43,320
HISTORICALLY RED LINED 

6917
04:17:43,320 --> 04:17:46,480
SUGGESTING A SMALL INVESTMENT IN

6918
04:17:46,480 --> 04:17:48,440
GREENERY AND THESE HISTORICALLY 

6919
04:17:48,440 --> 04:17:49,760
RED LINED NEIGHBORHOODS MAYBE 

6920
04:17:49,760 --> 04:17:55,160
BENEFICIAL FOR HEALTH.

6921
04:17:55,160 --> 04:17:57,040
I HOPE I'VE CONVINCED YOU 

6922
04:17:57,040 --> 04:17:59,240
PROSPECTIVE COHORT STUDIES ARE 

6923
04:17:59,240 --> 04:18:01,200
IMPORTANT FOR STUDYING 

6924
04:18:01,200 --> 04:18:01,800
ENVIRONMENTAL EXPOSURES IN 

6925
04:18:01,800 --> 04:18:02,880
RELATION TO HEALTH OUTCOMES.

6926
04:18:02,880 --> 04:18:05,280
I THINK ONE THING THAT'S NEEDED 

6927
04:18:05,280 --> 04:18:07,440
FOR THE FUTURE IS MORE DIVERSE 

6928
04:18:07,440 --> 04:18:07,680
COHORTS.

6929
04:18:07,680 --> 04:18:11,960
THE NEW TECHNOLOGIES THAT ARE 

6930
04:18:11,960 --> 04:18:14,840
AVAILABLE HAVE EXPANDED OPTION 

6931
04:18:14,840 --> 04:18:16,040
FOR EXPOSURE ASSESSMENT AND I 

6932
04:18:16,040 --> 04:18:17,360
WANT TO REMIND QUESTIONNAIRES 

6933
04:18:17,360 --> 04:18:19,480
ARE THE BEST WAY TO CAPTURE 

6934
04:18:19,480 --> 04:18:21,320
PERSONAL OR HISTORICAL EXPOSURES

6935
04:18:21,320 --> 04:18:23,720
BUT WHERE POSSIBLE WE NEED TO BE

6936
04:18:23,720 --> 04:18:25,200
VALIDATING THESE MEASURES WITH 

6937
04:18:25,200 --> 04:18:26,360
G.I.S. DATA AND MONITORING BIO 

6938
04:18:26,360 --> 04:18:28,160
MARKER STUDIES.

6939
04:18:28,160 --> 04:18:30,560
STUDYING THE IMPACTS OF MULTIPLE

6940
04:18:30,560 --> 04:18:34,240
EXPOSURES TOGETHER IS 

6941
04:18:34,240 --> 04:18:36,080
INCREASINGLY OF INTEREST.

6942
04:18:36,080 --> 04:18:38,240
CHEMICAL MIXTURES ARE IMPORTANTA

6943
04:18:38,240 --> 04:18:40,120
AS WELL AS THE EXTERNAL AND 

6944
04:18:40,120 --> 04:18:41,080
INTERNAL EXPOSOME.

6945
04:18:41,080 --> 04:18:47,040
WE DON'T WANT TO OVERLOOK THE 

6946
04:18:47,040 --> 04:18:49,800
SOCIAL AND COMMUNITY ENVIRO

6947
04:18:49,800 --> 04:18:50,080
ENVIRONMENT.

6948
04:18:50,080 --> 04:18:51,360
WE'VE ALSO STARTED TO IN OUR 

6949
04:18:51,360 --> 04:18:54,000
STUDY AND THIS IS ESPECIALLY 

6950
04:18:54,000 --> 04:18:55,200
IMPORTANT IN THE TRENDS FOR 

6951
04:18:55,200 --> 04:18:59,760
BREAST CANCER TO FOCUS ON HEALTH

6952
04:18:59,760 --> 04:19:02,280
DISPARITIES IN RELATION TO BOTH 

6953
04:19:02,280 --> 04:19:02,920
THE EXPOSURE OPPORTUNITIES AND 

6954
04:19:02,920 --> 04:19:04,040
DISEASE RISKS.

6955
04:19:04,040 --> 04:19:07,400
AGAIN, I WANT TO MENTION WE NEED

6956
04:19:07,400 --> 04:19:09,240
TO BE INCREASINGLY FOCUSSED ON 

6957
04:19:09,240 --> 04:19:10,240
AFFECTS OF CLIMATE CHANGE WHICH 

6958
04:19:10,240 --> 04:19:12,440
IS SOMETHING WE'RE DOING NOW IN 

6959
04:19:12,440 --> 04:19:13,400
OUR STUDY.

6960
04:19:13,400 --> 04:19:14,960
SO SORRY I WENT A LITTLE BIT 

6961
04:19:14,960 --> 04:19:15,480
OVER AND GLAD TO TAKE ANY 

6962
04:19:15,480 --> 04:19:18,360
QUESTIONS.

6963
04:19:18,360 --> 04:19:19,600
>>THANK YOU, SO MUCH, 

6964
04:19:19,600 --> 04:19:20,800
DR. SANDLER.

6965
04:19:20,800 --> 04:19:22,400
WHAT WE'LL DO NOW IS TURN IT 

6966
04:19:22,400 --> 04:19:25,440
OVER TO DR. QUAKER HARMON WHO 

6967
04:19:25,440 --> 04:19:26,120
WILL PROVIDE ADDITIONAL 

6968
04:19:26,120 --> 04:19:26,760
RECOMMENDATIONS BASED ON OUR 

6969
04:19:26,760 --> 04:19:28,600
TALKS AND SET THE STAGE FOR THE 

6970
04:19:28,600 --> 04:19:31,760
Q&A SESSION.

6971
04:19:31,760 --> 04:19:32,600
DR. HARMON.

6972
04:19:32,600 --> 04:19:38,720
>>THANK YOU.

6973
04:19:38,720 --> 04:19:40,200
SO BEFORE WE IDENTIFY 

6974
04:19:40,200 --> 04:19:41,320
RECOMMENDATIONS, WE'D LIKE TO 

6975
04:19:41,320 --> 04:19:42,720
PROVIDE A BRIEF OVERVIEW OF THE 

6976
04:19:42,720 --> 04:19:44,160
OUTCOMES WE DISCUSSED TODAY AND 

6977
04:19:44,160 --> 04:19:45,400
HOW IMPORTANT DIFFERENCES IN 

6978
04:19:45,400 --> 04:19:47,080
THESE OUTCOMES RELATE TO OUR 

6979
04:19:47,080 --> 04:19:48,320
ABILITY TO STUDY ENVIRONMENTAL 

6980
04:19:48,320 --> 04:19:51,160
EXPOSURES.

6981
04:19:51,160 --> 04:19:54,400
SO STARTING WITH ENDOMETRIOSIS, 

6982
04:19:54,400 --> 04:19:55,160
THERE ARE REALLY IMPORTANT 

6983
04:19:55,160 --> 04:19:57,680
CHALLENGES IN DIAGNOSES WHICH 

6984
04:19:57,680 --> 04:19:59,480
CURRENTLY REQUIRE SURGERY AND 

6985
04:19:59,480 --> 04:20:01,280
THIS MAKES IT DIFFICULT TO STUDY

6986
04:20:01,280 --> 04:20:02,360
ENDOMETRIOSIS IN POPULATIONS.

6987
04:20:02,360 --> 04:20:04,600
AND GIVEN THIS DIFFICULTY, WE 

6988
04:20:04,600 --> 04:20:06,880
STILL DON'T KNOW MUCH ABOUT 

6989
04:20:06,880 --> 04:20:07,840
ENDOMETRIOSIS AND IN FACT WHEN 

6990
04:20:07,840 --> 04:20:13,680
WE SEARCH PUB MED WE FOUND FEWER

6991
04:20:13,680 --> 04:20:15,920
THAN 3,000 PUBLICATIONS AND MANY

6992
04:20:15,920 --> 04:20:18,040
PEOPLE DON'T KNOW ABOUT 

6993
04:20:18,040 --> 04:20:19,000
ENDOMETRIOSIS AS A HEALTH 

6994
04:20:19,000 --> 04:20:19,240
OUTCOME.

6995
04:20:19,240 --> 04:20:21,360
THERE'S A RIBBON CAMPAIGN TO 

6996
04:20:21,360 --> 04:20:23,520
RAISE AWARENESS AND RESEARCH 

6997
04:20:23,520 --> 04:20:25,240
FUNDS BUT IT'S NOT A HIGH 

6998
04:20:25,240 --> 04:20:26,280
PROFILE CONDITION AND GIVEN HOW 

6999
04:20:26,280 --> 04:20:27,400
MUCH WE DON'T KNOW ABOUT 

7000
04:20:27,400 --> 04:20:28,680
ENDOMETRIOSIS AND THE DIFFICULTY

7001
04:20:28,680 --> 04:20:31,040
IN MAKING A DIAGNOSIS IT BECOMES

7002
04:20:31,040 --> 04:20:32,400
VERY CHALLENGING TO STUDY 

7003
04:20:32,400 --> 04:20:36,320
ENVIRONMENTAL EXPOSURES.

7004
04:20:36,320 --> 04:20:40,040
UTERINE FIBROIDS INVOLVE OUR 

7005
04:20:40,040 --> 04:20:41,320
NEXT STAGE OF PROGRESSION IN 

7006
04:20:41,320 --> 04:20:42,760
TERMS OF KNOWLEDGE.

7007
04:20:42,760 --> 04:20:47,200
WE CAN USE ULTRASOUND AND 

7008
04:20:47,200 --> 04:20:48,240
STUDIES SUCH AS SELF ARE 

7009
04:20:48,240 --> 04:20:51,400
POSSIBLE BUT THE ABILITY TO 

7010
04:20:51,400 --> 04:20:54,680
DIAGNOSE FIBROIDS HAS BEEN 

7011
04:20:54,680 --> 04:20:55,640
SLOWLY TRANSLATED TO HOW MUCH IS

7012
04:20:55,640 --> 04:20:58,120
KNOWN AND WE FOUND FEWER THAN 

7013
04:20:58,120 --> 04:21:00,600
2,000 SCIENTIFIC PUBLICATIONS.

7014
04:21:00,600 --> 04:21:01,800
FIBROIDS THOUGH COMMON HAVE VERY

7015
04:21:01,800 --> 04:21:02,840
LOW PUBLIC AWARENESS.

7016
04:21:02,840 --> 04:21:04,840
I WAS UNABLE TO FIND A RIBBON 

7017
04:21:04,840 --> 04:21:07,120
CAMPAIGN FOR FIBROIDS.

7018
04:21:07,120 --> 04:21:08,600
HOWEVER, THERE ARE INCREASING 

7019
04:21:08,600 --> 04:21:09,800
PUBLIC AWARENESS AND SUPPORT 

7020
04:21:09,800 --> 04:21:13,440
GROUPS AND HERE I'M HIGHLIGHTING

7021
04:21:13,440 --> 04:21:15,760
THE WHITE DRESS PROJECT.

7022
04:21:15,760 --> 04:21:18,080
AS WE LEARN MORE ABOUT THE 

7023
04:21:18,080 --> 04:21:19,800
NATURAL HISTORY OF FIBROIDS IT 

7024
04:21:19,800 --> 04:21:23,200
BECOMES EASIER TO IDENTIFY 

7025
04:21:23,200 --> 04:21:23,760
IMPORTANT ENVIRONMENTAL 

7026
04:21:23,760 --> 04:21:24,800
EXPOSURES BUT WE MUST PRIORITIZE

7027
04:21:24,800 --> 04:21:27,760
STRONG STUDY DESIGNS.

7028
04:21:27,760 --> 04:21:29,880
BREAST CANCER REPRESENTS AN 

7029
04:21:29,880 --> 04:21:32,600
OUTCOME WHERE THE SCIENCE HAS 

7030
04:21:32,600 --> 04:21:34,120
ADVANCED AND THE KNOWLEDGE ABOUT

7031
04:21:34,120 --> 04:21:35,880
THE RISK FACTORS FOR BREAST 

7032
04:21:35,880 --> 04:21:39,720
CANCER HAS BEEN TRANSLATED TO A 

7033
04:21:39,720 --> 04:21:40,720
ROBUST SCREENING PROGRAM AND THE

7034
04:21:40,720 --> 04:21:42,280
SISTER STUDY WHICH RECRUITED 

7035
04:21:42,280 --> 04:21:43,920
WOMEN BASED ON FAMILY HISTORY.

7036
04:21:43,920 --> 04:21:45,560
BREAST CANCER HAS MORE THAN 

7037
04:21:45,560 --> 04:21:47,080
40,000 PUBLICATIONS REPRESENTING

7038
04:21:47,080 --> 04:21:49,560
AN EXTENSIVE RESEARCH PROGRAM.

7039
04:21:49,560 --> 04:21:52,520
BREAST CANCER HAS A WIDELY 

7040
04:21:52,520 --> 04:21:54,840
RECOGNIZED RIBBON CAMPAIGN AND 

7041
04:21:54,840 --> 04:21:56,600
AN AWARENESS MONTH WE'RE IN 

7042
04:21:56,600 --> 04:21:58,120
RIGHT NOW AND THE HISTORY AND 

7043
04:21:58,120 --> 04:21:59,720
PRESENCE OF A ROBUST SCREENING 

7044
04:21:59,720 --> 04:22:01,880
AND REPORTING SYSTEM MAKES IT 

7045
04:22:01,880 --> 04:22:03,840
LESS CHALLENGING TO STUDY THE 

7046
04:22:03,840 --> 04:22:04,560
EFFECTS OF ENVIRONMENTAL 

7047
04:22:04,560 --> 04:22:04,840
EXPOSURES.

7048
04:22:04,840 --> 04:22:06,680
SO AS YOU THINK OF WAYS TO 

7049
04:22:06,680 --> 04:22:08,600
ADVANCE SCIENCE ON THE 

7050
04:22:08,600 --> 04:22:10,000
ENVIRONMENTAL IMPACTS OF WOMEN'S

7051
04:22:10,000 --> 04:22:11,760
HEALTH, SOLUTIONS WILL VARY 

7052
04:22:11,760 --> 04:22:12,880
DEPENDING ON WHERE ON THE 

7053
04:22:12,880 --> 04:22:16,520
SPECTRUM A CONDITION FALLS.

7054
04:22:16,520 --> 04:22:18,000
AND THE DIFFERENCES IN THE STATE

7055
04:22:18,000 --> 04:22:19,360
OF KNOWLEDGE ARE REFLECTED IN 

7056
04:22:19,360 --> 04:22:21,560
THE FUND OF THE OUTCOMES.

7057
04:22:21,560 --> 04:22:24,200
DR. CHANDLER AT NSU PLOTTED DATA

7058
04:22:24,200 --> 04:22:28,000
FROM A 2019 PUBLICATION SHOWING 

7059
04:22:28,000 --> 04:22:29,400
THAT FEMALE DOMINATED CONDITIONS

7060
04:22:29,400 --> 04:22:32,080
IN RED ARE OFTEN UNDER FUNDED 

7061
04:22:32,080 --> 04:22:33,720
COMPARED TO MALE DOMINATED 

7062
04:22:33,720 --> 04:22:35,560
OUTCOMES IN BLUE WHICH HAVE 

7063
04:22:35,560 --> 04:22:38,160
SIMILAR DISEASE BURDEN.

7064
04:22:38,160 --> 04:22:39,840
ENDOMETRIOSIS AND FIBROIDS IN 

7065
04:22:39,840 --> 04:22:41,280
PARTICULAR HAVE LOW FUNDING IN 

7066
04:22:41,280 --> 04:22:43,680
RELATION TO THEIR DISEASE 

7067
04:22:43,680 --> 04:22:43,880
BURDEN.

7068
04:22:43,880 --> 04:22:46,120
SO ONE OF OUR FIRST 

7069
04:22:46,120 --> 04:22:47,640
RECOMMENDATION TO INCREASE THE 

7070
04:22:47,640 --> 04:22:51,000
FOCUS AND FUNDING ON THE 

7071
04:22:51,000 --> 04:22:52,720
NON-FATAL CONDITIONS THAT AFFECT

7072
04:22:52,720 --> 04:22:53,640
QUALITY OF LIFE.

7073
04:22:53,640 --> 04:22:55,960
WE MOSTLY PRESENTED ON 

7074
04:22:55,960 --> 04:22:57,120
CONDITIONS THAT ARE EXCLUSIVELY 

7075
04:22:57,120 --> 04:22:59,160
SEEN IN WOMEN, THERE ARE OTHER 

7076
04:22:59,160 --> 04:22:59,800
IMPORTANT CONDITIONS TO 

7077
04:22:59,800 --> 04:23:00,040
CONSIDER.

7078
04:23:00,040 --> 04:23:02,400
AMONG THE TOP CAUSES OF IN 

7079
04:23:02,400 --> 04:23:04,440
FEMALES, HEART DISEASE AND 

7080
04:23:04,440 --> 04:23:05,880
CANCER MAY HAVE DIFFERENT AND 

7081
04:23:05,880 --> 04:23:09,240
UNIQUE RISK FACTORS AND CLINICAL

7082
04:23:09,240 --> 04:23:09,560
PRESENTATIONS.

7083
04:23:09,560 --> 04:23:13,080
THE NEXT CAUSES OF DEATH, 

7084
04:23:13,080 --> 04:23:14,720
STROKE, ALZHEIMER'S AND CHRONIC 

7085
04:23:14,720 --> 04:23:16,880
RESPIRATORY DISEASE ARE MORE 

7086
04:23:16,880 --> 04:23:18,080
COMMON IN FEMALES COMPARED TO 

7087
04:23:18,080 --> 04:23:19,080
MALES AND STUDIES NEED TO 

7088
04:23:19,080 --> 04:23:21,360
INCLUDE MORE WOMEN AND 

7089
04:23:21,360 --> 04:23:22,000
IMPORTANTLY ADDRESS EXPOSURES 

7090
04:23:22,000 --> 04:23:24,600
THAT MAY BE UNIQUE OR MORE 

7091
04:23:24,600 --> 04:23:25,520
COMMON IN WOMEN.

7092
04:23:25,520 --> 04:23:28,560
FOR EXAMPLE, GENDERED AND 

7093
04:23:28,560 --> 04:23:30,960
RACIALIZED BEAUTY STANDARDS 

7094
04:23:30,960 --> 04:23:32,480
RESULT IN DIFFERENCES IN RESULTS

7095
04:23:32,480 --> 04:23:33,600
IN PERSONAL CARE PRODUCTS.

7096
04:23:33,600 --> 04:23:35,600
IN ADDITION TO THESE THREE 

7097
04:23:35,600 --> 04:23:37,000
RECOMMENDATIONS, WE'D LIKE TO 

7098
04:23:37,000 --> 04:23:39,760
HIGHLIGHT THE NEED TO PROMOTE 

7099
04:23:39,760 --> 04:23:41,360
STUDIES WITH STRONG 

7100
04:23:41,360 --> 04:23:42,160
EPIDEMIOLOGIC DESIGNS WHICH WILL

7101
04:23:42,160 --> 04:23:44,000
RESULT IN ROBUST RESULTS.

7102
04:23:44,000 --> 04:23:46,320
THERE'S AN URGENT NEED TO 

7103
04:23:46,320 --> 04:23:48,600
UNDERSTAND THE BASIC 

7104
04:23:48,600 --> 04:23:51,080
EPIDEMIOLOGY OF UNDER STUDIED 

7105
04:23:51,080 --> 04:23:52,000
CONDITIONS TO MAKE PROGRESS ON 

7106
04:23:52,000 --> 04:23:52,640
MAJOR RISK FACTORS.

7107
04:23:52,640 --> 04:23:56,760
SUPPORT FOR THE DEVELOPMENT OF 

7108
04:23:56,760 --> 04:23:59,680
NON-INVASIVE DIAGNOSTIC TOOLS TO

7109
04:23:59,680 --> 04:24:01,680
ADVANCE CLINICAL CARE AND 

7110
04:24:01,680 --> 04:24:02,120
RESEARCH.

7111
04:24:02,120 --> 04:24:03,480
MANY CONDITIONS DEVELOP OVER THE

7112
04:24:03,480 --> 04:24:05,320
LIFE COURSE AND LIFE COURSE 

7113
04:24:05,320 --> 04:24:07,360
STUDIES REQUIRE INNOVATION AND 

7114
04:24:07,360 --> 04:24:09,400
UNIQUE FUNDING MECHANISMS.

7115
04:24:09,400 --> 04:24:11,840
WOMEN FACE IMPORTANT AND UNIQUE 

7116
04:24:11,840 --> 04:24:12,520
SOCIAL DETERMINATES OF HEALTH 

7117
04:24:12,520 --> 04:24:14,560
WHICH INFLUENCE THEIR EXPOSURES.

7118
04:24:14,560 --> 04:24:16,000
THESE SOCIAL DETERMINATES MUST 

7119
04:24:16,000 --> 04:24:17,640
BE MEASURED IN ANY STUDY OF 

7120
04:24:17,640 --> 04:24:18,720
OTHER RISK FACTORS.

7121
04:24:18,720 --> 04:24:21,120
AND ALL OF THIS IS ONLY POSSIBLE

7122
04:24:21,120 --> 04:24:24,600
USING TEAM SCIENCE APPROACHES 

7123
04:24:24,600 --> 04:24:26,480
WHICH NECESSITATE DIVERSITY AND 

7124
04:24:26,480 --> 04:24:27,360
SCIENTIFIC EXPERTISE AND LIVED 

7125
04:24:27,360 --> 04:24:31,720
EXPERIENCES.

7126
04:24:31,720 --> 04:24:32,920
>>THANK YOU.

7127
04:24:32,920 --> 04:24:36,360
I'LL NOW TURN IT OVER TO 

7128
04:24:36,360 --> 04:24:39,400
DR. REGINE DOUTHARD TO MODERATE 

7129
04:24:39,400 --> 04:24:43,600
OUR Q&A.

7130
04:24:43,600 --> 04:24:46,120
>>I WANT TO THANK ALL OF
OUR 

7131
04:24:46,120 --> 04:24:49,520
PANELISTS FOR INVISIGHTFUL 

7132
04:24:49,520 --> 04:24:49,840
PRESENTATION.

7133
04:24:49,840 --> 04:24:53,080
ALL THE PRESENTATIONS AND NOW 

7134
04:24:53,080 --> 04:24:56,320
I'LL TRANSITION TO THE Q&A 

7135
04:24:56,320 --> 04:24:56,880
SESSION.

7136
04:24:56,880 --> 04:25:01,800
PLEASE INCLUDE YOUR QUESTIONS IN

7137
04:25:01,800 --> 04:25:05,520
THE CHAT BOX AND TO WHICH 

7138
04:25:05,520 --> 04:25:06,720
PANELIST THE QUESTION IS 

7139
04:25:06,720 --> 04:25:08,040
ADDRESSED AND YOU CAN ALSO RAISE

7140
04:25:08,040 --> 04:25:13,760
YOUR HAND AND INVITE TO YOU ASK 

7141
04:25:13,760 --> 04:25:15,640
YOUR QUESTION.

7142
04:25:15,640 --> 04:25:18,440
I DON'T SEE ANY HAND RAISED -- 

7143
04:25:18,440 --> 04:25:19,400
>>DR. SIMON HAD A
QUESTION IN 

7144
04:25:19,400 --> 04:25:25,240
THE CHAT.

7145
04:25:25,240 --> 04:25:30,280
DR. SIMON, WOULD YOU LIKE TO 

7146
04:25:30,280 --> 04:25:35,320
STATE YOUR QUESTION AND IF YOU 

7147
04:25:35,320 --> 04:25:37,120
DON'T MIND?

7148
04:25:37,120 --> 04:25:43,200
>>I WAS WONDERING WHEN A 

7149
04:25:43,200 --> 04:25:47,600
PRESENTER WAS TALKING ABOUT 

7150
04:25:47,600 --> 04:25:51,000
PROGESTERONE AND INSTEAD OF A 

7151
04:25:51,000 --> 04:25:55,000
REFORMATION FOR PROGESTERONE FOR

7152
04:25:55,000 --> 04:25:57,840
CONTRACEPTION PERHAPS IS 

7153
04:25:57,840 --> 04:26:02,280
REINVIGORATING THE OTHER 

7154
04:26:02,280 --> 04:26:02,880
RESEARCH.

7155
04:26:02,880 --> 04:26:05,960
AND MY SECOND QUESTION I HAVEN'T

7156
04:26:05,960 --> 04:26:08,600
HEARD MUCH ABOUT STRUCTURAL 

7157
04:26:08,600 --> 04:26:15,160
RACISM AND HOW THAT 

7158
04:26:15,160 --> 04:26:16,560
NEIGHBORHOODS WERE CREATED AND 

7159
04:26:16,560 --> 04:26:18,800
GET HIGHER LEVELS OF THE 

7160
04:26:18,800 --> 04:26:22,000
ENVIRONMENTAL EXPOSURES REALLY 

7161
04:26:22,000 --> 04:26:23,280
DRIVES A LOT OF THE RESEARCH AND

7162
04:26:23,280 --> 04:26:27,400
I'D LIKE TO SEE THE ADDITIONAL 

7163
04:26:27,400 --> 04:26:29,920
ELEMENT ADDED TO FUTURE RESEARCH

7164
04:26:29,920 --> 04:26:31,880
AND THAT DOES INCLUDE WHAT WAS 

7165
04:26:31,880 --> 04:26:33,400
SAID AT THE LAST RECOMMENDATION 

7166
04:26:33,400 --> 04:26:36,840
AND TEAM SCIENCE AND TRANS 

7167
04:26:36,840 --> 04:26:37,640
DISCIPLINARY EQUITY RESEARCHERS 

7168
04:26:37,640 --> 04:26:47,960
GETTING ON BOARD.

7169
04:26:49,480 --> 04:26:58,880
>>WE WERE ONLY ABLE TO
LOOK AT 

7170
04:26:58,880 --> 04:26:59,240
DEPRO-PROVERA.

7171
04:26:59,240 --> 04:27:01,280
WE'RE CURRENTLY LOOKING AT THE 

7172
04:27:01,280 --> 04:27:07,680
USE OF HORMONAL IUDs IN FIBROID 

7173
04:27:07,680 --> 04:27:07,960
DEVELOPMENT.

7174
04:27:07,960 --> 04:27:12,600
IT LOOKS LIKE SOME ARE SWITCHING

7175
04:27:12,600 --> 04:27:14,360
TO THE USE OF THIS CONTRACEPTION

7176
04:27:14,360 --> 04:27:16,600
AND WE'RE WONDERING IF IT IS 

7177
04:27:16,600 --> 04:27:20,320
ALSO ASSOCIATED WITH FIBROID 

7178
04:27:20,320 --> 04:27:22,080
INCIDENTS AND GROWTH AND WE'LL 

7179
04:27:22,080 --> 04:27:23,880
BE REPORTING THOSE RESULTS WHEN 

7180
04:27:23,880 --> 04:27:26,720
IT IS DONE.

7181
04:27:26,720 --> 04:27:29,040
WE CERTAINLY AGREE WITH THE 

7182
04:27:29,040 --> 04:27:34,080
ISSUES OF STRUCTURAL RACISM.

7183
04:27:34,080 --> 04:27:37,440
IN SELF WE'RE CHALLENGED BECAUSE

7184
04:27:37,440 --> 04:27:40,600
WE'RE NOT LOOKING AT A 

7185
04:27:40,600 --> 04:27:42,000
HOMOGENOUS POPULATION BUT 

7186
04:27:42,000 --> 04:27:43,760
CONSTRAINED POPULATION WITHIN 

7187
04:27:43,760 --> 04:27:48,000
DETROIT AND THE ISSUES BLACK 

7188
04:27:48,000 --> 04:27:49,320
WOMEN IN PARTICULAR IN DETROIT 

7189
04:27:49,320 --> 04:27:50,440
MAY BE DIFFERENT THAN OTHER 

7190
04:27:50,440 --> 04:27:53,880
PARTS OF THE COUNTRY.

7191
04:27:53,880 --> 04:27:56,760
IT'S CERTAINLY A PRIORITY AT 

7192
04:27:56,760 --> 04:27:59,000
NIEHS TO START INCREASING 

7193
04:27:59,000 --> 04:27:59,680
FUNDING IN THE SOCIAL 

7194
04:27:59,680 --> 04:28:00,600
DETERMINATES OF HEALTH AND 

7195
04:28:00,600 --> 04:28:02,440
THINKING HOW TO MEASURE AND HOW 

7196
04:28:02,440 --> 04:28:04,600
TO INCLUDE MEASURES OF 

7197
04:28:04,600 --> 04:28:06,720
STRUCTURAL RACISM INTO STUDIES 

7198
04:28:06,720 --> 04:28:07,480
OF THE ENVIRONMENT.

7199
04:28:07,480 --> 04:28:13,280
>>I'D LIKE TO ADD
SOMETHING TO 

7200
04:28:13,280 --> 04:28:18,320
THAT.

7201
04:28:18,320 --> 04:28:25,000
AND STUDIES NEED TO INCREASINGLY

7202
04:28:25,000 --> 04:28:27,400
STRUCTURAL RACISM AND WHEN WE 

7203
04:28:27,400 --> 04:28:28,560
LOOK AT A SOCIAL ENVIRONMENT 

7204
04:28:28,560 --> 04:28:30,760
MEASURE BASED ON SOCIO ECONOMIC 

7205
04:28:30,760 --> 04:28:32,400
FACTORS WHAT WE'RE CONSIDERED IS

7206
04:28:32,400 --> 04:28:36,600
WHAT ARE THE LONG-TERM 

7207
04:28:36,600 --> 04:28:38,000
IMPLICATIONS FROM HISTORICAL AND

7208
04:28:38,000 --> 04:28:39,400
CURRENT STRUCTURAL RACISM.

7209
04:28:39,400 --> 04:28:42,640
PEOPLE WHO LIVE IN NEIGHBORHOODS

7210
04:28:42,640 --> 04:28:48,880
THAT ARE UNDER RESOURCED AND 

7211
04:28:48,880 --> 04:28:51,320
LOOKING AT ENVIRONMENTAL 

7212
04:28:51,320 --> 04:28:51,680
CONTAMINATES.

7213
04:28:51,680 --> 04:28:52,720
IT NEEDS TO BE CONSIDERED IN 

7214
04:28:52,720 --> 04:28:56,560
EVERYTHING WE DO.

7215
04:28:56,560 --> 04:29:07,080
WE STARTED TO DO THIS AND ARE 

7216
04:29:07,680 --> 04:29:09,720
LOOKING AT MORE.

7217
04:29:09,720 --> 04:29:14,000
>>WE HAVE ANOTHER
QUESTION.

7218
04:29:14,000 --> 04:29:16,000
CAN YOU COMMENT ON THE 

7219
04:29:16,000 --> 04:29:17,360
ASSOCIATION BETWEEN 

7220
04:29:17,360 --> 04:29:19,600
ENDOCRINE-DISRUPTING CHEMICALS 

7221
04:29:19,600 --> 04:29:20,600
AND OTHER ENVIRONMENTAL 

7222
04:29:20,600 --> 04:29:24,920
EXPOSURES AND HORMONAL 

7223
04:29:24,920 --> 04:29:25,640
CONTRACEPTION.

7224
04:29:25,640 --> 04:29:27,320
MOST PREMENOPAUSAL WOMEN HAVE 

7225
04:29:27,320 --> 04:29:30,400
USED HORMONE CONTRACEPTION AND 

7226
04:29:30,400 --> 04:29:36,560
IT ALSO CONFERS ANDI RISK AND 

7227
04:29:36,560 --> 04:29:39,240
ASSOCIATED WITH ENDOMETRIOSIS 

7228
04:29:39,240 --> 04:29:40,520
AND FIBROIDS AND BREAST CANCER.

7229
04:29:40,520 --> 04:29:43,040
>>I'M HAPPY DIVE IN AND
TALK 

7230
04:29:43,040 --> 04:29:44,840
ABOUT HORMONAL CONTRACEPTIVE AND

7231
04:29:44,840 --> 04:29:45,640
ENVIRONMENTAL EXPOSURE.

7232
04:29:45,640 --> 04:29:48,040
I PUBLISHED A PAPER IN 

7233
04:29:48,040 --> 04:29:48,600
ENVIRONMENTAL HEALTH 

7234
04:29:48,600 --> 04:29:52,280
PERSPECTIVES WITHIN THE SELF 

7235
04:29:52,280 --> 04:29:56,880
COHORT LOOKING AT THE USE OF 

7236
04:29:56,880 --> 04:30:02,720
DEPRO-PROVERA AND WE KNOW THAT 

7237
04:30:02,720 --> 04:30:06,720
DEPRO CAN CONFER SKELETAL 

7238
04:30:06,720 --> 04:30:08,600
EFFECTS AND IT'S STORED IN OUR 

7239
04:30:08,600 --> 04:30:10,840
SKELETON WITH THE INCREASED BONE

7240
04:30:10,840 --> 04:30:13,800
TURNOVER AND LOSS OF DENSITY WE 

7241
04:30:13,800 --> 04:30:16,600
HAVE A CONTROVERSY OF WHAT WAS 

7242
04:30:16,600 --> 04:30:18,960
STORED IN BONE BEING SENT INTO 

7243
04:30:18,960 --> 04:30:21,920
THE CIRCULATING SYSTEM AND 

7244
04:30:21,920 --> 04:30:24,360
CIRCULATING INTO ORGANS.

7245
04:30:24,360 --> 04:30:26,440
THAT'S BEEN MY WORK LOOKING 

7246
04:30:26,440 --> 04:30:27,440
WITHIN HORMONAL CONTRACEPTIVE 

7247
04:30:27,440 --> 04:30:32,440
AND THINKING THROUGH THE BONE 

7248
04:30:32,440 --> 04:30:42,200
PATHWAY WITH THAT REGARD.

7249
04:30:42,200 --> 04:30:43,600
>>I THINK WE HAVE ONE
MINUTE 

7250
04:30:43,600 --> 04:30:43,800
LEFT.

7251
04:30:43,800 --> 04:30:44,920
I DON'T SEE ANOTHER QUESTION IN 

7252
04:30:44,920 --> 04:30:50,880
THE CHAT BOX SO MAYBE I CAN AND 

7253
04:30:50,880 --> 04:30:52,920
CAN I ASK ONE LAST QUESTION?

7254
04:30:52,920 --> 04:30:59,080
>>GO AHEAD, REGINE, TAKE 

7255
04:30:59,080 --> 04:30:59,920
ANOTHER TWO MINUTES.

7256
04:30:59,920 --> 04:31:01,360
>>YOU SHED INFORMATION ON
THE 

7257
04:31:01,360 --> 04:31:03,560
FUNDING STUDIES OF 

7258
04:31:03,560 --> 04:31:04,280
FEMALE-DOMINANT CONDITIONS.

7259
04:31:04,280 --> 04:31:07,720
WHAT DO YOU THINK HAVE BEEN THE 

7260
04:31:07,720 --> 04:31:09,000
BARRIERS TO FUNDING AND THAT'S 

7261
04:31:09,000 --> 04:31:19,400
TO ALL OF OUR PANELISTS.

7262
04:31:20,640 --> 04:31:20,720
 

7263
04:31:20,720 --> 04:31:25,000
>>FINDING A STUDY SECTION
WITH 

7264
04:31:25,000 --> 04:31:27,440
THE EPIDEMIOLOGIC EXPERTISE AND 

7265
04:31:27,440 --> 04:31:28,960
THE INTEREST AND EXPERTISE IN 

7266
04:31:28,960 --> 04:31:32,520
PARTICULAR WOMEN'S HEALTH 

7267
04:31:32,520 --> 04:31:32,800
OUTCOMES.

7268
04:31:32,800 --> 04:31:35,800
I THINK THAT HAS BEEN A BARRIER 

7269
04:31:35,800 --> 04:31:41,760
IS FINDING A HOME FOR THE 

7270
04:31:41,760 --> 04:31:44,320
STUDIES AND FINDING STUDY 

7271
04:31:44,320 --> 04:31:45,600
SECTIONS INTERESTED AND CAPABLE 

7272
04:31:45,600 --> 04:31:47,080
OF EVALUATING AND FINDING THE 

7273
04:31:47,080 --> 04:31:47,840
BEST STUDIES.

7274
04:31:47,840 --> 04:31:49,560
>>AND I WOULD LIKE TO
FURTHER 

7275
04:31:49,560 --> 04:31:52,400
ADD, I THINK HISTORICALLY WE'VE 

7276
04:31:52,400 --> 04:31:53,640
HAD AN ISSUE WHERE WOMEN 

7277
04:31:53,640 --> 04:31:56,600
PRESENTING WITH HEAVY MENSTRUAL 

7278
04:31:56,600 --> 04:32:00,600
BLEEDING AND MENSTRUAL PAIN HAVE

7279
04:32:00,600 --> 04:32:04,000
BEEN DISMISSED IN THE CLINICAL 

7280
04:32:04,000 --> 04:32:06,960
SETTING HISTORICALLY AND HAVING 

7281
04:32:06,960 --> 04:32:07,680
DISMISSED IN TERMS OF HAVING 

7282
04:32:07,680 --> 04:32:11,360
PERIODS AND HAVING A GREATER 

7283
04:32:11,360 --> 04:32:13,320
AWARENESS THE DISRUPTION OF 

7284
04:32:13,320 --> 04:32:14,040
HEAVY MENSTRUAL BLEEDING AND 

7285
04:32:14,040 --> 04:32:15,920
PAIN IN THE ACTIVITIES OF DAILY 

7286
04:32:15,920 --> 04:32:17,720
LIVING WARRANT THE IMPORTANCE OF

7287
04:32:17,720 --> 04:32:18,800
THINKING ABOUT THESE CONDITIONS 

7288
04:32:18,800 --> 04:32:24,400
IN TERMS OF QUALITY OF LIFE AND 

7289
04:32:24,400 --> 04:32:25,240
WARRANTS FUNDING INTO THESE 

7290
04:32:25,240 --> 04:32:25,560
CONDITIONS.

7291
04:32:25,560 --> 04:32:27,200
>>THANK YOU VERY MUCH.

7292
04:32:27,200 --> 04:32:29,840
SO NOW THAT WE REACHED THE END 

7293
04:32:29,840 --> 04:32:31,120
OF THE Q&A SESSION SO PLEASE

7294
04:32:31,120 --> 04:32:36,600
JOIN ME IN THANKING ALL OF OUR 

7295
04:32:36,600 --> 04:32:39,440
PANELISTS, DR. UPSON, DR. HARMON

7296
04:32:39,440 --> 04:32:42,840
AND SANDLER FOR THEIR 

7297
04:32:42,840 --> 04:32:43,880
PARTICIPATION AND INFORMATIVE 

7298
04:32:43,880 --> 04:32:45,600
PRESENTATIONS AND ENRICHING 

7299
04:32:45,600 --> 04:32:53,840
DISCUSSION THIS AFTERNOON.

7300
04:32:53,840 --> 04:32:57,760
I'LL TURN IT TO DR. NOURSI.

7301
04:32:57,760 --> 04:32:59,600
>>THANK YOU, DR. DOUTHARD
AND 

7302
04:32:59,600 --> 04:33:00,680
TO ALL THE PRESENTERS.

7303
04:33:00,680 --> 04:33:02,600
I'D LIKE TO GO TO THE NEXT 

7304
04:33:02,600 --> 04:33:04,960
SESSION AND FOR THIS ONE I WILL 

7305
04:33:04,960 --> 04:33:07,440
PUT ON MY HAT AS THE ASSOCIATE 

7306
04:33:07,440 --> 04:33:09,960
DIRECTOR FOR SCIENCE POLICY, 

7307
04:33:09,960 --> 04:33:11,600
PLANNING AND ANALYSIS AT ORWH.

7308
04:33:11,600 --> 04:33:15,920
I WOULD LIKE TO INTRODUCE FOR 

7309
04:33:15,920 --> 04:33:17,720
THIS SESSION TWO OF MY 

7310
04:33:17,720 --> 04:33:20,120
COLLEAGUES WHO WILL BE 

7311
04:33:20,120 --> 04:33:21,920
PRESENTING WITH ME.

7312
04:33:21,920 --> 04:33:26,680
DOCTORS KELLY CHANDLER AND 

7313
04:33:26,680 --> 04:33:29,280
DR. CHING-YI PRESENTING THE NEXT

7314
04:33:29,280 --> 04:33:30,000
ONE.

7315
04:33:30,000 --> 04:33:31,160
DR. CHANDLER IS THE SECOND HALF 

7316
04:33:31,160 --> 04:33:33,000
OF THE DOCTOR CHANDLER WHO WAS 

7317
04:33:33,000 --> 04:33:34,680
MENTIONED A FEW MINUTES AGO.

7318
04:33:34,680 --> 04:33:38,840
SHE IS A HEALTH SCIENCE POLICY 

7319
04:33:38,840 --> 04:33:39,920
ANALYST AT ORWH.

7320
04:33:39,920 --> 04:33:44,440
SHE COORDINATED THE 

7321
04:33:44,440 --> 04:33:45,040
CONGRESSIONALLY MANDATED 

7322
04:33:45,040 --> 04:33:47,800
DIRECTORS MEETING AND 

7323
04:33:47,800 --> 04:33:48,600
COORDINATES THE STRATEGIC PLAN 

7324
04:33:48,600 --> 04:33:49,880
ON THE HEALTH OF WOMEN AND 

7325
04:33:49,880 --> 04:33:51,760
SUPPORTS EFFORTS RELATED TO 

7326
04:33:51,760 --> 04:33:54,520
SCIENCE POLICY FOR THE HEALTH OF

7327
04:33:54,520 --> 04:33:55,240
WOMEN AT ORWH.

7328
04:33:55,240 --> 04:33:57,560
DR. CHANDLER COMPLETED HER Ph.D.

7329
04:33:57,560 --> 04:34:02,680
IN MOLECULAR PHYSIOLOGY AND BIO 

7330
04:34:02,680 --> 04:34:03,360
PHYSICS AT VANDERBILT UNIVERSITY

7331
04:34:03,360 --> 04:34:06,280
WHERE HER RESEARCH FOCUSSED ON 

7332
04:34:06,280 --> 04:34:12,360
MAPPING ANCIENT LONG RANGE 

7333
04:34:12,360 --> 04:34:15,240
ENHANCERS OF DEVELOPMENTALLY 

7334
04:34:15,240 --> 04:34:16,520
RELATED GENES USING TRANSGENIC 

7335
04:34:16,520 --> 04:34:17,000
MOUSE MODEL.

7336
04:34:17,000 --> 04:34:20,320
SHE COMPLETED A POST-DOCTORAL 

7337
04:34:20,320 --> 04:34:21,480
FELLOWSHIP AT THE 

7338
04:34:21,480 --> 04:34:22,280
U.S. ENVIRONMENTAL PROTECTION 

7339
04:34:22,280 --> 04:34:26,200
AGENCY WHERE SHE WAS A PART OF 

7340
04:34:26,200 --> 04:34:28,560
TOXICAST TEAMS BUILDING 

7341
04:34:28,560 --> 04:34:31,200
PREDICTIVE MODELS OF 

7342
04:34:31,200 --> 04:34:33,520
DEVELOPMENTAL TOXICITY.

7343
04:34:33,520 --> 04:34:34,920
PRIOR TO JOINING ORWH THIS YEAR,

7344
04:34:34,920 --> 04:34:37,960
DR. CHANDLER WAS ENGAGED WITH 

7345
04:34:37,960 --> 04:34:39,480
MULTIPLE STRATEGIC PLANNING AND 

7346
04:34:39,480 --> 04:34:42,000
POLICY EFFORTS ACROSS THE NIH 

7347
04:34:42,000 --> 04:34:44,080
AND HHS AND LED THE 

7348
04:34:44,080 --> 04:34:47,120
INTERPRETATION AND REVIEW OF 

7349
04:34:47,120 --> 04:34:48,280
GOVERNMENT-WIDE REGULATIONS IN 

7350
04:34:48,280 --> 04:34:51,000
THE OFFICE OF POLICY, PLANNING, 

7351
04:34:51,000 --> 04:34:52,240
EVALUATION AT THE NATIONAL 

7352
04:34:52,240 --> 04:34:52,840
INSTITUTE OF ENVIRONMENTAL 

7353
04:34:52,840 --> 04:34:56,840
HEALTH SCIENCES.

7354
04:34:56,840 --> 04:35:02,520
THE SECOND TEAM MEMBER IS 

7355
04:35:02,520 --> 04:35:04,560
DR. CHING-YI SHIEH A HEALTH 

7356
04:35:04,560 --> 04:35:06,160
POLICY ANALYST AND STATISTICIAN 

7357
04:35:06,160 --> 04:35:10,360
WITH ORWH AND HER DUTIES INCLUDE

7358
04:35:10,360 --> 04:35:13,720
RESEARCH METHOD COMPUTATION AND 

7359
04:35:13,720 --> 04:35:14,640
PORTFOLIO ANALYSIS AND 

7360
04:35:14,640 --> 04:35:16,360
CONGRESSIONALLY BUDGET 

7361
04:35:16,360 --> 04:35:16,600
REPORTING.

7362
04:35:16,600 --> 04:35:20,440
SHE ALSO LEADS THE TRANS-NIH 

7363
04:35:20,440 --> 04:35:21,120
MANUAL CATEGORIZATION SYSTEM 

7364
04:35:21,120 --> 04:35:22,120
WOMEN'S HEALTH REPORTING 

7365
04:35:22,120 --> 04:35:22,960
INITIATIVE.

7366
04:35:22,960 --> 04:35:26,960
BEFORE TRANSITIONING TO THE 

7367
04:35:26,960 --> 04:35:29,280
EXTRAMURAL SETTING, DR. SHIEH 

7368
04:35:29,280 --> 04:35:34,080
WAS A RESEARCH ASSOCIATE AT THE 

7369
04:35:34,080 --> 04:35:35,920
NIH CLINICAL CENTER 

7370
04:35:35,920 --> 04:35:36,560
REHABILITATION MEDICINE 

7371
04:35:36,560 --> 04:35:39,520
DEPARTMENT AND HER RESEARCH IS 

7372
04:35:39,520 --> 04:35:42,880
THE DEMOGRAPHY OF AGING AND 

7373
04:35:42,880 --> 04:35:45,480
SOCIOLOGY OF WORK AND FAMILY AND

7374
04:35:45,480 --> 04:35:46,280
SOCIAL DETERMINATES OF HEALTH 

7375
04:35:46,280 --> 04:35:47,520
AND LIFE COURSE TRANSITION.

7376
04:35:47,520 --> 04:35:50,600
TRAINED IN QUANTITATIVE ARE 

7377
04:35:50,600 --> 04:35:52,200
RESEARCH METHODS, SHE'S 

7378
04:35:52,200 --> 04:35:53,720
PROFICIENT IN LONGITUDINAL 

7379
04:35:53,720 --> 04:35:55,200
MODELLING AND CLINICAL STUDY 

7380
04:35:55,200 --> 04:35:58,120
DESIGN AND METHODOLOGY AND 

7381
04:35:58,120 --> 04:35:59,120
FEDERAL INITIATIVE DATA ANALYSIS

7382
04:35:59,120 --> 04:36:00,560
AND COMPLEX DATA LINKING.

7383
04:36:00,560 --> 04:36:02,760
SHE RECEIVED HER Ph.D. IN 

7384
04:36:02,760 --> 04:36:09,640
SOCIOLOGY FROM THE UNIVERSITY OF

7385
04:36:09,640 --> 04:36:10,560
MARYLAND.

7386
04:36:10,560 --> 04:36:11,920
DR. CHANDLER AND CHING-YI.

7387
04:36:11,920 --> 04:36:14,400
I'D LIKE TO TURN TO THE SLIDE 

7388
04:36:14,400 --> 04:36:16,960
PRESENTATION AND HERE WE'D LIKE 

7389
04:36:16,960 --> 04:36:18,560
TO PROVIDE YOU WITH AN UPDATE ON

7390
04:36:18,560 --> 04:36:22,440
WHERE WE ARE WITH THE 2024, 2028

7391
04:36:22,440 --> 04:36:23,960
NIH STRATEGIC PLAN ON RESEARCH 

7392
04:36:23,960 --> 04:36:25,600
ON THE HEALTH OF WOMEN AND BY 

7393
04:36:25,600 --> 04:36:27,320
THE END OF THIS SHORT 

7394
04:36:27,320 --> 04:36:29,880
PRESENTATION, WE WILL SHARE WITH

7395
04:36:29,880 --> 04:36:32,040
YOU THE DRAFT OF THE MAIN TOPICS

7396
04:36:32,040 --> 04:36:36,600
THAT WE CAME UP WITH IN THE LAST

7397
04:36:36,600 --> 04:36:41,440
TWO MONTHS.

7398
04:36:41,440 --> 04:36:44,000
THE OVERARCHING GOAL OF THIS 

7399
04:36:44,000 --> 04:36:46,400
STRATEGIC PLAN IS TO PROVIDE A 

7400
04:36:46,400 --> 04:36:48,360
ROAD MAP TO GUIDE NIH-WIDE 

7401
04:36:48,360 --> 04:36:49,960
RESEARCH ON THE HEALTH OF WOMEN 

7402
04:36:49,960 --> 04:36:52,480
AND NOW WE ARE IN THE MIDST OF 

7403
04:36:52,480 --> 04:36:54,080
PLANNING FOR THE NEXT ONE WHICH 

7404
04:36:54,080 --> 04:36:56,600
WILL BE LAUNCHED IN JANUARY OF 

7405
04:36:56,600 --> 04:36:58,560
2024.

7406
04:36:58,560 --> 04:36:59,880
SO WHO DID WE INVOLVE IN THIS 

7407
04:36:59,880 --> 04:37:05,040
PROCESS?

7408
04:37:05,040 --> 04:37:08,600
AND WE'RE STILL IN THE MIDDLE OF

7409
04:37:08,600 --> 04:37:09,240
IT.

7410
04:37:09,240 --> 04:37:11,080
WE INVOLVED ALL OF OUR I.C.s, 

7411
04:37:11,080 --> 04:37:13,520
THE ICOs AND INSTITUTE CENTERS 

7412
04:37:13,520 --> 04:37:14,720
AND OFFICES WITHIN THE NIH 

7413
04:37:14,720 --> 04:37:17,520
THROUGH VARIOUS MECHANISMS.

7414
04:37:17,520 --> 04:37:20,680
AND WE INVOLVED MANY OF THE 

7415
04:37:20,680 --> 04:37:22,600
FEDERAL AGENCIES THAT HAVE 

7416
04:37:22,600 --> 04:37:24,360
INTERESTS AND FOCUS ON WOMEN'S 

7417
04:37:24,360 --> 04:37:24,960
HEALTH AND,000 HERE ON THIS 

7418
04:37:24,960 --> 04:37:28,760
SLIDE.

7419
04:37:28,760 --> 04:37:30,680
WE ALSO INVOLVED PUBLIC, PRIVATE

7420
04:37:30,680 --> 04:37:32,560
AND NON-PROFIT AND ADVOCACY 

7421
04:37:32,560 --> 04:37:34,800
GROUPS THROUGH THE RFI 

7422
04:37:34,800 --> 04:37:38,040
DR. CLAYTON MENTIONED WE HAD A 

7423
04:37:38,040 --> 04:37:39,360
REQUEST FOR INFORMATION OUT ON 

7424
04:37:39,360 --> 04:37:41,480
THE STREET SEVERAL MONTHS AND WE

7425
04:37:41,480 --> 04:37:44,720
RECEIVED INPUT MORE THAN 200 

7426
04:37:44,720 --> 04:37:46,120
INPUTS FROM THESE GROUPS WE WILL

7427
04:37:46,120 --> 04:37:47,240
SHARE WITH YOU.

7428
04:37:47,240 --> 04:37:51,520
SO WE REALLY TRIED TO CAST A 

7429
04:37:51,520 --> 04:37:54,160
WIDE NET OF WELCOMING SOLICITING

7430
04:37:54,160 --> 04:37:57,200
INPUT TO THIS SO WE CAN TRY TO 

7431
04:37:57,200 --> 04:37:57,800
MAKE IT AS COMPREHENSIVE AS 

7432
04:37:57,800 --> 04:38:03,880
POSSIBLE.

7433
04:38:03,880 --> 04:38:06,560
AS YOU RECALL, WE CREATED A 

7434
04:38:06,560 --> 04:38:09,600
WORKING GROUP WITH MEMBERS OF 

7435
04:38:09,600 --> 04:38:13,320
YOU OF THIS COMMITTEE.

7436
04:38:13,320 --> 04:38:15,880
THE ACRWH WORKING GROUP WAS 

7437
04:38:15,880 --> 04:38:19,120
CREATED AND IT IS CO-CHAIRED BY 

7438
04:38:19,120 --> 04:38:21,880
DR. ALLISON McGREGOR WHO IS HERE

7439
04:38:21,880 --> 04:38:22,880
WITH US TODAY.

7440
04:38:22,880 --> 04:38:24,840
SHE'S THE CO-CHAIR OF THIS 

7441
04:38:24,840 --> 04:38:25,640
WORKING GROUP.

7442
04:38:25,640 --> 04:38:27,680
AND THE CHALLENGE OF THE WORKING

7443
04:38:27,680 --> 04:38:29,360
GROUP IS TO ADDRESS THE CURRENT 

7444
04:38:29,360 --> 04:38:32,080
STATE OF SCIENCE ON THE HEALTH 

7445
04:38:32,080 --> 04:38:33,600
OF WOMEN RESEARCH GAPS AND 

7446
04:38:33,600 --> 04:38:37,600
IDENTIFY GOALS AND OBJECTIVES 

7447
04:38:37,600 --> 04:38:39,480
ORWH NEEDS TO PRIORITIZE FROM 

7448
04:38:39,480 --> 04:38:40,880
2024 TO 2028.

7449
04:38:40,880 --> 04:38:44,880
WE HAVE MET AND HAD A KICKOFF 

7450
04:38:44,880 --> 04:38:45,880
MEETING THAT INVOLVED THE 

7451
04:38:45,880 --> 04:38:48,680
MEMBERS OF THE WORKING GROUP AND

7452
04:38:48,680 --> 04:38:51,720
THIS WORKING GROUP INCLUDED 

7453
04:38:51,720 --> 04:38:53,640
MEMBERS FROM NIH AND THE FEDERAL

7454
04:38:53,640 --> 04:38:55,160
AGENCY I MENTIONED EARLIER.

7455
04:38:55,160 --> 04:38:57,320
DURING THE MEETING WE ALSO 

7456
04:38:57,320 --> 04:39:00,000
REVIEWED THE IMPLEMENTATION OF 

7457
04:39:00,000 --> 04:39:03,440
THE 2019 TO 2023 THE CURRENT 

7458
04:39:03,440 --> 04:39:05,400
STRATEGIC PLAN ON THE RESEARCH 

7459
04:39:05,400 --> 04:39:06,240
OF HEALTH OF WOMEN.

7460
04:39:06,240 --> 04:39:08,200
WHAT WE WILL DO TODAY IS REVIEW 

7461
04:39:08,200 --> 04:39:10,280
WHAT WE HAVE DONE SINCE THE 

7462
04:39:10,280 --> 04:39:12,080
KICKOFF MEETING WHICH WE HAD 

7463
04:39:12,080 --> 04:39:12,440
UNTIL NOW.

7464
04:39:12,440 --> 04:39:15,320
SO I WOULD LIKE TO TURN IT AND 

7465
04:39:15,320 --> 04:39:17,760
WE SPLIT THE IT UP IN A WAY I 

7466
04:39:17,760 --> 04:39:19,200
GAVE THE BACK, I'D LIKE TO TURN 

7467
04:39:19,200 --> 04:39:20,280
IT TO MY COLLEAGUE, 

7468
04:39:20,280 --> 04:39:24,280
DR. CHANDLER, TO TALK ABOUT THE 

7469
04:39:24,280 --> 04:39:27,520
PROCESS AND THEN DR. SHIEH WILL 

7470
04:39:27,520 --> 04:39:29,920
SHOW THE RESULTS.

7471
04:39:29,920 --> 04:39:32,160
WITH THAT I'LL TURN IT TO 

7472
04:39:32,160 --> 04:39:32,840
DR. CHANDLER.

7473
04:39:32,840 --> 04:39:33,200
KELLY.

7474
04:39:33,200 --> 04:39:38,400
>>THANK YOU, DR. NOURSI.

7475
04:39:38,400 --> 04:39:39,360
ORWH ENGINEERED A PROCESS MODEL 

7476
04:39:39,360 --> 04:39:42,160
FOR KEY STEPS FOR THE NEXT 

7477
04:39:42,160 --> 04:39:42,880
NIH-WIDE STRATEGIC PLAN ON 

7478
04:39:42,880 --> 04:39:44,800
RESEARCH ON THE HEALTH OF WOMEN.

7479
04:39:44,800 --> 04:39:46,200
THIS PROCESS BEGIN WITH 

7480
04:39:46,200 --> 04:39:47,920
COLLECTING AND ANALYZING DATA 

7481
04:39:47,920 --> 04:39:51,920
FROM A VARIETY OF ACTIVITIES 

7482
04:39:51,920 --> 04:39:54,600
ALONG SIDE ACRWH.

7483
04:39:54,600 --> 04:39:57,480
WE THEN ESTABLISHED A STRATEGIC 

7484
04:39:57,480 --> 04:40:01,800
PLAN WORKING GROUP LED BY 

7485
04:40:01,800 --> 04:40:06,040
DOCTORS McGREGOR AND NOURSI AND 

7486
04:40:06,040 --> 04:40:09,000
REPRESENTATIVES AND MEMBERS AND 

7487
04:40:09,000 --> 04:40:09,520
FEDERAL PARTNERS.

7488
04:40:09,520 --> 04:40:10,760
INITIAL FINDINGS FROM THE DATA 

7489
04:40:10,760 --> 04:40:12,320
ANALYSIS WERE PRESENTED TO THE 

7490
04:40:12,320 --> 04:40:13,360
STRATEGIC PLAN WORKING GROUP AND

7491
04:40:13,360 --> 04:40:16,200
THE KICKOFF MEETING WAS HELD 

7492
04:40:16,200 --> 04:40:17,720
JUNE 30 AND FEEDBACK WAS 

7493
04:40:17,720 --> 04:40:19,040
OBTAINED FROM THE STRATEGIC PLAN

7494
04:40:19,040 --> 04:40:20,440
WORKING GROUP DURING THE MEETING

7495
04:40:20,440 --> 04:40:21,520
AS WELL AS THROUGH OUTREACH 

7496
04:40:21,520 --> 04:40:24,960
EFFORTS AFTER THE MEETING.

7497
04:40:24,960 --> 04:40:28,600
TODAY WE'LL BE PRESENTING THE 

7498
04:40:28,600 --> 04:40:31,280
PROPOSED STRATEGIC PLAN CONTENT 

7499
04:40:31,280 --> 04:40:32,520
AREAS DEVELOPED DURING THE 

7500
04:40:32,520 --> 04:40:34,720
KICKOFF MEETING AS WELL AS AN 

7501
04:40:34,720 --> 04:40:37,320
RFI, I.C. DIRECTORS MEETINGS, 

7502
04:40:37,320 --> 04:40:38,320
INTERNAL ORWH MEETINGS AND 

7503
04:40:38,320 --> 04:40:45,680
MEETING HERE WITH YOU ALL TODAY.

7504
04:40:45,680 --> 04:40:48,600
ONCE THE CONTENT IS APPROVED 

7505
04:40:48,600 --> 04:40:49,720
WE'LL RECUSE THINK TANK GROUPS 

7506
04:40:49,720 --> 04:40:50,720
FROM THE COORDINATING COMMITTEE 

7507
04:40:50,720 --> 04:40:52,320
AND RESEARCH ON WOMEN'S HEALTH 

7508
04:40:52,320 --> 04:40:56,640
AND THE ICO SUBJECT MATTER 

7509
04:40:56,640 --> 04:40:58,040
EXPERTS AND THE EVALUATION 

7510
04:40:58,040 --> 04:40:59,680
REPRESENTATIVE AT NIH AND 

7511
04:40:59,680 --> 04:41:01,560
WORKING GROUP MEMBERS AS WELL AS

7512
04:41:01,560 --> 04:41:05,760
FEDERAL PARTNERS.

7513
04:41:05,760 --> 04:41:09,280
THEY'LL WORK TOGETHER TO DEVELOP

7514
04:41:09,280 --> 04:41:10,040
THE STRATEGIC GOALS AND 

7515
04:41:10,040 --> 04:41:12,800
STRATEGIC OBJECTIVES AND METRICS

7516
04:41:12,800 --> 04:41:14,080
FOR EACH OF THE GOALS.

7517
04:41:14,080 --> 04:41:15,680
ORWH WILL THEN DRAFT THE 

7518
04:41:15,680 --> 04:41:17,200
STRATEGIC PLAN WHICH WILL BE 

7519
04:41:17,200 --> 04:41:19,840
PUBLISHED IN JANUARY OF 2024 

7520
04:41:19,840 --> 04:41:21,920
FOLLOWED BY AN IMPLEMENTATION 

7521
04:41:21,920 --> 04:41:23,000
AND EVALUATION GUIDE WHICH WILL 

7522
04:41:23,000 --> 04:41:24,520
THEN BE PUBLISHED SIX MONTHS 

7523
04:41:24,520 --> 04:41:24,720
LATER.

7524
04:41:24,720 --> 04:41:27,480
SO TODAY, WE ARE HERE IN THE 

7525
04:41:27,480 --> 04:41:30,800
PROCESS OF DEVELOPING THE 

7526
04:41:30,800 --> 04:41:31,160
STRATEGIC PLAN.

7527
04:41:31,160 --> 04:41:33,840
WE'RE EXCITED TO SHARE THE DRAFT

7528
04:41:33,840 --> 04:41:34,320
CONTENT AREAS FOR YOUR 

7529
04:41:34,320 --> 04:41:42,680
CONSIDERATION.

7530
04:41:42,680 --> 04:41:45,640
THEY WERE DEVELOPED WITH ORWH 

7531
04:41:45,640 --> 04:41:46,560
GENERATING INTENTIONAL SYNERGY 

7532
04:41:46,560 --> 04:41:47,840
FOR THE ACTIVITIES TO PROVIDE 

7533
04:41:47,840 --> 04:41:50,960
DATA THAT COULD BE ANALYZED 

7534
04:41:50,960 --> 04:41:51,640
QUALITATIVELY AND LEVERAGED TO 

7535
04:41:51,640 --> 04:41:53,560
BUILD THE CONTENT AREAS.

7536
04:41:53,560 --> 04:41:56,720
WE DO VALUE YOU'RE TIME AND 

7537
04:41:56,720 --> 04:41:58,600
INPUT AND MADE SIGNIFICANT 

7538
04:41:58,600 --> 04:41:59,640
ANALYTICAL EFFORTS IN A SHORT 

7539
04:41:59,640 --> 04:42:00,600
PERIOD OF TIME TO PRESENT THIS 

7540
04:42:00,600 --> 04:42:01,920
DATA TO YOU TODAY.

7541
04:42:01,920 --> 04:42:04,440
SO JUST TO PUT IT IN 

7542
04:42:04,440 --> 04:42:05,680
PERSPECTIVE, WITH ALMOST HALF 

7543
04:42:05,680 --> 04:42:08,360
THE RFI RESPONSES SUBMITTED IN 

7544
04:42:08,360 --> 04:42:11,240
THE TENTH AND FINAL WEEK ON THE 

7545
04:42:11,240 --> 04:42:12,520
STREET, THE LION'S SHARE OF THE 

7546
04:42:12,520 --> 04:42:15,520
ANALYZE HAD TO BE CONDUCTED IN A

7547
04:42:15,520 --> 04:42:18,160
SHORT PERIOD OF TIME.

7548
04:42:18,160 --> 04:42:20,160
LIKEWISE ALMOST THREE-QUARTERS 

7549
04:42:20,160 --> 04:42:21,280
OF THE DIRECTORS MEETING 

7550
04:42:21,280 --> 04:42:22,080
OCCURRED THROUGH AUGUST AND 

7551
04:42:22,080 --> 04:42:22,360
SEPTEMBER.

7552
04:42:22,360 --> 04:42:25,960
WE WORKED HARD TO ENSURE WE HAVE

7553
04:42:25,960 --> 04:42:29,360
THE DATA AND CAN MAKE AN 

7554
04:42:29,360 --> 04:42:29,880
EVIDENCE-BASED DECISION 

7555
04:42:29,880 --> 04:42:31,360
REGARDING THE CONTENT AREAS.

7556
04:42:31,360 --> 04:42:32,600
THE CONTENT ANALYSIS DATA 

7557
04:42:32,600 --> 04:42:34,360
COLLECTION WAS CONDUCTED ACROSS 

7558
04:42:34,360 --> 04:42:35,720
FOUR DIFFERENT ACTIVITIES, WHICH

7559
04:42:35,720 --> 04:42:38,120
I'LL WALK YOU THROUGH NOW.

7560
04:42:38,120 --> 04:42:40,200
THE FIRST WAS THE STRATEGIC PLAN

7561
04:42:40,200 --> 04:42:42,120
WORKING GROUP KICKOFF MEETING 

7562
04:42:42,120 --> 04:42:43,080
HELD IN JUNE.

7563
04:42:43,080 --> 04:42:46,080
SO ANALYSES ACROSS MULTIPLE DATA

7564
04:42:46,080 --> 04:42:49,040
SOURCES WERE PERFORMED BY ACWH 

7565
04:42:49,040 --> 04:42:50,280
MEMBERS AND STAFF PRIOR TO THE 

7566
04:42:50,280 --> 04:42:51,520
MEETING AND SUBSEQUENTLY 

7567
04:42:51,520 --> 04:42:52,600
PRESENTED TO THE GROUP FOLLOWED 

7568
04:42:52,600 --> 04:42:55,600
BY GUIDED DISCUSSION.

7569
04:42:55,600 --> 04:42:58,480
TO REALLY MAXIMIZE PARTICIPANT 

7570
04:42:58,480 --> 04:42:59,600
INPUT WORKING GROUP NUMBERS WERE

7571
04:42:59,600 --> 04:43:01,160
PROVIDED TO GUIDE THE DISCUSSION

7572
04:43:01,160 --> 04:43:02,200
QUESTIONS IN ADVANCE OF THE 

7573
04:43:02,200 --> 04:43:02,600
MEETING.

7574
04:43:02,600 --> 04:43:05,200
THIS RESULTED IN 29 INPUTS WHICH

7575
04:43:05,200 --> 04:43:06,760
WERE RECEIVED VIA COMMUNICATION 

7576
04:43:06,760 --> 04:43:08,400
DURING THE MEETING ITSELF AND 

7577
04:43:08,400 --> 04:43:12,280
THEN AFTER THE KICKOFF MEETING.

7578
04:43:12,280 --> 04:43:14,760
THE NEXT SOURCE I WANT TO TALK 

7579
04:43:14,760 --> 04:43:17,160
ABOUT IS THE ICO DIRECTORS 

7580
04:43:17,160 --> 04:43:17,440
MEETINGS.

7581
04:43:17,440 --> 04:43:21,520
THEY'RE MANDATED BY THE 21st 

7582
04:43:21,520 --> 04:43:24,600
CENTURY CURES ACT WHEREBY THEY 

7583
04:43:24,600 --> 04:43:26,360
MUST MEET ANNUALLY TO ENSURE THE

7584
04:43:26,360 --> 04:43:29,560
HEALTH OF WOMEN IS CAPTURED IN 

7585
04:43:29,560 --> 04:43:31,320
THEIR RESPECTIVE STRATEGIC 

7586
04:43:31,320 --> 04:43:32,640
PLANS.

7587
04:43:32,640 --> 04:43:33,960
AGAIN, ORWH WAS STRATEGIC IN 

7588
04:43:33,960 --> 04:43:36,360
LEVERAGING THESE MEETINGS TO 

7589
04:43:36,360 --> 04:43:39,320
OBTAIN INPUT ON NEXT NIH-WIDE 

7590
04:43:39,320 --> 04:43:40,200
STRATEGIC PLAN ON THE RESEARCH 

7591
04:43:40,200 --> 04:43:43,240
ON THE HEALTH OF WOMEN.

7592
04:43:43,240 --> 04:43:44,640
DIRECTORS WERE PROVIDED GUIDED 

7593
04:43:44,640 --> 04:43:45,800
QUESTIONS AND ONE ASKED THE 

7594
04:43:45,800 --> 04:43:47,800
DIRECTORS TO SHARE WHAT THEY HAD

7595
04:43:47,800 --> 04:43:49,880
IDENTIFIED AS THE MOST CRITICAL 

7596
04:43:49,880 --> 04:43:51,800
WOMEN'S HEALTH TOPICS WITHIN THE

7597
04:43:51,800 --> 04:43:52,480
CONTEXT OF THEIR ORGANIZATION'S 

7598
04:43:52,480 --> 04:43:54,920
MISSIONS.

7599
04:43:54,920 --> 04:43:57,240
ALL BUT FIVE ICO DIRECTORS 

7600
04:43:57,240 --> 04:43:58,600
PARTICIPATED WITH THE REMAINING 

7601
04:43:58,600 --> 04:44:00,600
DIRECTORS SCHEDULED FOR EARLY 

7602
04:44:00,600 --> 04:44:02,040
NOVEMBER.

7603
04:44:02,040 --> 04:44:03,920
IN TOTAL THE MEETINGS RESULTED 

7604
04:44:03,920 --> 04:44:07,480
IN 32 INPUTS FROM DIRECTORS AND 

7605
04:44:07,480 --> 04:44:08,600
SENIOR LEVEL STAFF WHO 

7606
04:44:08,600 --> 04:44:11,280
PARTICIPATED IN THE MEETINGS.

7607
04:44:11,280 --> 04:44:17,200
SO IN CONJUNCTION WITH YOU ALL, 

7608
04:44:17,200 --> 04:44:19,000
ORWH PUBLISHED A REQUEST FOR 

7609
04:44:19,000 --> 04:44:20,520
INFORMATION TO SOLICIT COMMENTS 

7610
04:44:20,520 --> 04:44:23,280
FROM SCIENTISTS, ADVOCACY AND 

7611
04:44:23,280 --> 04:44:25,080
COMMUNITIES AND THE GENERAL 

7612
04:44:25,080 --> 04:44:26,760
PUBLIC.

7613
04:44:26,760 --> 04:44:28,720
RFI CLOSED SEPTEMBER 29 WITH 

7614
04:44:28,720 --> 04:44:34,520
ANALYZATION OF 20 COMMENTS AND 

7615
04:44:34,520 --> 04:44:36,320
ENSURE THE PERSPECTIVES WERE 

7616
04:44:36,320 --> 04:44:38,760
AVAILABLE TO YOU ALL AND THEY 

7617
04:44:38,760 --> 04:44:40,000
GATHERED TO LOOK AT INPUTS 

7618
04:44:40,000 --> 04:44:41,000
CONTRIBUTING TO THE CONTENT 

7619
04:44:41,000 --> 04:44:42,880
AREAS YOU'LL HEAR ABOUT NOW FROM

7620
04:44:42,880 --> 04:44:49,200
MY COLLEAGUE, DR. SHIEH.

7621
04:44:49,200 --> 04:44:59,640
>>THANK YOU DR. CHANDLER.

7622
04:45:00,000 --> 04:45:03,520
THEY ASKED AMONG SO MANY TOPICS 

7623
04:45:03,520 --> 04:45:05,440
RELEVANT TO THE HEALTH OF WOMEN 

7624
04:45:05,440 --> 04:45:07,600
WHAT ARE THE ESSENTIAL TOPICS 

7625
04:45:07,600 --> 04:45:09,600
FOR NIH TO FOCUS ON IN THE NEXT 

7626
04:45:09,600 --> 04:45:11,160
ROUND OF THE STRATEGIC PLAN.

7627
04:45:11,160 --> 04:45:13,880
WE CONDUCTED QUALITATIVE DATA 

7628
04:45:13,880 --> 04:45:18,000
ANALYSIS TO SUMMARIZE THIS INPUT

7629
04:45:18,000 --> 04:45:20,960
AND PROVIDE CODING ASSESSMENT TO

7630
04:45:20,960 --> 04:45:24,480
RECONCILE THE INCONSISTENCIES.

7631
04:45:24,480 --> 04:45:26,680
WE GENERATED DRAFT CONTENT AREAS

7632
04:45:26,680 --> 04:45:27,520
AND WELCOME YOUR FURTHER 

7633
04:45:27,520 --> 04:45:31,400
COMMENTS TODAY.

7634
04:45:31,400 --> 04:45:32,920
BECAUSE SOME RECOMMENDATIONS 

7635
04:45:32,920 --> 04:45:36,040
INVOLVE MULTIPLE CONCEPT, THE 

7636
04:45:36,040 --> 04:45:39,200
DRAFT AREAS MAY NOT BE MUTUALLY 

7637
04:45:39,200 --> 04:45:41,720
EXCLUSIVE.

7638
04:45:41,720 --> 04:45:43,120
MOREOVER, SINCE THE AREAS GO TO 

7639
04:45:43,120 --> 04:45:44,280
INFORM THE DEVELOPMENT OF THE 

7640
04:45:44,280 --> 04:45:48,080
NIH STRATEGIC PLAN, WE SHOULD 

7641
04:45:48,080 --> 04:45:50,520
IDENTIFY BROADER RESEARCH TO 

7642
04:45:50,520 --> 04:45:52,600
GUIDE NIH-WIDE SCIENTIFIC 

7643
04:45:52,600 --> 04:45:55,040
EFFORTS INSTEAD OF TARGETING 

7644
04:45:55,040 --> 04:45:56,560
SPECIFIC DISEASES OR HEALTH 

7645
04:45:56,560 --> 04:45:56,920
CONDITIONS.

7646
04:45:56,920 --> 04:45:58,520
ALIGN WITH THEIR MISSIONS, 

7647
04:45:58,520 --> 04:46:01,120
INDIVIDUAL ICOs HAVE THE 

7648
04:46:01,120 --> 04:46:02,560
EXPERTISE TO DECIDE WHAT TYPE OF

7649
04:46:02,560 --> 04:46:04,000
HEALTH CONDITIONS THEY WANT TO 

7650
04:46:04,000 --> 04:46:05,680
OCCASION ON AND OPERATIONALIZE 

7651
04:46:05,680 --> 04:46:11,040
THEIR STUDY DESIGNS.

7652
04:46:11,040 --> 04:46:13,080
NOW, WE WILL PRESENT THE TOP 

7653
04:46:13,080 --> 04:46:14,280
FIVE DRAFT CONTENT AREAS.

7654
04:46:14,280 --> 04:46:19,360
THE FIRST DRAFT CONTENT AREA IS 

7655
04:46:19,360 --> 04:46:21,160
CONSIDERED HOW THEIR 

7656
04:46:21,160 --> 04:46:23,000
INTERSECTION OF ASSOCIATION AND 

7657
04:46:23,000 --> 04:46:24,000
BIOLOGICAL FACTORS AFFECT THE 

7658
04:46:24,000 --> 04:46:25,400
HEALTH OF WOMEN.

7659
04:46:25,400 --> 04:46:27,520
THIS BRINGS INTERSECTION 

7660
04:46:27,520 --> 04:46:29,680
TOGETHER AND SIGNIFIES THAT AND 

7661
04:46:29,680 --> 04:46:31,840
TO CHARACTERIZE THE HEALTH OF 

7662
04:46:31,840 --> 04:46:34,280
WOMEN MORE HOLISTICALLY.

7663
04:46:34,280 --> 04:46:35,920
AND THE DRAFT CONTENT AREA WE 

7664
04:46:35,920 --> 04:46:38,680
WILL STUDY THE HEALTH OF WOMEN 

7665
04:46:38,680 --> 04:46:40,520
IN CONTEXT AND EXAMINE HEALTH 

7666
04:46:40,520 --> 04:46:42,600
CONDITIONS ACROSS THE LIFE 

7667
04:46:42,600 --> 04:46:45,040
COURSE AS A CONTINUUM.

7668
04:46:45,040 --> 04:46:47,720
WE ADDRESSED MINORITY HEALTH 

7669
04:46:47,720 --> 04:46:49,840
HEALTH DISPARITY AND HEALTH 

7670
04:46:49,840 --> 04:46:50,360
EQUITY.

7671
04:46:50,360 --> 04:46:52,480
ASSESS MULTI-DIMENSIONAL 

7672
04:46:52,480 --> 04:46:54,320
INFERENCES SUCH AS THE AFFECT OF

7673
04:46:54,320 --> 04:46:56,600
GENDER NORMS, STRUCTURAL RACISM 

7674
04:46:56,600 --> 04:46:59,000
AND POLICY CHANGE.

7675
04:46:59,000 --> 04:47:02,200
AND WE LOOK AT THE INTERSECTION 

7676
04:47:02,200 --> 04:47:04,120
OF SOCIAL DEMOGRAPHIC, 

7677
04:47:04,120 --> 04:47:08,640
BEHAVIORAL AND ENVIRONMENTAL AND

7678
04:47:08,640 --> 04:47:09,080
BIOLOGICAL FACTORS.

7679
04:47:09,080 --> 04:47:11,360
AND THE DRAFT CONTENT AREAS SUCH

7680
04:47:11,360 --> 04:47:15,520
AS NIH-SUPPORTED DEVELOPMENT OF 

7681
04:47:15,520 --> 04:47:20,560
DATA SCIENCE IN RESEARCH METHODS

7682
04:47:20,560 --> 04:47:27,560
AND MEASUREMENTS AND WE LOOK AT 

7683
04:47:27,560 --> 04:47:30,600
BIG DATA ANALYSIS AND THE 

7684
04:47:30,600 --> 04:47:31,640
SOPHISTICATED MODELLING METHODS 

7685
04:47:31,640 --> 04:47:32,680
AS WELL AS ARTIFICIAL 

7686
04:47:32,680 --> 04:47:33,280
INTELLIGENCE AND THE MACHINE 

7687
04:47:33,280 --> 04:47:38,080
LEARNING RESEARCH.

7688
04:47:38,080 --> 04:47:45,120
WE USE REPEATED MEASUREMENT AND 

7689
04:47:45,120 --> 04:47:46,120
LONGITUDINAL DATA TO ASSESS 

7690
04:47:46,120 --> 04:47:48,440
HEALTH OVER TIME AND FACILITATE 

7691
04:47:48,440 --> 04:47:50,800
SCREENING AND DIAGNOSIS AND 

7692
04:47:50,800 --> 04:47:51,600
TREATMENT.

7693
04:47:51,600 --> 04:47:54,240
ALSO, WE WILL URGE SCIENTIST TO 

7694
04:47:54,240 --> 04:47:55,560
RECRUIT ENOUGH WOMEN 

7695
04:47:55,560 --> 04:47:57,480
PARTICIPANTS TO SUPPORT CLINICAL

7696
04:47:57,480 --> 04:47:58,440
STUDIES SO THAT THE RESEARCH 

7697
04:47:58,440 --> 04:48:00,680
FINDINGS WILL HAVE A SOLID 

7698
04:48:00,680 --> 04:48:05,320
EVIDENCE BASE.

7699
04:48:05,320 --> 04:48:08,320
OUR THIRD DRAFT CONTENT AREA IS 

7700
04:48:08,320 --> 04:48:09,560
SUPPORT BIO MEDICAL WORKFORCE 

7701
04:48:09,560 --> 04:48:12,360
TRAINING AND PROMOTE WOMEN 

7702
04:48:12,360 --> 04:48:13,680
SCIENTIST CAREER DEVELOPMENT TO 

7703
04:48:13,680 --> 04:48:15,280
ADVANCE THE HEALTH OF WOMEN.

7704
04:48:15,280 --> 04:48:17,280
WE WILL CONTINUE MAKING EFFORTS 

7705
04:48:17,280 --> 04:48:21,520
TO DEVELOP A WELL-TRAINED AND 

7706
04:48:21,520 --> 04:48:23,600
DIVERSE SCIENTIFIC WORKFORCE, 

7707
04:48:23,600 --> 04:48:24,280
INCREASE THE REPRESENTATION OF 

7708
04:48:24,280 --> 04:48:27,360
WOMEN SCIENTIST IN THE 

7709
04:48:27,360 --> 04:48:29,760
WORKFORCE, ADDRESS ISSUES IN 

7710
04:48:29,760 --> 04:48:32,600
RELATION TO WOMEN SCIENTIST AND 

7711
04:48:32,600 --> 04:48:35,440
RETENTION AND PROMOTION AND 

7712
04:48:35,440 --> 04:48:36,600
SUGGESTION ACTION TO ENHANCE 

7713
04:48:36,600 --> 04:48:40,640
FUNDING EQUITY.

7714
04:48:40,640 --> 04:48:42,560
THE FOURTH CONTENT AREA IS 

7715
04:48:42,560 --> 04:48:43,640
ADVANCE BASIC SCIENCE AND 

7716
04:48:43,640 --> 04:48:45,360
TRANSLATIONAL RESEARCH TO 

7717
04:48:45,360 --> 04:48:47,280
IMPROVE THE HEALTH OF WOMEN.

7718
04:48:47,280 --> 04:48:52,280
WE WILL CONTINUE TO PROMOTE 

7719
04:48:52,280 --> 04:48:52,720
EFFORTS AND EVALUATE 

7720
04:48:52,720 --> 04:49:00,720
IMPLEMENTATION OUTCOMES.

7721
04:49:00,720 --> 04:49:03,120
EXAMINE THE UNDERLYING 

7722
04:49:03,120 --> 04:49:04,200
MECHANISMS TO LOOK AT DIAGNOSIS 

7723
04:49:04,200 --> 04:49:05,000
AND TREATMENT.

7724
04:49:05,000 --> 04:49:08,600
LIKEWISE, WE NEED TO IMPROVE 

7725
04:49:08,600 --> 04:49:10,200
TRANSLATIONAL RESEARCH OUTCOMES 

7726
04:49:10,200 --> 04:49:12,280
IN PARTICULAR DO OUR BEST TO 

7727
04:49:12,280 --> 04:49:15,880
ENSURE PRECLINICAL STUDY AND THE

7728
04:49:15,880 --> 04:49:16,640
ANIMAL MODEL INTO HUMAN SUBJECT 

7729
04:49:16,640 --> 04:49:19,880
RESEARCH.

7730
04:49:19,880 --> 04:49:22,680
THE FIFTH DRAFT AREA IS 

7731
04:49:22,680 --> 04:49:24,560
ENCOURAGE COMMUNITY ENGAGEMENT 

7732
04:49:24,560 --> 04:49:25,560
AND PROMOTE IMPLEMENTATION 

7733
04:49:25,560 --> 04:49:29,120
SCIENCE FOR THE HEALTH OF WOMEN 

7734
04:49:29,120 --> 04:49:33,280
WHICH INCLUDES APPLIED STUDY 

7735
04:49:33,280 --> 04:49:36,160
RESULT TO REAL WORK AND LOOK AT 

7736
04:49:36,160 --> 04:49:37,760
CULTURALLY COMPETENT 

7737
04:49:37,760 --> 04:49:38,800
INTERVENTIONS, COLLABORATE WITH 

7738
04:49:38,800 --> 04:49:40,880
COMMUNITIES AND ORGANIZATIONS TO

7739
04:49:40,880 --> 04:49:44,000
IMPROVE HEALTH CARE DELIVERY 

7740
04:49:44,000 --> 04:49:44,280
OUTCOMES.

7741
04:49:44,280 --> 04:49:49,840
WE DEVELOPED GUIDANCE AND 

7742
04:49:49,840 --> 04:49:51,200
PROVIDE THE REQUIRED EDUCATION 

7743
04:49:51,200 --> 04:49:53,000
AS WELL AS PROVIDE COMMUNITY 

7744
04:49:53,000 --> 04:49:58,680
ENGAGEMENT IS SUSTAINABLE.

7745
04:49:58,680 --> 04:50:00,920
WE ALSO IDENTIFIED SEVERAL 

7746
04:50:00,920 --> 04:50:02,600
TOPICS THAT COHORT SCIENTIFIC 

7747
04:50:02,600 --> 04:50:03,160
INVESTIGATIONS.

7748
04:50:03,160 --> 04:50:06,040
SOME OF THEM ARE MORE 

7749
04:50:06,040 --> 04:50:08,000
CROSS-CUTTING FOR INSTANCE, 

7750
04:50:08,000 --> 04:50:10,000
STUDY COMORBIDITY AND 

7751
04:50:10,000 --> 04:50:10,640
MULTI-MORBIDITY.

7752
04:50:10,640 --> 04:50:12,920
OTHERS ARE MORE SPECIFIC SUCH AS

7753
04:50:12,920 --> 04:50:15,000
HEALTH CONDITIONS AFFECTING 

7754
04:50:15,000 --> 04:50:19,000
WOMEN AND GIRLS INCLUDING BUT 

7755
04:50:19,000 --> 04:50:22,840
NOT LIMITED TO AUTOIMMUNE 

7756
04:50:22,840 --> 04:50:24,560
DISEASES AND MENOPAUSE AND 

7757
04:50:24,560 --> 04:50:25,840
RESEARCH IS COMPLEX AND 

7758
04:50:25,840 --> 04:50:28,200
IMPOSSIBLE TO INCLUDE EVERYTHING

7759
04:50:28,200 --> 04:50:30,520
ON OUR LIST HOWEVER, THE KEY 

7760
04:50:30,520 --> 04:50:33,480
POINTS EMBEDDED IN THE FIVE 

7761
04:50:33,480 --> 04:50:35,480
RECOMMENDED DRAFT AREAS CAN 

7762
04:50:35,480 --> 04:50:36,000
GUIDE VARIOUS RESEARCH.

7763
04:50:36,000 --> 04:50:38,640
FOR EXAMPLE, SCIENTISTS CAN 

7764
04:50:38,640 --> 04:50:42,560
SOMEONE WOMEN'S MENTAL HEALTH 

7765
04:50:42,560 --> 04:50:46,000
ISSUES FROM A CAREER DEVELOPMENT

7766
04:50:46,000 --> 04:50:48,480
AND WORK PERSPECTIVE USING BASIC

7767
04:50:48,480 --> 04:50:50,720
SCIENCE OR CLINICAL RESEARCH 

7768
04:50:50,720 --> 04:50:52,600
DESIGN OR COMBINATION OF THESE.

7769
04:50:52,600 --> 04:50:54,360
WE BELIEVE ALL THESE EFFORTS ARE

7770
04:50:54,360 --> 04:50:56,640
IMPORTANT TO HELP US UNDERSTAND 

7771
04:50:56,640 --> 04:50:57,840
THE HEALTH OF WOMEN.

7772
04:50:57,840 --> 04:51:00,280
NEXT LET ME TURN IT TO 

7773
04:51:00,280 --> 04:51:01,960
DR. NOURSI.

7774
04:51:01,960 --> 04:51:02,560
THANK YOU.

7775
04:51:02,560 --> 04:51:04,360
>>THANK YOU.

7776
04:51:04,360 --> 04:51:08,360
THANK YOU, DOCTORS CHANDLER AND 

7777
04:51:08,360 --> 04:51:08,600
SHIEH.

7778
04:51:08,600 --> 04:51:12,520
IN ADDITION TO WHAT HAS BEEN 

7779
04:51:12,520 --> 04:51:14,200
PRESENTED SO FAR THERE WERE OVER

7780
04:51:14,200 --> 04:51:15,280
ARCHING PRINCIPLES THAT CAME 

7781
04:51:15,280 --> 04:51:16,600
THROUGHOUT THE DATA WE GATHERED 

7782
04:51:16,600 --> 04:51:18,560
AND THE INPUT WE RECEIVED AND 

7783
04:51:18,560 --> 04:51:23,360
THEY ARE THE THREE THAT ARE 

7784
04:51:23,360 --> 04:51:25,360
LISTED HERE TO ENCOURAGE 

7785
04:51:25,360 --> 04:51:28,640
CROSS-NIH ICO PARTNERSHIP AND 

7786
04:51:28,640 --> 04:51:30,480
COLLABORATION BETWEEN THE NIH 

7787
04:51:30,480 --> 04:51:33,480
COMMUNITY AND PRIORITIZE 

7788
04:51:33,480 --> 04:51:35,440
INTERDISCIPLINARY RESEARCH AND 

7789
04:51:35,440 --> 04:51:37,320
CONSIDER THE GOALS OF NIH 

7790
04:51:37,320 --> 04:51:42,280
DIVERSITY, EQUITY, INCLUSION AND

7791
04:51:42,280 --> 04:51:42,680
ACCESSIBILITY.

7792
04:51:42,680 --> 04:51:44,600
THOSE WERE OVER ARCHING 

7793
04:51:44,600 --> 04:51:46,160
PRINCIPLES THAT CAME TO US AND 

7794
04:51:46,160 --> 04:51:47,520
WE'LL KEEP THEM IN MIND AS THE 

7795
04:51:47,520 --> 04:51:55,080
PLAN IS BEING DEVELOPED.

7796
04:51:55,080 --> 04:51:56,600
THE NEXT IS TO TAKE QUESTIONS 

7797
04:51:56,600 --> 04:51:58,440
FROM EVERYONE.

7798
04:51:58,440 --> 04:52:02,240
I'D LIKE TO ASK DR. SHIEH AND 

7799
04:52:02,240 --> 04:52:03,640
CHANDLER TO COME BACK ON CAMERA 

7800
04:52:03,640 --> 04:52:05,240
AND SEE IF WE HAVE QUESTIONS 

7801
04:52:05,240 --> 04:52:08,640
FROM THE MEMBERS BEFORE WE MOVE 

7802
04:52:08,640 --> 04:52:11,000
ON TO THE VOTE.

7803
04:52:11,000 --> 04:52:15,840
DR. RIGENSTEINER, DID YOU HAVE A

7804
04:52:15,840 --> 04:52:16,120
QUESTION?

7805
04:52:16,120 --> 04:52:16,320
>>YES.

7806
04:52:16,320 --> 04:52:18,280
TWO THINGS.

7807
04:52:18,280 --> 04:52:19,560
FIRST OF ALL THIS WAS REALLY 

7808
04:52:19,560 --> 04:52:20,600
INTERESTED AND WELL PRESENTED 

7809
04:52:20,600 --> 04:52:23,080
BUT I HAD A COUPLE THINGS I 

7810
04:52:23,080 --> 04:52:25,360
DIDN'T HEAR SAID I THINK NEED TO

7811
04:52:25,360 --> 04:52:27,760
BE AT LEAST DISCUSSED.

7812
04:52:27,760 --> 04:52:28,600
ONE WAS GENDER.

7813
04:52:28,600 --> 04:52:29,800
RESEARCH MORE IN GENDER.

7814
04:52:29,800 --> 04:52:37,400
I SAW SABB WELL REPRESENTED AND 

7815
04:52:37,400 --> 04:52:39,080
THAT'S IMPORTANT BUT MORE AND 

7816
04:52:39,080 --> 04:52:39,960
MORE ISSUES OF GENDER AS WELL 

7817
04:52:39,960 --> 04:52:40,640
SEX.

7818
04:52:40,640 --> 04:52:44,160
THAT'S ONE THING.

7819
04:52:44,160 --> 04:52:46,160
THE OTHER THING IS I SAW 

7820
04:52:46,160 --> 04:52:47,760
CONDITIONS THAT MOSTLY AFFECT 

7821
04:52:47,760 --> 04:52:50,400
WOMEN AND GIRLS WHICH IS AGAIN 

7822
04:52:50,400 --> 04:52:52,600
INCREDIBLY IMPORTANT BUT I 

7823
04:52:52,600 --> 04:52:57,160
DIDN'T SEE CHRONIC COMORBID 

7824
04:52:57,160 --> 04:52:58,360
CONDITIONS WE IDENTIFIED WHICH 

7825
04:52:58,360 --> 04:52:59,960
ARE DISEASES SUCH AS HEART 

7826
04:52:59,960 --> 04:53:01,480
DISEASE THAT AFFECT BOTH MEN AND

7827
04:53:01,480 --> 04:53:02,800
WOMEN BUT AFFECTS WOMEN IN 

7828
04:53:02,800 --> 04:53:04,160
UNIQUE WAYS.

7829
04:53:04,160 --> 04:53:07,720
I WANT TO MAKE SURE THESE 

7830
04:53:07,720 --> 04:53:09,000
DISEASES AND GENDER ARE NOT 

7831
04:53:09,000 --> 04:53:13,360
FORGOTTEN AND IF I MISSED IT, I 

7832
04:53:13,360 --> 04:53:15,520
APOLOGIZE BUT I THINK IT'S TOO 

7833
04:53:15,520 --> 04:53:16,200
IMPORTANT TO MENTION.

7834
04:53:16,200 --> 04:53:18,000
>>THANK YOU.

7835
04:53:18,000 --> 04:53:21,040
I BELIEVE GENDER WILL BE COVERED

7836
04:53:21,040 --> 04:53:24,920
BY CONTAIN THE AREA.

7837
04:53:24,920 --> 04:53:27,080
THAT IS -- IT'S ENCOMPASSING THE

7838
04:53:27,080 --> 04:53:28,600
DEFINITION OF WHAT GENDER MEANS 

7839
04:53:28,600 --> 04:53:32,600
AND ENVIRONMENTAL FACTORS AND 

7840
04:53:32,600 --> 04:53:34,600
SOCIAL FACTORS AS WELL.

7841
04:53:34,600 --> 04:53:37,000
THAT WILL BE TAKEN CARE OF.

7842
04:53:37,000 --> 04:53:38,960
THOSE ARE THE OVER ALL CONTENT 

7843
04:53:38,960 --> 04:53:40,120
AREAS BUT YOUR COMMENTS ARE VERY

7844
04:53:40,120 --> 04:53:44,280
WELL TAKEN AND WE'LL MAKE SURE 

7845
04:53:44,280 --> 04:53:46,200
WE ADDRESS THAT SO IS THE SECOND

7846
04:53:46,200 --> 04:53:49,280
AREA OF DEBILITATING HEALTH 

7847
04:53:49,280 --> 04:53:49,600
CONDITIONS.

7848
04:53:49,600 --> 04:53:51,080
THANK YOU SEARCH.

7849
04:53:51,080 --> 04:53:52,480
>>WHERE WAS THAT?

7850
04:53:52,480 --> 04:53:53,360
>>THE FIRST ONE.

7851
04:53:53,360 --> 04:53:56,320
THE GENDER WAS IN THE FIRST ONE.

7852
04:53:56,320 --> 04:53:57,520
>>NO -- 

7853
04:53:57,520 --> 04:54:00,160
>>THE DEBILITATING WILL
BE 

7854
04:54:00,160 --> 04:54:05,360
INCLUDED BUT IT'S NOT LISTED 

7855
04:54:05,360 --> 04:54:06,000
HERE.

7856
04:54:06,000 --> 04:54:08,680
AGAIN, THOSE ARE THE MAJOR AREAS

7857
04:54:08,680 --> 04:54:12,600
BUT NOT SPECIFIC AREAS THAT WILL

7858
04:54:12,600 --> 04:54:17,200
BE ADDRESSED LATER.

7859
04:54:17,200 --> 04:54:24,600
DR. SIMON AND THEN TEMPLETON AND

7860
04:54:24,600 --> 04:54:27,080
THEN SUDOWSKI.

7861
04:54:27,080 --> 04:54:28,720
>>TWO MINOR COMMENTS AND
ONE 

7862
04:54:28,720 --> 04:54:29,360
SUGGESTION.

7863
04:54:29,360 --> 04:54:32,240
PLEASE, CAN WE IN THE USE 

7864
04:54:32,240 --> 04:54:33,560
CULTURAL COMPETENCE.

7865
04:54:33,560 --> 04:54:38,120
NO ONE CAN EVER BE COMPETENT IN 

7866
04:54:38,120 --> 04:54:39,840
EVERYONE'S CULTURE.

7867
04:54:39,840 --> 04:54:42,840
CAN WE CONSIDER CULTURALLY 

7868
04:54:42,840 --> 04:54:44,600
RESPONSIVE FOR CULTURAL 

7869
04:54:44,600 --> 04:54:44,880
HUMILITY.

7870
04:54:44,880 --> 04:54:45,400
SOMETHING LIKE THAT?

7871
04:54:45,400 --> 04:54:47,720
THE OTHER THING IS I DON'T SEE 

7872
04:54:47,720 --> 04:54:48,880
THE DEFINITION OF WOMEN'S HEALTH

7873
04:54:48,880 --> 04:54:54,520
AND HOW TO CAPTURE THAT TO 

7874
04:54:54,520 --> 04:54:57,120
BETTER DELINEATE THE PROPORTION 

7875
04:54:57,120 --> 04:55:00,320
OF NIH FUNDS SPENT ON WOMEN'S 

7876
04:55:00,320 --> 04:55:00,560
HEALTH.

7877
04:55:00,560 --> 04:55:11,120
THE THIRD IS I DON'T SEE THE "A"

7878
04:55:14,080 --> 04:55:16,520
WORD, ABORTION AND THIS IS A 

7879
04:55:16,520 --> 04:55:18,640
HUGE ISSUE AND WE AS THE OFFICE 

7880
04:55:18,640 --> 04:55:20,640
OF RESEARCH IN WOMEN'S HEALTH 

7881
04:55:20,640 --> 04:55:24,400
ADVISORY COMMITTEE SHOULD NOT 

7882
04:55:24,400 --> 04:55:26,280
SHY AWAY FROM THE "A" WORD.

7883
04:55:26,280 --> 04:55:31,320
ABORTION CARE IS EVIDENCE-BASED 

7884
04:55:31,320 --> 04:55:33,560
THEY'RE SAFER THAN CAESAREAN 

7885
04:55:33,560 --> 04:55:36,360
SECTIONS AND A THIRD OF OUR 

7886
04:55:36,360 --> 04:55:41,040
PREGNANT PERSONS IN THIS COUNTRY

7887
04:55:41,040 --> 04:55:51,480
GET A CAESAREAN AND BLACK AND 

7888
04:55:51,480 --> 04:55:52,160
INDIGENOUS AND NATIVE AMERICAN 

7889
04:55:52,160 --> 04:55:54,160
WOMEN THIS IS ALARMING AND WITH 

7890
04:55:54,160 --> 04:55:56,640
DR. CLAYTON'S INITIAL 

7891
04:55:56,640 --> 04:55:58,760
PRESENTATION THIS MORNING WITH 

7892
04:55:58,760 --> 04:56:00,960
THE FOUR OUT OF FIVE MATERNAL 

7893
04:56:00,960 --> 04:56:03,320
DEATHS COULD BE PREVENTED, 

7894
04:56:03,320 --> 04:56:04,480
ABORTION CARE ACCESS IS ACTUALLY

7895
04:56:04,480 --> 04:56:07,880
ONE OF THOSE PREVENTIBLE DEATHS.

7896
04:56:07,880 --> 04:56:08,840
-- STRATEGIES.

7897
04:56:08,840 --> 04:56:12,160
IT NEEDS TO BE HERE AND NEEDS TO

7898
04:56:12,160 --> 04:56:15,120
BE SAID AND SPOKEN OUT LOUD.

7899
04:56:15,120 --> 04:56:15,560
THANKS.

7900
04:56:15,560 --> 04:56:17,360
>>I WANT TO ASK IF DR.
CLAYTON 

7901
04:56:17,360 --> 04:56:25,800
WANTS TO RESPOND TO THAT.

7902
04:56:25,800 --> 04:56:28,160
>>IN REPRODUCTIVE CARE
AND 

7903
04:56:28,160 --> 04:56:29,360
HEALTH CARE NEEDS TO BE INCLUDED

7904
04:56:29,360 --> 04:56:32,120
FOR SURE AND I GREATLY 

7905
04:56:32,120 --> 04:56:33,000
APPRECIATE YOUR COMMENTS AND WHY

7906
04:56:33,000 --> 04:56:36,280
WHERE YOU'RE COMING FROM AND 

7907
04:56:36,280 --> 04:56:38,080
THIS IS WHY WE HAVE THIS TIME 

7908
04:56:38,080 --> 04:56:39,640
TOGETHER TO HEAR DIRECTLY FROM 

7909
04:56:39,640 --> 04:56:41,760
YOU ALL AND THANK YOU SO MUCH.

7910
04:56:41,760 --> 04:56:43,680
WE REALLY APPRECIATE THAT.

7911
04:56:43,680 --> 04:56:44,760
>>DR. TEMPLETON.

7912
04:56:44,760 --> 04:56:47,000
>>THIS IS GREAT WORK.

7913
04:56:47,000 --> 04:56:50,240
MY COMMENTS WOULD BE TO WORK 

7914
04:56:50,240 --> 04:56:52,960
WITH DR. RIGENSTEINER AND SIMON.

7915
04:56:52,960 --> 04:56:55,960
I DIDN'T FIND WOMEN'S HEALTH BUT

7916
04:56:55,960 --> 04:56:57,200
WE DIDN'T DEFINE CHRONIC HEALTH 

7917
04:56:57,200 --> 04:56:58,160
CONDITIONS AND AS WE DISCUSSED 

7918
04:56:58,160 --> 04:56:59,920
AT THE MEETING LAST YEAR, THAT'S

7919
04:56:59,920 --> 04:57:02,280
ONE OF THE BIGGEST ISSUES IS 

7920
04:57:02,280 --> 04:57:03,240
WHAT IS A CHRONIC HEALTH 

7921
04:57:03,240 --> 04:57:04,840
CONDITION OF WOMEN UNLESS WE 

7922
04:57:04,840 --> 04:57:06,200
DEFINE IT WE DON'T KNOW WHAT 

7923
04:57:06,200 --> 04:57:07,120
WE'RE LOOKING FOR WHEN WE'RE 

7924
04:57:07,120 --> 04:57:08,680
LOOKING AT WHAT TO FUND AND HOW 

7925
04:57:08,680 --> 04:57:11,440
MUCH IS BEING FUNDED.

7926
04:57:11,440 --> 04:57:15,560
DR. RIGENSTEINER MENTIONED 

7927
04:57:15,560 --> 04:57:18,720
CARDIOVASCULAR DECEASE AND 

7928
04:57:18,720 --> 04:57:19,400
MUSCULOSKELETAL DISEASES ARE IN 

7929
04:57:19,400 --> 04:57:20,560
JUST ABOUT EVERYBODY.

7930
04:57:20,560 --> 04:57:21,920
IF WE CAN AT LEAST HAVE A 

7931
04:57:21,920 --> 04:57:24,280
DEFINITION OF WHAT A CHRONIC 

7932
04:57:24,280 --> 04:57:27,040
CONDITION IN A WOMAN IS AND HOW 

7933
04:57:27,040 --> 04:57:28,560
WHETHER THAT'S SOMETHING THAT'S 

7934
04:57:28,560 --> 04:57:30,320
EXCLUSIVELY IN WOMEN OR WOMEN 

7935
04:57:30,320 --> 04:57:31,680
AND MEN BUT JUST DIFFERENT IN 

7936
04:57:31,680 --> 04:57:33,560
WOMEN SO WE KNOW WHAT WE'RE 

7937
04:57:33,560 --> 04:57:34,680
LOOKING FOR.

7938
04:57:34,680 --> 04:57:40,600
AND MY OTHER COMMENT AND ONE OF 

7939
04:57:40,600 --> 04:57:44,600
THE PRIORITY IS WOMEN BEING 

7940
04:57:44,600 --> 04:57:45,920
HIRED AND SUPPORTING THEIR 

7941
04:57:45,920 --> 04:57:47,120
CAREERS AND BURNOUT.

7942
04:57:47,120 --> 04:57:49,760
I CONSIDER WE PUTTING A MENTION 

7943
04:57:49,760 --> 04:57:51,000
ON CAREER RE-ENTRY CONSIDERING 

7944
04:57:51,000 --> 04:57:52,600
THE NUMBER OF PEOPLE THAT LEFT 

7945
04:57:52,600 --> 04:57:54,760
THE WORKFORCE ESPECIALLY WOMEN 

7946
04:57:54,760 --> 04:57:56,560
DURING THE PANDEMIC AND ARE 

7947
04:57:56,560 --> 04:57:57,480
ANTICIPATED TO LEAVE IN THE NEXT

7948
04:57:57,480 --> 04:57:59,760
COUPLE OF YEARS, WOMEN IN 

7949
04:57:59,760 --> 04:58:02,080
PARTICULAR BECAUSE OF OUR 

7950
04:58:02,080 --> 04:58:02,760
SOCIETAL GENDERED EXPECTATIONS 

7951
04:58:02,760 --> 04:58:05,920
AT HOME MAY HAVE MORE ISSUES 

7952
04:58:05,920 --> 04:58:06,960
RE-ENTERING THE WORKFORCE AND 

7953
04:58:06,960 --> 04:58:08,400
WHILE WE NEED TO CONTINUE TO 

7954
04:58:08,400 --> 04:58:10,680
TRAIN WOMEN IN SCIENCE CAREERS, 

7955
04:58:10,680 --> 04:58:12,480
IT'S ALMOST A FASTER TRACK TO 

7956
04:58:12,480 --> 04:58:14,480
RETRAIN WOMEN AND SUPPORT THEM 

7957
04:58:14,480 --> 04:58:16,600
TO GET THEIR CAREERS BACK ON 

7958
04:58:16,600 --> 04:58:17,160
TRACK.

7959
04:58:17,160 --> 04:58:19,560
SO I WOULD ASK WE ALSO CONSIDER 

7960
04:58:19,560 --> 04:58:21,040
THAT AS ANOTHER AREA WHERE WE 

7961
04:58:21,040 --> 04:58:21,960
WANT TO TRY TO SUPPORT WOMEN AND

7962
04:58:21,960 --> 04:58:25,480
SCIENCES.

7963
04:58:25,480 --> 04:58:26,280
>>THANK YOU.

7964
04:58:26,280 --> 04:58:32,600
>>THANK YOU, DR.
TEMPLETON.

7965
04:58:32,600 --> 04:58:33,280
DR. SUDOWSKI.

7966
04:58:33,280 --> 04:58:36,000
>>THE REPORT IS CREATE
AND THE 

7967
04:58:36,000 --> 04:58:36,920
DISCUSSION WAS INSIGHTFUL.

7968
04:58:36,920 --> 04:58:38,840
ONE OF THE THINGS I LIKE THE 

7969
04:58:38,840 --> 04:58:44,640
MOST ABOUT THE OVER ALL APPROACH

7970
04:58:44,640 --> 04:58:45,640
IS THE DIMENSIONALITY.

7971
04:58:45,640 --> 04:58:47,280
THE PROPOSED STUDIES REALLY 

7972
04:58:47,280 --> 04:58:49,440
FOCUS ON ANYTHING AND FOCUS MORE

7973
04:58:49,440 --> 04:58:51,840
ON THE PREGNANCY AREA BECAUSE 

7974
04:58:51,840 --> 04:58:53,320
THIS IS THE ONE AREA I 

7975
04:58:53,320 --> 04:58:54,520
CONTRIBUTED MORE TO AND 

7976
04:58:54,520 --> 04:58:57,200
EVERYTHING MORE FROM COMMUNITY 

7977
04:58:57,200 --> 04:58:58,240
HEALTH CARE TO HOSPITAL LABOR 

7978
04:58:58,240 --> 04:59:00,600
AND DELIVERY AND PREGNANCY TO 

7979
04:59:00,600 --> 04:59:08,680
THE POSTPARTUM PERIOD AND DOW  

7980
04:59:08,680 --> 04:59:11,280
DOULAS AND NURSES AND GOING FROM

7981
04:59:11,280 --> 04:59:20,880
BASIC TO TRANSLATION TO RESEARCH

7982
04:59:20,880 --> 04:59:26,760
CLINICAL RESEARCH AND ONE PLACE 

7983
04:59:26,760 --> 04:59:28,400
WHERE IT'S READ AND THERE'S 

7984
04:59:28,400 --> 04:59:29,240
RESEARCH OPPORTUNITIES.

7985
04:59:29,240 --> 04:59:30,880
ON PAGE 49 THERE'S RESEARCH 

7986
04:59:30,880 --> 04:59:32,160
OPPORTUNITIES DISCUSSION FOR 

7987
04:59:32,160 --> 04:59:33,960
THREE MAJOR AREAS, CERVICAL 

7988
04:59:33,960 --> 04:59:37,960
CANCER, CHRONIC DISEASES AND 

7989
04:59:37,960 --> 04:59:41,720
MATERNAL MORBIDITY, MORTALITY, 

7990
04:59:41,720 --> 04:59:44,400
IT DID NOT INCLUDE BASIC AND 

7991
04:59:44,400 --> 04:59:45,320
TRANSLATIONAL RESEARCH, THE 

7992
04:59:45,320 --> 04:59:49,360
OTHER TWO DID.

7993
04:59:49,360 --> 04:59:50,560
I KNOW BASIC TRANSLATIONAL 

7994
04:59:50,560 --> 04:59:52,600
RESEARCH IS VERY GOOD BUT IN THE

7995
04:59:52,600 --> 04:59:55,440
PLACE OF RECOMMENDATION FOR SOME

7996
04:59:55,440 --> 04:59:57,120
REASON BASIC AND TRANSLATIONAL 

7997
04:59:57,120 --> 05:00:01,080
RESEARCH IN MATERNAL HEALTH WAS 

7998
05:00:01,080 --> 05:00:01,560
OMITTED.

7999
05:00:01,560 --> 05:00:02,720
I'M NOT SURE WHY.

8000
05:00:02,720 --> 05:00:05,040
IT'S IMPORTANT TO HAVE SOME 

8001
05:00:05,040 --> 05:00:11,960
CONDITIONS THAT CAN REALLY BE 

8002
05:00:11,960 --> 05:00:14,200
OPTIMALLY ADDRESSED BY BASIC 

8003
05:00:14,200 --> 05:00:14,480
RESEARCH.

8004
05:00:14,480 --> 05:00:15,560
>>THANK YOU.

8005
05:00:15,560 --> 05:00:16,600
I WILL SUMMARIZE ALL THE 

8006
05:00:16,600 --> 05:00:17,680
COMMENTS I HEARD BUT I WANTED TO

8007
05:00:17,680 --> 05:00:19,600
PUT IN FRONT OF YOU ALL THE 

8008
05:00:19,600 --> 05:00:21,360
CROSS-CUTTING TOPICS BECAUSE 

8009
05:00:21,360 --> 05:00:24,040
SOME OF THE TOPICS PEOPLE ARE 

8010
05:00:24,040 --> 05:00:26,640
ASKING ABOUT ARE SPECIFICALLY 

8011
05:00:26,640 --> 05:00:27,000
HERE LISTED.

8012
05:00:27,000 --> 05:00:28,680
THIS DID COME UP AND THEY'LL BE 

8013
05:00:28,680 --> 05:00:31,040
CONSIDERED FOR SURE.

8014
05:00:31,040 --> 05:00:36,360
I THINK DR. HIGGINS, I SAW YOUR 

8015
05:00:36,360 --> 05:00:37,400
COMMENT AND YOU CAN SEE 

8016
05:00:37,400 --> 05:00:40,960
SUBSTANCE USE AND MISUSE IS 

8017
05:00:40,960 --> 05:00:41,520
RIGHT HERE.

8018
05:00:41,520 --> 05:00:43,800
DR. AMENIA.

8019
05:00:43,800 --> 05:00:47,120
>>THANK YOU, I WANTED TO
DO A 

8020
05:00:47,120 --> 05:00:49,760
BRIEF INCLUSION BECAUSE I KNOW 

8021
05:00:49,760 --> 05:00:50,680
THE FIRST BULLET WHEN WE TALK 

8022
05:00:50,680 --> 05:00:52,400
ABOUT DISEASES THAT AFFECT AND 

8023
05:00:52,400 --> 05:00:53,680
ALSO HEALTH CONDITIONS.

8024
05:00:53,680 --> 05:00:58,640
I THINK ABOUT MENOPAUSE THAT 

8025
05:00:58,640 --> 05:00:59,440
DIDN'T HIT THE PRIORITY AREAS 

8026
05:00:59,440 --> 05:01:00,600
I'D LOVE TO MAKE SURE IS 

8027
05:01:00,600 --> 05:01:01,080
ADDRESSED.

8028
05:01:01,080 --> 05:01:03,560
>>GREAT.

8029
05:01:03,560 --> 05:01:07,960
THANK YOU.

8030
05:01:07,960 --> 05:01:12,840
DO I SEE A HAND UP AGAIN?

8031
05:01:12,840 --> 05:01:15,560
>>TALK ABOUT PHRASES THAT

8032
05:01:15,560 --> 05:01:18,280
BECAME FAMOUS DURING COVID, 

8033
05:01:18,280 --> 05:01:21,400
YOU'RE ON MUTE IS A BIG ONE.

8034
05:01:21,400 --> 05:01:23,000
SO, HERE'S WHERE I DIFFERED FROM

8035
05:01:23,000 --> 05:01:24,680
WHAT WAS SAID.

8036
05:01:24,680 --> 05:01:27,400
IT SAYS DISEASES THAT 

8037
05:01:27,400 --> 05:01:28,960
PREDOMINANTLY AFFECT WOMEN AND 

8038
05:01:28,960 --> 05:01:29,160
GIRLS.

8039
05:01:29,160 --> 05:01:32,120
OF COURSE WE NEED TO STUDY THOSE

8040
05:01:32,120 --> 05:01:34,280
DISEASES BUTTING SHOULD BE 

8041
05:01:34,280 --> 05:01:35,720
PHRASED DISEASES THAT 

8042
05:01:35,720 --> 05:01:36,480
PREDOMINANTLY AFFECT OR SOMEHOW 

8043
05:01:36,480 --> 05:01:37,840
PUT IN THERE IT'S NOT JUST 

8044
05:01:37,840 --> 05:01:40,320
DISEASE PREDOMINANTLY AFFECT 

8045
05:01:40,320 --> 05:01:41,800
WOMEN AND GIRLS BUT ALSO 

8046
05:01:41,800 --> 05:01:45,560
DISEASES THAT MAY UNIQUELY 

8047
05:01:45,560 --> 05:01:50,560
AFFECT WOMEN AND GIRLS LIKE 

8048
05:01:50,560 --> 05:01:51,800
ORTHOPEDIC ISSUES AND I'M 

8049
05:01:51,800 --> 05:01:53,800
COMFORTED BY THE WORDING OF 

8050
05:01:53,800 --> 05:01:54,000
THAT.

8051
05:01:54,000 --> 05:01:54,240
>>OKAY.

8052
05:01:54,240 --> 05:02:00,440
WELL TAKEN.

8053
05:02:00,440 --> 05:02:01,760
DR. JONES.

8054
05:02:01,760 --> 05:02:04,640
>>ONE OF THE THINGS I
HAVEN'T 

8055
05:02:04,640 --> 05:02:06,720
SEEN REPRESENTED HERE THAT I 

8056
05:02:06,720 --> 05:02:10,480
JUST INVITE US TO THINK ABOUT IS

8057
05:02:10,480 --> 05:02:12,080
THE DIAD.

8058
05:02:12,080 --> 05:02:12,960
THE BIRTHING PERSON WOMAN AND 

8059
05:02:12,960 --> 05:02:18,520
CHILD.

8060
05:02:18,520 --> 05:02:21,320
AND THEY'RE LIKELY TO HAVE 

8061
05:02:21,320 --> 05:02:22,360
HEALTHY NEXT GENERATION.

8062
05:02:22,360 --> 05:02:26,120
IS THERE SOME WAY THAT THAT 

8063
05:02:26,120 --> 05:02:27,600
COULD BE REPRESENTED BECAUSE I 

8064
05:02:27,600 --> 05:02:28,800
THINK OFTEN WE JUST FOCUS ON THE

8065
05:02:28,800 --> 05:02:33,040
INDIVIDUAL AND YOU CAN'T HAVE A 

8066
05:02:33,040 --> 05:02:34,400
BABY WITHOUT A PERSON AND ADULT 

8067
05:02:34,400 --> 05:02:34,640
THERE.

8068
05:02:34,640 --> 05:02:37,480
I INVITE US TO THINK HOW THAT 

8069
05:02:37,480 --> 05:02:40,400
MIGHT BE WOVEN IN.

8070
05:02:40,400 --> 05:02:41,200
>>OKAY.

8071
05:02:41,200 --> 05:02:43,600
ANY OTHER COMMENTS BEFORE I 

8072
05:02:43,600 --> 05:02:54,040
SUMMARIZE WHAT I'VE HEARD?

8073
05:03:00,400 --> 05:03:03,160
CHRONIC DEBILITATING CONDITIONS 

8074
05:03:03,160 --> 05:03:04,120
TO BE INCLUDED.

8075
05:03:04,120 --> 05:03:09,600
ALSO NOT DISEASES BUT AREAS SUCH

8076
05:03:09,600 --> 05:03:14,280
AS MENOPAUSE, ABORTION TOPIC AND

8077
05:03:14,280 --> 05:03:15,920
DISEASES THAT ARE SPECIFIC TO 

8078
05:03:15,920 --> 05:03:23,240
WOMEN NOT JUST DOMINANTLY WOMEN 

8079
05:03:23,240 --> 05:03:24,600
DR. SIMON, YOU HAVE ONE MORE?

8080
05:03:24,600 --> 05:03:26,120
>>I'M SORRY.

8081
05:03:26,120 --> 05:03:28,600
WE KEEP SAYING HOW IT AFFECTS 

8082
05:03:28,600 --> 05:03:29,880
THE HEALTH OF WOMEN AND I JUST 

8083
05:03:29,880 --> 05:03:32,160
WANT TO PIGGY BACK ON WHAT 

8084
05:03:32,160 --> 05:03:32,920
DR. JONES JUST SAID.

8085
05:03:32,920 --> 05:03:34,760
IT'S NOT JUST THE HEALTH OF 

8086
05:03:34,760 --> 05:03:37,080
WOMEN AND THE BABY THAT SHE'S 

8087
05:03:37,080 --> 05:03:42,120
CARRYING BUT THE HEALTH OF 

8088
05:03:42,120 --> 05:03:43,640
SOCIETY.

8089
05:03:43,640 --> 05:03:44,960
AND THE COMMUNITY FAMILY AND 

8090
05:03:44,960 --> 05:03:45,200
SOCIETY.

8091
05:03:45,200 --> 05:03:49,560
IF THERE'S A WAY TO DO THAT TOO 

8092
05:03:49,560 --> 05:03:54,400
BECAUSE WHEN WE STOP DEBATING ON

8093
05:03:54,400 --> 05:03:56,320
THINGS LIKE THE "A" WORD WHEN 

8094
05:03:56,320 --> 05:03:58,640
IT'S NOT SO POLITICALLY CHARGED,

8095
05:03:58,640 --> 05:04:02,560
IT BECOMES, IF WE CAN FRAME 

8096
05:04:02,560 --> 05:04:04,760
WOMEN'S HEALTH IN THE BENEFIT TO

8097
05:04:04,760 --> 05:04:09,400
THE GREATER GOOD I THINK IT WILL

8098
05:04:09,400 --> 05:04:11,920
HELP THE STRATEGIC PLAN AND THE 

8099
05:04:11,920 --> 05:04:12,240
NORTH STAR.

8100
05:04:12,240 --> 05:04:13,760
>>I GOT IT.

8101
05:04:13,760 --> 05:04:15,040
DID I MISS ANYTHING?

8102
05:04:15,040 --> 05:04:18,040
I JUST WANT TO MAKE SURE I MAKE 

8103
05:04:18,040 --> 05:04:19,440
IT VERY CLEAR THIS INPUT 

8104
05:04:19,440 --> 05:04:23,000
RECEIVED IS INPUT THAT CAME FROM

8105
05:04:23,000 --> 05:04:24,480
ALL THESE INFORMANTS.

8106
05:04:24,480 --> 05:04:27,600
WE GATHERED ALL THIS 

8107
05:04:27,600 --> 05:04:28,280
INFORMATION.

8108
05:04:28,280 --> 05:04:32,800
THIS IS THE RESULT OF HEARING SO

8109
05:04:32,800 --> 05:04:33,120
MANY PEOPLE.

8110
05:04:33,120 --> 05:04:36,600
THE TOPICS THAT ARE COMING RIGHT

8111
05:04:36,600 --> 05:04:38,160
NOW WERE HEARD BUT PROBABLY WERE

8112
05:04:38,160 --> 05:04:41,000
NOT HEARD WHEN WE HAD THE 

8113
05:04:41,000 --> 05:04:41,800
KICKOFF MEETING MAYBE.

8114
05:04:41,800 --> 05:04:43,160
WE HAVE DIFFERENT MEMBERS.

8115
05:04:43,160 --> 05:04:48,200
I JUST WANT TO MAKE SURE THIS IS

8116
05:04:48,200 --> 05:04:51,360
NOT SOMETHING DR. SHIEH AND 

8117
05:04:51,360 --> 05:04:53,240
DR. CHANDLER PUT TOGETHER, IT'S 

8118
05:04:53,240 --> 05:04:55,120
A RESULT OF ALL THE INFORMATION 

8119
05:04:55,120 --> 05:04:58,880
GATHERED BUT ALL YOUR COMMENTS 

8120
05:04:58,880 --> 05:05:00,080
ARE TAKEN INTO CONSIDERATION.

8121
05:05:00,080 --> 05:05:02,760
THIS IS A DRAFT OF THE AREAS.

8122
05:05:02,760 --> 05:05:06,840
THOSE ARE NOT THE GOALS OR 

8123
05:05:06,840 --> 05:05:07,440
OBJECTIVES.

8124
05:05:07,440 --> 05:05:10,600
THESE ARE THE MAIN AREAS FROM 

8125
05:05:10,600 --> 05:05:12,080
THE INPUT RECEIVED SO FAR.

8126
05:05:12,080 --> 05:05:18,440
SO ALL YOUR COMMENTS ARE WELL 

8127
05:05:18,440 --> 05:05:18,640
TAKEN.

8128
05:05:18,640 --> 05:05:20,560
WE'LL TAKE THEM INTO ENSURING 

8129
05:05:20,560 --> 05:05:22,520
THOSE AREAS ARE INCORPORATED 

8130
05:05:22,520 --> 05:05:25,880
INTO THE BIG TOPICS THAT WE ARE 

8131
05:05:25,880 --> 05:05:27,320
PUTTING IN FRONT OF OUR THINK 

8132
05:05:27,320 --> 05:05:30,000
TANKS TO DEVELOP THE GOALS AND 

8133
05:05:30,000 --> 05:05:32,040
OBJECTIVES MOVING FORWARD.

8134
05:05:32,040 --> 05:05:36,320
>>DR. NOURSI, TO
SUMMARIZE THE 

8135
05:05:36,320 --> 05:05:37,480
TOPICS YOU DID NOT SUMMARIZE 

8136
05:05:37,480 --> 05:05:39,560
WHAT I SAID ABOUT BASIC AND 

8137
05:05:39,560 --> 05:05:42,360
TRANSLATIONAL RESEARCH.

8138
05:05:42,360 --> 05:05:43,600
>>THANK YOU.

8139
05:05:43,600 --> 05:05:46,400
THERE'S SOMETHING I MISSED IS 

8140
05:05:46,400 --> 05:05:50,200
ALL GOING TO BE IN OUR COMMENT 

8141
05:05:50,200 --> 05:05:52,080
IN THE SUMMARY AND RECORDING OF 

8142
05:05:52,080 --> 05:05:52,520
THE MEETING.

8143
05:05:52,520 --> 05:05:54,120
>>THANK YOU ALL.

8144
05:05:54,120 --> 05:05:55,200
THANK YOU, FOR LEADING THAT.

8145
05:05:55,200 --> 05:05:57,400
I WANT TO THANK EVERYONE FOR 

8146
05:05:57,400 --> 05:05:57,920
YOUR INPUT.

8147
05:05:57,920 --> 05:06:00,560
IT'S VERY IMPORTANT AND HELPFUL 

8148
05:06:00,560 --> 05:06:02,360
TO US.

8149
05:06:02,360 --> 05:06:04,080
THANK YOU, SAMIA.

8150
05:06:04,080 --> 05:06:05,840
>>WITH TAKING INTO 

8151
05:06:05,840 --> 05:06:06,880
CONSIDERATION ALL THE COMMENTS, 

8152
05:06:06,880 --> 05:06:09,320
I WOULD LIKE TO MOVE ON TO VOTE 

8153
05:06:09,320 --> 05:06:12,720
TO BECAUSE WITH THAT WE CAN MOVE

8154
05:06:12,720 --> 05:06:20,040
TO THE AREA OF MOVING FORWARD TO

8155
05:06:20,040 --> 05:06:21,600
WORKING ON THOSE AND POLISHING 

8156
05:06:21,600 --> 05:06:23,840
THEM UP.

8157
05:06:23,840 --> 05:06:27,080
AT THIS TIME I WOULD LIKE TO 

8158
05:06:27,080 --> 05:06:31,200
VOTE ON APPROVING THOSE TOPIC 

8159
05:06:31,200 --> 05:06:32,600
AREAS WITH THE COMMENTS THAT 

8160
05:06:32,600 --> 05:06:34,680
WERE RECEIVED THAT WILL BE 

8161
05:06:34,680 --> 05:06:36,640
INCORPORATED INTO THE REVISIONS 

8162
05:06:36,640 --> 05:06:47,160
THAT WE WILL BE PUTTING FORWARD.

8163
05:06:49,760 --> 05:07:00,240
AND WE ARE ADDING AND THERE'S A 

8164
05:07:02,720 --> 05:07:05,000
POLL OPENING RIGHT NOW.

8165
05:07:05,000 --> 05:07:08,640
>>WE NEED TO HAVE A
MEMBER MAKE

8166
05:07:08,640 --> 05:07:11,200
THE MOTION.

8167
05:07:11,200 --> 05:07:13,400
>>WE WOULD LIKE TO HAVE A

8168
05:07:13,400 --> 05:07:15,600
MOTION ON THE TABLE TO APPROVE 

8169
05:07:15,600 --> 05:07:18,760
THE DRAFT CONTENT AREA FOR THE 

8170
05:07:18,760 --> 05:07:21,760
2024, 2028, NIH-WIDE STRATEGIC 

8171
05:07:21,760 --> 05:07:23,000
PLAN ON THE RESEARCH ON THE 

8172
05:07:23,000 --> 05:07:23,880
HEALTH OF WOMEN.

8173
05:07:23,880 --> 05:07:32,240
DO WE HAVE A MOTION?

8174
05:07:32,240 --> 05:07:40,400
>>A MOTION TO ADOPT THE
DRAFT 

8175
05:07:40,400 --> 05:07:40,600
PLAN.

8176
05:07:40,600 --> 05:07:43,680
>>DO I HAVE A SECOND.

8177
05:07:43,680 --> 05:07:44,440
THANK YOU.

8178
05:07:44,440 --> 05:07:45,760
WE'RE OPENING THE POLL.

8179
05:07:45,760 --> 05:07:49,520
IF YOU'RE IN FAVOR, OPPOSE OR 

8180
05:07:49,520 --> 05:07:49,760
ABSTAIN.

8181
05:07:49,760 --> 05:07:51,320
ENTER YOUR RESPONSE AND WE'LL 

8182
05:07:51,320 --> 05:08:01,800
HAVE 30 SECONDS TO RESPOND.

8183
05:08:26,400 --> 05:08:30,080
>>THANK YOU WE APPRECIATE
YOUR 

8184
05:08:30,080 --> 05:08:31,160
LIVELY DISCUSSION AND COMMENTS 

8185
05:08:31,160 --> 05:08:33,600
AND WE HAVE A GREAT TEAM HERE AT

8186
05:08:33,600 --> 05:08:36,400
ORWH THAT WILL ENSURE ALL YOUR 

8187
05:08:36,400 --> 05:08:41,640
COMMENTS ARE TAKEN INTO 

8188
05:08:41,640 --> 05:08:42,640
CONSIDERATION AND OUR STRATEGIC 

8189
05:08:42,640 --> 05:08:44,400
PLAN SPECIFIC AREAS TO MOVE 

8190
05:08:44,400 --> 05:08:47,240
FORWARD TO THE THINK TANKS ARE 

8191
05:08:47,240 --> 05:08:47,480
ADDRESSED.

8192
05:08:47,480 --> 05:08:51,640
WITH THAT, I WOULD LIKE TO 

8193
05:08:51,640 --> 05:08:57,120
WELCOME DR. SARAH TEMPKIN TO 

8194
05:08:57,120 --> 05:08:59,240
INTRODUCE OUR NEXT SPEAKER.

8195
05:08:59,240 --> 05:09:00,280
>>THANK YOU SO MUCH, 

8196
05:09:00,280 --> 05:09:01,400
DR. NOURSI.

8197
05:09:01,400 --> 05:09:06,200
I'M SO HAPPY TO PRESENT AND 

8198
05:09:06,200 --> 05:09:07,320
INTRODUCE DR. ELIZABETH BARR WHO

8199
05:09:07,320 --> 05:09:08,600
WILL BE OUR NEXT PRESENTER.

8200
05:09:08,600 --> 05:09:12,600
SHE'S A SOCIAL AND BEHAVIORAL 

8201
05:09:12,600 --> 05:09:16,680
SCIENCE ADMINISTRATOR AT ORWH.

8202
05:09:16,680 --> 05:09:20,040
DR. BARR COORDINATES OUR ORWH 

8203
05:09:20,040 --> 05:09:20,640
INTERPROFESSIONAL EDUCATION 

8204
05:09:20,640 --> 05:09:23,000
EFFORTS AND CO-LEADS THE DIVERSE

8205
05:09:23,000 --> 05:09:24,200
VOICES SPEAKER SERIES AND 

8206
05:09:24,200 --> 05:09:25,680
SUPPORTS EFFORTS RELATED TO 

8207
05:09:25,680 --> 05:09:26,360
GENDER VARIABLES IN HEALTH 

8208
05:09:26,360 --> 05:09:26,920
RESEARCH.

8209
05:09:26,920 --> 05:09:29,880
HER BACKGROUND IS IN 

8210
05:09:29,880 --> 05:09:31,200
COMMUNITY-CENTERED RESEARCH, HIV

8211
05:09:31,200 --> 05:09:33,120
TREATMENT, REPRODUCTIVE JUSTICE 

8212
05:09:33,120 --> 05:09:35,440
AND GENDER-BASED VIOLENCE.

8213
05:09:35,440 --> 05:09:37,360
DR. BARR COMPLETED HER Ph.D. IN 

8214
05:09:37,360 --> 05:09:38,240
COMMUNICATION WITH TRAINING AND 

8215
05:09:38,240 --> 05:09:39,640
SCIENCE AND TECHNOLOGY STUDIES 

8216
05:09:39,640 --> 05:09:41,200
AT THE UNIVERSITY OF WISCONSIN 

8217
05:09:41,200 --> 05:09:43,400
MADSON AND HER MASTER'S DEGREE 

8218
05:09:43,400 --> 05:09:46,600
IN WOMEN'S AND GENDER STUDIES AT

8219
05:09:46,600 --> 05:09:47,760
TOWSON UNIVERSITY.

8220
05:09:47,760 --> 05:09:50,480
PRYOR TO JOINING ORWH IN 2019, 

8221
05:09:50,480 --> 05:09:51,960
DR. BARR LED INTERDISCIPLINARY 

8222
05:09:51,960 --> 05:09:54,520
AND CROSS-PROJECTS TO INFECTIOUS

8223
05:09:54,520 --> 05:09:56,280
WOMEN'S ENGAGEMENT IN CLINICAL 

8224
05:09:56,280 --> 05:09:57,600
RESEARCH AND SERVED ON THE 

8225
05:09:57,600 --> 05:10:01,320
FACULTY AT UMBC AND TOWSON 

8226
05:10:01,320 --> 05:10:02,520
UNIVERSITY.

8227
05:10:02,520 --> 05:10:09,320
WELCOME, DR. BARR.

8228
05:10:09,320 --> 05:10:11,800
>>THANK YOU.

8229
05:10:11,800 --> 05:10:15,520
I WANT TO RESPOND TO A QUESTION 

8230
05:10:15,520 --> 05:10:17,200
RAISED EARLIER REGARDING 

8231
05:10:17,200 --> 05:10:19,400
COMMUNITY-DRIVEN RESEARCH.

8232
05:10:19,400 --> 05:10:22,080
WITH ORWH'S R35 PROGRAM HOPES TO

8233
05:10:22,080 --> 05:10:23,840
RECEIVE APPLICATIONS FROM 

8234
05:10:23,840 --> 05:10:25,240
COMMUNITY-BASED ORGANIZATION 

8235
05:10:25,240 --> 05:10:27,680
NONPROFITS AND ADVOCACY GROUPS 

8236
05:10:27,680 --> 05:10:29,000
AND ENCOURAGE PROJECTS FOCUS ON 

8237
05:10:29,000 --> 05:10:30,880
ADVOCACY AND COMMUNITY-BASED 

8238
05:10:30,880 --> 05:10:32,600
EDUCATION SO I WANTED TO MAKE 

8239
05:10:32,600 --> 05:10:42,400
THAT QUICK NOTE.

8240
05:10:42,400 --> 05:10:45,680
WE KNOW BIOLOGY, SOCIETY AND 

8241
05:10:45,680 --> 05:10:47,080
POLICY INFLUENCE HEALTH, 

8242
05:10:47,080 --> 05:10:47,960
CONSIDERATION OF GENDER IN 

8243
05:10:47,960 --> 05:10:53,200
RESEARCH IS CRITICAL TO 

8244
05:10:53,200 --> 05:10:56,920
ADVANCING THE NIH MISSION OF 

8245
05:10:56,920 --> 05:11:01,600
INCREASING HEALTH AND SEX AND 

8246
05:11:01,600 --> 05:11:04,320
GENDER ARE OFTEN USED THEY 

8247
05:11:04,320 --> 05:11:07,120
DESCRIBE UNIQUE HEALTH IMPACTS 

8248
05:11:07,120 --> 05:11:12,600
AND USING THE TERMS 

8249
05:11:12,600 --> 05:11:14,320
INTERCHANGEABLY CONTRIBUTES TO 

8250
05:11:14,320 --> 05:11:15,600
CONFUSION AND SEX IS A CONSTRUCT

8251
05:11:15,600 --> 05:11:18,920
BASED ON A SET OF TRAITS 

8252
05:11:18,920 --> 05:11:20,400
DESCRIBED AS SEX TRAITS THAT 

8253
05:11:20,400 --> 05:11:22,360
INCLUDE ANATOMY, PHYSIOLOGY, 

8254
05:11:22,360 --> 05:11:23,920
GENETICS AND HORMONES.

8255
05:11:23,920 --> 05:11:26,600
ALL ANIMALS INCLUDING HUMANS 

8256
05:11:26,600 --> 05:11:27,680
HAVE A SEX.

8257
05:11:27,680 --> 05:11:31,200
WHILE MALE OR FEMALE DESCRIBED 

8258
05:11:31,200 --> 05:11:34,360
SEX VARIATIONS OCCUR IN WHICH 

8259
05:11:34,360 --> 05:11:39,680
SEX TRAITS DO NOT CORRESPOND TO 

8260
05:11:39,680 --> 05:11:42,240
A BIOLOGICAL SEX.

8261
05:11:42,240 --> 05:11:46,000
THE LANDMARK 2016 SEX AS A 

8262
05:11:46,000 --> 05:11:47,920
BIOLOGICAL VARIABLE POLICY HAS 

8263
05:11:47,920 --> 05:11:50,560
THE EXPECTATION THAT SEX AS A 

8264
05:11:50,560 --> 05:11:51,680
BIOLOGICAL VARIABLE BE FACTORED 

8265
05:11:51,680 --> 05:11:54,000
INTO RESEARCH DESIGN, ANALYSIS 

8266
05:11:54,000 --> 05:11:55,920
AND REPORTING IN HUMAN AND 

8267
05:11:55,920 --> 05:11:57,120
VERTEBRATE ANIMAL STUDIES.

8268
05:11:57,120 --> 05:12:01,080
GENDER IS A SOCIAL AND CULTURAL 

8269
05:12:01,080 --> 05:12:04,040
VARIABLE THAT ENCOMPASSES 

8270
05:12:04,040 --> 05:12:05,160
DOMAINS EACH OF WHICH INFLUENCE 

8271
05:12:05,160 --> 05:12:09,680
GENDER IDENTITY AND EXPRESSION 

8272
05:12:09,680 --> 05:12:12,240
AND NORMS AND STRUCK USUAL 

8273
05:12:12,240 --> 05:12:14,720
SEXISM, POWER AND EQUITY.

8274
05:12:14,720 --> 05:12:19,400
GENDER SOCIALIZATION AND NORMS 

8275
05:12:19,400 --> 05:12:21,680
OF MASCULINITY INFLUENCE BOYS' 

8276
05:12:21,680 --> 05:12:26,160
AND MEN'S BEHAVIORS AND CAN 

8277
05:12:26,160 --> 05:12:28,080
CONTRIBUTE TO HEALTH INEQUITY.

8278
05:12:28,080 --> 05:12:29,400
OTHER SOCIAL VARIABLES INCLUDING

8279
05:12:29,400 --> 05:12:31,600
RACE, ETHNICITY AND SOCIO 

8280
05:12:31,600 --> 05:12:33,160
ECONOMIC STATUS, STATE AND 

8281
05:12:33,160 --> 05:12:35,600
FEDERAL POLICIES MAY 

8282
05:12:35,600 --> 05:12:37,960
ADDITIONALLY INTERACT WITH 

8283
05:12:37,960 --> 05:12:38,760
GENDER HIGHLIGHTING THE 

8284
05:12:38,760 --> 05:12:49,160
IMPORTANCE OF AN INTERAGENCY 

8285
05:12:49,160 --> 05:12:49,880
APPROACH AND THERE'S WAYS TO 

8286
05:12:49,880 --> 05:12:51,600
ADDRESS THE VARIABLES IN 

8287
05:12:51,600 --> 05:12:52,040
RESEARCH.

8288
05:12:52,040 --> 05:12:53,960
THE CANADIAN INSTITUTES OF 

8289
05:12:53,960 --> 05:12:57,600
HEALTH RESEARCH HAS A SEX AND 

8290
05:12:57,600 --> 05:12:59,040
GENDER-BASED ANALYSIS PLUS 

8291
05:12:59,040 --> 05:13:02,240
POLICY WHICH CAME INTO AFFECT IN

8292
05:13:02,240 --> 05:13:06,200
JULY OF 2009.

8293
05:13:06,200 --> 05:13:11,640
IT'S TO ADDRESS HOW FACTORS LIKE

8294
05:13:11,640 --> 05:13:13,080
DISABILITY AND SEXUAL 

8295
05:13:13,080 --> 05:13:14,160
ORIENTATION AND CULTURAL 

8296
05:13:14,160 --> 05:13:16,040
BACKGROUND AND MIGRATION STATUS 

8297
05:13:16,040 --> 05:13:17,840
AND GEOGRAPHIC LOCATION INTERACT

8298
05:13:17,840 --> 05:13:20,600
AND INTERSECT WITH BROADER 

8299
05:13:20,600 --> 05:13:23,200
SYSTEMS OF POWER.

8300
05:13:23,200 --> 05:13:24,520
THE EUROPEAN COMMISSION WHICH IS

8301
05:13:24,520 --> 05:13:27,720
THE E.U.'S KEY FUNDING PROGRAM 

8302
05:13:27,720 --> 05:13:30,920
FOR INNOVATION DESCRIBES THE 

8303
05:13:30,920 --> 05:13:33,760
GENDER DIMENSION IN RESEARCH IS 

8304
05:13:33,760 --> 05:13:40,600
A REQUIREMENT BY DEFAULT.

8305
05:13:40,600 --> 05:13:43,120
DISENTANGLED THE SEX AND GENDER 

8306
05:13:43,120 --> 05:13:44,800
IN HEALTH HAS BEEN LIMITED TO 

8307
05:13:44,800 --> 05:13:45,200
DATE.

8308
05:13:45,200 --> 05:13:46,320
THE CURRENT NIH REQUIREMENT FOR 

8309
05:13:46,320 --> 05:13:48,080
RESEARCH ON HUMAN SUBJECTS IS 

8310
05:13:48,080 --> 05:13:50,680
REFLECTION OF ONE VARIABLE, SEX 

8311
05:13:50,680 --> 05:13:52,200
WHETHER SELF-REPORTED BY 

8312
05:13:52,200 --> 05:13:56,600
PARTICIPANTS OR EXTRACTED FROM 

8313
05:13:56,600 --> 05:13:59,080
MEDICAL RECORDS HAS BEEN THE 

8314
05:13:59,080 --> 05:14:00,200
VARIABLE AND SEX AND GENDER 

8315
05:14:00,200 --> 05:14:02,720
SHOULD BE COLLECTED AND STUDIED 

8316
05:14:02,720 --> 05:14:03,560
APPROPRIATELY.

8317
05:14:03,560 --> 05:14:05,400
AND PRACTICES EXIST TO MEASURE 

8318
05:14:05,400 --> 05:14:07,360
GENDER PHENOMENON IN HEALTH 

8319
05:14:07,360 --> 05:14:08,200
RESEARCH AND ADDITIONAL RESEARCH

8320
05:14:08,200 --> 05:14:09,720
TO VALIDATE INSTRUMENTS IN THE 

8321
05:14:09,720 --> 05:14:11,200
COLLECTION OF INFORMATION ABOUT 

8322
05:14:11,200 --> 05:14:13,320
GENDER IS NEEDED.

8323
05:14:13,320 --> 05:14:14,080
EVOLVING SOCIAL NORMS HAVE 

8324
05:14:14,080 --> 05:14:15,720
SHIFTED DEFINITIONS AND 

8325
05:14:15,720 --> 05:14:18,600
UNDERSTANDINGS OF SEX AND GENDER

8326
05:14:18,600 --> 05:14:21,040
AND FEW TOOLS TO MEASURE AND 

8327
05:14:21,040 --> 05:14:22,080
GENDER HAVE BEEN AVAILABLE AND 

8328
05:14:22,080 --> 05:14:22,520
VALIDATED.

8329
05:14:22,520 --> 05:14:24,800
IN THIS CONTEXT, NIH 

8330
05:14:24,800 --> 05:14:26,000
COMMISSIONED THE NATIONAL 

8331
05:14:26,000 --> 05:14:28,520
ACADEMIES OF SCIENCES, 

8332
05:14:28,520 --> 05:14:30,560
ENGINEERING AND MEDICINE TO 

8333
05:14:30,560 --> 05:14:33,600
CONVENE A PANEL OF EXPERTS TO 

8334
05:14:33,600 --> 05:14:35,720
REVIEW THE MEASUREMENT OF SEX, 

8335
05:14:35,720 --> 05:14:38,160
GENDER IDENTITY AND SEXUAL 

8336
05:14:38,160 --> 05:14:39,600
ORIENTATION TO MAKE 

8337
05:14:39,600 --> 05:14:40,400
RECOMMENDATIONS FOR SPECIFIC 

8338
05:14:40,400 --> 05:14:42,520
MEASURES AND TO PROVIDE GUIDANCE

8339
05:14:42,520 --> 05:14:43,320
FOR THEIR USE.

8340
05:14:43,320 --> 05:14:45,320
THIS EFFORT WAS LED BY THE 

8341
05:14:45,320 --> 05:14:46,800
SEXUAL AND GENDER MINORITY 

8342
05:14:46,800 --> 05:14:49,240
RESEARCH OFFICE AND SUPPORTED BY

8343
05:14:49,240 --> 05:14:52,600
18 ADDITIONAL INSTITUTE CENTERS 

8344
05:14:52,600 --> 05:14:57,680
AND OFFICES INCLUDING THE ORWH.

8345
05:14:57,680 --> 05:15:01,280
ACCURATE DEFINITIONS AN 

8346
05:15:01,280 --> 05:15:02,960
APPROPRIATE  TERMINOLOGY ARE 

8347
05:15:02,960 --> 05:15:08,920
ESSENTIAL TO RESEARCH AND THE 

8348
05:15:08,920 --> 05:15:10,560
TWO-STEPS IS CONSIDERED BEST.

8349
05:15:10,560 --> 05:15:12,440
STEP ONES ASKED ABOUT CURRENT 

8350
05:15:12,440 --> 05:15:13,880
GENDER IDENTITY AND INCLUDES A 

8351
05:15:13,880 --> 05:15:16,600
VARIETY OF OPTIONS TO CHOOSE 

8352
05:15:16,600 --> 05:15:18,360
FROM AND STEP TWO ASKS ABOUT SEX

8353
05:15:18,360 --> 05:15:19,520
ASSIGNED AT BIRTH.

8354
05:15:19,520 --> 05:15:22,000
THIS IS WIDELY UTILIZED ACROSS 

8355
05:15:22,000 --> 05:15:24,920
NIH AND THE EXTRAMURAL 

8356
05:15:24,920 --> 05:15:25,560
COMMUNITY.

8357
05:15:25,560 --> 05:15:28,600
FOR EXAMPLE, NIAID DEVELOPED 

8358
05:15:28,600 --> 05:15:30,680
GUIDANCE FOR THEIR HIV CLINICAL 

8359
05:15:30,680 --> 05:15:32,040
TRIALS NETWORK TO HAVE 

8360
05:15:32,040 --> 05:15:33,480
RECOMMENDED MEASURES AND THE ALL

8361
05:15:33,480 --> 05:15:35,200
OF US RESEARCH PROGRAM UTILIZE 

8362
05:15:35,200 --> 05:15:40,400
THE TWO-STEP METHOD.

8363
05:15:40,400 --> 05:15:42,960
THE REPORT INCLUDED RECOMMENDED 

8364
05:15:42,960 --> 05:15:44,120
MEASURES FOR SEX ASSIGNED AT 

8365
05:15:44,120 --> 05:15:46,160
BIRTH AND CURRENT GENDER 

8366
05:15:46,160 --> 05:15:53,480
IDENTIFY SHOWN HERE.

8367
05:15:53,480 --> 05:15:56,320
WHILE THE NAS EM REPORT SAYS IT 

8368
05:15:56,320 --> 05:15:59,560
USES SEX TERMS TO CAPTURE 

8369
05:15:59,560 --> 05:16:02,760
IDENTITY THERE'S A LACK OF DATA 

8370
05:16:02,760 --> 05:16:03,720
USING TERMINOLOGY TO COLLECT 

8371
05:16:03,720 --> 05:16:05,040
CURRENT GENDER IDENTITY.

8372
05:16:05,040 --> 05:16:07,160
THIS HAS BEEN ADDED BUT THE 

8373
05:16:07,160 --> 05:16:09,120
REPORT DOES INDICATE IN THE 

8374
05:16:09,120 --> 05:16:11,640
ABSENCE OF OTHER EVIDENCE THE 

8375
05:16:11,640 --> 05:16:13,320
PANEL'S RECOMMENDATION OF 

8376
05:16:13,320 --> 05:16:14,120
FEMALE/MALE TERMINOLOGY FOR 

8377
05:16:14,120 --> 05:16:18,160
CURRENT GENDER IS IN KEEPING 

8378
05:16:18,160 --> 05:16:20,600
WITH OPENINGS USING THE CURRENT 

8379
05:16:20,600 --> 05:16:30,800
MEASURES.

8380
05:16:33,080 --> 05:16:35,160
THEY USED EXPLICIT TEST OF 

8381
05:16:35,160 --> 05:16:38,040
GENDER TERMINOLOGY OR GENDER 

8382
05:16:38,040 --> 05:16:40,680
IDENTITY RESPONSES IN THE NASEM 

8383
05:16:40,680 --> 05:16:42,360
REPORT.

8384
05:16:42,360 --> 05:16:45,720
STRATEGIC GOAL TWO OF THE 2019 

8385
05:16:45,720 --> 05:16:47,640
THROUGH 2023 TRANS-NIH STRATEGIC

8386
05:16:47,640 --> 05:16:49,120
PLAN FOR WOMEN'S HEALTH RESEARCH

8387
05:16:49,120 --> 05:16:51,200
IS TO DEVELOP METHODS AND 

8388
05:16:51,200 --> 05:16:52,760
LEVERAGE DATA SOURCES TO 

8389
05:16:52,760 --> 05:16:54,760
CONSIDER SEX AND GENDER 

8390
05:16:54,760 --> 05:16:56,680
INFLUENCES THAT ENHANCE RESEARCH

8391
05:16:56,680 --> 05:16:59,000
FOR THE HEALTH OF WOMEN, 

8392
05:16:59,000 --> 05:17:01,240
OBJECTIVE 2.2 IS TO DEVELOP AND 

8393
05:17:01,240 --> 05:17:02,800
ADAPT RELIABLE AND VALID 

8394
05:17:02,800 --> 05:17:04,560
MEASURES RELEVANT TO THE HEALTH 

8395
05:17:04,560 --> 05:17:07,640
OF WOMEN.

8396
05:17:07,640 --> 05:17:10,880
IN ALIGNMENT WITH OBJECTIVE 2.2 

8397
05:17:10,880 --> 05:17:14,240
OF THE 2019 THROUGH 2023 

8398
05:17:14,240 --> 05:17:15,320
STRATEGIC PLAN, TODAY WE PRESENT

8399
05:17:15,320 --> 05:17:18,760
FOR CLEARANCE A CONCEPT ON 

8400
05:17:18,760 --> 05:17:24,600
GENDER AND MEASUREMENT WITH 

8401
05:17:24,600 --> 05:17:27,600
TESTING GENDER TERMINOLOGY, 

8402
05:17:27,600 --> 05:17:31,880
WOMEN, MAN, NON BINARY AND 

8403
05:17:31,880 --> 05:17:36,600
CAPTURE SEX ASSIGNED AT BIRTH 

8404
05:17:36,600 --> 05:17:38,640
AND GENDER IDENTITY.

8405
05:17:38,640 --> 05:17:40,640
AND CENTERS AND OFFICES HAVE 

8406
05:17:40,640 --> 05:17:42,080
EXPRESSED INTEREST IN THE 

8407
05:17:42,080 --> 05:17:44,040
CONCEPT INCLUDING THE SEXUAL AND

8408
05:17:44,040 --> 05:17:47,000
GENDER MINORITY RESEARCH OFFICE 

8409
05:17:47,000 --> 05:17:48,600
AND THE NATIONAL LIBRARY OF 

8410
05:17:48,600 --> 05:17:49,600
MEDICINE AND THE NATIONAL 

8411
05:17:49,600 --> 05:17:54,400
INSTITUTE OF AGING, THE EUNICE 

8412
05:17:54,400 --> 05:17:57,320
KENNEDY SHRIVER HEALTH AND HUMAN

8413
05:17:57,320 --> 05:17:58,360
DEVELOP.

8414
05:17:58,360 --> 05:18:03,160
AND OFFICE OF HUMAN AND 

8415
05:18:03,160 --> 05:18:04,600
BEHAVIORAL SCIENCES RESEARCH.

8416
05:18:04,600 --> 05:18:06,920
WE'RE EXCITED TO SHARE AN 

8417
05:18:06,920 --> 05:18:08,440
OPPORTUNITY FOR ADDITIONAL 

8418
05:18:08,440 --> 05:18:09,440
DIALOGUE WHICH WILL TAKE PLACE 

8419
05:18:09,440 --> 05:18:11,800
NEXT WEDNESDAY AND DR. CLAYTON 

8420
05:18:11,800 --> 05:18:12,600
MENTIONED EARLIER THE SCIENTIFIC

8421
05:18:12,600 --> 05:18:15,760
WORKSHOP TITLED GENDER AND 

8422
05:18:15,760 --> 05:18:18,040
HEALTH IMPACT STRUCTURAL GENDER 

8423
05:18:18,040 --> 05:18:21,560
NORMS AND POWER DYNAMICS AND 

8424
05:18:21,560 --> 05:18:22,720
INEQUITIES FOLLOWING THE OPEN 

8425
05:18:22,720 --> 05:18:24,160
PLENARIES IN THE MORNING FROM 

8426
05:18:24,160 --> 05:18:26,520
THE SPEAKERS THE AFTERNOON WILL 

8427
05:18:26,520 --> 05:18:28,680
FEATURE SESSIONS INCLUDING ONE 

8428
05:18:28,680 --> 05:18:30,560
FOCUSSED ENTIRELY ON ISSUES OF 

8429
05:18:30,560 --> 05:18:31,960
MEASUREMENT AND METHODS.

8430
05:18:31,960 --> 05:18:39,200
THAT WILL FEATURE PRESENTATIONS.

8431
05:18:39,200 --> 05:18:42,960
AND WE INVITE YOU TO VIEW THAT 

8432
05:18:42,960 --> 05:18:44,600
EVENT VIA VIDEOCAST IF YOU HAVE 

8433
05:18:44,600 --> 05:18:48,040
NOT ALREADY REGISTERED.

8434
05:18:48,040 --> 05:18:50,480
AND WITH THAT, I AM HAPPY TO 

8435
05:18:50,480 --> 05:18:51,920
ANSWER QUESTIONS AND THANK YOU 

8436
05:18:51,920 --> 05:19:02,280
FOR YOUR ATTENTION.

8437
05:19:23,280 --> 05:19:24,880
>>WE DON'T COLLECT DATA
WITH 

8438
05:19:24,880 --> 05:19:26,280
RACIAL AND SOME ETHNIC 

8439
05:19:26,280 --> 05:19:26,680
MINORITIES.

8440
05:19:26,680 --> 05:19:29,160
WE DON'T COLLECT DATA ON SEXUAL 

8441
05:19:29,160 --> 05:19:29,480
MINORITIES.

8442
05:19:29,480 --> 05:19:32,600
IT'S BEEN TREATED SOMEWHAT LIKE 

8443
05:19:32,600 --> 05:19:34,120
A TABOO TOPIC.

8444
05:19:34,120 --> 05:19:37,440
IT WOULD BE BETTER IF WE WERE 

8445
05:19:37,440 --> 05:19:39,160
ABLE TO COLLECT DATA WITHOUT 

8446
05:19:39,160 --> 05:19:43,200
BEING FEARFUL BUT HOW CAN WE 

8447
05:19:43,200 --> 05:19:43,800
ADEQUATELY STUDY THESE THINGS 

8448
05:19:43,800 --> 05:19:54,240
WITHOUT COLLECTING DATA?

8449
05:19:58,280 --> 05:20:00,600
IT'S AN IMPORTANT QUESTION AND 

8450
05:20:00,600 --> 05:20:03,400
SEX ASSIGNED AT BIRTH PER GENDER

8451
05:20:03,400 --> 05:20:06,840
IDENTITY DISTINCT FROM SEXUAL 

8452
05:20:06,840 --> 05:20:10,240
ORIENTATION WHICH AFTER 

8453
05:20:10,240 --> 05:20:13,960
SOMEBODY'S GENDERED EXPOSURE AND

8454
05:20:13,960 --> 05:20:16,560
SOMEONE WHO IS A WOMAN MAY OR 

8455
05:20:16,560 --> 05:20:18,880
MAY NOT HAVE BIOLOGICAL 

8456
05:20:18,880 --> 05:20:20,600
ATTRIBUTES THAT WOULD BE 

8457
05:20:20,600 --> 05:20:21,720
ASSIGNED WITH FEMALE SEX AND 

8458
05:20:21,720 --> 05:20:23,960
BOTH VARIABLES ARE RELEVANT WITH

8459
05:20:23,960 --> 05:20:25,440
A HOST OF OTHER DEMOGRAPHIC 

8460
05:20:25,440 --> 05:20:25,720
VARIABLES.

8461
05:20:25,720 --> 05:20:29,160
IT'S IMPORTANT TO USE PRECISE 

8462
05:20:29,160 --> 05:20:32,960
AND ACCURATE TERMINOLOGY 

8463
05:20:32,960 --> 05:20:39,320
THROUGHOUT.

8464
05:20:39,320 --> 05:20:43,160
>>OUR OFFICE IN
POUGHKEEPSIE IS

8465
05:20:43,160 --> 05:20:45,200
DIVING INTO THE DOMAIN OF 

8466
05:20:45,200 --> 05:20:46,320
ORIENTATION AND ONE THAT IS 

8467
05:20:46,320 --> 05:20:48,800
IMPORTANT TO HEALTH AND TRYING 

8468
05:20:48,800 --> 05:20:49,960
TO THINK THROUGH STRATEGIES FOR 

8469
05:20:49,960 --> 05:20:52,600
AS YOU SAID INTEGRATING IT IN A 

8470
05:20:52,600 --> 05:20:58,800
WAY THAT IS MEANINGFUL AND 

8471
05:20:58,800 --> 05:21:00,560
CLINICALLY RELEVANT AND ALLOWS 

8472
05:21:00,560 --> 05:21:01,960
PEOPLE TO FEEL COMFORTABLE 

8473
05:21:01,960 --> 05:21:03,360
REPORTING THAT INFORMATION IN 

8474
05:21:03,360 --> 05:21:04,600
THE CONTEXT OF IT BEING 

8475
05:21:04,600 --> 05:21:06,520
IMPORTANT FOR THEIR HEALTH AND 

8476
05:21:06,520 --> 05:21:09,960
SO SGMRO, WE WORKED CLOSELY WITH

8477
05:21:09,960 --> 05:21:12,600
THEM AND WE HAVE SUPPORTED SOME 

8478
05:21:12,600 --> 05:21:13,840
OF THEIR EFFORTS AS WELL AS WE 

8479
05:21:13,840 --> 05:21:15,760
MOVE THROUGH THE EVOLVING 

8480
05:21:15,760 --> 05:21:20,080
CONCEPTS ALWAYS IN THE SERVICE 

8481
05:21:20,080 --> 05:21:24,600
OF IMPROVING THE HEALTH OF 

8482
05:21:24,600 --> 05:21:28,040
EVERYONE.

8483
05:21:28,040 --> 05:21:29,440
>>QUESTIONS?

8484
05:21:29,440 --> 05:21:30,840
DR. BARR.

8485
05:21:30,840 --> 05:21:38,080
DR. TEMPLETON.

8486
05:21:38,080 --> 05:21:39,600
>>A WONDERFUL
PRESENTATION.

8487
05:21:39,600 --> 05:21:41,320
WITH THE PREVAILING POLITICAL 

8488
05:21:41,320 --> 05:21:42,920
WINDS IN THE COUNTRY WHERE SOME 

8489
05:21:42,920 --> 05:21:46,240
STATES ARE ALLOWING ONLY LOOKING

8490
05:21:46,240 --> 05:21:48,200
AT BIOLOGIC SEX INDICATING 

8491
05:21:48,200 --> 05:21:49,800
THAT'S ALL THAT EXISTS AND 

8492
05:21:49,800 --> 05:21:51,240
IGNORING THE FACT THAT GENDER 

8493
05:21:51,240 --> 05:21:51,840
MAY BE DIFFERENT.

8494
05:21:51,840 --> 05:21:54,040
WHAT CAN WE DO OR ARE THERE 

8495
05:21:54,040 --> 05:21:56,240
PLANS IN LOOKING AT EDUCATION OF

8496
05:21:56,240 --> 05:22:00,320
POLICY MAKERS TO LET THEM KNOW 

8497
05:22:00,320 --> 05:22:03,120
THAT ACTUALLY GENDER IS A THING 

8498
05:22:03,120 --> 05:22:04,800
AND NOT THE SAME AS SEX AND MAY 

8499
05:22:04,800 --> 05:22:06,960
CORRELATE AND MAY NOT BUT I 

8500
05:22:06,960 --> 05:22:09,280
WORRY ESPECIALLY WITH PEOPLE 

8501
05:22:09,280 --> 05:22:11,080
WORKING IN STATE-SPONSORED 

8502
05:22:11,080 --> 05:22:14,960
ACADEMIC INSTITUTIONS SOME MAY 

8503
05:22:14,960 --> 05:22:18,320
BE HANDICAPPED IN NOT BEING ABLE

8504
05:22:18,320 --> 05:22:19,320
TO FULLY EXPLORE THIS IMPORTANT 

8505
05:22:19,320 --> 05:22:21,080
AREA OF SCIENCE BECAUSE OF THE 

8506
05:22:21,080 --> 05:22:21,720
POLITICAL INFLUENCES AT THE SATE

8507
05:22:21,720 --> 05:22:24,600
LEVEL.

8508
05:22:24,600 --> 05:22:27,760
>>DR. CLAYTON, WOULD I
LIKE TO 

8509
05:22:27,760 --> 05:22:29,480
RESPOND TO THAT?

8510
05:22:29,480 --> 05:22:31,480
>>DR. TEMPLETON, YOUR 

8511
05:22:31,480 --> 05:22:32,600
HIGHLIGHTING VERY IMPORTANT 

8512
05:22:32,600 --> 05:22:37,280
ISSUES THAT AFFECT US IN OUR 

8513
05:22:37,280 --> 05:22:37,800
TODAY.

8514
05:22:37,800 --> 05:22:41,240
OUR PART IS TO PROVIDE 

8515
05:22:41,240 --> 05:22:42,720
INFORMATION TO SUPPORT DATA, 

8516
05:22:42,720 --> 05:22:44,160
GENERATION OF EVIDENCE AND THAT 

8517
05:22:44,160 --> 05:22:45,720
NEEDS TO ALWAYS BE DONE IN THE 

8518
05:22:45,720 --> 05:22:47,400
MOST RIGOROUS PAY POSSIBLE.

8519
05:22:47,400 --> 05:22:50,560
AS WE LEARN MORE ABOUT THE 

8520
05:22:50,560 --> 05:22:52,520
CONCEPTS, WE EXPAND AND THINK 

8521
05:22:52,520 --> 05:22:56,080
ABOUT THEM AS PER SCIENCE.

8522
05:22:56,080 --> 05:23:00,560
WE HAVE INVESTED IN A WIDE 

8523
05:23:00,560 --> 05:23:03,000
VARIETY OF INTEREDUCATIONAL TOOL

8524
05:23:03,000 --> 05:23:04,600
TO HAVE THEM FREELY AVAILABLE TO

8525
05:23:04,600 --> 05:23:08,640
THE PUBLIC AND DIRECTED TOWARDS 

8526
05:23:08,640 --> 05:23:10,480
VARIOUS AUDIENCES AT DIFFERENT 

8527
05:23:10,480 --> 05:23:12,360
LEVELS AND WE HAVE AN 

8528
05:23:12,360 --> 05:23:13,640
INTRODUCTORY COURSE NOW AND EVEN

8529
05:23:13,640 --> 05:23:14,640
TO THE TRAIN THE TRAINER 

8530
05:23:14,640 --> 05:23:15,040
MATERIALS.

8531
05:23:15,040 --> 05:23:21,680
AND DR. BARR IS A WONDERFUL 

8532
05:23:21,680 --> 05:23:24,600
LEADER IN THE INTERPROFESSIONAL 

8533
05:23:24,600 --> 05:23:25,760
EDUCATIONAL EFFORTS AS WELL AS 

8534
05:23:25,760 --> 05:23:27,360
THE CONTENT WE DISSEMINATE 

8535
05:23:27,360 --> 05:23:27,640
PUBLICLY.

8536
05:23:27,640 --> 05:23:30,640
WE SEEK TO HAVE THAT ALWAYS BE 

8537
05:23:30,640 --> 05:23:32,600
DATA DRIVEN AND EVIDENCE 

8538
05:23:32,600 --> 05:23:32,840
DERIVED.

8539
05:23:32,840 --> 05:23:35,600
AGAIN IN THE SPIRIT OF INCLUDING

8540
05:23:35,600 --> 05:23:39,160
THE HEALTH OF EVERYONE.

8541
05:23:39,160 --> 05:23:40,400
THE OFFICE HAS A SPECIFIC FOCUS 

8542
05:23:40,400 --> 05:23:44,200
ON THE HEALTH OF WOMEN AS YOU 

8543
05:23:44,200 --> 05:23:47,240
KNOW AND WE DO PROVIDE 

8544
05:23:47,240 --> 05:23:48,880
INFORMATION THROUGH MEDIA 

8545
05:23:48,880 --> 05:23:52,960
INTERVIEWS, THROUGH WEB CONTENT,

8546
05:23:52,960 --> 05:23:54,880
THROUGH REPORTING PUBLICATIONS.

8547
05:23:54,880 --> 05:23:59,120
WE PUSH OUT A LOT OF CONTENT TO 

8548
05:23:59,120 --> 05:24:00,640
MAKE IT AVAILABLE AND RECOGNIZE 

8549
05:24:00,640 --> 05:24:03,320
IT'S A COMPLEX SPACE WITH MANY 

8550
05:24:03,320 --> 05:24:05,040
STAKEHOLDERS AND MANY OBJECTIVES

8551
05:24:05,040 --> 05:24:07,040
AND AGENDAS OF DIFFERENT 

8552
05:24:07,040 --> 05:24:07,400
STAKEHOLDERS.

8553
05:24:07,400 --> 05:24:08,600
SO WE ARE COMMITTED TO 

8554
05:24:08,600 --> 05:24:09,760
GENERATING THAT EVIDENCE AND 

8555
05:24:09,760 --> 05:24:12,320
MAKING SURE THAT EVIDENCE IS 

8556
05:24:12,320 --> 05:24:14,320
AVAILABLE AND WITH THIS CONCEPT 

8557
05:24:14,320 --> 05:24:16,600
DR. BARR JUST PRESENTED TO YOU, 

8558
05:24:16,600 --> 05:24:18,880
WE'RE HOPING TO REFINE SOME OF 

8559
05:24:18,880 --> 05:24:20,920
THE DIFFICULTIES OF THOSE AROUND

8560
05:24:20,920 --> 05:24:23,200
GENDER AND IMPROVE THE METHODS 

8561
05:24:23,200 --> 05:24:25,400
AND MEASUREMENTS, MAYBE WE CAN 

8562
05:24:25,400 --> 05:24:26,600
MAKE SOME STEPS FORWARD TOGETHER

8563
05:24:26,600 --> 05:24:28,600
AS A SOCIETY TO BE ABLE TO 

8564
05:24:28,600 --> 05:24:31,200
ADDRESS THIS IMPORTANT ASPECT OF

8565
05:24:31,200 --> 05:24:31,480
HEALTH.

8566
05:24:31,480 --> 05:24:34,720
SO I KNOW THAT MAY NOT BE 

8567
05:24:34,720 --> 05:24:35,960
ANSWERING EVERYTHING YOU ASKED, 

8568
05:24:35,960 --> 05:24:46,520
BUT WE'RE TRYING TO DO OUR PART.

8569
05:24:52,520 --> 05:25:00,080
>>I WANT TO FRAME THIS
AND 

8570
05:25:00,080 --> 05:25:04,200
THERE'S A CONSENSUS STUDY I'M 

8571
05:25:04,200 --> 05:25:06,360
PART OF DRIVING RACIAL AND 

8572
05:25:06,360 --> 05:25:08,600
ETHNIC HEALTH DISPARITIES AND 

8573
05:25:08,600 --> 05:25:12,840
PART OF WHAT I ALWAYS HEAR IN 

8574
05:25:12,840 --> 05:25:15,800
TERMS OF RESEARCH AND IMPACTS OF

8575
05:25:15,800 --> 05:25:17,800
WOMEN'S HEALTH AND YOUR FIRST 

8576
05:25:17,800 --> 05:25:20,040
SLIDE, DR. BARR, THAT I LOVE.

8577
05:25:20,040 --> 05:25:24,600
WAY WANT TO MAKE SURE WE DO IS 

8578
05:25:24,600 --> 05:25:27,720
WHEN WE THINK ABOUT POLICY AND 

8579
05:25:27,720 --> 05:25:29,040
RESEARCH AND HOW THOSE 

8580
05:25:29,040 --> 05:25:31,320
INTERTWINE AND IMPACT HEALTH OR 

8581
05:25:31,320 --> 05:25:34,840
DETRACT FROM HEALTH, WHAT DO WE 

8582
05:25:34,840 --> 05:25:38,160
HAVE TO DE-IMPLEMENT BECAUSE IN 

8583
05:25:38,160 --> 05:25:39,800
THE WORLD OF IMPLEMENTATION 

8584
05:25:39,800 --> 05:25:44,880
SCIENCE AND THIS RESEARCH THAT 

8585
05:25:44,880 --> 05:25:52,560
GOES ON WHETHER IT'S A TRIAL 

8586
05:25:52,560 --> 05:25:54,320
THAT GOES INTO CLINICAL PRACTICE

8587
05:25:54,320 --> 05:25:55,400
AND WHEN NEW RESEARCH COMES OUT 

8588
05:25:55,400 --> 05:26:01,080
WE FORGET WE HAVE TO ACTIVELY 

8589
05:26:01,080 --> 05:26:03,240
DE-IMPLEMENT THE STUFF WE'VE 

8590
05:26:03,240 --> 05:26:03,920
BEEN DOING AND THERE'S LESS 

8591
05:26:03,920 --> 05:26:06,720
RESEARCH AND STUDY HOW TO 

8592
05:26:06,720 --> 05:26:07,440
DE-IMPLEMENT SOMETHING WHILE 

8593
05:26:07,440 --> 05:26:09,400
YOU'RE TRYING TO IMPLEMENT A NEW

8594
05:26:09,400 --> 05:26:09,800
THING.

8595
05:26:09,800 --> 05:26:13,720
THIS IS REALLY IMPORTANT FOR HOW

8596
05:26:13,720 --> 05:26:17,680
GENDER AND RACE AND ALL THOSE 

8597
05:26:17,680 --> 05:26:19,600
OTHER INTERSECTIONAL IDENTITIES 

8598
05:26:19,600 --> 05:26:21,840
PLAY OUT IN THIS SPACE.

8599
05:26:21,840 --> 05:26:24,520
SO DE-IMPLEMENTATION IS AN 

8600
05:26:24,520 --> 05:26:25,160
IMPORTANT PART OF THE RESEARCH 

8601
05:26:25,160 --> 05:26:29,960
TOO.

8602
05:26:29,960 --> 05:26:32,400
>>IF I CAN JUST RESPOND
BRIEFLY

8603
05:26:32,400 --> 05:26:34,440
I KNOW WE'RE NEAR TIME.

8604
05:26:34,440 --> 05:26:36,480
THE DIVISION OF AIDS OVER AT 

8605
05:26:36,480 --> 05:26:38,520
NIAID HAS DONE A LOT OF 

8606
05:26:38,520 --> 05:26:40,560
FOUNDATIONAL WORK THROUGH THEIR 

8607
05:26:40,560 --> 05:26:42,000
HIV NETWORKS AND SOME OF THEIR 

8608
05:26:42,000 --> 05:26:43,800
GUIDANCE AROUND IMPLEMENTING A 

8609
05:26:43,800 --> 05:26:45,520
TWO-STEP METHOD OF DATA 

8610
05:26:45,520 --> 05:26:47,120
COLLECTION THEY ALSO REALLY 

8611
05:26:47,120 --> 05:26:48,320
STRESSED THE IMPORTANCE OF STAFF

8612
05:26:48,320 --> 05:26:52,560
TRAINING AND RECOGNIZING THAT 

8613
05:26:52,560 --> 05:26:54,880
NOT ALL STAFF AND THERE'S A 

8614
05:26:54,880 --> 05:26:55,640
SHARED BASELINE LEVEL OF 

8615
05:26:55,640 --> 05:26:57,720
UNDERSTANDING OF THE LANGUAGE 

8616
05:26:57,720 --> 05:26:59,400
AND THE ISSUES.

8617
05:26:59,400 --> 05:27:02,400
I THINK THERE ARE POCKETS AND 

8618
05:27:02,400 --> 05:27:04,320
EFFORTS EXISTING AND I FULLY 

8619
05:27:04,320 --> 05:27:08,600
AGREE IT'S IMPORTANT TO AMPLIFY 

8620
05:27:08,600 --> 05:27:18,720
THOSE.

8621
05:27:21,680 --> 05:27:23,520
>>ANYONE ELSE?

8622
05:27:23,520 --> 05:27:24,160
ANY QUESTIONS?

8623
05:27:24,160 --> 05:27:24,880
THANK YOU.

8624
05:27:24,880 --> 05:27:28,400
HAVE YOU FOR YOUR ENGAGEMENT.

8625
05:27:28,400 --> 05:27:34,720
I'D LIKE TO MOVE ON TO THE NEXT 

8626
05:27:34,720 --> 05:27:35,920
STEP WITH THIS AND TO APPROVE 

8627
05:27:35,920 --> 05:27:39,120
THE GENDER AND MEASUREMENT 

8628
05:27:39,120 --> 05:27:39,560
CONCEPT CLEARANCE.

8629
05:27:39,560 --> 05:27:43,360
IS THERE A MOTION ON THE TABLE 

8630
05:27:43,360 --> 05:27:48,600
TO APPROVE THE GENDER AND MER --

8631
05:27:48,600 --> 05:27:49,560
MEASUREMENT CONCEPT CLEARANCE.

8632
05:27:49,560 --> 05:27:59,960
>>I'LL MAKE THE MOTION.

8633
05:28:08,000 --> 05:28:10,440
PLEASE ENTER YOUR RESPONSES NOW 

8634
05:28:10,440 --> 05:28:20,840
AND YOU HAVE 30 SECONDS.

8635
05:28:44,960 --> 05:28:45,720
>>THANK YOU.

8636
05:28:45,720 --> 05:28:47,640
WE HAVE 14 IN FAVOR AND ONE 

8637
05:28:47,640 --> 05:28:47,880
OPPOSED.

8638
05:28:47,880 --> 05:28:48,720
>>THANK YOU VERY MUCH.

8639
05:28:48,720 --> 05:28:51,640
THE GENDER AND MEASUREMENT 

8640
05:28:51,640 --> 05:28:54,200
CONCEPT CLEARANCE HAS BEEN 

8641
05:28:54,200 --> 05:28:56,080
ACCEPTED WITH 14 IN FAVOR AND 

8642
05:28:56,080 --> 05:28:56,480
ONE OPPOSED.

8643
05:28:56,480 --> 05:29:01,560
THANK YOU, DR. BARR.

8644
05:29:01,560 --> 05:29:04,360
AND PLEASE DO STAY ON BECAUSE 

8645
05:29:04,360 --> 05:29:07,560
I'M GOING TURN IT TO YOU TO 

8646
05:29:07,560 --> 05:29:10,800
INTRODUCE OUR NEXT PRESENTER.

8647
05:29:10,800 --> 05:29:11,600
>>THANK YOU.

8648
05:29:11,600 --> 05:29:13,200
I'M HAPPY TO STAY WITH YOU FOR 

8649
05:29:13,200 --> 05:29:16,240
THE NEXT PRESENTATION AND TO BE 

8650
05:29:16,240 --> 05:29:20,120
JOINED BY EMILY GERRICKE AND 

8651
05:29:20,120 --> 05:29:21,720
WILL YOU BE SHARING YOUR SCREEN?

8652
05:29:21,720 --> 05:29:31,880
PERFECT.

8653
05:29:34,000 --> 05:29:35,400
WE CAN SEE YOUR SCREEN BUT 

8654
05:29:35,400 --> 05:29:39,240
YOU'RE NOT IN PRESENTER MODE.

8655
05:29:39,240 --> 05:29:39,760
PERFECT.

8656
05:29:39,760 --> 05:29:43,000
AS MENTIONED SHE WILL PROVIDE AN

8657
05:29:43,000 --> 05:29:45,720
OVERVIEW OF OUR E LEARNING 

8658
05:29:45,720 --> 05:29:48,600
COURSES AND WILL GIVE A LIVE 

8659
05:29:48,600 --> 05:29:51,280
DEMONSTRATION.

8660
05:29:51,280 --> 05:29:56,600
THE AUDIENCE IS VERY FAMILIAR 

8661
05:29:56,600 --> 05:29:58,120
WITH THE NEED FOR THE QUOTE 

8662
05:29:58,120 --> 05:30:00,040
SHOWN HERE UNDER SCORES THE 

8663
05:30:00,040 --> 05:30:02,680
SIGNIFICANT GAPS THAT EXIST IN 

8664
05:30:02,680 --> 05:30:06,120
CURRENT TRAINING IN AUDIT 

8665
05:30:06,120 --> 05:30:08,600
MEDICAL SCHOOLS CURRICULA FOUND 

8666
05:30:08,600 --> 05:30:10,440
LESS THAN ONE-QUARTER OF 

8667
05:30:10,440 --> 05:30:12,560
TRAINING RELATED TO SEX AND 

8668
05:30:12,560 --> 05:30:13,760
GENDER.

8669
05:30:13,760 --> 05:30:16,400
AND JUST 8% INCLUDE IN DEPTH 

8670
05:30:16,400 --> 05:30:20,600
DISCUSSION OF THE IMPORTANT 

8671
05:30:20,600 --> 05:30:21,680
CONCEPTS.

8672
05:30:21,680 --> 05:30:23,240
DESPITE THE RELEVANCE OF BOTH 

8673
05:30:23,240 --> 05:30:25,840
SEX AND GENDER TO HEALTH, THE 

8674
05:30:25,840 --> 05:30:30,000
CONCEPTS ARE PERSISTENTLY UNDER 

8675
05:30:30,000 --> 05:30:30,760
EXPLORED IN HEALTH RELATED 

8676
05:30:30,760 --> 05:30:32,600
TRAINING MAKING IT DIFFICULT TO 

8677
05:30:32,600 --> 05:30:35,280
REACH A TARGET STATE WHERE THIS 

8678
05:30:35,280 --> 05:30:37,080
POPULATION IS INTEGRATED INTO 

8679
05:30:37,080 --> 05:30:40,440
RESEARCH AND IT'S CRITICAL IN 

8680
05:30:40,440 --> 05:30:44,280
BRINGING THE TARGET STATE AND 

8681
05:30:44,280 --> 05:30:47,000
THE OFFICE HAS SUPPORTED A 

8682
05:30:47,000 --> 05:30:48,560
EDUCATION TRAINING PROGRAM TO 

8683
05:30:48,560 --> 05:30:51,120
REACH ALL THAT INTERACTION 

8684
05:30:51,120 --> 05:30:53,400
INCLUDING CLINICIANS, 

8685
05:30:53,400 --> 05:30:55,200
RESEARCHERS, VETERINARIANS, 

8686
05:30:55,200 --> 05:30:56,600
PHARMACISTS, DATA SCIENTISTS, 

8687
05:30:56,600 --> 05:31:00,240
JOURNAL EDITORS AND MORE.

8688
05:31:00,240 --> 05:31:05,480
SO WITH THAT SAID OUR GOALS ARE 

8689
05:31:05,480 --> 05:31:07,600
TO PROVIDE OVERVIEW OF THE 

8690
05:31:07,600 --> 05:31:08,960
COURSE OFFERINGS AS WELL AS THE 

8691
05:31:08,960 --> 05:31:11,280
UNDERSTANDING OF THE KEY 

8692
05:31:11,280 --> 05:31:12,360
AUDIENCES OF THE COURSES 

8693
05:31:12,360 --> 05:31:15,360
FOLLOWED BY A LIVE DEMO.

8694
05:31:15,360 --> 05:31:20,040
JUST SOME HIGH LEVEL METRICS AS 

8695
05:31:20,040 --> 05:31:24,280
OF SEPTEMBER OVER 200,000 

8696
05:31:24,280 --> 05:31:28,600
INDIVIDUALS REGISTERED FOR THE 

8697
05:31:28,600 --> 05:31:30,800
COURSE AND OR THE INTRODUCTORY 

8698
05:31:30,800 --> 05:31:32,560
TRAINING AND OVER 1200 

8699
05:31:32,560 --> 05:31:34,600
INDIVIDUALS ADD THE END OF 

8700
05:31:34,600 --> 05:31:35,520
SEPTEMBER STARTED OR COMPLETE 

8701
05:31:35,520 --> 05:31:38,680
THE MODULE OF BED TO BEDSIDE AND

8702
05:31:38,680 --> 05:31:42,080
750 COMPLETED A MODULE SO 

8703
05:31:42,080 --> 05:31:44,600
THERE'S HIGH INTERESTED AS SHOWN

8704
05:31:44,600 --> 05:31:46,320
BY LEARNERS' REPORTED 

8705
05:31:46,320 --> 05:31:48,440
AFFILIATION IN 56 COUNTRIES.

8706
05:31:48,440 --> 05:31:55,400
A GLOBAL REACH NOR  -- FOR THE 

8707
05:31:55,400 --> 05:31:57,400
PROGRAM AND I'LL TURN IT TO 

8708
05:31:57,400 --> 05:32:00,600
EMILY WHO WILL WALK US THROUGH 

8709
05:32:00,600 --> 05:32:11,040
THE REST OF THE RELATION.

8710
05:32:17,240 --> 05:32:18,240
>>I WON'T SPEND TOO MUCH
TIME 

8711
05:32:18,240 --> 05:32:19,800
ON THIS SLIDE BECAUSE WE HAVE A 

8712
05:32:19,800 --> 05:32:20,880
GREAT RESOURCE.

8713
05:32:20,880 --> 05:32:22,760
OUR COURSE GUIDE PDF IS A 

8714
05:32:22,760 --> 05:32:24,520
DOWNLOADABLE RESOURCE FROM OUR 

8715
05:32:24,520 --> 05:32:27,520
WEBSITE AND I THINK DR. BARR CAN

8716
05:32:27,520 --> 05:32:28,800
PUT THE LINK TO IT IN THE CHAT 

8717
05:32:28,800 --> 05:32:31,320
THAT HAS AN OVERVIEW OF THE 

8718
05:32:31,320 --> 05:32:32,120
COURSE OFFERINGS AND WHAT TO 

8719
05:32:32,120 --> 05:32:34,440
EXPECT FROM EACH COURSE AND THE 

8720
05:32:34,440 --> 05:32:37,760
MODULES AND A BIT ABOUT WHO 

8721
05:32:37,760 --> 05:32:40,640
THEY'RE FOR BUT I'LL GO OVER IN 

8722
05:32:40,640 --> 05:32:42,360
BRIEF, THE BENCH TO BEDSIDE 

8723
05:32:42,360 --> 05:32:43,560
COURSE IS A THOROUGH 

8724
05:32:43,560 --> 05:32:45,520
UNDERSTANDING OF SEX AND GENDER 

8725
05:32:45,520 --> 05:32:46,520
INFLUENCES AND HEALTH AND 

8726
05:32:46,520 --> 05:32:48,440
DISEASE AND AS DR. BARR 

8727
05:32:48,440 --> 05:32:50,160
MENTIONED EARLIER WE'RE TRYING 

8728
05:32:50,160 --> 05:32:51,640
TO REACH ANYONE WHO WOULD 

8729
05:32:51,640 --> 05:32:53,120
INTERACT AND INTERFACE WITH THE 

8730
05:32:53,120 --> 05:32:57,960
HEALTH ECO SYSTEM WITH THIS 

8731
05:32:57,960 --> 05:32:58,240
COURSE.

8732
05:32:58,240 --> 05:32:59,920
AND THERE'S CMEs AVAILABLE FOR 

8733
05:32:59,920 --> 05:33:01,240
THIS AND IT WAS DEVELOPED IN 

8734
05:33:01,240 --> 05:33:06,800
PARTNERSHIP WITH THE FDA.

8735
05:33:06,800 --> 05:33:08,400
THE SUPPLEMENT COURSE IS ABOUT 

8736
05:33:08,400 --> 05:33:10,160
DEMONSTRATING HOW TO CONSIDER 

8737
05:33:10,160 --> 05:33:12,600
SABBs IN ALL STAGES OF MEDICAL 

8738
05:33:12,600 --> 05:33:14,280
RESEARCH TO CLARIFY POLICY AND 

8739
05:33:14,280 --> 05:33:16,280
HOW TO PLY IT AND THE TRAIN THE 

8740
05:33:16,280 --> 05:33:18,680
TRAINER COURSE PROVIDES 

8741
05:33:18,680 --> 05:33:20,600
STRATEGIES AND BEST PRACTICES 

8742
05:33:20,600 --> 05:33:24,080
HOW TO TEACH THE SAB POLICIES 

8743
05:33:24,080 --> 05:33:27,880
AND CONCEPT TO OTHERS AND IT'S A

8744
05:33:27,880 --> 05:33:35,840
GREAT INTRODUCTORY RESOURCE AND 

8745
05:33:35,840 --> 05:33:37,800
BREAKS DOWN SEX AND GENDER AND 

8746
05:33:37,800 --> 05:33:40,600
HOW TO APPLY IT IN CLINICAL CARE

8747
05:33:40,600 --> 05:33:47,120
AND A  RESEARCH AND IT PROVIDED 

8748
05:33:47,120 --> 05:33:50,160
FUNDING FOR THE SABV PRIMARY 

8749
05:33:50,160 --> 05:33:50,480
SUPPLEMENT.

8750
05:33:50,480 --> 05:33:52,600
THIS IS TO NOTE THERE'S A PRE 

8751
05:33:52,600 --> 05:33:55,960
TEST WE ADMINISTER BEFORE YOU 

8752
05:33:55,960 --> 05:33:57,240
CREATE AN ACCOUNT BEFORE THEY'RE

8753
05:33:57,240 --> 05:34:00,400
ABLE TO ACCESS COURSES WHICH 

8754
05:34:00,400 --> 05:34:01,520
ALLOWS US TO ASSESS LEARNING 

8755
05:34:01,520 --> 05:34:02,960
AFTER TAKING THE COURSES.

8756
05:34:02,960 --> 05:34:04,760
YOU WON'T SEE THIS IN THE DEMO 

8757
05:34:04,760 --> 05:34:06,640
BECAUSE I ALREADY LOGGED IN BUT 

8758
05:34:06,640 --> 05:34:07,360
WE WANTED TO FLAG IT SO YOU'RE 

8759
05:34:07,360 --> 05:34:10,960
AWARE.

8760
05:34:10,960 --> 05:34:12,200
THE BENCH TO BEDSIDE COURSE, 

8761
05:34:12,200 --> 05:34:13,800
WHEN WE TALK ABOUT WHO IT'S FOR 

8762
05:34:13,800 --> 05:34:16,480
AS MENTIONED EARLIER ANYONE WHO 

8763
05:34:16,480 --> 05:34:18,760
INTERFACES WITH THE HEALTH ECO 

8764
05:34:18,760 --> 05:34:21,040
SYSTEM FROM CLINICIANS TO HEALTH

8765
05:34:21,040 --> 05:34:23,280
PROFESSIONALS TO POLICY MAKERS 

8766
05:34:23,280 --> 05:34:24,480
AND RESEARCHERS AND STUDENTS 

8767
05:34:24,480 --> 05:34:26,800
FROM AN ADVANCED UNDERGRADUATE 

8768
05:34:26,800 --> 05:34:28,560
LEVEL TO GRADUATE AND 

8769
05:34:28,560 --> 05:34:29,520
PHARMACEUTICAL AND OTHER 

8770
05:34:29,520 --> 05:34:30,400
PROFESSIONAL SCHOOLS.

8771
05:34:30,400 --> 05:34:31,600
AS WELL AS ALL INTERESTED 

8772
05:34:31,600 --> 05:34:32,880
LEARNERS.

8773
05:34:32,880 --> 05:34:39,720
SO THE SIX MODULESS COVER 

8774
05:34:39,720 --> 05:34:40,360
IMMUNO

8775
05:34:40,360 --> 05:34:40,960
IMMUNOLOGY, CARDIOVASCULAR 

8776
05:34:40,960 --> 05:34:44,600
DISEASE, ENDOCRINOLOGY AND 

8777
05:34:44,600 --> 05:34:44,920
MENTAL HEALTH.

8778
05:34:44,920 --> 05:34:46,240
THIS IS PROBABLY THE MOST 

8779
05:34:46,240 --> 05:34:47,960
IMPORTANT SLIDE WE WANTED TO 

8780
05:34:47,960 --> 05:34:51,000
TAKE A MOMENT TO SHOW DURING THE

8781
05:34:51,000 --> 05:34:51,360
DEMONSTRATION.

8782
05:34:51,360 --> 05:34:54,040
THERE MANY WAYS WE THINK OF AND 

8783
05:34:54,040 --> 05:34:55,520
PROBABLY OTHERS WE HAVEN'T 

8784
05:34:55,520 --> 05:34:57,680
THOUGHT OF FOR APPLYING THE 

8785
05:34:57,680 --> 05:34:59,200
BENCH TO BEDSIDE COURSE AS WELL 

8786
05:34:59,200 --> 05:35:03,000
AS OTHER COURSES BUT THIS IS TO 

8787
05:35:03,000 --> 05:35:05,080
SHOW YOU WHAT WE HAD IN MIND IN 

8788
05:35:05,080 --> 05:35:05,840
CREATING THE RESOURCES.

8789
05:35:05,840 --> 05:35:07,520
ONE IS INCORPORATING INTO 

8790
05:35:07,520 --> 05:35:09,200
ACADEMIC COURSES OR 

8791
05:35:09,200 --> 05:35:10,080
INCORPORATING AS TRAINING FOR 

8792
05:35:10,080 --> 05:35:12,560
LAB MEMBERS PROVIDING AN EXTRA 

8793
05:35:12,560 --> 05:35:15,720
CREDIT OPTION FOR STUDENT AND 

8794
05:35:15,720 --> 05:35:18,080
SHARING SCHOOL LIBRARIES AND 

8795
05:35:18,080 --> 05:35:19,360
SHARING WITH PROFESSIONALS AND 

8796
05:35:19,360 --> 05:35:21,280
WHAT THEY CAN LINK TO OR IN 

8797
05:35:21,280 --> 05:35:24,920
PRINT RESOURCES THAT WE HAVE 

8798
05:35:24,920 --> 05:35:27,040
LIKE A COURSE GUIDE TO BE SHARED

8799
05:35:27,040 --> 05:35:29,520
WITH DEPARTMENT FACULTY AND 

8800
05:35:29,520 --> 05:35:30,760
NETWORKS AND WE ALWAYS VALUE 

8801
05:35:30,760 --> 05:35:32,480
ANYONE WHO HAS TAKEN THE COURSE 

8802
05:35:32,480 --> 05:35:33,720
SHARING AND THEIR EXPERIENCES 

8803
05:35:33,720 --> 05:35:34,880
WITH COLLEAGUES AND FRIENDS 

8804
05:35:34,880 --> 05:35:37,520
THROUGH THEIR E-MAIL OR SOCIAL 

8805
05:35:37,520 --> 05:35:39,120
MEDIA PLATFORMS OR IN 

8806
05:35:39,120 --> 05:35:42,520
CONSULTATION WITH COLLEAGUES.

8807
05:35:42,520 --> 05:35:44,040
AND WITH THAT I'LL MOVE TO THE 

8808
05:35:44,040 --> 05:35:46,080
BENCH TO BEDSIDE DEMOS.

8809
05:35:46,080 --> 05:35:48,360
I'M GOING TO ASK ELIZABETH TO 

8810
05:35:48,360 --> 05:35:50,600
CONFIRM FOR ME SHE CAN STILL 

8811
05:35:50,600 --> 05:35:53,200
SEE -- CAN YOU SEE MY BROWSER 

8812
05:35:53,200 --> 05:35:53,400
SCREEN?

8813
05:35:53,400 --> 05:35:54,520
>>YES.

8814
05:35:54,520 --> 05:35:54,800
>>GREAT.

8815
05:35:54,800 --> 05:35:57,720
THIS IS A FEW OF WHAT YOU'D SEE 

8816
05:35:57,720 --> 05:36:00,040
BEFORE YOU LOG INTO THE -- 

8817
05:36:00,040 --> 05:36:01,600
BEFORE YOU CREATE AN ACCOUNT AND

8818
05:36:01,600 --> 05:36:02,640
LOG INTO E-LEARNING.

8819
05:36:02,640 --> 05:36:04,560
YOU CAN FIND IT UNDER THE CAREER

8820
05:36:04,560 --> 05:36:05,720
DEVELOPMENT AND EDUCATION TAB ON

8821
05:36:05,720 --> 05:36:06,640
THE WEBSITE.

8822
05:36:06,640 --> 05:36:10,320
YOU CAN GET TO THE MAIN COURSE 

8823
05:36:10,320 --> 05:36:12,280
COLUMN BY CLICKING E-LEARNING 

8824
05:36:12,280 --> 05:36:13,720
AND THAT WILL TAKE YOU HERE AND 

8825
05:36:13,720 --> 05:36:15,720
EACH OF THE COURSES HAVE A 

8826
05:36:15,720 --> 05:36:17,240
COURSE PAGE WHERE YOU CAN FIND 

8827
05:36:17,240 --> 05:36:18,720
MORE DETAILS ABOUT THE COURSES 

8828
05:36:18,720 --> 05:36:21,640
AND YOU CAN ALSO FIND MORE 

8829
05:36:21,640 --> 05:36:23,400
INFORMATION ABOUT THE AUTHORS, 

8830
05:36:23,400 --> 05:36:24,200
REVIEWERS AND LEADERSHIP FOR THE

8831
05:36:24,200 --> 05:36:30,040
COURSES AS WELL.

8832
05:36:30,040 --> 05:36:31,240
NOW I'LL MOVE TO ANOTHER BROWSER

8833
05:36:31,240 --> 05:36:36,640
WHERE I ALREADY SIGNED IN TO MY 

8834
05:36:36,640 --> 05:36:38,240
ACCOUNT ON THE ACCOUNT.

8835
05:36:38,240 --> 05:36:39,480
ONCE YOU LOG IN YOU'LL BE ABLE 

8836
05:36:39,480 --> 05:36:41,280
TO ACCESS ALL THE COURSES.

8837
05:36:41,280 --> 05:36:42,640
YOU CAN BEGIN MULTIPLE COURSES 

8838
05:36:42,640 --> 05:36:44,600
AT ONE TIME OR TAKE THEM ONE AT 

8839
05:36:44,600 --> 05:36:45,160
A TIME.

8840
05:36:45,160 --> 05:36:46,160
IT'S UP TO YOU.

8841
05:36:46,160 --> 05:36:48,360
IF I WERE TO EXPAND THIS COURSE 

8842
05:36:48,360 --> 05:36:50,040
FOR THE BENCH TO BEDSIDE, WHICH 

8843
05:36:50,040 --> 05:36:51,560
IS WHAT WE'RE LOOKING AT TODAY, 

8844
05:36:51,560 --> 05:36:53,960
IT WILL SHOW YOU THE MODULES, 

8845
05:36:53,960 --> 05:36:55,080
WHICH ONES YOU'VE BEGUN AND 

8846
05:36:55,080 --> 05:36:57,560
WHICH ONES YOU'VE COMPLETED AND 

8847
05:36:57,560 --> 05:37:01,840
THE DATE COMPLETED AS RELEVANT.

8848
05:37:01,840 --> 05:37:03,280
YOU'LL NOTE HERE IT'S SHOWING 

8849
05:37:03,280 --> 05:37:05,040
I'VE ALREADY TAKEN THE PRETEST 

8850
05:37:05,040 --> 05:37:06,840
SO IT'S ALLOWING KNOW NOW ACCESS

8851
05:37:06,840 --> 05:37:08,600
THE COURSE.

8852
05:37:08,600 --> 05:37:09,840
EACH MODULE WILL PRESENT TO YOU 

8853
05:37:09,840 --> 05:37:11,800
WITH LEARNING OBJECTIVES AT THE 

8854
05:37:11,800 --> 05:37:13,800
BEGINNING OF THE MODULE BUT 

8855
05:37:13,800 --> 05:37:15,320
BECAUSE I'M JUMPING TO THE 

8856
05:37:15,320 --> 05:37:20,520
MIDDLE OF THE COURSE YOU WON'T 

8857
05:37:20,520 --> 05:37:21,840
SEE THE LEARNING OBJECTIVES AT 

8858
05:37:21,840 --> 05:37:22,760
THE BEGINNING.

8859
05:37:22,760 --> 05:37:24,560
THIS IS JUMPING US INTO THE 

8860
05:37:24,560 --> 05:37:26,920
MIDDLE OF THE IMMUNOLOGY MODULE 

8861
05:37:26,920 --> 05:37:28,400
OF THE BENCH TO BEDSIDE COURSE.

8862
05:37:28,400 --> 05:37:31,960
AS WE NOTED THERE'S SIX 

8863
05:37:31,960 --> 05:37:32,640
DIFFERENT MODULES WITH DIFFERENT

8864
05:37:32,640 --> 05:37:34,240
HEALTH AND DISEASE AREAS.

8865
05:37:34,240 --> 05:37:36,440
THE AUDIO FOR THIS PAGE HAS 

8866
05:37:36,440 --> 05:37:37,680
ALREADY PLAYED BUT I'M HOPING IF

8867
05:37:37,680 --> 05:37:39,720
I ADVANCE TO THE NEXT SLIDE YOU 

8868
05:37:39,720 --> 05:37:41,240
CAN GET A LITTLE BIT OF A TASTE 

8869
05:37:41,240 --> 05:37:42,520
OF THE AUDIO.

8870
05:37:42,520 --> 05:37:44,600
SO HOPEFULLY THAT WILL PLAY FOR 

8871
05:37:44,600 --> 05:37:46,240
US IN A MOMENT.

8872
05:37:46,240 --> 05:37:49,080
>>MALES AND FEMALES ARE
NOT THE

8873
05:37:49,080 --> 05:37:49,280
SAME.

8874
05:37:49,280 --> 05:37:50,720
HERE ARE SOME OF THE WAYS IN 

8875
05:37:50,720 --> 05:37:53,520
WHICH SEX MATTERS IN ACHIEVING 

8876
05:37:53,520 --> 05:37:54,000
PERSONALIZED MEDICINE.

8877
05:37:54,000 --> 05:37:59,960
>>AS YOU CAN SEE THE
COURSE IS 

8878
05:37:59,960 --> 05:38:03,200
DYNAMIC AS USERS MOVE THROUGH 

8879
05:38:03,200 --> 05:38:04,400
THE COURSE THEY EXPLORE THE 

8880
05:38:04,400 --> 05:38:07,320
MATERIAL AT THEIR OWN PACE AND 

8881
05:38:07,320 --> 05:38:07,800
REMAIN ENGAGED.

8882
05:38:07,800 --> 05:38:09,720
I'M GOING CONTINUE -- 

8883
05:38:09,720 --> 05:38:11,760
>>ADDITIONALLY -- WE CAN 

8884
05:38:11,760 --> 05:38:12,600
CONTINUE THROUGH THE 

8885
05:38:12,600 --> 05:38:12,920
DEMONSTRATION.

8886
05:38:12,920 --> 05:38:15,720
ALL THE MODULES ARE INTERACTIVE 

8887
05:38:15,720 --> 05:38:18,280
WITH AUDIO, VIDEO AND CLICKABLE 

8888
05:38:18,280 --> 05:38:18,560
ELEMENTS.

8889
05:38:18,560 --> 05:38:22,720
I'M GOING KEEP THE AUDIO MUTED 

8890
05:38:22,720 --> 05:38:25,320
TO CONTINUE THROUGH THE 

8891
05:38:25,320 --> 05:38:25,720
DEMONSTRATION.

8892
05:38:25,720 --> 05:38:27,360
THIS PORTION ILLUSTRATES AN 

8893
05:38:27,360 --> 05:38:30,680
EXAMPLE OF HOW THE MOTH PROVIDES

8894
05:38:30,680 --> 05:38:34,800
SCIENTIFIC GRAPHICS WITH HELPFUL

8895
05:38:34,800 --> 05:38:39,200
INFORMATION AND SUITABLE FOR 

8896
05:38:39,200 --> 05:38:40,600
THOSE WHO DO WHILE BEING HELPFUL

8897
05:38:40,600 --> 05:38:42,600
TO THOSE WHO MAY NOT BE AS 

8898
05:38:42,600 --> 05:38:42,840
FAMILIAR.

8899
05:38:42,840 --> 05:38:47,200
AND I'LL POINT OUT THE GLASS  

8900
05:38:47,200 --> 05:38:48,240
GLOSSARY TOOL WHICH IS ANOTHER 

8901
05:38:48,240 --> 05:38:51,480
WAY WE'RE TRYING TO MAKE IT 

8902
05:38:51,480 --> 05:38:53,560
ACCESSIBLE EVEN TO THOSE WHO ARE

8903
05:38:53,560 --> 05:38:54,760
NOT NECESSARILY CLINICIANS AND 

8904
05:38:54,760 --> 05:38:55,640
HAVE A STRONG SCIENTIFIC 

8905
05:38:55,640 --> 05:39:04,240
BACKGROUND TO KNOW THE TERMS.

8906
05:39:04,240 --> 05:39:06,560
THIS NEXT PORTION HAS AN 

8907
05:39:06,560 --> 05:39:07,160
INTERACTIVE ELEMENT.

8908
05:39:07,160 --> 05:39:08,160
I'VE CLICKED THROUGH EVERYTHING 

8909
05:39:08,160 --> 05:39:10,160
HERE BUT THIS ALLOWS LEARNERS TO

8910
05:39:10,160 --> 05:39:12,360
SELECT WHAT THEY WOULD EXPECT TO

8911
05:39:12,360 --> 05:39:14,120
SEE IN THE INFLAMMATORY RESPONSE

8912
05:39:14,120 --> 05:39:16,440
BASED ON SEX DIFFERENCES AND 

8913
05:39:16,440 --> 05:39:17,840
PROGRESSION THROUGH THE LIFE 

8914
05:39:17,840 --> 05:39:18,080
COURSE.

8915
05:39:18,080 --> 05:39:20,600
IF I HADN'T CLICKED THROUGH 

8916
05:39:20,600 --> 05:39:22,000
EVERYTHING, IT WON'T ALLOW ME TO

8917
05:39:22,000 --> 05:39:24,480
ADVANCE YET AND THAT ALLOWS 

8918
05:39:24,480 --> 05:39:27,480
USERS -- YOU CAN DO IT AS MANY 

8919
05:39:27,480 --> 05:39:29,080
TIMES AS YOU WANT GOING BACK AND

8920
05:39:29,080 --> 05:39:29,960
FORTH AND GOING THROUGH PREVIOUS

8921
05:39:29,960 --> 05:39:32,600
PARTS OF THE COURSE AND DO THE 

8922
05:39:32,600 --> 05:39:37,440
ELEMENT AGAIN.

8923
05:39:37,440 --> 05:39:38,960
EACH SECTION OF THE COURSE IS 

8924
05:39:38,960 --> 05:39:41,560
UNIQUE IN HOW IT DISPLAYS THE 

8925
05:39:41,560 --> 05:39:43,480
INFORMATION TO REMAIN ENGAGING.

8926
05:39:43,480 --> 05:39:46,040
THIS BREAKS DOWN THE GENETIC AND

8927
05:39:46,040 --> 05:39:51,480
HORMONE INFLUENCE AND ECOLOGICAL

8928
05:39:51,480 --> 05:39:51,720
FACTORS.

8929
05:39:51,720 --> 05:39:53,320
CHECK MARKS INDICATE I VIEWED 

8930
05:39:53,320 --> 05:39:56,920
THE CONTENTS IN THE ELEMENT BUT 

8931
05:39:56,920 --> 05:39:59,520
IF I HADN'T I WOULDN'T CHECK AND

8932
05:39:59,520 --> 05:40:03,440
YOU WON'T HAVE TO WORRY ABOUT 

8933
05:40:03,440 --> 05:40:04,320
MISSING CONTENT.

8934
05:40:04,320 --> 05:40:05,640
WE ADVANCE TO THE KNOWLEDGE TAB 

8935
05:40:05,640 --> 05:40:08,600
AT THE END OF EACH SECTION AND 

8936
05:40:08,600 --> 05:40:09,960
YOU WILL BE PROVIDED INFORMATION

8937
05:40:09,960 --> 05:40:11,480
ABOUT WHETHER YOUR ANSWER IS 

8938
05:40:11,480 --> 05:40:13,800
CORRECT AND WHY OR WHY NOT AND 

8939
05:40:13,800 --> 05:40:14,800
THAT CONCLUDES OUR 

8940
05:40:14,800 --> 05:40:15,520
DEMONSTRATION.

8941
05:40:15,520 --> 05:40:17,000
I KNOW IT'S A SHORT 

8942
05:40:17,000 --> 05:40:18,400
DEMONSTRATION BUT WE HOPE IT'S 

8943
05:40:18,400 --> 05:40:19,840
GIVEN YOU A SENSE FOR THE 

8944
05:40:19,840 --> 05:40:22,560
QUALITY OF THE VALUE AND DEPTH 

8945
05:40:22,560 --> 05:40:24,600
OF THESE RESOURCES OFFERED AND 

8946
05:40:24,600 --> 05:40:26,720
PERHAPS SOME IDEAS HOW YOU MIGHT

8947
05:40:26,720 --> 05:40:29,200
BE ABLE TO DISSEMINATE OR 

8948
05:40:29,200 --> 05:40:32,880
INCORPORATE THESE RESOURCES INTO

8949
05:40:32,880 --> 05:40:34,240
DIFFERENT WORK THAT HAVE YOU OR 

8950
05:40:34,240 --> 05:40:35,800
COLLEAGUES YOU MIND MAY BE 

8951
05:40:35,800 --> 05:40:36,080
INTERESTED.

8952
05:40:36,080 --> 05:40:38,120
I'LL REMIND YOU THE CMEs ARE 

8953
05:40:38,120 --> 05:40:42,720
AVAILABLE JUST FOR THE BENCH TO 

8954
05:40:42,720 --> 05:40:44,200
BEDSIDE COURSE BUT THEY OFFER A 

8955
05:40:44,200 --> 05:40:44,720
CERTIFICATE AT THE END.

8956
05:40:44,720 --> 05:40:46,760
THANK YOU FOR YOUR TIME AND 

8957
05:40:46,760 --> 05:40:47,880
ATTENTION AND HOPEFULLY THIS 

8958
05:40:47,880 --> 05:40:49,600
GIVES YOU A GLIMPSE INTO THE 

8959
05:40:49,600 --> 05:40:51,120
GREAT RESOURCES THAT ARE 

8960
05:40:51,120 --> 05:40:52,000
AVAILABLE ON OUR E-LEARNING HOME

8961
05:40:52,000 --> 05:41:02,080
PAGE.

8962
05:41:03,120 --> 05:41:04,600
WITH THAT I'LL TURN IT BACK TO 

8963
05:41:04,600 --> 05:41:05,480
DR. NOURSI.

8964
05:41:05,480 --> 05:41:07,680
>>THANK YOU, EMILY AND 

8965
05:41:07,680 --> 05:41:08,160
ELIZABETH.

8966
05:41:08,160 --> 05:41:09,720
DR. CLAYTON, WE ARE SHARING NOW 

8967
05:41:09,720 --> 05:41:13,520
THE CORRECTED SLIDE FOR YOUR 

8968
05:41:13,520 --> 05:41:13,920
COMMENT.

8969
05:41:13,920 --> 05:41:15,720
>>PERFECT, THANK YOU.

8970
05:41:15,720 --> 05:41:24,400
DR. NOURSI.

8971
05:41:24,400 --> 05:41:26,440
>>I WANTED TO MAKE A
CORRECTION

8972
05:41:26,440 --> 05:41:32,080
ON ONE OF THE SLIDES FROM THE 

8973
05:41:32,080 --> 05:41:32,640
LUNCH BREAK.

8974
05:41:32,640 --> 05:41:36,600
THIS QUOTE WAS MISATTRIBUTED.

8975
05:41:36,600 --> 05:41:39,960
THE CORRECT ATTRIBUTION IS 

8976
05:41:39,960 --> 05:41:43,000
REBECCA SHANSKI'S LAB POSTED ON 

8977
05:41:43,000 --> 05:41:44,720
TWITTER AND WHAT WAS PREVIOUS 

8978
05:41:44,720 --> 05:41:46,520
POSTED WAS A RE-POSTING.

8979
05:41:46,520 --> 05:41:47,800
THIS IS THE ORIGINAL TWEET AND 

8980
05:41:47,800 --> 05:41:49,800
THE ORIGINAL TWEET'S OFFER.

8981
05:41:49,800 --> 05:41:51,600
WE APOLOGIZE FOR ANY MISTAKES 

8982
05:41:51,600 --> 05:41:53,880
AND FOR MAKING THAT MISTAKE IN 

8983
05:41:53,880 --> 05:41:54,400
THAT ATTRIBUTION.

8984
05:41:54,400 --> 05:41:55,040
THANK YOU SO MUCH FOR MAKING 

8985
05:41:55,040 --> 05:42:05,200
THAT CORRECTION FOR US.

8986
05:42:05,200 --> 05:42:08,040
AT THIS POINT WE HAVE A BIT OF 

8987
05:42:08,040 --> 05:42:11,360
TIME FOR OPEN DISCUSSION, OUR 

8988
05:42:11,360 --> 05:42:12,400
AFTERNOON OPEN DISCUSSION IN 

8989
05:42:12,400 --> 05:42:13,520
RESPONSE TO YOUR FEEDBACK TO 

8990
05:42:13,520 --> 05:42:14,960
MAKE SURE WE HAD TIME ON THE 

8991
05:42:14,960 --> 05:42:16,640
AGENDA THROUGHOUT FOR ENGAGEMENT

8992
05:42:16,640 --> 05:42:18,000
WITH YOU ALL AS ADVISORY 

8993
05:42:18,000 --> 05:42:18,720
COMMITTEE MEMBERS.

8994
05:42:18,720 --> 05:42:22,640
I INVITE YOU TO TURN ON YOUR 

8995
05:42:22,640 --> 05:42:25,640
CAMERAS AND BRING UP ANY ISSUES 

8996
05:42:25,640 --> 05:42:29,480
OR TOPICS THAT YOU WOULD LIKE TO

8997
05:42:29,480 --> 05:42:31,760
SHARE YOUR THOUGHTS ABOUT 

8998
05:42:31,760 --> 05:42:36,640
ESPECIALLY ANYONE WHO HAS NOT 

8999
05:42:36,640 --> 05:42:37,800
CONTRIBUTED YET AND CONTRIBUTE 

9000
05:42:37,800 --> 05:42:39,320
IN THE CHAT IF YOU PREFER BUT 

9001
05:42:39,320 --> 05:42:42,680
LET ME JUST OPEN THE FLOOR TO 

9002
05:42:42,680 --> 05:42:47,880
HEAR FROM YOU ALL AS ADVISORY 

9003
05:42:47,880 --> 05:42:50,520
COMMITTEE MEMBERS.

9004
05:42:50,520 --> 05:42:54,160
AND YOUR INPUT IS SO IMPORTANT 

9005
05:42:54,160 --> 05:42:56,240
TO US AND SO WOULD LIKE TO HEAR 

9006
05:42:56,240 --> 05:42:58,040
ANY OTHER THOUGHT OR FEEDBACK OR

9007
05:42:58,040 --> 05:43:00,120
COMMENTS ON ORWH PROGRAMMING.

9008
05:43:00,120 --> 05:43:10,520
WHO WOULD LIKE TO START?

9009
05:43:21,400 --> 05:43:23,520
>>CAN YOU ASK TO YOU
COMMENT 

9010
05:43:23,520 --> 05:43:24,600
BRIEFLY ON THE IMPORTANCE OF 

9011
05:43:24,600 --> 05:43:25,640
TRAUMA AND VIOLENCE IN WOMEN AND

9012
05:43:25,640 --> 05:43:27,000
WHAT WE SHOULD BE THINKING ABOUT

9013
05:43:27,000 --> 05:43:29,280
AS WE MOVE FORWARD?

9014
05:43:29,280 --> 05:43:31,960
THAT'S A TOPIC THAT'S BEEN VERY 

9015
05:43:31,960 --> 05:43:35,040
IMPORTANT TO ORWH OVER THE YEARS

9016
05:43:35,040 --> 05:43:37,200
AND WE HAVE MADE SUBSTANTIAL 

9017
05:43:37,200 --> 05:43:39,200
INVESTMENTS IN THE PATH WITH 

9018
05:43:39,200 --> 05:43:40,040
COLLABORATING WITH HHS AND 

9019
05:43:40,040 --> 05:43:43,400
ACROSS THE OPERATING DIVISIONS 

9020
05:43:43,400 --> 05:43:46,040
TO PUT FORWARD SOME RESEARCH 

9021
05:43:46,040 --> 05:43:46,320
QUESTIONS.

9022
05:43:46,320 --> 05:43:51,560
IT'S A CROSS-CUTTING TOPIC THAT 

9023
05:43:51,560 --> 05:43:52,680
WE BELIEVE DOES DESERVE SOME 

9024
05:43:52,680 --> 05:43:57,560
INCREASED ATTENTION BUT I WOULD 

9025
05:43:57,560 --> 05:43:59,800
LIKE TO HEAR FROM OTHERS AND 

9026
05:43:59,800 --> 05:44:01,600
YOUR OUTSTANDING WORK IN THE 

9027
05:44:01,600 --> 05:44:02,880
SPACE IS WHY I'M CALLING FOR YOU

9028
05:44:02,880 --> 05:44:05,440
TO GET US STARTED ON THAT.

9029
05:44:05,440 --> 05:44:09,760
>>WHAT IS INTERESTING IS
I 

9030
05:44:09,760 --> 05:44:12,600
THINK THE CDC REPORT YOU 

9031
05:44:12,600 --> 05:44:14,000
REFERENCED EARLIER ABOUT PRE

9032
05:44:14,000 --> 05:44:16,920
PREVENTIBLE DEATHS DURING 

9033
05:44:16,920 --> 05:44:17,240
PREGNANCY.

9034
05:44:17,240 --> 05:44:23,480
WE KNOW THERE'S A HIGH RATE OF 

9035
05:44:23,480 --> 05:44:24,160
PREGNANCY ASSOCIATED OF KILLING 

9036
05:44:24,160 --> 05:44:27,680
WOMEN AND INJURY AND THE RESULT 

9037
05:44:27,680 --> 05:44:28,920
OF INTIMATE PARTNER VIOLENCE.

9038
05:44:28,920 --> 05:44:32,280
I THINK IT'S A CROSS-CUTTING 

9039
05:44:32,280 --> 05:44:35,440
TOPICS THAT HAS BEEN MENTIONED 

9040
05:44:35,440 --> 05:44:40,080
SEVERAL TIMES BECAUSE WE KNOW 

9041
05:44:40,080 --> 05:44:48,000
FEMALE CHILDREN AND I DON'T DO 

9042
05:44:48,000 --> 05:44:49,840
CHILD ABUSE AND WE KNOW FEMALE 

9043
05:44:49,840 --> 05:44:50,960
CHILDREN ARE EXPOSED ACROSS THE 

9044
05:44:50,960 --> 05:44:52,800
LIFE SPAN.

9045
05:44:52,800 --> 05:44:56,280
IT CAN BEGIN IN INFANCY, 

9046
05:44:56,280 --> 05:45:00,440
ADOLESCENT DATING, YOUNG ADULT 

9047
05:45:00,440 --> 05:45:05,800
WOMEN AND ON AND I'VE DONE SOME 

9048
05:45:05,800 --> 05:45:09,240
WORK WITH OLDER WOMEN AND 

9049
05:45:09,240 --> 05:45:09,520
VIOLENCE.

9050
05:45:09,520 --> 05:45:12,880
IT'S THROUGH THROUGHOUT THE LIFE

9051
05:45:12,880 --> 05:45:15,360
TIME FOR MOST WOMEN AND WE KNOW 

9052
05:45:15,360 --> 05:45:16,600
MANY PEOPLE CONCENTRATE ON THE 

9053
05:45:16,600 --> 05:45:19,280
ACUTE INCIDENTS OF THE BATTERING

9054
05:45:19,280 --> 05:45:25,720
OR THE INJURY OR THE E.R. VISIT 

9055
05:45:25,720 --> 05:45:27,600
BUT THERE'S OTHER RESEARCH AND 

9056
05:45:27,600 --> 05:45:31,840
WORK I'VE DONE WITH DR. JACKIE 

9057
05:45:31,840 --> 05:45:33,160
CAMPBELL THERE'S LIFELONG 

9058
05:45:33,160 --> 05:45:34,600
EFFECTS WHICH PROBABLY I THINK 

9059
05:45:34,600 --> 05:45:40,920
YOU COULD LOOK AT IN TERMS OF 

9060
05:45:40,920 --> 05:45:42,200
CHRONIC CONDITIONS DISABLING 

9061
05:45:42,200 --> 05:45:44,160
CONDITIONS AND SOME OF OUR 

9062
05:45:44,160 --> 05:45:48,480
EARLIER WORK LINKED SOME 

9063
05:45:48,480 --> 05:45:50,840
EXPOSURE TO HYPERTENSION AND 

9064
05:45:50,840 --> 05:45:51,800
CARDIAC DISEASE.

9065
05:45:51,800 --> 05:45:55,200
I ALWAYS THINK OF MY Ph.D. 

9066
05:45:55,200 --> 05:45:57,760
ADVISER ABOUT WHAT IS SEXY AND 

9067
05:45:57,760 --> 05:45:58,960
WE HAVE PERIODS AND THINGS ARE 

9068
05:45:58,960 --> 05:46:00,560
IMPORTANT THAT ARE NOT IMPORTANT

9069
05:46:00,560 --> 05:46:03,800
AND THINGS THAT FIT HIGH 

9070
05:46:03,800 --> 05:46:06,720
PRIORITY AND WE'RE IN ACROSS THE

9071
05:46:06,720 --> 05:46:09,440
INSTITUTES WE'RE SHYING AWAY 

9072
05:46:09,440 --> 05:46:14,920
FROM VIOLENCE AND THE IMPACT ON 

9073
05:46:14,920 --> 05:46:19,800
HEALTH BUT WE KNOW IT'S THERE 

9074
05:46:19,800 --> 05:46:21,400
AND NEED TO CONTINUE 

9075
05:46:21,400 --> 05:46:22,560
TRAUMA-INFORMED WHEN YOU LOOK AT

9076
05:46:22,560 --> 05:46:24,600
THE DISEASES YOU WERE TALKING 

9077
05:46:24,600 --> 05:46:26,800
ABOUT OR CONDITIONS FOR YOUR NEW

9078
05:46:26,800 --> 05:46:29,000
STRATEGIC PLAN AND MENTAL 

9079
05:46:29,000 --> 05:46:31,120
HEALTH, SUBSTANCE ABUSE WE KNOW 

9080
05:46:31,120 --> 05:46:35,440
ARE LONG-TERM CONSEQUENCES OF 

9081
05:46:35,440 --> 05:46:36,280
EXPOSURE TO VIOLENCE AND WHEN WE

9082
05:46:36,280 --> 05:46:38,400
THINK ABOUT WOMEN AND THE HIGHER

9083
05:46:38,400 --> 05:46:40,600
RATES OF MENTAL HEALTH AND 

9084
05:46:40,600 --> 05:46:43,320
DEPRESSION AND PARTICULARLY IN 

9085
05:46:43,320 --> 05:46:46,720
VULNERABLE COMMUNITIES AND OFTEN

9086
05:46:46,720 --> 05:46:51,560
THOSE WOMEN ARE NOT -- THEY'RE 

9087
05:46:51,560 --> 05:46:53,160
NOT SURE IT'S DEPRESSION OR HAVE

9088
05:46:53,160 --> 05:46:55,560
HAD THAT LABEL.

9089
05:46:55,560 --> 05:46:58,200
I THINK WE HAVE TO CONTINUE AND 

9090
05:46:58,200 --> 05:47:02,160
CERTAINLY WE ARE ALSO SEEING THE

9091
05:47:02,160 --> 05:47:04,640
IMPACT OF VIOLENCE AGAINST WILL 

9092
05:47:04,640 --> 05:47:06,840
HAVES AROUND GENDER STUDIES.

9093
05:47:06,840 --> 05:47:08,520
AND HOW DO WE LOOK AT THAT AND 

9094
05:47:08,520 --> 05:47:11,560
HOW DO WE STUDY THAT 

9095
05:47:11,560 --> 05:47:16,640
PARTICULARLY IN YOUNGER COHORTS 

9096
05:47:16,640 --> 05:47:18,760
OF YOUNG WOMEN AND PERHAPS 

9097
05:47:18,760 --> 05:47:23,240
INFLUENCE GENDERED INDIVIDUALS.

9098
05:47:23,240 --> 05:47:27,760
I THINK IT'S IMPORTANT THAT 

9099
05:47:27,760 --> 05:47:33,160
ISSUE CONTINUES AND WE KNOW THAT

9100
05:47:33,160 --> 05:47:35,960
THAT PREGNANCY RELATED DEATHS 

9101
05:47:35,960 --> 05:47:37,440
AND MATERNAL MORTALITY -- MORE 

9102
05:47:37,440 --> 05:47:38,600
WOMEN ARE GOING TO BE EXPOSED TO

9103
05:47:38,600 --> 05:47:40,080
THAT THAN SOME OF THE OTHER 

9104
05:47:40,080 --> 05:47:42,160
MEDICAL CONDITIONS THAT WE STUDY

9105
05:47:42,160 --> 05:47:45,640
AND I THINK IT'S A PERVASIVE AND

9106
05:47:45,640 --> 05:47:48,640
I THINK WE'RE SEEING THE 

9107
05:47:48,640 --> 05:47:50,600
PANDEMIC HAS INCREASED MANY 

9108
05:47:50,600 --> 05:47:52,920
WOMEN'S VULNERABILITY TO 

9109
05:47:52,920 --> 05:47:56,320
PARTICULARLY INTIMATE PARTNER 

9110
05:47:56,320 --> 05:47:56,600
VIOLENCE.

9111
05:47:56,600 --> 05:47:57,560
>>THANK YOU SO MUCH FOR
SHARING

9112
05:47:57,560 --> 05:47:58,120
YOUR THOUGHTS.

9113
05:47:58,120 --> 05:48:00,600
ANYBODY ELSE WANT TO PICK UP ON 

9114
05:48:00,600 --> 05:48:03,800
THAT OR ADD TO THAT BEFORE WE 

9115
05:48:03,800 --> 05:48:05,160
MOVE ON TO ANOTHER TOPIC?

9116
05:48:05,160 --> 05:48:12,480
THANK YOU, DR. SHARPS.

9117
05:48:12,480 --> 05:48:14,800
I APPRECIATE THAT.

9118
05:48:14,800 --> 05:48:18,240
I WONDER IF I CAN GET A COMMENT 

9119
05:48:18,240 --> 05:48:20,600
ON CANCER AND WOMEN AND IT'S 

9120
05:48:20,600 --> 05:48:22,080
SOMETHING IMPORTANT TO US IN THE

9121
05:48:22,080 --> 05:48:23,640
WOMEN'S HEALTH CONFERENCE REPORT

9122
05:48:23,640 --> 05:48:26,400
WE TALKED ABOUT STALLED CERVICAL

9123
05:48:26,400 --> 05:48:27,720
CANCER SURVIVOR RATES.

9124
05:48:27,720 --> 05:48:30,440
WE HAVE A NEW NCI DIRECTOR 

9125
05:48:30,440 --> 05:48:30,680
COMING.

9126
05:48:30,680 --> 05:48:36,160
SHE'S HERE, ACTUALLY.

9127
05:48:36,160 --> 05:48:36,800
GETTING ON HER CALENDAR.

9128
05:48:36,800 --> 05:48:39,120
I WOULD LIKE TO HEAR IF THERE'S 

9129
05:48:39,120 --> 05:48:40,600
SPECIFIC THOUGHTS FOR US AS WE 

9130
05:48:40,600 --> 05:48:42,800
GO INTO THE PERIOD OF HAVING THE

9131
05:48:42,800 --> 05:48:44,440
THINK TANKS THAT WILL INFORM OUR

9132
05:48:44,440 --> 05:48:46,000
STRATEGIC GOALS GOING FORWARD.

9133
05:48:46,000 --> 05:48:48,480
>>I'M SUPER EXCITED ABOUT

9134
05:48:48,480 --> 05:48:51,600
MONICA BECOMING HEAD OF THE NCI 

9135
05:48:51,600 --> 05:48:52,880
AND SHE IS EXTRAORDINARY AND SO 

9136
05:48:52,880 --> 05:48:56,320
I'M LOOKING FORWARD TO SEE WHAT 

9137
05:48:56,320 --> 05:49:01,000
CHANGES OCCUR.

9138
05:49:01,000 --> 05:49:05,040
I THINK THAT ONE REALLY 

9139
05:49:05,040 --> 05:49:07,680
INTERESTING THING AS PART OF THE

9140
05:49:07,680 --> 05:49:09,760
LANCET COMMISSION ON BREAST 

9141
05:49:09,760 --> 05:49:12,240
CANCER WHICH IS A CONDITION THAT

9142
05:49:12,240 --> 05:49:13,400
DISPROPORTIONATELY AFFECTS WOMEN

9143
05:49:13,400 --> 05:49:17,640
AND BEING A TRACER CONDITION WE 

9144
05:49:17,640 --> 05:49:20,640
CAN USE TO HELP TO HIGHLIGHT 

9145
05:49:20,640 --> 05:49:23,680
WAYS THAT WOMEN CAN BE EMPOWERED

9146
05:49:23,680 --> 05:49:25,400
MORE GENERALLY AND WE'RE LOOKING

9147
05:49:25,400 --> 05:49:27,040
AT THE LITERATURE ON BREAST 

9148
05:49:27,040 --> 05:49:28,680
CANCER RIGHT NOW AND LOOKING 

9149
05:49:28,680 --> 05:49:33,960
ACROSS HIGH-INCOME AND LOW AND 

9150
05:49:33,960 --> 05:49:35,240
MIDDLE-INCOME COUNTRY SETTING 

9151
05:49:35,240 --> 05:49:37,600
AND THE OPTIONS ARE VERY 

9152
05:49:37,600 --> 05:49:38,760
DIFFERENT IN DIFFERENT SETTINGS 

9153
05:49:38,760 --> 05:49:40,560
YET THERE IS ALWAYS A CHOICE AND

9154
05:49:40,560 --> 05:49:42,480
CONSISTENT TRUTH WHICH IS GENDER

9155
05:49:42,480 --> 05:49:45,440
OF THE INDIVIDUAL IS SOMETHING 

9156
05:49:45,440 --> 05:49:47,000
THAT DISADVANTAGES AND BEING A 

9157
05:49:47,000 --> 05:49:47,600
WOMAN DISADVANTAGES YOU 

9158
05:49:47,600 --> 05:49:48,640
REGARDLESS OF WHETHER YOU'RE IN 

9159
05:49:48,640 --> 05:49:51,760
A HIGH-INCOME OR LOW-INCOME 

9160
05:49:51,760 --> 05:49:53,440
COUNTRY AND THAT EXTENDS FROM 

9161
05:49:53,440 --> 05:50:01,000
THE IMPACT OF THE DOBBS DECISION

9162
05:50:01,000 --> 05:50:04,280
HERE TO OTHER SETTINGS.

9163
05:50:04,280 --> 05:50:05,720
WE HAVE THE GENDER SPECIFIC 

9164
05:50:05,720 --> 05:50:09,760
CANCERS AND THE ONES THAT AFFECT

9165
05:50:09,760 --> 05:50:12,560
PEOPLE WHO HAVE UTERUSES AND 

9166
05:50:12,560 --> 05:50:14,200
AFFECT WOMEN LIKE BREAST CANCER 

9167
05:50:14,200 --> 05:50:16,000
AND OBVIOUSLY ALL GENDERS HAVE 

9168
05:50:16,000 --> 05:50:17,160
BREAST BUT IT'S MUCH MORE COMMON

9169
05:50:17,160 --> 05:50:20,600
IN WOMEN AND HOW CAN WE 

9170
05:50:20,600 --> 05:50:25,640
POTENTIALLY LEVERAGE EFFORTS TO 

9171
05:50:25,640 --> 05:50:28,240
COMBAT THOSE SPECIFIC DISEASES 

9172
05:50:28,240 --> 05:50:30,840
TO INFORM AND ELEVATE WOMEN'S 

9173
05:50:30,840 --> 05:50:32,520
RIGHT AND JUSTICE MORE GENERALLY

9174
05:50:32,520 --> 05:50:36,600
AND I THINK THERE'S ALSO ROOM 

9175
05:50:36,600 --> 05:50:40,240
FOR US TO CONTINUE TO SEX AS A 

9176
05:50:40,240 --> 05:50:40,880
BIOLOGICAL VARIABLE AND 

9177
05:50:40,880 --> 05:50:43,480
INCLUSION OF WOMEN IN RESEARCH 

9178
05:50:43,480 --> 05:50:54,000
FOR NON-SEX DISTRIBUTED CANCERS.

9179
05:50:58,400 --> 05:51:03,240
AND FIGURE OUT WAYS WE CAN USE 

9180
05:51:03,240 --> 05:51:03,920
THIS MOMENT TO NEVERTHELESS 

9181
05:51:03,920 --> 05:51:06,880
ADVANCE THE HEALTH OF WOMEN.

9182
05:51:06,880 --> 05:51:10,400
>>I APPRECIATE THAT.

9183
05:51:10,400 --> 05:51:20,960
>>OTHER THOUGHTS IN THE
GROUP?

9184
05:51:26,840 --> 05:51:28,040
>>JUST A QUICK THOUGHT.

9185
05:51:28,040 --> 05:51:36,000
THESE ARE ALL REALLY IMPORTANT 

9186
05:51:36,000 --> 05:51:37,000
INCREDIBLE PROBLEMS FOR US.

9187
05:51:37,000 --> 05:51:38,400
SOMETIMES IT'S OVERWHELMING.

9188
05:51:38,400 --> 05:51:41,880
I THINK WHEN WE PRESENT THESE 

9189
05:51:41,880 --> 05:51:44,600
PROBLEMS I THINK WE HAVE TO ASK 

9190
05:51:44,600 --> 05:51:47,480
OURSELVES WHAT'S THE 

9191
05:51:47,480 --> 05:51:47,880
DELIVERABLES?

9192
05:51:47,880 --> 05:51:48,120
.

9193
05:51:48,120 --> 05:51:50,440
YOU GOT THIS PROBLEM, WHAT'S THE

9194
05:51:50,440 --> 05:51:50,760
DELIVERABLE?

9195
05:51:50,760 --> 05:51:53,120
HOW CAN IT BE FACED IN A WAY 

9196
05:51:53,120 --> 05:51:55,080
THAT'S GOING TO LEAD TO 

9197
05:51:55,080 --> 05:51:57,120
SOMETHING, YOU KNOW WHAT I MEAN?

9198
05:51:57,120 --> 05:52:00,000
JUST LIKE WHEN YOU WRITE A 

9199
05:52:00,000 --> 05:52:01,400
GRANT, YOU HAVE TO PROVIDE WHAT 

9200
05:52:01,400 --> 05:52:02,600
ARE YOU GOING GET OUT OF THE 

9201
05:52:02,600 --> 05:52:03,240
GRANT?

9202
05:52:03,240 --> 05:52:04,760
WHAT'S THE DELIVERABLE.

9203
05:52:04,760 --> 05:52:07,160
THAT'S WHAT I WANTED TO SAY.

9204
05:52:07,160 --> 05:52:09,440
>>SCOTT, KEEPING US ON
POINT.

9205
05:52:09,440 --> 05:52:12,320
THE QUESTION I ASKED MYSELF IS 

9206
05:52:12,320 --> 05:52:12,880
TO WHAT END.

9207
05:52:12,880 --> 05:52:14,560
THAT'S HOW I FORCE MYSELF TO 

9208
05:52:14,560 --> 05:52:16,880
THINK ABOUT WELL, WHY ARE YOU 

9209
05:52:16,880 --> 05:52:17,360
DOING THIS?

9210
05:52:17,360 --> 05:52:19,880
WE HAVE EXTREMELY LIMITED 

9211
05:52:19,880 --> 05:52:21,520
RESOURCES TO DO A LOT.

9212
05:52:21,520 --> 05:52:23,960
SAID IT CAN BE OVERWHELMING, THE

9213
05:52:23,960 --> 05:52:25,640
NEEDS ARE OVERWHELMING.

9214
05:52:25,640 --> 05:52:31,120
THE NEEDS OF WOMEN ARE OV

9215
05:52:31,120 --> 05:52:33,800
OVERWHELMING BECAUSE WE HAVE 

9216
05:52:33,800 --> 05:52:35,120
GAPS IN KNOWLEDGE BECAUSE OF THE

9217
05:52:35,120 --> 05:52:38,240
WAY WE HISTORICALLY CONDUCTED 

9218
05:52:38,240 --> 05:52:39,800
OUR RESEARCH AND NOT ALWAYS 

9219
05:52:39,800 --> 05:52:41,880
HAVING PATHWAYS TO ADDRESS THE 

9220
05:52:41,880 --> 05:52:42,640
ARTICULATED NEEDS OF ALL WOMEN 

9221
05:52:42,640 --> 05:52:44,960
WITH THEIR LIVED EXPERIENCES AND

9222
05:52:44,960 --> 05:52:45,800
UNIQUE PERSPECTIVES.

9223
05:52:45,800 --> 05:52:50,280
BECAUSE THIS IS EVOLVING.

9224
05:52:50,280 --> 05:52:52,280
AND WE'VE ONLY BEEN AROUND AELT 

9225
05:52:52,280 --> 05:52:55,160
A LITTLE OVER 30 YEARS.

9226
05:52:55,160 --> 05:52:57,880
-- A LITTLE OVER 30 YEARS.

9227
05:52:57,880 --> 05:52:59,560
IT'S IMPORTANT TO THINK TO WHAT 

9228
05:52:59,560 --> 05:53:02,000
END AND TO THINK ABOUT WHICH OF 

9229
05:53:02,000 --> 05:53:04,800
THE -- WHAT SCIENCE IS POISED TO

9230
05:53:04,800 --> 05:53:08,600
MOVE FORWARD NOW AND WHAT THINGS

9231
05:53:08,600 --> 05:53:09,200
MIGHT NEED INFRASTRUCTURE 

9232
05:53:09,200 --> 05:53:10,680
INVESTMENT NOW TO BE ABLE TO DO 

9233
05:53:10,680 --> 05:53:12,680
WHAT'S NEEDED IN THE FUTURE TO 

9234
05:53:12,680 --> 05:53:15,240
BE ABLE TO THINK ABOUT THAT ALL 

9235
05:53:15,240 --> 05:53:17,880
AT THE SAME TIME AND IN A 

9236
05:53:17,880 --> 05:53:20,600
COMPLEX SYSTEM THAT HAS CHANGE 

9237
05:53:20,600 --> 05:53:21,280
BEING PARTS.

9238
05:53:21,280 --> 05:53:22,800
SOMETIMES YOU FEEL LIKE THE 

9239
05:53:22,800 --> 05:53:24,120
FLOOR'S MOVING UNDER YOU.

9240
05:53:24,120 --> 05:53:26,680
I THINK WE ALL FEEL THAT WAY.

9241
05:53:26,680 --> 05:53:32,280
I AM TOTALLY STEADY HOWEVER, BY 

9242
05:53:32,280 --> 05:53:38,400
THE NEED TO PUT SCIENCE TO WORK 

9243
05:53:38,400 --> 05:53:40,800
FOR ALL WOMEN AND WHY I'M HERE 

9244
05:53:40,800 --> 05:53:43,160
AND ALL ORWH IS HERE.

9245
05:53:43,160 --> 05:53:45,360
WE REALIZE THAT WE CAN'T DO IT 

9246
05:53:45,360 --> 05:53:46,080
ALL ALONE.

9247
05:53:46,080 --> 05:53:50,000
SO PARTNERSHIPS AND 

9248
05:53:50,000 --> 05:53:51,840
COLLABORATIONS YOU SEE HOW WE 

9249
05:53:51,840 --> 05:53:56,280
CONNECT WITH OUR PARTNERS.

9250
05:53:56,280 --> 05:53:57,640
I HEAR YOU SCOTT.

9251
05:53:57,640 --> 05:53:58,440
TO WHAT END.

9252
05:53:58,440 --> 05:54:00,120
>>WELL SAID, THANK YOU.

9253
05:54:00,120 --> 05:54:01,960
>>THAT'S THE WAY I THINK
ABOUT 

9254
05:54:01,960 --> 05:54:03,160
IT.

9255
05:54:03,160 --> 05:54:04,760
LET'S GO TO DR. McGREGOR AND 

9256
05:54:04,760 --> 05:54:09,000
DR. SIMON.

9257
05:54:09,000 --> 05:54:11,560
>>I LOVE HEARING YOU SAY
THAT, 

9258
05:54:11,560 --> 05:54:12,080
THAT'S WONDERFUL.

9259
05:54:12,080 --> 05:54:14,960
A QUICK THING TO DISCUSS IS THE 

9260
05:54:14,960 --> 05:54:19,480
BENCH TO BEDSIDE.

9261
05:54:19,480 --> 05:54:21,440
IT KIND OF OF THE RECENT COMMENT

9262
05:54:21,440 --> 05:54:23,240
HOW CAN WE MAKE THAT QUICKER?

9263
05:54:23,240 --> 05:54:27,880
I KNOW THE R35 GENDER GRANTS 

9264
05:54:27,880 --> 05:54:30,040
HAVE TO DO WITH EXTRA CURRICULUM

9265
05:54:30,040 --> 05:54:32,120
AND RIGOR AND I'M SPREADING THAT

9266
05:54:32,120 --> 05:54:33,840
FAR AND WIDE BUT WHEN THERE ARE 

9267
05:54:33,840 --> 05:54:37,720
SO MANY THINGS WHEN IT IS SO 

9268
05:54:37,720 --> 05:54:38,880
OVERWHELMING AND WE'RE SEEING 

9269
05:54:38,880 --> 05:54:40,280
ALL THE GREAT RESEARCH HAPPENING

9270
05:54:40,280 --> 05:54:43,400
NOW, ARE THERE WAYS THAT WE CAN 

9271
05:54:43,400 --> 05:54:46,000
START TO ALSO THINK ABOUT HOW TO

9272
05:54:46,000 --> 05:54:48,600
IMPLEMENT THIS IN PATIENT CARE?

9273
05:54:48,600 --> 05:54:53,040
IT TAKES FOREVER?

9274
05:54:53,040 --> 05:54:55,600
ALL THIS AMAZING THINGS I'M 

9275
05:54:55,600 --> 05:54:57,280
HEARING AND I GO TO MY SHIFT AN 

9276
05:54:57,280 --> 05:54:59,720
IT'S NOT IMPLEMENTED AT ALL.

9277
05:54:59,720 --> 05:55:01,440
THAT'S WHERE I GET DOWN TRODDEN.

9278
05:55:01,440 --> 05:55:04,280
HOW CAN WE MAKE THIS A QUICKER 

9279
05:55:04,280 --> 05:55:04,560
TRANSLATION?

9280
05:55:04,560 --> 05:55:06,800
>>THAT'S VERY HELPFUL,
ALLISON,

9281
05:55:06,800 --> 05:55:08,920
YOU'RE RIGHT.

9282
05:55:08,920 --> 05:55:11,680
WE'VE BEEN TALKING ABOUT 

9283
05:55:11,680 --> 05:55:12,360
ELECTRONIC HEALTH RECORDS COULD 

9284
05:55:12,360 --> 05:55:13,040
BE DECISION SUPPORT TOOLS 

9285
05:55:13,040 --> 05:55:14,520
BECAUSE WHEN WE HAVE THE 

9286
05:55:14,520 --> 05:55:17,800
EVIDENCE THAT THERE ARE 

9287
05:55:17,800 --> 05:55:19,920
DIFFERENCES, FOR EXAMPLE, IN 

9288
05:55:19,920 --> 05:55:20,600
PARTICULAR LABORATORY BLOOD 

9289
05:55:20,600 --> 05:55:23,000
VALUES OR HOW YOU SHOULD BE 

9290
05:55:23,000 --> 05:55:26,800
ORDERING TESTS YOU SHOULD BE 

9291
05:55:26,800 --> 05:55:29,760
GIVING OR ARE YOU DIAGNOSING 

9292
05:55:29,760 --> 05:55:32,600
CHRONIC KIDNEY DISEASE AND SO 

9293
05:55:32,600 --> 05:55:35,040
OPPORTUNITIES I'M HEARING FROM 

9294
05:55:35,040 --> 05:55:36,600
YOU IS I'M HEARING OPPORTUNITIES

9295
05:55:36,600 --> 05:55:43,520
TO SUPPORT THE AM SELL -- 

9296
05:55:43,520 --> 05:55:44,440
ACCELERATION OF THE EVIDENCE WE 

9297
05:55:44,440 --> 05:55:47,520
ALREADY HAVE TO GET TO WOMEN 

9298
05:55:47,520 --> 05:55:55,200
FASTER AND AFFECT THE 

9299
05:55:55,200 --> 05:55:55,760
CLINIC-PATIENT-CLINICIAN 

9300
05:55:55,760 --> 05:55:56,200
INTERACTION AS WELL.

9301
05:55:56,200 --> 05:55:59,440
>>AND THANKS FOR WHAT YOU
SAID 

9302
05:55:59,440 --> 05:56:00,880
ABOUT NEEDING SCIENCE TO WORK 

9303
05:56:00,880 --> 05:56:01,560
FOR ALL.

9304
05:56:01,560 --> 05:56:05,600
ALL PEOPLE WHO IDENTIFY AS WOMEN

9305
05:56:05,600 --> 05:56:06,680
AND THAT'S GREAT.

9306
05:56:06,680 --> 05:56:08,960
FOR THE COMMENT ON NOT ONLY WHAT

9307
05:56:08,960 --> 05:56:14,520
IS THE DRIVELIVERABLE WE TO THI 

9308
05:56:14,520 --> 05:56:16,600
ABOUT WHAT BROUGHT US HERE IN 

9309
05:56:16,600 --> 05:56:18,080
THE FIRST PLACE.

9310
05:56:18,080 --> 05:56:21,080
WHY ARE THINGS HAPPENING THE WAY

9311
05:56:21,080 --> 05:56:22,280
THEY ARE FOR SOME PEOPLE AND 

9312
05:56:22,280 --> 05:56:27,400
OTHER WAYS FOR OTHER PEOPLE.

9313
05:56:27,400 --> 05:56:29,960
HEALTH INEQUITIES AS A RESULT OF

9314
05:56:29,960 --> 05:56:31,840
SOME THINGS AND THEY'RE DAUNTING

9315
05:56:31,840 --> 05:56:32,840
PROBLEMS BUT IF YOU LOOK UNDER 

9316
05:56:32,840 --> 05:56:34,000
THE HOOD OF THE CAR AND 

9317
05:56:34,000 --> 05:56:38,120
STRUCTURES THAT CAUSED US TO BE 

9318
05:56:38,120 --> 05:56:40,680
HERE, THAT'S WHERE WE NEED TO 

9319
05:56:40,680 --> 05:56:42,760
GO, UP STREAK AND ROOT CAUSE.

9320
05:56:42,760 --> 05:56:44,880
NOT JUST WHAT'S THE DELIVERABLE 

9321
05:56:44,880 --> 05:56:46,440
BUT WHAT BROUGHT US HERE AND 

9322
05:56:46,440 --> 05:56:48,920
WHAT ARE THE PHENOTYPES WE SEE 

9323
05:56:48,920 --> 05:56:49,480
AS IS?

9324
05:56:49,480 --> 05:56:51,280
AND THE BENCH TO BEDSIDE IS 

9325
05:56:51,280 --> 05:56:53,920
SUPER IMPORTANT BUT IT BECOMES 

9326
05:56:53,920 --> 05:56:54,600
MORE TRANSLATABLE.

9327
05:56:54,600 --> 05:56:57,240
THE TRANSLATIONAL SCIENCE 

9328
05:56:57,240 --> 05:57:00,200
BECOMES MORE TRANSLATABLE 

9329
05:57:00,200 --> 05:57:01,400
ARGUABLY CONSISTENTLY WHEN WE 

9330
05:57:01,400 --> 05:57:02,600
INVOLVE COMMUNITY AND CENTER 

9331
05:57:02,600 --> 05:57:04,440
COMMUNITY AND NOT JUST ENGAGE 

9332
05:57:04,440 --> 05:57:05,520
COMMUNITY ON THE SIDE LIKE AN 

9333
05:57:05,520 --> 05:57:06,440
ADVISORY BOARD BUT WHEN WE 

9334
05:57:06,440 --> 05:57:08,880
CENTER THE VOICES OF PEOPLE WHO 

9335
05:57:08,880 --> 05:57:11,360
IDENTIFY AS WOMEN IN WOMEN'S 

9336
05:57:11,360 --> 05:57:12,640
HEALTH RESEARCH AND CENTER 

9337
05:57:12,640 --> 05:57:15,320
COMMUNITIES THAT ARE MORE OFTEN 

9338
05:57:15,320 --> 05:57:16,720
BEARING THE BRUNT OF THE 

9339
05:57:16,720 --> 05:57:18,760
DISPARITIES WE ACTUALLY CAN 

9340
05:57:18,760 --> 05:57:20,240
TRANSLATE FASTER.

9341
05:57:20,240 --> 05:57:23,960
AND THE IMPLEMENTATION AND SCALE

9342
05:57:23,960 --> 05:57:25,280
ACTUALLY GOES A BIT BETTER.

9343
05:57:25,280 --> 05:57:27,560
THE EXAMPLE OF THE 

9344
05:57:27,560 --> 05:57:29,200
IMPLEMENTATION SCIENCE HUB RFA 

9345
05:57:29,200 --> 05:57:34,600
FOR THE IMPROVE INITIATIVE IS A 

9346
05:57:34,600 --> 05:57:36,600
WONDERFUL EXAMPLE OF PUTTING 

9347
05:57:36,600 --> 05:57:38,640
FUNDING ANNOUNCEMENTS OUT FOR 

9348
05:57:38,640 --> 05:57:40,240
CENTERS AND THEN HAVING NOT ONLY

9349
05:57:40,240 --> 05:57:44,160
A DATA SCIENCE HUB BUT ALSO AN 

9350
05:57:44,160 --> 05:57:45,120
IMPLEMENTATION DATA SCIENCE HUB 

9351
05:57:45,120 --> 05:57:47,320
TO SUPPORT THE CENTERS.

9352
05:57:47,320 --> 05:57:50,280
THAT'S A GREAT EXAMPLE AND I 

9353
05:57:50,280 --> 05:57:52,120
APPRECIATE YOUR LEADERSHIP, 

9354
05:57:52,120 --> 05:57:55,960
DR. CLAYTON AND TEAM, ORWH TEAM 

9355
05:57:55,960 --> 05:57:56,840
FOR THINKING OF THAT AND DOING 

9356
05:57:56,840 --> 05:57:57,880
THAT.

9357
05:57:57,880 --> 05:58:00,800
SO THANK YOU.

9358
05:58:00,800 --> 05:58:01,320
>>THANK YOU.

9359
05:58:01,320 --> 05:58:04,640
WE CAN'T TAKE ALL THE CREDIT FOR

9360
05:58:04,640 --> 05:58:05,040
THAT.

9361
05:58:05,040 --> 05:58:07,720
NHLBI HAS A MATERNAL HEALTH 

9362
05:58:07,720 --> 05:58:09,680
COMMUNITY IMPLEMENTATION 

9363
05:58:09,680 --> 05:58:09,920
PROGRAM.

9364
05:58:09,920 --> 05:58:11,800
I KNOW YOU KNOW ABOUT IT AND I 

9365
05:58:11,800 --> 05:58:13,640
WANT TO SHARE THAT WITH THE 

9366
05:58:13,640 --> 05:58:15,000
GROUP THOUGH AND THRILLED WE 

9367
05:58:15,000 --> 05:58:16,640
WERE ABLE TO SUPPORT TWO OF 

9368
05:58:16,640 --> 05:58:20,000
THOSE PROGRAMS TO EXPAND THEIR 

9369
05:58:20,000 --> 05:58:21,880
REACH THIS FISCAL YEAR TO TWO 

9370
05:58:21,880 --> 05:58:23,480
STATES IN THE SOUTH.

9371
05:58:23,480 --> 05:58:27,080
SO WORKING ACROSS OUR PARTNERS 

9372
05:58:27,080 --> 05:58:29,640
WHEN THEY CREATE SOMETHING THAT 

9373
05:58:29,640 --> 05:58:32,600
CAN BE LEVERAGED TO ADDRESS WHAT

9374
05:58:32,600 --> 05:58:33,840
WE'VE IDENTIFIED ARE CRITICAL 

9375
05:58:33,840 --> 05:58:37,320
HEALTH NEEDS FOR WOMEN IS A 

9376
05:58:37,320 --> 05:58:39,120
STRATEGY AND WE'RE LOOKING 

9377
05:58:39,120 --> 05:58:40,360
FORWARD TO THE FEEDBACK ON THAT 

9378
05:58:40,360 --> 05:58:45,840
AND MOSTLY YOU COMMENTED ON 

9379
05:58:45,840 --> 05:58:47,640
STRUCTURAL FACTORS WHICH WE SAW 

9380
05:58:47,640 --> 05:58:49,520
PRESENTATIONS TODAY THAT SHOWED 

9381
05:58:49,520 --> 05:58:57,880
INCREASING THE GREEN CANOPY IN 

9382
05:58:57,880 --> 05:59:08,560
FORM -- IN FORMERLY RED LINED 

9383
05:59:08,560 --> 05:59:09,840
AREAS IS ACTIONABLE BY OUR 

9384
05:59:09,840 --> 05:59:11,200
COLLEAGUES AND OTHER 

9385
05:59:11,200 --> 05:59:12,600
STAKEHOLDERS IN THE SPACE.

9386
05:59:12,600 --> 05:59:18,840
WE REALIZE WE'RE NOT THE ONLY --

9387
05:59:18,840 --> 05:59:22,400
WE'RE A BIG PLAYER BUT NOT THE 

9388
05:59:22,400 --> 05:59:23,520
ONLY PLAYER IN THE SPACE BECAUSE

9389
05:59:23,520 --> 05:59:27,040
SO MANY THINGS AFFECT OUR 

9390
05:59:27,040 --> 05:59:27,280
HEALTH.

9391
05:59:27,280 --> 05:59:28,800
>>I'M IN THE PROCESS OF
PACKING

9392
05:59:28,800 --> 05:59:30,200
UP AFTER 16 YEARS AT THE 

9393
05:59:30,200 --> 05:59:31,600
UNIVERSITY OF MICHIGAN AND I 

9394
05:59:31,600 --> 05:59:33,520
DON'T KNOW IF YOU CAN SEE MY 

9395
05:59:33,520 --> 05:59:35,040
OFFICE AND THERE'S BOXES WHERE 

9396
05:59:35,040 --> 05:59:36,600
EVER AND A HAD OCCASION TO DIG 

9397
05:59:36,600 --> 05:59:38,720
THROUGH OLD FILES BECAUSE I'M A 

9398
05:59:38,720 --> 05:59:40,600
PACK RAT AND I PUT THESE ASIDE 

9399
05:59:40,600 --> 05:59:42,680
BECAUSE I THOUGHT YOU'D ENJOY 

9400
05:59:42,680 --> 05:59:44,720
THIS AS MUCH AS I DID.

9401
05:59:44,720 --> 05:59:46,840
I HAVE ALL THESE OLD PRESS 

9402
05:59:46,840 --> 05:59:49,760
RELEASES FROM THE EARLY 1990 AND

9403
05:59:49,760 --> 05:59:51,120
RESEARCH FOR MEN ONLY AND 

9404
05:59:51,120 --> 05:59:54,600
DOCTORS USE FOR TREAT WITH AND 

9405
05:59:54,600 --> 05:59:56,640
VIVIENNE PIN HAS BEEN CHOSEN TO 

9406
05:59:56,640 --> 05:59:58,760
HEAD THE OFFICE AT WOMEN'S 

9407
05:59:58,760 --> 06:00:02,280
HEALTH AND IT UNDER SCORES FOR 

9408
06:00:02,280 --> 06:00:04,440
ME WHEN I FEEL DAUNTED BY THE 

9409
06:00:04,440 --> 06:00:06,680
MAGNITUDE OF WHAT WE HAVE YET TO

9410
06:00:06,680 --> 06:00:09,880
ACCOMPLISH, IT GIVES ME A SENSE 

9411
06:00:09,880 --> 06:00:13,560
OF GRATITUDE TO BE WHERE WE ARE 

9412
06:00:13,560 --> 06:00:18,640
AND ACCOMPLISHMENT TO SEE HOW 

9413
06:00:18,640 --> 06:00:21,800
MUCH HAS BEEN STUDIED AND HOW 

9414
06:00:21,800 --> 06:00:27,040
MUCH MORE WE KNOW NOW THAN WE 

9415
06:00:27,040 --> 06:00:28,440
DID THEN AND JUST A PACK RAT AND

9416
06:00:28,440 --> 06:00:29,560
THIS IS FROM 1990s.

9417
06:00:29,560 --> 06:00:31,080
>>ABSOLUTELY.

9418
06:00:31,080 --> 06:00:33,680
IF YOU THINK ABOUT WHERE WE WERE

9419
06:00:33,680 --> 06:00:35,080
AND YOU'VE RIGHT, WE'VE COME A 

9420
06:00:35,080 --> 06:00:35,360
LONG WAY.

9421
06:00:35,360 --> 06:00:36,760
IT DOESN'T MEAN WE DON'T HAVE 

9422
06:00:36,760 --> 06:00:38,320
MORE TO GO BECAUSE THIS GROUP IS

9423
06:00:38,320 --> 06:00:42,800
EXTREMELY AWARE OF THE 

9424
06:00:42,800 --> 06:00:43,720
INCREDIBLE NEEDS OF ALL WOMEN 

9425
06:00:43,720 --> 06:00:45,600
ACROSS THE LIFE COURSE AND WE 

9426
06:00:45,600 --> 06:00:47,920
HEARD A TOUCH ON MENOPAUSE 

9427
06:00:47,920 --> 06:00:48,240
EARLIER.

9428
06:00:48,240 --> 06:00:49,360
DIDN'T HEAR MUCH MORE ABOUT THAT

9429
06:00:49,360 --> 06:00:51,840
BUT THAT'S REALLY IMPORTANT TO 

9430
06:00:51,840 --> 06:00:52,600
US AS WELL.

9431
06:00:52,600 --> 06:00:54,560
AND I DIDN'T KNOW IN THE LAST 

9432
06:00:54,560 --> 06:00:55,840
MINUTE WE HAVE ONE MINUTE, I DID

9433
06:00:55,840 --> 06:00:59,160
WANT TO GIVE DR. ANDERSON A 

9434
06:00:59,160 --> 06:01:01,600
MOMENT TO COMMENT ON WHETHER SHE

9435
06:01:01,600 --> 06:01:05,080
WANTED TO MAKE ANY REMARKS ABOUT

9436
06:01:05,080 --> 06:01:09,760
MENOPAUSE RESEARCH.

9437
06:01:09,760 --> 06:01:10,800
>>THANK YOU.

9438
06:01:10,800 --> 06:01:14,520
THAT'S A LOT OF WORK ON THE 

9439
06:01:14,520 --> 06:01:15,360
BIOLOGICAL EFFORT TO UNDERSTAND 

9440
06:01:15,360 --> 06:01:16,520
THE SYMPTOMS ASSOCIATED WITH IT 

9441
06:01:16,520 --> 06:01:18,560
AND TO REALLY HONE IN ON THE 

9442
06:01:18,560 --> 06:01:18,840
TREATMENT.

9443
06:01:18,840 --> 06:01:19,760
THERE'S A LOT OF CONFUSION ABOUT

9444
06:01:19,760 --> 06:01:24,200
WHAT THE RESULTS OF THE WOMEN'S 

9445
06:01:24,200 --> 06:01:25,600
CONFERENCE HAS PROVIDED AND 

9446
06:01:25,600 --> 06:01:27,840
RETRENCHMENT IN THE USE OF 

9447
06:01:27,840 --> 06:01:29,800
HORMONES AND I THINK WE NEED TO 

9448
06:01:29,800 --> 06:01:32,520
BETTER UNDERSTAND THIS AND SO I 

9449
06:01:32,520 --> 06:01:33,240
THINK ADDITIONAL RESEARCH EVEN 

9450
06:01:33,240 --> 06:01:36,600
ON HORMONE THERAPY ITSELF IS 

9451
06:01:36,600 --> 06:01:38,040
REALLY IMPORTANT.

9452
06:01:38,040 --> 06:01:39,880
>>THANK YOU SO MUCH, 

9453
06:01:39,880 --> 06:01:40,760
DR. ANDERSON.

9454
06:01:40,760 --> 06:01:43,240
DR. NOURSI, BEFORE WE CLOSE I'LL

9455
06:01:43,240 --> 06:01:44,800
MAKE SOME CLOSING REMARKS IF 

9456
06:01:44,800 --> 06:01:46,280
THAT'S OKAY IN A MINUTE BUT 

9457
06:01:46,280 --> 06:01:48,160
BEFORE WE CLOSE I JUST WANT TO 

9458
06:01:48,160 --> 06:01:50,840
THANK ALL THE AMAZING PRESENTERS

9459
06:01:50,840 --> 06:01:53,720
WHO ARE PARTICIPATING IN TODAY'S

9460
06:01:53,720 --> 06:01:54,360
MEET.

9461
06:01:54,360 --> 06:01:57,840
WE REALLY APPRECIATE DEEPLY THE 

9462
06:01:57,840 --> 06:02:02,800
SUPPORT THAT WE HAVE AND FOR THE

9463
06:02:02,800 --> 06:02:06,840
ORWH MEMBERS GIVE TO US IN 

9464
06:02:06,840 --> 06:02:09,240
RESPONDING TO OUR QUERIES, 

9465
06:02:09,240 --> 06:02:10,040
WEIGHING IN ON INFORMATION WE 

9466
06:02:10,040 --> 06:02:13,360
ASK YOU TO TALK ABOUT AND I WANT

9467
06:02:13,360 --> 06:02:15,880
TO THANK THE SCIENCE POLICY 

9468
06:02:15,880 --> 06:02:17,640
PLANNING AND ANALYSIS SECTION 

9469
06:02:17,640 --> 06:02:19,680
THAT LEADS THE ACRWH AND 

9470
06:02:19,680 --> 06:02:24,120
DR. NOURSI WITH THE FEARLESS 

9471
06:02:24,120 --> 06:02:27,280
EXEC SEC I ASKED HER TO SUB FOR 

9472
06:02:27,280 --> 06:02:29,600
THIS LIKE OVER A YEAR AND A HALF

9473
06:02:29,600 --> 06:02:39,680
AGO.

9474
06:02:42,360 --> 06:02:44,520
HE'S TAKEN US TO THE NEXT LEVEL.

9475
06:02:44,520 --> 06:02:46,680
THANK YOU FOR YOUR LEADERSHIP IN

9476
06:02:46,680 --> 06:02:48,040
THAT SPACE.

9477
06:02:48,040 --> 06:02:49,240
EVERY AT TEAM ORWH THERE'S A LOT

9478
06:02:49,240 --> 06:02:51,840
OF WORK THAT HAPPENS BEHIND THE 

9479
06:02:51,840 --> 06:02:53,120
SCENES TO DO THE ANALYSIS AND 

9480
06:02:53,120 --> 06:02:55,920
GET THE INFORMATION TO YOU IN A 

9481
06:02:55,920 --> 06:02:58,680
TIMELY MANNER.

9482
06:02:58,680 --> 06:02:59,760
THANK YOU.

9483
06:02:59,760 --> 06:03:03,720
SARAH HELMAN IS HER RIGHT HAND 

9484
06:03:03,720 --> 06:03:06,800
ON ALL THINGS TEAM ORWH AND 

9485
06:03:06,800 --> 06:03:08,200
THANK YOU ALL AND OUR FOLKS WHO 

9486
06:03:08,200 --> 06:03:11,040
MAKE SURE WE LOOK GOOD WHEN WE 

9487
06:03:11,040 --> 06:03:13,160
ARE OUT HERE CHAMPIONING WOMEN'S

9488
06:03:13,160 --> 06:03:15,240
HEALTH, FIGHTING THE GOOD FIGHT 

9489
06:03:15,240 --> 06:03:18,880
FOR ALL WOMEN AND SO I WILL END 

9490
06:03:18,880 --> 06:03:22,120
WITH AN INTEGRATING WAY TO THINK

9491
06:03:22,120 --> 06:03:24,600
ABOUT THE HEALTH OF WOMEN.

9492
06:03:24,600 --> 06:03:25,720
SO YOU'VE SEEN OUR 

9493
06:03:25,720 --> 06:03:29,520
MULTI-DIMENSIONAL FRAMEWORK 

9494
06:03:29,520 --> 06:03:30,960
WHICH HAS THE LIFE COURSE AND 

9495
06:03:30,960 --> 06:03:32,120
EVERYTHING THAT HAPPENED BEFORE 

9496
06:03:32,120 --> 06:03:34,960
CAN AFFECT THE HEALTH OF A WOMAN

9497
06:03:34,960 --> 06:03:36,920
TODAY EVEN IN UTERO.

9498
06:03:36,920 --> 06:03:38,960
YOU HEARD PREFERENCES TO 

9499
06:03:38,960 --> 06:03:42,200
EPIGENETIC MODIFICATION AND 

9500
06:03:42,200 --> 06:03:43,880
INTERNAL FACTORS LIKE SEX AND 

9501
06:03:43,880 --> 06:03:46,960
GENETIC ANCESTRY AND EXTERNAL 

9502
06:03:46,960 --> 06:03:48,440
FACTORS LIKE THE ENVIRONMENT WE 

9503
06:03:48,440 --> 06:03:51,440
LIVE IN WHETHER IT'S A TOXIC 

9504
06:03:51,440 --> 06:03:55,080
EXPOSURE, HAIR DYE, OR A TOXIC 

9505
06:03:55,080 --> 06:03:56,200
RELATIONSHIP WITH A WOMAN BEING 

9506
06:03:56,200 --> 06:03:59,560
AT THE HIGHEST RISK OF INTIMATE 

9507
06:03:59,560 --> 06:04:02,120
PARTNER VIOLENCE IN HER LIFE 

9508
06:04:02,120 --> 06:04:03,160
WHEN SHE'S PREGNANT.

9509
06:04:03,160 --> 06:04:05,120
A PERSON WHO IS PREGNANT IS THE 

9510
06:04:05,120 --> 06:04:08,600
HIGHEST RISK IN YOUR LIFE OF 

9511
06:04:08,600 --> 06:04:09,160
INTIMATE PARTNER VIOLENCE.

9512
06:04:09,160 --> 06:04:12,560
SO INTERNAL FACTORS, EXTERNAL 

9513
06:04:12,560 --> 06:04:14,120
FACTORS, EVERYTHING THAT 

9514
06:04:14,120 --> 06:04:15,400
HAPPENED BEFORE YOUR LIFE 

9515
06:04:15,400 --> 06:04:19,080
COURSE, YOUR TRAJECTORY, YOUR 

9516
06:04:19,080 --> 06:04:20,240
INTERACTION BETWEEN YOUR GENES 

9517
06:04:20,240 --> 06:04:21,640
AND THE ENVIRONMENT, THE 

9518
06:04:21,640 --> 06:04:22,640
POLICIES AROUND YOU AND WHERE 

9519
06:04:22,640 --> 06:04:23,920
YOU, WHAT YOU HAVE ACCESS TO AND

9520
06:04:23,920 --> 06:04:28,680
WHAT YOU DO NOT HAVE ACCESS TO.

9521
06:04:28,680 --> 06:04:31,280
AND YOUR ENTIRE TRAJECTORY OF 

9522
06:04:31,280 --> 06:04:33,840
YOUR LIFE COURSE WHETHER YOU'RE 

9523
06:04:33,840 --> 06:04:35,160
PARTICIPATING IN THE LABOR 

9524
06:04:35,160 --> 06:04:37,120
WORKFORCE, WHETHER YOU HAVE LEFT

9525
06:04:37,120 --> 06:04:39,640
THE LABOR WORKFORCE BECAUSE YOU 

9526
06:04:39,640 --> 06:04:42,160
EXPERIENCED SEXUAL HARASSMENT OR

9527
06:04:42,160 --> 06:04:42,560
TRAUMA.

9528
06:04:42,560 --> 06:04:45,720
WE KNOW IT'S HAPPENING MORE AND 

9529
06:04:45,720 --> 06:04:47,200
MORE.

9530
06:04:47,200 --> 06:04:49,200
ALL THOSE ARE OUR CONCERNS AND 

9531
06:04:49,200 --> 06:04:51,440
THE STRATEGY WE'VE USED TO TRY 

9532
06:04:51,440 --> 06:04:52,040
TO BE ABLE TO IMPROVE THAT 

9533
06:04:52,040 --> 06:04:53,560
THROUGH THE RESEARCH CONTINUUM 

9534
06:04:53,560 --> 06:04:57,600
IS TO INTENTIONALLY INTEGRATE 

9535
06:04:57,600 --> 06:05:00,600
CONSIDERATIONS OF SEX AS A 

9536
06:05:00,600 --> 06:05:01,800
BIOLOGICAL VARIABLE FROM THE 

9537
06:05:01,800 --> 06:05:05,520
MOST BASIC STUDIES WHERE WE WERE

9538
06:05:05,520 --> 06:05:09,280
EXPLORING A BIOLOGIC PHENOMENON 

9539
06:05:09,280 --> 06:05:10,920
THROUGH THAT PRE-CLINICAL WORK 

9540
06:05:10,920 --> 06:05:12,760
GOING INTO AN ANIMAL MODEL WHICH

9541
06:05:12,760 --> 06:05:15,160
IS MODELLING HUMAN DISEASE THAT 

9542
06:05:15,160 --> 06:05:17,200
AFFECTS MEN AND WOMEN PERHAPS OR

9543
06:05:17,200 --> 06:05:20,080
AFFECTS FEMALES ONLY TO CONSIDER

9544
06:05:20,080 --> 06:05:21,960
SEX VERY INTENTIONALLY AS WE 

9545
06:05:21,960 --> 06:05:24,440
SELECT OUR RESEARCH QUESTION AS 

9546
06:05:24,440 --> 06:05:27,840
WE DESIGN OUR EXPERIMENTS AND 

9547
06:05:27,840 --> 06:05:31,960
USE FACTORIAL DESIGN TO GET 

9548
06:05:31,960 --> 06:05:34,840
INFORMATION THAT SEX IS 

9549
06:05:34,840 --> 06:05:36,000
DISAGGREGATED OR RELEVANT OR NOT

9550
06:05:36,000 --> 06:05:38,960
AND AS WE GO FIRST IN HUMAN AND 

9551
06:05:38,960 --> 06:05:40,840
WHAT THAT MIGHT MEAN IN TERMS OF

9552
06:05:40,840 --> 06:05:43,920
DIFFERENT DOSAGES AND LIKELIHOOD

9553
06:05:43,920 --> 06:05:46,280
OF ADVERSE AFFECTS WHETHER 

9554
06:05:46,280 --> 06:05:48,720
THAT'S A NEW IMMUNIZATION OR A 

9555
06:05:48,720 --> 06:05:51,320
NEW COMPOUND THAT IS WORKING ON 

9556
06:05:51,320 --> 06:05:52,400
A NEW TARGET.

9557
06:05:52,400 --> 06:05:56,440
SO THROUGH THAT TRANSLATION AND 

9558
06:05:56,440 --> 06:06:00,480
THE GENDERED AFFECTS THAT ALL 

9559
06:06:00,480 --> 06:06:01,000
AFFECT OUR HEALTH TODAY.

9560
06:06:01,000 --> 06:06:03,080
SO IF WE CAN INTEGRATE 

9561
06:06:03,080 --> 06:06:05,400
CONSIDERATIONS OF SEX AND GENDER

9562
06:06:05,400 --> 06:06:07,400
ON THAT BASIC PRE CLINICAL, 

9563
06:06:07,400 --> 06:06:11,960
TRANSLATIONAL APPLIES 

9564
06:06:11,960 --> 06:06:13,080
IMPLEMENTATION, EDUCATION, 

9565
06:06:13,080 --> 06:06:15,080
EVERYONE IN THE SPACE, 

9566
06:06:15,080 --> 06:06:16,840
DR. JOHNSON THE ORAL HEALTH AND 

9567
06:06:16,840 --> 06:06:17,200
DENTISTS.

9568
06:06:17,200 --> 06:06:18,600
WE DIDN'T GET TO THAT MENTION 

9569
06:06:18,600 --> 06:06:20,080
THAT BUT ORAL HEALTH IS AN 

9570
06:06:20,080 --> 06:06:22,680
IMPORTANT PART OF HEALTH.

9571
06:06:22,680 --> 06:06:23,960
MENTAL HEALTH IS A PART OF 

9572
06:06:23,960 --> 06:06:24,400
HEALTH.

9573
06:06:24,400 --> 06:06:28,240
IF WE CAN DO THAT AND INFORM 

9574
06:06:28,240 --> 06:06:32,560
POLICIES AND INFORM PRACTICES, 

9575
06:06:32,560 --> 06:06:33,880
INFORM HOW HEALTH CARE'S 

9576
06:06:33,880 --> 06:06:34,680
DELIVERED IN THE FUTURE AND GO 

9577
06:06:34,680 --> 06:06:37,240
BACK AND START AGAIN WE MAY BE 

9578
06:06:37,240 --> 06:06:38,560
ABLE TO INFORM AND IMPROVE THE 

9579
06:06:38,560 --> 06:06:39,320
HEALTH OF ALL WOMEN.

9580
06:06:39,320 --> 06:06:42,080
SO THAT IS THE INTEGRATING 

9581
06:06:42,080 --> 06:06:44,480
FRAMEWORK THAT I USE TO APPROACH

9582
06:06:44,480 --> 06:06:47,400
THE WORK THAT WE DO AND TO SHOW 

9583
06:06:47,400 --> 06:06:49,120
EVERYONE THAT THERE'S A PLACE 

9584
06:06:49,120 --> 06:06:52,600
FOR YOU HERE THAT WE PROMOTE 

9585
06:06:52,600 --> 06:06:55,480
INNOVATION AND PROMOTE EQUITY 

9586
06:06:55,480 --> 06:06:57,040
AND PROMOTE RIGOR WHEN WE 

9587
06:06:57,040 --> 06:07:01,040
CONSIDER SEX AND GENDER THE 

9588
06:07:01,040 --> 06:07:05,720
BIOMEDICAL RESEARCH CONTINUUM 

9589
06:07:05,720 --> 06:07:07,320
AND WE'RE HERE TO INFORM AND 

9590
06:07:07,320 --> 06:07:09,880
IMPROVE THE HEALTH OF WOMEN AND 

9591
06:07:09,880 --> 06:07:12,240
WHY WE'RE HERE AND WOMEN WERE 

9592
06:07:12,240 --> 06:07:13,600
NOT INCLUDED.

9593
06:07:13,600 --> 06:07:16,280
THE FINDINGS FOR MEN WERE 

9594
06:07:16,280 --> 06:07:17,080
APPLIED TO WOMEN.

9595
06:07:17,080 --> 06:07:18,160
CERTAINLY THAT'S NOT RIGOROUS.

9596
06:07:18,160 --> 06:07:19,280
THERE WAS A DIFFERENT 

9597
06:07:19,280 --> 06:07:20,040
UNDERSTANDING.

9598
06:07:20,040 --> 06:07:21,520
WE KNOW BETTER NOW SO WE CAN DO 

9599
06:07:21,520 --> 06:07:22,080
THINGS BETTER.

9600
06:07:22,080 --> 06:07:25,360
WE HAVE EVOLVING SENSE OF WHAT 

9601
06:07:25,360 --> 06:07:28,200
SEX AND GENDER ARE, HOW THEY'RE 

9602
06:07:28,200 --> 06:07:30,360
RELATED TO EACH OTHER AND HOW 

9603
06:07:30,360 --> 06:07:33,640
THEY'RE EACH IMPORTANT EXTERNAL 

9604
06:07:33,640 --> 06:07:35,320
AND INTERNAL FACTOR IMPORTANT 

9605
06:07:35,320 --> 06:07:37,720
AND NEED TO CONSIDER UNDER 

9606
06:07:37,720 --> 06:07:40,440
SERVED, UNDER STUDIED WOMEN IN 

9607
06:07:40,440 --> 06:07:42,400
EVERYTHING WE DO AND HOW 

9608
06:07:42,400 --> 06:07:45,880
IMPROVING HEALTH FOR THOSE WHO 

9609
06:07:45,880 --> 06:07:47,880
NEED IT MOST WILL IMPROVE HEALTH

9610
06:07:47,880 --> 06:07:51,080
OF EVERYONE AND DR. SIMON HOW AS

9611
06:07:51,080 --> 06:07:55,120
WOMEN MAKING 80% OF HEALTH 

9612
06:07:55,120 --> 06:07:58,960
DECISIONS THE ECONOMIC IMPACT OF

9613
06:07:58,960 --> 06:08:00,600
THE HEALTH OF WOMEN, THE 

9614
06:08:00,600 --> 06:08:02,320
SOCIETAL IMPACT WILL IMPROVE THE

9615
06:08:02,320 --> 06:08:04,800
FAMILY AND WILL IMPROVE THE 

9616
06:08:04,800 --> 06:08:07,200
LABOR PARTICIPATION AND 

9617
06:08:07,200 --> 06:08:08,440
EDUCATION AND IMPROVE EVERYONE'S

9618
06:08:08,440 --> 06:08:08,680
HEALTH.

9619
06:08:08,680 --> 06:08:10,680
THE DATA IS WELL DOCUMENTED 

9620
06:08:10,680 --> 06:08:13,200
INVESTING IN WOMEN'S HEALTH IS A

9621
06:08:13,200 --> 06:08:15,640
SMART INVESTMENT FOR SOCIETY.

9622
06:08:15,640 --> 06:08:17,040
SO THANK YOU ALL FROM THE BOTTOM

9623
06:08:17,040 --> 06:08:20,600
OF MY HEART FOR YOUR COMMITMENT,

9624
06:08:20,600 --> 06:08:21,840
CONTINUED COMMITMENT TO WOMEN'S 

9625
06:08:21,840 --> 06:08:22,080
HEALTH.

9626
06:08:22,080 --> 06:08:24,480
WE NEED YOU AND WOMEN NEED YOU 

9627
06:08:24,480 --> 06:08:25,920
AND WE'RE DELIGHTED TO HAVE YOU 

9628
06:08:25,920 --> 06:08:28,400
ON OUR TEAM AND YOUR ADVICE AND 

9629
06:08:28,400 --> 06:08:29,000
COUNCIL AND THIS ADVISORY 

9630
06:08:29,000 --> 06:08:30,640
COMMITTEE ARE SUPER IMPORTANT TO

9631
06:08:30,640 --> 06:08:33,880
THE FUTURE AND I WANT TO AGAIN 

9632
06:08:33,880 --> 06:08:36,040
THANK TEAM ORWH FOR ALL YOU'VE 

9633
06:08:36,040 --> 06:08:38,640
DONE AND OUR PARTNERS AND 

9634
06:08:38,640 --> 06:08:39,200
COLLABORATORS ACROSS THE 

9635
06:08:39,200 --> 06:08:40,280
RESEARCH ECO SYSTEM.

9636
06:08:40,280 --> 06:08:41,880
WE'VE GOT A LOT OF WORK TO DO 

9637
06:08:41,880 --> 06:08:44,000
BUT WE ARE UP FOR THE CHALLENGE 

9638
06:08:44,000 --> 06:08:44,400
REGARDLESS.

9639
06:08:44,400 --> 06:08:47,040
WE'RE UP FOR THE CHALLENGE AND 

9640
06:08:47,040 --> 06:08:48,320
WE'LL BE THERE SO THANK YOU VERY

9641
06:08:48,320 --> 06:08:50,520
MUCH FOR YOUR ASSISTANCE AND 

9642
06:08:50,520 --> 06:08:50,840
YOUR SUPPORT.

9643
06:08:50,840 --> 06:08:52,120
WE ARE ADJOURNED.

9644
06:08:52,120 --> 06:08:55,680
THANK YOU, DR. NOURSI.

9645
06:08:55,680 --> 00:00:00,000
>>BYE, EVERYBODY.