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>> Joshua Gordon: WELCOME
TO

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THE 270th MEETING OF THE

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NATIONAL ADVISORY MENTAL HEALTH

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COUNCIL.

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I'M JOSHUA GORD AN AND I'D LIKE

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TO THANK YOU FOR JOINING OUR

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MEETING TODAY.

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EMBRACING OUR HYBRID FORMAT.

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I'M JOINING YOU VIRTUALLY TODAY

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FOR THE FIRST PART OF OUR

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MEETING BUT WILL COME IN-PERSON

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AFTER THE BREAK LATER THIS

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AFTERNOON DUE TO AN EVENT HERE

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ON CAMPUS THAT I NEED TO ATTEND.

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OUR COUNCIL MEETING IS A TIME

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FOR INFORMATION EXCHANGE BETWEEN

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INSTITUTE STAFF AND COUNCIL

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MEMBERS.

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AS WELL AS AN OPPORTUNITY FOR

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THE COUNCIL PROVIDE FEEDBACK TO

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THE NATIONAL INSTITUTE OF MENTAL

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HEALTH.

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IT'S ALSO AN OPPORTUNITY FOR US

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TO DISCUSS IN FRONT OF THE

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PUBLIC THE MATTERS REGARDING

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PRIORITIES AND POLICIES AT NIMH

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THAT ARE IMPORTANT TO TALK

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ABOUT.

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WE HAVE A FULL SCHEDULE.

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THANK YOU FOR PARTICIPATING IN

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THIS MEETING.

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BEFORE WE MOVE ON IT THE

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BUSINESS OF THE MEETING, I'LL

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TAKE A MOMENT TO REMIND YOU OF A

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FEW LOGISTICAL ITEMS.

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AS ALWAYS, NOT THIS OPEN SESSION

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IS BEING VIDEO CAST BROADLY TO

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THE NIH COMMUNITY AND TO THE

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VIEWING PUBLIC.

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ALLOWING PEOPLE TO WATCH AND

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LISTEN REMOTELY.

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THE MEETING IS ALSO BEING

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RECORDED TO ALLOW VIEWING ON

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DEMAND AT A LATER DATE.

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WE ENCOURAGE COUNCIL MEMBERS

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BOTH IN THE ROOM AND REMOTE TO

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KEEP YOUR VIDEO ON THROUGHOUT

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THE MEETING, SO THAT YOU CAN BE

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SEEN BY THOSE OUTSIDE OF THE

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ROOM.

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HOWEVER, WE ASK THAT NIMH STAFF

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INCLUDING DIVISION DIRECTORS USE

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VIDEO ONLY WHEN PRESENTING.

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FOR COUNCIL MEMBERS IN THE ROOM,

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PLEASE USE THE MICS ON THE

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TABLE.

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ALWAYS PUSH THE ON BUTTON WHEN

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YOU SPEAK AND OFF WHEN YOU ARE

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DONE.

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DO NOT TURN ON THE AUDIO FOR

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YOUR COMPUTER, THE MICROPHONE IS

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ON THE TABLE WILL PROVIDE THE

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AUDIO FOR YOU.

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FOR REMOTE COUNCIL MEMBERS,

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UNMUTE YOUR MICROPHONE WHEN

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SPEAKING AND PLEASE MUTE YOUR

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MICROPHONE WHEN YOU ARE NOT.

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FOR THOSE REMOTE MEMBERS WHO

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MIGHT BE USING PHONE AUDIO, YOU

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CAN PRESS STAR 6 TO MUTE AND

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UNMUTE.

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WE ASK COUNCIL MEMBERS TO UNMUTE

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TO MAKE A COMMENT OR ASK A

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QUESTION RATHER THAN USING THE

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ZOOM AND CHAT FUNCTION.

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PLEASE RESERVE CHAT USE FOR

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CONTACTING NIMH ZOOM HOSTS WITH

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ANY TECHNICAL ISSUES.

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I WANT TO REMIND YOU THAT

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EVERYTHING ENTERED INTO THE

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CHATBOX, WILL BE INCLUDED IN THE

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PERMANENT RECORD OF THE SESSION,

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EVEN SIDE BAR CHATS TO OTHER

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MEMBERS OF THE COUNCIL OR TO

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STAFF WILL BE PART OF THIS

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RECORD AND WILL BE PUBLICLY

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AVAILABLE.

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WHEN WE CALL FOR A VOTE, WE WILL

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ASK ALL COUNCIL MEMBERS TO USE

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THE RAISE-HAND FUNCTION IN ZOOM.

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IT MIGHT BE LOCATED IN THE ZOOM

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PARTICIPANT MENU OR THE BOTTOM

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UNDER THE REACTIONS MENU

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DEPENDING ON YOUR PARTICULAR

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VERSION.

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VOTING COUNCIL MEMBERS ON THE

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PHONE SHOULD UNMUTE BY PRESSING

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STAR 6 AND VOTE BY VOICE.

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IF YOU EXPERIENCE CONDUCTIVITY

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ISSUES AND YOU NEED TO CALL IN,

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PLEASE REFER TO YOUR PERSONAL

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ZOOM ITINERARY FOR THE OPEN

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SESSION DETAILS.

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WITH THAT, I'M GOING TO TURN IT

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OVER TO TRACY WHO WILL SEE

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COMMENTS AND CORRECTIONS TO THE

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MINUTES AND CONDUCT A VOTE AND

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THEN MOVE ONTO THE NEXT ITEM ON

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OUR AGENDA.

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THOSE OF YOU WHO ARE HOPING FOR

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IT, I WILL BE GIVING THE FULL

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REGULAR DIRECTORS REPORT

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IMMEDIATELY AFTER THE BREAK AT

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AROUND 2:30.

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TRACY --

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>>THANK YOU.

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I'M SEEKING A MOTION FOR

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APPROVAL OF OUR 2023 MINUTES

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THAT THE COUNCIL MEMBERS HAD

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ACCESS TO IN THE ASR IN ADVANCE

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OF TODAY'S MEETING.

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DO I HAVE A MOTION OF APPROVAL?

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THANK YOU.

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AND A SECOND.

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OKAY.

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GREAT.

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ALL THOSE IN FAVOR OF APPROVING

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THE MINUTES, PLEASE USE YOUR

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RAISE-HAND FEATURE ON THE ZOOM.

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PERFECT.

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ALL RIGHT.

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ALL THOSE OPPOSED.

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ANY OPPOSED?

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ALL RIGHT.

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AND ANY ABSTENTIONS?

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OUR MINUTES ARE ALL SET.

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THANK YOU.

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AND WE'LL TURN IT OVER TO SHELLY

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TO GET US STARTED WITH CONCEPTS.

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>>Shelly: GOOD MORNING,
THANK

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YOU FOR BEING ON THE ZOOM.

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SO, AS JOSH ALLUDED TO WE'RE

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GOING TO BE FLIPPING THE ORDER

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AND WE'RE GOING TO START WITH

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CONCEPT CLEARANCES.

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TODAY YOU WILL HEAR ABOUT FUTURE

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INITIATIVES BEFORE JOSH'S

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DIRECTORS REPORT AND KEEP IN

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MIND OUR CONCEPT CLEARANCES ARE

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PRESENTED FOR EARLY FEEDBACK ON

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THESE FUTURE RESEARCH DIRECTIONS

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AND INCLUDING SUGGESTIONS TO

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HELP SHAPE THESE POTENTIAL

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INITIATIVES AS WE DEVELOP THEM.

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OUR CONCEPT PRESENTATIONS ARE

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INTENTIONALLY GENERAL AS WE ARE

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IN THE VERY EARLY SEASONS OF

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FORMULATING THESE SCIENTIFIC

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CONCEPTS INTO POTENTIAL FUND

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INITIATIVES.

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OUR DESCRIPTIONS OF EACH

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CONCEPTS WERE MADE AVAILABLE TO

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YOU VIA THE ASR WITH YOUR

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FEEDBACK AND NIH AIMS TO PROCEED

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WITH THE RESEARCH ACTIVITY,

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HOWEVER, THE PUB WILL INDICATION

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AND TIMING URN CERTAIN AND

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DEPENDING ON FUNDS BEING

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AVAILABLE.

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ONCE PRESENTED AT COUNCIL,

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CONCEPTS ARE POSTED ON THE NIMH

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WEBSITE AND AVAILABLE FOR

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FURTHER COMMENT.

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FOR THE PURPOSE OF TODAY'S

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DISCUSSION, WE HAVE ASSIGNED TWO

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COUNCIL MEMBERS FOR EACH CONCEPT

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THOUGH WE WELCOME FEEDBACK FROM

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ALL OF YOU.

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SO, WE'RE GOING TO GET STARTED

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WITH Dr. BOB HEINSEEN.

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>>Robert Heinssen: THANK
YOU

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VERY MUCH 12 THANK YOU FOR THE

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PENT TO RESERVE LEARNING IMPROVE

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MENTAL HEALTH SERVICES AND

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TREATMENT.

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IMPLEMENTATION RESEARCH IS

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DOCUMENTED BETWEEN SCIENTIFIC

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DISCOVERY AND TRANSLATION

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FINDINGS INTO RETAIN CLINICAL

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PRACTICE.

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MORE OVER, THE EFFECTIVENESS OF

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RESEARCH-BASED TREATMENT OFTEN

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DECLINES IN REAL WORLD CLINICAL

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SETTINGS IMPLEMENTATION

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SCIENTISTS WITH THIS PHENOMENON

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VOLTAGE DROP.

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HEALTHCARE WAS FIRST DESCRIBED

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BY THE INSTITUTE OF MEDICINE IN

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2007 AND AS A DATA DRIVEN

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FRAMEWORK FOR MITIGATING THIS

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DIMINISHMENT AND IMPROVING THE

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QUALITY AND EFFECTIVENESS OF

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EVIDENCE BASED SERVICES.

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TO DO SO, LEARNING HEALTH

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SYSTEMS INTEGRATE DATA

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COLLECTION AND ANALYSIS INTO

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CARE AND EMPLOY QUALITY

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MANAGEMENT STRATEGIES TO

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OPTIMIZE SERVICES AND PROVIDE

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REAL-TIME FEEDBACK TO CLINICIANS

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TO DRIVE IN PATIENT OUTCOMES AND

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HEALTHCARE DELIVERY.

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THESE CHARTS ILLUSTRATE RECENT

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PROGRESS IN TWO FEDERALLY FUNDED

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PROGRAMS THAT EMPHASIZE

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EVIDENCE-BASED PRACTICES FOR

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MENTAL DISORDERS.

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ON THE LEFT IT ILLUSTRATES RAPID

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GROWTH AND SUPPORTS PROGRAMS

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THAT PROVIDE COORDINATED

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SPECIALTY CARE.

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A RESEARCH-BASED INTERVENTION

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FOR FIRST EPISODES LIKE NOT

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HOSES.

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CHAT ON THE RIGHT REVEALS

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SIMILAR GROWTH IN THE NUMBER OF

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CERTIFIED COMMUNITY BEHAVIORAL

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HEALTH CLINICS.

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THESE CLINICS ARE EXPECTED TO

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PROVIDE EVIDENCE-BASED PRACTICES

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THAT MEET THE NEEDS OF CHILDREN,

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YOUTH AND ADULTS WITH COMPLEX

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MENTAL HEALTH AND SUBSTANCE USE

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DISORDERS.

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LEARNING HEALTHCARE METHODS CAN

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BE TEST  TESTED, REFINED AND EXD

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IN OUT PATIENT CLINICS SUCH AS

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THESE.

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EITHER IN SINGLE SITE OR

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RESEARCH NETWORK PROJECTS.

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FUTURE RESEARCH CAN BUILD UPON

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LESSONS LEARNED FROM EXISTING

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INITIATIVES.

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SUCH AS THE NIMH EARLY PSYCHOSIS

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2 WILL PROMOTE RESEARCH DATA

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SCIENCE AND EFFECTIVENESS AND

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SERVICES RESEARCH TO CREATE

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BETTER KNOWLEDGE AND TOOLS FOR

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DELIVERING AND ON TA MISSING

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EVIDENCE-BASED MENTAL HEALTH

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SERVICES.

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THE CONCEPT ALIGNS WITH

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EFFECTIVENESS RESEARCH,

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IMPLEMENTATION SCIENCE, AND

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HEATH EQUITY GOALS OUTLINED IN

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THE PLAN FOR RESEARCH AND ARE

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RECENT WHITE HOUSE REPORT ON

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MENTAL HEALTH RESEARCH

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PRIORITIES.

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THIS SLIDE HAVE AREAS CONSIDERED

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UNDER THIS CONCEPT AND WE

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ENVISION STAKEHOLDER ENGAGE

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RESEARCH THAT WILL LEVERAGE

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CLINICAL PRACTICE DATA INTO

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ACTION AND IMPLEMENT LEARNING

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HEALTHCARE METHODOLOGY TO

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00:09:14,960 --> 00:09:16,120
IMPROVE PREVENTATIVE AND

268
00:09:16,120 --> 00:09:18,600
TREATMENT INTERVENTIONS FOR

269
00:09:18,600 --> 00:09:19,160
PERSONS WITH MENTAL HEALTH.

270
00:09:19,160 --> 00:09:20,200
THANK YOU ALL FOR YOUR ATTENTION

271
00:09:20,200 --> 00:09:22,120
AND I LOOK FORWARD TO THE

272
00:09:22,120 --> 00:09:23,920
DISCUSSION AND QUESTIONS FROM

273
00:09:23,920 --> 00:09:26,240
COUNCIL.

274
00:09:26,240 --> 00:09:28,360
I BELIEVE WE HAVE Dr. KILBORN

275
00:09:28,360 --> 00:09:32,880
AND TELLFAIR HAVE AGREED TO

276
00:09:32,880 --> 00:09:36,200
DISCUSS AND Dr. TELLFAIR, YOU

277
00:09:36,200 --> 00:09:43,520
ARE IN THE ROOM.

278
00:09:43,520 --> 00:09:45,280
>>IT CAUGHT ME OFF GUARD
WITH

279
00:09:45,280 --> 00:09:46,320
THE OUT OF ORDER.

280
00:09:46,320 --> 00:09:50,520
SO, NO, IN REVIEWING THIS, I WAS

281
00:09:50,520 --> 00:09:53,040
APPRECIATIVE OF THE IDEA AND THE

282
00:09:53,040 --> 00:09:53,560
CONCEPT.

283
00:09:53,560 --> 00:09:55,680
IT WAS WRITTEN BROADLY BUT IT'S

284
00:09:55,680 --> 00:09:57,160
STILL VERY BROAD TO ME.

285
00:09:57,160 --> 00:09:59,880
IN TERMS OF FESS PHYSICAL TEE SO

286
00:09:59,880 --> 00:10:02,400
MY COMMENTS, WHILE I AGREE THAT

287
00:10:02,400 --> 00:10:03,760
WE SHOULD MOVE FORWARD WITH THIS

288
00:10:03,760 --> 00:10:05,760
HAVE TO DO WITH SPECIFICITY SO I

289
00:10:05,760 --> 00:10:08,040
WILL LEAVE IT AT THAT. THE FIRST

290
00:10:08,040 --> 00:10:09,160
PART OF THE QUESTION IS THAT I

291
00:10:09,160 --> 00:10:12,960
WOULD BE REALLY HELPFUL IN THIS

292
00:10:12,960 --> 00:10:15,600
SCOPE THAT YOU IDENTIFY WHO THE

293
00:10:15,600 --> 00:10:16,240
RESEARCHERS MIGHT BE WHO WOULD

294
00:10:16,240 --> 00:10:18,040
BEST BENEFIT FROM THIS WORK.

295
00:10:18,040 --> 00:10:19,440
AND AT WHAT LEVEL THEY MIGHT BE

296
00:10:19,440 --> 00:10:20,640
IN TERMS OF THE BENEFIT OF THE

297
00:10:20,640 --> 00:10:23,120
WORK BECAUSE I CAN SEE PERSONS

298
00:10:23,120 --> 00:10:25,200
BEING VERY ADVANCED AND I CAN

299
00:10:25,200 --> 00:10:27,280
SEE PEOPLE BEING VERY JUNE

300
00:10:27,280 --> 00:10:33,440
TAKING ADVANTAGE OF SUCH AN

301
00:10:33,440 --> 00:10:34,840
OPPORTUNITY SO WHO THE RESEARCH

302
00:10:34,840 --> 00:10:36,680
AND WHAT LEVEL IS USEFUL.

303
00:10:36,680 --> 00:10:38,080
THERE ARE PRACTICAL STEPS I NEED

304
00:10:38,080 --> 00:10:39,480
TO TAKE INTO ACCOUNT.

305
00:10:39,480 --> 00:10:42,000
BECAUSE OF YOUR FOCUS ON AND HAS

306
00:10:42,000 --> 00:10:43,760
AN EQUITY FOCUS NA MEANS YOU

307
00:10:43,760 --> 00:10:46,040
HAVE TO JUST ACCORDINGLY.

308
00:10:46,040 --> 00:10:47,360
THERE'S A COUPLE THINGS, FIRST

309
00:10:47,360 --> 00:10:50,440
ACCESS IS GOING TO BE A BIT OF A

310
00:10:50,440 --> 00:10:51,680
CHALLENGE PARTICULARLY RELATIVE

311
00:10:51,680 --> 00:10:52,640
TECHNOLOGICAL ELEMENTS OF THIS

312
00:10:52,640 --> 00:10:54,160
AND NOT EVERYONE HAS A COMPUTER

313
00:10:54,160 --> 00:10:58,720
BUT EVERYONE HAS A SOPHISTICATED

314
00:10:58,720 --> 00:11:00,880
SOFTWARE AS WELL AS THE POWER TO

315
00:11:00,880 --> 00:11:02,720
USE SOME OF THIS RESEARCH AND

316
00:11:02,720 --> 00:11:04,000
PARTICULARLY IF THE WORK ITSELF

317
00:11:04,000 --> 00:11:05,280
WILL BE IMPLIED IN COMMUNITY

318
00:11:05,280 --> 00:11:06,920
SETTINGS AND THAT SORT OF THICK.

319
00:11:06,920 --> 00:11:13,760
THE SECOND PART, THERE'S THAT

320
00:11:13,760 --> 00:11:22,200
THE IN THE STRATEGIC PLAN REALLY

321
00:11:22,200 --> 00:11:24,160
DOES NEED TO JUST BE HIGHLIGHTED

322
00:11:24,160 --> 00:11:28,800
IN TERMS OF HOW YOU SEE IT BEING

323
00:11:28,800 --> 00:11:34,360
APPLIED.

324
00:11:34,360 --> 00:11:35,640
WHEN YOU THINK ABOUT THE

325
00:11:35,640 --> 00:11:37,160
POPULATION MIGHT BE SO THOSE ARE

326
00:11:37,160 --> 00:11:39,960
MY COMMENTS ON THAT AND I'LL

327
00:11:39,960 --> 00:11:40,920
KEEP THEM BRIEF.

328
00:11:40,920 --> 00:11:43,720
I THOUGHT IT WAS A GOOD IDEA, MY

329
00:11:43,720 --> 00:11:46,560
BIGGEST CHALLENGE WAS JUST

330
00:11:46,560 --> 00:11:47,680
WRAPPED AROUND IN NOT HOW IT

331
00:11:47,680 --> 00:11:50,000
MIGHT BE USED AND THAT SORT OF

332
00:11:50,000 --> 00:11:51,160
THING SO I'LL LEAVE IT THAT THE

333
00:11:51,160 --> 00:11:54,280
AND LEAVE IT TO MY COLLEAGUES.

334
00:11:54,280 --> 00:11:58,840
>>THANK YOU, VERY MUCH.

335
00:11:58,840 --> 00:12:00,240
>>THANK YOU FOR THE
OPPORTUNITY

336
00:12:00,240 --> 00:12:01,680
TO COMMENT ON THIS.

337
00:12:01,680 --> 00:12:04,240
THIS IS A GREAT PROPOSAL.

338
00:12:04,240 --> 00:12:07,800
I THINK VERY IMPORTANT DIRECTION

339
00:12:07,800 --> 00:12:09,800
AND PROBABLY NO OTHER GROUP

340
00:12:09,800 --> 00:12:12,600
OTHER THAN NIMH WOULD BE IN A

341
00:12:12,600 --> 00:12:13,800
GREAT POSITION TO PROMOTE THE

342
00:12:13,800 --> 00:12:16,200
NEXT GENERATION OF SCIENCE AND

343
00:12:16,200 --> 00:12:17,040
LEARNING HEALTH SYSTEMS GIVEN

344
00:12:17,040 --> 00:12:18,920
THE COMPLEXITIES OF WHAT WE

345
00:12:18,920 --> 00:12:19,120
FACE.

346
00:12:19,120 --> 00:12:20,920
I AGREE WITH WHAT WAS SAID

347
00:12:20,920 --> 00:12:21,280
EARLIER.

348
00:12:21,280 --> 00:12:23,360
I THINK I WOULD ADD TOO SOME

349
00:12:23,360 --> 00:12:27,800
ADDITIONAL ANGLES IN WHICH TO

350
00:12:27,800 --> 00:12:29,320
CONSIDER EXPANDING AND PROVIDING

351
00:12:29,320 --> 00:12:29,800
DETAIL.

352
00:12:29,800 --> 00:12:32,440
THE FIRST IS PERHAPS, LOOKING AT

353
00:12:32,440 --> 00:12:33,320
THE QUESTION AROUND

354
00:12:33,320 --> 00:12:35,480
INFRASTRUCTURE BECAUSE I THINK

355
00:12:35,480 --> 00:12:36,680
FOR ANY -- AND I'M GLAD YOU

356
00:12:36,680 --> 00:12:37,520
CALLED OUT IMPLEMENTATION

357
00:12:37,520 --> 00:12:39,240
SCIENCE AND THE USE OF

358
00:12:39,240 --> 00:12:40,240
IMPLEMENTATION STRATEGIES IN

359
00:12:40,240 --> 00:12:41,440
GENERAL TO MAKE THOSE SUCCESSFUL

360
00:12:41,440 --> 00:12:43,760
AND SUSTAINABLE, THERE NEEDS TO

361
00:12:43,760 --> 00:12:45,720
BE SOME REALLY GOOD FOUNDATIONAL

362
00:12:45,720 --> 00:12:49,120
RESEARCH OBJECT THE SCIO

363
00:12:49,120 --> 00:12:49,880
TECHNICAL INFRASTRUCTURE OF WHAT

364
00:12:49,880 --> 00:12:51,280
A LEARNING HEALTH SYSTEM DOES,

365
00:12:51,280 --> 00:12:52,360
PARTICULARLY ALSO WITH THE

366
00:12:52,360 --> 00:12:54,600
REALLY THE DIGITAL DIVIDE AND

367
00:12:54,600 --> 00:12:57,200
THE ISSUES AND EQUITY AROUND

368
00:12:57,200 --> 00:12:58,840
ACCESS TO ELECTRONIC HEALTHCARE

369
00:12:58,840 --> 00:13:00,600
DATA OR JUST BASICALLY EVEN JUST

370
00:13:00,600 --> 00:13:03,200
BASIC SERVICES AROUND COLLECTING

371
00:13:03,200 --> 00:13:06,160
INFORMATION IN AN AUTOMATED WAY

372
00:13:06,160 --> 00:13:08,320
ABOUT HEALTHCARE OUTCOMES TO

373
00:13:08,320 --> 00:13:10,440
MAKE THE LEARNING HEALTH SYSTEM

374
00:13:10,440 --> 00:13:11,680
FUNCTION IN GENERAL.

375
00:13:11,680 --> 00:13:18,120
THE SECOND AREA TO CONSIDER 1

376
00:13:18,120 --> 00:13:18,760
WORKFORCE.

377
00:13:18,760 --> 00:13:20,320
YOU NEED TO HAVE PROVIDERS THAT

378
00:13:20,320 --> 00:13:22,680
ARE WILLING TO IMPLEMENT THESE

379
00:13:22,680 --> 00:13:26,760
AND NOT BE BURNED OUT OR DEALING

380
00:13:26,760 --> 00:13:28,400
WITH OTHER COMPETING DEMANDS SO

381
00:13:28,400 --> 00:13:30,600
WE'RE ENHANCING THE WORK FOR,

382
00:13:30,600 --> 00:13:32,640
MENTAL HEALTH THAT CAN ALSO HAVE

383
00:13:32,640 --> 00:13:34,680
LONG-TERM OUTCOMES ON THE MENTAL

384
00:13:34,680 --> 00:13:35,720
AND PHYSICAL HEALTH OF THE

385
00:13:35,720 --> 00:13:37,560
PEOPLE THAT THEY SERVE.

386
00:13:37,560 --> 00:13:38,960
SO THAT'S ANOTHER AREA TO

387
00:13:38,960 --> 00:13:39,640
CONSIDER AND SOMETHING THAT'S

388
00:13:39,640 --> 00:13:41,720
BEEN CALLED OUT I'VE SEEN IN

389
00:13:41,720 --> 00:13:44,280
OTHER AREAS OF NIH'S WORKFORCE

390
00:13:44,280 --> 00:13:44,600
AS WELL.

391
00:13:44,600 --> 00:13:45,880
I WOULD SAY THAT I THINK THE

392
00:13:45,880 --> 00:13:47,400
FUTURE DIRECTIONS ARE ON

393
00:13:47,400 --> 00:13:49,920
IMPLEMENTATION SCIENCE IN THE

394
00:13:49,920 --> 00:13:51,120
LEARNING HEALTH SYSTEM ARE

395
00:13:51,120 --> 00:13:52,720
FORMING WHAT'S CALLED A LEARNING

396
00:13:52,720 --> 00:13:53,760
COMMUNITY AND HAVING COMMUNITY

397
00:13:53,760 --> 00:13:59,280
INPUT IN WHAT IS PRIORITIZED IN

398
00:13:59,280 --> 00:14:00,440
WHAT WE'RE LEARNING AND HOW

399
00:14:00,440 --> 00:14:02,600
WE'RE IMPLEMENTING THINGS SO

400
00:14:02,600 --> 00:14:04,000
WAYS WE CAN INVOLVE COMMUNITIES

401
00:14:04,000 --> 00:14:05,600
ACROSS THE TRANSLATE TIVE, NOT

402
00:14:05,600 --> 00:14:07,040
JUST THE LEARNING HEALTH SYSTEM

403
00:14:07,040 --> 00:14:11,040
CYCLE BUT WAYS IN WHICH THE

404
00:14:11,040 --> 00:14:12,440
COMMUNITIES COULD BE INVOLVED

405
00:14:12,440 --> 00:14:13,840
AND EMPOWERED TO SHAPE THE WAY

406
00:14:13,840 --> 00:14:15,880
THE LEARNING HEALTH SYSTEM IS

407
00:14:15,880 --> 00:14:17,120
FORMED.

408
00:14:17,120 --> 00:14:18,560
TO ACCESS THE QUESTION AND HOW

409
00:14:18,560 --> 00:14:21,280
DO WE ENGAGE WITH PEOPLE WHO MAY

410
00:14:21,280 --> 00:14:23,160
NOT HAVE REGULAR ACCESS TO

411
00:14:23,160 --> 00:14:24,280
MENTAL HEALTH HEALTH SERVICES

412
00:14:24,280 --> 00:14:25,120
WHAT WOULD THEY LOOK LIKE IN THE

413
00:14:25,120 --> 00:14:25,400
COMMUNITY.

414
00:14:25,400 --> 00:14:27,720
I WOULD SAY FINALLY ANOTHER

415
00:14:27,720 --> 00:14:36,200
ANGLE IS THINKING WITH GO AND

416
00:14:36,200 --> 00:14:37,600
PARTICULARLY WHAT CAN WE LEARN

417
00:14:37,600 --> 00:14:40,360
FROM MOW AND MIDDLE INCOMMUTE

418
00:14:40,360 --> 00:14:41,520
COUNTRIES IN TERMS OF WHAT

419
00:14:41,520 --> 00:14:44,600
THEY'VE DONE ON A SHOW STRING

420
00:14:44,600 --> 00:14:46,200
BUDGET THAT IN LEARNING THE

421
00:14:46,200 --> 00:14:48,280
HEALTH SYSTEM SO THOSE WERE

422
00:14:48,280 --> 00:14:49,600
THOUGHTS TO ENHANCE AND

423
00:14:49,600 --> 00:14:51,280
HOPEFULLY THEY CAN BE HELPFUL

424
00:14:51,280 --> 00:14:52,560
AND PLUSH IT OUT AND ENHANCING

425
00:14:52,560 --> 00:14:54,000
WHAT YOU'VE CREATED IN THIS

426
00:14:54,000 --> 00:14:57,280
GREAT AREA.

427
00:14:57,280 --> 00:14:57,640
THANK YOU.

428
00:14:57,640 --> 00:14:59,000
>>THANK YOU, AMY.

429
00:14:59,000 --> 00:15:02,840
OPEN IT UP FOR OTHERS.

430
00:15:02,840 --> 00:15:04,560
>>I KNEW IT WAS SOMETHING
I

431
00:15:04,560 --> 00:15:04,840
LEFT OFF.

432
00:15:04,840 --> 00:15:08,440
I HAVE TWO OTHER COMMENTS ON

433
00:15:08,440 --> 00:15:09,000
THIS.

434
00:15:09,000 --> 00:15:12,400
BECAUSE THE NATURE OF THE, WHAT

435
00:15:12,400 --> 00:15:17,720
YOU -- THE CONCEPT ITSELF, THE

436
00:15:17,720 --> 00:15:19,320
MECHANISM OF SUPPORT IS OPENED

437
00:15:19,320 --> 00:15:20,040
UP SO YOU HAVE DIFFERENT LEVELS

438
00:15:20,040 --> 00:15:24,320
OF THAT AND EVERYTHING FROM A

439
00:15:24,320 --> 00:15:26,280
SMALL THREE TO A VERY LARGE ONE

440
00:15:26,280 --> 00:15:30,400
AND SECOND OF ALL, THE SCOPE OF

441
00:15:30,400 --> 00:15:31,160
SCHOLARSHIPS NEEDS TO BE OPEN

442
00:15:31,160 --> 00:15:34,360
BECAUSE TO AS MANY OF THE DHS

443
00:15:34,360 --> 00:15:35,760
AGENCIES THAT YOU COULD PARTNER

444
00:15:35,760 --> 00:15:40,080
WITH REGARDING THIS BECAUSE YOU

445
00:15:40,080 --> 00:15:41,960
ARE LOOKING AT IMPLEMENTATION

446
00:15:41,960 --> 00:15:52,040
AND APPTATION IN DIVERSE SETS.

447
00:15:52,040 --> 00:15:57,400
OTHER COMMENTS OR QUESTIONS?

448
00:15:57,400 --> 00:16:00,280
>>RELATED ACTUALLY

449
00:16:00,280 --> 00:16:02,720
INCORPORATING BOTH DISCUSSANTS

450
00:16:02,720 --> 00:16:04,560
IS AROUND THE ALL OUTS FOR THE

451
00:16:04,560 --> 00:16:06,920
EARLY PSYCHOSIS NETWORK AND

452
00:16:06,920 --> 00:16:08,240
THROUGH SAMHSA HAS A DIFFERENT

453
00:16:08,240 --> 00:16:12,840
KIND OF FUNDING INFRASTRUCTURE

454
00:16:12,840 --> 00:16:13,800
FOR COMMUNITIES ORGANIZATIONS TO

455
00:16:13,800 --> 00:16:15,760
PARTICIPATE WITH ACADEMIC

456
00:16:15,760 --> 00:16:19,400
INSTITUTIONS, ET CETERA SO I

457
00:16:19,400 --> 00:16:29,920
THINK THAT BECAUSE THIS IS GOING

458
00:16:30,680 --> 00:16:32,840
TO BE A REALLY BIG LIST FOR THE

459
00:16:32,840 --> 00:16:35,720
COMMUNITY ORGANIZATIONS WHO ARE

460
00:16:35,720 --> 00:16:37,440
ALREADY DEALING WITH A

461
00:16:37,440 --> 00:16:38,040
SIGNIFICANT WORKFORCE ISSUE.

462
00:16:38,040 --> 00:16:42,560
THIS IS SUCH A NEED AROUND JUST

463
00:16:42,560 --> 00:16:43,960
REFLECTIVE PRACTICE AND BECOMING

464
00:16:43,960 --> 00:16:44,920
ORIENTED AROUND DATA AND

465
00:16:44,920 --> 00:16:46,440
OUTCOMES SO IT'S WONDERFUL FROM

466
00:16:46,440 --> 00:16:48,160
THAT REGARD BUT IT'S THE SAME

467
00:16:48,160 --> 00:16:49,200
PEOPLE WHO WILL BE CALLED THEN

468
00:16:49,200 --> 00:16:52,160
TO DO ALL THE OTHER THINGS.

469
00:16:52,160 --> 00:16:53,360
SO LEVERAGING SOME OF THE WAYS

470
00:16:53,360 --> 00:16:57,320
THAT THE SUPPORT IS FOR EARLY

471
00:16:57,320 --> 00:17:00,520
PSYCHOSIS AS WELL AS WOULD BE

472
00:17:00,520 --> 00:17:05,280
NICE.

473
00:17:05,280 --> 00:17:15,480
>>GO AHEAD.

474
00:17:38,040 --> 00:17:39,240
IT'S WHERE YOU COULD USE

475
00:17:39,240 --> 00:17:41,840
TECHNOLOGY TO AUTOMATE A LOT OF

476
00:17:41,840 --> 00:17:42,560
DATA COLLECTION THAT THEY HAVE

477
00:17:42,560 --> 00:17:44,040
TO DO AND A LOT OF THE CHARTED

478
00:17:44,040 --> 00:17:46,520
AND EVEN A LOT OF THE SCORING

479
00:17:46,520 --> 00:17:51,640
AND SO ON AND SO, IDEALLY, THIS

480
00:17:51,640 --> 00:17:52,600
WOULD FREE UP COMMISSIONS AND

481
00:17:52,600 --> 00:17:54,920
MORE DEMANDS ON THEM AND MAYBE

482
00:17:54,920 --> 00:18:04,280
MANY FOR SUCCESS.

483
00:18:04,280 --> 00:18:07,960
>>

484
00:18:07,960 --> 00:18:09,680
>>AS YOU THINK ABOUT IT
AND IT

485
00:18:09,680 --> 00:18:11,240
SEEMS LIKE A STRENGTH HERE BUT

486
00:18:11,240 --> 00:18:12,480
MY UNDERSTANDING FROM THE

487
00:18:12,480 --> 00:18:16,360
PSYCHOSIS WORK IS THE IMPORTANCE

488
00:18:16,360 --> 00:18:19,040
OF CONNECTING TO INTERNISTS AND

489
00:18:19,040 --> 00:18:19,880
OTHER MEDICAL INDIVIDUALS THAT

490
00:18:19,880 --> 00:18:21,360
MIGHT FIRST SEE PATIENTS,

491
00:18:21,360 --> 00:18:24,600
PARTICULARLY IN RURAL

492
00:18:24,600 --> 00:18:25,280
COMMUNITIES AND HOW MUCH AS SOON

493
00:18:25,280 --> 00:18:26,840
AS YOU FOCUS ON HEALTH CLINICS

494
00:18:26,840 --> 00:18:28,440
AND I JUST WONDERED HOW MUCH THE

495
00:18:28,440 --> 00:18:30,320
ROLE OF BEING ABLE TO CONNECT TO

496
00:18:30,320 --> 00:18:31,760
OTHER MORE GENERAL CLINICS AND

497
00:18:31,760 --> 00:18:33,280
IT MIGHT BE WHERE PEOPLE ARE

498
00:18:33,280 --> 00:18:34,600
FIRST SEEING THAT SEEMS ONE OF

499
00:18:34,600 --> 00:18:35,640
THE ACCESS CHALLENGES BECAUSE

500
00:18:35,640 --> 00:18:39,040
THEY MAY NOT HAVE THE

501
00:18:39,040 --> 00:18:40,400
CONNECTIONS TO THE MEDICAL

502
00:18:40,400 --> 00:18:41,360
RECORDS BUT IT'S A CASE WHERE

503
00:18:41,360 --> 00:18:43,320
YOU CAN HAVE THE BIGGEST IMPACT

504
00:18:43,320 --> 00:18:45,520
JUST IN THE FIRST EPISODE OF

505
00:18:45,520 --> 00:18:49,880
PSYCHOSIS AND THAT MIGHT BE NOT

506
00:18:49,880 --> 00:18:51,040
JUST GENERAL PRACTITIONERS BUT

507
00:18:51,040 --> 00:18:54,960
SCHOOL SYSTEMS AND BE THE HIGH

508
00:18:54,960 --> 00:18:56,480
SCHOOL OR COLLEGE SYSTEMS SO I

509
00:18:56,480 --> 00:18:57,960
JUST WONDER HOW MUCH IT'S

510
00:18:57,960 --> 00:18:58,960
THOUGHT OF.

511
00:18:58,960 --> 00:19:00,160
IT DIDN'T SEEM IN WHAT YOU

512
00:19:00,160 --> 00:19:03,280
PRESENTED TO BE AS BROAD AS IT

513
00:19:03,280 --> 00:19:06,280
MIGHT BE THINKING ABOUT GENERAL

514
00:19:06,280 --> 00:19:06,880
PRACTITIONERS IN THE MENTAL

515
00:19:06,880 --> 00:19:08,280
SENSE AND CLINICAL PSYCHOLOGISTS

516
00:19:08,280 --> 00:19:12,240
IN THE HIGH SCHOOL.

517
00:19:12,240 --> 00:19:13,480
>>THANK YOU FOR THAT
QUESTION.

518
00:19:13,480 --> 00:19:16,560
I THINK IN BOTH OF THE EXAMPLES

519
00:19:16,560 --> 00:19:18,440
OF THE CLINICS FOR FIRST EPISODE

520
00:19:18,440 --> 00:19:22,480
SIGH SEW SIS AND THE CERTIFIED

521
00:19:22,480 --> 00:19:23,640
COMMUNITY BEHAVIORAL HEALTH

522
00:19:23,640 --> 00:19:25,120
CLINICS THERE'S A GOAL THERE TO

523
00:19:25,120 --> 00:19:28,760
SINK INTEGRATED CARE PHYSICAL

524
00:19:28,760 --> 00:19:31,680
HEALTHCARE AS WELL AS CARE FOR

525
00:19:31,680 --> 00:19:37,280
THEIR PSYCHIATRIC CONDITIONS

526
00:19:37,280 --> 00:19:38,800
WITH PROVIDERS AND PRIMARY CARE

527
00:19:38,800 --> 00:19:41,880
AND SO FOURTH AND IT'S BEEN SEEN

528
00:19:41,880 --> 00:19:43,400
AS A ESTABLISHING THOSE

529
00:19:43,400 --> 00:19:45,320
RELATIONSHIPS WOULD BE A WAY OF

530
00:19:45,320 --> 00:19:46,240
BENEFITING GROUPS AND PEOPLE

531
00:19:46,240 --> 00:19:48,200
COULD BE IDENTIFIED EARLIER IN

532
00:19:48,200 --> 00:19:50,080
THEIR STAGE OF ILLNESS AND REFER

533
00:19:50,080 --> 00:19:52,440
THEM TO APPROPRIATE CARE AND

534
00:19:52,440 --> 00:19:55,720
THEN ALSO WHEN PEOPLE COMPLETE

535
00:19:55,720 --> 00:19:58,640
THEIR ACUTE CARE THAT THERE'S

536
00:19:58,640 --> 00:20:01,000
THAT CONNECTION AND WE'VE DONE

537
00:20:01,000 --> 00:20:02,760
BETTER WITH THAT THEN WE HAVE IN

538
00:20:02,760 --> 00:20:04,720
INTEGRATING MAKING THOSE SCHOOL

539
00:20:04,720 --> 00:20:07,680
SYSTEMS AND SO THAT IS CERTAINLY

540
00:20:07,680 --> 00:20:08,920
IN THE PRESIDENT'S REPORTS THAT

541
00:20:08,920 --> 00:20:11,760
WAS IDENTIFIED AS AN AREA THAT

542
00:20:11,760 --> 00:20:12,800
NEEDS GREET ERA TENSION AND THAT

543
00:20:12,800 --> 00:20:15,200
WOULD BE SOMETHING THAT WOULD

544
00:20:15,200 --> 00:20:16,440
DEFINITELY BE ENCOURAGED THROUGH

545
00:20:16,440 --> 00:20:20,960
AN INITIATIVE LIKE THIS.

546
00:20:20,960 --> 00:20:22,680
THANK YOU VERY MUCH, BOB.

547
00:20:22,680 --> 00:20:25,480
WE'LL MOVE ON.

548
00:20:25,480 --> 00:20:35,960
WE'RE MOVING ON TO MICHAEL.

549
00:20:36,840 --> 00:20:37,760
>>Michael: THANK YOU SO
MUCH.

550
00:20:37,760 --> 00:20:39,600
YES ON BEHALF OF THE DIVISION OF

551
00:20:39,600 --> 00:20:41,320
AIDS RESEARCH IT'S MY PLEASURE

552
00:20:41,320 --> 00:20:45,200
TO PRESENT OUR CONCEPT ON

553
00:20:45,200 --> 00:20:46,800
ADVANCING HIV TESTING THROUGH

554
00:20:46,800 --> 00:20:49,840
PHARMACY AND PHARMACISTS.

555
00:20:49,840 --> 00:20:55,880
AND THE NEXT SLIDE, PLEASE.

556
00:20:55,880 --> 00:20:56,960
SO OUR INTEREST IN PHARMACIES

557
00:20:56,960 --> 00:20:59,080
HAS BEEN REINFORCED, THE

558
00:20:59,080 --> 00:21:00,800
DRAMATIC IMPACT THAT PHARMACIES

559
00:21:00,800 --> 00:21:03,080
HAVE HAD ON REACHING CONSUMERS

560
00:21:03,080 --> 00:21:10,360
FOR COVID-19 VACCINES DELIVERY.

561
00:21:10,360 --> 00:21:12,920
THEY HAVE DELIVERED MORE THAN

562
00:21:12,920 --> 00:21:16,880
300 MILLION VACCINE DOSES

563
00:21:16,880 --> 00:21:17,800
THROUGH 40,000 PHARMACY

564
00:21:17,800 --> 00:21:19,680
LOCATIONS NATIONWIDE IN THIS

565
00:21:19,680 --> 00:21:20,920
DEMONSTRATION SERVES AS A PROVE

566
00:21:20,920 --> 00:21:22,640
OF CONCEPT OF THE INCREDIBLE

567
00:21:22,640 --> 00:21:24,400
REACH AND IMPACT THAT PHARMACY

568
00:21:24,400 --> 00:21:32,080
PROGRAMS CAN HAVE.

569
00:21:32,080 --> 00:21:33,560
PHARMACIES CAN OFFER MANY

570
00:21:33,560 --> 00:21:35,720
ADVANTAGES TO HIV SERVICE

571
00:21:35,720 --> 00:21:37,680
DELIVERY AS WELL.

572
00:21:37,680 --> 00:21:39,520
THIS INCLUDES CONVENIENT WEEKEND

573
00:21:39,520 --> 00:21:41,200
AND EVENING HOURS AS WELL AS

574
00:21:41,200 --> 00:21:42,720
NEIGHBORHOOD LOCATIONS.

575
00:21:42,720 --> 00:21:47,680
FOR EXAMPLE, IT IS ESTIMATED

576
00:21:47,680 --> 00:21:49,000
THAT AMERICANS LIVE WITHIN FIVE

577
00:21:49,000 --> 00:21:53,720
MILES OF A PHARMACY AND

578
00:21:53,720 --> 00:21:55,920
PHARMACISTS RESERVE HIGH RATINGS

579
00:21:55,920 --> 00:21:58,600
IN CONSUMER TRUST AND THEY'RE AS

580
00:21:58,600 --> 00:21:59,640
STIGMATIZING ENVIRONMENTS IN

581
00:21:59,640 --> 00:22:03,640
WHICH TO ACCESS HEALTHCARE.

582
00:22:03,640 --> 00:22:05,160
THE RETAIL PHARMACIES IN RECENT

583
00:22:05,160 --> 00:22:06,800
YEARS HAVE EXPANDED THE DELIVERY

584
00:22:06,800 --> 00:22:09,760
OF CLINICAL SERVICES WITHIN THE

585
00:22:09,760 --> 00:22:12,040
LOCATIONS TO BASIC HEALTHCARE

586
00:22:12,040 --> 00:22:15,200
NEEDS BEYOND THE RECEIPT OF

587
00:22:15,200 --> 00:22:16,360
PRESCRIPTIONS.

588
00:22:16,360 --> 00:22:18,240
FOR THOSE REASONS THE CURRENT

589
00:22:18,240 --> 00:22:21,000
U.N. NATIONAL HIV/AIDS STRATEGY

590
00:22:21,000 --> 00:22:22,160
HIGHLIGHTS THE KEY ROLE THAT

591
00:22:22,160 --> 00:22:23,360
PHARMACIES AND PHARMACISTS CAN

592
00:22:23,360 --> 00:22:26,040
PLAY IN A COMPREHENSIVE APPROACH

593
00:22:26,040 --> 00:22:28,240
TO HIV PREVENTION AND CARE AS

594
00:22:28,240 --> 00:22:31,440
STATED ON THIS SLIDE.

595
00:22:31,440 --> 00:22:35,360
THE NEXT SLIDE, PLEASE.

596
00:22:35,360 --> 00:22:37,200
SO THIS INITIATIVE WOULD HAVE

597
00:22:37,200 --> 00:22:39,440
TWO PRIMARY GOALS MANY OF THE

598
00:22:39,440 --> 00:22:43,720
FIRST TO SUPPORT RESEARCH TO

599
00:22:43,720 --> 00:22:45,120
FURTHER KA PASS TATE AND STALE

600
00:22:45,120 --> 00:22:46,640
TESTED AND PREVENTION AND CARE

601
00:22:46,640 --> 00:22:49,640
THROUGH PHARMACISTS AND PHARMACY

602
00:22:49,640 --> 00:22:50,360
SETTINGS.

603
00:22:50,360 --> 00:22:52,600
AND THE SECOND IS TO ADVANCE

604
00:22:52,600 --> 00:22:54,360
TRAINING AND PROGRAMS TO ENABLE

605
00:22:54,360 --> 00:22:55,760
PHARMACY STUDENTS, PHARMACISTS

606
00:22:55,760 --> 00:23:06,240
AND PHARMACIES THESE ARE TWIN

607
00:23:06,680 --> 00:23:11,120
GOALS COMPLIMENTARY TO ONE

608
00:23:11,120 --> 00:23:11,840
ANOTHER.

609
00:23:11,840 --> 00:23:13,360
ZOO, SOME RESEARCH QUESTIONS TO

610
00:23:13,360 --> 00:23:15,320
PURSUE ON THIS TOPIC WILL

611
00:23:15,320 --> 00:23:18,400
INCLUDE THEY'RE NOT LIMITED TO,

612
00:23:18,400 --> 00:23:20,720
IS PHARMACY BASED SCREENINGS FOR

613
00:23:20,720 --> 00:23:22,560
MULTIPLE CHRONIC ILLNESSES

614
00:23:22,560 --> 00:23:23,960
INCLUDING HIV INCREASE THE USE

615
00:23:23,960 --> 00:23:27,160
OF HIV TESTING.

616
00:23:27,160 --> 00:23:28,600
HOW CAN PHARMACY SUPPORT THE

617
00:23:28,600 --> 00:23:31,400
TAKE AND DELIVERY OF HIV

618
00:23:31,400 --> 00:23:33,000
PREVENTATIVE MEDICINE INCLUDING

619
00:23:33,000 --> 00:23:36,280
NOVEL INJECTABLE PREP REGIMENTS.

620
00:23:36,280 --> 00:23:38,680
CAN PHARMACY PRESCRIPTION

621
00:23:38,680 --> 00:23:39,840
MONITORING IDENTIFY PEOPLE WITH

622
00:23:39,840 --> 00:23:40,920
REFILLS WHO ARE AT RISK OF

623
00:23:40,920 --> 00:23:46,640
DROPPING OUT OF HIV CARE AND

624
00:23:46,640 --> 00:23:47,840
HELP WITH MAINTAINING CARE.

625
00:23:47,840 --> 00:23:50,280
AND FINALLY, WHAT TRAINING

626
00:23:50,280 --> 00:23:51,840
CURRICULUM CAN IMPROVE THE

627
00:23:51,840 --> 00:23:55,080
CAPACITY FOR PHARMACIES AND

628
00:23:55,080 --> 00:23:56,560
PHARMACY STUDENTS TO SUPPORT HIV

629
00:23:56,560 --> 00:24:00,080
TESTING PREVENTION AND CARE?

630
00:24:00,080 --> 00:24:01,360
OUR KA VISION WOULD BE EXCITE

631
00:24:01,360 --> 00:24:03,120
TODAY PURSUE ANSWERS TO THESE

632
00:24:03,120 --> 00:24:04,520
AND OTHER QUESTIONS THROUGH THIS

633
00:24:04,520 --> 00:24:09,720
INITIATIVE AND WE PRESSURE

634
00:24:09,720 --> 00:24:10,320
ATTENTION AND WE WELCOME YOUR

635
00:24:10,320 --> 00:24:12,240
INPUT AND WE'RE GLAD TO ADDRESS

636
00:24:12,240 --> 00:24:12,640
ANY QUESTIONS.

637
00:24:12,640 --> 00:24:14,280
>>THANK YOU, MICHAEL.

638
00:24:14,280 --> 00:24:23,120
SO WE HAVE DRUNK DRI DOCTOR TELD

639
00:24:23,120 --> 00:24:24,120
MURRAY.

640
00:24:24,120 --> 00:24:24,240
>>

641
00:24:24,240 --> 00:24:25,720
>>THANK YOU, VERY MUCH.

642
00:24:25,720 --> 00:24:27,000
SO THANK YOU AGAIN FOR THE

643
00:24:27,000 --> 00:24:30,520
OPPORTUNITY TO REVIEW THIS.

644
00:24:30,520 --> 00:24:31,680
APPROXIMATE I ENJOYED READING

645
00:24:31,680 --> 00:24:32,240
IT.

646
00:24:32,240 --> 00:24:34,320
SO I HAVE A LOT OF -- I WOULDN'T

647
00:24:34,320 --> 00:24:39,240
SAY A LOT, RELATIVELY POINTED

648
00:24:39,240 --> 00:24:43,200
QUESTIONS ON IT SO THE WHOLE

649
00:24:43,200 --> 00:24:45,760
IDEA OF THE PHARMACISTS ON THE

650
00:24:45,760 --> 00:24:47,240
INCREASING ROLE THE FIRST THING

651
00:24:47,240 --> 00:24:49,120
THAT COMES UP IS THE WORKFORCE

652
00:24:49,120 --> 00:24:50,840
QUESTION RELATED TO TRAINING AND

653
00:24:50,840 --> 00:24:52,560
I KNOW THAT THIS MIGHT -- IF

654
00:24:52,560 --> 00:25:02,960
IT'S OUTSIDE THE SCOPE OF THIS,

655
00:25:02,960 --> 00:25:04,480
TRAINING TO ADVANCE THE SKILLS

656
00:25:04,480 --> 00:25:06,240
OF KNOWLEDGE OF PHARMACISTS

657
00:25:06,240 --> 00:25:07,960
MAINLY BECAUSE OF THE WAY

658
00:25:07,960 --> 00:25:09,400
THEY'RE TRAINED AT DIFFERENT

659
00:25:09,400 --> 00:25:12,880
LEVELS AND DIFFERENT TYPES SO SO

660
00:25:12,880 --> 00:25:14,200
IT'S A VERY IMPORTANT PART.

661
00:25:14,200 --> 00:25:19,120
THE OTHER PART IS THE FIT WHAT

662
00:25:19,120 --> 00:25:26,000
IS IN PART WHAT WHERE IS THIS

663
00:25:26,000 --> 00:25:27,960
ROLE AND THE FIT THERE IN TERMS

664
00:25:27,960 --> 00:25:29,920
OF YEAR WORK AND IN YOUR AREA

665
00:25:29,920 --> 00:25:31,120
AND I HOPE IT'S CLEAR.

666
00:25:31,120 --> 00:25:32,920
WHAT I'M TRYING TO GET AT WHERE

667
00:25:32,920 --> 00:25:37,120
WOULD THE FIT WE SO THAT WHEN IT

668
00:25:37,120 --> 00:25:39,560
IS PRESENTED TO THE PHARMACISTS,

669
00:25:39,560 --> 00:25:40,960
LIKE THE PHARMACIST ASSOCIATION

670
00:25:40,960 --> 00:25:45,440
THAT THING THEY CAN SAY OKAY WE

671
00:25:45,440 --> 00:25:46,760
HAVE A CLEAR IDEA OF HOW THIS IS

672
00:25:46,760 --> 00:25:48,040
DONE AND HERE IS HOW WE CAN DO

673
00:25:48,040 --> 00:25:48,400
THIS.

674
00:25:48,400 --> 00:25:54,480
BECAUSE THE WAY I KNOW WOMEN IN

675
00:25:54,480 --> 00:25:55,960
RURAL AREAS THERE'S A CRITICAL

676
00:25:55,960 --> 00:26:02,120
ROLE THAT ASSOCIATIONS PLAY IN

677
00:26:02,120 --> 00:26:04,520
BEING ABLE TO ROLLOUT THIS WORK

678
00:26:04,520 --> 00:26:08,560
SO THAT'S CRITICALLY IMPORTANT

679
00:26:08,560 --> 00:26:11,840
AND SO THE DESIGN IS GOING TO BE

680
00:26:11,840 --> 00:26:12,800
CRITICAL HERE AND BECAUSE OF THE

681
00:26:12,800 --> 00:26:20,000
TYPE OF WORK THAT'S BEING DONE

682
00:26:20,000 --> 00:26:22,440
BECAUSE YOU ARE LOOKING AT BOTH

683
00:26:22,440 --> 00:26:24,760
DOMESTIC AND GLOBAL AND PHARMACY

684
00:26:24,760 --> 00:26:25,680
SERVICES IN GLOBAL SIGHTINGS

685
00:26:25,680 --> 00:26:30,200
HAVE A RURAL CHALLENGE BECAUSE

686
00:26:30,200 --> 00:26:33,720
THEY'RE DEALING WITH EVERYDAY

687
00:26:33,720 --> 00:26:34,920
WITH THE FAKE INFORMATION

688
00:26:34,920 --> 00:26:36,520
CHALLENGE THAT GOES OUT SO

689
00:26:36,520 --> 00:26:40,240
DEPENDING ON WHERE IT IS THAT

690
00:26:40,240 --> 00:26:47,320
THIS MIGHT BE BECAUSE QUALITY

691
00:26:47,320 --> 00:26:48,080
SCROLL ASSURANCE IS GOING TO BE

692
00:26:48,080 --> 00:26:54,480
YOUR BIGGEST THING AND WHEN IT'S

693
00:26:54,480 --> 00:26:56,440
NOT DONE THIS ROLLOUT FAILS AND

694
00:26:56,440 --> 00:26:57,720
FALLS FLAT AND IT'S HARD TO

695
00:26:57,720 --> 00:26:58,840
RECOVER FROM THAT SO THAT WOULD

696
00:26:58,840 --> 00:27:03,160
BE SOMETHING THAT IT WENT

697
00:27:03,160 --> 00:27:05,680
THROUGH OFTEN IT'S VERY TRUE THE

698
00:27:05,680 --> 00:27:06,920
MODELS ARE CRITICAL HOWEVER THE

699
00:27:06,920 --> 00:27:09,240
BIG CHALLENGE THAT ARE ALSO

700
00:27:09,240 --> 00:27:14,280
SEEING THAT I'M NOT SURE THIS IS

701
00:27:14,280 --> 00:27:15,680
WHERE MAYBE ANOTHER CAN HELP YOU

702
00:27:15,680 --> 00:27:18,960
WITH SAMHSA AND IT'S THE SOCIAL

703
00:27:18,960 --> 00:27:29,440
POLITICAL AND CULTURAL TYPE OF

704
00:27:37,040 --> 00:27:40,960
IS ELIGIBLE AND THE IF IT'S

705
00:27:40,960 --> 00:27:44,840
DIRECTED TO THEM AND YOU ARE

706
00:27:44,840 --> 00:27:47,320
FAMILIAR WITH THE CONCEPT OF THE

707
00:27:47,320 --> 00:27:49,360
POLITICAL AND THAT PLAYS A BIG

708
00:27:49,360 --> 00:27:51,000
ROLE HERE AND THAT BECAUSE OF

709
00:27:51,000 --> 00:27:53,600
STIGMA AND OTHER THINGS SO IT

710
00:27:53,600 --> 00:27:55,040
MAY BE IMPORTANT MANY OF I WOULD

711
00:27:55,040 --> 00:27:56,920
ALSO LOOK AT THE REFERRAL

712
00:27:56,920 --> 00:27:57,720
PROCESS BECAUSE ONE OF THE

713
00:27:57,720 --> 00:27:59,720
THINGS THAT PHARMACISTS NOW ARE

714
00:27:59,720 --> 00:28:00,960
DOING IN I'M SURE YOU KNOW THIS

715
00:28:00,960 --> 00:28:03,120
IS THAT THEY'RE ALSO RECOGNIZING

716
00:28:03,120 --> 00:28:08,000
THAT THERE ARE CO-MORBIDITY AND

717
00:28:08,000 --> 00:28:10,480
MENTAL HEALTH AND A LOT OF

718
00:28:10,480 --> 00:28:12,240
PERSONS HAVE AND SO A MECHANISM

719
00:28:12,240 --> 00:28:13,680
THEY CAN INCREASE AND BE MORE

720
00:28:13,680 --> 00:28:17,720
PRECISE WITH THE REFERRAL IN THE

721
00:28:17,720 --> 00:28:19,320
OTHER MENTAL HEALTH HEALTH

722
00:28:19,320 --> 00:28:20,120
PROFESSIONALS O OF ONE TIME OR

723
00:28:20,120 --> 00:28:21,480
ANOTHER WILL BE VERY IMPORTANT

724
00:28:21,480 --> 00:28:30,720
TO DO AND BECAUSE THIS IS A

725
00:28:30,720 --> 00:28:31,800
INTERVENTION BASED TYPE OF

726
00:28:31,800 --> 00:28:33,400
RESEARCH IT CAN BE REPLICATED

727
00:28:33,400 --> 00:28:37,360
AND EXPANDED IN DIVERSE PHYSICAL

728
00:28:37,360 --> 00:28:41,960
AND SOCIAL TYPE OF ENVIRONMENT

729
00:28:41,960 --> 00:28:43,400
AND AGAIN, BECAUSE YOU ARE

730
00:28:43,400 --> 00:28:48,080
RIGHTLY SO, TALKING ABOUT

731
00:28:48,080 --> 00:28:50,360
SUCCESSFUL BOTTLES LIKE PREP AND

732
00:28:50,360 --> 00:28:51,520
OTHER APPROACHES THE PHYSICAL

733
00:28:51,520 --> 00:28:54,560
AND SOCIAL BEHAVIORAL ISSUES

734
00:28:54,560 --> 00:28:56,640
THAT EXIST WITH THE EXPANSION

735
00:28:56,640 --> 00:29:03,120
WILL BE VERY IMPORTANT.

736
00:29:03,120 --> 00:29:05,520
FOR THE MOMENT THAT'S ALL I

737
00:29:05,520 --> 00:29:05,720
HAVE.

738
00:29:05,720 --> 00:29:06,440
>>THANK YOU.

739
00:29:06,440 --> 00:29:10,440
>>GREAT SUMMARY FROM Dr.

740
00:29:10,440 --> 00:29:12,280
TELFAIR AND I WAS EXCITED HAVING

741
00:29:12,280 --> 00:29:13,440
THE OPPORTUNITY TO READ THIS

742
00:29:13,440 --> 00:29:15,720
CONCEPT AND SO I REVIEW WITH

743
00:29:15,720 --> 00:29:21,080
GREAT ENTHUSIASM WITH ALSO

744
00:29:21,080 --> 00:29:27,200
CONCERNS ABOUT FACE PHARMACY

745
00:29:27,200 --> 00:29:28,560
DESERTS IN RURAL COMMUNITIES AND

746
00:29:28,560 --> 00:29:32,360
IN URBAN COMMUNITIES AND SO IT

747
00:29:32,360 --> 00:29:41,960
WAS ABOUT THE RAISING IS TARGET

748
00:29:41,960 --> 00:29:43,600
FORWARD THIS AND A REASON FOR

749
00:29:43,600 --> 00:29:46,800
THIS AS AN OUTLET IS BECAUSE OF

750
00:29:46,800 --> 00:29:48,480
THE NEEDING TO REACH PARTICULAR

751
00:29:48,480 --> 00:29:51,000
POPULATIONS WHERE ACCESS IS AN

752
00:29:51,000 --> 00:29:56,080
ISSUE AND SO IT'S ASKING

753
00:29:56,080 --> 00:29:57,120
QUESTIONS ABOUT HOW DO WE

754
00:29:57,120 --> 00:29:59,320
IDENTIFY WAYS TO OVERCOME THOSE

755
00:29:59,320 --> 00:30:01,000
CHALLENGES THAT YOU MENTIONED IN

756
00:30:01,000 --> 00:30:06,320
YOUR CONCEPT PAPER AS FOR THE

757
00:30:06,320 --> 00:30:12,920
POPULATIONS THAT AGAIN ARE IS

758
00:30:12,920 --> 00:30:14,000
HOW WOULD YOU UTILIZE AND LIKE

759
00:30:14,000 --> 00:30:15,680
THE IDEA OF THE LEARNING

760
00:30:15,680 --> 00:30:19,720
COMMUNITIES MENTIONED EARLIER IS

761
00:30:19,720 --> 00:30:21,200
IN THE PROCESS OF THINKING ABOUT

762
00:30:21,200 --> 00:30:28,920
THIS PLATFORM AND THE OTHER

763
00:30:28,920 --> 00:30:33,120
SEARCH IS BEING ABLE TO LOOK

764
00:30:33,120 --> 00:30:38,960
MORE AT THE SOCIAL POLITICAL

765
00:30:38,960 --> 00:30:43,120
STRUCTURE AND REALLY AS A

766
00:30:43,120 --> 00:30:46,920
POTENTIAL TESTING SITE FOR PREP

767
00:30:46,920 --> 00:30:48,560
AND THE OTHER IDEA I THOUGHT

768
00:30:48,560 --> 00:30:55,840
ABOUT WAS BEING ABLE TO

769
00:30:55,840 --> 00:30:58,680
PHARMACIES IN STATES WHERE

770
00:30:58,680 --> 00:31:00,840
FUNDING FOR HIV WAS NOT BEING

771
00:31:00,840 --> 00:31:02,760
RECEIVED WELL AND IN FACT I'M IN

772
00:31:02,760 --> 00:31:07,840
A STATE WHERE CDC FUNDING FOR

773
00:31:07,840 --> 00:31:09,960
HIV HAS BEEN DENIED AND THEY'RE

774
00:31:09,960 --> 00:31:14,320
NOT ACCEPTING THE FUNDING.

775
00:31:14,320 --> 00:31:24,520
HOW MUCH THAT EVEN IF ENOUGH

776
00:31:24,520 --> 00:31:27,120
THOSE PHARMACIST AND THEY WILL

777
00:31:27,120 --> 00:31:30,480
HAVE TO DEAL WITH THIS POLL ITS

778
00:31:30,480 --> 00:31:32,360
FALLOUT AS THEY UPTAKE THIS AS A

779
00:31:32,360 --> 00:31:39,720
MODEL FOR DISTRIBUTING PREP AND

780
00:31:39,720 --> 00:31:43,560
HOW MIGHT THERE BE WAYS TO

781
00:31:43,560 --> 00:31:45,280
LEVERAGE THE PIONEERING EFFORTS

782
00:31:45,280 --> 00:31:47,320
UNDERTAKEN AS A WAY OF LEARNING

783
00:31:47,320 --> 00:31:54,360
HOW TO DO THIS AND THEN FINALLY,

784
00:31:54,360 --> 00:31:55,280
IT'S TO THINK ABOUT WAYS IN

785
00:31:55,280 --> 00:31:57,440
WHICH THE SERVICES THAT MAY BE

786
00:31:57,440 --> 00:32:04,040
IMPLEMENTED IN PHARMACIES FOR

787
00:32:04,040 --> 00:32:05,080
PREP THEY ARE DOING THIS WORK

788
00:32:05,080 --> 00:32:07,360
TRYING TO IDENTIFY WAYS TO

789
00:32:07,360 --> 00:32:17,880
INCREASE PREP UPTAKE TARGETING

790
00:32:18,720 --> 00:32:21,800
THE POPULATIONS AND HOW MIGHT

791
00:32:21,800 --> 00:32:26,080
RESEARCH TO BE DESIGNED WHERE

792
00:32:26,080 --> 00:32:35,200
THERE'S CO OF THE CHALLENGES

793
00:32:35,200 --> 00:32:36,080
THAT IS GOING TO OCCUR AND WE

794
00:32:36,080 --> 00:32:37,760
HAVE TO ADMIT THAT ACCESS IS

795
00:32:37,760 --> 00:32:44,840
GOING TO BE A CRITICAL ISSUE AND

796
00:32:44,840 --> 00:32:46,920
SO SIMILAR TO WHAT WE SAW WITH

797
00:32:46,920 --> 00:32:51,200
COVID-19 IN TERMS OF WHO GREATER

798
00:32:51,200 --> 00:32:52,760
ACCESS TO THE SERVICES NEED AND

799
00:32:52,760 --> 00:32:55,040
WILL WE FIND A REP LATATION WITH

800
00:32:55,040 --> 00:33:01,160
THE CONCEPT YOU ARE PROMOTING

801
00:33:01,160 --> 00:33:02,720
WITH THIS APPROACH TO REACH

802
00:33:02,720 --> 00:33:04,040
LARGER POPULATIONS THAT DON'T

803
00:33:04,040 --> 00:33:08,880
HAVE ACCESS TO AND READILY

804
00:33:08,880 --> 00:33:11,040
UPTAKE PREP AS A CONFERENCE OF

805
00:33:11,040 --> 00:33:15,120
LOTS OF BARRIERS INCLUDING

806
00:33:15,120 --> 00:33:16,320
SOCIAL STIGMA BUT A GREAT IDEA

807
00:33:16,320 --> 00:33:17,760
AND LOOKING FORWARD TO ABOUT

808
00:33:17,760 --> 00:33:25,080
WHAT MIGHT COME NEXT.

809
00:33:25,080 --> 00:33:29,720
>>OPENING UP IT FOR
COMMENTS OR

810
00:33:29,720 --> 00:33:30,000
QUESTIONS.

811
00:33:30,000 --> 00:33:33,840
>>

812
00:33:33,840 --> 00:33:37,160
>>THIS IS A CON SPENT IT
HAD TO

813
00:33:37,160 --> 00:33:38,440
DO WITH CO-MORBIDITIES AND YOU

814
00:33:38,440 --> 00:33:40,080
MIGHT INCLUDE AMONGST THE TOPICS

815
00:33:40,080 --> 00:33:43,880
HOW CAN YOU EQUIP THESE

816
00:33:43,880 --> 00:33:48,120
PHARMACISTS TO BE RESOURCES SO

817
00:33:48,120 --> 00:33:52,400
MIGHT YOU INCLUDE HOW COULD

818
00:33:52,400 --> 00:33:54,160
KNOWLEDGE AROUND OST AS WELL AS

819
00:33:54,160 --> 00:33:56,640
PREP BE OF VALUE TO PHARMACISTS

820
00:33:56,640 --> 00:33:58,520
AND HOW COULD PHARMACISTS

821
00:33:58,520 --> 00:33:59,440
RESOURCES FOR PEOPLE SEEKING

822
00:33:59,440 --> 00:34:01,080
HARM REDUCTION ALONG WITH HIV

823
00:34:01,080 --> 00:34:11,480
AND OTHER HIV SERVICES.

824
00:34:18,040 --> 00:34:18,560
>>THANK YOU.

825
00:34:18,560 --> 00:34:22,480
I WAS INTERESTED IN HEARING HOW

826
00:34:22,480 --> 00:34:26,960
THE HIV COMMUNITY IS GOING TO BE

827
00:34:26,960 --> 00:34:29,040
INVOLVED IN IS STRUCTUREING AND

828
00:34:29,040 --> 00:34:33,760
DEVISING SERVICES THAT MIGHT BE

829
00:34:33,760 --> 00:34:40,720
HELPFUL.

830
00:34:40,720 --> 00:34:49,960
>>THERE ARE WAYS WE HAVE
INPUT

831
00:34:49,960 --> 00:34:52,240
AND HOLD A MEETING LATER THIS

832
00:34:52,240 --> 00:34:56,880
YEAR AND AT WHICH WE GET

833
00:34:56,880 --> 00:34:59,520
ADVISEMENT FROM MANY SECTORS NOT

834
00:34:59,520 --> 00:35:01,120
JUST PHARMACY AND PHARMACY

835
00:35:01,120 --> 00:35:02,320
ASSOCIATIONS AND THEY ALSO FROM

836
00:35:02,320 --> 00:35:03,560
THE COMMUNITY FROM COMMUNITY

837
00:35:03,560 --> 00:35:11,720
MEMBERS IS THEMSELVES AND I

838
00:35:11,720 --> 00:35:14,200
APPRECIATE THE RESEARCH TEAMS

839
00:35:14,200 --> 00:35:15,400
AND HOW WE APPROXIMATE ENSURE

840
00:35:15,400 --> 00:35:16,680
EVERYONE IS AT THE TABLE TO HELP

841
00:35:16,680 --> 00:35:21,000
DRIVE THE RESEARCH AND THEN TO

842
00:35:21,000 --> 00:35:22,160
INVOLVE COMMUNITY INPUT AS WE

843
00:35:22,160 --> 00:35:23,760
TRIED TO BUILD THE PROGRAMS THAT

844
00:35:23,760 --> 00:35:24,920
WILL DELIVER THESE SERVICES

845
00:35:24,920 --> 00:35:28,200
WHETHER IT'S TESTING AND WE HAVE

846
00:35:28,200 --> 00:35:29,840
PROGRAM AND SO WE WANTED MAKE

847
00:35:29,840 --> 00:35:31,800
SURE AS WE PIONEER THIS PROGRAM

848
00:35:31,800 --> 00:35:36,080
AND WE SCALE BACK, THE IT'S IN A

849
00:35:36,080 --> 00:35:38,480
WAY THAT IS ACCEPTABLE AND

850
00:35:38,480 --> 00:35:39,280
DESIRABLE FOR THE COMMUNITIES

851
00:35:39,280 --> 00:35:43,480
AND FOR THOSE WHO CAN MOST

852
00:35:43,480 --> 00:35:47,200
BENEFIT.

853
00:35:47,200 --> 00:35:48,800
IT'S A VALUE WE SHARE AND

854
00:35:48,800 --> 00:35:54,520
SOMETHING THAT WE WILL

855
00:35:54,520 --> 00:35:54,840
PRIORITIZE.

856
00:35:54,840 --> 00:35:56,280
>>WE'LL GO AHEAD AND MOVE
ALONG

857
00:35:56,280 --> 00:35:58,360
TO OUR LAST CONCEPT CLEARANCE

858
00:35:58,360 --> 00:35:59,400
FOR I DAY.

859
00:35:59,400 --> 00:36:01,840
PRESENTED BY Dr. THERESA SENN

860
00:36:01,840 --> 00:36:03,680
FOCUSED ON STREAMLINING MENTAL

861
00:36:03,680 --> 00:36:06,480
HEALTH INTERVENTIONS FOR YOUTH

862
00:36:06,480 --> 00:36:09,640
LIVING WITH HIV.

863
00:36:09,640 --> 00:36:10,760
>>THANK YOU FOR THE
OPPORTUNITY

864
00:36:10,760 --> 00:36:13,200
TO PRESENT THIS INITIATIVE ON

865
00:36:13,200 --> 00:36:14,440
STREAMLINING MENTAL HEALTH

866
00:36:14,440 --> 00:36:15,280
INTERVENTIONS FOR YOUTH LIVING

867
00:36:15,280 --> 00:36:17,480
WITH LIVE AND LOW AND MIDDLE

868
00:36:17,480 --> 00:36:18,040
INCOME COUNTRIES.

869
00:36:18,040 --> 00:36:20,680
I WANT TO ACKNOWLEDGE MY

870
00:36:20,680 --> 00:36:21,720
COLLEAGUE EQUAL CONTRIBUTIONS TO

871
00:36:21,720 --> 00:36:29,080
THE INITIATIVE.

872
00:36:29,080 --> 00:36:31,080
AT LESS ENTERS AND YOUNG PEOPLE

873
00:36:31,080 --> 00:36:33,840
REPRESENT A GROWING SHARE OF

874
00:36:33,840 --> 00:36:37,080
PEOPLE LIVING WITH HIV WITH 1.75

875
00:36:37,080 --> 00:36:38,600
MID YUN LIVING WITH HIV

876
00:36:38,600 --> 00:36:39,280
GLOBALLY.

877
00:36:39,280 --> 00:36:41,320
YOUTH LIVING WITH HIV HAVE POOR

878
00:36:41,320 --> 00:36:44,840
OUTCOMES ALONG THE HIV CARE

879
00:36:44,840 --> 00:36:45,320
CONTINUUM.

880
00:36:45,320 --> 00:36:46,920
THIS IS LOW RATES OF VIRAL

881
00:36:46,920 --> 00:36:48,280
SUPPRESSION EVEN WHEN THERE'S

882
00:36:48,280 --> 00:36:51,680
ACCESS TO RETRO FIE RAL THERAPY

883
00:36:51,680 --> 00:36:54,680
IN ADDITION, THERE'S MENTAL

884
00:36:54,680 --> 00:36:55,800
HEALTH ORDERS OF YOUTH LIVING

885
00:36:55,800 --> 00:36:57,720
WITH HIV AND THEY ARE ASSOCIATED

886
00:36:57,720 --> 00:37:00,120
WITH POOR HIV CARE CONTINUUM

887
00:37:00,120 --> 00:37:03,360
OUTCOMES.

888
00:37:03,360 --> 00:37:07,680
NEXT SLIDE.

889
00:37:07,680 --> 00:37:08,560
THEY ARE UNIQUE PERIODS OF

890
00:37:08,560 --> 00:37:09,640
DEVELOPMENT THERE'S INCREASED

891
00:37:09,640 --> 00:37:12,880
ONSET OF COMMON MENTAL DISORDERS

892
00:37:12,880 --> 00:37:15,280
AND RAPID BRAIN DEVELOPMENT,

893
00:37:15,280 --> 00:37:16,920
SHIFTING SOCIAL AND HEIGHTENED

894
00:37:16,920 --> 00:37:22,720
CONCERNS AROUND STIGMA.

895
00:37:22,720 --> 00:37:24,800
THREE FACE CHALLENGE AS THEY

896
00:37:24,800 --> 00:37:27,840
TRANSITION TO SERVICES AND

897
00:37:27,840 --> 00:37:29,360
NAVIGATE NEW ROMANTIC

898
00:37:29,360 --> 00:37:30,480
RELATIONSHIPS AND MOVE OUT OF

899
00:37:30,480 --> 00:37:31,320
THE FAMILY HOME AND BECOME

900
00:37:31,320 --> 00:37:35,360
PARENTS THEMSELVES.

901
00:37:35,360 --> 00:37:37,440
THEY MAY NEED TO BE ADAPTED TO

902
00:37:37,440 --> 00:37:39,280
THESE UNIQUE CONTEMPTS

903
00:37:39,280 --> 00:37:40,680
ADDITIONALLY IN MANY LOW AND

904
00:37:40,680 --> 00:37:42,520
MIDDLE INCOME COUNTRIES THERE

905
00:37:42,520 --> 00:37:43,920
ARE NOT ENOUGH MENTAL HEALTH

906
00:37:43,920 --> 00:37:45,120
PROVIDERS FOR THE POPULATION IN

907
00:37:45,120 --> 00:37:47,280
NEED OF SERVICES AND THIS MENTAL

908
00:37:47,280 --> 00:37:49,360
HEALTH GAP IS PARTICULARLY ACUTE

909
00:37:49,360 --> 00:37:51,400
FOR YOUTH MENTAL HEALTH WORKERS

910
00:37:51,400 --> 00:38:01,960
AND WITH AN ESTIMATED .01 YOUTH

911
00:38:05,000 --> 00:38:05,520
NEXT SLIDE.

912
00:38:05,520 --> 00:38:06,840
THEREFORE, THE GOAL FOR THIS

913
00:38:06,840 --> 00:38:11,880
INITIATIVE, IS TO ADAPT FOR

914
00:38:11,880 --> 00:38:13,480
YOUTH LIVING WITH HIV IN LOW AND

915
00:38:13,480 --> 00:38:18,720
MIDDLE INCOME COUNTRIES TO

916
00:38:18,720 --> 00:38:21,120
IMPROVE PROVIDERS AND

917
00:38:21,120 --> 00:38:23,440
IMPLEMENTERS TO THEY WANT TO

918
00:38:23,440 --> 00:38:24,000
EVIDENCE MENTAL HEALTH IN A

919
00:38:24,000 --> 00:38:24,720
EVIDENCE BASED WAY BUT DON'T

920
00:38:24,720 --> 00:38:27,680
HAVE THE RESOURCES TO DELIVER

921
00:38:27,680 --> 00:38:31,280
COMPLEX SESSIONS.

922
00:38:31,280 --> 00:38:33,280
THE FIRST IS TAILORING

923
00:38:33,280 --> 00:38:34,640
INTERVENTIONS AND SO THESE

924
00:38:34,640 --> 00:38:35,720
INTERVENTIONS WOULD NEED TO BE

925
00:38:35,720 --> 00:38:37,240
TAILORED TO THE FACTORS UNIQUE

926
00:38:37,240 --> 00:38:39,200
TO ADOLESCENTS LIVING WITH HIV

927
00:38:39,200 --> 00:38:41,360
AND AS DISCUSSED ON THE PREVIOUS

928
00:38:41,360 --> 00:38:42,040
SLIDE.

929
00:38:42,040 --> 00:38:44,320
AND THE SECOND COMPONENT IS SLAM

930
00:38:44,320 --> 00:38:45,760
TRAINING FOR INTERVENTIONS BY

931
00:38:45,760 --> 00:38:48,360
THIS WE BROADLY HAVE BEEN USING

932
00:38:48,360 --> 00:38:50,520
FEWER RESOURCES LIKE TIME OR

933
00:38:50,520 --> 00:39:00,120
MONEY OR NUMBER OF PROVIDERS.

934
00:39:00,120 --> 00:39:06,320
SO SOME ARE THINGS LIKE WHAT

935
00:39:06,320 --> 00:39:07,760
ADAPTATIONS NOR THE UNIQUE

936
00:39:07,760 --> 00:39:08,920
CONTEMPT OF ADOLESCENTS LIVING

937
00:39:08,920 --> 00:39:09,720
WITH HIV.

938
00:39:09,720 --> 00:39:11,240
WHAT ARE THE CRITICAL COMPONENTS

939
00:39:11,240 --> 00:39:13,240
OR THE MINIMAL DOSE OF AN

940
00:39:13,240 --> 00:39:14,360
INTERVENTION THAT MUST BE

941
00:39:14,360 --> 00:39:16,680
DELIVERED TO ACHIEVE MEANINGFUL

942
00:39:16,680 --> 00:39:17,720
IMPROVEMENTS AND AT WHAT POINT

943
00:39:17,720 --> 00:39:24,040
SHOULD WE INTENSIFY SORRY LISTEN

944
00:39:24,040 --> 00:39:28,080
WHAT STRATEGIES IS COULD BE USED

945
00:39:28,080 --> 00:39:29,480
WHILE MAINTAINING AND HOW CAN WE

946
00:39:29,480 --> 00:39:31,080
MATCH THE APPROPRIATE

947
00:39:31,080 --> 00:39:33,760
INTERVENTION ARE THE APPROPRIATE

948
00:39:33,760 --> 00:39:38,440
INTENSITY INTER CONVENIENCE.

949
00:39:38,440 --> 00:39:42,160
THANK YOU AND I LOOK FORWARD TO

950
00:39:42,160 --> 00:39:42,680
THE COUNCIL DISCUSSION.

951
00:39:42,680 --> 00:39:43,600
>>THANK YOU VERY MUCH.

952
00:39:43,600 --> 00:39:45,760
IT'S Dr. COLLINS AND Dr.

953
00:39:45,760 --> 00:39:47,080
LIGHT FOOT YOU ARE BOTH IN THE

954
00:39:47,080 --> 00:39:51,880
ROOM YOU CAN CAN CHOSE WHO GOES

955
00:39:51,880 --> 00:39:53,880
FIRST.

956
00:39:53,880 --> 00:39:55,120
>>THANK YOU THIS IS A
MUCH

957
00:39:55,120 --> 00:39:56,760
NEEDED CONCEPT AND I'M SO HAPPY

958
00:39:56,760 --> 00:39:59,760
TO SEE THIS AND WE KNOW THAT

959
00:39:59,760 --> 00:40:03,600
THERE'S A DIRT  DERTH ON INTERVS

960
00:40:03,600 --> 00:40:05,480
FOR PEEL LIVING WITH IF HIV AND

961
00:40:05,480 --> 00:40:11,600
THIS LACK OF HIGH-QUALITY

962
00:40:11,600 --> 00:40:12,480
RESEARCH IT'S DIFFICULT FOR LOW

963
00:40:12,480 --> 00:40:15,680
AND MIDDLE INCOME COUNTRIES AND

964
00:40:15,680 --> 00:40:19,000
ALSO IF YOU CAN ACHIEVE THE

965
00:40:19,000 --> 00:40:22,920
FIRST GOAL THAT GIVES US OPTIONS

966
00:40:22,920 --> 00:40:25,760
AND WHERE HIV IS MOST PREVALENT

967
00:40:25,760 --> 00:40:27,280
AND YOU HIGHLIGHTED THE

968
00:40:27,280 --> 00:40:28,200
DEVELOPMENTAL CONTEXT AND I

969
00:40:28,200 --> 00:40:32,480
THINK THIS IS AN OPPORTUNITY TO

970
00:40:32,480 --> 00:40:34,320
IS LEARN MORE ABOUT CULTURAL

971
00:40:34,320 --> 00:40:36,240
ENVIRONMENTS FOR WHICH THEY'RE

972
00:40:36,240 --> 00:40:37,320
NOT MUCH DATA SO PAYING

973
00:40:37,320 --> 00:40:38,760
ATTENTION TO OH, WHAT ARE THEY

974
00:40:38,760 --> 00:40:40,120
IF YOU THINK ABOUT ADOLESCENTS

975
00:40:40,120 --> 00:40:50,640
IF YOU THINK ABOUT THE EARLY TO

976
00:40:55,120 --> 00:40:58,480
AND HOW THEY'RE IMPORTANT AND SO

977
00:40:58,480 --> 00:41:02,440
I'M THINKING ABOUT WHAT MIGHT BE

978
00:41:02,440 --> 00:41:06,920
SOME OF THE IS RESEARCH AREAS

979
00:41:06,920 --> 00:41:08,520
AND HOW MIGHT THEY BE DESIGNED

980
00:41:08,520 --> 00:41:10,840
TO ADDRESS ADOLESCENTS JOURNEY

981
00:41:10,840 --> 00:41:11,560
THROUGH DISCLOSURE HIV STATUS

982
00:41:11,560 --> 00:41:14,600
AND MANAGEMENT OF TREATMENT

983
00:41:14,600 --> 00:41:18,680
FATIGUE AND SOME OF THE GENDER

984
00:41:18,680 --> 00:41:19,880
SPECIFIC ELEMENTS AND THE OTHER

985
00:41:19,880 --> 00:41:21,040
STRESSORS YOU HIGHLIGHTED AND

986
00:41:21,040 --> 00:41:23,320
WHAT DO WE UNDERSTAND ABOUT

987
00:41:23,320 --> 00:41:25,200
PARENTAL AND CAREGIVER

988
00:41:25,200 --> 00:41:25,760
INVOLVEMENT IN MENTAL HEALTH

989
00:41:25,760 --> 00:41:28,680
INTERVENTIONS AND SOME LIKE

990
00:41:28,680 --> 00:41:31,640
INVOLVE PARENTS OR CAREGIVERS

991
00:41:31,640 --> 00:41:33,040
AND WHAT CAN WE LEARN ABOUT WHEN

992
00:41:33,040 --> 00:41:35,000
AND WHERE TO NOT CORPORATE THOSE

993
00:41:35,000 --> 00:41:39,200
KINDS OF CAREGIVER ROLES AND THE

994
00:41:39,200 --> 00:41:42,800
QUESTION OF DOSING I THINK IS

995
00:41:42,800 --> 00:41:44,920
IMPORTANT SINCE WE SEE ATTRITION

996
00:41:44,920 --> 00:41:46,160
FROM MENTAL HEALTH HEALTHCARE

997
00:41:46,160 --> 00:41:49,000
PARTICULARLY IN SOME OF THE

998
00:41:49,000 --> 00:41:53,080
INTEGRATED SETTINGS AND HIV CARE

999
00:41:53,080 --> 00:41:55,240
AND SO IS THERE A BENEFIT FROM

1000
00:41:55,240 --> 00:41:56,840
SINGLE SESSION INTERVENTIONS

1001
00:41:56,840 --> 00:41:59,000
ENABLING PEOPLE TO EXPLORE THE

1002
00:41:59,000 --> 00:41:59,680
WHOLE GAMUT WOULD BE IMPORTANT

1003
00:41:59,680 --> 00:42:03,080
AND FIGURING OUT FOR WHOM.

1004
00:42:03,080 --> 00:42:06,920
I THINK THE OTHER ASPECT OF WHAT

1005
00:42:06,920 --> 00:42:08,080
I SEEN IN SOME OF THE WORK THAT

1006
00:42:08,080 --> 00:42:13,120
WE DO WHEN THE CARIBBEAN IS

1007
00:42:13,120 --> 00:42:16,400
OFTEN FIGURING OUT WHAT KINDS OF

1008
00:42:16,400 --> 00:42:17,560
INTERVENTION CAN HAVE SYMPTOMS

1009
00:42:17,560 --> 00:42:22,000
BECAUSE YOUNG PEOPLE MAY BE MORE

1010
00:42:22,000 --> 00:42:23,720
DISTRESSED AND AND WILL NOT BE

1011
00:42:23,720 --> 00:42:25,720
ABLE TO BE LINKED TO MENTAL

1012
00:42:25,720 --> 00:42:26,920
HEALTH SERVICES.

1013
00:42:26,920 --> 00:42:30,280
EXAMING WHO SHOULD DELIVER THESE

1014
00:42:30,280 --> 00:42:31,040
FOR YOUNG PEOPLE.

1015
00:42:31,040 --> 00:42:33,000
PEER CENTERED OR OTHER PROVIDERS

1016
00:42:33,000 --> 00:42:37,160
AND WHAT IS THE CONTEXT.

1017
00:42:37,160 --> 00:42:38,680
SHOULD THEY BE OUTSIDE OF THE

1018
00:42:38,680 --> 00:42:49,200
CLINIC AND HEALTH AND WHEN YOU

1019
00:42:53,120 --> 00:42:54,120
THINK ABOUT JUST INTERVENTION

1020
00:42:54,120 --> 00:42:55,960
IT'S GOING TO BE IN THIS CONTEXT

1021
00:42:55,960 --> 00:42:59,720
THAT MAY EITHER DISCOURAGE

1022
00:42:59,720 --> 00:43:01,800
ENGAGEMENT OR SO I WOULD INCLUDE

1023
00:43:01,800 --> 00:43:05,040
SOMETHING ABOUT THAT AND THEN

1024
00:43:05,040 --> 00:43:09,560
THE LAST TWO THINGS MAY BE I

1025
00:43:09,560 --> 00:43:10,720
THINK AS WE KNOW THERE'S

1026
00:43:10,720 --> 00:43:12,120
ATTENTION TO ENGAGING YOUNG

1027
00:43:12,120 --> 00:43:13,560
PEOPLE ON THE INTERVENTIONS THAT

1028
00:43:13,560 --> 00:43:16,840
ARE DEVELOPED FOR THEM SO MAKING

1029
00:43:16,840 --> 00:43:21,920
THAT A REQUIREMENT AND FINALLY I

1030
00:43:21,920 --> 00:43:32,480
WOULD SAY, AND I'LL OWING CARING

1031
00:43:36,760 --> 00:43:38,320
PEOPLE WITH RESEARCH HIV

1032
00:43:38,320 --> 00:43:40,040
PROGRAMS AND ACTUALLY LINKING

1033
00:43:40,040 --> 00:43:41,440
THEM TO THE EXISTING MENTAL

1034
00:43:41,440 --> 00:43:42,280
HEALTH HEALTH SERVICES AND

1035
00:43:42,280 --> 00:43:50,440
DIFFERENT SETTINGS, THANK YOU.

1036
00:43:50,440 --> 00:43:53,280
>>I WAS VERY EXCITED TO
SEE

1037
00:43:53,280 --> 00:43:53,840
THIS.

1038
00:43:53,840 --> 00:43:55,720
THERE IS AN INCREDIBLE NEED FOR

1039
00:43:55,720 --> 00:43:57,760
MENTAL HEALTH SERVICES FOR YOUNG

1040
00:43:57,760 --> 00:44:00,280
PEOPLE AND LMICs.

1041
00:44:00,280 --> 00:44:03,160
IT'S HARD TO SEE THIS

1042
00:44:03,160 --> 00:44:04,760
ACKNOWLEDGMENT OF THE WORKFORCE

1043
00:44:04,760 --> 00:44:06,160
REALITY AND SOME OF THE TASK

1044
00:44:06,160 --> 00:44:08,800
SHIFTING THAT MAY NEED TO HAPPEN

1045
00:44:08,800 --> 00:44:09,760
FROM MENTAL HEALTH HEALTH

1046
00:44:09,760 --> 00:44:11,680
INTERVENTIONS TO USE A NON

1047
00:44:11,680 --> 00:44:12,760
PROFESSIONAL WORKFORCE AND IN

1048
00:44:12,760 --> 00:44:14,440
ORDER TO DELIVER THIS PLAN OF

1049
00:44:14,440 --> 00:44:21,400
WORK AND SO JUST I ALSO WANTED

1050
00:44:21,400 --> 00:44:25,440
TO UNDERSCORE WITH Dr. COLLINS

1051
00:44:25,440 --> 00:44:26,720
SAID ABOUT THE THE RELATIONSHIP

1052
00:44:26,720 --> 00:44:31,560
WITH PARENTS AND HOW THOSE AND

1053
00:44:31,560 --> 00:44:33,760
HOW CAREGIVERS ARE INVOLVED AND

1054
00:44:33,760 --> 00:44:37,000
THEY HAVE UNITE CHALLENGES AND

1055
00:44:37,000 --> 00:44:40,600
THINKING ABOUT HOW THOSE

1056
00:44:40,600 --> 00:44:41,760
INTERSECT WITH MENTAL HEALTH AND

1057
00:44:41,760 --> 00:44:45,040
CHARGES YOUNG PEOPLE HAVE FACED.

1058
00:44:45,040 --> 00:44:47,000
A FEW OTHER THINGS TO CONSIDER.

1059
00:44:47,000 --> 00:44:48,880
ONE THING THAT IS RELATED TO

1060
00:44:48,880 --> 00:44:52,880
Dr. COLLINS TALKED ABOUT IS

1061
00:44:52,880 --> 00:44:56,640
THAT THERE'S NRMIC AND AND

1062
00:44:56,640 --> 00:44:58,960
CHARGES TO PROVIDING YOUTH

1063
00:44:58,960 --> 00:45:01,240
FRIENDLY SPACES AND IN ORDER TO

1064
00:45:01,240 --> 00:45:05,120
PROVIDE CARE SO IT SEEMS PART OF

1065
00:45:05,120 --> 00:45:06,720
THAT IS PIECE AROUND WHERE IS

1066
00:45:06,720 --> 00:45:07,960
THIS HAPPENED AND THIS YOUTH

1067
00:45:07,960 --> 00:45:09,920
FRIENDLY SPACE AND CREATING

1068
00:45:09,920 --> 00:45:12,720
PLACES WHERE YOUNG PEOPLE FEEL

1069
00:45:12,720 --> 00:45:17,320
COMFORTABLE GOING IS IMPORTANT.

1070
00:45:17,320 --> 00:45:24,040
OF THERE'S LIKELY TO BE IS A

1071
00:45:24,040 --> 00:45:29,680
LACK OF DOCUMENTING AND AMONG

1072
00:45:29,680 --> 00:45:30,920
YOUNG PEOPLE AND THERE ROOM IN

1073
00:45:30,920 --> 00:45:35,120
ORDER TO PROVIDE THE OPPORTUNITY

1074
00:45:35,120 --> 00:45:37,000
TO DOCUMENT THE NEED AND SCOPE

1075
00:45:37,000 --> 00:45:40,280
AND OTHERWISE IT WOULD BE

1076
00:45:40,280 --> 00:45:41,360
CHALLENGES AND FOR INVESTIGATORS

1077
00:45:41,360 --> 00:45:43,080
TO JUSTIFY AND WRITE THAT

1078
00:45:43,080 --> 00:45:43,800
PROBLEM STATEMENT IN THE

1079
00:45:43,800 --> 00:45:47,920
RESEARCH TO REVIEW GROUPS.

1080
00:45:47,920 --> 00:45:49,800
AND WHILE THEY'RE A FEW

1081
00:45:49,800 --> 00:45:52,160
INTERVENTIONS OUT THERE TO

1082
00:45:52,160 --> 00:45:54,840
ADJUST MENTAL AND MANY, MANY

1083
00:45:54,840 --> 00:45:57,160
MORE WERE NEEDED AND IT'S

1084
00:45:57,160 --> 00:45:58,480
EXCITING THIS IS INTENDED TO

1085
00:45:58,480 --> 00:46:01,960
JUMP START THAT AREA.

1086
00:46:01,960 --> 00:46:06,040
ALTHOUGH THIS STARTS WITH

1087
00:46:06,040 --> 00:46:16,560
ADAPTATION AND IT WOULD BE AN

1088
00:46:21,920 --> 00:46:22,880
INCREDIBLE CONTRIBUTION.

1089
00:46:22,880 --> 00:46:24,960
I'VE TRIED ADAPTING MENTAL

1090
00:46:24,960 --> 00:46:27,240
HEALTH CONCEPT S WITH MY NIH NOT

1091
00:46:27,240 --> 00:46:29,200
INTERVENTION WORK SO EMOTIONAL

1092
00:46:29,200 --> 00:46:30,600
REGULATION SKILLS YOU TALK ABOUT

1093
00:46:30,600 --> 00:46:35,320
HEALINGS AND THOSE KINDS OF

1094
00:46:35,320 --> 00:46:36,280
THINGS AND THERE'S DEFINITELY

1095
00:46:36,280 --> 00:46:39,440
DIFFERENCES IN HOW PEOPLE THINK

1096
00:46:39,440 --> 00:46:42,040
ABOUT MENTAL HEALTH, EMOTIONS,

1097
00:46:42,040 --> 00:46:43,680
FEELINGS AND SO SOME OF THAT IS

1098
00:46:43,680 --> 00:46:49,600
REALLY GOING TO HAVE TO THOUGHT

1099
00:46:49,600 --> 00:46:53,360
ABOUT SO THERE'S DISCUSSION AND

1100
00:46:53,360 --> 00:46:54,560
FLUENCY AROUND MENTAL HEALTH

1101
00:46:54,560 --> 00:46:58,080
SOCIAL MEDIA CULTURAL REL VAN

1102
00:46:58,080 --> 00:47:00,040
SEE STARTS WITH THE NEED TO

1103
00:47:00,040 --> 00:47:02,480
START WITH CULTURALLY RELEVANT

1104
00:47:02,480 --> 00:47:03,640
INTERVENTIONS NOT JUST

1105
00:47:03,640 --> 00:47:06,800
CULTURALLY TAILORED BECAUSE

1106
00:47:06,800 --> 00:47:07,760
GIVEN THE SCOPE OF THE CHANGES

1107
00:47:07,760 --> 00:47:09,480
YOU WERE TALKING ABOUT ARE

1108
00:47:09,480 --> 00:47:11,680
NECESSARY IN INTERVENTIONS TO

1109
00:47:11,680 --> 00:47:14,680
MAKE THEM RELEVANT FOR LMICs

1110
00:47:14,680 --> 00:47:16,080
AND YOU MAY FIND YOU HAVE A

1111
00:47:16,080 --> 00:47:17,160
DIFFERENT INTERVENTION THAT

1112
00:47:17,160 --> 00:47:21,360
WHERE YOU STARTED AND SO, AN

1113
00:47:21,360 --> 00:47:23,000
EXAMPLE OF SOME OF THIS

1114
00:47:23,000 --> 00:47:27,560
CULTURALLY RELEVANT OR WE WERE

1115
00:47:27,560 --> 00:47:31,800
DOING THIS EMOTIONAL REGULATION

1116
00:47:31,800 --> 00:47:32,920
AND OF WE WERE TALKING ABOUT

1117
00:47:32,920 --> 00:47:35,000
THEIR FEELINGS AND THEY WERE

1118
00:47:35,000 --> 00:47:36,640
LIKE WELL WHAT DO YOU MEAN BY

1119
00:47:36,640 --> 00:47:40,400
FEELINGS?

1120
00:47:40,400 --> 00:47:43,440
HOW DO YOU NOT TACTILE AS

1121
00:47:43,440 --> 00:47:45,040
OPPOSED TO EMOTIONS WHEN WE WE

1122
00:47:45,040 --> 00:47:48,960
TALKED ABOUT EMOTIONS IT WAS

1123
00:47:48,960 --> 00:47:51,160
CHALLENGING BECAUSE IT'S NOT

1124
00:47:51,160 --> 00:47:52,880
SOMETHING THEY TALKED WITH THEM

1125
00:47:52,880 --> 00:47:55,440
ABOUT SO, AGAIN, THIS NEED FOR

1126
00:47:55,440 --> 00:47:56,680
CUL ACTUALLY RELEVANT

1127
00:47:56,680 --> 00:47:57,400
INTERVENTIONS IS GOING TO BE

1128
00:47:57,400 --> 00:48:01,040
IMPORTANT AND I WOULD ALSO

1129
00:48:01,040 --> 00:48:02,440
ADVOCATE FOR INTERVENTIONS THAT

1130
00:48:02,440 --> 00:48:06,120
ARE LOCALLY DEVELOPED AS OPPOSED

1131
00:48:06,120 --> 00:48:06,920
TO ONLY FAVORING WESTERN

1132
00:48:06,920 --> 00:48:08,800
INTERVENTIONS SO ALLOWING THE

1133
00:48:08,800 --> 00:48:10,440
ASSETS TO BE DEPLOYED AND IN

1134
00:48:10,440 --> 00:48:13,360
COMMUNITIES AS WE TRY TO ADDRESS

1135
00:48:13,360 --> 00:48:16,040
NOT MENTAL HEALTH ISSUES AND

1136
00:48:16,040 --> 00:48:16,520
LMICs.

1137
00:48:16,520 --> 00:48:17,920
THE PIECE MIGHT BE GOOD TO

1138
00:48:17,920 --> 00:48:21,320
REALLY INCLUDE IS THE CAPACITY

1139
00:48:21,320 --> 00:48:22,680
OF THE INFRASTRUCTURE SUPPORT

1140
00:48:22,680 --> 00:48:27,680
AND SCAFFOLDING NEEDED IN THESE

1141
00:48:27,680 --> 00:48:29,480
VARIOUS SETTINGS AND THE LAST

1142
00:48:29,480 --> 00:48:31,480
THING I'LL SAY IS REALLY

1143
00:48:31,480 --> 00:48:33,320
APPRECIATED HOW THE STRATEGIC

1144
00:48:33,320 --> 00:48:35,360
FRAMEWORK FOR ADDRESSING YOUTH

1145
00:48:35,360 --> 00:48:37,840
MENTAL HEALTH DISPARITIES TOOK A

1146
00:48:37,840 --> 00:48:40,960
PROCEED BROOCH TO UNDERSTANDING

1147
00:48:40,960 --> 00:48:42,560
AND I WONDER IF THAT PROCEED

1148
00:48:42,560 --> 00:48:43,960
APPROACH MIGHT BE USEFUL HERE

1149
00:48:43,960 --> 00:48:45,600
BUT I'M REALLY EXCITED ABOUT

1150
00:48:45,600 --> 00:48:47,240
THIS AND REALLY DO HOPE THAT IT

1151
00:48:47,240 --> 00:48:51,360
MOVES FORWARD SO THANK YOU FOR

1152
00:48:51,360 --> 00:48:56,120
DEVELOPING THIS.

1153
00:48:56,120 --> 00:49:00,280
>>THANK YOU SO MUCH.

1154
00:49:00,280 --> 00:49:02,520
PATRICIA.

1155
00:49:02,520 --> 00:49:05,320
>>THANK YOU FOR THIS
PROPOSAL.

1156
00:49:05,320 --> 00:49:09,640
I HAD -- I HAVE NO EXPERTISE IN

1157
00:49:09,640 --> 00:49:10,320
THIS AREA.

1158
00:49:10,320 --> 00:49:12,840
IN ANYWAY YOU COULD CONSTRUE IT

1159
00:49:12,840 --> 00:49:18,600
BUT I LOOKED FOR THE IMPACT OF

1160
00:49:18,600 --> 00:49:21,760
CONGENITAL HIV AND I WAS

1161
00:49:21,760 --> 00:49:22,800
WONDERING -- THEY'RE ONLY LIKE

1162
00:49:22,800 --> 00:49:27,560
HALF A DOZEN PAPERS ON THE

1163
00:49:27,560 --> 00:49:29,840
BEHAVIORAL ASPECTS OF CONGENITAL

1164
00:49:29,840 --> 00:49:31,600
HIV DONE IN ANY SYSTEMATIC WAY

1165
00:49:31,600 --> 00:49:35,560
WHATSOEVER AND I WAS WONDERING

1166
00:49:35,560 --> 00:49:37,880
IF THIS WAS PART OF YOUR PLAN OR

1167
00:49:37,880 --> 00:49:39,240
AN OBSTACLE TO YOUR PLAN OR HOW

1168
00:49:39,240 --> 00:49:47,880
YOU WERE GOING TO DEAL WITH IT.

1169
00:49:47,880 --> 00:49:50,640
I THINK AS THE HIV EPIDEMIC

1170
00:49:50,640 --> 00:49:54,000
CHANGES AND THERE'S BEEN A LOT

1171
00:49:54,000 --> 00:49:56,960
OF RAMP UP SERVICES WE'RE SEEING

1172
00:49:56,960 --> 00:49:58,880
SOME CHANGES AND THE AT LESS

1173
00:49:58,880 --> 00:50:05,280
ENTER HIV EPIDEMIC AND THERE'S

1174
00:50:05,280 --> 00:50:07,680
FEWER WITH ADOLESCENTS WHO

1175
00:50:07,680 --> 00:50:09,760
ACQUIRE HIV LATER IN LIFE

1176
00:50:09,760 --> 00:50:14,000
ALTHOUGH THERE'S DEFINITELY

1177
00:50:14,000 --> 00:50:17,320
STILL A GROUP AND IT'S SOMETHING

1178
00:50:17,320 --> 00:50:21,360
THAT WILL BE IMPORTANT FOR FOLKS

1179
00:50:21,360 --> 00:50:27,560
TO CONSIDER AND THINK ABOUT AS

1180
00:50:27,560 --> 00:50:27,760
WELL.

1181
00:50:27,760 --> 00:50:32,280
>>SO THANK YOU FOR THIS I

1182
00:50:32,280 --> 00:50:35,120
APPRECIATE THE COMMENTS MADE

1183
00:50:35,120 --> 00:50:36,640
EARLIER AND WANTED TO KIND OF GO

1184
00:50:36,640 --> 00:50:41,000
BACK TO THE MAJOR POINT YOU WERE

1185
00:50:41,000 --> 00:50:43,680
MAKING.

1186
00:50:43,680 --> 00:50:45,000
HOW DO YOU STREAMLINE SERVICES

1187
00:50:45,000 --> 00:50:46,400
SO LOW AND MIDDLE COME INCOME

1188
00:50:46,400 --> 00:50:50,160
BACK SO MUCH TO USE THE

1189
00:50:50,160 --> 00:50:50,840
SERVICES.

1190
00:50:50,840 --> 00:50:52,920
I AGREE WITH THE LOCAL

1191
00:50:52,920 --> 00:50:54,480
DEVELOPMENT AND I HAVEN'T DONE

1192
00:50:54,480 --> 00:51:00,440
THIS WORK A WHILE BACK AND

1193
00:51:00,440 --> 00:51:02,520
THERE'S THE IDEA OF VOLUNTARY

1194
00:51:02,520 --> 00:51:03,720
COUPLES INVOLVED IN TESTING

1195
00:51:03,720 --> 00:51:07,000
SINCE A LOT OF YOUTH THEMSELVES

1196
00:51:07,000 --> 00:51:08,360
ARE ENGAGE IN A LOT OF WAYS AND

1197
00:51:08,360 --> 00:51:10,640
THE BIG PIECE OF THAT IS ALSO

1198
00:51:10,640 --> 00:51:11,720
MADE INVOLVEMENT BECAUSE A LOT

1199
00:51:11,720 --> 00:51:15,560
OF THE SERVICES AS YOU KNOW, IN

1200
00:51:15,560 --> 00:51:16,960
TERMS OF THE OTHER AREAS OF

1201
00:51:16,960 --> 00:51:25,120
TAKERS THAT IS MOSTLY I THINK

1202
00:51:25,120 --> 00:51:26,800
WHATEVER IS DONE, MAYBE SOME

1203
00:51:26,800 --> 00:51:28,520
EMPHASIZE ON MALE INVOLVEMENT

1204
00:51:28,520 --> 00:51:34,880
PARTICULARLY MALE PARTNERS IS

1205
00:51:34,880 --> 00:51:38,720
CRITICAL TO THE PROCESS IT'S

1206
00:51:38,720 --> 00:51:41,240
SELF AND THE IDEA OF THE

1207
00:51:41,240 --> 00:51:43,320
SCREENING IS WHAT I'M LOOKING

1208
00:51:43,320 --> 00:51:44,680
AT.

1209
00:51:44,680 --> 00:51:45,760
SCREENING FOR HIV AND MENTAL

1210
00:51:45,760 --> 00:51:49,960
HEALTH SERVICES AND THAT MIGHT

1211
00:51:49,960 --> 00:51:51,120
BE NEEDED THERE.

1212
00:51:51,120 --> 00:51:55,680
THERE'S THE WHOLE CHALLENGE OF

1213
00:51:55,680 --> 00:51:56,840
WORKFORCE ADEQUACY AND QUALITY.

1214
00:51:56,840 --> 00:51:58,440
WHO IS GOING TO DELIVER THIS.

1215
00:51:58,440 --> 00:52:00,160
I APPRECIATE THAT APPEAR

1216
00:52:00,160 --> 00:52:01,440
DELIVERY SYSTEM WOULD BE GOOD

1217
00:52:01,440 --> 00:52:03,640
HOWEVER THEY'RE NOT THE DECISION

1218
00:52:03,640 --> 00:52:05,240
MAKERS AND THE BIG PICTURE AND

1219
00:52:05,240 --> 00:52:06,880
THEY'RE NOT THOSE MOST LIKELY

1220
00:52:06,880 --> 00:52:09,320
THAT WILL WRITE THE PROPOSALS

1221
00:52:09,320 --> 00:52:10,840
AND GET THE GRANDS TO DO THIS SO

1222
00:52:10,840 --> 00:52:12,240
IT'S CRITICALLY IMPORTANT THAT

1223
00:52:12,240 --> 00:52:13,600
WHATEVER YOU DO, MY STRONG

1224
00:52:13,600 --> 00:52:17,120
SUGGESTION IS TO MAKE SURE

1225
00:52:17,120 --> 00:52:19,160
THERE'S IS SOME CLEARANCE OF

1226
00:52:19,160 --> 00:52:23,120
ADEQUACY IF NOT THEN SOME

1227
00:52:23,120 --> 00:52:24,720
SUPPORT FOR CAPACITY BUILDING TO

1228
00:52:24,720 --> 00:52:25,640
INVOLVED IN WHATEVER WORK THAT

1229
00:52:25,640 --> 00:52:26,720
YOU HAVE AS YOU KNOW PARTICULAR

1230
00:52:26,720 --> 00:52:27,720
IN THESE SETTINGS AND THAT IS

1231
00:52:27,720 --> 00:52:31,280
GOING TO BE A CHALLENGE IN ALL

1232
00:52:31,280 --> 00:52:32,360
KINDS OF DIFFERENT WAYS AND THE

1233
00:52:32,360 --> 00:52:34,360
LAST THING I WOULD SAY IT'S METH

1234
00:52:34,360 --> 00:52:37,200
LOGICAL APPROACH TO THIS AND ONE

1235
00:52:37,200 --> 00:52:38,800
OF THE THINGS WE LEARNED A VERY

1236
00:52:38,800 --> 00:52:40,320
LONG AGO IS THAT WE NEED MORE OF

1237
00:52:40,320 --> 00:52:43,800
A MIXED METHODOLOGY BOTH MIXED

1238
00:52:43,800 --> 00:52:45,720
DATA AND METHOT AS AN APPROACH

1239
00:52:45,720 --> 00:52:47,720
TO DEAL WITH THIS PARTICULARLY

1240
00:52:47,720 --> 00:52:54,000
BECAUSE OF THAT I WOULD SAY

1241
00:52:54,000 --> 00:52:55,080
GIVEN THE COUNTRIES YOU ARE

1242
00:52:55,080 --> 00:52:56,880
LOOKING AT WHERE A LOT OF THEM

1243
00:52:56,880 --> 00:53:07,400
ARE UNDER 30 AND SO THANK YOU

1244
00:53:13,240 --> 00:53:13,680
FOR THIS.

1245
00:53:13,680 --> 00:53:15,680
>>THANK YOU.

1246
00:53:15,680 --> 00:53:22,800
GO AHEAD.

1247
00:53:22,800 --> 00:53:24,160
JUST SOMETHING ELSE TO CONSIDER

1248
00:53:24,160 --> 00:53:30,000
WHICH IS, ARE YOU REALLY SEEKING

1249
00:53:30,000 --> 00:53:32,000
RESEARCH ON ANY LOW OR MIDDLE

1250
00:53:32,000 --> 00:53:35,040
INCOME COUNTRY OR MIGHT YOU NEED

1251
00:53:35,040 --> 00:53:35,880
A MORE DESCRIPTIVE REFERENCE TO

1252
00:53:35,880 --> 00:53:37,520
WHAT CONTEXT YOU ARE LOOKING FOR

1253
00:53:37,520 --> 00:53:41,840
AND ARE YOU LOOKING FOR PLACES

1254
00:53:41,840 --> 00:53:42,720
WITH HIGH MY PREVALENCE?

1255
00:53:42,720 --> 00:53:44,880
I THINK WE START TO USE LMICs

1256
00:53:44,880 --> 00:53:49,040
IN A WAY THAT DOESN'T

1257
00:53:49,040 --> 00:53:50,160
NECESSARILY MEAN SOMETHING AND

1258
00:53:50,160 --> 00:53:51,720
THERE MAY BE OTHERS THAN WORLD

1259
00:53:51,720 --> 00:53:53,000
BANK INCOME GROUPS THAT GET THE

1260
00:53:53,000 --> 00:54:00,280
KIND OF RESEARCH THAT YOU MIGHT

1261
00:54:00,280 --> 00:54:01,920
WANT AS YOU PREPARE FOR THAT.

1262
00:54:01,920 --> 00:54:02,360
>>THANK YOU.

1263
00:54:02,360 --> 00:54:08,800
>>DO YOU HAVE ANOTHER
QUESTION?

1264
00:54:08,800 --> 00:54:09,840
OF ANYONE ELSE?

1265
00:54:09,840 --> 00:54:10,840
>>OKAY.

1266
00:54:10,840 --> 00:54:13,880
FANTASTIC.

1267
00:54:13,880 --> 00:54:15,960
THANK YOU SO BOB, MIKE AND TERRY

1268
00:54:15,960 --> 00:54:18,320
AND THANK YOU ALL FOR YOUR

1269
00:54:18,320 --> 00:54:18,880
COMMENTS.

1270
00:54:18,880 --> 00:54:20,240
WE'RE A LITTLE AHEAD OF SCHEDULE

1271
00:54:20,240 --> 00:54:25,160
BUT WE CAN MOVE ON, RIGHT.

1272
00:54:25,160 --> 00:54:33,760
WE'LL DO A COMPUTER SWAP.

1273
00:54:33,760 --> 00:54:35,000
ARE SO CONTINUING OUR SLIGHTLY

1274
00:54:35,000 --> 00:54:37,120
OUT OF ORDER AGENDA FOR THE DAY

1275
00:54:37,120 --> 00:54:38,720
I WILL INTRODUCE OUR NEXT

1276
00:54:38,720 --> 00:54:40,440
SESSION THAT FOCUSES ON

1277
00:54:40,440 --> 00:54:42,240
IMPLEMENTATION OF THE NIH DATA

1278
00:54:42,240 --> 00:54:47,000
MANAGEMENT AND SHARING POLICY.

1279
00:54:47,000 --> 00:54:48,360
SO WE HAD A BRIEF DISCUSSION OF

1280
00:54:48,360 --> 00:54:50,280
THE NIH DATA MANAGEMENT SHARING

1281
00:54:50,280 --> 00:54:56,960
POLICY WHICH WENT INTO EFFECT

1282
00:54:56,960 --> 00:54:57,920
JANUARY 25th OF THIS YEAR AND

1283
00:54:57,920 --> 00:55:00,120
WE INVITED CREDIT DANIELSON AND

1284
00:55:00,120 --> 00:55:01,600
FROM THE NIH OFFICE OF

1285
00:55:01,600 --> 00:55:05,760
EXTRAMURAL RESEARCH AND TO

1286
00:55:05,760 --> 00:55:07,640
DISCUSS EVERYTHING ABOUT THE I

1287
00:55:07,640 --> 00:55:08,800
AMMENTED DATA MANAGEMENT SHARING

1288
00:55:08,800 --> 00:55:10,400
POLICY INTO ANSWER ANY QUESTIONS

1289
00:55:10,400 --> 00:55:12,160
THAT YOU MIGHT HAVE.

1290
00:55:12,160 --> 00:55:13,560
WE'RE ENCOURAGING YOU TO MAKE

1291
00:55:13,560 --> 00:55:14,720
THE MOST OF THE TIME WITH THEM

1292
00:55:14,720 --> 00:55:16,440
BECAUSE I'M SURE THAT MANY OF

1293
00:55:16,440 --> 00:55:18,040
YOUR COLLEAGUES AND THE RESEARCH

1294
00:55:18,040 --> 00:55:18,840
COMMUNITY ARE HOPING THAT YOU

1295
00:55:18,840 --> 00:55:20,800
WILL ASK ALL OF THE QUESTIONS

1296
00:55:20,800 --> 00:55:22,760
AND HAVE THIS ALL FIGURED OUT BY

1297
00:55:22,760 --> 00:55:28,800
THE TIME YOU LEAVE MEETING.

1298
00:55:28,800 --> 00:55:30,960
NIH HAS POSTED MANY GREAT

1299
00:55:30,960 --> 00:55:34,800
RESOURCES TO HELP GUIDE YOU AND

1300
00:55:34,800 --> 00:55:36,360
THE IMPLEMENTATION OF THIS

1301
00:55:36,360 --> 00:55:40,120
POLICY SO IF BEER READY, Dr.

1302
00:55:40,120 --> 00:55:41,360
DANIELSON AND SLEUTHMAN, THANK

1303
00:55:41,360 --> 00:55:42,680
YOU FOR BEING HERE.

1304
00:55:42,680 --> 00:55:43,960
WELCOME.

1305
00:55:43,960 --> 00:55:46,920
>>THANK YOU, VERY MUCH.

1306
00:55:46,920 --> 00:55:48,080
WHAT WE'RE HOPING TO DO DURING

1307
00:55:48,080 --> 00:55:49,160
THIS TIME WITH YOU IS TO GIVE

1308
00:55:49,160 --> 00:55:51,320
YOU A LITTLE BIT OF A BACKGROUND

1309
00:55:51,320 --> 00:55:57,960
ABOUT THE RATIONALE HOPEFULLY

1310
00:55:57,960 --> 00:56:03,200
THIS IS A LITTLE BIT BETTER.

1311
00:56:03,200 --> 00:56:04,720
IT SAYS IT'S ON BUT LET ME KNOW

1312
00:56:04,720 --> 00:56:05,960
IF I NEED TO SPEAK A LITTLE

1313
00:56:05,960 --> 00:56:07,560
MORE.

1314
00:56:07,560 --> 00:56:09,200
OUR PLAN IS TO GIVE YOU A BETTER

1315
00:56:09,200 --> 00:56:10,600
SENSE OF THE POLICY AND THE

1316
00:56:10,600 --> 00:56:11,960
REQUIREMENTS AND THE RATIONAL

1317
00:56:11,960 --> 00:56:13,680
AND THE PART OF DEVELOPING THE

1318
00:56:13,680 --> 00:56:15,440
POLICY AND THE TIMING OF THE

1319
00:56:15,440 --> 00:56:16,840
POLICY AND HOW WE'RE

1320
00:56:16,840 --> 00:56:18,240
IMPLEMENTING THE POLICY IN A

1321
00:56:18,240 --> 00:56:18,920
PARTICULAR HOW WE'RE LEARNING

1322
00:56:18,920 --> 00:56:21,000
FROM THE RESEARCH COMMUNITY AND

1323
00:56:21,000 --> 00:56:23,600
AS WE DO SO, AND THEN JUST SHARE

1324
00:56:23,600 --> 00:56:25,760
WITH YOU SOME RESOURCE THAT'S WE

1325
00:56:25,760 --> 00:56:27,560
HAVE AND SITUATE THE DISCUSSION

1326
00:56:27,560 --> 00:56:29,120
ABOUT DATA SHARING IS PART OF A

1327
00:56:29,120 --> 00:56:30,480
CULTURE CHANGE FOR NIH AS ONE OF

1328
00:56:30,480 --> 00:56:34,640
MANY FACTORS WITH CRITICAL ROLES

1329
00:56:34,640 --> 00:56:41,960
TO PLAY.

1330
00:56:41,960 --> 00:56:44,560
OIR FOCUS IS ON THE 2023 DATA

1331
00:56:44,560 --> 00:56:45,160
MANAGEMENT SHARING POLICY

1332
00:56:45,160 --> 00:56:47,080
HOWEVER THIS POLICY IS THE MOST

1333
00:56:47,080 --> 00:56:54,200
RECENT ONE IN A BROAD ECOSYSTEM

1334
00:56:54,200 --> 00:57:04,680
OF OF THE DMA POLICY REQUEST

1335
00:57:07,920 --> 00:57:09,600
RESISTS IN AN ECOSYSTEM WITH

1336
00:57:09,600 --> 00:57:15,000
OTHER POLICIES INCLUDING THE

1337
00:57:15,000 --> 00:57:15,800
CLINICAL TRIALS INFORMATION

1338
00:57:15,800 --> 00:57:21,320
POLICY AND NEXT SLIDE, PLEASE.

1339
00:57:21,320 --> 00:57:22,960
IN ADDITION TO THE POLICIES I

1340
00:57:22,960 --> 00:57:27,800
JUST MENTIONED THAT ARE CONVINCE

1341
00:57:27,800 --> 00:57:29,080
IMAGES TO USE THE AND PROGRAMS

1342
00:57:29,080 --> 00:57:30,200
MAY HAVE MANAGEMENT SHARING

1343
00:57:30,200 --> 00:57:32,720
POLICIES TO HELP PROVIDE AND

1344
00:57:32,720 --> 00:57:34,800
GUIDE APPLICANTS TO PARTICULAR

1345
00:57:34,800 --> 00:57:35,960
REPOSITORY AND THE BROADEN THE

1346
00:57:35,960 --> 00:57:46,400
SCOPE OF THE KINDS OF THIS IS A

1347
00:57:46,400 --> 00:57:47,800
SAMPLING OF POLICIES AND ICs

1348
00:57:47,800 --> 00:57:50,240
THAT HAVE EXISTING POLICIES

1349
00:57:50,240 --> 00:57:58,400
INCLUDING NIMH.

1350
00:57:58,400 --> 00:58:00,480
SO WHY IN THIS BROAD ECOSYSTEM

1351
00:58:00,480 --> 00:58:01,960
WITH MANY POLICIES FOR RESEARCH

1352
00:58:01,960 --> 00:58:03,320
AND INSTITUTIONS TO RESPOND TO

1353
00:58:03,320 --> 00:58:06,360
AND BE COMPLIANT WITH NIMH

1354
00:58:06,360 --> 00:58:10,560
ROLLED OUT A NEW DATA SHARING

1355
00:58:10,560 --> 00:58:14,760
POLICY.

1356
00:58:14,760 --> 00:58:17,000
RESEARCHERS HAVE TRIED TO

1357
00:58:17,000 --> 00:58:18,840
REQUEST BASED ON POLICY AND

1358
00:58:18,840 --> 00:58:23,400
PUBLICATIONS AND ACCESS TO

1359
00:58:23,400 --> 00:58:25,120
PUBLICATIONS AND WHAT WHAT IS

1360
00:58:25,120 --> 00:58:28,040
COMMON IS THE RATE OF ACTUALLY

1361
00:58:28,040 --> 00:58:33,760
RECEIVING BACK DATA THAT WAS

1362
00:58:33,760 --> 00:58:41,920
SAID TO BE SHARED PRODUCE

1363
00:58:41,920 --> 00:58:43,960
STUDIES DESPITE THE EXISTENCE OF

1364
00:58:43,960 --> 00:58:49,200
MULTIPLE SHARING POLICIES.

1365
00:58:49,200 --> 00:58:51,000
NEXT SLIDE, PLEASE IN ADDITION

1366
00:58:51,000 --> 00:58:53,000
TO CHARGES FOR RESEARCHERS AND

1367
00:58:53,000 --> 00:58:56,120
ACTIVE COMMUNITY AND ACCESSING

1368
00:58:56,120 --> 00:58:57,840
EXISTING DATA, ACCESS TO DATA

1369
00:58:57,840 --> 00:59:02,800
AND AVAILABILITY OF ESTIMATE AND

1370
00:59:02,800 --> 00:59:04,880
SO THIS SLIDE SHOWS DATA FROM A

1371
00:59:04,880 --> 00:59:08,120
FEW RESEARCH STUDY WHICH ASKED

1372
00:59:08,120 --> 00:59:12,400
MEMBERS OF THE PUBLIC WHAT OUR

1373
00:59:12,400 --> 00:59:14,600
FACTORS IN ENHANCING THE TRUST

1374
00:59:14,600 --> 00:59:16,640
OF SCIENTIFIC DATA AND THE

1375
00:59:16,640 --> 00:59:19,240
FACTOR THAT THE GREATEST PORTION

1376
00:59:19,240 --> 00:59:20,760
OF THOSE RESPONDING TO THE

1377
00:59:20,760 --> 00:59:25,360
SURVEY SPENDED TO 57% IS THE

1378
00:59:25,360 --> 00:59:27,000
DATA IS OPENLY AVAILABLE TO THE

1379
00:59:27,000 --> 00:59:27,800
PUBLIC SO AGAIN UNDER SCORING

1380
00:59:27,800 --> 00:59:33,800
THE NEED FOR REALLY ROBUST AND

1381
00:59:33,800 --> 00:59:34,640
MEANINGFUL OF PRACTICES FOR DATA

1382
00:59:34,640 --> 00:59:35,000
SHARING.

1383
00:59:35,000 --> 00:59:45,320
NEXT SLIDE, PLEASE.

1384
00:59:59,960 --> 01:00:02,520
IT INVOLVED MANY GROUPS INVOLVED

1385
01:00:02,520 --> 01:00:03,440
TITLE CONSULTATIONS AND IT

1386
01:00:03,440 --> 01:00:05,720
INVOLVED FEEDBACK FROM SOME

1387
01:00:05,720 --> 01:00:07,560
EXISTING COMMITTEES FOCUSED ON

1388
01:00:07,560 --> 01:00:09,640
PROTECTION AND INCLUDING THE

1389
01:00:09,640 --> 01:00:10,240
SECRETARIES ADVISORY COMMITTEE

1390
01:00:10,240 --> 01:00:11,680
FOR HUMAN RESEARCH PROTECTION

1391
01:00:11,680 --> 01:00:14,560
AND OTHER AGENCIES.

1392
01:00:14,560 --> 01:00:16,240
THE POLICY ITSELF WAS RELEASED

1393
01:00:16,240 --> 01:00:18,640
AND PUBLISHED IN 2020 AND WENT

1394
01:00:18,640 --> 01:00:22,720
INTO EFFECT ON JANUARY 25th,

1395
01:00:22,720 --> 01:00:32,280
2023.

1396
01:00:32,280 --> 01:00:42,840
THE FIRST OF THESE IS TO ADVANCE

1397
01:00:49,280 --> 01:00:51,880
IT IT'S RESTORATIVE DATA AND

1398
01:00:51,880 --> 01:00:53,000
RESEARCH PUBLIC TRUST IN

1399
01:00:53,000 --> 01:00:56,560
RESEARCH FOR A NUMBER OF

1400
01:00:56,560 --> 01:01:06,720
REASONS.

1401
01:01:21,320 --> 01:01:23,120
S IS LET ME TELL BUT THE SCOPE

1402
01:01:23,120 --> 01:01:24,720
AND THE POLICY.

1403
01:01:24,720 --> 01:01:29,720
THE POLICY REALLY HAS ONLY TO

1404
01:01:29,720 --> 01:01:31,920
REQUIRE THEY SUBMIT A DATA

1405
01:01:31,920 --> 01:01:42,400
MANAGEMENT AND SHARING PLAN IS

1406
01:01:47,320 --> 01:01:48,440
AND THE DEFINITION OF WHAT IS

1407
01:01:48,440 --> 01:01:52,760
MEANT BY SCIENTIFIC DATA AND

1408
01:01:52,760 --> 01:01:55,800
WITH FACTUAL QUALITY TO VALIDATE

1409
01:01:55,800 --> 01:01:57,640
REPLICATE RESEARCH FINDING AND

1410
01:01:57,640 --> 01:01:59,600
THIS IS REGARDLESS OF WHETHER

1411
01:01:59,600 --> 01:02:03,160
DATA UNDERLIES PUBLICATIONS OR

1412
01:02:03,160 --> 01:02:04,800
WEATHER DATA IS NOT USED IN

1413
01:02:04,800 --> 01:02:05,920
PUBLICATIONS AND IMPORTANTLY

1414
01:02:05,920 --> 01:02:12,160
WHAT THE SCOPE DOES NOT INCLUDE

1415
01:02:12,160 --> 01:02:13,720
IS OTHER DATA AND PHYSICAL

1416
01:02:13,720 --> 01:02:16,840
OBJECTION INCLUDING BIO SIS ONLY

1417
01:02:16,840 --> 01:02:17,520
TO DATA.

1418
01:02:17,520 --> 01:02:19,240
THE POLICY ALSO DESCRIBES TIME

1419
01:02:19,240 --> 01:02:21,960
LINES FOR SHARING DATA AND SO

1420
01:02:21,960 --> 01:02:24,000
DATA IS REQUIRED TO BE SHARED NO

1421
01:02:24,000 --> 01:02:26,920
LATER THAN THE DATE OF PUB WILL

1422
01:02:26,920 --> 01:02:29,360
INDICATION FOR A PRIMARY WILL

1423
01:02:29,360 --> 01:02:31,000
YOU BE LA INDICATION OR THE END

1424
01:02:31,000 --> 01:02:32,920
OF THE PERFORMANCE PERIOD FOR

1425
01:02:32,920 --> 01:02:35,440
DATA THAT DOESN'T UNDERLINE

1426
01:02:35,440 --> 01:02:36,400
PUBLICATIONS WHICH EVER OF THOSE

1427
01:02:36,400 --> 01:02:40,240
TWO POINTS IN TIMES COMES FIRST.

1428
01:02:40,240 --> 01:02:42,280
IT ALLOWS A LOT OF FLEXIBILITY

1429
01:02:42,280 --> 01:02:44,840
WITH REGARD TO HOW LONG DATA

1430
01:02:44,840 --> 01:02:47,080
SHOULD BE SCARED AND MAINTAINED

1431
01:02:47,080 --> 01:02:49,600
AND REALLY ENCOURAGING

1432
01:02:49,600 --> 01:02:52,880
RESEARCHERS TO CONSULT WITH ZOO

1433
01:02:52,880 --> 01:02:54,640
OTHER GROUPS TO THINK ABOUT

1434
01:02:54,640 --> 01:02:55,920
OTHER REQUIREMENTS AND

1435
01:02:55,920 --> 01:02:57,080
EXPECTATIONS AND JOURNAL

1436
01:02:57,080 --> 01:02:58,280
POLICIES, REPOSITORY POLICIES

1437
01:02:58,280 --> 01:02:59,880
AND THEIR OWN INSTITUTION

1438
01:02:59,880 --> 01:03:01,280
POLICIES FOR MAINTAINING

1439
01:03:01,280 --> 01:03:10,440
RESEARCH RECORDS AND DATA.

1440
01:03:10,440 --> 01:03:11,920
IT THERE'S MORE INFORMATION

1441
01:03:11,920 --> 01:03:12,960
ABOUT WHICH ACTIVITY CODES IN

1442
01:03:12,960 --> 01:03:15,040
PARTICULAR THE POLICY IS

1443
01:03:15,040 --> 01:03:15,600
APPLICABLE TO.

1444
01:03:15,600 --> 01:03:17,320
IN GENERAL THE POLICY APPLIES AS

1445
01:03:17,320 --> 01:03:20,680
I SAID, TO RESEARCH THAT

1446
01:03:20,680 --> 01:03:22,280
GENERATES SCIENTIFIC DATA SO

1447
01:03:22,280 --> 01:03:24,440
RESEARCH PROJECTS, AND SMALL

1448
01:03:24,440 --> 01:03:34,840
BUSINESS AWARDS AS WELL.

1449
01:03:40,080 --> 01:03:41,680
THERE'S A DETAIL LISTING OF ALL

1450
01:03:41,680 --> 01:03:42,600
ACTIVITIES CODES SO IT'S

1451
01:03:42,600 --> 01:03:43,760
POSSIBLE FOR APPLICANTS TO LOOK

1452
01:03:43,760 --> 01:03:45,360
AT THE PARTICULAR ACTIVITY CODES

1453
01:03:45,360 --> 01:03:46,200
WHICH THEY'RE CONSIDERING TO

1454
01:03:46,200 --> 01:03:50,000
UNDERSTAND THE POLICIES

1455
01:03:50,000 --> 01:03:58,120
APPLICABLEAPPLICABILITY.

1456
01:03:58,120 --> 01:03:59,560
IT'S ADDITIONAL EXPECTATIONS FOR

1457
01:03:59,560 --> 01:04:00,480
DATA MANAGEMENT AND SHARING

1458
01:04:00,480 --> 01:04:03,640
PLANS.

1459
01:04:03,640 --> 01:04:14,120
SO THE FIRST SO PLANS SHOULD

1460
01:04:38,560 --> 01:04:42,200
OUTLINE SHARING AND OUTLINE HOW

1461
01:04:42,200 --> 01:04:45,840
PROTECTION OF PRIVACY RIGHTS AND

1462
01:04:45,840 --> 01:04:47,520
CONFIDENTIALITY AND MAINTAINED

1463
01:04:47,520 --> 01:04:49,520
AND DESCRIBE ANY EXISTING LAWS

1464
01:04:49,520 --> 01:04:50,880
OR REGULATIONS THAT MIGHT APPLY

1465
01:04:50,880 --> 01:04:55,760
AND IT MIGHT LIMITS TO DATA

1466
01:04:55,760 --> 01:05:05,880
SHARING.

1467
01:05:08,280 --> 01:05:09,640
THINKING ABOUT WHAT INFORMATION

1468
01:05:09,640 --> 01:05:10,800
IS CONVEYED AND WHAT WE SHARED

1469
01:05:10,800 --> 01:05:14,080
AND SECONDARY DATA SHARING AND

1470
01:05:14,080 --> 01:05:16,720
ADDITIONALLY, THE POLICY AT NIH

1471
01:05:16,720 --> 01:05:18,520
ENCOURAGES INVESTIGATORS TO

1472
01:05:18,520 --> 01:05:20,280
THINK ABOUT THEIR PLANS FOR DATA

1473
01:05:20,280 --> 01:05:22,360
SUBMISSION AND WHAT ARE THE

1474
01:05:22,360 --> 01:05:23,760
REPOSITORIES AND THE PROTECTIONS

1475
01:05:23,760 --> 01:05:27,400
IN THOSE REPOSITORY FOR OTHER

1476
01:05:27,400 --> 01:05:28,560
LOCATIONS FOR RESTORING DATA AND

1477
01:05:28,560 --> 01:05:30,960
WITH REGARD TO CONTROLS FOR DATA

1478
01:05:30,960 --> 01:05:32,360
ACCESS SO DATA SHOULD BE STORED

1479
01:05:32,360 --> 01:05:35,800
ISTORED IN A CONTROLLED FASHION

1480
01:05:35,800 --> 01:05:37,200
AND THINKING THROUGH IN A

1481
01:05:37,200 --> 01:05:39,000
THOROUGH WAY THAT WE HAVE PLANS

1482
01:05:39,000 --> 01:05:48,320
FOR SUBMITTING AND STORING DATA.

1483
01:05:48,320 --> 01:05:49,720
THE POLICY ALLOWS FOR

1484
01:05:49,720 --> 01:05:50,680
APPROPRIATE ETHICAL AND LEGAL

1485
01:05:50,680 --> 01:05:52,440
ASK TECHNICAL FACTORS FOR

1486
01:05:52,440 --> 01:05:56,320
ELIMINATION OF DATA AND WE HAVE

1487
01:05:56,320 --> 01:05:58,360
A FREQUENT ASKED QUESTIONS ABOUT

1488
01:05:58,360 --> 01:05:59,600
RESOURCES TO SUPPORT APPLICANTS

1489
01:05:59,600 --> 01:06:03,080
AND COMPLY WITH THE POLICY THAT

1490
01:06:03,080 --> 01:06:04,600
GETS SPECIFIC EXAMPLES OF WHAT

1491
01:06:04,600 --> 01:06:06,760
FACTORS NIH HAS IN MIND SO THESE

1492
01:06:06,760 --> 01:06:08,480
EXAMPLES INCLUDE, OBVIOUSLY THIS

1493
01:06:08,480 --> 01:06:12,440
IS MY COMPREHENSIVE SITUATIONS

1494
01:06:12,440 --> 01:06:14,080
WHERE THEY WILL NOT PERMIT OR

1495
01:06:14,080 --> 01:06:16,600
HAS ON THE SCOPE OF DATA SHARING

1496
01:06:16,600 --> 01:06:19,640
AND DATA REVIEWS AND

1497
01:06:19,640 --> 01:06:21,800
ADDITIONALLY, OTHER EXISTING FED

1498
01:06:21,800 --> 01:06:23,400
CAL STATE TRAVEL LAWS OR

1499
01:06:23,400 --> 01:06:24,440
REGULATION STATE LAWS AND THE

1500
01:06:24,440 --> 01:06:27,160
PARTICULAR CONCEPT DISCLOSURE OR

1501
01:06:27,160 --> 01:06:30,640
SHARING BUT ALSO THE LEGAL

1502
01:06:30,640 --> 01:06:32,400
FACTORS FOR LIMITING DATA USE.

1503
01:06:32,400 --> 01:06:34,560
THE KINDS OF REASONS THAT

1504
01:06:34,560 --> 01:06:35,520
CURRENT CONSIDERED TO BE

1505
01:06:35,520 --> 01:06:37,480
JUSTIFIABLE FOR LIMITED DATA

1506
01:06:37,480 --> 01:06:39,200
SHARING INCLUDE CONSIDERATIONS

1507
01:06:39,200 --> 01:06:40,800
THAT MAY BE A DATASET IS TOO

1508
01:06:40,800 --> 01:06:42,000
SMALL TO BE OF VALUE AND

1509
01:06:42,000 --> 01:06:44,200
RESEARCHERS THINK THAT THE DATA

1510
01:06:44,200 --> 01:06:46,080
MAY NOT BE USEFUL TO

1511
01:06:46,080 --> 01:06:48,360
COLLABORATORS AND THERE'S NOT AN

1512
01:06:48,360 --> 01:06:49,840
APPROPRIATE REPOSITORY FOR

1513
01:06:49,840 --> 01:06:51,600
MOUSING THE DATA SO THOSE ARE

1514
01:06:51,600 --> 01:06:53,960
EXISTED AND OUR THOUGHTS TO BE

1515
01:06:53,960 --> 01:06:54,880
JUSTIFIABLE AND I WILL MENTION

1516
01:06:54,880 --> 01:06:57,960
THAT WE DO HAVE A GUIDE THAT

1517
01:06:57,960 --> 01:07:00,720
TALKS ABOUT SELECTION OF ROBUST

1518
01:07:00,720 --> 01:07:02,680
REPOSITORY AND CHARACTERISTICS

1519
01:07:02,680 --> 01:07:07,160
AS WELL AS A NUMBER OF RESOURCES

1520
01:07:07,160 --> 01:07:09,000
ON THE SHARING AT NIH.GOV

1521
01:07:09,000 --> 01:07:12,200
WEBSITE WITH EXPEL OF OTHER

1522
01:07:12,200 --> 01:07:15,560
SPECIALIST GENERALIST

1523
01:07:15,560 --> 01:07:19,160
REPOSITORIES.

1524
01:07:19,160 --> 01:07:23,480
WE HAVE A NUMBER OF FAQs AND

1525
01:07:23,480 --> 01:07:24,720
RESOURCES FOR SUPPORTING

1526
01:07:24,720 --> 01:07:29,120
APPLICANTS AS THEY PREPARE PLANS

1527
01:07:29,120 --> 01:07:30,880
AND COMPLY WITH THE POLICY AND

1528
01:07:30,880 --> 01:07:32,520
WE HAVE A LARGE NUMBER OF FAQs

1529
01:07:32,520 --> 01:07:36,520
AND POLICIES INCLUDING ONE AREA

1530
01:07:36,520 --> 01:07:38,720
NA IS NOT AND IT'S BUDGET SO WE

1531
01:07:38,720 --> 01:07:39,520
RECEIVED MANY QUESTIONS ABOUT

1532
01:07:39,520 --> 01:07:42,600
HOW TO CONSIDER AND BUDGET FOREL

1533
01:07:42,600 --> 01:07:44,600
POLICY AND HAVE 13FAQs RELATED

1534
01:07:44,600 --> 01:07:45,920
TO THAT AS WELL SO I ENCOURAGE

1535
01:07:45,920 --> 01:07:51,960
YOU TO EXPLORE THE SHARING

1536
01:07:51,960 --> 01:07:52,840
WEBSITE AND CONSIDER THESE IN

1537
01:07:52,840 --> 01:07:56,200
DEVELOPING DATA MANAGEMENT AND

1538
01:07:56,200 --> 01:07:56,560
SHARING PLANS.

1539
01:07:56,560 --> 01:08:00,200
NEXT SLIDE, PLEASE.

1540
01:08:00,200 --> 01:08:02,600
SO, VERY BRIEFLY JUST TO GIVE A

1541
01:08:02,600 --> 01:08:04,200
FLAVOR OF HOW THE POLICY IS

1542
01:08:04,200 --> 01:08:09,520
BEING IMPLEMENTED AND WHAT THE

1543
01:08:09,520 --> 01:08:10,440
WORKFLOW LOOKS LIKE FOR

1544
01:08:10,440 --> 01:08:12,200
APPLICANTS AS THEY PUT TOGETHER

1545
01:08:12,200 --> 01:08:13,920
A DATA MANAGEMENT PLAN AS PART

1546
01:08:13,920 --> 01:08:15,600
OF THEIR APPLICATIONS.

1547
01:08:15,600 --> 01:08:18,360
WHAT THE APPLICATION, THE DATA

1548
01:08:18,360 --> 01:08:19,800
MANAGEMENT AND PLAN IS

1549
01:08:19,800 --> 01:08:23,720
SUBMITTED, ADDITIONALLY, A BRIEF

1550
01:08:23,720 --> 01:08:27,200
BUDGET JUSTIFICATION IS ALSO

1551
01:08:27,200 --> 01:08:29,040
SUBMITTED.

1552
01:08:29,040 --> 01:08:30,560
PEER REVIEWERS WILL NOT HAVE

1553
01:08:30,560 --> 01:08:32,080
ACCESS TO THE DATA MANAGEMENT

1554
01:08:32,080 --> 01:08:33,600
AND SHARING PLAN ITSELF, THEY

1555
01:08:33,600 --> 01:08:35,280
WILL SEE THE BRIEF BUDGET

1556
01:08:35,280 --> 01:08:36,360
JUSTIFICATION AND THE BUDGET

1557
01:08:36,360 --> 01:08:38,200
THAT'S PROVIDED.

1558
01:08:38,200 --> 01:08:39,160
THE ASSESSMENT OF DATA

1559
01:08:39,160 --> 01:08:40,880
MANAGEMENT SHARING PLANS IS

1560
01:08:40,880 --> 01:08:44,560
RESPONSIBILITY OF NIH PROGRAMS

1561
01:08:44,560 --> 01:08:47,000
STAFF.

1562
01:08:47,000 --> 01:08:48,400
OF IN THE APPLICATION,

1563
01:08:48,400 --> 01:08:49,960
SUBMISSION AND REVIEW PROCESS AS

1564
01:08:49,960 --> 01:08:51,560
WELL AS DURING THE LIFE CYCLE OF

1565
01:08:51,560 --> 01:08:58,120
THE AWARD.

1566
01:08:58,120 --> 01:08:59,840
OF THE CONTENT OF THE DMS PLANS

1567
01:08:59,840 --> 01:09:02,480
ARE IN THE TERMS OF CONDITIONS

1568
01:09:02,480 --> 01:09:04,720
OF THE AWARD AND NIH STAFF WILL

1569
01:09:04,720 --> 01:09:06,080
MONITOR COMPLIANCE OF THE PLANS

1570
01:09:06,080 --> 01:09:09,200
AT WEG REPORTING INTERVALS

1571
01:09:09,200 --> 01:09:10,320
ANNUALLY.

1572
01:09:10,320 --> 01:09:12,520
FINALLY, A COMPLIANCE OR LACK

1573
01:09:12,520 --> 01:09:15,400
THERE OF MAY FACTOR INTO FUTURE

1574
01:09:15,400 --> 01:09:17,320
DIVISIONS AND I'LL TURN THE

1575
01:09:17,320 --> 01:09:19,920
PRESENTATION OVER TO Dr.

1576
01:09:19,920 --> 01:09:20,160
DANIELSON.

1577
01:09:20,160 --> 01:09:24,360
>>THANK YOU, NEXT SLIDE,

1578
01:09:24,360 --> 01:09:26,360
PLEASE.

1579
01:09:26,360 --> 01:09:29,200
>>SO CONTINUING WITH THE
PUBLIC

1580
01:09:29,200 --> 01:09:29,800
ENGAGEMENT WE HAVE CONTINUED

1581
01:09:29,800 --> 01:09:31,840
THAT IN TERMS OF IMPLEMENTATION

1582
01:09:31,840 --> 01:09:33,360
OVER THE LAST COUPLE OF YEARS

1583
01:09:33,360 --> 01:09:35,440
AND ENGAGING IN PUBLIC OUTREACH

1584
01:09:35,440 --> 01:09:36,480
AND EDUCATION.

1585
01:09:36,480 --> 01:09:38,800
AND THIS IS REALLY A TWO-DAY

1586
01:09:38,800 --> 01:09:39,960
CONVERSATION SO WE'RE PROVIDING

1587
01:09:39,960 --> 01:09:41,680
INFORMATION AND RESOURCES TO

1588
01:09:41,680 --> 01:09:43,400
HELP PREPARING THE COMMUNITY FOR

1589
01:09:43,400 --> 01:09:48,360
THIS POLICY AND ALSO TO HEAR THE

1590
01:09:48,360 --> 01:09:49,760
QUESTION AND FEEDBACK AND ON

1591
01:09:49,760 --> 01:09:50,720
THIS SLIDE HERE YOU ARE SEEING A

1592
01:09:50,720 --> 01:09:52,000
SELECTION OF RECENT

1593
01:09:52,000 --> 01:09:53,480
PRESENTATIONS AND GIVEN TO

1594
01:09:53,480 --> 01:09:56,160
VARIOUS GROUPS AND SO

1595
01:09:56,160 --> 01:09:56,680
INSTITUTIONS, RESEARCHERS,

1596
01:09:56,680 --> 01:09:57,800
SCIENTIFIC ASSOCIATIONS AND AS

1597
01:09:57,800 --> 01:10:00,080
WELL AS OTHER GROUPS, AND WE'RE

1598
01:10:00,080 --> 01:10:01,440
ALSO WANTING TO HIGHLIGHT

1599
01:10:01,440 --> 01:10:02,800
SPECIFIC EVENTS WITH A LARGER

1600
01:10:02,800 --> 01:10:04,880
REACH AND RECENTLY THAT WAS THE

1601
01:10:04,880 --> 01:10:06,960
NIH GRANTS CONFERENCE AND WHERE

1602
01:10:06,960 --> 01:10:09,040
NOT WE REACHED OVER 2,000

1603
01:10:09,040 --> 01:10:11,400
ATTENDEES OF THE LIVE SESSION

1604
01:10:11,400 --> 01:10:12,880
AND THEN THIS PAST SUMMER, WE

1605
01:10:12,880 --> 01:10:16,120
HAD A MORE EXTENSIVE TWO-PART

1606
01:10:16,120 --> 01:10:17,400
WEBINAR SERIES JUST FOCUSING ON

1607
01:10:17,400 --> 01:10:19,120
THIS POLICY AND COVERING THE

1608
01:10:19,120 --> 01:10:20,840
NUMBER OF TOPICS AND QUESTIONS

1609
01:10:20,840 --> 01:10:24,920
THAT WE SEE DURING THOSE

1610
01:10:24,920 --> 01:10:26,200
SESSIONS.

1611
01:10:26,200 --> 01:10:27,680
HAD SO THIS OUTREACH HAS ALLOWED

1612
01:10:27,680 --> 01:10:29,760
US TO HEAR FIRSTHAND WHERE THE

1613
01:10:29,760 --> 01:10:30,960
COMMUNITY SEES THE NEED FOR

1614
01:10:30,960 --> 01:10:32,120
ADDITIONAL RESOURCES.

1615
01:10:32,120 --> 01:10:33,920
AND WE REALLY ARE IN LEARNING

1616
01:10:33,920 --> 01:10:37,240
MODE WHILE THIS POLICY IS SO NEW

1617
01:10:37,240 --> 01:10:38,760
AND WE'RE MAKING SURE TO BE

1618
01:10:38,760 --> 01:10:39,600
RESPONSIVE TO THE COMMUNITY WITH

1619
01:10:39,600 --> 01:10:41,200
WHAT THEY SEE AS ADDITIONAL

1620
01:10:41,200 --> 01:10:43,200
NEEDS TO BE PREPARED FOR THIS

1621
01:10:43,200 --> 01:10:43,640
POLICY.

1622
01:10:43,640 --> 01:10:46,040
AS SAN EXAMPLE OF THAT IN

1623
01:10:46,040 --> 01:10:46,720
RESPONSE TO FREQUENT QUESTIONS

1624
01:10:46,720 --> 01:10:52,800
ABOUT WHAT FORMAT SHOULD BE USED

1625
01:10:52,800 --> 01:10:55,520
NIH CREATED AN OPENINGAL FORMAT

1626
01:10:55,520 --> 01:10:56,960
PAGE TO GIVE PEOPLE SOMEWHERE TO

1627
01:10:56,960 --> 01:10:59,160
START AND IN TERMS OF THE FORMAT

1628
01:10:59,160 --> 01:11:01,520
PAGE IT ALLOWS WITH THE ELEMENTS

1629
01:11:01,520 --> 01:11:03,600
OF A DMS PLANS THAT WAS

1630
01:11:03,600 --> 01:11:08,560
PUBLISHED ALONGSIDE THE POLICY

1631
01:11:08,560 --> 01:11:10,080
ITSELF, IT SPLITS IT UP TO HELP

1632
01:11:10,080 --> 01:11:11,040
WITH DIFFERENT PIECES OF

1633
01:11:11,040 --> 01:11:14,720
INFORMATION THAT MIGHT BE

1634
01:11:14,720 --> 01:11:25,280
RELEVANT TO OF COVERING THE MANY

1635
01:11:26,640 --> 01:11:27,600
DIFFERENT AREAS OF SCIENCE AND

1636
01:11:27,600 --> 01:11:29,680
NIH SUPPORTS AND WE WANT TO

1637
01:11:29,680 --> 01:11:30,960
LEARN WHAT WORKS BEST FOR

1638
01:11:30,960 --> 01:11:36,680
DIFFERENT SCIENCE AND PROJECTS

1639
01:11:36,680 --> 01:11:37,840
AND AND WE ARE LEARNING FROM THE

1640
01:11:37,840 --> 01:11:40,040
COMMUNITY IS BY ENGAGING IN A

1641
01:11:40,040 --> 01:11:42,800
PILOT PROJECT WITH THE FED CAL

1642
01:11:42,800 --> 01:11:43,400
DEMONSTRATION PARTNERSHIP TO

1643
01:11:43,400 --> 01:11:45,280
TEST OUT DIFFERENT APPROACHES

1644
01:11:45,280 --> 01:11:48,760
NEXT SLIDE, PLEASE.

1645
01:11:48,760 --> 01:11:50,160
SO THROUGH A COLLABORATION

1646
01:11:50,160 --> 01:11:53,120
BETWEEN THE FDP AND NIH THIS

1647
01:11:53,120 --> 01:11:56,000
PILOT PROJECT IS TESTING THE

1648
01:11:56,000 --> 01:11:57,280
EFFECTIVENESS AND USABILITY OF

1649
01:11:57,280 --> 01:12:01,680
TWO TEMPLATES FOR DMS PLANS AND

1650
01:12:01,680 --> 01:12:03,160
ONE PART IS GETTING FEEDBACK

1651
01:12:03,160 --> 01:12:05,880
FROM THE RESEARCHER AND FACULTY

1652
01:12:05,880 --> 01:12:06,920
PERSPECTIVE FROM THOSE

1653
01:12:06,920 --> 01:12:07,880
DEVELOPING THESE PLANS AND ALSO

1654
01:12:07,880 --> 01:12:10,040
GETTING FEEDBACK FROM THE NIH

1655
01:12:10,040 --> 01:12:11,600
PROGRAM PROSPECTIVE AS THEY'RE

1656
01:12:11,600 --> 01:12:14,200
THE RUNS TO ASSESS THESE PLANS

1657
01:12:14,200 --> 01:12:16,800
AND THIS PROJECT IS JUST KICKED

1658
01:12:16,800 --> 01:12:18,560
OFF RECENTLY AND WE'RE REALLY

1659
01:12:18,560 --> 01:12:22,280
LOOKING FORWARD TO GETTING MORE

1660
01:12:22,280 --> 01:12:23,920
INFORMATION AND IS TAKING THIS

1661
01:12:23,920 --> 01:12:25,480
INTO ACCOUNT AS WE LOOK AT WHAT

1662
01:12:25,480 --> 01:12:26,440
RESOURCES AND CHANGES MIGHT BE

1663
01:12:26,440 --> 01:12:27,600
NEEDED IN THE FUTURE.

1664
01:12:27,600 --> 01:12:29,760
THERE'S A SECOND FACE OF THE FDP

1665
01:12:29,760 --> 01:12:31,320
PILOT THAT WILL FOCUS ON COST

1666
01:12:31,320 --> 01:12:32,680
AND THIS KEEPS IN MINDS

1667
01:12:32,680 --> 01:12:33,360
QUESTIONS WE'VE BEEN HEARING

1668
01:12:33,360 --> 01:12:34,680
FROM THE COMMUNITY AND AS THEY

1669
01:12:34,680 --> 01:12:36,320
CONSIDER WHAT TYPES OF COSTS ARE

1670
01:12:36,320 --> 01:12:38,560
REQUIRED TO MANAGE AND SHARE

1671
01:12:38,560 --> 01:12:40,360
THEIR DATA AND ACCORDANCE WITH

1672
01:12:40,360 --> 01:12:41,800
THE PLANS OF THEIR DEVELOPING.

1673
01:12:41,800 --> 01:12:45,280
NEXT SLIDE, PLEASE.

1674
01:12:45,280 --> 01:12:47,000
ANOTHER EXAMPLE OF LISTEN TO GO

1675
01:12:47,000 --> 01:12:49,120
THE COMMUNITY TO HELP TARGET OUR

1676
01:12:49,120 --> 01:12:53,160
IMPLEMENTATION EFFORTS IS SAMPLE

1677
01:12:53,160 --> 01:12:56,160
PLANS.

1678
01:12:56,160 --> 01:12:57,680
AND THEY HAVE BEEN COMPLETED FOR

1679
01:12:57,680 --> 01:12:58,960
EDUCATIONAL PURPOSES HOW SUCH A

1680
01:12:58,960 --> 01:13:00,480
PLAN COULD BE COMPLETED IN

1681
01:13:00,480 --> 01:13:01,600
DIFFERENT CONTEXT AND OF COURSE

1682
01:13:01,600 --> 01:13:04,200
IT'S NOT A ONE-SIZE-FITS-ALL,

1683
01:13:04,200 --> 01:13:06,240
TYPE OF FORMAT IT REALLY WILL

1684
01:13:06,240 --> 01:13:08,120
VARY DEPENDING ON WHAT TYPE OF

1685
01:13:08,120 --> 01:13:09,240
SCIENCE YOU ARE CONDUCTING AND

1686
01:13:09,240 --> 01:13:11,320
WHAT TYPE OF DATA YOU ARE

1687
01:13:11,320 --> 01:13:13,440
GENERATING AND WE HAVE NOW

1688
01:13:13,440 --> 01:13:15,880
NUMBER OF PLANS THAT ARE HELPFUL

1689
01:13:15,880 --> 01:13:16,920
RESOURCE TO TAKE A LOOK AT AND

1690
01:13:16,920 --> 01:13:19,080
SEE HOW THIS MIGHT BE DONE AND

1691
01:13:19,080 --> 01:13:21,840
SO WE'RE VERY GRATEFUL TO OUR

1692
01:13:21,840 --> 01:13:23,240
COLLEAGUES WHO HAVE LED THE WAY

1693
01:13:23,240 --> 01:13:24,880
HERE AND THEY DEVELOPED THE

1694
01:13:24,880 --> 01:13:26,800
FIRST BATCH OF NIH SAMPLE PLAN

1695
01:13:26,800 --> 01:13:28,640
SPECIFIC TO THE AREAS OF SCIENCE

1696
01:13:28,640 --> 01:13:30,920
AND TYPES OF DATA COMMONLY

1697
01:13:30,920 --> 01:13:33,440
GENERATED THROUGH SUPPORT AND

1698
01:13:33,440 --> 01:13:34,800
SINCE THEN WE'VE ADDED SAMPLE

1699
01:13:34,800 --> 01:13:36,880
PLANS FROM OTHER NIH INSTITUTES

1700
01:13:36,880 --> 01:13:39,720
AND CENTERS SO WE ARE HAVING A

1701
01:13:39,720 --> 01:13:40,880
RANGE OF DIFFERENT EXAMPLES TO

1702
01:13:40,880 --> 01:13:42,360
HELP RESEARCHERS THINK ABOUT

1703
01:13:42,360 --> 01:13:47,400
WHAT MIGHT MAKE SENSE FOR THEIR

1704
01:13:47,400 --> 01:13:48,040
PROJECTS.

1705
01:13:48,040 --> 01:13:50,160
ANOTHER AREA WHERE OUR NIH

1706
01:13:50,160 --> 01:13:51,200
COLLEAGUES AND INSTITUTES AND

1707
01:13:51,200 --> 01:13:52,800
CENTERS HAVE BEEN PROVIDING

1708
01:13:52,800 --> 01:13:54,240
ADDITIONAL RESOURCES RELATES TO

1709
01:13:54,240 --> 01:13:55,400
WHERE TO SHARE DATA.

1710
01:13:55,400 --> 01:13:56,480
AGAIN THIS IS AN AREA THAT'S

1711
01:13:56,480 --> 01:13:59,480
GOING TO VARY DEPENDING ON YOUR

1712
01:13:59,480 --> 01:14:01,200
RESEARCH AND DATA THAT YOU

1713
01:14:01,200 --> 01:14:02,680
GENERATING X SO THE DATA

1714
01:14:02,680 --> 01:14:03,440
MANAGEMENT AND SHARING POLICY

1715
01:14:03,440 --> 01:14:05,840
DOES NOT PRESCRIBE THE USE OF

1716
01:14:05,840 --> 01:14:07,920
ANY TECH REPOSITORY OR EVEN

1717
01:14:07,920 --> 01:14:09,280
REPOSITORIES BUT IT DOES

1718
01:14:09,280 --> 01:14:11,480
STRONGLY ENCOURAGE THE USE OF A

1719
01:14:11,480 --> 01:14:12,560
ESTABLISHED REPOSITORY BECAUSE

1720
01:14:12,560 --> 01:14:14,120
IT IMPROVES THE FAIRNESS OF THE

1721
01:14:14,120 --> 01:14:16,720
DATA SO THE FINDABILITY,

1722
01:14:16,720 --> 01:14:18,840
ACCESSIBILITY, AND

1723
01:14:18,840 --> 01:14:20,160
INTEROPERABILITY AND

1724
01:14:20,160 --> 01:14:20,800
REUSABILITY.

1725
01:14:20,800 --> 01:14:22,360
RATHER THAN POINTING TO TECH

1726
01:14:22,360 --> 01:14:24,720
REPOSITORIES, NIH HAS PROVIDED

1727
01:14:24,720 --> 01:14:25,840
CHARACTERISTICS TO LOOK FOR TO

1728
01:14:25,840 --> 01:14:28,600
HELP IDENTIFY SUITABLE

1729
01:14:28,600 --> 01:14:30,120
REPOSITORY AND THERE ARE EFFORTS

1730
01:14:30,120 --> 01:14:31,520
UNDERWAY WHICH I WON'T GET INTO

1731
01:14:31,520 --> 01:14:33,240
THE DETAILS OF TODAY, BUT FOCUS

1732
01:14:33,240 --> 01:14:36,720
ON HELPING THE STRENGTH AND THE

1733
01:14:36,720 --> 01:14:38,360
REPOSITORY LANDSCAPE TO ENSURE

1734
01:14:38,360 --> 01:14:43,480
THEY ARE SUITABLE REPOSITORIES.

1735
01:14:43,480 --> 01:14:45,120
THIS IS AN AREA WITH FLEXIBILITY

1736
01:14:45,120 --> 01:14:46,720
AND THEY MAY THROUGH INFORMATION

1737
01:14:46,720 --> 01:14:50,800
AND SPECIFIC FUNDING

1738
01:14:50,800 --> 01:15:01,240
OPPORTUNITIES DESIGNATE TO

1739
01:15:22,120 --> 01:15:23,560
PROVIDE ADDITIONAL AND SPECIFIC

1740
01:15:23,560 --> 01:15:25,120
EXPECTATIONS RELATED TO DATA

1741
01:15:25,120 --> 01:15:27,440
SHARING AND NIMH IS A LEADER IN

1742
01:15:27,440 --> 01:15:29,160
THE SPACE AS WELL OFFERING DATA

1743
01:15:29,160 --> 01:15:30,200
SHARING INFORMATION OR THE NIH

1744
01:15:30,200 --> 01:15:32,400
NOT FUNDED COMMUNITY.

1745
01:15:32,400 --> 01:15:34,280
SOME EXAMPLES ARE USE OF

1746
01:15:34,280 --> 01:15:36,800
DESIGNATED REPOSITORIES SUCH AS

1747
01:15:36,800 --> 01:15:39,440
THE ARCHIVE AND USE OF COMMON

1748
01:15:39,440 --> 01:15:41,920
DATA ELEMENTS AND SPECIFIC DATA

1749
01:15:41,920 --> 01:15:43,560
SUBMISSION SCHEDULES.

1750
01:15:43,560 --> 01:15:45,040
AND THEY HAVE BEEN PROVIDING

1751
01:15:45,040 --> 01:15:46,880
RESOURCES INCLUDING SAMPLEDEL

1752
01:15:46,880 --> 01:15:49,160
EMS PLAN AS WELL AS A COST NOT

1753
01:15:49,160 --> 01:15:51,880
TOOL FOR THE DATA ARCHIVE AND

1754
01:15:51,880 --> 01:15:54,400
WE'VE BEEN VERY GRATEFUL FOR THE

1755
01:15:54,400 --> 01:15:55,840
LEADERSHIP AND SUBJECT MATTER

1756
01:15:55,840 --> 01:15:58,160
EXPERTISE AND DATA SHARING THEY

1757
01:15:58,160 --> 01:15:59,600
HAVE BEEN PRESENT IN NIH WIDE

1758
01:15:59,600 --> 01:16:01,560
GROUPS FOCUSED ON THE DATA

1759
01:16:01,560 --> 01:16:03,400
MANAGEMENT AND SHARING POLICY

1760
01:16:03,400 --> 01:16:04,800
IMPLEMENTATION AND RELATED

1761
01:16:04,800 --> 01:16:05,160
ACTIVITIES.

1762
01:16:05,160 --> 01:16:12,200
NEXT SLIDE, PLEASE.

1763
01:16:12,200 --> 01:16:13,360
THERE'S A SCREEN SHOT OF THE

1764
01:16:13,360 --> 01:16:16,320
DATA SHARING WEBSITE.

1765
01:16:16,320 --> 01:16:18,480
SO IN TERMS OF RESOURCES, I'M

1766
01:16:18,480 --> 01:16:20,000
GOING BACK TO CENTRAL NIH

1767
01:16:20,000 --> 01:16:21,400
INFORMATION AND WE WANTED TO

1768
01:16:21,400 --> 01:16:22,920
POINT OUT WHERE YOU CAN FIND

1769
01:16:22,920 --> 01:16:26,120
ADDITIONAL INFORMATION ON

1770
01:16:26,120 --> 01:16:26,600
SHARING.

1771
01:16:26,600 --> 01:16:28,720
BEV A SCIENTIFIC DATA SHARING

1772
01:16:28,720 --> 01:16:29,600
SITE.

1773
01:16:29,600 --> 01:16:31,800
AND THIS COVERS MULTIPLE SHARING

1774
01:16:31,800 --> 01:16:32,640
POLICIES INCLUDING THE DATA

1775
01:16:32,640 --> 01:16:38,120
MANAGEMENT SHARING POLICY AND

1776
01:16:38,120 --> 01:16:40,040
LINKS OUT TO MORE INFORMATION ON

1777
01:16:40,040 --> 01:16:41,760
NIH INSTITUTE AND CENTERS

1778
01:16:41,760 --> 01:16:44,720
SPECIFIC EXPECTATIONS AND THIS

1779
01:16:44,720 --> 01:16:46,360
IS UPDATED AS ADDITIONAL

1780
01:16:46,360 --> 01:16:48,640
RESOURCES BECOME AVAILABLE SO IT

1781
01:16:48,640 --> 01:16:52,600
WILL ALWAYS SERVE AS A CENTRAL

1782
01:16:52,600 --> 01:16:53,400
ACCESS POINT.

1783
01:16:53,400 --> 01:16:55,360
AND IN TERMS OF PROVIDING

1784
01:16:55,360 --> 01:16:56,560
RESOURCES ON PLANNING AND

1785
01:16:56,560 --> 01:16:58,400
BUDGETING WHEN IT IT COMES TO

1786
01:16:58,400 --> 01:16:59,720
THE DATA MANAGEMENT AND SHARING

1787
01:16:59,720 --> 01:17:02,320
POLICY THE WEBSITE COVERS

1788
01:17:02,320 --> 01:17:04,600
INFORMATION TO INCLUDE WRITING A

1789
01:17:04,600 --> 01:17:05,240
PLAN AS WELL AS INFORMATION

1790
01:17:05,240 --> 01:17:07,360
ABOUT WHAT TYPES OF COSTS MAY BE

1791
01:17:07,360 --> 01:17:09,160
REQUESTED WHEN BUDGETING FOR THE

1792
01:17:09,160 --> 01:17:10,640
ACTIVITIES DESCRIBED IN YOUR

1793
01:17:10,640 --> 01:17:11,000
PLAN.

1794
01:17:11,000 --> 01:17:14,360
NEXT SLIDE, PLEASE.

1795
01:17:14,360 --> 01:17:15,880
SO DURING OUR OUTREACH

1796
01:17:15,880 --> 01:17:16,960
PRESENTATIONS, WE LIKE TO SEND

1797
01:17:16,960 --> 01:17:18,960
PEOPLE OFF WITH SOME CONCRETE

1798
01:17:18,960 --> 01:17:19,840
STEPS THEY CAN TAKE FOR

1799
01:17:19,840 --> 01:17:22,040
PREPARING FOR THE DMS POLICY AND

1800
01:17:22,040 --> 01:17:23,640
PERHAPS YOU OR YOUR COLLEAGUES

1801
01:17:23,640 --> 01:17:25,640
HAVE DONE SOME OF THESE.

1802
01:17:25,640 --> 01:17:26,920
SO, ONE THING IN ADDITION TO THE

1803
01:17:26,920 --> 01:17:28,880
NIH PROVIDED RESEARCHES WHICH

1804
01:17:28,880 --> 01:17:30,160
WE'RE COVERING TODAY, A NUMBER

1805
01:17:30,160 --> 01:17:31,920
OF INSTITUTIONS MIGHT HAVE

1806
01:17:31,920 --> 01:17:33,640
EXISTING RESOURCES AND COULD BE

1807
01:17:33,640 --> 01:17:35,680
VERY HELPFUL WHEN YOU ARE

1808
01:17:35,680 --> 01:17:37,160
CONSIDERING THE BEST WAY TO

1809
01:17:37,160 --> 01:17:38,560
MANAGE AND SHARE YOUR DATA AND

1810
01:17:38,560 --> 01:17:40,760
PARTICULAR DATA LIBRARIANS ARE

1811
01:17:40,760 --> 01:17:42,200
AN EXCELLENT RESEARCH THAT THEY

1812
01:17:42,200 --> 01:17:45,600
ARE AVAILABLE TO YOU.

1813
01:17:45,600 --> 01:17:48,360
AND HE ENCOURAGE TO LOOK AT THE

1814
01:17:48,360 --> 01:17:50,400
RELEVANT SAMPLE PLANS NOT SO THE

1815
01:17:50,400 --> 01:17:52,360
PLANS ARE AN EXCELLENT RESEARCH

1816
01:17:52,360 --> 01:17:54,640
THAT YOU HAVE AVAILABLE TO SEE

1817
01:17:54,640 --> 01:17:58,880
HOW THESE PLANS MIGHT BE

1818
01:17:58,880 --> 01:17:59,680
DESCRIBED.

1819
01:17:59,680 --> 01:18:01,240
TO DRY DRAFTING THE PLAN

1820
01:18:01,240 --> 01:18:02,640
YOURSELF EVEN IF YOU DON'T NEED

1821
01:18:02,640 --> 01:18:03,280
ONE YET.

1822
01:18:03,280 --> 01:18:05,800
JUST A GOOD IDEA TO KIND OF GET

1823
01:18:05,800 --> 01:18:07,760
SOME PRACTICE TO SEE WHETHER YOU

1824
01:18:07,760 --> 01:18:10,240
ARE PRACTICES, YOUR DATA SHARING

1825
01:18:10,240 --> 01:18:11,080
PRACTICES MIGHT NEED TO CHANGE

1826
01:18:11,080 --> 01:18:14,440
AT ALL.

1827
01:18:14,440 --> 01:18:16,280
YOU'VE BEEN SUBJECT TO OTHER

1828
01:18:16,280 --> 01:18:17,680
POLICIES AND GUIDELINES COMING

1829
01:18:17,680 --> 01:18:20,080
FROM FUNDERS AND TAKE A LOOK AT

1830
01:18:20,080 --> 01:18:21,480
WHAT YOU'VE BEEN DOING AND SEE

1831
01:18:21,480 --> 01:18:22,840
WHETHER ANY CHANGES ARE NEEDED

1832
01:18:22,840 --> 01:18:24,840
WITH THIS NEW NIH POLICY.

1833
01:18:24,840 --> 01:18:30,360
AND THEN FINALLY, WHEN YOU ARE

1834
01:18:30,360 --> 01:18:31,240
APPLYING WE ENCOURAGE YOU TO

1835
01:18:31,240 --> 01:18:32,720
READ THAT CAREFULLY BECAUSE

1836
01:18:32,720 --> 01:18:33,880
THERE MIGHT BE ADDITIONAL

1837
01:18:33,880 --> 01:18:34,840
PROGRAMS SPECIFIC NOT DATA

1838
01:18:34,840 --> 01:18:36,000
SHARING REQUIREMENTS FOR

1839
01:18:36,000 --> 01:18:37,080
INSTRUCTIONS THAT YOU NEED TO

1840
01:18:37,080 --> 01:18:44,600
TAKE INTO ACCOUNT.

1841
01:18:44,600 --> 01:18:45,800
NEXT STEMS FOR US WE ARE

1842
01:18:45,800 --> 01:18:47,920
PLANNING ON EVALUATION OF THE

1843
01:18:47,920 --> 01:18:49,280
DMS POLICY AND AGAIN WE ARE

1844
01:18:49,280 --> 01:18:50,240
REALLY IN LEARNING MODE HERE AND

1845
01:18:50,240 --> 01:18:51,200
IT'S A PRIORITY FOR US TO

1846
01:18:51,200 --> 01:18:54,160
UNDERSTAND NOT ONLY THE IMPACT

1847
01:18:54,160 --> 01:18:55,200
OF POLICY AND ALSO

1848
01:18:55,200 --> 01:18:59,000
IMPLEMENTATIONS WHAT IS WORKING

1849
01:18:59,000 --> 01:19:00,360
ADDITIONAL INFORMATION MIGHT BE

1850
01:19:00,360 --> 01:19:01,240
NEEDED.

1851
01:19:01,240 --> 01:19:03,040
AND SO NIH LEADERSHIP HAS

1852
01:19:03,040 --> 01:19:04,800
DESCRIBED PREVIOUSLY IN VARIOUS

1853
01:19:04,800 --> 01:19:09,480
BLOGS AND PUBLICATIONS, IS THIS

1854
01:19:09,480 --> 01:19:11,440
AIMS TO BRING ABOUT A CULTURAL

1855
01:19:11,440 --> 01:19:13,040
NIST RESEARCH SO INTEGRATING

1856
01:19:13,040 --> 01:19:14,560
DATA SHARING AS A FUNDAMENTAL

1857
01:19:14,560 --> 01:19:16,160
PART OF THE CONFLICT OF SCIENCE

1858
01:19:16,160 --> 01:19:18,360
AT NIH WE HAVE ONE LARGE TO PLAY

1859
01:19:18,360 --> 01:19:20,760
HERE BUT BEYOND OUR NIH SPECIFIC

1860
01:19:20,760 --> 01:19:22,160
IMPLEMENTATION ACTIVITIES, THIS

1861
01:19:22,160 --> 01:19:23,360
REALLY IS GOING TO BE A

1862
01:19:23,360 --> 01:19:25,560
COLLABORATION ACROSS THE ENTIRE

1863
01:19:25,560 --> 01:19:27,040
RESEARCH ECOSYSTEM SO WE HAVE

1864
01:19:27,040 --> 01:19:28,760
BEEN PARTICIPATING IN

1865
01:19:28,760 --> 01:19:29,680
CONVERSATIONS OTHER RELEVANT

1866
01:19:29,680 --> 01:19:31,440
PARTIES AND PUBLISHERS AND

1867
01:19:31,440 --> 01:19:34,960
RESEARCHERS AND INSTITUTIONAL

1868
01:19:34,960 --> 01:19:36,040
OFFICIALS AND PROFESSIONAL

1869
01:19:36,040 --> 01:19:38,680
ORGANIZATIONS ON THE TOP OF

1870
01:19:38,680 --> 01:19:39,280
INCENTIVIZING DATA SHARING

1871
01:19:39,280 --> 01:19:41,640
ACROSS THIS BIOMEDICAL

1872
01:19:41,640 --> 01:19:41,960
ECOSYSTEM.

1873
01:19:41,960 --> 01:19:45,560
NEXT SLIDE, PLEASE.

1874
01:19:45,560 --> 01:19:47,320
FOR THE LAST SLIDE WE WANT TO

1875
01:19:47,320 --> 01:19:48,520
LEAVE YOU WITH WHERE YOU CAN GO

1876
01:19:48,520 --> 01:19:49,320
FOR MORE INFORMATION.

1877
01:19:49,320 --> 01:19:50,600
THE SHARING WEBSITE IS THE HOME

1878
01:19:50,600 --> 01:19:52,280
TO ALL OF OUR RESOURCES ON THE

1879
01:19:52,280 --> 01:19:53,560
DATA MANAGEMENT AND SHARING

1880
01:19:53,560 --> 01:19:56,280
POLICY AND WE HAVE A DEDICATED

1881
01:19:56,280 --> 01:19:57,160
E-MAIL BOX FOR ANY QUESTIONS

1882
01:19:57,160 --> 01:19:59,320
FROM THE COMMUNITY SHARING AT

1883
01:19:59,320 --> 01:20:02,720
NIH.GOV AS WELL AS A SEPARATE

1884
01:20:02,720 --> 01:20:04,760
E-MAIL BOX NOR BUDGET OR COSTING

1885
01:20:04,760 --> 01:20:07,840
QUESTIONS SPECIFICALLY.

1886
01:20:07,840 --> 01:20:09,120
WE HAVE TIME FROM QUESTIONS FOR

1887
01:20:09,120 --> 01:20:11,280
YOU SO THAT'S THE END OF OUR

1888
01:20:11,280 --> 01:20:12,280
PRESENTATION AND WE'RE HAPPY TO

1889
01:20:12,280 --> 01:20:15,880
TAKE QUESTIONS OR COMMENTS.

1890
01:20:15,880 --> 01:20:23,160
>>THANK YOU SO MUCH.

1891
01:20:23,160 --> 01:20:23,600
OKAY, MARGARITE A.

1892
01:20:23,600 --> 01:20:25,760
>>THANK YOU SO MUCH FOR
THIS

1893
01:20:25,760 --> 01:20:26,240
PRESENTATION.

1894
01:20:26,240 --> 01:20:28,240
THAT WAS A LOT OF REALLY GREAT

1895
01:20:28,240 --> 01:20:28,800
INFORMATION.

1896
01:20:28,800 --> 01:20:33,080
ONE QUESTION THAT I HAVE, ONE

1897
01:20:33,080 --> 01:20:37,360
THING I -- THOSE DOING

1898
01:20:37,360 --> 01:20:38,800
QUALITATIVE RESEARCHES, HOW DO

1899
01:20:38,800 --> 01:20:41,200
THEY MAKE THAT JUSTIFICATION FOR

1900
01:20:41,200 --> 01:20:42,600
LIMITING SHARING AS A DATA AND I

1901
01:20:42,600 --> 01:20:44,000
WONDER IF YOU COULD SHARE WHO

1902
01:20:44,000 --> 01:20:47,920
AND HOW ARE THOSE DECISIONS

1903
01:20:47,920 --> 01:20:50,960
MADE?

1904
01:20:50,960 --> 01:20:53,000
OF I MEAN, MAYBE I'LL JUST START

1905
01:20:53,000 --> 01:20:54,400
SO YOU HAVE A SPECIFIC QUESTION

1906
01:20:54,400 --> 01:21:04,920
ABOUT A CERTAIN TIME OF IS AND

1907
01:21:08,400 --> 01:21:10,240
IT ALLOWS THE RESEARCHERS AND

1908
01:21:10,240 --> 01:21:12,440
THOSE ARE PROPOSING THE

1909
01:21:12,440 --> 01:21:14,040
APPROACHES THAT MAKE SENSE FOR

1910
01:21:14,040 --> 01:21:16,040
THEIR DATA IT'S BALANCED WITH A

1911
01:21:16,040 --> 01:21:18,880
NUMBER OF FAQs AND ADDITIONAL

1912
01:21:18,880 --> 01:21:22,080
RESOURCES FOR TO HELP YOU MAKE

1913
01:21:22,080 --> 01:21:22,480
THOSE DECISIONS.

1914
01:21:22,480 --> 01:21:23,480
I DON'T KNOW IF YOU WANT TO

1915
01:21:23,480 --> 01:21:25,240
POINT OUT ANY SPECIFIC RESOURCES

1916
01:21:25,240 --> 01:21:26,840
ON THAT QUESTION.

1917
01:21:26,840 --> 01:21:29,680
IT MIGHT BE USEFUL.

1918
01:21:29,680 --> 01:21:31,680
>>SPECIFIC, JUST TO
CLARIFY IT

1919
01:21:31,680 --> 01:21:34,000
WAS INTERESTED IN WHO IS THE

1920
01:21:34,000 --> 01:21:35,400
PERSON WHO A PROVES?

1921
01:21:35,400 --> 01:21:37,840
WE CAN COME UP WITH A PLAN BUT

1922
01:21:37,840 --> 01:21:39,200
APPROVERS, HOW ARE THEY MAKING

1923
01:21:39,200 --> 01:21:40,600
THOSE DECISION AND WE WANT TO

1924
01:21:40,600 --> 01:21:43,160
COME UP WITH A PLAN THAT

1925
01:21:43,160 --> 01:21:44,080
ADDRESSING THE CONCERNS THAT THE

1926
01:21:44,080 --> 01:21:48,440
PEOPLE ARE APPROVING.

1927
01:21:48,440 --> 01:21:51,680
OF THE PROGRAM OFFICER NAMED ON

1928
01:21:51,680 --> 01:21:54,040
THE NO FOE WILL MAKE THAT

1929
01:21:54,040 --> 01:21:55,400
DECISION AND THERE'S CERTAINLY

1930
01:21:55,400 --> 01:21:56,560
OPPORTUNITIES FOR A VISION BOTH

1931
01:21:56,560 --> 01:22:03,280
DURING THE JUST IN TIME PROCESS

1932
01:22:03,280 --> 01:22:07,360
AND THE RESEARCH CHANGE DATA

1933
01:22:07,360 --> 01:22:08,360
MANAGEMENT AND SHARING PLANS CAN

1934
01:22:08,360 --> 01:22:10,360
CHANGE TOO AND I DID WANT TO

1935
01:22:10,360 --> 01:22:12,200
ACKNOWLEDGE WE HAVE RECEIVED THE

1936
01:22:12,200 --> 01:22:14,960
QUESTION OF QUALITATIVE DATA AND

1937
01:22:14,960 --> 01:22:16,680
IT'S CHALLENGING TO THINK ABOUT

1938
01:22:16,680 --> 01:22:18,240
HOW TO PROTECT PRIVACY AND

1939
01:22:18,240 --> 01:22:19,040
SHARING THAT DATA AND MAKING

1940
01:22:19,040 --> 01:22:21,120
THAT ACCESSIBLE SO WE REALIZE

1941
01:22:21,120 --> 01:22:21,960
IT'S A DIFFICULT BALANCE AND

1942
01:22:21,960 --> 01:22:23,240
THERE ARE DIFFERENT CHALLENGES

1943
01:22:23,240 --> 01:22:27,520
ACROSS DIFFERENT KINDS OF

1944
01:22:27,520 --> 01:22:28,480
SCIENTIFIC DATA.

1945
01:22:28,480 --> 01:22:29,400
>>HELLO.

1946
01:22:29,400 --> 01:22:31,280
>>HI, I HAVE A SIMILAR
QUESTION

1947
01:22:31,280 --> 01:22:32,720
ABOUT A DIFFERENT TYPE OF DATA.

1948
01:22:32,720 --> 01:22:34,720
FIRST OF ALL, THANK YOU FOR THE

1949
01:22:34,720 --> 01:22:35,280
INFORMATIVE PRESENTATION.

1950
01:22:35,280 --> 01:22:36,960
I THINK THE SAMPLE PLANS AND THE

1951
01:22:36,960 --> 01:22:41,640
NIH APPROVED REPOSITORIES ARE

1952
01:22:41,640 --> 01:22:42,240
GREAT.

1953
01:22:42,240 --> 01:22:42,880
RESOURCE.

1954
01:22:42,880 --> 01:22:44,760
I DIDN'T SEE HOW DO I MANAGE THE

1955
01:22:44,760 --> 01:22:46,640
DATA THAT WE'RE COLLECTING FROM

1956
01:22:46,640 --> 01:22:48,040
SMARTPHONES AND WEARABLE DEVICES

1957
01:22:48,040 --> 01:22:49,560
AND THAT CAN BE SHARED AT

1958
01:22:49,560 --> 01:22:50,960
DIFFERENT LEVELS OF GRANULARITY

1959
01:22:50,960 --> 01:22:52,760
AND I'M WONDERING IF THERE ARE

1960
01:22:52,760 --> 01:22:56,440
ANY STANDARDS OR EXPECTATIONS

1961
01:22:56,440 --> 01:23:00,280
FOR WHAT LEVEL OF DETAILED

1962
01:23:00,280 --> 01:23:10,720
GRANULARITY ONE OF THE AREAS

1963
01:23:19,840 --> 01:23:20,960
WE'RE HOPING TO LEARN ABOUT WHEN

1964
01:23:20,960 --> 01:23:22,200
WE'RE TOGETHER WITH THE

1965
01:23:22,200 --> 01:23:26,280
COMMUNITY IS BOTH FROM THIS DATA

1966
01:23:26,280 --> 01:23:36,520
WHICH CAN BE.

1967
01:23:49,560 --> 01:23:50,760
>>THANK YOU FOR THE

1968
01:23:50,760 --> 01:23:51,480
PRESENTATION, I'M STRUCK BY THE

1969
01:23:51,480 --> 01:23:52,840
FACT THAT ONE HAS TO BE THINKING

1970
01:23:52,840 --> 01:23:57,160
ABOUT THESE ISSUES WHEN YOU ARE

1971
01:23:57,160 --> 01:24:07,680
DEVELOPING YOUR SO IN TERMS OF

1972
01:24:39,440 --> 01:24:40,640
THE RESOURCES WE HAVE TO HELP

1973
01:24:40,640 --> 01:24:42,440
INVESTIGATORS THINKING ABOUT

1974
01:24:42,440 --> 01:24:43,960
THESE, NIH RECENTLY SHARED A

1975
01:24:43,960 --> 01:24:49,440
POINTS TO CONSIDER DOCUMENT FOR

1976
01:24:49,440 --> 01:25:00,000
DEVELOPING INFORMS CONSENT A LOT

1977
01:25:20,920 --> 01:25:22,760
OF DIFFERENT FACTORS IS THAT GO

1978
01:25:22,760 --> 01:25:24,320
INTO INFORMED CONSENT DOCUMENTS.

1979
01:25:24,320 --> 01:25:26,800
WE ALSO HAVE A NUMBER OF

1980
01:25:26,800 --> 01:25:28,160
SUPPLEMENTAL NOT MATERIALS THAT

1981
01:25:28,160 --> 01:25:29,440
GETS GENERAL BEST PRACTICES OF

1982
01:25:29,440 --> 01:25:30,960
THINKING ABOUT PROTECTING

1983
01:25:30,960 --> 01:25:33,000
PRIVACY ACROSS DIFFERENT KINDS

1984
01:25:33,000 --> 01:25:36,120
OF DATA TYPES AND HUMAN RESOURCE

1985
01:25:36,120 --> 01:25:37,840
AND ANOTHER DOCUMENT THAT

1986
01:25:37,840 --> 01:25:39,840
FOCUSES ON CONSIDERATIONS WHEN

1987
01:25:39,840 --> 01:25:42,840
ENGAGING WITH TRIBAL COMMUNITIES

1988
01:25:42,840 --> 01:25:45,000
AND RESEARCH SO THERE ARE GOOD

1989
01:25:45,000 --> 01:25:46,040
STARTING POINTS AND I THINK THIS

1990
01:25:46,040 --> 01:25:48,960
IS ANOTHER REALLY GOOD EXAMPLE

1991
01:25:48,960 --> 01:25:50,280
OF DIALOGUE OF THE CONVERSATIONS

1992
01:25:50,280 --> 01:25:51,920
AND HOPEFULLY THAT WILL HAPPEN

1993
01:25:51,920 --> 01:25:55,720
IN A COMMUNITY ACROSS DIFFERENT

1994
01:25:55,720 --> 01:25:57,320
SCIENTIFIC AREAS TO HELP SHARE

1995
01:25:57,320 --> 01:26:02,080
LANGUAGE AND APPROACHES.

1996
01:26:02,080 --> 01:26:04,120
>>MATT.

1997
01:26:04,120 --> 01:26:05,360
>>THANK YOU.

1998
01:26:05,360 --> 01:26:07,040
THANK YOU FOR PRESENTING THIS

1999
01:26:07,040 --> 01:26:09,280
AND AS ALWAYS IT'S HELPFUL TO

2000
01:26:09,280 --> 01:26:10,160
SEE THE TEMPLATES.

2001
01:26:10,160 --> 01:26:14,640
I WANTED TO PUT, SECOND ABOUT

2002
01:26:14,640 --> 01:26:15,960
SMARTPHONES AND MONITORING AND

2003
01:26:15,960 --> 01:26:17,440
PUTTING A POINT ON A PIECE OF

2004
01:26:17,440 --> 01:26:18,960
THIS I'VE HEARD FROM RESEARCHERS

2005
01:26:18,960 --> 01:26:22,520
IN THE SI SCIENTIFIC COMMUNITY

2006
01:26:22,520 --> 01:26:24,520
DOING WORK WHERE GPS IS

2007
01:26:24,520 --> 01:26:26,200
COLLECTED AND THERE'S PRIVACY

2008
01:26:26,200 --> 01:26:27,560
CONCERN BECAUSE YOU SEE WHERE

2009
01:26:27,560 --> 01:26:29,600
PEOPLE ARE SLEEPING EVERY NIGHT

2010
01:26:29,600 --> 01:26:33,720
AND THEY HALT PEOPLE ON CHILDREN

2011
01:26:33,720 --> 01:26:35,520
AND PEOPLE AND SUICIDAL BEHAVIOR

2012
01:26:35,520 --> 01:26:36,800
AND VIOLENCE AND MENTAL HEALTH

2013
01:26:36,800 --> 01:26:38,720
AND DISORDERS AND SO ON THERE'S

2014
01:26:38,720 --> 01:26:42,360
CONCERN ABOUT SHARING THE DATA

2015
01:26:42,360 --> 01:26:42,640
IN RAW FORM.

2016
01:26:42,640 --> 01:26:43,800
I THINK DIFFERENT THINGS FROM

2017
01:26:43,800 --> 01:26:46,720
NIH SAYING NO, MUCH SHARE

2018
01:26:46,720 --> 01:26:48,200
EVERYTHING RAW IN RAW FORM AND

2019
01:26:48,200 --> 01:26:49,480
RESEARCHERS SAYING I DON'T WANT

2020
01:26:49,480 --> 01:26:52,040
TO, I'M PROTECTING THE PRIVACY

2021
01:26:52,040 --> 01:26:54,080
OF AND THEY EXPECT WE WON'T

2022
01:26:54,080 --> 01:26:54,800
SHARE RAW DATA.

2023
01:26:54,800 --> 01:26:56,520
IS THIS TO BE A CASE BY CASE

2024
01:26:56,520 --> 01:26:59,040
DATA WITH A PROGRAM OFFICER OR

2025
01:26:59,040 --> 01:27:00,520
GUIDANCE COMING ABOUT IF THE

2026
01:27:00,520 --> 01:27:01,240
DATA IS CERTAIN TYPE.

2027
01:27:01,240 --> 01:27:04,200
FOR INSTANCE, THEY'RE

2028
01:27:04,200 --> 01:27:07,360
DEFINITIVELY IDENTIFIABLE THEN

2029
01:27:07,360 --> 01:27:10,320
THEY'LL BE REQUEST IN SUMMARY

2030
01:27:10,320 --> 01:27:11,000
FORM AND PEOPLE ARE THINKING

2031
01:27:11,000 --> 01:27:12,080
ABOUT IT AND THEY'RE CONCERNED

2032
01:27:12,080 --> 01:27:12,680
ABOUT IT.

2033
01:27:12,680 --> 01:27:15,400
SO ANY GUIDANCE IS VERY MUCH

2034
01:27:15,400 --> 01:27:17,000
APPRECIATIVE.

2035
01:27:17,000 --> 01:27:17,360
THANK YOU.

2036
01:27:17,360 --> 01:27:19,320
>>SO I CAN JUST START OFF
IN

2037
01:27:19,320 --> 01:27:20,760
TERMS OF WHETHER THERE'S A

2038
01:27:20,760 --> 01:27:23,240
REQUIREMENT TO SHARE ANY

2039
01:27:23,240 --> 01:27:24,040
GRANULARITY OF DATA.

2040
01:27:24,040 --> 01:27:25,800
THE POLICY DOES NOT DICTATE

2041
01:27:25,800 --> 01:27:26,480
THAT.

2042
01:27:26,480 --> 01:27:29,480
IT REALLY DOES ALLOW THAT TO BE

2043
01:27:29,480 --> 01:27:30,960
DETERMINED IN TERMS OF WHAT DATA

2044
01:27:30,960 --> 01:27:32,280
DO UNDERLYING RESULTS BECAUSE

2045
01:27:32,280 --> 01:27:34,720
IT'S REALLY THE FOCUS OF THIS

2046
01:27:34,720 --> 01:27:35,640
HERE AND FOR A PARTICULAR

2047
01:27:35,640 --> 01:27:38,160
PROJECT IT MIGHT BE THAT PERHAPS

2048
01:27:38,160 --> 01:27:40,920
THE MOST USEFUL OR SOME SUMMARY.

2049
01:27:40,920 --> 01:27:42,040
NOW OF COURSE THERE MIGHT BE

2050
01:27:42,040 --> 01:27:43,120
SPECIFIC FUNDING OPPORTUNITIES

2051
01:27:43,120 --> 01:27:45,720
AND THEY CAN INTRODUCE SPECIFIC

2052
01:27:45,720 --> 01:27:46,800
EXPECTATIONS THERE AND THEY

2053
01:27:46,800 --> 01:27:48,760
MIGHT LAYOUT SOMETHING LIKE THAT

2054
01:27:48,760 --> 01:27:50,800
BUT IN GENERAL, IT'S REALLY MORE

2055
01:27:50,800 --> 01:27:52,840
OF A CASE BY CASE FOR

2056
01:27:52,840 --> 01:27:54,680
DETERMINING WHAT ACTUALLY IS

2057
01:27:54,680 --> 01:27:55,640
MAXIMIZING APPROPRIATE DATA

2058
01:27:55,640 --> 01:27:57,120
SHARING BECAUSE THAT'S THE

2059
01:27:57,120 --> 01:27:58,280
EXPECTATIONS OF THE POLICY

2060
01:27:58,280 --> 01:27:58,880
INTRODUCES.

2061
01:27:58,880 --> 01:28:00,080
IT DOESN'T REQUIRE YOU SHARE ALL

2062
01:28:00,080 --> 01:28:01,680
DATA, IT'S NOT A DIRECT

2063
01:28:01,680 --> 01:28:02,640
REQUIREMENT FOR SHARING IT'S

2064
01:28:02,640 --> 01:28:04,360
REALLY DETERMINING WHAT IS

2065
01:28:04,360 --> 01:28:05,920
APPROPRIATE AND IN SOME CASES IT

2066
01:28:05,920 --> 01:28:07,840
MIGHT MEAN LIMITING SHARING OR

2067
01:28:07,840 --> 01:28:10,480
SHARING IN A PARTICULAR WAY.

2068
01:28:10,480 --> 01:28:12,360
I DON'T KNOW IF YOU HAVE JUST

2069
01:28:12,360 --> 01:28:13,880
THINKING OF THE GENOMIC DATA

2070
01:28:13,880 --> 01:28:15,280
SHARING POLICY, FOR EXAMPLE,

2071
01:28:15,280 --> 01:28:16,680
WHICH IS IN A PLACE FOR A NUMBER

2072
01:28:16,680 --> 01:28:19,200
OF YEARS THAT MIGHT BE SOME

2073
01:28:19,200 --> 01:28:20,680
RELEVANT LESSON LEARNED HERE IN

2074
01:28:20,680 --> 01:28:23,000
TERMS OF WAYS TO SHARE THE DATA

2075
01:28:23,000 --> 01:28:25,280
WHEN THERE ARE PRIVACY

2076
01:28:25,280 --> 01:28:25,800
CONSIDERATIONS.

2077
01:28:25,800 --> 01:28:29,480
>>SO, JUST TO ADD A
COUPLE OF

2078
01:28:29,480 --> 01:28:31,960
THINGS TO CINDY'S RESPONSE.

2079
01:28:31,960 --> 01:28:34,080
AND JUST INQUIRING THAT THE

2080
01:28:34,080 --> 01:28:37,760
POLICY EXPECTATIONS AND

2081
01:28:37,760 --> 01:28:40,960
REQUIREMENTS SO THE POLICY

2082
01:28:40,960 --> 01:28:42,240
EXISTS OF OTHER REGULATION

2083
01:28:42,240 --> 01:28:44,200
THAT'S HAVE PROTECTIONS FOR DATA

2084
01:28:44,200 --> 01:28:45,320
FOR RESEARCH DATA AND CLINICAL

2085
01:28:45,320 --> 01:28:45,960
DATA.

2086
01:28:45,960 --> 01:28:48,680
SO, YOU KNOW, THE POLICY DOES

2087
01:28:48,680 --> 01:28:51,960
NOT IN ANYWAY SUPERSEDE HIPPA OR

2088
01:28:51,960 --> 01:28:57,000
THE FDA PROTECTION REGULATIONS

2089
01:28:57,000 --> 01:28:59,040
AND STATE LAWS AS WELL SO I

2090
01:28:59,040 --> 01:29:01,120
THINK THAT THERE'S A LOT OF ROOM

2091
01:29:01,120 --> 01:29:03,280
FOR RESEARCHERS TO THINK VERY

2092
01:29:03,280 --> 01:29:05,240
CAREFULLY IN THE WAY THAT SIGNED

2093
01:29:05,240 --> 01:29:07,000
MENTION BESIDES WHAT ARE OUR

2094
01:29:07,000 --> 01:29:07,800
APPROPRIATE WAYS TO SHARE DATA

2095
01:29:07,800 --> 01:29:10,840
AND FORMATS TO SHARE DATA IN A

2096
01:29:10,840 --> 01:29:14,160
WAY THAT PROTECTS PARTICIPANTS,

2097
01:29:14,160 --> 01:29:15,080
ESPECIALLY PARTICIPANTS THAT ARE

2098
01:29:15,080 --> 01:29:17,280
MEMBERS OF PEDIATRIC COMMUNITIES

2099
01:29:17,280 --> 01:29:18,560
AND OTHER VULNERABLE GROUPS.

2100
01:29:18,560 --> 01:29:19,920
THE OTHER THING TO ADD AND THIS

2101
01:29:19,920 --> 01:29:24,480
IS MENTIONED IN SOME OF THE

2102
01:29:24,480 --> 01:29:25,440
CIVIL INFORMATION YOU REFERRED

2103
01:29:25,440 --> 01:29:29,600
TO THAT TALK ABOUT ROBUST

2104
01:29:29,600 --> 01:29:31,200
REPOSITORY CHARACTER IS I CAN,

2105
01:29:31,200 --> 01:29:33,320
MANY SUPPORT REPOSITORIES LIKE

2106
01:29:33,320 --> 01:29:34,680
THE GAP WHERE THEY GET IT

2107
01:29:34,680 --> 01:29:36,800
COVERED UNDER THE GDS POLICIES

2108
01:29:36,800 --> 01:29:39,320
HOUSED HAVE CERTIFICATES OF

2109
01:29:39,320 --> 01:29:40,720
CONFIDENTIAL TEE THAT APPLY TO

2110
01:29:40,720 --> 01:29:43,320
THEM SO THOSE CAN PROTECT DATA

2111
01:29:43,320 --> 01:29:45,520
FROM COMPELLED CLOSURES AND THAT

2112
01:29:45,520 --> 01:29:50,920
IS PARTICULARLY, WELL, IF THE

2113
01:29:50,920 --> 01:29:52,400
JUDGE, THERE'S A LOT NOT NOT

2114
01:29:52,400 --> 01:29:57,800
MORE THAN IS THE INTENT AND

2115
01:29:57,800 --> 01:29:58,520
OBVIOUSLY THESE THINGS ARE

2116
01:29:58,520 --> 01:30:00,800
NEGOTIATED OUT IN COURT BUT THE

2117
01:30:00,800 --> 01:30:04,000
INTENT IS TO HEROINEST THE

2118
01:30:04,000 --> 01:30:06,880
PROTECTION OF COCs FROM

2119
01:30:06,880 --> 01:30:08,920
DATASETS SO JUST ANOTHER TOOL

2120
01:30:08,920 --> 01:30:10,760
FOR INVESTIGATORS TO BE AWARE

2121
01:30:10,760 --> 01:30:11,800
OF.

2122
01:30:11,800 --> 01:30:14,880
BUT IN THE GENOMIC DATA SPACE,

2123
01:30:14,880 --> 01:30:16,600
CERTAINLY REPOSITORIES AGAIN

2124
01:30:16,600 --> 01:30:20,080
JUST USING DB GAP AS AN EXAMPLE

2125
01:30:20,080 --> 01:30:22,200
WILL DEIDENTIFY DATA WITH

2126
01:30:22,200 --> 01:30:24,040
QUALITY CHECKS WHEN DATA SECURE

2127
01:30:24,040 --> 01:30:27,560
TO MAKE SURE THAT THERE AREN'T

2128
01:30:27,560 --> 01:30:28,560
IDENTIFIERS THAT UNINTENTIONALLY

2129
01:30:28,560 --> 01:30:29,880
MAKE IT THROUGH SO I THINK IT'S

2130
01:30:29,880 --> 01:30:31,400
ALSO IMPORTANT TO BE THINKING

2131
01:30:31,400 --> 01:30:34,600
ABOUT WHEN CONSIDERING WHICH

2132
01:30:34,600 --> 01:30:36,960
REPOSITORY DEPOSIT INTO THAT

2133
01:30:36,960 --> 01:30:38,880
HAVE ACCESS CONTROLS AND

2134
01:30:38,880 --> 01:30:41,920
CREATION AND GIVEN THE KINDS OF

2135
01:30:41,920 --> 01:30:44,480
DATA THAT WILL BE DEPOSITED.

2136
01:30:44,480 --> 01:30:46,720
>>GREG, I SEE THAT YOU
ARE

2137
01:30:46,720 --> 01:30:47,000
LINE.

2138
01:30:47,000 --> 01:30:49,800
DO YOU WANT TO COMMENT ABOUT

2139
01:30:49,800 --> 01:30:50,080
POLICY?

2140
01:30:50,080 --> 01:30:52,360
>>YEAH, I JUST WANTED TO
JUMP

2141
01:30:52,360 --> 01:30:53,120
IN HERE BECAUSE MATT THE

2142
01:30:53,120 --> 01:30:54,800
QUESTION YOU RAISED IS ONE THAT

2143
01:30:54,800 --> 01:30:57,840
WE'VE BEEN THINKING ABOUT A LOT.

2144
01:30:57,840 --> 01:31:00,800
I CAN TELL YOU WHAT OUR CURRENT

2145
01:31:00,800 --> 01:31:03,240
PLAN IS IN THE NIMH DATA ARCHIVE

2146
01:31:03,240 --> 01:31:05,800
BUT I WANT TO ECHO WHAT CINDY

2147
01:31:05,800 --> 01:31:07,280
AND JULIA HAVE SAID THAT WE'RE

2148
01:31:07,280 --> 01:31:09,360
ALL LEARNING HERE, RIGHT.

2149
01:31:09,360 --> 01:31:10,600
SO, WHAT WE'RE PLANNING ON DOING

2150
01:31:10,600 --> 01:31:12,800
WITH THE DATA FROM PERSONAL

2151
01:31:12,800 --> 01:31:15,280
TRACKING DEVICES IS THAT ANY

2152
01:31:15,280 --> 01:31:17,920
DATA STREAM THAT ACTUALLY HAS

2153
01:31:17,920 --> 01:31:19,960
GEO-SPACIAL LOCATIONS WILL BE

2154
01:31:19,960 --> 01:31:22,080
SEPARATED FROM THE DERIVED DATA

2155
01:31:22,080 --> 01:31:24,600
FROM THE PERSONAL TRACKING

2156
01:31:24,600 --> 01:31:25,280
DEVICE.

2157
01:31:25,280 --> 01:31:28,760
WE WILL MAKE BOTH DATA STREAMS

2158
01:31:28,760 --> 01:31:31,280
AVAILABLE, BUT, IF YOU WANT

2159
01:31:31,280 --> 01:31:32,800
GEO-SPACIAL LOCATIONS DATA YOU

2160
01:31:32,800 --> 01:31:34,960
HAVE TO PROVIDE US WITH PROOF

2161
01:31:34,960 --> 01:31:37,120
THAT YOU ARE IRB HAS APPROVED

2162
01:31:37,120 --> 01:31:37,560
NOT.

2163
01:31:37,560 --> 01:31:42,200
YOU ACCESSING THAT DATA AND YOU

2164
01:31:42,200 --> 01:31:45,280
HAVE HAVE SHOWN THEM THAT UP

2165
01:31:45,280 --> 01:31:47,240
APPROPRIATE CONTROLS OVER THE

2166
01:31:47,240 --> 01:31:48,920
VERY SENSITIVE DATA.

2167
01:31:48,920 --> 01:31:50,440
SO, I THINK THERE ARE PROBABLY

2168
01:31:50,440 --> 01:31:55,680
WAYS TO SOLVE THE PROBLEM BUT I

2169
01:31:55,680 --> 01:31:57,240
THINK WE'LL LEARN A LOT OVER THE

2170
01:31:57,240 --> 01:32:00,160
NEXT 12 MONTHS OR SO.

2171
01:32:00,160 --> 01:32:02,240
>>SO THANK YOU FOR THAT

2172
01:32:02,240 --> 01:32:06,800
CLARIFICATION, CAN I ASK FOR

2173
01:32:06,800 --> 01:32:07,720
FURTHER CLARIFICATION.

2174
01:32:07,720 --> 01:32:11,480
WHEN WE GET IRB APPROVAL TO

2175
01:32:11,480 --> 01:32:14,600
COLLECT LONGITUDE DATA MAKING

2176
01:32:14,600 --> 01:32:15,600
PARTICIPANTS IDENTIFIABLE.

2177
01:32:15,600 --> 01:32:17,560
IT SOUNDS LIKE THERE'S AN NIH

2178
01:32:17,560 --> 01:32:18,360
EXPECTATION THAT THOSE DATA

2179
01:32:18,360 --> 01:32:20,760
WOULD THEN BE SHARED WITH NIH

2180
01:32:20,760 --> 01:32:23,240
AND NIH WOULD BE THE DETERMINED

2181
01:32:23,240 --> 01:32:25,800
WHO GETS ACCESS TO THE RAW DATA?

2182
01:32:25,800 --> 01:32:27,280
>>I DON'T THINK I WOULD
GO AS

2183
01:32:27,280 --> 01:32:29,680
FAR AS SAYING THERE'S AN NIH

2184
01:32:29,680 --> 01:32:30,640
EXPECTATION, I THINK THAT FOR

2185
01:32:30,640 --> 01:32:34,080
THE PURPOSES OF NIMH PROGRAM

2186
01:32:34,080 --> 01:32:35,080
STAFF, THAT'S NOT HOW WE'RE

2187
01:32:35,080 --> 01:32:39,440
HOW WE'RE GOING TOSTART OUT ANDE

2188
01:32:39,440 --> 01:32:42,960
THEM AS WE NEED TO BUT YEAH, I

2189
01:32:42,960 --> 01:32:45,720
MEAN, YOU KNOW, IT'S SO EASY TO

2190
01:32:45,720 --> 01:32:48,000
IMAGINE THAT THE GEO-SPACIAL

2191
01:32:48,000 --> 01:32:52,640
LOCATION DATA REAL HE'S COULD

2192
01:32:52,640 --> 01:32:54,920
PROVIDE BIOMARKERS FOR THE SORTS

2193
01:32:54,920 --> 01:32:57,440
OF, THE SORTS OF DISEASES THAT

2194
01:32:57,440 --> 01:32:59,680
WE'RE INTERESTED IN THAT WE FEEL

2195
01:32:59,680 --> 01:33:07,400
IT'S QUITE 23508ISH TO SO

2196
01:33:07,400 --> 01:33:09,400
FOOLISH TO NOT COLLECT THAT DATA

2197
01:33:09,400 --> 01:33:10,400
UNTIL WE KNOW MORE.

2198
01:33:10,400 --> 01:33:13,560
>>THE SCHIZOPHRENIA IS
THE

2199
01:33:13,560 --> 01:33:15,000
FIRST DATASET THAT HAS THIS

2200
01:33:15,000 --> 01:33:16,560
INFORMATION MADE AVAILABLE AND

2201
01:33:16,560 --> 01:33:19,880
THAT IS GOING TO GO PUBLIC

2202
01:33:19,880 --> 01:33:20,800
SHORTLY.

2203
01:33:20,800 --> 01:33:23,720
WE'RE TALKING IN A COUPLE OF

2204
01:33:23,720 --> 01:33:24,960
MONTHS, THE FIRST VERSION OF IT.

2205
01:33:24,960 --> 01:33:27,240
>>I WOULD ENCOURAGE US TO
THINK

2206
01:33:27,240 --> 01:33:28,400
CAREFULLY AT NIH ABOUT HOW

2207
01:33:28,400 --> 01:33:29,920
SENSITIVE THE DATA IS AND THE

2208
01:33:29,920 --> 01:33:31,640
POTENTIAL FOR THEM TO BE SHARED

2209
01:33:31,640 --> 01:33:34,600
AND ESPECIALLY VULNERABLE MINORS

2210
01:33:34,600 --> 01:33:35,040
IDENTIFIED.

2211
01:33:35,040 --> 01:33:36,160
>>THANK YOU FOR THOSE
COMMENTS,

2212
01:33:36,160 --> 01:33:36,840
MATT.

2213
01:33:36,840 --> 01:33:39,320
THOSE ARE HEAD.

2214
01:33:39,320 --> 01:33:49,920
NOT TED, YOU ARE NEXT AND I HAD

2215
01:33:54,560 --> 01:33:58,280
SOME KIND OF BROADER QUESTIONS

2216
01:33:58,280 --> 01:34:02,160
AND I'M KIND OF -- I SEE A LOT

2217
01:34:02,160 --> 01:34:03,320
OF THE CONVENTION BUT MINE IS

2218
01:34:03,320 --> 01:34:05,440
FROM THE PERSPECTIVE OF THE

2219
01:34:05,440 --> 01:34:07,240
SCIENTIFIC ENTERPRISE.

2220
01:34:07,240 --> 01:34:08,480
AND I'M A LITTLE WORRIED THAT

2221
01:34:08,480 --> 01:34:11,400
WE'RE GOING TO WIND UP IN A

2222
01:34:11,400 --> 01:34:13,120
SITUATION OF HAVING WATER AND

2223
01:34:13,120 --> 01:34:16,120
NOT A DROPPED DRINK WITH A WHOLE

2224
01:34:16,120 --> 01:34:18,200
BUNCH OF DATA THAT WE CAN'T MAKE

2225
01:34:18,200 --> 01:34:19,760
SENSE OF AND UNDERSTAND AND IN

2226
01:34:19,760 --> 01:34:23,960
ANY EXPERIENCE, IN UNDERSTANDING

2227
01:34:23,960 --> 01:34:30,000
COMPLEX SCIENTIFIC PAPERS AND

2228
01:34:30,000 --> 01:34:32,960
IT'S BEEN ACCESSED TO REAGENTS

2229
01:34:32,960 --> 01:34:43,480
AND METHODOLOGY, AND OF FIRSTLY,

2230
01:35:13,840 --> 01:35:18,280
SOME OF THAT DATA CAN'T BE

2231
01:35:18,280 --> 01:35:28,800
ARCHIVED AND FAIR ENOUGH AND WE

2232
01:35:32,360 --> 01:35:33,720
NEED TO FIGURE OUT HOW TO STORE

2233
01:35:33,720 --> 01:35:38,000
ALL OF THIS AND WHILE WE THINK

2234
01:35:38,000 --> 01:35:40,640
ABOUT STORING THIS, LET'S THINK

2235
01:35:40,640 --> 01:35:42,240
IF WE CAN USE IT AND I'M WORRIED

2236
01:35:42,240 --> 01:35:43,400
ABOUT THAT.

2237
01:35:43,400 --> 01:35:44,680
THAT'S MY GENERAL COMMENT WHICH

2238
01:35:44,680 --> 01:35:46,800
DOESN'T HELP IN IMPLEMENTING IT

2239
01:35:46,800 --> 01:35:49,120
BUT THERE MAY BE PILOT

2240
01:35:49,120 --> 01:35:50,480
INITIATIVES YOU CAN DO.

2241
01:35:50,480 --> 01:35:52,480
THERE'S CLEAR DATABASES AND

2242
01:35:52,480 --> 01:35:53,880
DATASETS THAT ARE -- I'M NOT A

2243
01:35:53,880 --> 01:36:00,600
DATA SIGN TIVE AND BUT THAT

2244
01:36:00,600 --> 01:36:02,320
THINKING ABOUT CELL PHONE DATA

2245
01:36:02,320 --> 01:36:06,720
AND BEHAVIORAL DATA FROM

2246
01:36:06,720 --> 01:36:11,800
SUBJECTS AND GOING TO A GAR

2247
01:36:11,800 --> 01:36:14,440
GRAPH AND NO ACTUAL DATA SO YOU

2248
01:36:14,440 --> 01:36:16,040
DO A DATA SHARING PLANT AND YOU

2249
01:36:16,040 --> 01:36:20,880
HAVE VIDEOS AVAILABLE AND THAT

2250
01:36:20,880 --> 01:36:26,120
IN A CASE OF EMERGING

2251
01:36:26,120 --> 01:36:26,760
TECHNOLOGIES, LIKE SPACIAL THAT

2252
01:36:26,760 --> 01:36:28,320
AREN'T EMERGING ANYMORE YOU HAVE

2253
01:36:28,320 --> 01:36:29,840
TO MERGE ALL OF THE IMAGING

2254
01:36:29,840 --> 01:36:30,640
DATABASE WHICH ARE HARD ENOUGH

2255
01:36:30,640 --> 01:36:32,560
TO GENERATE WITH ALL THE GENE

2256
01:36:32,560 --> 01:36:34,400
EXPRESSION DATABASE AND HARD

2257
01:36:34,400 --> 01:36:35,720
ENOUGH TO GENERATE AND PUT THEM

2258
01:36:35,720 --> 01:36:36,360
TOGETHER.

2259
01:36:36,360 --> 01:36:37,440
THERE ARE REAL SPECIFIC, WITHIN

2260
01:36:37,440 --> 01:36:40,680
THE NIMH AREAS OF TRACTION THAT

2261
01:36:40,680 --> 01:36:44,200
ONE CAN THINK ABOUT AND I'M SURE

2262
01:36:44,200 --> 01:36:45,840
MOW BROADLY ACROSS NIH IS THE

2263
01:36:45,840 --> 01:36:46,760
CASE AND THINKING ABOUT

2264
01:36:46,760 --> 01:36:53,280
INVESTMENTS OF THEM SO WE CAN

2265
01:36:53,280 --> 01:36:56,200
ACTUALLY NOT JUST FOR HEALTH BUT

2266
01:36:56,200 --> 01:36:56,680
FOR UNDERSTANDING.

2267
01:36:56,680 --> 01:37:07,160
SO THAT'S MY GENERAL COMMENT.

2268
01:37:35,880 --> 01:37:38,400
IS THINKING ABOUT A PUBLICATION

2269
01:37:38,400 --> 01:37:40,000
WOULD BE MAYBE NOT INVALUABLE

2270
01:37:40,000 --> 01:37:41,520
BECAUSE IT'S CHANGING AND THE

2271
01:37:41,520 --> 01:37:43,480
OTHER THING IN THIS SPACE THAT I

2272
01:37:43,480 --> 01:37:46,880
THINK I ACTUALLY REALLY LIKE IS

2273
01:37:46,880 --> 01:37:49,800
THE DISRUPTION THAT YOU HAVE AN

2274
01:37:49,800 --> 01:37:51,640
OPPORTUNITY TO CAUSE IN THE

2275
01:37:51,640 --> 01:37:52,760
SCIENTIFIC COMMUNITY AND THAT IS

2276
01:37:52,760 --> 01:37:55,240
THE DISRUPTION IN THINKING ABOUT

2277
01:37:55,240 --> 01:37:58,920
THE WORTH OF A SCIENTIST BEYOND

2278
01:37:58,920 --> 01:38:02,760
HIS OR HER H INDEX EYESIGHT

2279
01:38:02,760 --> 01:38:05,160
NUMBER AND AS WE HAVE DATASETS

2280
01:38:05,160 --> 01:38:07,000
AND THINGS WE HAVE TO FIGURE OUT

2281
01:38:07,000 --> 01:38:08,520
HOW WE ACKNOWLEDGE THE

2282
01:38:08,520 --> 01:38:09,480
CONTRIBUTIONS OF INDIVIDUALS TO

2283
01:38:09,480 --> 01:38:11,080
ALL OF THIS ENTERPRISE AND

2284
01:38:11,080 --> 01:38:12,760
THAT'S JUST A COMMENT TO SPACE

2285
01:38:12,760 --> 01:38:14,760
AS MANY OF MINE HAVE BEEN BUT

2286
01:38:14,760 --> 01:38:16,600
THEY'RE IN IMPORTANT

2287
01:38:16,600 --> 01:38:18,360
IMPLICATIONS OF THIS AND WHAT IS

2288
01:38:18,360 --> 01:38:19,600
TERRIFIC ABOUT ALL OF THIS I

2289
01:38:19,600 --> 01:38:21,600
THINK YOU ALL, IT'S GREAT TO SEE

2290
01:38:21,600 --> 01:38:25,720
THE THINGS EVOLVE.

2291
01:38:25,720 --> 01:38:28,160
IS THE THOUGHT TO EVOLVE THIS SO

2292
01:38:28,160 --> 01:38:32,720
THAT THE REVIEW MIGHT EVENTUALLY

2293
01:38:32,720 --> 01:38:34,480
BE, THE REVIEW MIGHT BE IN THE

2294
01:38:34,480 --> 01:38:35,560
HANDS OF THE VIEWERS OR IS IT

2295
01:38:35,560 --> 01:38:39,680
THOUGHT IT WILL STAY WITH THE

2296
01:38:39,680 --> 01:38:39,920
PROGRAM.

2297
01:38:39,920 --> 01:38:42,080
>>RIGHT NOW THAT DECISION
THERE

2298
01:38:42,080 --> 01:38:43,480
WAS A LOT OF CONSIDERATION

2299
01:38:43,480 --> 01:38:45,400
DURING THE POLICY DEVELOPMENT

2300
01:38:45,400 --> 01:38:47,600
PHASE AND AS IT STANDS ON THE

2301
01:38:47,600 --> 01:38:48,880
FINAL POLICY THE DECISION WAS

2302
01:38:48,880 --> 01:38:50,000
MADE THAT THE PROGRAM STAFF

2303
01:38:50,000 --> 01:38:52,680
WOULD BE REVIEWED NOT AND PEER

2304
01:38:52,680 --> 01:38:54,200
REVIEWERS SO AS OF NOW, THERE'S

2305
01:38:54,200 --> 01:39:04,640
NO PLANS TO CHANGE THAT AND.

2306
01:39:13,280 --> 01:39:14,320
>>THANK YOU, THAT WAS A
LOT OF

2307
01:39:14,320 --> 01:39:16,320
INFORMATION AND I APPRECIATE ALL

2308
01:39:16,320 --> 01:39:17,440
THE COMMENTS COMING FROM MY

2309
01:39:17,440 --> 01:39:18,160
COLLEAGUES.

2310
01:39:18,160 --> 01:39:20,120
I'M GOING TO ACTUALLY SHIFT TO A

2311
01:39:20,120 --> 01:39:22,920
VERY SIMPLE PRACTICAL TYPE OF

2312
01:39:22,920 --> 01:39:23,960
THING.

2313
01:39:23,960 --> 01:39:27,080
ONE OF THE CONCERNS THAT HAS

2314
01:39:27,080 --> 01:39:32,760
REALLY GROWN UP IS OUR ABILITY

2315
01:39:32,760 --> 01:39:37,840
TO ENGAGE, TRAIN, WORK WITH

2316
01:39:37,840 --> 01:39:39,400
PERSONS WHO ARE NEARLY NEW TO

2317
01:39:39,400 --> 01:39:41,120
THE WHOLE PROCESS ITSELF.

2318
01:39:41,120 --> 01:39:42,480
SO, YOU MAY HAVE MENTIONED IT

2319
01:39:42,480 --> 01:39:53,000
AND I APOLOGIZE THE POLL SEC,

2320
01:39:55,520 --> 01:39:56,600
METHODOLOGY AND THE ELEMENTS OF

2321
01:39:56,600 --> 01:40:02,360
THAT AND THEN THE ACTUAL PERSONS

2322
01:40:02,360 --> 01:40:05,360
THEMSELVES ARE THEY WORK WITH

2323
01:40:05,360 --> 01:40:06,840
PRE DOCUMENTS AND POSTDOCS AND

2324
01:40:06,840 --> 01:40:08,640
WHO ARE JUST BEGINNING AND

2325
01:40:08,640 --> 01:40:19,200
WALKING INTO THIS AND THEY HAVE

2326
01:40:20,200 --> 01:40:23,120
BACKGROUND OR NO BACKGROUND SO

2327
01:40:23,120 --> 01:40:24,520
IT'S IMPORTANT BECAUSE IT'S

2328
01:40:24,520 --> 01:40:27,120
IMPORTANT FOR US TO CONSIDER THE

2329
01:40:27,120 --> 01:40:29,160
LONG-TERM PART OF THIS IS THAT A

2330
01:40:29,160 --> 01:40:30,360
LOT OF US, A LOT OF PEOPLE HAVE

2331
01:40:30,360 --> 01:40:33,400
A GOOD UNDERSTANDING OF THIS

2332
01:40:33,400 --> 01:40:34,200
BECAUSE THEY HAVE BEEN DOING IT

2333
01:40:34,200 --> 01:40:35,760
FOR A WHILE BUT THERE'S A LOT OF

2334
01:40:35,760 --> 01:40:37,400
PEOPLE COMING IN WHO DO NOT AND

2335
01:40:37,400 --> 01:40:39,000
I'M MORE CONCERNED ABOUT THEM

2336
01:40:39,000 --> 01:40:40,160
COMING IN BECAUSE WE GIVE THEM

2337
01:40:40,160 --> 01:40:43,960
OUR RESPONSIBILITY AND THEY DO

2338
01:40:43,960 --> 01:40:54,040
NOT.

2339
01:41:11,360 --> 01:41:13,680
THEY CLAIRELY HAVE THEIR OWN

2340
01:41:13,680 --> 01:41:15,640
CHALLENGE, THEIR OWN SPECIFICS

2341
01:41:15,640 --> 01:41:17,400
IN TERMS OF WHAT THEY ALLOW AND

2342
01:41:17,400 --> 01:41:18,560
WHAT THEY WON'T ALLOW IN TERMS

2343
01:41:18,560 --> 01:41:22,520
OF DATA SHARING AND THAT SORT OF

2344
01:41:22,520 --> 01:41:27,240
THING.

2345
01:41:27,240 --> 01:41:29,560
WE TRAIN TO RESPOND TO RISK

2346
01:41:29,560 --> 01:41:30,720
AVERSE TYPES OF PERSON AS WELL.

2347
01:41:30,720 --> 01:41:32,240
IT ALL INVOLVES AROUND TRAINING

2348
01:41:32,240 --> 01:41:33,960
IN TERMS OF METHOD AND IN TERMS

2349
01:41:33,960 --> 01:41:36,760
OF STRATEGY AND THAT IS REALLY

2350
01:41:36,760 --> 01:41:37,760
IMPORTANT BECAUSE IN THE LONG

2351
01:41:37,760 --> 01:41:39,520
RUN IT IS WHAT GOES TO TODAY TO

2352
01:41:39,520 --> 01:41:40,360
ANSWER TO Y'ALL.

2353
01:41:40,360 --> 01:41:44,200
I HOPE THAT WASN'T TOO

2354
01:41:44,200 --> 01:41:48,080
COMPLICATED OR TOO -- TO

2355
01:41:48,080 --> 01:41:49,640
CONGREGATED TYPE OF QUESTIONS

2356
01:41:49,640 --> 01:41:51,160
BUT I THOUGHT ABOUT IT LISTENING

2357
01:41:51,160 --> 01:41:52,720
TO EVERYTHING THAT IS GOING ON

2358
01:41:52,720 --> 01:41:55,480
BUT THANK YOU FOR THIS.

2359
01:41:55,480 --> 01:41:57,080
>>SO A LOT OF GOOD POINTS
THERE

2360
01:41:57,080 --> 01:41:57,680
AND QUESTIONS.

2361
01:41:57,680 --> 01:42:00,120
IN TERMS OF TRAINING, SO,

2362
01:42:00,120 --> 01:42:02,080
THERE'S TRAINING ON WHAT THE NIH

2363
01:42:02,080 --> 01:42:03,640
POLICY REQUIRES AND EXPECTS AND

2364
01:42:03,640 --> 01:42:05,960
WE HAVE A LOT OF RESOURCES ON

2365
01:42:05,960 --> 01:42:06,600
THAT IN PARTICULAR.

2366
01:42:06,600 --> 01:42:09,120
I WOULD ENCOURAGE YOU OR ANY NOT

2367
01:42:09,120 --> 01:42:10,400
TRAINEES OR POSTDOCS WHO ARE

2368
01:42:10,400 --> 01:42:11,560
INTERESTED AND THEY CAN GO BACK

2369
01:42:11,560 --> 01:42:14,120
AND LOOK AT THE TWO-PART WEBINAR

2370
01:42:14,120 --> 01:42:18,000
AND IN THE SUM YOUR WORSHIP OF

2371
01:42:18,000 --> 01:42:19,600
2022 AND THEY WERE EACH 90

2372
01:42:19,600 --> 01:42:21,680
MINUTES AND COVERING ALL THE

2373
01:42:21,680 --> 01:42:22,480
AVAILABLE RESOURCES WE HAD AND

2374
01:42:22,480 --> 01:42:23,560
COMMON QUESTIONS ABOUT THE

2375
01:42:23,560 --> 01:42:24,640
POLICY IN TERMS OF GETTING

2376
01:42:24,640 --> 01:42:26,040
FAMILIAR WITH WHAT IS NEEDED AND

2377
01:42:26,040 --> 01:42:27,640
HOW THAT MIGHT CHANGE THEIR

2378
01:42:27,640 --> 01:42:30,720
PRACTICES, AND ONE AREA TO POINT

2379
01:42:30,720 --> 01:42:31,720
FOLKS TO.

2380
01:42:31,720 --> 01:42:32,440
BEYOND THAT I REMEMBER ALSO

2381
01:42:32,440 --> 01:42:36,720
GETTING INTO THE QUESTIONS AND

2382
01:42:36,720 --> 01:42:40,040
TRAINING AND RESEARCH BASED ON

2383
01:42:40,040 --> 01:42:42,160
WHAT YOUR INSTITUTION MIGHT

2384
01:42:42,160 --> 01:42:43,240
REQUIRE AND YOUR INDEPENDENT

2385
01:42:43,240 --> 01:42:44,440
AREA OF SCIENCE AND IT'S GOING

2386
01:42:44,440 --> 01:42:54,920
TO VARY SO ONE THING TO MOVE

2387
01:43:25,720 --> 01:43:26,920
SCIENCE FORWARD AND WE HAVE

2388
01:43:26,920 --> 01:43:28,520
COLLEAGUES AND NIH OFFICE OF

2389
01:43:28,520 --> 01:43:31,640
DATA SHARING STRATEGIES OR ODSS

2390
01:43:31,640 --> 01:43:33,240
AND I'M NOT PUTTING ANYTHING

2391
01:43:33,240 --> 01:43:35,000
SPECIFIC HERE BUT JUST MENTIONED

2392
01:43:35,000 --> 01:43:38,440
THEY HAVE AN INTEREST IN LOOKING

2393
01:43:38,440 --> 01:43:41,640
AT HOW DATA CAN BE REUSED AND IN

2394
01:43:41,640 --> 01:43:42,800
PARTICULAR THE HIGHLIGHTED SOME

2395
01:43:42,800 --> 01:43:45,560
EXAMPLES OF HOW RESEARCHERS HAVE

2396
01:43:45,560 --> 01:43:47,160
DONE SOME ARE DATASETS AND

2397
01:43:47,160 --> 01:43:48,760
DEVELOPED SOME NEW KNOWLEDGE

2398
01:43:48,760 --> 01:43:50,480
FROM THAT SO WE MAY BE SEEING

2399
01:43:50,480 --> 01:43:53,840
SOME PRACTICAL EXAMPLES OF THAT

2400
01:43:53,840 --> 01:43:54,560
MIGHT HELP.

2401
01:43:54,560 --> 01:43:58,480
ANY OTHER THOUGHTS ON THAT ONE?

2402
01:43:58,480 --> 01:44:00,680
>>ANY RESOURCES THAT WE
CAN

2403
01:44:00,680 --> 01:44:00,920
ADD.

2404
01:44:00,920 --> 01:44:04,440
I DO THINK THAT THERE'S FORMS

2405
01:44:04,440 --> 01:44:07,280
AND WE KNOW THAT PROJECT PILOT

2406
01:44:07,280 --> 01:44:11,960
BUT THAT'S ONE MENU WHERE

2407
01:44:11,960 --> 01:44:12,800
ADMINISTRATORS CAN COME TOGETHER

2408
01:44:12,800 --> 01:44:15,200
AND HAVE CONVERSATIONS JUST

2409
01:44:15,200 --> 01:44:16,120
ABOUT BEST PRACTICES AND OTHER

2410
01:44:16,120 --> 01:44:17,320
INSTITUTIONS SO I THINK THAT

2411
01:44:17,320 --> 01:44:19,160
HOPEFULLY THEY'LL BE INCREASING

2412
01:44:19,160 --> 01:44:20,520
FORMS FOR GENERAL COUNCIL

2413
01:44:20,520 --> 01:44:24,360
OFFICES AND OTHER KINDS OF NOT

2414
01:44:24,360 --> 01:44:26,000
RULES IN THE ENTERPRISE TO HAVE

2415
01:44:26,000 --> 01:44:27,680
CONVERSATIONS ABOUT DATA

2416
01:44:27,680 --> 01:44:28,000
SHARING.

2417
01:44:28,000 --> 01:44:30,560
>>I'M SORRY, DID YOU SAY
FORUMS

2418
01:44:30,560 --> 01:44:30,960
OR FORMS?

2419
01:44:30,960 --> 01:44:33,400
I'M SORRY.

2420
01:44:33,400 --> 01:44:33,560
NOT.

2421
01:44:33,560 --> 01:44:35,800
>>I'M THINKING ABOUT
FORUMS AND

2422
01:44:35,800 --> 01:44:38,640
OPPORTUNITIES FOR THOSE ROLES TO

2423
01:44:38,640 --> 01:44:39,120
COME TOGETHER.

2424
01:44:39,120 --> 01:44:42,720
>>LAURA --

2425
01:44:42,720 --> 01:44:44,440
>>HI, THANK YOU VERY
MUCH.

2426
01:44:44,440 --> 01:44:45,840
I MISSED THE FIRST PART OF THE

2427
01:44:45,840 --> 01:44:47,320
PRESENTATION SO THIS MAY BE

2428
01:44:47,320 --> 01:44:49,080
REPETITIVE SO JUST LET ME KNOW.

2429
01:44:49,080 --> 01:44:51,680
I'M CURIOUS ABOUT THIS AS

2430
01:44:51,680 --> 01:44:52,960
SOMEONE WHO HAS HAD PEOPLE IN

2431
01:44:52,960 --> 01:44:56,560
THEIR GROUP WRESTLE FOR DB GAPS

2432
01:44:56,560 --> 01:44:58,040
SOMETIMES FOR YEARS.

2433
01:44:58,040 --> 01:45:00,520
TO GET DATA IN.

2434
01:45:00,520 --> 01:45:03,280
IF THERE ARE BENCHMARKS, THAT

2435
01:45:03,280 --> 01:45:07,000
ARE GOING TO BE PUT IN PLACE FOR

2436
01:45:07,000 --> 01:45:09,840
THE GOVERNMENTAL DATASETS, THAT

2437
01:45:09,840 --> 01:45:12,200
WOULD SAY YOU KNOW, THE

2438
01:45:12,200 --> 01:45:13,680
EXPECTATION IS THAT PEOPLE WILL

2439
01:45:13,680 --> 01:45:19,720
BE GOTTEN BACK TO IN X AMOUNT OF

2440
01:45:19,720 --> 01:45:22,160
DAYS AND THAT THINGS WILL BE

2441
01:45:22,160 --> 01:45:23,520
ESCALATED TO SOLVE PROBLEMS SO

2442
01:45:23,520 --> 01:45:26,600
THAT ON AVERAGE, WHEN SOMEONE

2443
01:45:26,600 --> 01:45:28,880
STARTS TO SUBMIT THEIR DATA,

2444
01:45:28,880 --> 01:45:31,400
DATA WILL BE IN WITHIN A MONTH,

2445
01:45:31,400 --> 01:45:34,280
WITHIN TWO MONTHS AND WHAT

2446
01:45:34,280 --> 01:45:36,640
METRICS AND I GUESS ALSO WHAT

2447
01:45:36,640 --> 01:45:38,600
RESOURCES EACH DATABASE IS

2448
01:45:38,600 --> 01:45:40,360
PLANNING TO PUT IN PLACE SO THAT

2449
01:45:40,360 --> 01:45:43,000
THIS REALLY WORKS SO THAT DATA

2450
01:45:43,000 --> 01:45:52,400
IS IN A TIMELY WAY DEPOSITED.

2451
01:45:52,400 --> 01:45:53,720
>>I REALLY APPRECIATE
THAT

2452
01:45:53,720 --> 01:45:54,280
QUESTION.

2453
01:45:54,280 --> 01:45:55,160
IT'S NOT THE FIRST TIME THAT

2454
01:45:55,160 --> 01:45:59,840
WE'VE HEARD THAT DB GAP CAN BE

2455
01:45:59,840 --> 01:46:01,680
CHALLENGING TO THE DATA IN AND

2456
01:46:01,680 --> 01:46:03,600
TO GET DATA OUT.

2457
01:46:03,600 --> 01:46:05,600
I WORK CLOSELY WITH OUR

2458
01:46:05,600 --> 01:46:06,600
COLLEAGUES -- I WILL SAY OVER

2459
01:46:06,600 --> 01:46:09,400
THE LAST COUPLE OF YEARS, NC BYE

2460
01:46:09,400 --> 01:46:11,000
HAS DEVOTED A LOT OF THINKING

2461
01:46:11,000 --> 01:46:13,000
AND RESOURCES TO WORKFLOWS AND

2462
01:46:13,000 --> 01:46:14,920
SUPPORTING AND ENHANCING DATA

2463
01:46:14,920 --> 01:46:17,240
STAFF TO MAKE THAT PROCESSES

2464
01:46:17,240 --> 01:46:19,880
YEAR FOR DATA SUBMITTERS AND ON

2465
01:46:19,880 --> 01:46:22,240
THE OTHER SIDE DATA ACCESSERS.

2466
01:46:22,240 --> 01:46:25,880
AND THERE ARE SOME METRICS WE

2467
01:46:25,880 --> 01:46:26,800
HAVE USABILITY OF REQUESTS AND

2468
01:46:26,800 --> 01:46:29,400
THE ACCESS SIDE.

2469
01:46:29,400 --> 01:46:32,280
THAT GO INTO DB GAP TO BE

2470
01:46:32,280 --> 01:46:36,560
TRANSPARENT ABOUT THE VOLUME OF

2471
01:46:36,560 --> 01:46:38,840
OF REQUESTS THAT WE RECEIVED AND

2472
01:46:38,840 --> 01:46:40,680
THE VOLUME HAS GONE UP

2473
01:46:40,680 --> 01:46:44,760
SIGNIFICANTLY OVER THE PAST FIVE

2474
01:46:44,760 --> 01:46:46,280
TO SEVEN YEARS.

2475
01:46:46,280 --> 01:46:50,040
JURY POINT IS TAKEN ABOUT BEING

2476
01:46:50,040 --> 01:46:51,760
AWARE OF REPOSITORIES NOT

2477
01:46:51,760 --> 01:46:53,480
DEMONSTRATE ABOUT THE PROCESSES

2478
01:46:53,480 --> 01:46:55,760
AND THE TIME LINES REQUIRED

2479
01:46:55,760 --> 01:46:57,480
BETWEEN THE TIME THAT AN

2480
01:46:57,480 --> 01:46:58,960
INVESTIGATOR IS SUBMITTED THAT

2481
01:46:58,960 --> 01:47:00,880
DATA CAN BE MADE ACCESSIBLE SO

2482
01:47:00,880 --> 01:47:07,720
THOSE ARE REALLY IMPORTANT

2483
01:47:07,720 --> 01:47:07,960
POINTS.

2484
01:47:07,960 --> 01:47:08,400
>>BRIAN.

2485
01:47:08,400 --> 01:47:09,400
>>YEAH.

2486
01:47:09,400 --> 01:47:12,800
JUST A SHORT QUESTION.

2487
01:47:12,800 --> 01:47:16,080
AND A COMMENT.

2488
01:47:16,080 --> 01:47:18,200
IN THE STRUCTURAL BIOLOGY AND

2489
01:47:18,200 --> 01:47:20,000
CHEMICAL BIOLOGY FIELDS WE'VE

2490
01:47:20,000 --> 01:47:23,640
BEEN SHARING OUR DATA FOR A LONG

2491
01:47:23,640 --> 01:47:26,680
TIME.

2492
01:47:26,680 --> 01:47:29,600
THE RAW DATA IS THE MAPS ARE

2493
01:47:29,600 --> 01:47:33,760
UPLOADED INTO THE PROTEIN

2494
01:47:33,760 --> 01:47:35,640
DATABASE.

2495
01:47:35,640 --> 01:47:38,040
RAW IMAGES CAN BE UPLOADED INTO

2496
01:47:38,040 --> 01:47:40,880
THE EMPIRE DATABASE AS WELL.

2497
01:47:40,880 --> 01:47:42,920
AND THE QUESTION IS, THOUGH,

2498
01:47:42,920 --> 01:47:47,320
WHEN WE PUBLISH THE PAPERS NOW,

2499
01:47:47,320 --> 01:47:48,960
SORT OF IN THE BIG JOURNALS,

2500
01:47:48,960 --> 01:47:51,400
THEY REQUIRE THE RAW DATA AS

2501
01:47:51,400 --> 01:47:53,840
PART OF THE ACCEPTANCE PROCESS.

2502
01:47:53,840 --> 01:47:56,040
SO THE RAW DATA IS POST WITH THE

2503
01:47:56,040 --> 01:47:57,440
PAPER BASICALLY.

2504
01:47:57,440 --> 01:48:01,280
SO THE QUESTION IS THIS

2505
01:48:01,280 --> 01:48:03,360
REQUIREMENT TO HAVE THE RAW DATA

2506
01:48:03,360 --> 01:48:04,880
AVAILABLE OR DO WE HAVE TO

2507
01:48:04,880 --> 01:48:08,840
REPOST THE RAW DATA TO ANOTHER

2508
01:48:08,840 --> 01:48:09,400
(INAUDIBLE)?

2509
01:48:09,400 --> 01:48:10,880
THAT'S THE QUESTION AND THEN I

2510
01:48:10,880 --> 01:48:11,840
HAVE A COMMENT.

2511
01:48:11,840 --> 01:48:14,240
SO I SHARE THE CONCERN ABOUT THE

2512
01:48:14,240 --> 01:48:17,160
GEO LOCATION DATA BEING SHARED

2513
01:48:17,160 --> 01:48:17,880
WITH ANYONE.

2514
01:48:17,880 --> 01:48:21,600
PARTICULARLY IN THE GOVERNMENT,

2515
01:48:21,600 --> 01:48:24,480
ACTUALLY.

2516
01:48:24,480 --> 01:48:27,560
I'M STRONGLY AGAINST THIS.

2517
01:48:27,560 --> 01:48:29,760
I THINK IT'S A REALLY BAD IDEA.

2518
01:48:29,760 --> 01:48:33,160
I DON'T DO HUMAN CLINICAL

2519
01:48:33,160 --> 01:48:34,000
RESEARCH.

2520
01:48:34,000 --> 01:48:36,720
IT'S ENOUGH THAT APPLE KNOWS

2521
01:48:36,720 --> 01:48:39,840
WHERE I GO, I DON'T REALLY WANT

2522
01:48:39,840 --> 01:48:41,840
THE GOVERNMENT, IF I'M IN A

2523
01:48:41,840 --> 01:48:42,720
CLINICAL TRIAL, FOR WHATEVER, I

2524
01:48:42,720 --> 01:48:43,720
DO NOT WANT THE GOVERNMENT TO

2525
01:48:43,720 --> 01:48:47,960
HAVE ACCESS TO MY GEO LOCATION.

2526
01:48:47,960 --> 01:48:51,960
I THINK IT'S A REALLY BAD IDEA.

2527
01:48:51,960 --> 01:48:57,960
SO, THAT'S ALL I HAVE TO SAY.

2528
01:48:57,960 --> 01:48:59,840
>>SO ON THE QUESTION OF
WHEN

2529
01:48:59,840 --> 01:49:01,800
YOU ARE SHARING DATA AS PART OF

2530
01:49:01,800 --> 01:49:06,160
THE PUN LA INDICATION PROCESS, I

2531
01:49:06,160 --> 01:49:07,800
PUBLICATION IS IT'S HOW IT'S

2532
01:49:07,800 --> 01:49:08,400
SHARED.

2533
01:49:08,400 --> 01:49:09,920
SAY YOU ARE DEPOSIT IN A RE POS

2534
01:49:09,920 --> 01:49:11,640
TORI ALONGSIDE THE METADATA THAT

2535
01:49:11,640 --> 01:49:14,200
YOU NEED TO REUSE THAT DATA, AND

2536
01:49:14,200 --> 01:49:15,800
THAT SOUNDS LIKE IT WOULD

2537
01:49:15,800 --> 01:49:17,760
PROBABLY BE FINDABLE ACCESSIBLE

2538
01:49:17,760 --> 01:49:19,080
AND ENTERSER OPERABLE AND

2539
01:49:19,080 --> 01:49:19,360
REUSABLE.

2540
01:49:19,360 --> 01:49:22,560
>>IF YOU GO TO THE PUBMed

2541
01:49:22,560 --> 01:49:25,360
RECORD, AND YOU CLICK ON THE

2542
01:49:25,360 --> 01:49:26,480
LINK, TYPICALLY THERE'S A LINK

2543
01:49:26,480 --> 01:49:28,200
TO THE DATA RIGHT THERE.

2544
01:49:28,200 --> 01:49:28,840
>>YEAH.

2545
01:49:28,840 --> 01:49:33,400
>>BUT FUR SAY DEPOSITING
IT AND

2546
01:49:33,400 --> 01:49:34,760
THERE'S ONE ANSWER FOR

2547
01:49:34,760 --> 01:49:37,920
EVERYTHING BUT IF IT'S SHARED AS

2548
01:49:37,920 --> 01:49:41,320
WITH SUPPLEMENTAL PUBLICATION

2549
01:49:41,320 --> 01:49:43,240
FILE THAT MAY OR MAIN BE EASY TO

2550
01:49:43,240 --> 01:49:45,600
USE BUT THE POLICY DOESN'T SHARE

2551
01:49:45,600 --> 01:49:47,120
MUCH ON THIS PARTICULAR IN THIS

2552
01:49:47,120 --> 01:49:48,200
PARTICULAR WAY SO IF YOU ARE

2553
01:49:48,200 --> 01:49:49,720
PLANNING ON DEPOSITING IN IT,

2554
01:49:49,720 --> 01:49:53,040
KIND OF SUITABLE LOCATION, THEN

2555
01:49:53,040 --> 01:49:55,200
IT MAKES SENSE TO MENTION THAT

2556
01:49:55,200 --> 01:49:56,920
IN YOUR PLAN.

2557
01:49:56,920 --> 01:49:58,080
WITHOUT KNOWING THE SPECIFICS

2558
01:49:58,080 --> 01:49:59,480
I'M NOT THINKING ON YOUR ISSUES

2559
01:49:59,480 --> 01:49:59,680
THERE.

2560
01:49:59,680 --> 01:50:03,000
>>SCIENCE NATURE AND
INAWE

2561
01:50:03,000 --> 01:50:07,040
REQUIRE YOU TO UP LOAD THE RAW

2562
01:50:07,040 --> 01:50:10,080
DATA.

2563
01:50:10,080 --> 01:50:11,320
(INAUDIBLE).

2564
01:50:11,320 --> 01:50:13,480
IT WOULD SEEM JUST NAIVELY IT

2565
01:50:13,480 --> 01:50:14,800
WOULD SEEM TO ME THAT WOULD

2566
01:50:14,800 --> 01:50:16,080
FULFILL THE REQUIREMENT BECAUSE

2567
01:50:16,080 --> 01:50:17,960
YOU DON'T HAVE TO SUBSCRIBE TO

2568
01:50:17,960 --> 01:50:22,160
THE JOURNAL OF ACCESS THE DATA.

2569
01:50:22,160 --> 01:50:22,880
IT'S THERE.

2570
01:50:22,880 --> 01:50:24,520
EVEN IF YOU ARE NOT SUBSCRIBE TO

2571
01:50:24,520 --> 01:50:25,640
THE JOURNAL.

2572
01:50:25,640 --> 01:50:27,960
YOU CAN GET IT AND YOU CAN GET

2573
01:50:27,960 --> 01:50:32,440
THE PAPER FROM IT.

2574
01:50:32,440 --> 01:50:35,960
SO, WOULDN'T THAT BE ACCEPTABLE?

2575
01:50:35,960 --> 01:50:38,680
ARE WE GOING TO HAVE TO -- IS

2576
01:50:38,680 --> 01:50:41,840
THERE A POLICY ON THIS?

2577
01:50:41,840 --> 01:50:44,240
>>WE DON'T HAVE A
SPECIFIC FAQ

2578
01:50:44,240 --> 01:50:47,440
ON THAT BUT I THINK THE POLICY

2579
01:50:47,440 --> 01:50:48,720
ALLOWS FLEXIBILITY IN WHAT'S PRO

2580
01:50:48,720 --> 01:50:50,680
PRO AT FOR A GIVEN RESEARCH

2581
01:50:50,680 --> 01:50:52,680
PROJECT AND A GIVEN DMS PLAN SO

2582
01:50:52,680 --> 01:50:55,440
IT'S SOMETHING THAT CAN BE

2583
01:50:55,440 --> 01:50:57,920
INCLUDED IN THE PLAN AND

2584
01:50:57,920 --> 01:50:59,160
DISCUSSED AFTER THE (INAUDIBLE)

2585
01:50:59,160 --> 01:51:02,240
SPECIFIC PROJECT.

2586
01:51:02,240 --> 01:51:08,000
>>MARGARITE A AND THEN
JOEL.

2587
01:51:08,000 --> 01:51:14,400
AND IT DEPENDS.

2588
01:51:14,400 --> 01:51:16,360
>>THIS IS SUPER HARD.

2589
01:51:16,360 --> 01:51:20,280
AND THIS IS NOT THE FIRST MAJOR

2590
01:51:20,280 --> 01:51:21,840
CHANGE THAT HAS HAPPENED IN NIH.

2591
01:51:21,840 --> 01:51:23,320
I REMEMBER THINKING I COULD

2592
01:51:23,320 --> 01:51:25,640
NEVER DO MY PROPOSALS AND NOW

2593
01:51:25,640 --> 01:51:27,760
I'M NEVER GOING BACK.

2594
01:51:27,760 --> 01:51:30,320
SO I DON'T ENVY YOU IN THIS JOB

2595
01:51:30,320 --> 01:51:32,240
AND I APPRECIATE ALL THE

2596
01:51:32,240 --> 01:51:35,360
LEARNING APPROACHES YOU ALL ARE

2597
01:51:35,360 --> 01:51:35,760
TAKING.

2598
01:51:35,760 --> 01:51:36,880
I HAVE TWO COMMENTS AND NOT

2599
01:51:36,880 --> 01:51:38,560
QUESTIONS.

2600
01:51:38,560 --> 01:51:40,760
ONE IS, GIVEN WHAT I'M HEARING

2601
01:51:40,760 --> 01:51:42,400
FROM COLLEAGUES, FOLKS ARE GOING

2602
01:51:42,400 --> 01:51:44,480
TO WANT TO KNOW HOW CAN THEY

2603
01:51:44,480 --> 01:51:48,200
APPEAL TO THE DECISION AROUND

2604
01:51:48,200 --> 01:51:50,480
THEIR MAKING -- IF THEY'RE

2605
01:51:50,480 --> 01:51:52,400
MAKING A CASE FOR LIMITING

2606
01:51:52,400 --> 01:51:54,080
SHARING THEIR DATA AND LET'S SAY

2607
01:51:54,080 --> 01:51:56,360
THE P.O. DECIDE IT'S NOT

2608
01:51:56,360 --> 01:51:58,880
APPROPRIATE, WHAT CAN THEY DO

2609
01:51:58,880 --> 01:52:00,040
THEN?

2610
01:52:00,040 --> 01:52:01,320
I SUSPECT AND KNOW THAT THEY'RE

2611
01:52:01,320 --> 01:52:03,920
GOING TO BE FOLKS WHO WANT TO GO

2612
01:52:03,920 --> 01:52:06,120
TO ANOTHER LEVEL TO TRY TO

2613
01:52:06,120 --> 01:52:08,760
ADDRESS THAT AND THEN IF THIS IS

2614
01:52:08,760 --> 01:52:11,360
ALL, IF THE DECISIONS AROUND

2615
01:52:11,360 --> 01:52:13,960
THESE EXCEPTIONS OR LIMITATIONS

2616
01:52:13,960 --> 01:52:15,960
OR FOR LIMITING THE DATA, ARE

2617
01:52:15,960 --> 01:52:18,720
BEING HELD AT THE P.O. LEVEL I

2618
01:52:18,720 --> 01:52:21,600
WOULD ENCOURAGE THE, WITH ANY

2619
01:52:21,600 --> 01:52:23,440
INSTITUTE THAT THE P.O. ARE IN

2620
01:52:23,440 --> 01:52:24,240
CONVERSATIONS WITH EACH OTHER

2621
01:52:24,240 --> 01:52:25,520
BECAUSE THERE'S AMONG MORE

2622
01:52:25,520 --> 01:52:27,120
FRUSTRATING THAN GETTING

2623
01:52:27,120 --> 01:52:28,920
DIFFERENT ANSWERS FROM DIFFERENT

2624
01:52:28,920 --> 01:52:31,240
PEOPLE AND SO JUSTEN SOARING

2625
01:52:31,240 --> 01:52:33,720
THAT THEY'RE ALL SHARING

2626
01:52:33,720 --> 01:52:34,920
INFORMATION AND LEVEL SETTING TO

2627
01:52:34,920 --> 01:52:36,320
MAKE SURE THEY'RE CONSISTENT IN

2628
01:52:36,320 --> 01:52:38,360
HOW THEY'RE MAKING THE DECISIONS

2629
01:52:38,360 --> 01:52:41,120
COULD BE REALLY HELPFUL.

2630
01:52:41,120 --> 01:52:44,720
>>AND JOEL.

2631
01:52:44,720 --> 01:52:48,400
>>JUST THREE QUICK
THINGS.

2632
01:52:48,400 --> 01:52:50,840
I WANT TO ECHO THANKS FOR BOTH

2633
01:52:50,840 --> 01:52:52,320
THE OPEN MINDEDNESS AND THE

2634
01:52:52,320 --> 01:52:53,160
PROCESS OF LEARNING AS WELL AS

2635
01:52:53,160 --> 01:52:55,440
THE TREMENDOUSLY RICH SET OF

2636
01:52:55,440 --> 01:52:57,760
RESOURCES ON-LINE TO HELP WITH

2637
01:52:57,760 --> 01:52:57,960
THIS.

2638
01:52:57,960 --> 01:52:58,760
IT'S VERY, VERY HELPFUL.

2639
01:52:58,760 --> 01:53:01,400
I WOULD UNDERSCORE THE POINT

2640
01:53:01,400 --> 01:53:03,560
ABOUT LINKING THIS TO THE

2641
01:53:03,560 --> 01:53:04,840
EFFICIENCY OF THE GOVERNMENT

2642
01:53:04,840 --> 01:53:06,120
DATASETS, NOT JUST IN THE GAP

2643
01:53:06,120 --> 01:53:06,840
BUT ALL OF THEM.

2644
01:53:06,840 --> 01:53:10,160
I MEAN, THAT ONE OF THE CHARGES

2645
01:53:10,160 --> 01:53:10,640
GETTING DATA UP LOAD

2646
01:53:10,640 --> 01:53:16,080
SECOND-DEGUPLOADED AND USINGDATF

2647
01:53:16,080 --> 01:53:16,760
PUBLICATION IS YOU CAN'T.

2648
01:53:16,760 --> 01:53:18,400
YOU CAN SUBMIT IT BUT IT WON'T

2649
01:53:18,400 --> 01:53:20,280
BE UPLOADED UNTIL ALL KINDS OF

2650
01:53:20,280 --> 01:53:22,880
OTHER STEPS ARE TAKEN THAT YOU

2651
01:53:22,880 --> 01:53:23,640
CAN'T CONTROL AND THERE'S VERY

2652
01:53:23,640 --> 01:53:25,600
SLOW SO I WANT TO ECHO THE POINT

2653
01:53:25,600 --> 01:53:27,800
AND JUST ENCOURAGING LINKING

2654
01:53:27,800 --> 01:53:31,320
THIS TO THE AVAILABILITY AND THE

2655
01:53:31,320 --> 01:53:32,440
EFFICIENCY OF THE RESPONSE

2656
01:53:32,440 --> 01:53:37,840
DATASETS AND THEN ON THE POINT,

2657
01:53:37,840 --> 01:53:41,480
IN GIVING ADVICE ON WHAT TO DO

2658
01:53:41,480 --> 01:53:42,880
WITH SOME OF THE RULES THAT SEEM

2659
01:53:42,880 --> 01:53:45,520
LIKE YOU CAN'T OBEY THEM WITHOUT

2660
01:53:45,520 --> 01:53:48,000
VIOLATING SOME OTHER RULE, IT'S

2661
01:53:48,000 --> 01:53:49,120
A CHALLENGE BECAUSE THERE'S A

2662
01:53:49,120 --> 01:53:50,920
LOT OF THOSE AND SO FREQUENTLY

2663
01:53:50,920 --> 01:53:54,000
THERE ARE THINGS THAT HAVE TO BE

2664
01:53:54,000 --> 01:53:57,720
ADJUDICATED OR ESCALATED BUT

2665
01:53:57,720 --> 01:53:59,360
THEN IT'S UNCLEAR WHO THE

2666
01:53:59,360 --> 01:54:00,640
AUTHORITY IS BECAUSE THE P.O. IS

2667
01:54:00,640 --> 01:54:04,720
ONE AUTHORITY AND SO IS THE

2668
01:54:04,720 --> 01:54:05,640
SUPERVISOR WHOEVER WHAT DATABASE

2669
01:54:05,640 --> 01:54:07,160
YOU ARE WORKING WITH ON THE

2670
01:54:07,160 --> 01:54:09,320
RULES OF THE GOVERNMENT PLAN.

2671
01:54:09,320 --> 01:54:10,920
SO THE COORDINATION THERE

2672
01:54:10,920 --> 01:54:13,720
DECIDING WHO REALLY SHOULD

2673
01:54:13,720 --> 01:54:14,840
ADJUDICATE THESE QUESTIONS IS

2674
01:54:14,840 --> 01:54:16,320
VERY IMPORTANT IN TERMS OF THE

2675
01:54:16,320 --> 01:54:18,480
POLICY AS YOU IMPLEMENT IT AND

2676
01:54:18,480 --> 01:54:19,920
AS YOU SAY, I KNOW THIS IS GOING

2677
01:54:19,920 --> 01:54:21,120
TO BE LEARNING BY EXPERIENCE FOR

2678
01:54:21,120 --> 01:54:22,880
ALL OF US SO I WANT TO

2679
01:54:22,880 --> 01:54:23,520
UNDERSCORE THOSE POINTS.

2680
01:54:23,520 --> 01:54:26,760
THANK YOU, VERY MUCH.

2681
01:54:26,760 --> 01:54:28,600
>>GREAT.

2682
01:54:28,600 --> 01:54:30,240
LOOKS LIKE THAT'S ALL QUESTIONS

2683
01:54:30,240 --> 01:54:32,280
WE HAVE SO JULIA, THANK YOU SO

2684
01:54:32,280 --> 01:54:34,320
MUCH FOR THE VERY INFORMATIVE

2685
01:54:34,320 --> 01:54:35,160
PRESENTATION AND ALL THE WORK

2686
01:54:35,160 --> 01:54:35,880
THAT YOU'VE DID NOT DOING.

2687
01:54:35,880 --> 01:54:38,040
THANK YOU ALL FOR YOUR COMMENTS.

2688
01:54:38,040 --> 01:54:42,080
WE HAVE A BREAK NOW UNTIL 2:30.

2689
01:54:42,080 --> 01:54:43,920
SO, ENJOY.

2690
01:54:43,920 --> 01:54:46,120
CATCH UP ON E-MAILS, THANK YOU.

2691
01:54:46,120 --> 01:54:51,880
BYE-BYE.

2692
01:54:51,880 --> 01:54:53,760
>>THANK YOU FOR YOUR

2693
01:54:53,760 --> 01:54:54,320
FORBEARANCE THIS AFTERNOON.

2694
01:54:54,320 --> 01:54:56,080
I'M SORRY I COULDN'T BE WITH YOU

2695
01:54:56,080 --> 01:54:57,240
IN-PERSON TO START THE MEETING

2696
01:54:57,240 --> 01:54:58,400
AND I HAD TO MISS MUCH OF THE

2697
01:54:58,400 --> 01:54:59,800
FIRST HALF OF THE MEETING FOR

2698
01:54:59,800 --> 01:55:01,680
ANOTHER EVENT THAT WAS TAKING

2699
01:55:01,680 --> 01:55:02,600
PLACE ON AMOUNT PUSS BUT I'M

2700
01:55:02,600 --> 01:55:06,200
REALLY PLEASED TO JOIN YOU

2701
01:55:06,200 --> 01:55:11,840
TODAY.

2702
01:55:11,840 --> 01:55:12,880
>> Joshua Gordon: GIVE
YOU THE

2703
01:55:12,880 --> 01:55:15,680
UPDATE FROM MY PERSPECTIVE AND

2704
01:55:15,680 --> 01:55:16,880
STUFF PUTTING IT TOGETHER.

2705
01:55:16,880 --> 01:55:18,480
I'M EXCITED TO WHAT WE HAVE TO

2706
01:55:18,480 --> 01:55:20,120
TALK ABOUT THAT INCLUDES

2707
01:55:20,120 --> 01:55:24,120
RESOURCES THAT WE HOPE WILL HELP

2708
01:55:24,120 --> 01:55:27,360
OUR INVESTIGATORS AND HEARING

2709
01:55:27,360 --> 01:55:28,400
THE PUBLIC COMMENT RETURN NOW

2710
01:55:28,400 --> 01:55:35,360
THAT WE ARE IN THIS HYBRID MODE.

2711
01:55:35,360 --> 01:55:35,840
SO THANK YOU AGAIN.

2712
01:55:35,840 --> 01:55:41,560
NOT JOINING THE AUDIO.

2713
01:55:41,560 --> 01:55:42,920
FOR THE OPPORTUNITY TO TELL YOU

2714
01:55:42,920 --> 01:55:45,400
WHAT IS HAPPENING AROUND THE NIH

2715
01:55:45,400 --> 01:55:47,720
AND NIMH.

2716
01:55:47,720 --> 01:55:48,680
LET'S SEE.

2717
01:55:48,680 --> 01:55:49,720
WHO IS RUNNING THIS SLIDES.

2718
01:55:49,720 --> 01:55:54,320
SHOULD I DO IT FROM HERE?

2719
01:55:54,320 --> 01:55:56,640
>>THEY'RE RUNNING IT.

2720
01:55:56,640 --> 01:56:07,160
I'LL WAIT FOR THEM TO APPEAR.

2721
01:56:20,560 --> 01:56:21,280
HERE WE GO.

2722
01:56:21,280 --> 01:56:23,480
SO IF I CAN HAVE THE NEXT SLIDE.

2723
01:56:23,480 --> 01:56:24,480
PLEASE.

2724
01:56:24,480 --> 01:56:26,800
SO, AS USUAL FROM MY TALK IT'S A

2725
01:56:26,800 --> 01:56:28,720
PACKED AGENDA, I'LL TALK TO YOU

2726
01:56:28,720 --> 01:56:29,760
ABOUT SOME CONGRESSIONAL

2727
01:56:29,760 --> 01:56:31,320
INTERACTIONS APPROPRIATIONS AND

2728
01:56:31,320 --> 01:56:32,200
BUDGET UPDATES.

2729
01:56:32,200 --> 01:56:34,360
AS I MENTIONED LAST TIME,

2730
01:56:34,360 --> 01:56:35,960
CONTINUED GOODS NEWS IN TERMS OF

2731
01:56:35,960 --> 01:56:38,240
INTEREST IN THE WHITE HOUSE AND

2732
01:56:38,240 --> 01:56:41,680
ALSO UPDATES AND HHS AND AROUND

2733
01:56:41,680 --> 01:56:43,000
THE NIH SOME NEWS TO KNOW FROM

2734
01:56:43,000 --> 01:56:44,240
OUR INSTITUTE AND I'LL CLOSE

2735
01:56:44,240 --> 01:56:47,520
WITH A COUPLE OF HIGHLIGHTS

2736
01:56:47,520 --> 01:56:49,440
BEFORE REMINDING YOU ABOUT THE

2737
01:56:49,440 --> 01:56:55,920
75th ANNIVERSARY TO END.

2738
01:56:55,920 --> 01:56:59,200
IS WE'VE HAD A BUSY SPRING AND

2739
01:56:59,200 --> 01:57:00,520
OF COURSE THAT IS TYPICAL FOR

2740
01:57:00,520 --> 01:57:02,800
THE LEAD INTO TO THE PREPARATION

2741
01:57:02,800 --> 01:57:04,640
SEASON AND IT'S A TYPICAL IN

2742
01:57:04,640 --> 01:57:06,480
TERMS OF AS I'VE BEEN MENTIONING

2743
01:57:06,480 --> 01:57:08,920
NOW FOR A WHILE, CONTINUED

2744
01:57:08,920 --> 01:57:11,560
INCREASES AND INTEREST AMONGST

2745
01:57:11,560 --> 01:57:12,240
CONGRESSIONAL MEMBERS AND

2746
01:57:12,240 --> 01:57:14,000
HEARING FROM NIMH BOTH IN ELSE

2747
01:57:14,000 --> 01:57:18,280
IT O TRYING TO WHAT WE NEED TO

2748
01:57:18,280 --> 01:57:19,880
UNDERSTAND OUR RESEARCH AND

2749
01:57:19,880 --> 01:57:21,440
UNDERSTANDING WHAT INFORMATION

2750
01:57:21,440 --> 01:57:31,920
WE CAN PROVIDE BETWEEN MYSELF

2751
01:57:33,400 --> 01:57:34,720
AND OTHER STAFF WE PARTICIPATED

2752
01:57:34,720 --> 01:57:36,480
IN SEVEN DIFFERENT CONGRESSIONAL

2753
01:57:36,480 --> 01:57:37,160
BRIEFINGS WITH MEMBERS AND

2754
01:57:37,160 --> 01:57:37,560
STAFF.

2755
01:57:37,560 --> 01:57:39,600
THE TOPICS INCLUDE SUICIDE

2756
01:57:39,600 --> 01:57:41,480
PREVENTION, HEALTH DISPARITIES,

2757
01:57:41,480 --> 01:57:43,560
SERIOUS MENTAL ILLNESS, SOCIAL

2758
01:57:43,560 --> 01:57:52,080
MEDIA AND MORE AND ONE OF THOSE

2759
01:57:52,080 --> 01:57:53,040
THEY'RE TWO SEPARATE CAUCUSES IN

2760
01:57:53,040 --> 01:57:55,800
THE HOUSE AND THEY CAME TOGETHER

2761
01:57:55,800 --> 01:57:59,320
WHERE IT WAS MYSELF AND SOMEONE

2762
01:57:59,320 --> 01:58:02,360
FROM THE OFFICE OF NATIONAL DRUG

2763
01:58:02,360 --> 01:58:04,800
CONTROL AND POLICY AND REALLY

2764
01:58:04,800 --> 01:58:07,280
TALKING ABOUT ALL THINGS, MENTAL

2765
01:58:07,280 --> 01:58:09,120
HEALTH AND SUBSTANCE ABUSE AND

2766
01:58:09,120 --> 01:58:16,200
IT WAS REALLY A VERY RICH EFFORT

2767
01:58:16,200 --> 01:58:17,440
AND IT WENT ON.

2768
01:58:17,440 --> 01:58:19,880
WE ARE IN APPROPRIATIONS SEASON.

2769
01:58:19,880 --> 01:58:25,120
AS THE HOUSE AND SENATE BEGIN TO

2770
01:58:25,120 --> 01:58:31,840
CONTEMPLATE THE OF 2024 BUDGET.

2771
01:58:31,840 --> 01:58:33,200
THERE'S BEEN HEARING BETWEEN

2772
01:58:33,200 --> 01:58:35,600
MARCH AND MAY WHICH INCLUDED THE

2773
01:58:35,600 --> 01:58:40,120
OF THE SECRETARY OF HHS OF

2774
01:58:40,120 --> 01:58:50,480
COURSE AND ALSO IT WAS

2775
01:59:04,000 --> 01:59:05,720
PRIVILEGED HE ANSWERED A

2776
01:59:05,720 --> 01:59:07,440
UNPRESIDENT NUMBER OF QUESTIONS

2777
01:59:07,440 --> 01:59:07,920
ON MENTAL HEALTH.

2778
01:59:07,920 --> 01:59:09,320
INTEREST IN THE SAME TOPICS THAT

2779
01:59:09,320 --> 01:59:12,120
I JUST MENTIONED BEFORE AND ALSO

2780
01:59:12,120 --> 01:59:13,440
INTEREST IN UNDERSTANDING MORE

2781
01:59:13,440 --> 01:59:15,720
ABOUT OUR PRECISION PSYCHIATRY

2782
01:59:15,720 --> 01:59:16,880
INITIATIVES WHICH WERE MENTIONED

2783
01:59:16,880 --> 01:59:20,880
IN THE PRESIDENT'S JUDGE ET AS

2784
01:59:20,880 --> 01:59:26,000
WELL AS OUR INITIATIVES OF YOUTH

2785
01:59:26,000 --> 01:59:27,200
MENTAL HEALTH MORE BROADLY.

2786
01:59:27,200 --> 01:59:29,480
IT WAS A POSITIVE GIVE-AND-TAKE

2787
01:59:29,480 --> 01:59:37,440
WITH THE SENATORS REALLY VOICING

2788
01:59:37,440 --> 01:59:40,720
THEIR SUPPORT FOR NIH.

2789
01:59:40,720 --> 01:59:41,880
OF COURSE WE DON'T KNOW WHERE

2790
01:59:41,880 --> 01:59:44,000
THAT WILL PUT THE BUDGET FOR

2791
01:59:44,000 --> 01:59:46,040
2024 BUT I WANT TO GO OVER SOME

2792
01:59:46,040 --> 01:59:47,720
UPDATES THROUGH THE 2023 BUDGET.

2793
01:59:47,720 --> 01:59:48,720
NEXT SLIDE.

2794
01:59:48,720 --> 01:59:50,320
WHICH NOW WE'RE WELL INTO OF

2795
01:59:50,320 --> 01:59:55,200
COURSE THIS REPRESENTS THE LAST

2796
01:59:55,200 --> 01:59:56,360
FULL COUNCIL FOR GRANTS AND IT

2797
01:59:56,360 --> 02:00:01,400
WILL BE FUNDED FOR 2023 AND WE

2798
02:00:01,400 --> 02:00:02,640
DO GRANTS IN AUGUST AND

2799
02:00:02,640 --> 02:00:04,200
SEPTEMBER THAT COME IN ADVANCE

2800
02:00:04,200 --> 02:00:05,400
OF THE OCTOBER COUNCIL.

2801
02:00:05,400 --> 02:00:07,640
ON DECEMBER 29th, LAST TIME,

2802
02:00:07,640 --> 02:00:09,600
PRESIDENT JOE BIDEN SIGNED INTO

2803
02:00:09,600 --> 02:00:12,920
LAW THE COMBINED OR CONSOLIDATED

2804
02:00:12,920 --> 02:00:14,760
APPROPRIATIONS ACT WHICH GAVE

2805
02:00:14,760 --> 02:00:16,920
$2.3 BILLION TO THE NATIONAL

2806
02:00:16,920 --> 02:00:18,440
INSTITUTE OF MENTAL HEALTH

2807
02:00:18,440 --> 02:00:20,960
INCLUDING A LARGE FROM THE CURES

2808
02:00:20,960 --> 02:00:23,200
ACT TO HELP FUND THE AMBITIOUS

2809
02:00:23,200 --> 02:00:25,680
NOT AND BRAIN INITIATIVE.

2810
02:00:25,680 --> 02:00:30,760
AND NOTE, TWO LINE ITEMS IN

2811
02:00:30,760 --> 02:00:31,760
THERE, $25 MILLION TO OUR

2812
02:00:31,760 --> 02:00:33,400
INSTITUTE TO EXPAND OUR RESEARCH

2813
02:00:33,400 --> 02:00:34,680
ON COVID-19 AND MENTAL HEALTH.

2814
02:00:34,680 --> 02:00:35,920
YOU WILL SEE SOME OF THOSE

2815
02:00:35,920 --> 02:00:37,880
GRANTS IN THE PORTFOLIO THAT WE

2816
02:00:37,880 --> 02:00:38,920
REVIEWED TOMORROW AND CLOSED

2817
02:00:38,920 --> 02:00:39,440
SESSION.

2818
02:00:39,440 --> 02:00:44,280
IT ALSO INCLUDES AN INCREASE OF

2819
02:00:44,280 --> 02:00:46,560
$5 MILLION FOR APPROACHES AND

2820
02:00:46,560 --> 02:00:50,800
SERVICE DELIVERY AND WE'ROUSING

2821
02:00:50,800 --> 02:00:53,200
THIS AND OTHER APPROACHES AND

2822
02:00:53,200 --> 02:00:57,480
SYSTEMS DELIVERY.

2823
02:00:57,480 --> 02:00:59,240
NEXT SLIDE.

2824
02:00:59,240 --> 02:01:01,680
THIS IS THE COMBINED NUMBER OF

2825
02:01:01,680 --> 02:01:02,520
APPLICATIONS AND NUMBER OF

2826
02:01:02,520 --> 02:01:07,160
GRANTS AWARDED THAT WE HAVE THE

2827
02:01:07,160 --> 02:01:09,760
LAST SIX YEARS AND INCLUSIVE

2828
02:01:09,760 --> 02:01:13,520
LAST YEAR 2022 AND AN ESTIMATED

2829
02:01:13,520 --> 02:01:14,840
AMOUNT FOR 2023 AND OF COURSE

2830
02:01:14,840 --> 02:01:17,280
WE'RE NOT FINISHED FOR 2023 BUT

2831
02:01:17,280 --> 02:01:18,200
IT'S ESTIMATED.

2832
02:01:18,200 --> 02:01:22,440
YOU WILL NOTE WE SEE SUSTAINED

2833
02:01:22,440 --> 02:01:24,880
INTEREST AND WITH THE GRANT

2834
02:01:24,880 --> 02:01:29,080
NUMBERS AND SLIGHTLY LAST YEAR

2835
02:01:29,080 --> 02:01:29,880
AND WE HAVE APPROXIMATELY

2836
02:01:29,880 --> 02:01:31,680
SIMILAR MEMBERS OF GRANTS AWARD

2837
02:01:31,680 --> 02:01:33,400
AND THE ABSOLUTE NUMBER IS A

2838
02:01:33,400 --> 02:01:35,480
SLIGHT DECREASE AND DUE TO THE

2839
02:01:35,480 --> 02:01:39,000
INCREASE IN THE SIZE OF AWARDS.

2840
02:01:39,000 --> 02:01:40,280
PARTICULARLY TRUE OF THE BRAIN

2841
02:01:40,280 --> 02:01:41,760
INITIATIVE AWARDS THAT WE GIVE

2842
02:01:41,760 --> 02:01:47,040
OUT AS WELL AND SO THAT IS THE

2843
02:01:47,040 --> 02:01:49,040
REASONS WHY AND AND WE SEE A

2844
02:01:49,040 --> 02:01:50,840
SLIGHT DECREASE IN THE NUMBER OF

2845
02:01:50,840 --> 02:01:52,200
AWARDS WE ANTICIPATE GIVING IN

2846
02:01:52,200 --> 02:01:54,920
2023.

2847
02:01:54,920 --> 02:01:55,680
NEXT SLIDE.

2848
02:01:55,680 --> 02:01:57,320
THIS IS THE CHART OF THE BUDGET

2849
02:01:57,320 --> 02:02:05,400
THAT I'VE BEEN SHOWING YOU FOR A

2850
02:02:05,400 --> 02:02:07,800
WHILE YOU CAN SEE THE BRAIN

2851
02:02:07,800 --> 02:02:10,880
INITIATIVE FROM THE CURES ACT.

2852
02:02:10,880 --> 02:02:13,400
THIS IS NOT -- DID NOT RESULT IN

2853
02:02:13,400 --> 02:02:18,000
THE TOTAL DOLLARS TO NMIH AND

2854
02:02:18,000 --> 02:02:21,400
SPENDING O THE BRAIN INITIATIVE

2855
02:02:21,400 --> 02:02:25,080
AND THE BULK WAS MADE IN A

2856
02:02:25,080 --> 02:02:28,240
DECREASE HITTEN THERE WHICH SAY

2857
02:02:28,240 --> 02:02:31,880
SLIGHT BLUE, IT'S PART OF OUR

2858
02:02:31,880 --> 02:02:33,880
BASE BUDGET THAT WE'VE BEEN

2859
02:02:33,880 --> 02:02:34,560
SPENDING ON THE BRAIN INITIATIVE

2860
02:02:34,560 --> 02:02:41,960
SINCE ITS INCEPTION IN 2016.

2861
02:02:41,960 --> 02:02:46,560
SO, ACT APPROPRIATIONS AS

2862
02:02:46,560 --> 02:02:48,400
OPPOSED TO GENERAL

2863
02:02:48,400 --> 02:02:49,120
APPROPRIATIONS BY CONGRESS.

2864
02:02:49,120 --> 02:02:50,840
YOU WILL SEE AGAIN, FOR I THINK

2865
02:02:50,840 --> 02:02:53,400
IT'S SEVEN STRAIGHT YEARS, THE

2866
02:02:53,400 --> 02:02:55,280
BUYING PAUSH OF NIMH SPONSORED

2867
02:02:55,280 --> 02:02:57,440
RESEARCH HAS INCREASED SO WE ARE

2868
02:02:57,440 --> 02:02:58,760
KEEPING ABOVE INFLATION EVEN

2869
02:02:58,760 --> 02:03:01,400
WITH THE SIGNIFICANT INCREASE IN

2870
02:03:01,400 --> 02:03:04,080
INFLATION AND THE PAST YEAR AND

2871
02:03:04,080 --> 02:03:08,560
THE MORE MODEST INCREASE IN OUR

2872
02:03:08,560 --> 02:03:11,840
BUDGET.

2873
02:03:11,840 --> 02:03:14,520
I HAVE IDEA AND SUPPORT FROM

2874
02:03:14,520 --> 02:03:17,760
CONGRESS AND BOTH HOUSES ARE

2875
02:03:17,760 --> 02:03:19,160
INTERESTED IN SUPPORT FROM

2876
02:03:19,160 --> 02:03:20,240
ROBUST AND BIGGER ISSUES AT PLAY

2877
02:03:20,240 --> 02:03:21,800
IN THE CONGRESSIONAL DISCUSSIONS

2878
02:03:21,800 --> 02:03:24,080
OVER THE BUDGET LINE TO SEE HOW

2879
02:03:24,080 --> 02:03:25,720
IT PLAYS OUT IN THE COMING

2880
02:03:25,720 --> 02:03:28,920
MONTHS.

2881
02:03:28,920 --> 02:03:30,520
NEXT SLIDE.

2882
02:03:30,520 --> 02:03:32,480
AS A FORESHADOWING OF THAT

2883
02:03:32,480 --> 02:03:35,200
BUDGET DISCUSSION ON MARCH 9

2884
02:03:35,200 --> 02:03:37,480
THE, THE PRESIDENT RELEASED THE

2885
02:03:37,480 --> 02:03:40,320
BUDGET REQUEST FOR FISCAL YEAR

2886
02:03:40,320 --> 02:03:42,440
2024, IT ESSENTIALLY PROPOSES A

2887
02:03:42,440 --> 02:03:48,040
VERY MODEST INCREASE FROM NIH OF

2888
02:03:48,040 --> 02:03:50,360
$920 MILLION OVER 1/5 OF THAT

2889
02:03:50,360 --> 02:03:51,400
BUDGET INCREASE THE PRESIDENT

2890
02:03:51,400 --> 02:03:53,720
PROPOSED TO COME TO THE NIMH

2891
02:03:53,720 --> 02:03:58,000
THAT WOULD BE A NEAR 10%

2892
02:03:58,000 --> 02:04:02,040
INCREASE IN OUR NON BRAIN BUDGET

2893
02:04:02,040 --> 02:04:02,880
AND SPECIFICALLY AROUND

2894
02:04:02,880 --> 02:04:09,800
PRIORITIES THAT WE IDENTIFIED

2895
02:04:09,800 --> 02:04:14,640
WITH TREE, THESE ARE INITIATIVES

2896
02:04:14,640 --> 02:04:16,720
THAT YOU ALL APPROVED ALREADY IN

2897
02:04:16,720 --> 02:04:17,760
THE PAST AND OTHER INITIATIVES

2898
02:04:17,760 --> 02:04:25,400
THAT WE PLAN TO BRING FORWARD.

2899
02:04:25,400 --> 02:04:27,480
TO DEVELOP NOVEL TREATMENTS AND

2900
02:04:27,480 --> 02:04:29,600
SPECIFIC NOT SET ASIDE

2901
02:04:29,600 --> 02:04:30,440
$20 MILLION FOR MENTAL HEALTH

2902
02:04:30,440 --> 02:04:32,200
IMPACT OF SOCIAL MEDIA AND

2903
02:04:32,200 --> 02:04:33,600
$50 MILLION TO SUPPORT THE

2904
02:04:33,600 --> 02:04:35,640
CHRISTIAN PSYCHIATRY INITIATIVE

2905
02:04:35,640 --> 02:04:37,960
THAT WE'VE BEGUN AND HOPE TO

2906
02:04:37,960 --> 02:04:39,360
EXPAND IF WE RECEIVE THIS

2907
02:04:39,360 --> 02:04:40,520
INCREASE IN APPROPRIATIONS.

2908
02:04:40,520 --> 02:04:42,800
THIS IS THE PRESIDENT'S REQUEST.

2909
02:04:42,800 --> 02:04:49,120
WE ALSO HAD THE CHANCE TO MEET

2910
02:04:49,120 --> 02:04:51,080
WITH STAFF OF THE HOUSE AND

2911
02:04:51,080 --> 02:04:52,440
SENATE TO EXPLAIN THIS REQUEST

2912
02:04:52,440 --> 02:04:54,560
AND TO PROVIDE WHAT IS CALLED A

2913
02:04:54,560 --> 02:04:55,800
PROFESSIONAL JUDGMENT BUDGET

2914
02:04:55,800 --> 02:04:59,880
WHICH GOES BEYOND THIS REQUEST

2915
02:04:59,880 --> 02:05:01,520
AND TO SAY WHAT WE NEED IF WE

2916
02:05:01,520 --> 02:05:03,000
WANTED TO MAXIMIZE OUR ADDRESSES

2917
02:05:03,000 --> 02:05:04,880
OF CHALLENGING AND SERIOUS

2918
02:05:04,880 --> 02:05:07,480
MENTAL ILLNESS AND SO, WE'LL SEE

2919
02:05:07,480 --> 02:05:08,640
WHAT CONGRESS DOES WITH BOTH OF

2920
02:05:08,640 --> 02:05:09,840
INFORMATION THAT WE GAVE THEM

2921
02:05:09,840 --> 02:05:11,520
THROUGH THAT PROFESSIONAL

2922
02:05:11,520 --> 02:05:12,360
JUDGMENT BUDGET AS WELL AS AS

2923
02:05:12,360 --> 02:05:14,320
THE PRESIDENT'S OWN BUDGET

2924
02:05:14,320 --> 02:05:17,560
REQUEST.

2925
02:05:17,560 --> 02:05:21,920
NEXT SLIDE.

2926
02:05:21,920 --> 02:05:23,720
SO NOT MUCH MORE TO DO WITH

2927
02:05:23,720 --> 02:05:26,120
20924 BUDGET EX SEPARATE AND

2928
02:05:26,120 --> 02:05:27,960
WE'LL GO OVER TO OTHER NEWS FROM

2929
02:05:27,960 --> 02:05:30,320
THE WHITE HOUSE AND HHS AND NIH.

2930
02:05:30,320 --> 02:05:32,280
FIRST SOME ANNOUNCEMENTS AND

2931
02:05:32,280 --> 02:05:35,400
INITIATIVES.

2932
02:05:35,400 --> 02:05:42,840
NEXT SLIDE.

2933
02:05:42,840 --> 02:05:44,520
THE WHITE HOUSE PUT OUT A REPORT

2934
02:05:44,520 --> 02:05:45,600
ACROSS THE GOVERNMENT AND I WANT

2935
02:05:45,600 --> 02:05:49,400
TO MENTION THE WORK OF THE

2936
02:05:49,400 --> 02:05:51,480
SHELLY AND BOB SIGN SEN WHO

2937
02:05:51,480 --> 02:05:54,120
WORKED HARD WITH MEMBERS OF OSDP

2938
02:05:54,120 --> 02:05:55,600
AND REALLY OTHERS ACROSS

2939
02:05:55,600 --> 02:05:59,760
GOVERNMENT AND BACKED UP WHICH

2940
02:05:59,760 --> 02:06:02,600
MANY, MANY DIFFERENT PROGRAM

2941
02:06:02,600 --> 02:06:06,080
STAFF TONE SURE THAT THESE

2942
02:06:06,080 --> 02:06:07,360
PRIORITIES MET OR AGREED WITH

2943
02:06:07,360 --> 02:06:08,920
MOST OF ANYMORE'S PRIORITIES AS

2944
02:06:08,920 --> 02:06:10,920
WELL AND THE AREAS OF 'EM IF SIS

2945
02:06:10,920 --> 02:06:13,400
AND GOVERNMENT WIDE PERSPECTIVE

2946
02:06:13,400 --> 02:06:14,440
INCLUDE MENTAL HEALTH INEQUITIES

2947
02:06:14,440 --> 02:06:16,080
AND UNDERSTANDING DIGITAL MENTAL

2948
02:06:16,080 --> 02:06:18,480
HEALTH INTERVENTIONS AND

2949
02:06:18,480 --> 02:06:19,000
SUPPORTING MENTAL HEALTH

2950
02:06:19,000 --> 02:06:20,680
WORKFORCE AND THE REPORT

2951
02:06:20,680 --> 02:06:21,840
HIGHLIGHTS SEVERAL RESEARCH

2952
02:06:21,840 --> 02:06:24,400
INITIATIVES THAT ARE ALREADY

2953
02:06:24,400 --> 02:06:25,840
UNDERWAY AS WELL AS PROPOSING TO

2954
02:06:25,840 --> 02:06:27,320
ENHANCE SOME OF THE ONCE THAT WE

2955
02:06:27,320 --> 02:06:31,520
HOPE TO DO IN THE FUTURE.

2956
02:06:31,520 --> 02:06:33,600
NEXT SLIDE.

2957
02:06:33,600 --> 02:06:34,880
THE WHITE HOUSE HAS BEEN

2958
02:06:34,880 --> 02:06:36,160
THINKING ABOUT MENTAL HEALTH

2959
02:06:36,160 --> 02:06:37,400
IT'S ALSO BEEN THINKING ABOUT

2960
02:06:37,400 --> 02:06:38,440
RESEARCH IN GENERAL.

2961
02:06:38,440 --> 02:06:40,160
AS YOU KNOW IN 2022 THE WHITE

2962
02:06:40,160 --> 02:06:41,240
HOUSE OFFICE OF SCIENCE AND

2963
02:06:41,240 --> 02:06:43,640
TECHNOLOGY POLICY RELEASED A

2964
02:06:43,640 --> 02:06:45,640
MEMORANDUM ON ENSURING FREE AND

2965
02:06:45,640 --> 02:06:47,040
IMMEDIATE EQUITABLE ACCESS TO

2966
02:06:47,040 --> 02:06:51,160
FEDERAL FUNDED RESEARCH AND THIS

2967
02:06:51,160 --> 02:06:52,320
MEMORANDUM AND A EXECUTIVE ORDER

2968
02:06:52,320 --> 02:06:54,280
FROM THE PRESIDENT ESTABLISHES

2969
02:06:54,280 --> 02:06:58,040
THAT NIMH SUPPORTED RESEARCH

2970
02:06:58,040 --> 02:07:01,120
WILL NEED TO BE IMPROVE PUBLIC

2971
02:07:01,120 --> 02:07:03,120
ACCESS TO PUBLICATIONS INCLUDING

2972
02:07:03,120 --> 02:07:06,680
ELIMINATING THE 12-MONTH WAITING

2973
02:07:06,680 --> 02:07:08,560
PERIOD FOR RESEARCH TO BE

2974
02:07:08,560 --> 02:07:08,960
PUBLICLY ACCESSED.

2975
02:07:08,960 --> 02:07:10,400
WE HAVE A FEW YEARS BEFORE THIS

2976
02:07:10,400 --> 02:07:12,040
TAKES EFFECT BUT WE WANT TO MAKE

2977
02:07:12,040 --> 02:07:15,400
SURE THAT OUR RESEARCHERS AND

2978
02:07:15,400 --> 02:07:17,240
THE JOURNALS AND THAT EVERYONE

2979
02:07:17,240 --> 02:07:19,760
ELSE IN THE KNOWS WHAT TO HE

2980
02:07:19,760 --> 02:07:21,440
EXPECT AND WE HAVE LISTENING

2981
02:07:21,440 --> 02:07:23,120
SESSIONS AND SEEK PUBLIC ACCESS

2982
02:07:23,120 --> 02:07:25,640
AND PUBLIC GUIDANCE ON OUR PLAN

2983
02:07:25,640 --> 02:07:27,280
TO ENHANCE PUBLIC ACCESS

2984
02:07:27,280 --> 02:07:28,560
INCLUDING A LISTENING SESSION

2985
02:07:28,560 --> 02:07:33,600
THAT TOOK PLACE IN APRIL.

2986
02:07:33,600 --> 02:07:35,800
THE NIH HAS ALSO DEVELOPED A

2987
02:07:35,800 --> 02:07:38,080
STRATEGIC PLAN FOR DIVERSITY

2988
02:07:38,080 --> 02:07:40,040
EQUITY INCLUSION AND

2989
02:07:40,040 --> 02:07:41,400
ACCESSIBILITY COVERING THE

2990
02:07:41,400 --> 02:07:43,480
FISCAL YEAR THROUGH 2027.

2991
02:07:43,480 --> 02:07:46,680
THIS STRATEGIC PLAN ARTICULATES

2992
02:07:46,680 --> 02:07:50,000
NIH'S COMMITMENT TO EMBRACING,

2993
02:07:50,000 --> 02:07:53,320
STRENGTHENING AND INTEGRATING

2994
02:07:53,320 --> 02:07:55,280
DEIA INTRAMURALLY AND

2995
02:07:55,280 --> 02:07:56,120
EXTRAMURALLY AND ENCOURAGE YOU

2996
02:07:56,120 --> 02:07:58,480
TO TAKE A LOOK AT THIS STRATEGIC

2997
02:07:58,480 --> 02:07:59,240
PLAN.

2998
02:07:59,240 --> 02:08:00,000
MANY OF THE PRIORITIES

2999
02:08:00,000 --> 02:08:01,080
IDENTIFIED IN HERE ARE THINGS

3000
02:08:01,080 --> 02:08:03,680
THAT NIMH HAS ALREADY BEEN

3001
02:08:03,680 --> 02:08:05,440
WORKING ON AND HAS ALREADY

3002
02:08:05,440 --> 02:08:06,800
INCORPORATED TO ITS STRATEGIC

3003
02:08:06,800 --> 02:08:08,920
PLAN ALTHOUGH AS I SAY IN A

3004
02:08:08,920 --> 02:08:15,760
MOMENT, WE JUST FINISHED AN

3005
02:08:15,760 --> 02:08:26,280
UPDATE ANNOUNCED IN A NEW PRIZE

3006
02:08:33,440 --> 02:08:36,080
COMPETITION FOR INSTITUTIONAL IN

3007
02:08:36,080 --> 02:08:38,480
DEIA ACTIVITIES AND IT WAS

3008
02:08:38,480 --> 02:08:40,080
ANNOUNCED APRIL 4th AND

3009
02:08:40,080 --> 02:08:41,040
DEADLINE IS THIS SEPTEMBER AND

3010
02:08:41,040 --> 02:08:43,080
FOR THOSE WHO ARE INTERESTED IN

3011
02:08:43,080 --> 02:08:44,920
HELPING THEIR INSTITUTION APPLY

3012
02:08:44,920 --> 02:08:49,680
FOR THESE PRIZES, THE -- THERE'S

3013
02:08:49,680 --> 02:08:50,960
AN INFORMATIONAL WEBINAR

3014
02:08:50,960 --> 02:08:52,080
TOMORROW AT 1:00.

3015
02:08:52,080 --> 02:08:54,040
YOU CAN LOOK ON THE NIH WEBSITE

3016
02:08:54,040 --> 02:08:59,800
TO FIND OUT MORE ABOUT IT.

3017
02:08:59,800 --> 02:09:01,880
THE ALL OF US RESEARCH PROGRAM

3018
02:09:01,880 --> 02:09:04,080
PARTNERING WITH NIMH TO HELP US

3019
02:09:04,080 --> 02:09:06,720
IN OUR EFFORTS TO UNDERSTAND HOW

3020
02:09:06,720 --> 02:09:07,680
BEHAVIORAL TESTS MIGHT BE ABLE

3021
02:09:07,680 --> 02:09:10,280
TO INFORM DECISIONS ABOUT --

3022
02:09:10,280 --> 02:09:11,680
DIAGNOSTICS AND DECISIONS ABOUT

3023
02:09:11,680 --> 02:09:12,720
CLINICAL PREDICTION.

3024
02:09:12,720 --> 02:09:15,120
THE ALL OF US HAS BEEN REALLY

3025
02:09:15,120 --> 02:09:18,320
BUSY RAMPING UP THEIR ENROLLMENT

3026
02:09:18,320 --> 02:09:20,160
AND IMPORTANTLY RELEASING DATA

3027
02:09:20,160 --> 02:09:21,760
PACKAGES AND DATA PLATFORMS AS

3028
02:09:21,760 --> 02:09:24,160
WELL AS DATA ANALYTICS PLATFORMS

3029
02:09:24,160 --> 02:09:26,160
AND ON MARCH 29th THROUGH THE

3030
02:09:26,160 --> 02:09:27,560
31st THEY HOST AID VIRTUAL

3031
02:09:27,560 --> 02:09:28,720
RESEARCHERS CONVENTION TO

3032
02:09:28,720 --> 02:09:30,000
PROVIDE AN OPPORTUNITY FOR

3033
02:09:30,000 --> 02:09:31,720
RESEARCHERS WHO USE ALL OF US

3034
02:09:31,720 --> 02:09:33,440
DATA AND TOOLS TO SHOWCASE THEIR

3035
02:09:33,440 --> 02:09:35,360
WORK AND TO LEARN BEST

3036
02:09:35,360 --> 02:09:36,840
PRACTICES.

3037
02:09:36,840 --> 02:09:38,640
AND FOR THOSE DATA SCIENTISTS

3038
02:09:38,640 --> 02:09:40,520
OUT THERE AND IN THE UNIVERSE I

3039
02:09:40,520 --> 02:09:42,600
WILL REMIND THEM OF DATA I'VE

3040
02:09:42,600 --> 02:09:43,960
SHOWN IN THE PAST AND OF THE

3041
02:09:43,960 --> 02:09:46,160
TALK WE HEARD FROM ALL OF US

3042
02:09:46,160 --> 02:09:47,000
RECENTLY WHERE IT'S VERY CLEAR

3043
02:09:47,000 --> 02:09:49,120
THAT THE ENROLLMENT IS INCLUSIVE

3044
02:09:49,120 --> 02:09:50,840
OF INDIVIDUALS WITH A VARIETY OF

3045
02:09:50,840 --> 02:09:52,520
MENTAL ILLNESSES SO THERE'S MUCH

3046
02:09:52,520 --> 02:09:54,840
TO BE LEARNED FROM THE DATA THAT

3047
02:09:54,840 --> 02:09:56,240
AWFUL US HAS ALREADY RELEASED

3048
02:09:56,240 --> 02:09:57,680
AND THE DATA THAT WILL CONTINUE

3049
02:09:57,680 --> 02:09:59,360
TO BE RELEASED IN THE FUTURE AND

3050
02:09:59,360 --> 02:10:01,120
FOR THOSE OF YOU WHO ARE

3051
02:10:01,120 --> 02:10:03,520
PERSONALLY INTERESTED IN

3052
02:10:03,520 --> 02:10:04,560
PARTICIPATING IN ENROLLMENT

3053
02:10:04,560 --> 02:10:06,280
CONTINUES IT'S EASY AND YOU CAN

3054
02:10:06,280 --> 02:10:10,640
GO ON-LINE AND YOU CAN GO TO ONE

3055
02:10:10,640 --> 02:10:14,480
OF THEIR MANY PHYSICAL EXAM AND

3056
02:10:14,480 --> 02:10:16,080
SAMPLE SELECTION SITES ACROSS

3057
02:10:16,080 --> 02:10:17,080
THE UNITED STATES AND DONATE A

3058
02:10:17,080 --> 02:10:20,080
LITTLE BIT OF BLOOD AND GET

3059
02:10:20,080 --> 02:10:20,760
YOURSELF MEASURED AND YOU ARE ON

3060
02:10:20,760 --> 02:10:22,040
THE WAY.

3061
02:10:22,040 --> 02:10:24,680
IT'S A GREAT WAY TO CONTRIBUTE

3062
02:10:24,680 --> 02:10:27,080
TO SCIENTIFIC ADVANCEMENT AND

3063
02:10:27,080 --> 02:10:30,040
YOU CAN DONATE YOUR CLINICAL

3064
02:10:30,040 --> 02:10:31,360
RECORDS WITH PRESS OF A FEW

3065
02:10:31,360 --> 02:10:34,920
CLICKS OF YOUR MOUSE AND THE

3066
02:10:34,920 --> 02:10:36,720
RESULTS OF THIS RESEARCH ARE

3067
02:10:36,720 --> 02:10:40,880
SHARED WITH YOU AS A PARTICIPANT

3068
02:10:40,880 --> 02:10:45,400
IN THE PROGRAM.

3069
02:10:45,400 --> 02:10:46,880
ANOTHER INITIATIVE IS THE BRAIN

3070
02:10:46,880 --> 02:10:48,360
INITIATIVE.

3071
02:10:48,360 --> 02:10:49,200
ALMOST HALF OF THE BRAIN

3072
02:10:49,200 --> 02:10:51,760
INITIATIVE BRANCH COME THROUGH

3073
02:10:51,760 --> 02:10:52,120
THE NIH.

3074
02:10:52,120 --> 02:10:54,760
THE NIMH AND IN PARTNERSHIP WITH

3075
02:10:54,760 --> 02:10:56,640
THE NATIONAL INSTITUTE OF

3076
02:10:56,640 --> 02:10:58,040
NEUROLOGICAL DISEASE AND STROKE,

3077
02:10:58,040 --> 02:10:59,840
WE LEAD THE BRAIN INITIATIVE

3078
02:10:59,840 --> 02:11:01,400
WHICH NOW OF COURSE HAS A

3079
02:11:01,400 --> 02:11:04,120
PERMANENT DIRECTOR IN JOHN NAI

3080
02:11:04,120 --> 02:11:10,200
AND DEPUTY DIRECTOR ANDREA

3081
02:11:10,200 --> 02:11:10,560
BECKEL-MITCHNER.

3082
02:11:10,560 --> 02:11:11,680
THEY WILL HOST THE NINTH

3083
02:11:11,680 --> 02:11:12,920
NATIONAL BRAIN INITIATIVE

3084
02:11:12,920 --> 02:11:13,600
MEETING.

3085
02:11:13,600 --> 02:11:17,520
JUST NEXT MONTH.

3086
02:11:17,520 --> 02:11:19,400
IT WILL HAVE IN-PERSON AND

3087
02:11:19,400 --> 02:11:21,000
VIRTUAL COMPONENTS AND IF YOU

3088
02:11:21,000 --> 02:11:23,280
ARE INTERESTED TO SIGN UP AND

3089
02:11:23,280 --> 02:11:25,120
ATTEND HERE IN THE D.C. AREA OR

3090
02:11:25,120 --> 02:11:29,680
IF YOU CAN'T MAKE IT.

3091
02:11:29,680 --> 02:11:30,000
NEXT SLIDE.

3092
02:11:30,000 --> 02:11:31,840
I WANTED TO GIVE YOU AN UPDATE

3093
02:11:31,840 --> 02:11:33,320
ON A PROGRAM THAT WE'RE

3094
02:11:33,320 --> 02:11:35,760
ESPECIALLY PROUD OF, THE

3095
02:11:35,760 --> 02:11:37,440
ACCELERATED MEDICINE PARTNERSHIP

3096
02:11:37,440 --> 02:11:40,160
PROGRAM FOR SCHIZOPHRENIA.

3097
02:11:40,160 --> 02:11:42,200
AS YOU WILL REMEMBER, THOSE OF

3098
02:11:42,200 --> 02:11:43,720
YOU ARE ON COUNCIL AND MANY OF

3099
02:11:43,720 --> 02:11:46,320
YOU IN THE AUDIENCE WHO HAVE

3100
02:11:46,320 --> 02:11:47,520
BEEN WITH US BEFORE.

3101
02:11:47,520 --> 02:11:49,080
THE AMPS SCHIZOPHRENIA PROGRAM

3102
02:11:49,080 --> 02:11:51,360
IS ONE THAT SEEKS TO UNDERSTAND

3103
02:11:51,360 --> 02:11:53,600
WHETHER WE CAN USE BIOMARKERS

3104
02:11:53,600 --> 02:11:55,680
AND FOR TREATMENT DEVELOPMENT

3105
02:11:55,680 --> 02:11:58,800
AND IT WILL HELP BOTH REDUCE

3106
02:11:58,800 --> 02:12:00,200
SYMPTOMS AND PERHAPS PREVENT

3107
02:12:00,200 --> 02:12:03,000
TRANSITION TO PSYCHOSIS IN YOUTH

3108
02:12:03,000 --> 02:12:05,080
AND YOUNG ADULTS AND TEENAGERS

3109
02:12:05,080 --> 02:12:07,520
AT RISK FOR A FIRST EPISODE OF

3110
02:12:07,520 --> 02:12:09,880
PSYCHOSIS AND THIS IS A TRUE

3111
02:12:09,880 --> 02:12:13,360
GLOBAL EFFORT AS YOU CAN SEE BIT

3112
02:12:13,360 --> 02:12:16,560
MANY DIFFERENT SITES DISTRIBUTED

3113
02:12:16,560 --> 02:12:22,960
ACROSS MULTIPLE CONTINENTS AND

3114
02:12:22,960 --> 02:12:24,320
IT SOLVES TWO SEPARATE NETWORKS

3115
02:12:24,320 --> 02:12:25,520
THAT HAVE AGREED, THEY HAVE

3116
02:12:25,520 --> 02:12:27,040
AGREED TO USE THE SAME

3117
02:12:27,040 --> 02:12:31,400
PROTOCOLS, SAME OUTCOME MEASURES

3118
02:12:31,400 --> 02:12:33,920
AND SHARE THEIR DATA TO MAXIMIZE

3119
02:12:33,920 --> 02:12:38,080
OUR ABILITY TO REACH NOT THIS

3120
02:12:38,080 --> 02:12:41,080
IMPORTANT GROUP AND A MILLER

3121
02:12:41,080 --> 02:12:44,160
EIGHT PSYCHOPATHOLOGY AND

3122
02:12:44,160 --> 02:12:45,040
PREVENT 123 WORSING OF THAT TYPE

3123
02:12:45,040 --> 02:12:46,560
OF PATHOLOGY.

3124
02:12:46,560 --> 02:12:47,520
THE PARTNERSHIP IS ONE THAT IS

3125
02:12:47,520 --> 02:12:50,960
RUN BY THE FOUNDATION FOR THE

3126
02:12:50,960 --> 02:12:51,880
NATIONAL INSTITUTE OF HEALTH.

3127
02:12:51,880 --> 02:12:53,520
IT'S A PUBLIC-PRIVATE

3128
02:12:53,520 --> 02:12:55,000
PARTNERSHIP INVOLVING

3129
02:12:55,000 --> 02:12:56,280
PHARMACEUTICAL COMPANIES, NIMH

3130
02:12:56,280 --> 02:12:57,800
AND ADVOCACY ORGANIZATIONS THE

3131
02:12:57,800 --> 02:13:06,280
AND OTHER NON PROFITS AND AND

3132
02:13:06,280 --> 02:13:07,360
WE'RE PROUD WE'VE BEGUN

3133
02:13:07,360 --> 02:13:10,680
ENROLLMENT INTO THESE COHORTS

3134
02:13:10,680 --> 02:13:12,360
AND THEY ARE RAMPING UP AS WE

3135
02:13:12,360 --> 02:13:14,680
SPEAK TO FULL STATUS AND WE HOPE

3136
02:13:14,680 --> 02:13:16,120
TO BE ABLE TO SHARE WITH YOU

3137
02:13:16,120 --> 02:13:18,320
INTERESTING RESULTS FROM THAT AS

3138
02:13:18,320 --> 02:13:22,600
IT BECOMES IN THE COMING YEARS.

3139
02:13:22,600 --> 02:13:23,880
NEXT SLIDE.

3140
02:13:23,880 --> 02:13:28,880
IN JUNE OF 2022 IS WHEN A YEAR

3141
02:13:28,880 --> 02:13:31,280
AGO NOW, RESEARCH STUDY

3142
02:13:31,280 --> 02:13:33,400
PARTICIPANTS IN ENROLLING AND IN

3143
02:13:33,400 --> 02:13:39,560
DECEMBER OF 2022, THE FNIH

3144
02:13:39,560 --> 02:13:40,960
RELEASED A REQUEST FOR

3145
02:13:40,960 --> 02:13:42,120
INFORMATION ON COMPOUNDS THAT

3146
02:13:42,120 --> 02:13:43,720
COULD BE USED IN THE PROOF OF

3147
02:13:43,720 --> 02:13:44,760
PRINCIPLE CLINICAL TRIALS THAT

3148
02:13:44,760 --> 02:13:48,640
COULD BE USED TO TRY TO ASSIST

3149
02:13:48,640 --> 02:13:49,560
INDIVIDUALS IN THESE GROUPS.

3150
02:13:49,560 --> 02:13:53,120
THEY RECEIVED A NUMBER OF

3151
02:13:53,120 --> 02:13:54,400
DIFFERENT POTENTIAL, A NUMBER OF

3152
02:13:54,400 --> 02:13:55,080
DIFFERENT SUGGESTIONS FOR

3153
02:13:55,080 --> 02:13:59,480
POTENTIAL COMPOUNDS TO EVALUATE

3154
02:13:59,480 --> 02:14:01,240
AND THAT WORK IS ON GOING AND WE

3155
02:14:01,240 --> 02:14:03,960
HOPE TO BE ABLE TO BEGIN

3156
02:14:03,960 --> 02:14:05,400
CLINICAL TRIALS IN THIS GROUP IN

3157
02:14:05,400 --> 02:14:06,600
THE NEXT MISS CAL YEAR IN

3158
02:14:06,600 --> 02:14:10,240
FEBRUARY OF 2023, SCHIZOPHRENIA

3159
02:14:10,240 --> 02:14:11,680
DEVELOPERS REPORTED ON THE

3160
02:14:11,680 --> 02:14:13,080
FINALIZATION OF HARMONIZED

3161
02:14:13,080 --> 02:14:14,360
CLINICAL OUTCOME ASSESSMENT USED

3162
02:14:14,360 --> 02:14:17,600
AT THE ALL THE SITES AND THIS

3163
02:14:17,600 --> 02:14:19,640
SPRING WE HOPE TO PUBLISH A

3164
02:14:19,640 --> 02:14:21,160
FUNDING ANNOUNCEMENT ON THOSE

3165
02:14:21,160 --> 02:14:22,880
CLINICAL TRIALS THAT WE'LL HOPE

3166
02:14:22,880 --> 02:14:33,400
TO GIVE IN THE NEXT FISCAL YEAR.

3167
02:14:33,400 --> 02:14:36,160
ANOTHER NIH WIDE INITIATIVE IS

3168
02:14:36,160 --> 02:14:37,680
POSTDOCTORAL FELLOWS AND HOW TO

3169
02:14:37,680 --> 02:14:38,520
SUPPORT BEST.

3170
02:14:38,520 --> 02:14:40,200
THERE'S INCREASING RECOGNITION

3171
02:14:40,200 --> 02:14:46,160
THAT LEVE LEVELS LEVELS OF SUPP,

3172
02:14:46,160 --> 02:14:49,760
FINANCIAL SUPPORT, RESOURCES OR

3173
02:14:49,760 --> 02:14:51,160
BENEFITS ARE INSUFFICIENT TO

3174
02:14:51,160 --> 02:14:52,560
SUPPORT EARLY CAREER SCIENTISTS

3175
02:14:52,560 --> 02:14:55,120
AND ENSURE THEY STAY ENGAGE IN

3176
02:14:55,120 --> 02:14:58,560
THEIR SCIENTIFIC CAREERS AND AS

3177
02:14:58,560 --> 02:15:02,400
A RESULT THE NIH DIRECTOR ASKED

3178
02:15:02,400 --> 02:15:04,200
THE ADVISORY HAD COMMITTEE ON

3179
02:15:04,200 --> 02:15:07,120
REIN-VISIONING NIH SUPPORTED

3180
02:15:07,120 --> 02:15:08,040
POSTDOCTORAL TRAINING AND THIS

3181
02:15:08,040 --> 02:15:09,880
GROUP HAS ISSUED A REQUEST FOR

3182
02:15:09,880 --> 02:15:12,520
INFORMATION WHICH IS NOW CLOSED

3183
02:15:12,520 --> 02:15:15,560
BUT WE'VE RECEIVED THOUSANDS OF

3184
02:15:15,560 --> 02:15:16,880
SUBMISSIONS AND IS CONDUCTING A

3185
02:15:16,880 --> 02:15:18,640
SERIES OF WORKING GROUP

3186
02:15:18,640 --> 02:15:21,760
LISTENING SESSIONS HEARING FROM

3187
02:15:21,760 --> 02:15:25,720
POSTDOCS AND OTHERS ABOUT THE

3188
02:15:25,720 --> 02:15:27,320
ISSUES THEY FACER  AND FROM

3189
02:15:27,320 --> 02:15:27,920
CHILDCARE COMPENSATION ALL THE

3190
02:15:27,920 --> 02:15:30,360
WAY THROUGH TO CAREER PROSPECTS

3191
02:15:30,360 --> 02:15:32,640
AND QUALITY OF LIFE AND WE HOPE

3192
02:15:32,640 --> 02:15:34,240
TO HEAR A REPORT THAT WE CAN

3193
02:15:34,240 --> 02:15:36,440
THEN ADOPT NIH WIDE TO TRY TO

3194
02:15:36,440 --> 02:15:38,760
IMPROVE THE LOT OF OUR

3195
02:15:38,760 --> 02:15:39,800
POSTDOCTORAL WHO DO MUCH OF THE

3196
02:15:39,800 --> 02:15:44,520
WORK THAT YOU ALL APPROVE EACH

3197
02:15:44,520 --> 02:15:48,640
YEAR AND O TO BE FUNDED.

3198
02:15:48,640 --> 02:15:50,280
NEXT SLIDE.

3199
02:15:50,280 --> 02:15:55,240
ANOTHER ISSUE EFFECTING TRAINING

3200
02:15:55,240 --> 02:15:59,600
IS THE PLANNED REVISION OR

3201
02:15:59,600 --> 02:16:02,280
REVIEW OF THE IS CRITERIA FOR

3202
02:16:02,280 --> 02:16:04,560
NATIONAL RESEARCH SERVICE AWARD

3203
02:16:04,560 --> 02:16:08,440
FELLOWSHIPS AND NRSA FELLOWSHIPS

3204
02:16:08,440 --> 02:16:10,200
ARE PRE-DOCTORAL AND

3205
02:16:10,200 --> 02:16:12,440
POSTDOCTORAL AND THE HOPE IS

3206
02:16:12,440 --> 02:16:14,760
THAT IF WE CAN GET THE REVIEW

3207
02:16:14,760 --> 02:16:15,320
CRITERIA CORRECT.

3208
02:16:15,320 --> 02:16:20,960
THAT WE CAN HELP IN THE GOAL OF

3209
02:16:20,960 --> 02:16:26,040
DIVERSIFYING OUR WORKFORCE BASED

3210
02:16:26,040 --> 02:16:28,280
ON MERIT AND NOT OTHER VARIABLES

3211
02:16:28,280 --> 02:16:30,920
I NOTE THE PROPOSED REVIEW

3212
02:16:30,920 --> 02:16:31,520
CRITERIA MODIFICATIONS HERE

3213
02:16:31,520 --> 02:16:33,280
WHICH INCLUDE A FOCUS ON THE

3214
02:16:33,280 --> 02:16:34,440
APPLICATION POTENTIAL AND THE

3215
02:16:34,440 --> 02:16:38,040
STRENGTH AND SCIENCE AND IS A

3216
02:16:38,040 --> 02:16:40,920
BETTER DEFINED CRITERIA AND

3217
02:16:40,920 --> 02:16:42,400
APPLICANTS AND THAT GIVES LESS

3218
02:16:42,400 --> 02:16:46,400
ADVANTAGE APPLICANTS A FAIR

3219
02:16:46,400 --> 02:16:56,880
CHANCE AND ARE AND THE SHOP

3220
02:17:03,040 --> 02:17:03,920
THROUGH THIS REVIEW WE CAN

3221
02:17:03,920 --> 02:17:07,320
IMPROVE OUR ABILITY TO EVALUATE

3222
02:17:07,320 --> 02:17:08,520
FELLOW SHOP APPLICATIONS AND

3223
02:17:08,520 --> 02:17:12,560
MAKE THE PROCESS FAIR.

3224
02:17:12,560 --> 02:17:15,560
WE'RE SEEKING FEEDBACK NOW ON

3225
02:17:15,560 --> 02:17:17,520
THIS REVISION AND SO, I'LL CALL

3226
02:17:17,520 --> 02:17:21,560
YOUR ATTENTION TO THE REQUEST

3227
02:17:21,560 --> 02:17:23,200
FOR INFORMATION THAT CSR PUT OUT

3228
02:17:23,200 --> 02:17:25,240
ON THE PROPOSED CHANGES THAT

3229
02:17:25,240 --> 02:17:28,360
THOSE RESPONSES ARE DO AT THE

3230
02:17:28,360 --> 02:17:29,200
END OF JUNE AND AS WELL AS

3231
02:17:29,200 --> 02:17:30,520
DETAILS ON THE RECOMMENDATIONS

3232
02:17:30,520 --> 02:17:34,160
FOR IMPROVING NRSA FELLOWSHIP

3233
02:17:34,160 --> 02:17:43,960
REVIEW AVAILABLE ON THE WEBSITE.

3234
02:17:43,960 --> 02:17:46,560
I CO-CHAIR THE AWE TIM COMMITTEE

3235
02:17:46,560 --> 02:17:47,520
ON BEHALF OF THE SECRETARY FOR

3236
02:17:47,520 --> 02:17:49,240
HEATH AND HUMAN SERVICE AND WE

3237
02:17:49,240 --> 02:17:54,040
AT NIMH THROUGH THE RESEARCH

3238
02:17:54,040 --> 02:17:55,320
COORDINATION RUN THAT AND

3239
02:17:55,320 --> 02:17:56,240
PROVIDE REPORTS TO CONGRESS AND

3240
02:17:56,240 --> 02:17:57,560
THE PUBLIC ON THE STATE OF

3241
02:17:57,560 --> 02:18:00,960
AFFAIRS FOR AUTISM AS WELL AS A

3242
02:18:00,960 --> 02:18:02,400
STRATEGIC PLAN FOR AUTISM CARE

3243
02:18:02,400 --> 02:18:05,320
AND RESEARCH AND ON APRIL 4th,

3244
02:18:05,320 --> 02:18:06,760
AND INFORMING A RESEARCH AGENDA

3245
02:18:06,760 --> 02:18:11,240
HERE AT NIH, THE IACC HELD A

3246
02:18:11,240 --> 02:18:12,600
VIRTUAL MEETING AND WE DISCUSSED

3247
02:18:12,600 --> 02:18:14,000
UPDATES FROM THE U.S. CENTERS

3248
02:18:14,000 --> 02:18:18,840
FOR DISEASE CONTROL ON AUTISM

3249
02:18:18,840 --> 02:18:20,200
PREVALENCE AS WELL AS DISCUSS

3250
02:18:20,200 --> 02:18:23,400
RACIAL OF ECONOMIC AND AUTISM

3251
02:18:23,400 --> 02:18:25,360
SPECTRUM DISORDER AND HOLD ON TO

3252
02:18:25,360 --> 02:18:26,280
THAT THOUGHT BECAUSE THE SCIENCE

3253
02:18:26,280 --> 02:18:27,720
WILL HIGHLIGHT THOSE IN JUST A

3254
02:18:27,720 --> 02:18:28,640
FEW MOMENTS.

3255
02:18:28,640 --> 02:18:33,040
IN APRIL IN HONOR OF AUTISM

3256
02:18:33,040 --> 02:18:34,160
AWARENESS MONTH.

3257
02:18:34,160 --> 02:18:36,800
THEY HOSTED THE AUTISM SPECIAL

3258
02:18:36,800 --> 02:18:42,600
EVENT SHOWING ARTISTS WHO ARE ON

3259
02:18:42,600 --> 02:18:44,120
THE SPECTRUM AND THEIR WORKS IS

3260
02:18:44,120 --> 02:18:46,720
REALLY A WONDERFUL SHOWCASE AND

3261
02:18:46,720 --> 02:18:50,280
I URGE YOU TO TAKE A LOOK AT THE

3262
02:18:50,280 --> 02:18:51,760
MATERIAL FROM THAT EVENT AND TO

3263
02:18:51,760 --> 02:18:53,520
LOOK AT THE ARTIST WORK WHICH IS

3264
02:18:53,520 --> 02:18:55,000
AVAILABLE OVER THE INTERNET TO

3265
02:18:55,000 --> 02:18:56,840
LOOK AT AND IT'S REALLY

3266
02:18:56,840 --> 02:18:58,680
ASTOUNDING STUFF AND ABSOLUTELY

3267
02:18:58,680 --> 02:19:01,560
BEAUTIFUL AND SPEAKS TO THE

3268
02:19:01,560 --> 02:19:02,360
CREATIVITY OF MANY INDIVIDUALS

3269
02:19:02,360 --> 02:19:06,640
ON THE SPECTRUM AND THEIR

3270
02:19:06,640 --> 02:19:10,680
CAPABILITIES.

3271
02:19:10,680 --> 02:19:12,280
ONE OF THE THINGS WE'RE CHARGED

3272
02:19:12,280 --> 02:19:14,800
WITH AT NIMH AND NIH MORE

3273
02:19:14,800 --> 02:19:17,000
BREEDLY IS ENSURING THAT OUR

3274
02:19:17,000 --> 02:19:20,720
RESEARCH RESULTS IN PUBLIC HEATH

3275
02:19:20,720 --> 02:19:21,120
IMPACT.

3276
02:19:21,120 --> 02:19:22,960
AND AS MANY OF YOU KNOW, THERE

3277
02:19:22,960 --> 02:19:26,240
ARE MEMBERS OF OUR RESEARCH

3278
02:19:26,240 --> 02:19:28,640
FIELD WHO FREQUENTLY SAYS THAT

3279
02:19:28,640 --> 02:19:30,360
RESEARCH AND MENTAL HEALTH HAS

3280
02:19:30,360 --> 02:19:34,400
NOT ACHIEVED PUBLIC-HEALTH

3281
02:19:34,400 --> 02:19:35,640
IMPACT.

3282
02:19:35,640 --> 02:19:37,360
AND WE RECOGNIZE THAT THIS IS

3283
02:19:37,360 --> 02:19:40,520
FALSE AND THAT MUCH OF THE

3284
02:19:40,520 --> 02:19:42,640
INVESTMENTS MADE THROUGH THE NIM

3285
02:19:42,640 --> 02:19:45,000
AND OTHER PLACES HAVE PAID OFF

3286
02:19:45,000 --> 02:19:46,480
TREMENDOUSLY IN TERMS OF

3287
02:19:46,480 --> 02:19:47,080
BENEFITS FOR INDIVIDUALS WITH

3288
02:19:47,080 --> 02:19:49,920
MENTAL ILLNESS AND THEIR

3289
02:19:49,920 --> 02:19:50,720
FAMILIES AND COMMUNITIES.

3290
02:19:50,720 --> 02:19:52,560
IS IT WANTS YOU TO HELP MESSAGE

3291
02:19:52,560 --> 02:19:53,640
THE NOTION THAT RESEARCH NOT

3292
02:19:53,640 --> 02:19:55,600
INVESTMENTS IN THE BIOMEDICAL

3293
02:19:55,600 --> 02:19:57,360
SPACE DO PAYOFF IN TERMS OF

3294
02:19:57,360 --> 02:20:00,040
PUBLIC-HEALTH RESEARCH AND SO

3295
02:20:00,040 --> 02:20:02,040
THEY REVAMPED THEIR WEB PAGE

3296
02:20:02,040 --> 02:20:03,320
THAT DETAIL THE IMPACT OF THE

3297
02:20:03,320 --> 02:20:07,240
NIH RESEARCH AND I'M PROUD TO

3298
02:20:07,240 --> 02:20:10,520
SAY THAT THE EFFORTS TO HELP

3299
02:20:10,520 --> 02:20:12,760
WITH FIRST PSYCHOSIS OR FUTURE

3300
02:20:12,760 --> 02:20:13,800
PROM INNANTLY NOW ON THE WEBSITE

3301
02:20:13,800 --> 02:20:16,720
WITH THE HANDOUT THAT'S

3302
02:20:16,720 --> 02:20:18,800
AVAILABLE AND IS EXPLAINS HOW

3303
02:20:18,800 --> 02:20:22,200
RESEARCH ENCORE DINNATED

3304
02:20:22,200 --> 02:20:28,560
SPECIALTY CARE HAS TRANSFORMED

3305
02:20:28,560 --> 02:20:32,760
THE THIS RESEARCH MILESTONES AND

3306
02:20:32,760 --> 02:20:37,400
SPECIALTY CARE FOR EARL

3307
02:20:37,400 --> 02:20:40,800
SCHIZOPHRENIA I ENCOURAGE YOU TO

3308
02:20:40,800 --> 02:20:42,560
LOOK AT IT AND SHARE IT WITH

3309
02:20:42,560 --> 02:20:43,600
YOUR COLLEAGUES BECAUSE TOO

3310
02:20:43,600 --> 02:20:45,360
OFTEN IN OUR FIELD, WE EMPHASIZE

3311
02:20:45,360 --> 02:20:47,320
WHAT WE DON'T KNOW AND WHAT WE

3312
02:20:47,320 --> 02:20:48,480
HAVEN'T ACCOMPLISHED AND IT'S

3313
02:20:48,480 --> 02:20:49,960
GREAT BECAUSE WE SHOULD BE

3314
02:20:49,960 --> 02:20:53,680
LOOKING FOR WHAT WE CAN DO TO

3315
02:20:53,680 --> 02:20:56,960
HELP PEOPLE SUFFERING FROM

3316
02:20:56,960 --> 02:20:57,920
MENTAL ILLNESS AND WE SHOULD

3317
02:20:57,920 --> 02:21:02,640
LOOK AT WHAT WE HAVEN'T DONE AND

3318
02:21:02,640 --> 02:21:05,040
THE GAPS AND NEEDS AND IF WE

3319
02:21:05,040 --> 02:21:07,360
DON'T PAUSE TO RECOGNIZE WHAT

3320
02:21:07,360 --> 02:21:08,760
RESEARCH HAS ACCOMPLISHED, HOW

3321
02:21:08,760 --> 02:21:10,200
CAN WE ASK CONGRESS FOR DOLLARS

3322
02:21:10,200 --> 02:21:12,600
OF RESEARCH WHICH IN THE END

3323
02:21:12,600 --> 02:21:13,040
DON'T PAYOFF.

3324
02:21:13,040 --> 02:21:14,200
IF WE CAN SHOW THEM WHAT WE'VE

3325
02:21:14,200 --> 02:21:17,240
DONE WITH THE MONEY IN, WHAT THE

3326
02:21:17,240 --> 02:21:18,880
RESEARCH OF ALL OF YOU AND THE

3327
02:21:18,880 --> 02:21:20,160
RESEARCH OF THOUSANDS AND

3328
02:21:20,160 --> 02:21:21,800
THOUSANDS OF PEOPLE AROUND THE

3329
02:21:21,800 --> 02:21:23,280
GLOBE HAVE ACCOMPLISHED IN

3330
02:21:23,280 --> 02:21:27,320
MENTAL HEALTH DELIVERY WE HAVE A

3331
02:21:27,320 --> 02:21:28,720
BETTER CASE FOR ADDRESSING THE

3332
02:21:28,720 --> 02:21:32,000
GAPS AND NEEDS THAT WE ALL

3333
02:21:32,000 --> 02:21:33,440
HIGHLIGHT SO I WANTED TO CALL

3334
02:21:33,440 --> 02:21:37,480
THIS OUT TO YOU AND MAKE SURE

3335
02:21:37,480 --> 02:21:47,840
YOU RECOGNIZE THAT.

3336
02:22:01,400 --> 02:22:06,800
>>NEXT SLIDE.

3337
02:22:06,800 --> 02:22:07,760
IT WAS ANNOUNCED YESTERDAY THE

3338
02:22:07,760 --> 02:22:09,480
WHITE HOUSE INTENDS TO APPOINT

3339
02:22:09,480 --> 02:22:18,240
MONDAYA MONICABERTAGNOLLI THE SO

3340
02:22:18,240 --> 02:22:21,520
PERMANENTLY LEAD THE DIRECTOR OF

3341
02:22:21,520 --> 02:22:23,360
THE NIH AND IF SHE'S CONFIRMED

3342
02:22:23,360 --> 02:22:27,520
BY THE SENATE AND UNTIL THAT,

3343
02:22:27,520 --> 02:22:28,880
SHE WILL REMAIN AS A COLLEAGUE

3344
02:22:28,880 --> 02:22:31,720
OF MINE AND THE DIRECTOR OF THE

3345
02:22:31,720 --> 02:22:33,400
NATIONAL CANCER INSTITUTE AND

3346
02:22:33,400 --> 02:22:36,440
DR. TABAK WILL CONTINUE AS

3347
02:22:36,440 --> 02:22:40,520
ACTING DIRECTOR OF NIH SINCE THE

3348
02:22:40,520 --> 02:22:51,040
INTENTION TO NOMINATE WAS MADE.

3349
02:22:51,480 --> 02:22:54,200
ON MAY SIXTH, A LONGSTANDING

3350
02:22:54,200 --> 02:22:56,520
CONTRIBUTING TO MANY COMPELLING

3351
02:22:56,520 --> 02:22:57,920
POLICIES INCLUDING THOSE ON DATA

3352
02:22:57,920 --> 02:23:02,080
SHARING, CLINICAL TRIALS AND

3353
02:23:02,080 --> 02:23:03,320
OTHER TRIALS STEPPED DOWN FROM

3354
02:23:03,320 --> 02:23:04,880
HER THEN ROLE AS SENIOR ADVISER

3355
02:23:04,880 --> 02:23:06,080
IN THE OFFICE OF THE DIRECTOR

3356
02:23:06,080 --> 02:23:09,120
FOR A LONG TIME SHE SAID THE

3357
02:23:09,120 --> 02:23:10,520
OFFICE OF SCIENCE POLICY IN

3358
02:23:10,520 --> 02:23:12,280
BUILDING ONE AT NIH AND REALLY

3359
02:23:12,280 --> 02:23:13,600
INFLUENCED A LOT OF THE THINGS

3360
02:23:13,600 --> 02:23:15,040
THAT WE TALK A LOT ABOUT

3361
02:23:15,040 --> 02:23:17,760
INCLUDING THE DATA SHARING STUFF

3362
02:23:17,760 --> 02:23:21,440
AND AND MANY OTHER THINGS.

3363
02:23:21,440 --> 02:23:24,080
AND SHE IS MOVING ON TO NEW MASS

3364
02:23:24,080 --> 02:23:27,240
TIMES AND ADVENTURES BUT WE WISH

3365
02:23:27,240 --> 02:23:29,320
HER LUCK.

3366
02:23:29,320 --> 02:23:36,360
IS ON APRIL 24th, KARINA

3367
02:23:36,360 --> 02:23:37,640
WALTERS IS BEGAN SEARCHING AT

3368
02:23:37,640 --> 02:23:39,560
THE TRIBAL HEALTH RESEARCH

3369
02:23:39,560 --> 02:23:41,200
OFFICE AND REPLACING Dr. DAVID

3370
02:23:41,200 --> 02:23:43,720
WILSON WHO IS ASSIGNMENT TO THE

3371
02:23:43,720 --> 02:23:45,400
WHITE HOUSE COUNCIL ON NATIVE

3372
02:23:45,400 --> 02:23:46,720
AMERICAN AFFAIRS AND WE'RE HAPPY

3373
02:23:46,720 --> 02:23:48,720
TO HAVE Dr. WALTERS LEAD THIS

3374
02:23:48,720 --> 02:23:51,000
IMPORTANT OFFICE WHICH HAS MANY

3375
02:23:51,000 --> 02:23:57,000
COLLABORATIONS WITH THE NIMH AND

3376
02:23:57,000 --> 02:23:57,680
SHE'S A MEMBER OF THE CAUCUS

3377
02:23:57,680 --> 02:23:59,440
FOUNDATION OF OKLAHOMA AND SHE

3378
02:23:59,440 --> 02:24:00,720
COMES TO US FROM THE UNIVERSITY

3379
02:24:00,720 --> 02:24:02,240
OF WASHINGTON WHERE HER RESEARCH

3380
02:24:02,240 --> 02:24:05,920
IS 'E IMPECCABLE.

3381
02:24:05,920 --> 02:24:07,640
ANOTHER TRANSITION WE NOTE THAT

3382
02:24:07,640 --> 02:24:10,840
Dr. MARINE GOODNOW

3383
02:24:10,840 --> 02:24:11,680
TRANSITIONED FROM HER ROLE FOR

3384
02:24:11,680 --> 02:24:12,920
AIDS RESEARCH AND DIRECTOR OF

3385
02:24:12,920 --> 02:24:14,680
THE NIH OFFICE OF AIDS RESEARCH

3386
02:24:14,680 --> 02:24:17,360
TO A NEW ROLE AS SENIOR ADVICE

3387
02:24:17,360 --> 02:24:19,080
TORE DR. TABAK IN HIS ACTING

3388
02:24:19,080 --> 02:24:21,720
ROLE AS NIH DIRECTOR.

3389
02:24:21,720 --> 02:24:26,280
SHE WILL BE SUCCEEDED BY IS CAP'

3390
02:24:26,280 --> 02:24:27,240
GIANNIS OF SIDES RESEARCH AND

3391
02:24:27,240 --> 02:24:29,400
I'LL POINT OUT THAT OAR AND THE

3392
02:24:29,400 --> 02:24:31,840
ASSOCIATE DIRECTOR HAVE BEEN

3393
02:24:31,840 --> 02:24:33,200
TREMENDOUSLY SUPPORTIVE OF NIH

3394
02:24:33,200 --> 02:24:34,880
INITIATIVES AND RELATED TO THE

3395
02:24:34,880 --> 02:24:38,840
NEUROSCIENCE AND BEHAVIORAL

3396
02:24:38,840 --> 02:24:42,920
HEALTH IN AIDS AND HIS TREATMENT

3397
02:24:42,920 --> 02:24:47,960
AND WE WILL PUTTING RESOURCES

3398
02:24:47,960 --> 02:24:49,920
AND EFFORT TO OUR WAY RECOGNIZE

3399
02:24:49,920 --> 02:24:51,480
THE IMPORTANCE OF THESE

3400
02:24:51,480 --> 02:24:52,440
BEHAVIORAL APPROACHES TO ENDING

3401
02:24:52,440 --> 02:24:56,480
THE EPIDEMIC.

3402
02:24:56,480 --> 02:25:00,840
NEXT SLIDE.

3403
02:25:00,840 --> 02:25:01,880
ADRIENNE HAW LET STEPPED DOWN

3404
02:25:01,880 --> 02:25:03,280
FOR THE NIH OFFICE OF

3405
02:25:03,280 --> 02:25:06,400
LEGISLATIVE POLICY AND ANALYSIS.

3406
02:25:06,400 --> 02:25:11,120
ADRIAN HAS BEEN A REAL ADVISER

3407
02:25:11,120 --> 02:25:16,200
TO THE LEGISLATIVE ADVISER HERE

3408
02:25:16,200 --> 02:25:19,480
AND HELPING US ACHIEVE OUR GOALS

3409
02:25:19,480 --> 02:25:20,120
WITHIN CONGRESS AND I'VE TOLD

3410
02:25:20,120 --> 02:25:21,760
YOU ABOUT THE WONDERFUL

3411
02:25:21,760 --> 02:25:22,720
INTERACTIONS WE'VE BEEN HAVING

3412
02:25:22,720 --> 02:25:24,320
OVER THE LAST COUPLE OF YEARS

3413
02:25:24,320 --> 02:25:25,920
AND THE MENTAL HEALTH AND I

3414
02:25:25,920 --> 02:25:27,640
THINK THAT IS NO SMALL PART DUE

3415
02:25:27,640 --> 02:25:29,640
TO ADRIAN'S ADVISE OVER THE

3416
02:25:29,640 --> 02:25:31,720
YEARS AND SHE SUCCEEDED BY

3417
02:25:31,720 --> 02:25:34,800
LAWYER INHIGGINS WHO IS SERVING

3418
02:25:34,800 --> 02:25:39,600
WHILE THE SEARCH IS ON GOING.

3419
02:25:39,600 --> 02:25:41,840
SO NOW WE'LL TURN OUR ATTENTION

3420
02:25:41,840 --> 02:25:44,280
TO NIMH AND NEXT SLIDE TO THE

3421
02:25:44,280 --> 02:25:45,680
STRATEGIC PLAN THAT I MENTIONED

3422
02:25:45,680 --> 02:25:46,280
EARLIER.

3423
02:25:46,280 --> 02:25:47,840
SO AS YOU ALL KNOW THE STRATEGIC

3424
02:25:47,840 --> 02:25:49,680
PLAN IS NOW A LIVING DOCUMENT ON

3425
02:25:49,680 --> 02:25:54,440
THE WEB AND WE UPDATED

3426
02:25:54,440 --> 02:25:56,360
FREQUENTLY AND AT LEAST ANNUALLY

3427
02:25:56,360 --> 02:25:58,240
AND I'LL ALSO OUT IN ADDITION TO

3428
02:25:58,240 --> 02:26:00,360
THE UP STATES THERE'S SCIENCE

3429
02:26:00,360 --> 02:26:01,760
HIGHLIGHTS AND LINKS AND YOU CAN

3430
02:26:01,760 --> 02:26:04,120
SEE THE RESEARCH WE SUPPORT AND

3431
02:26:04,120 --> 02:26:05,760
THE RESULTS OF THAT RESEARCH

3432
02:26:05,760 --> 02:26:07,440
LinkedIn TO THE DIFFERENT

3433
02:26:07,440 --> 02:26:10,320
AREAS OF PRIORITY IN THE

3434
02:26:10,320 --> 02:26:11,000
STRATEGIC PLAN.

3435
02:26:11,000 --> 02:26:12,440
I'LL POINT OUT THAT WITH THIS

3436
02:26:12,440 --> 02:26:18,360
NEW UPDATE IN 2023, THERE ARE

3437
02:26:18,360 --> 02:26:18,840
CHANGES.

3438
02:26:18,840 --> 02:26:20,720
WE'RE EMPHASISSING NOT THE

3439
02:26:20,720 --> 02:26:22,440
COMMITMENT TO FUNDING RESEARCH

3440
02:26:22,440 --> 02:26:24,160
AIMED AT REDUCING MENTAL HEALTH

3441
02:26:24,160 --> 02:26:25,400
DISPARITIES AND THIS WAS

3442
02:26:25,400 --> 02:26:28,080
PREVIOUSLY IN THE PLAN AS A

3443
02:26:28,080 --> 02:26:30,720
CROSS PUTTING MEASURE BUT NOW

3444
02:26:30,720 --> 02:26:34,120
ELEMENTS OF THESE AIMS ARE IN

3445
02:26:34,120 --> 02:26:35,280
SEVERAL DIFFERENT GOALS TO NOTE

3446
02:26:35,280 --> 02:26:38,880
THAT THE IMPORTANCE FOR EXAMPLE

3447
02:26:38,880 --> 02:26:41,080
IS INEL CONSIDERING DISPARITIES

3448
02:26:41,080 --> 02:26:44,040
AND EQUITIES AS WE EXAMINE

3449
02:26:44,040 --> 02:26:45,880
MENTAL HEALTH TRAJECTORIES OR

3450
02:26:45,880 --> 02:26:50,920
MENTAL HEALTH SERVICES.

3451
02:26:50,920 --> 02:26:53,440
WE CHANGED THE TITLE OF THE

3452
02:26:53,440 --> 02:26:55,200
FOURTH GOAL SPECIFICALLY FOCUSES

3453
02:26:55,200 --> 02:27:00,080
ON SERVICES AS OPPOSED TO OTHER

3454
02:27:00,080 --> 02:27:01,160
PORT GOAL ALTHOUGH WE HAVE THE

3455
02:27:01,160 --> 02:27:03,200
GAME TO IMPACT PUBLIC MENTAL

3456
02:27:03,200 --> 02:27:05,720
HEALTH AND STRENGTHEN

3457
02:27:05,720 --> 02:27:07,320
PUBLIC-HEALTH AND WE FELT IT WAS

3458
02:27:07,320 --> 02:27:09,880
REALLY EXCLUSIVELY FOCUSED ON

3459
02:27:09,880 --> 02:27:11,000
ADVANCING MEMBER HEALTH AND SO

3460
02:27:11,000 --> 02:27:14,800
WE WANTED TO REFLECT THE NEED

3461
02:27:14,800 --> 02:27:15,480
DISCUSSED THERE UNDER THE

3462
02:27:15,480 --> 02:27:18,120
CONTROL AND WE'VE ALSO UPDATED

3463
02:27:18,120 --> 02:27:20,200
THE DESCRIPTIONS OF EXISTING

3464
02:27:20,200 --> 02:27:22,440
NIMH RESOURCES TO HELP FOSTER

3465
02:27:22,440 --> 02:27:24,000
RESOURCE OF DATA SHARING AND

3466
02:27:24,000 --> 02:27:25,160
EXPANDED ON OUR INTEREST IN

3467
02:27:25,160 --> 02:27:27,240
STUDYING THE IMPACT OF SOCIAL

3468
02:27:27,240 --> 02:27:29,960
DETERMINANTS OF HEALTH AND

3469
02:27:29,960 --> 02:27:35,920
MENTAL ILLNESS TRAJECTORY.

3470
02:27:35,920 --> 02:27:38,760
WE ALSO PUBLISH EACH YEAR A

3471
02:27:38,760 --> 02:27:43,280
STRATEGIC PLAN PROGRESS REPORT

3472
02:27:43,280 --> 02:27:45,240
AND IS IT HIGHLIGHTS INITIATIVES

3473
02:27:45,240 --> 02:27:47,160
FUNDED IN THE PAST YEAR AND HERE

3474
02:27:47,160 --> 02:27:49,240
IN THIS YEAR WE TALK ABOUT THE

3475
02:27:49,240 --> 02:27:52,440
BRAIN INITIATIVE AND

3476
02:27:52,440 --> 02:27:53,200
SCHIZOPHRENIA AND AUTISM

3477
02:27:53,200 --> 02:27:54,560
SCREENING AND SUICIDE RISK IN

3478
02:27:54,560 --> 02:27:57,080
YOUTH AND A NEW APPROACH TO METH

3479
02:27:57,080 --> 02:27:58,440
HEALTH DISPARITY RESEARCH AND

3480
02:27:58,440 --> 02:27:59,440
FACTS AND FIGURES ABOUT GRANTS

3481
02:27:59,440 --> 02:28:03,480
IN THE PREVIOUS YEARS SO IT'S A

3482
02:28:03,480 --> 02:28:06,560
WONDERFUL HANDOUT THAT CAN YOU

3483
02:28:06,560 --> 02:28:07,880
SHARE WITH FOLKS WHO YOU MIGHT

3484
02:28:07,880 --> 02:28:12,320
WANT TO EDUCATE THE ROLE OF NIMH

3485
02:28:12,320 --> 02:28:16,760
IN THE RESEARCH OF THE SYSTEM.

3486
02:28:16,760 --> 02:28:17,920
NEXT SLIDE.

3487
02:28:17,920 --> 02:28:19,560
IS VERY EXCITED AN INITIATIVE

3488
02:28:19,560 --> 02:28:21,680
THAT YOU APPROVED LAST YEAR THAT

3489
02:28:21,680 --> 02:28:26,200
WE CONCEPT CLEARED LAST YEAR IS

3490
02:28:26,200 --> 02:28:28,600
LAUNCHED.

3491
02:28:28,600 --> 02:28:30,280
THIS IS THE IMPACT OF MENTAL

3492
02:28:30,280 --> 02:28:33,040
HEALTH INITIATIVE AS YOU RECALL,

3493
02:28:33,040 --> 02:28:34,800
IS THIS IS TO GATHER VARIOUS

3494
02:28:34,800 --> 02:28:36,480
TYPES OF DATA BUT ESPECIALLY

3495
02:28:36,480 --> 02:28:38,480
DATA ON BEHAVIORAL FUNCTION

3496
02:28:38,480 --> 02:28:42,280
ACROSS MULTIPLE DOMAINS AND TO

3497
02:28:42,280 --> 02:28:43,560
COUPLE THAT WITH CLINICAL

3498
02:28:43,560 --> 02:28:44,320
INFORMATION ABOUT INDIVIDUALS

3499
02:28:44,320 --> 02:28:46,320
AND ASK HOW THAT DATA CAN BE

3500
02:28:46,320 --> 02:28:48,840
USED TO AIMING PROVE CLINICAL

3501
02:28:48,840 --> 02:28:53,120
PREDICTIONS AND TO HELP CLINICAL

3502
02:28:53,120 --> 02:28:55,160
DECISION-MAKING.

3503
02:28:55,160 --> 02:28:57,560
THE IMPACT INITIATIVE WILL

3504
02:28:57,560 --> 02:28:59,600
CREATE A INFORM STRUCTURE IS

3505
02:28:59,600 --> 02:29:01,800
BIAS FREE AND INTEGRATES MULTI

3506
02:29:01,800 --> 02:29:04,440
MOTTAL DATASETS REPRESENTED

3507
02:29:04,440 --> 02:29:06,160
DIVERSE AND AGAINER EYES ABLE

3508
02:29:06,160 --> 02:29:11,080
AND THE FUNDING OPPORTUNITIES

3509
02:29:11,080 --> 02:29:11,960
INCLUDE OPPORTUNITIES FOR

3510
02:29:11,960 --> 02:29:13,280
INDIVIDUAL COHORTS AND FOR A

3511
02:29:13,280 --> 02:29:16,000
DATA COORDINATION CENTER THAT

3512
02:29:16,000 --> 02:29:18,520
WILL ENSURE THAT THESE DIFFERENT

3513
02:29:18,520 --> 02:29:20,480
COHORTS ARE UNITED AND THEY WILL

3514
02:29:20,480 --> 02:29:22,680
USE TO POSSIBLE COMMON OUTCOME

3515
02:29:22,680 --> 02:29:24,480
MEASURES AND COMMON DATA

3516
02:29:24,480 --> 02:29:25,760
STRUCTURES AND APPROXIMATE WE'RE

3517
02:29:25,760 --> 02:29:29,760
VERY, VERY EXCITED ABOUT THIS

3518
02:29:29,760 --> 02:29:39,760
INITIATIVE.

3519
02:29:39,760 --> 02:29:43,400
IS WE WILL EXPAND AND MORE

3520
02:29:43,400 --> 02:29:44,680
RAPIDLY IMPLEMENT THESE AND

3521
02:29:44,680 --> 02:29:47,200
ADDITIONAL FUNDING OPPORTUNITIES

3522
02:29:47,200 --> 02:29:50,920
TO FOLLOW.

3523
02:29:50,920 --> 02:29:53,920
NEXT SLIDE.

3524
02:29:53,920 --> 02:29:56,320
HOA WE'VE BEEN WORKING HARD AS I

3525
02:29:56,320 --> 02:29:57,480
DETAILED TO THIS GROUP WE'VE

3526
02:29:57,480 --> 02:30:01,360
BEEN WORKING HARD TO REMEDY

3527
02:30:01,360 --> 02:30:02,840
FAILURES IN OUR REVIEW SYSTEM

3528
02:30:02,840 --> 02:30:07,240
AND OUR GRAND MAKING SYSTEM TO

3529
02:30:07,240 --> 02:30:10,440
ENSURE EQUITY.

3530
02:30:10,440 --> 02:30:12,680
WE CAN EX PANNED ON OUR PEER

3531
02:30:12,680 --> 02:30:14,920
REVIEW PANEL SO I WILL MAKE A

3532
02:30:14,920 --> 02:30:15,800
NAKED PLEA TO EVERYONE LISTENING

3533
02:30:15,800 --> 02:30:17,360
TO THIS, IF YOU ARE INTERESTED

3534
02:30:17,360 --> 02:30:19,280
IN FUNDING THE BEST MENTAL

3535
02:30:19,280 --> 02:30:20,280
HEALTH RESEARCH WE NEED YOU.

3536
02:30:20,280 --> 02:30:24,120
WE NEED SCIENTISTS TO VOLUNTEER

3537
02:30:24,120 --> 02:30:25,640
AND TO PARTICIPATE ON OUR PEER

3538
02:30:25,640 --> 02:30:27,240
REVIEW PANELS SO YOU CAN APPLY

3539
02:30:27,240 --> 02:30:29,240
TO BE A PEER REVIEWER FOR NIH

3540
02:30:29,240 --> 02:30:33,120
GRANTS AND IT'S A VERY SIMPLE

3541
02:30:33,120 --> 02:30:34,560
APPLICATION AND IT'S A WONDERFUL

3542
02:30:34,560 --> 02:30:36,240
OPPORTUNITY TO VOLUNTEER YOUR

3543
02:30:36,240 --> 02:30:38,280
SERVICE AND IT WILL ENABLE US TO

3544
02:30:38,280 --> 02:30:40,000
BUILD A DATABASE OF REVIEWERS

3545
02:30:40,000 --> 02:30:43,040
AND THEIR EXPERTISE TO ENSURE WE

3546
02:30:43,040 --> 02:30:45,080
KNOW IS OUT THERE ABLE TO REVIEW

3547
02:30:45,080 --> 02:30:46,840
IN DIFFERENT YEARS AND MAKE SURE

3548
02:30:46,840 --> 02:30:50,680
TO MAXIMIZE OUR PEER REVIEW

3549
02:30:50,680 --> 02:30:54,400
PROCESS THROUGH DIVERSITY AND

3550
02:30:54,400 --> 02:30:59,560
INCLUSION.

3551
02:30:59,560 --> 02:31:00,960
IS FINALLY, LAST TWO YEARS, WE

3552
02:31:00,960 --> 02:31:05,160
HAVE AWARDED THE JAMES JACKSON

3553
02:31:05,160 --> 02:31:05,640
MEMORIAL AWARD.

3554
02:31:05,640 --> 02:31:08,640
NAMED IN Dr. OF JAMES JACKSON

3555
02:31:08,640 --> 02:31:09,280
A RENOWNED SOCIAL EYE COL GIFT

3556
02:31:09,280 --> 02:31:11,720
AND MEMBER OF THIS COUNCIL AND

3557
02:31:11,720 --> 02:31:14,680
IS WE WILL AWARD ANOTHER IS

3558
02:31:14,680 --> 02:31:16,200
AWARD THIS YEAR.

3559
02:31:16,200 --> 02:31:17,720
NOMINATIONS ARE DUE SOON.

3560
02:31:17,720 --> 02:31:18,640
MAY 22nd.

3561
02:31:18,640 --> 02:31:21,080
WE SEEK NOMINATIONS FOR

3562
02:31:21,080 --> 02:31:23,480
EXCEPTIONAL INTRAMURAL OR

3563
02:31:23,480 --> 02:31:25,200
EXTRAMURAL MENTAL HEALTH

3564
02:31:25,200 --> 02:31:26,360
DISPARITIES RESEARCHERS AND YOU

3565
02:31:26,360 --> 02:31:27,520
CAN VISIT OUR WEBSITE TO LEARN

3566
02:31:27,520 --> 02:31:31,920
HOW TO APPLY.

3567
02:31:31,920 --> 02:31:34,320
ON TO STAFF NOW. VERY PLEASED

3568
02:31:34,320 --> 02:31:36,160
TOANCE NO THE APPOINTMENT OF

3569
02:31:36,160 --> 02:31:37,960
Dr. MARY JUNE REWHO HAS BEEN A

3570
02:31:37,960 --> 02:31:40,360
PROGRAM OFFICER AT THE NIMH

3571
02:31:40,360 --> 02:31:42,400
DIVISION OF RESEARCH AS THE

3572
02:31:42,400 --> 02:31:44,000
ASSOCIATE DIRECTOR FOR

3573
02:31:44,000 --> 02:31:46,520
PREVENTION AND THIS IS A

3574
02:31:46,520 --> 02:31:49,640
CONGRESS LEHMAN DATED POSITION

3575
02:31:49,640 --> 02:31:51,600
AND IT'S A POSITION 245 HAS BEEN

3576
02:31:51,600 --> 02:31:55,160
AN IMPORTANT ONE FOR US AS WE

3577
02:31:55,160 --> 02:31:56,080
SEEK TO DEVELOP BETTER

3578
02:31:56,080 --> 02:31:57,120
APPROACHES TO UNDERSTANDING HOW

3579
02:31:57,120 --> 02:31:59,320
TO PREVENT MENTAL ILLNESSES AS

3580
02:31:59,320 --> 02:32:02,560
OPPOSED TO TREATING THEM AND

3581
02:32:02,560 --> 02:32:04,080
MUCH OF OUR WORK HAS BEEN

3582
02:32:04,080 --> 02:32:05,480
ADVANCED IN THIS AREA BECAUSE OF

3583
02:32:05,480 --> 02:32:10,080
DIRECTORS INCLUDING EVE RIDER

3584
02:32:10,080 --> 02:32:13,040
WHO DID AN OUTSTANDING JOB.

3585
02:32:13,040 --> 02:32:14,560
Dr. RUDY WILL BE OUR

3586
02:32:14,560 --> 02:32:19,120
REPRESENTATIVE TO NIH OFFICE OF

3587
02:32:19,120 --> 02:32:20,040
DISEASE PREVENTION AS WELL AS

3588
02:32:20,040 --> 02:32:23,240
OTHER VARIOUS OTHER COMMITTEES

3589
02:32:23,240 --> 02:32:24,960
ON WHICH NIH GETS TO WORK IN

3590
02:32:24,960 --> 02:32:28,920
PREVENTION INITIATIVES.

3591
02:32:28,920 --> 02:32:31,360
IS Dr. KAREN BURR MAN CHIEF OF

3592
02:32:31,360 --> 02:32:33,800
THE CLINICAL AND TRANSLATIONAL

3593
02:32:33,800 --> 02:32:36,440
NURSE SCIENCE BRANCH AND NEURO

3594
02:32:36,440 --> 02:32:38,160
IMAGES AND PSYCHOSIS STUDY

3595
02:32:38,160 --> 02:32:40,240
SECTION IN OUR INTRAMURAL

3596
02:32:40,240 --> 02:32:41,960
RESEARCH PROGRAM HAS OVER HER

3597
02:32:41,960 --> 02:32:44,600
CAREER ACHIEVED ACCOLADES

3598
02:32:44,600 --> 02:32:45,960
INCONCLUDING OF COURSE, THE

3599
02:32:45,960 --> 02:32:47,200
NATIONAL ACADEMY OF MEDICINE AND

3600
02:32:47,200 --> 02:32:49,560
SHE WAS A FELLOW OF THE AMONG

3601
02:32:49,560 --> 02:32:52,680
ASSOCIATION ADVANCE OF THE

3602
02:32:52,680 --> 02:32:56,040
SCIENCE CONGRATULATIONS TO HER.

3603
02:32:56,040 --> 02:32:57,120
AND OPPORTUNITIES ALL GOOD NEWS.

3604
02:32:57,120 --> 02:32:59,760
WE'RE SAD TO ANNOUNCE THE

3605
02:32:59,760 --> 02:33:01,040
PASSION OF TWO REALLY STALWARTS

3606
02:33:01,040 --> 02:33:06,480
OF OUR INTRAMURAL PROGRAM IN

3607
02:33:06,480 --> 02:33:07,440
APRIL LAST MONTH.

3608
02:33:07,440 --> 02:33:15,160
Dr. BARRIE KAPLAN AND Dr.

3609
02:33:15,160 --> 02:33:18,840
EDITHA NOTTELMANN.

3610
02:33:18,840 --> 02:33:25,800
THEIR PRESENCE WILL BE MISSED.

3611
02:33:25,800 --> 02:33:28,880
LET'S TURN OUR ATTENTION TO SOME

3612
02:33:28,880 --> 02:33:30,520
SCIENCE AND AS ALWAYS I WANT TO

3613
02:33:30,520 --> 02:33:32,120
THANK THE MANY CONTRIBUTIONS

3614
02:33:32,120 --> 02:33:34,040
THAT WERE SUGGESTED FOR

3615
02:33:34,040 --> 02:33:39,680
HIGHLIGHTING HERE BY OUR PROGRAM

3616
02:33:39,680 --> 02:33:40,840
STAFF AND OUR COLLEAGUE.

3617
02:33:40,840 --> 02:33:42,520
I ONLY HAVE TIME FOR TWO OF THEM

3618
02:33:42,520 --> 02:33:43,760
TODAY SO I'LL TURN OUR ATTENTION

3619
02:33:43,760 --> 02:33:45,920
TO EACH OF THOSE IN BETWEEN AND

3620
02:33:45,920 --> 02:33:48,080
THEY DO COVER THE BREADTH OF

3621
02:33:48,080 --> 02:33:50,560
RESEARCH THAT WE HAVE HERE AT

3622
02:33:50,560 --> 02:33:52,760
LEAST FROM MOLECULAR TO SERVICES

3623
02:33:52,760 --> 02:33:53,440
NEXT SLIDE.

3624
02:33:53,440 --> 02:33:55,200
THE FIRST ONE IS IN THE

3625
02:33:55,200 --> 02:33:59,680
NEUROSCIENCE DOMAIN AND THE IS

3626
02:33:59,680 --> 02:34:01,960
TITLE MIGHT CONFUSE YOU AND

3627
02:34:01,960 --> 02:34:04,720
FRANKLY THE ARTICLE CONFUSED ME

3628
02:34:04,720 --> 02:34:06,440
UNTIL I DOUG INTO IT.

3629
02:34:06,440 --> 02:34:09,080
THIS IS WORK THAT COMES OUT OF

3630
02:34:09,080 --> 02:34:09,760
REALLY COLLABORATION BETWEEN

3631
02:34:09,760 --> 02:34:11,720
DAVID ANDERSON AND ANN KENNEDY

3632
02:34:11,720 --> 02:34:15,480
AND IT WAS CARRIED OUT BY A

3633
02:34:15,480 --> 02:34:17,520
NUMBER OF INVESTIGATORS AND

3634
02:34:17,520 --> 02:34:19,760
THESE ARE FOLKS WHO HAVE GONE

3635
02:34:19,760 --> 02:34:22,560
BRAIN INITIATIVE FUNDING AND

3636
02:34:22,560 --> 02:34:24,520
NIMH FUNDING AND THIS RESEARCH

3637
02:34:24,520 --> 02:34:25,560
IS STUDYING AN IMPORTANT PROBLEM

3638
02:34:25,560 --> 02:34:27,120
FOR US TO ADDRESS WHICH IS

3639
02:34:27,120 --> 02:34:29,160
AGGRESSION IN THE COP TEXT OF

3640
02:34:29,160 --> 02:34:33,680
MENTAL  ILLNESS AND IT'S OF IS

3641
02:34:33,680 --> 02:34:35,320
CONCERN IN TERMS OF INDIVIDUALS

3642
02:34:35,320 --> 02:34:37,520
WHO HAVE BEEN THE VICTIM OF

3643
02:34:37,520 --> 02:34:39,240
VIOLENCE OR NOT VICTIMS BY

3644
02:34:39,240 --> 02:34:40,840
VIRTUE OF THEIR ILLNESS CARRY

3645
02:34:40,840 --> 02:34:42,720
OUT VIOLENT ACTS AND SO IT'S

3646
02:34:42,720 --> 02:34:44,480
IMPORTANT THAT WE UNDERSTAND THE

3647
02:34:44,480 --> 02:34:45,760
NEUROBIOLOGY UNDERLYING

3648
02:34:45,760 --> 02:34:46,840
AGGRESSIVE BEHAVIOR AS MANY OF

3649
02:34:46,840 --> 02:34:49,520
YOU KNOW, WE HAVE FORMULATED

3650
02:34:49,520 --> 02:34:51,240
NIMH'S APPROACH WHICH LOOKS AT

3651
02:34:51,240 --> 02:34:52,360
THE INTERSECTION OF MENTAL

3652
02:34:52,360 --> 02:34:54,320
ILLNESS AND AGGRESSION AND

3653
02:34:54,320 --> 02:34:55,560
VIOLENCE IN THE FORM OF A NOTICE

3654
02:34:55,560 --> 02:35:00,960
TO OUR INVESTIGATORS AND WE FEEL

3655
02:35:00,960 --> 02:35:02,680
IT ADHERES TO THE PRINCIPLES

3656
02:35:02,680 --> 02:35:05,400
IDENTIFIED IN THAT NOTICE.

3657
02:35:05,400 --> 02:35:07,400
ALTHOUGH WE'RE LOOKING AT

3658
02:35:07,400 --> 02:35:08,920
AGGRESSIVE BEHAVIOR THE FOCUS IS

3659
02:35:08,920 --> 02:35:11,800
A WAY TO ANALYZE NEURO DATA AND

3660
02:35:11,800 --> 02:35:16,200
TO UNDERSTAND HOW NEURONS DRIVE

3661
02:35:16,200 --> 02:35:17,920
BEHAVIOR SO ALTHOUGH WE THINK

3662
02:35:17,920 --> 02:35:18,880
IT'S SOMETHING WE WANT TO

3663
02:35:18,880 --> 02:35:20,720
UNDERSTAND IN TERMS OF BEHAVIOR,

3664
02:35:20,720 --> 02:35:21,680
AGGRESSION FOR THE PURPOSE OF

3665
02:35:21,680 --> 02:35:25,120
THIS PAPER, IS JUST A BEHAVIOR.

3666
02:35:25,120 --> 02:35:29,560
WE HAVE TO BE TALKING ABOUT IT

3667
02:35:29,560 --> 02:35:30,360
RATIONALLY.

3668
02:35:30,360 --> 02:35:34,400
THE MOTIVATION FOR THIS WORK

3669
02:35:34,400 --> 02:35:35,400
COMES FROM EARLY RESULTS FROM

3670
02:35:35,400 --> 02:35:37,400
LABS INCLUDING THE LABS THAT

3671
02:35:37,400 --> 02:35:38,800
COLLABORATE ON THIS GROUP THAT

3672
02:35:38,800 --> 02:35:41,000
SHOW A CERTAIN SUBSET OF NEURONS

3673
02:35:41,000 --> 02:35:48,280
IN A STRUCTURE DEEP WITHIN OUR

3674
02:35:48,280 --> 02:35:54,160
BRAIN, NOT I'M PULLING ONE OUT

3675
02:35:54,160 --> 02:35:55,920
FROM A PRIOR ART CALLS NOT THE

3676
02:35:55,920 --> 02:35:58,840
ONE WHERE WE'RE CONCERNED WITH

3677
02:35:58,840 --> 02:36:01,920
HERE, SHOWING IF YOU TAKE A

3678
02:36:01,920 --> 02:36:05,960
MOLECULE THAT IS ABLE TO

3679
02:36:05,960 --> 02:36:08,160
ACTIVATE NEURONS SHOULD YOU

3680
02:36:08,160 --> 02:36:09,440
SHINE LIGHT ON THAT MOLECULE AND

3681
02:36:09,440 --> 02:36:10,800
IT'S EXPRESSED WITHIN THESE

3682
02:36:10,800 --> 02:36:12,200
NEURONS, THIS SUBSET OF NEURONS

3683
02:36:12,200 --> 02:36:16,960
IN THE HYPOTHALIMUS, AND YOU

3684
02:36:16,960 --> 02:36:18,320
SHINE LIGHT ON THOSE NEURONS,

3685
02:36:18,320 --> 02:36:20,400
YOU CAN GET DIFFERENT BEHAVIORS

3686
02:36:20,400 --> 02:36:22,120
OUT OF THE MOUSE WHEN YOU EXCITE

3687
02:36:22,120 --> 02:36:25,800
THOSE NEURONS INCLUDING A

3688
02:36:25,800 --> 02:36:27,280
MOUNTING BEHAVIOR WHICH CAN BE

3689
02:36:27,280 --> 02:36:30,160
SEXUAL OR DOMINANCE, DEPENDING

3690
02:36:30,160 --> 02:36:32,400
WHETHER IT'S TO AN INDIVIDUAL OF

3691
02:36:32,400 --> 02:36:36,400
THE SAME OR OF THE OPPOSITE SEX.

3692
02:36:36,400 --> 02:36:37,960
YOU CAN ALSO GET AN ATTACK

3693
02:36:37,960 --> 02:36:41,000
BEHAVIOR WHICH IS FRANKLY A

3694
02:36:41,000 --> 02:36:43,080
VIOLENT ACT AND OR MIXED

3695
02:36:43,080 --> 02:36:46,840
BEHAVIOR AND YOU WILL SEE THE

3696
02:36:46,840 --> 02:36:48,600
MOUNTING IN GREEN, YELLOW AND

3697
02:36:48,600 --> 02:36:51,640
IT'S AN ATTACK AND THE FREQUENCY

3698
02:36:51,640 --> 02:36:53,440
OF THE ATTACK BEHAVIORS

3699
02:36:53,440 --> 02:36:55,840
INCREASES WITH THE STRENGTHS OF

3700
02:36:55,840 --> 02:36:56,880
ACTIVATION OF THOSE NEURONS

3701
02:36:56,880 --> 02:36:58,440
WITHIN THE OF HYPOTHALIMUS SO

3702
02:36:58,440 --> 02:37:00,840
THIS IS THE OBSERVATION AND THE

3703
02:37:00,840 --> 02:37:01,520
QUESTION IS, OKAY, SO THIS IS

3704
02:37:01,520 --> 02:37:05,360
WHAT HAPPENS WHEN YOU

3705
02:37:05,360 --> 02:37:06,640
ARTIFICIALLY ACTIVATE THIS

3706
02:37:06,640 --> 02:37:08,120
SUBSET OF NEURONS IN THE BRAIN

3707
02:37:08,120 --> 02:37:10,240
REGION IT SUGGESTS THAT THAT

3708
02:37:10,240 --> 02:37:11,760
BRAIN REGION IS IMPORTANT FOR

3709
02:37:11,760 --> 02:37:15,640
NATURAL PATTERNS OF AGGRESSIVE

3710
02:37:15,640 --> 02:37:16,920
BEHAVIOR AND HOW IS IT

3711
02:37:16,920 --> 02:37:17,400
IMPORTANT?

3712
02:37:17,400 --> 02:37:18,440
CAN WE UNDERSTAND HOW IT'S

3713
02:37:18,440 --> 02:37:19,000
IMPORTANT.

3714
02:37:19,000 --> 02:37:22,320
THE NEXT STEP IN NEUROSCIENCE IS

3715
02:37:22,320 --> 02:37:24,280
TO RECORD ACTIVITY FROM THOSE

3716
02:37:24,280 --> 02:37:27,120
NEURONS DURING BEHAVIOR.

3717
02:37:27,120 --> 02:37:28,880
SO THAT'S THE FIRST EXPERIMENT

3718
02:37:28,880 --> 02:37:31,280
DOES IN THIS PAPER AND HERE IS

3719
02:37:31,280 --> 02:37:35,520
A, WHAT LOOKS LIKE A BEWILDERING

3720
02:37:35,520 --> 02:37:37,360
GRAPH BUT IT'S ESSENTIALLY A

3721
02:37:37,360 --> 02:37:39,720
ZEST RECORDING FROM MANY NEURONS

3722
02:37:39,720 --> 02:37:41,360
AND EACH IS A COLUMN IN THIS

3723
02:37:41,360 --> 02:37:42,640
GRAPH FROM TWO DIFFERENT BRAIN

3724
02:37:42,640 --> 02:37:46,600
REGIONS ON THE LEFT SIDE OF THE

3725
02:37:46,600 --> 02:37:50,200
WHITE LINE IS A DAVE BRAIN

3726
02:37:50,200 --> 02:37:54,160
REGION AND THE SECOND IS 9 VEN

3727
02:37:54,160 --> 02:37:55,320
RAL MEDIAL HYPOTHALIMUS AND IT'S

3728
02:37:55,320 --> 02:37:57,480
IS A NEURON AND EACH ROW IS A

3729
02:37:57,480 --> 02:37:58,760
PARTICULAR BEHAVIOR THAT THE

3730
02:37:58,760 --> 02:38:00,440
ANIMAL IS ENGAGE IN AND THE

3731
02:38:00,440 --> 02:38:01,600
BRIGHTNESS OF THE COLOR

3732
02:38:01,600 --> 02:38:03,640
INDICATES WHETHER THE NEURON IS

3733
02:38:03,640 --> 02:38:05,440
ACTIVE OR NOT DURING THAT KIND

3734
02:38:05,440 --> 02:38:09,680
OF BEHAVIOR.

3735
02:38:09,680 --> 02:38:15,920
AND IN ARE I WANT YOU TO FOCUS

3736
02:38:15,920 --> 02:38:17,200
ON THE DIFFERENCES BETWEEN THE

3737
02:38:17,200 --> 02:38:17,960
LEFT AND THE RIGHT SIDE OF THE

3738
02:38:17,960 --> 02:38:18,560
GRAPH.

3739
02:38:18,560 --> 02:38:19,960
THE LEFT SIDE OF THE GRAPH, YOU

3740
02:38:19,960 --> 02:38:22,120
SEE LITTLE BLOCKS OF BRIGHTNESS.

3741
02:38:22,120 --> 02:38:23,160
WHAT DOES IT MEAN?

3742
02:38:23,160 --> 02:38:28,800
IT MEANS THAT FOR THE MOST PART,

3743
02:38:28,800 --> 02:38:32,040
A NEURON IS ACTIVE IN ONE OR A

3744
02:38:32,040 --> 02:38:33,440
HANDFUL OF BEHAVIORS AND NOT

3745
02:38:33,440 --> 02:38:36,400
ACTIVE IN THE OTHER BEHAVIOR AND

3746
02:38:36,400 --> 02:38:38,480
WE CALL IT A FORM OF SELECTIVITY

3747
02:38:38,480 --> 02:38:42,320
AND ONE CAN SAY, THERE'S A

3748
02:38:42,320 --> 02:38:43,720
NEURON THAT IS ACTIVE DURING AND

3749
02:38:43,720 --> 02:38:45,320
MAY BE RESPONSIBLE FOR

3750
02:38:45,320 --> 02:38:46,720
APPROACHED BEHAVIORS OR

3751
02:38:46,720 --> 02:38:48,120
SOMETHING CALLED INTERMISSION

3752
02:38:48,120 --> 02:38:50,320
BEHAVIOR WHICH IS A SEXUAL

3753
02:38:50,320 --> 02:38:50,960
BEHAVIOR IN FEMALES.

3754
02:38:50,960 --> 02:38:52,360
IN MALES, YOU CAN SEE THAT IT

3755
02:38:52,360 --> 02:38:54,480
MIGHT BE APPROACHED OR ATTACK

3756
02:38:54,480 --> 02:38:55,840
SOME OF THE YELLOW SQUARES THAT

3757
02:38:55,840 --> 02:38:57,560
YOU SEE ON THE RIGHT-HAND SIDE

3758
02:38:57,560 --> 02:38:59,400
OF THAT LEFT-HAND BLOCK OF

3759
02:38:59,400 --> 02:39:00,000
ACTIVITIES.

3760
02:39:00,000 --> 02:39:01,360
NOW IF YOU LOOK ON THE RIGHT

3761
02:39:01,360 --> 02:39:04,640
SIDE OF THE WHITE LINE IN THE

3762
02:39:04,640 --> 02:39:05,720
ACTIVITY IT'S A DIFFERENT STORY.

3763
02:39:05,720 --> 02:39:07,640
YOU SEE THAT MOST OF THE NEURONS

3764
02:39:07,640 --> 02:39:10,160
ARE INVOLVED OR ACTIVE DURING

3765
02:39:10,160 --> 02:39:12,320
MANY DIFFERENT BEHAVIORS.

3766
02:39:12,320 --> 02:39:14,520
AND SO WE CALL THIS MIXED

3767
02:39:14,520 --> 02:39:15,520
SELECTION ACTIVITY.

3768
02:39:15,520 --> 02:39:18,160
HOW CAN MIXED SELECTION ACTIVITY

3769
02:39:18,160 --> 02:39:19,880
GIVE YOU A RESULT LIKE WE JUST

3770
02:39:19,880 --> 02:39:21,080
SHOWED YOU BEFORE.

3771
02:39:21,080 --> 02:39:23,200
WHEN YOU ACTIVATE THOSE NEURONS,

3772
02:39:23,200 --> 02:39:26,080
AND YOU ACTIVATE THEM STRONGLY

3773
02:39:26,080 --> 02:39:28,360
ENOUGH YOU GET A SPECIFIC

3774
02:39:28,360 --> 02:39:28,840
BEHAVIOR.

3775
02:39:28,840 --> 02:39:29,400
NEXT SLIDE.

3776
02:39:29,400 --> 02:39:31,000
SO IN ORDER TO LOOK AT THIS,

3777
02:39:31,000 --> 02:39:33,400
THEY LOOKED A LOT THE ACTUAL

3778
02:39:33,400 --> 02:39:35,680
DYNAMIC OR CHANGES IN TIME, IN

3779
02:39:35,680 --> 02:39:36,840
ACTIVITIES IN THESE NEURONS SO

3780
02:39:36,840 --> 02:39:38,440
THEY REPORTED THOSE SAME NEURONS

3781
02:39:38,440 --> 02:39:40,560
AND IT'S THE SAME NEURONS BUT

3782
02:39:40,560 --> 02:39:42,040
NOW WE ANALYZE THEM DIFFERENTLY.

3783
02:39:42,040 --> 02:39:44,080
WE LOOK NOT AT THE ACTIVITY OF A

3784
02:39:44,080 --> 02:39:45,480
INDIVIDUAL NEURON IN CAN I

3785
02:39:45,480 --> 02:39:49,680
BEHAVDIFFERENTBEHAVIOR BUT ALL D

3786
02:39:49,680 --> 02:39:51,080
COLLECTIVELY AND HOW THAT

3787
02:39:51,080 --> 02:39:52,440
DIFFERENT TEE CHANGES FROM

3788
02:39:52,440 --> 02:39:55,880
MILLEY SECOND TO MILL A SECOND.

3789
02:39:55,880 --> 02:39:57,560
SO NOW WE CAN SEE ILLUSTRATED

3790
02:39:57,560 --> 02:40:01,360
EACH NEURON IS NOW A ROW AND THE

3791
02:40:01,360 --> 02:40:02,200
ACTIVITY OF THAT NEURON OVER

3792
02:40:02,200 --> 02:40:04,520
TIME IS ILLUSTRATED IN THE

3793
02:40:04,520 --> 02:40:05,600
BLUE-LINE AND SOME GO UP AND

3794
02:40:05,600 --> 02:40:06,800
DOWN AND OTHERS GO DOWN THERE

3795
02:40:06,800 --> 02:40:14,160
AND UP HERE AND IT IF YOU

3796
02:40:14,160 --> 02:40:16,600
IMAGINE, WE CAN DISPLAY THEIR

3797
02:40:16,600 --> 02:40:17,640
ACTIVITY ALL SIMULTANEOUSLY AND

3798
02:40:17,640 --> 02:40:18,880
WE CAN SAY THAT THE ACTIVITY AND

3799
02:40:18,880 --> 02:40:26,080
THE WHOLE NEURAL POPULATION IS

3800
02:40:26,080 --> 02:40:28,200
CHANGING OVER TIME.

3801
02:40:28,200 --> 02:40:30,960
IT'S MOVING THROUGH A MULTI

3802
02:40:30,960 --> 02:40:32,720
DIMENSIONAL SPACE OVER TIME AND

3803
02:40:32,720 --> 02:40:33,640
THAT'S ILLUSTRATED IN THE RIGHT

3804
02:40:33,640 --> 02:40:35,640
HAND HERE IS A GRAPH, IF YOU

3805
02:40:35,640 --> 02:40:38,160
WILL, OF ALL OF THE NEURONS AS

3806
02:40:38,160 --> 02:40:40,080
IT CHANGES OVER TIME AS THE

3807
02:40:40,080 --> 02:40:41,120
ANIMALS BEHAVE.

3808
02:40:41,120 --> 02:40:43,400
OF COURSE, WE CAN'T SEE IN

3809
02:40:43,400 --> 02:40:46,040
MULTIPLE DIMENSIONS WE CAN ONLY

3810
02:40:46,040 --> 02:40:47,280
SEE IN THREE AND REALLY ONLY

3811
02:40:47,280 --> 02:40:49,440
WELL IN TWO WHEN WE LOOK AT A

3812
02:40:49,440 --> 02:40:51,440
JOURNAL ARTICLE SO WE'LL

3813
02:40:51,440 --> 02:40:53,840
REPRESENT THAT ACTIVITY AS A

3814
02:40:53,840 --> 02:40:55,120
MOVEMENT THROUGH SPACE IN TWO OR

3815
02:40:55,120 --> 02:40:59,040
THREE DIMENSIONS.

3816
02:40:59,040 --> 02:41:01,560
SO HERE IS ONE OF THOSE

3817
02:41:01,560 --> 02:41:04,560
DIMENSIONS ILLUSTRATED AND THEY

3818
02:41:04,560 --> 02:41:07,160
LOOKED FOR A DIMENSION THAT

3819
02:41:07,160 --> 02:41:09,400
CORRELATED WITH THIS ATTACK-LIKE

3820
02:41:09,400 --> 02:41:10,640
BEHAVIOR AND SO THIS IS NOT

3821
02:41:10,640 --> 02:41:12,200
LOOKING AT SUBSETS OF NEURONS

3822
02:41:12,200 --> 02:41:15,120
IT'S LOOKING AT A PARTICULAR WAY

3823
02:41:15,120 --> 02:41:17,320
THE NEURONS CHANGE IN TIME AND

3824
02:41:17,320 --> 02:41:20,160
TO SEE WHETHER ONE OF THOSE WAYS

3825
02:41:20,160 --> 02:41:21,440
CORRESPONDS WITH A THE ATTACK

3826
02:41:21,440 --> 02:41:23,960
AND THIS ONE DIMENSION WHICH HAS

3827
02:41:23,960 --> 02:41:26,960
VERY SLOW DYNAMICS, IT CHANGES

3828
02:41:26,960 --> 02:41:28,440
VERY SLOWLY IS ASSOCIATED WITH

3829
02:41:28,440 --> 02:41:29,960
ATTACK SO YOU CAN SEE THAT

3830
02:41:29,960 --> 02:41:30,800
REPRESENTS IN THE MIDDLE GRAPH

3831
02:41:30,800 --> 02:41:33,120
ON THE Y AXIS AND TIME IS ON THE

3832
02:41:33,120 --> 02:41:34,880
X AXIS AND THE LITTLE BOUTS OF

3833
02:41:34,880 --> 02:41:42,440
ATTACK ARE ELEVA ILLUSTRATED BYE

3834
02:41:42,440 --> 02:41:43,840
RED BAR AND IF THERE'S AN ATTACK

3835
02:41:43,840 --> 02:41:46,920
IT'S HIGH AND IF NOT IT'S LOW.

3836
02:41:46,920 --> 02:41:49,320
WHAT YOU CAN SEE, THIS IS HOW

3837
02:41:49,320 --> 02:41:51,840
QUANTIFY ON THE RIGHT-HAND SIDE

3838
02:41:51,840 --> 02:41:53,560
WHERE YOU SUM UP ATTACKS AND

3839
02:41:53,560 --> 02:41:55,200
OTHER KINDS OF BEHAVIOR YOU CAN

3840
02:41:55,200 --> 02:41:57,280
SEE THAT WHEN THE ANIMALS ENGAGE

3841
02:41:57,280 --> 02:41:59,000
IN ATTACK THIS DIMENSION OF

3842
02:41:59,000 --> 02:42:00,640
ACTIVITIES IS VERY, VERY HIGH

3843
02:42:00,640 --> 02:42:02,840
AND WHEN IT'S ENGAGE IN OTHER

3844
02:42:02,840 --> 02:42:07,160
BEHAVIOR IT'S LOWER.

3845
02:42:07,160 --> 02:42:08,720
NOW, THERE'S ANOTHER WAY TO

3846
02:42:08,720 --> 02:42:09,720
THINK ABOUT THIS.

3847
02:42:09,720 --> 02:42:14,960
WHICH IS TO SAY, THAT YES, IT'S

3848
02:42:14,960 --> 02:42:16,400
ATTRACTIVE TO THE DIMENSIONS BUT

3849
02:42:16,400 --> 02:42:18,400
CAN WE LOOK AT THE SHAPE OF THAT

3850
02:42:18,400 --> 02:42:19,920
TRACK THROUGH DIMENSIONS AND

3851
02:42:19,920 --> 02:42:21,560
ALTHOUGH THERE'S MULTIPLE

3852
02:42:21,560 --> 02:42:22,080
DIFFERENT SHAPES THAT ARE

3853
02:42:22,080 --> 02:42:23,480
POSSIBLE, THERE ARE TWO THAT

3854
02:42:23,480 --> 02:42:25,400
REALLY EXCITE BEHAVIORISTS WHEN

3855
02:42:25,400 --> 02:42:28,680
THEY'RE TRYING TO MAP NEURAL

3856
02:42:28,680 --> 02:42:29,960
ACTIVITY AND THEY'RE CALLED A

3857
02:42:29,960 --> 02:42:30,480
TRACTORS.

3858
02:42:30,480 --> 02:42:31,880
WELL YOU CAN SEE IF YOU LOOK AT

3859
02:42:31,880 --> 02:42:35,440
THE BOTTOM GRAPH HERE THERE ARE

3860
02:42:35,440 --> 02:42:37,920
WAYS THAT NEURAL ACTIVITY WILL

3861
02:42:37,920 --> 02:42:39,480
FLOW OVER TIME SO ONE OF THOSE

3862
02:42:39,480 --> 02:42:41,200
WAYS IS A POINT ATTRACT OR WHERE

3863
02:42:41,200 --> 02:42:43,040
IF YOU IMAGINE THAT SOME TOTAL

3864
02:42:43,040 --> 02:42:45,120
OF NEURAL ACTIVITY IS IN THE

3865
02:42:45,120 --> 02:42:46,400
MULTI DIMENSIONAL SPACE RIGHT

3866
02:42:46,400 --> 02:42:48,360
BUT WHERE IT IS IN THAT MULTI

3867
02:42:48,360 --> 02:42:49,560
DIMENSIONAL SPACE DUE TO THE

3868
02:42:49,560 --> 02:42:51,000
EFFECTS OF WE CAN CALL IT

3869
02:42:51,000 --> 02:42:54,600
GRAVITY, IT'S GOING TO FALL INTO

3870
02:42:54,600 --> 02:42:55,640
THE MIDDLE TO A PARTICULAR POINT

3871
02:42:55,640 --> 02:43:00,040
SO THE WHOLE NEURAL NETWORK IS

3872
02:43:00,040 --> 02:43:02,480
SET UP TO DRIVE TO A SINGLE

3873
02:43:02,480 --> 02:43:04,760
POINT IN STATE SPACE AND A

3874
02:43:04,760 --> 02:43:06,080
SINGLE KIND OF PATTERN OF

3875
02:43:06,080 --> 02:43:07,480
ACTIVITY SO EVERYWHERE YOU ARE

3876
02:43:07,480 --> 02:43:09,400
IN THAT SPACE YOU ARE MOVING TO

3877
02:43:09,400 --> 02:43:10,840
ONE POINT IT'S CALLED A POINT OF

3878
02:43:10,840 --> 02:43:11,520
TRACK.

3879
02:43:11,520 --> 02:43:13,080
THAT'S USEFUL IF YOU WANT TO GET

3880
02:43:13,080 --> 02:43:14,120
SOMEWHERE AND STAY THERE.

3881
02:43:14,120 --> 02:43:16,320
BUT NOT IF YOU WANT TO EVOLVE A

3882
02:43:16,320 --> 02:43:19,200
PATTERN OF ACTIVITY OVER TIME.

3883
02:43:19,200 --> 02:43:21,960
THEN YOU NEED A LINE ATTRACTER.

3884
02:43:21,960 --> 02:43:22,800
WHERE YOU ARE IN THE SPACE YOU

3885
02:43:22,800 --> 02:43:27,240
ARE GOING TO SOME PLACE IN A

3886
02:43:27,240 --> 02:43:28,680
TROUGH THAT TUNNELS YOU ALONG

3887
02:43:28,680 --> 02:43:30,320
THAT TROUGH AND SO THAT YOU

3888
02:43:30,320 --> 02:43:31,880
START OUT WHERE YOU START ON

3889
02:43:31,880 --> 02:43:33,840
THAT LITTLE V-SHAPED THING YOU

3890
02:43:33,840 --> 02:43:35,440
GO FIRST TO THE TROUGH AND THEN

3891
02:43:35,440 --> 02:43:38,200
YOU GO ALONG THE TROUGH AND WHAT

3892
02:43:38,200 --> 02:43:41,040
THAT WOULD DO IS CAUSE THE

3893
02:43:41,040 --> 02:43:44,720
NEURONS TO FORM A CHANNEL OR

3894
02:43:44,720 --> 02:43:46,280
PATTERN OF ACTIVITY THAT GOES

3895
02:43:46,280 --> 02:43:48,120
ALONG A PATTERN TO EVOKE A

3896
02:43:48,120 --> 02:43:49,960
SERIES OF BEHAVIORS.

3897
02:43:49,960 --> 02:44:00,520
AND THAT IS WHAT HAPPENS IN THE

3898
02:44:04,200 --> 02:44:06,320
SAME TEST AND YOU CAN SEE THAT

3899
02:44:06,320 --> 02:44:07,800
ACTIVITIES STARTS FAR AWAY FROM

3900
02:44:07,800 --> 02:44:10,560
THE DOTTED LINE WHICH IS LIKE

3901
02:44:10,560 --> 02:44:12,200
THAT TRAM IN A LINEAR A TRACK

3902
02:44:12,200 --> 02:44:13,120
TER AND IT MOVES TOWARDS THE

3903
02:44:13,120 --> 02:44:17,760
LINE AND THEN MOVES ALONG THE

3904
02:44:17,760 --> 02:44:19,160
LINE AS THE ATTACK CONTINUES.

3905
02:44:19,160 --> 02:44:22,240
WHEN IT'S OVER IT GOES OFF THE

3906
02:44:22,240 --> 02:44:23,880
LINE AND OF IT GOES BACK TO THE

3907
02:44:23,880 --> 02:44:25,600
LINE AND MOVES ALONG THE LINE AS

3908
02:44:25,600 --> 02:44:30,440
THE ATTACK IS NOTED.

3909
02:44:30,440 --> 02:44:32,920
NEXT SLIDE.

3910
02:44:32,920 --> 02:44:35,080
THE STRENGTH, THE DEGREE TO

3911
02:44:35,080 --> 02:44:38,480
WHICH THE NEURONS ARE FORCED

3912
02:44:38,480 --> 02:44:40,560
INTO THIS LINE, IS RELATED TO

3913
02:44:40,560 --> 02:44:43,080
THE DEGREE TO WHICH THE MOUSE

3914
02:44:43,080 --> 02:44:44,880
SPENDS TIME ATTACKING SO THE

3915
02:44:44,880 --> 02:44:48,120
STRENGTH OF THIS LINEAR A TRACK

3916
02:44:48,120 --> 02:44:53,840
TER DETERMINES HOW MUCH ATTACK

3917
02:44:53,840 --> 02:44:54,920
THE MOUSE IS ENGAGE IN.

3918
02:44:54,920 --> 02:44:57,480
IT'S PART OF OF A LONG LINE OF

3919
02:44:57,480 --> 02:44:58,800
RECOGNIZE THE IMPORTANCE OF

3920
02:44:58,800 --> 02:45:01,120
NUMBER ONE OF MULTIPLE O

3921
02:45:01,120 --> 02:45:02,520
MULTIPLE NEURONS COOPERATE TO GO

3922
02:45:02,520 --> 02:45:06,600
DO A BEHAVIOR AND WE LEARNED

3923
02:45:06,600 --> 02:45:08,000
THROUGH THE BRAIN INITIATIVE WE

3924
02:45:08,000 --> 02:45:09,840
CAN'T JUST STUDY A SINGLE NEURON

3925
02:45:09,840 --> 02:45:11,560
OR A SMALL GROUP OF NEURONS WE

3926
02:45:11,560 --> 02:45:13,240
HAVE TO STUDY PATTERNS ACROSS

3927
02:45:13,240 --> 02:45:16,640
MULTIPLE NEURONS AND NUMBER TWO,

3928
02:45:16,640 --> 02:45:17,560
IT IND INDICATES THE IMPORTANCE

3929
02:45:17,560 --> 02:45:20,080
OF CHANGES OVER TIME IN A NEURAL

3930
02:45:20,080 --> 02:45:21,480
SYSTEM AND WE CAN'T CONCERN

3931
02:45:21,480 --> 02:45:22,520
OURSELVES JUST WITH LOOKING AT

3932
02:45:22,520 --> 02:45:29,120
WINDOWS AND TIME, JUST LIKE WE

3933
02:45:29,120 --> 02:45:31,680
HAVE TO LEARN HOW THOUGH UNFOLD

3934
02:45:31,680 --> 02:45:34,160
OVER TIME AND BEHAVIOR AND

3935
02:45:34,160 --> 02:45:39,720
NUMBER THREE THAT WE CAN LEARN

3936
02:45:39,720 --> 02:45:41,000
DETAILS CAUSE PSYCHIATRIC

3937
02:45:41,000 --> 02:45:44,040
RELATIVE BEHAVIORS DOING THESE

3938
02:45:44,040 --> 02:45:45,080
COMPUTATION ALANAL SIS AND NOW

3939
02:45:45,080 --> 02:45:47,520
WE IMAGINE, WELL, LET'S JUST

3940
02:45:47,520 --> 02:45:49,280
SHUT OFF ACTIVITY WE MIGHT BE

3941
02:45:49,280 --> 02:45:51,080
ABLE TO HELP PEOPLE WHO HAVE

3942
02:45:51,080 --> 02:45:54,760
PROBLEMS WITH AGGRESSION AND

3943
02:45:54,760 --> 02:45:58,520
LET'S SAY SEVERE DISORDER WHO

3944
02:45:58,520 --> 02:46:00,360
ACTS OUT VIOLENTLY AND HERE WE

3945
02:46:00,360 --> 02:46:02,440
LEARN OF COURSE, WE KNOW THAT

3946
02:46:02,440 --> 02:46:04,400
THE HYPO THAT WILL MISS IS

3947
02:46:04,400 --> 02:46:05,560
IMPORTANT FOR THINGS THAT ARE

3948
02:46:05,560 --> 02:46:05,920
IMPORTANT.

3949
02:46:05,920 --> 02:46:08,120
IF WE DON'T TURN IT OFF WE DON'T

3950
02:46:08,120 --> 02:46:09,680
KNOW WHAT DAMAGE WE WOULD DO BUT

3951
02:46:09,680 --> 02:46:11,000
WE CAN IMAGINE IDENTIFYING

3952
02:46:11,000 --> 02:46:12,400
PERIODS OF TIME DUE TO THE

3953
02:46:12,400 --> 02:46:16,040
DYNAMICS OF THE NEURON WHERE AN

3954
02:46:16,040 --> 02:46:17,040
INDIVIDUAL MIGHT BE SLIPPING

3955
02:46:17,040 --> 02:46:18,880
INTO THIS TROUGH AND DISRUPTING

3956
02:46:18,880 --> 02:46:24,520
THAT TROUGH IN SOME WAY AND IS

3957
02:46:24,520 --> 02:46:25,800
LOTS OF THINGS WE CAN LEARN FROM

3958
02:46:25,800 --> 02:46:27,280
THIS PAPER AND I THOUGHT IT WAS

3959
02:46:27,280 --> 02:46:28,480
WONDERFUL TO HIGHLIGHT AND I

3960
02:46:28,480 --> 02:46:30,240
WANT TO THANK OUR STAFF WHO

3961
02:46:30,240 --> 02:46:35,280
SUGGESTED IT TO ME.

3962
02:46:35,280 --> 02:46:36,800
1 LET'S GO TO THE OTHER END OF

3963
02:46:36,800 --> 02:46:39,520
OUR SPECTRUM OF RESEARCH AND

3964
02:46:39,520 --> 02:46:41,400
LET'S TALK ABOUT AN EFFORT TO

3965
02:46:41,400 --> 02:46:48,160
IMPROVE ACCESS OF CARE AND TO

3966
02:46:48,160 --> 02:46:49,280
INDIVIDUALS AND TODDLERS WITH

3967
02:46:49,280 --> 02:46:50,360
AUTISM IN THEIR FAMILIES.

3968
02:46:50,360 --> 02:46:51,480
THIS IS IMPORTANT.

3969
02:46:51,480 --> 02:46:55,440
FOR SEVERAL DIFFERENT REASONS.

3970
02:46:55,440 --> 02:46:57,440
NUMBER ONE, WE KNOW EARLY ACCESS

3971
02:46:57,440 --> 02:46:58,800
TO CARE FOR INDIVIDUALS WITH

3972
02:46:58,800 --> 02:47:00,440
AUTISM MATTERS AND IT MALTERS

3973
02:47:00,440 --> 02:47:01,600
BECAUSE THEY WILL DO BETTER IN

3974
02:47:01,600 --> 02:47:03,480
THE LONG RUN AND IT MATTERS

3975
02:47:03,480 --> 02:47:04,400
BECAUSE THEY ARE MORE AMENABLE

3976
02:47:04,400 --> 02:47:06,120
TO THERAPY, IT MATTERS BECAUSE

3977
02:47:06,120 --> 02:47:07,680
WE WANT TO TRY TO IDENTIFY AND

3978
02:47:07,680 --> 02:47:08,600
RESCUE LANGUAGE IN PARTICULAR

3979
02:47:08,600 --> 02:47:12,680
BECAUSE LANGUAGE IS AN IMPORTANT

3980
02:47:12,680 --> 02:47:14,480
OUTCOME.

3981
02:47:14,480 --> 02:47:17,120
IT WILL ENSURE SUCCESS IN

3982
02:47:17,120 --> 02:47:18,840
DOMAINS IN LIFE AND THE EARLIER

3983
02:47:18,840 --> 02:47:20,280
WE CAN INTERVENE THE BETTER.

3984
02:47:20,280 --> 02:47:22,240
NUMBER TWO, THERE ARE

3985
02:47:22,240 --> 02:47:23,040
DISPARITIES, FORTUNATELY IN THIS

3986
02:47:23,040 --> 02:47:24,480
COUNTRY NARROWING DISPARITIES

3987
02:47:24,480 --> 02:47:25,320
AND WE'RE LEARNING SOMETHING

3988
02:47:25,320 --> 02:47:29,360
FROM THIS ABOUT WHY PERHAPS BUT

3989
02:47:29,360 --> 02:47:31,240
THERE ARE DISPARITIES THE AGE IN

3990
02:47:31,240 --> 02:47:32,920
WHICH WE DIAGNOSE INDIVIDUALS

3991
02:47:32,920 --> 02:47:35,280
WITH AUTISM AND WE DIAGNOSE THEM

3992
02:47:35,280 --> 02:47:41,760
LATER IN MINORTIZIED INDIVIDUALS

3993
02:47:41,760 --> 02:47:43,600
AND THE OUTCOMES MAY BE WORSE

3994
02:47:43,600 --> 02:47:49,160
AND SO WE NEED BETTER MOLDS TO

3995
02:47:49,160 --> 02:47:50,520
IDENTIFY AND REFER INDIVIDUALS

3996
02:47:50,520 --> 02:47:53,280
WITH AUTISM AND SCREENING MODELS

3997
02:47:53,280 --> 02:47:55,600
BECAUSE O IT CAN BE DIFFICULT TO

3998
02:47:55,600 --> 02:47:56,920
RECOGNIZE AUTISM TODDLERS.

3999
02:47:56,920 --> 02:48:00,680
WE SUPPORT BOTH AT NIMH AND THE

4000
02:48:00,680 --> 02:48:02,560
CENTERS OF EXCELLENCE MOST OTHER

4001
02:48:02,560 --> 02:48:06,600
INSTITUTES AT NIH SUPPORT

4002
02:48:06,600 --> 02:48:08,040
RESEARCH INTO THE MODELS OF

4003
02:48:08,040 --> 02:48:09,280
SCREENING AND ONE OF THEM THAT

4004
02:48:09,280 --> 02:48:11,320
WE SUPPOSE SORT THIS GET SET

4005
02:48:11,320 --> 02:48:17,400
EARLY PROGRAM WHICH INVOLVES A

4006
02:48:17,400 --> 02:48:18,440
DIGITAL APPROACH AS WELL AS

4007
02:48:18,440 --> 02:48:20,160
QUESTIONNAIRES TO THE FAMILY

4008
02:48:20,160 --> 02:48:21,800
MEMBERS AND THEY'RE DONE IN

4009
02:48:21,800 --> 02:48:25,480
PRIMARY CARE SETTINGS AND THIS

4010
02:48:25,480 --> 02:48:27,440
IS A TEST OF THIS PROCESS.

4011
02:48:27,440 --> 02:48:28,640
NUMBER ONE IT'S A TEST TO SEE

4012
02:48:28,640 --> 02:48:30,240
WHETHER IT WORKS AND IT'S A TEST

4013
02:48:30,240 --> 02:48:32,680
TO SEE WHETHER IT WILL REDUCE

4014
02:48:32,680 --> 02:48:34,640
DISPARITIES AND NOT JUST DIS PAR

4015
02:48:34,640 --> 02:48:36,040
TIES IN IDENTIFICATION BUT LATER

4016
02:48:36,040 --> 02:48:40,160
ON DISPARITIES IN ACCESS TO

4017
02:48:40,160 --> 02:48:44,320
CARE.

4018
02:48:44,320 --> 02:48:46,560
SO IT LOOKED AT THOUSANDS OF

4019
02:48:46,560 --> 02:48:47,160
SCREENS IN THE SAN DIEGO AREA

4020
02:48:47,160 --> 02:48:48,760
AND IN A POPULATION THAT

4021
02:48:48,760 --> 02:48:52,480
INCLUDES LARGE NUMBERS OF

4022
02:48:52,480 --> 02:48:55,320
HISPANICS.

4023
02:48:55,320 --> 02:48:58,360
ASKED WERE WHETHER THIS MODEL

4024
02:48:58,360 --> 02:49:02,800
WITH BILINGUAL CAPABILITIES AND

4025
02:49:02,800 --> 02:49:03,520
WILL RESULT IN EARLY

4026
02:49:03,520 --> 02:49:04,640
IDENTIFICATION OF RISK AND

4027
02:49:04,640 --> 02:49:08,160
EARLIER REFERRAL AND DIAGNOSIS

4028
02:49:08,160 --> 02:49:14,120
AND APPROXIMATE BETTER CARE.

4029
02:49:14,120 --> 02:49:16,160
THIS IS A SCHEMATIC OF THE OVER

4030
02:49:16,160 --> 02:49:18,120
ALL PROCESS AND THE ENGLISHES OF

4031
02:49:18,120 --> 02:49:20,000
THE NOT INTERVENTION IN A REAL

4032
02:49:20,000 --> 02:49:22,920
WORLD SETTING SO WE DON'T HAVE A

4033
02:49:22,920 --> 02:49:25,000
CONTROL IN THIS STUDY BECAUSE WE

4034
02:49:25,000 --> 02:49:30,960
ALREADY KNOW THIS WORKS AND THIS

4035
02:49:30,960 --> 02:49:32,480
IS AN IMPLEMENTATION STUDY AND

4036
02:49:32,480 --> 02:49:34,360
IT'S A DISPARITY STUDY.

4037
02:49:34,360 --> 02:49:35,960
WILL IT WORK WELL FOR

4038
02:49:35,960 --> 02:49:36,640
INDIVIDUALS OF DIFFERENT RACIAL

4039
02:49:36,640 --> 02:49:38,400
AND ETHNIC BACKGROUNDS SO THE

4040
02:49:38,400 --> 02:49:43,480
RESULTS OF THIS STUDY ARE

4041
02:49:43,480 --> 02:49:44,840
INTERESTING AND CONCLUSIVE AND

4042
02:49:44,840 --> 02:49:46,480
LESS SO SO FIRST ON THE

4043
02:49:46,480 --> 02:49:47,600
LEFT-HAND SIDE YOU SEE THE

4044
02:49:47,600 --> 02:49:49,440
AVERAGE SCREENING AGE IN THE

4045
02:49:49,440 --> 02:49:51,080
CONTEXT OF THE GET SET EARLY

4046
02:49:51,080 --> 02:49:58,600
MODEL IN REAL WORLD SETTINGS AND

4047
02:49:58,600 --> 02:49:59,800
BROKEN OUT WITH ETHNICITY AND

4048
02:49:59,800 --> 02:50:02,120
RACE AND YOU SEE THE AVERAGE AGE

4049
02:50:02,120 --> 02:50:03,000
AT WHICH TODDLERS ARE SCREENED

4050
02:50:03,000 --> 02:50:05,400
WITH THE GET SET ARTICLE PROGRAM

4051
02:50:05,400 --> 02:50:08,680
AND IT'S BETWEEN 16 AND 17

4052
02:50:08,680 --> 02:50:09,600
MONTHS AND RIGHT GO 17 MONTHS

4053
02:50:09,600 --> 02:50:12,320
AND THAT IT'S MORE OR LESS THE

4054
02:50:12,320 --> 02:50:14,840
SAME FOR DIFFERENT RACES AND ETH

4055
02:50:14,840 --> 02:50:19,280
NICE TEASE AND IF YOU LOOK AT

4056
02:50:19,280 --> 02:50:22,120
THEY WERE SET FOR AN EVALUATION.

4057
02:50:22,120 --> 02:50:23,280
MOST BUN ALL WERE DONE AT THE

4058
02:50:23,280 --> 02:50:24,320
UNIVERSITY OF CALIFORNIA SAN

4059
02:50:24,320 --> 02:50:25,720
DIEGO WHICH OFFERED FREE

4060
02:50:25,720 --> 02:50:26,880
EVALUATIONS AND THE CONTEXT OF

4061
02:50:26,880 --> 02:50:28,680
THE GET SET EARLY MODEL AND

4062
02:50:28,680 --> 02:50:30,400
THERE WERE OTHER COMMUNITY BASED

4063
02:50:30,400 --> 02:50:31,360
PLACES WHERE INDIVIDUALS COULD

4064
02:50:31,360 --> 02:50:37,680
BE EVALUATED AND SO THE AGE AND

4065
02:50:37,680 --> 02:50:38,800
EVALUATION WAS JUST AFTER 20

4066
02:50:38,800 --> 02:50:39,040
MONTHS.

4067
02:50:39,040 --> 02:50:42,680
IT WAS A THREE MONTH DELAY AND I

4068
02:50:42,680 --> 02:50:44,560
DON'T KNOW HOW REALISTIC IT IS

4069
02:50:44,560 --> 02:50:46,040
IN OTHER SETTINGS BUT THIS IS

4070
02:50:46,040 --> 02:50:50,640
WHAT THEY'RE ABLE TO ACHIEVE IN

4071
02:50:50,640 --> 02:50:51,360
SAN DIEGO AND THERE'S VARIANCE

4072
02:50:51,360 --> 02:50:52,880
BASED ON ETHNICITY AND RACE BUT

4073
02:50:52,880 --> 02:50:54,720
IT WAS NOT STATISTICALLY

4074
02:50:54,720 --> 02:50:56,320
SIGNIFICANT EVEN WITH THE LARGE

4075
02:50:56,320 --> 02:50:58,440
NUMBERS OF HISPANIC AND

4076
02:50:58,440 --> 02:50:59,920
NON-HISPANIC AND WITHIN RACES

4077
02:50:59,920 --> 02:51:01,720
YOU SEE THEY'RE VERY SMALL

4078
02:51:01,720 --> 02:51:04,120
NUMBERS OF SCREEN POSITIVE

4079
02:51:04,120 --> 02:51:07,360
INDIVIDUALS WHO ARE AFRICAN

4080
02:51:07,360 --> 02:51:08,760
AMERICAN AND SOME OF THE OTHER

4081
02:51:08,760 --> 02:51:10,160
MINORITY GROUPS BECAUSE THIS IS

4082
02:51:10,160 --> 02:51:16,720
ONE THAT HAS HEAVY HISPANIC

4083
02:51:16,720 --> 02:51:18,320
INCLUSION AND IF YOU LOOK AT THE

4084
02:51:18,320 --> 02:51:20,920
AVERAGE TIME WHICH THOSE WHO

4085
02:51:20,920 --> 02:51:22,440
EVALUATED POSITIVE THAT IS

4086
02:51:22,440 --> 02:51:27,080
RECEIVED A DIAGNOSIS OF AUTISM

4087
02:51:27,080 --> 02:51:37,600
PECK TRUMP DISORDER THAT STARTED

4088
02:51:38,360 --> 02:51:41,440
YOU CAN SEE THE AGE OF ONSET

4089
02:51:41,440 --> 02:51:42,240
DIDN'T DID YOU EVER BETWEEN

4090
02:51:42,240 --> 02:51:45,480
HISPANICS AND NO NON HISPANICS D

4091
02:51:45,480 --> 02:51:48,320
THE QUANTITY WAS LOWER BUT NOT

4092
02:51:48,320 --> 02:51:49,200
SIGNIFICANTLY DIFFERENT IN

4093
02:51:49,200 --> 02:51:50,400
INDIVIDUALS FROM HISPANIC

4094
02:51:50,400 --> 02:51:52,000
COMMUNITIES VERSUS NON-HISPANIC

4095
02:51:52,000 --> 02:51:54,280
COMMUNITIES AND THERE WAS MORE

4096
02:51:54,280 --> 02:51:55,240
VARIANCE BY RACE NEW NOTHING

4097
02:51:55,240 --> 02:51:57,360
SIGNIFICANT BECAUSE OF THE

4098
02:51:57,360 --> 02:51:58,480
SMALLER NUMBERS.

4099
02:51:58,480 --> 02:52:00,560
SO THE AUTHORS ARGUE HERE THE

4100
02:52:00,560 --> 02:52:03,280
EARLY MODEL IN THE CONTEXT OF

4101
02:52:03,280 --> 02:52:03,920
THE SAN DIEGO COMMUNITY CARE

4102
02:52:03,920 --> 02:52:05,640
SYSTEM WHICH IS SOMETHING THAT

4103
02:52:05,640 --> 02:52:10,320
THEY TALK A LOT IN THE PAPER IS

4104
02:52:10,320 --> 02:52:12,120
SUCCESSFULLY ABLE TO ACHIEVE

4105
02:52:12,120 --> 02:52:15,800
EQUITABLE SCREENING AND

4106
02:52:15,800 --> 02:52:16,600
EVALUATION AND TREATMENT WHEN

4107
02:52:16,600 --> 02:52:20,960
IT'S INSTITUTED IN THE CONTEXT

4108
02:52:20,960 --> 02:52:22,400
OF CARE.

4109
02:52:22,400 --> 02:52:23,440
APPROXIMATE ONE OF THE THINGS

4110
02:52:23,440 --> 02:52:26,240
THAT THEY LOOKED AT WAS

4111
02:52:26,240 --> 02:52:31,240
ENGAGEMENT LEVELS ANDEL BY RAISE

4112
02:52:31,240 --> 02:52:39,120
AND ETHNICITY AND THEY FOUND THE

4113
02:52:39,120 --> 02:52:40,360
ENGAGEMENT LEVELS WITH HISPANIC

4114
02:52:40,360 --> 02:52:42,600
AND NON-HISPANIC COMMUNITIES DID

4115
02:52:42,600 --> 02:52:42,920
NOT DIFFER.

4116
02:52:42,920 --> 02:52:44,560
THEY ALSO DIDN'T DIFFER WHITE TO

4117
02:52:44,560 --> 02:52:46,360
MINORITY RACES BUT YOU COULD SEE

4118
02:52:46,360 --> 02:52:47,920
DIFFERENCES THAT JUST WEREN'T

4119
02:52:47,920 --> 02:52:51,800
STATISTIC AND DIG BASED ON THE

4120
02:52:51,800 --> 02:52:53,640
NUMBERS.

4121
02:52:53,640 --> 02:52:55,600
ALL RIGHT, SO THAT IS IT FOR THE

4122
02:52:55,600 --> 02:52:57,640
SCIENCE HIGHLIGHTS AND THE

4123
02:52:57,640 --> 02:53:01,400
CONCLUSIONS OF THIS PAPER ARE

4124
02:53:01,400 --> 02:53:02,240
EQUALLY PROFOUND AND MORE

4125
02:53:02,240 --> 02:53:04,080
DIRECTLY IMPORTANT FOR PUBLIC

4126
02:53:04,080 --> 02:53:05,480
MENTAL HEALTH AND YOU CAN IN

4127
02:53:05,480 --> 02:53:07,800
REAL WORLD SETTINGS INTRODUCE

4128
02:53:07,800 --> 02:53:09,080
UNIVERSAL SCREENING METHODS AND

4129
02:53:09,080 --> 02:53:11,000
PRIMARY CARE SETTINGS AND THEY

4130
02:53:11,000 --> 02:53:13,120
CAN RESULT IN BETTER EQUITY AND

4131
02:53:13,120 --> 02:53:18,920
AT LEAST WITHIN THE HISPANIC

4132
02:53:18,920 --> 02:53:19,800
POPULATION HAD MEMBERS TESTIFY

4133
02:53:19,800 --> 02:53:26,800
DIAGNOSIS AND ACCESS TO CARE.

4134
02:53:26,800 --> 02:53:28,520
APPROXIMATE SO WITH THAT I'LL

4135
02:53:28,520 --> 02:53:31,560
CLOSE WITH ANOTHER MENTION AND

4136
02:53:31,560 --> 02:53:32,960
WE TALKED ABOUT OUR 70

4137
02:53:32,960 --> 02:53:34,080
ANNIVERSARY PROGRAMS.

4138
02:53:34,080 --> 02:53:36,240
NEXT SLIDE.

4139
02:53:36,240 --> 02:53:38,440
SO, NEXT YEAR STARTING IN

4140
02:53:38,440 --> 02:53:39,920
SEPTEMBER 2023, WE WILL

4141
02:53:39,920 --> 02:53:40,840
CELEBRATE 75 YEARS OF

4142
02:53:40,840 --> 02:53:41,880
TRANSFORMING THE UNDERSTANDING

4143
02:53:41,880 --> 02:53:44,720
OF TREATMENT OF MENTAL ILLNESS.

4144
02:53:44,720 --> 02:53:46,120
IT WILL BE A YEAR LONG

4145
02:53:46,120 --> 02:53:49,680
CELEBRATION WITH SYMPOSIUMS,

4146
02:53:49,680 --> 02:53:51,760
LECTURES, SCIENTIFIC MEETINGS

4147
02:53:51,760 --> 02:53:53,080
AND STORIES AND OTHER RESOURCES.

4148
02:53:53,080 --> 02:53:54,600
I WANT TO NOTE THAT ALTHOUGH

4149
02:53:54,600 --> 02:53:56,160
WE'RE CELEBRATING

4150
02:53:56,160 --> 02:53:59,600
ACCOMPLISHMENTS WE'RE NOT

4151
02:53:59,600 --> 02:54:00,240
WHITEWASHING NIMH HISTORY WE'LL

4152
02:54:00,240 --> 02:54:01,720
TALK ABOUT THIS INSTITUTE AND

4153
02:54:01,720 --> 02:54:02,640
WHAT WE HAVE ACCOMPLISHED AND

4154
02:54:02,640 --> 02:54:03,480
WHAT WE HAVE NOT ACCOMPLISHED

4155
02:54:03,480 --> 02:54:05,040
AND WHAT WE NEED TO DO A BETTER

4156
02:54:05,040 --> 02:54:07,280
JOB OF BUT I ENCOURAGE YOU TO

4157
02:54:07,280 --> 02:54:09,400
LOOK AT THE FULL ACTIVITY AND

4158
02:54:09,400 --> 02:54:13,080
RESOURCES THAT WE WILL HAVE NEXT

4159
02:54:13,080 --> 02:54:14,120
SLIDE.

4160
02:54:14,120 --> 02:54:15,560
THE FIRST ONE I WANT TO ANNOUNCE

4161
02:54:15,560 --> 02:54:18,120
IS THE INAUGURAL EVENT THAT WILL

4162
02:54:18,120 --> 02:54:20,720
BE A SYMPOSIUM ON

4163
02:54:20,720 --> 02:54:21,880
SEPTEMBER 13th THAT WILL HAVE

4164
02:54:21,880 --> 02:54:22,920
IN-PERSON AND VIRTUAL OPTIONS

4165
02:54:22,920 --> 02:54:27,840
AND WE'LL EXPLORE KEY SAD

4166
02:54:27,840 --> 02:54:28,880
ADVANCES IN MENTAL HEALTH

4167
02:54:28,880 --> 02:54:31,200
RESEARCH AND SUPPORTED BY NIMH

4168
02:54:31,200 --> 02:54:35,400
AND HEAR VISIONARIES, HYPOTHESIS

4169
02:54:35,400 --> 02:54:37,840
ABOUT WHAT OUR FUTURE MIGHT LOOK

4170
02:54:37,840 --> 02:54:38,320
LIKE.

4171
02:54:38,320 --> 02:54:40,240
SAVE THE DATE.

4172
02:54:40,240 --> 02:54:41,560
THOSE OF YOU THAT CAN ATTEND

4173
02:54:41,560 --> 02:54:42,680
WONDERFUL.

4174
02:54:42,680 --> 02:54:48,360
IF YOU CAN'T, JOIN US VIRTUALLY.

4175
02:54:48,360 --> 02:54:48,960
THAT'S IT.

4176
02:54:48,960 --> 02:54:50,320
I'LL END WITH THIS SLIDE.

4177
02:54:50,320 --> 02:54:53,520
YOU CAN LOOK UP MORE ACTIVITIES

4178
02:54:53,520 --> 02:54:57,040
ON WEBSITE.

4179
02:54:57,040 --> 02:55:00,200
I'LL OPEN IT UP FOR QUESTIONS.

4180
02:55:00,200 --> 02:55:01,480
WE'RE OVER 15 MINUTES.

4181
02:55:01,480 --> 02:55:02,720
BOY.

4182
02:55:02,720 --> 02:55:11,440
I JUST GOT TOO EXCITED.

4183
02:55:11,440 --> 02:55:16,040
>>I THINK MY HAND IS UP
THERE

4184
02:55:16,040 --> 02:55:17,880
FIRST.

4185
02:55:17,880 --> 02:55:25,080
I WOULD LIKE TO COMMENT ON IS

4186
02:55:25,080 --> 02:55:26,800
THE PROGRESS IN TREATMENT OF

4187
02:55:26,800 --> 02:55:28,320
SERIOUS MENTAL ILLNESSES THAT

4188
02:55:28,320 --> 02:55:30,360
HAS OCCURRED IN THE LAST FEW

4189
02:55:30,360 --> 02:55:36,440
YEARS.

4190
02:55:36,440 --> 02:55:41,160
SO, I RECOGNIZE YOU POINTED OUT

4191
02:55:41,160 --> 02:55:45,080
OR ACKNOWLEDGE THAT NIMH GETS A

4192
02:55:45,080 --> 02:55:52,920
LOT OF CRITICISM FROM THE

4193
02:55:52,920 --> 02:55:53,760
CLINICAL AUDIENCE THAT THERE'S

4194
02:55:53,760 --> 02:55:57,320
BEEN NO TREATMENT OVER THE LAST

4195
02:55:57,320 --> 02:56:00,320
SEVERAL DECADES AND AS I WAS

4196
02:56:00,320 --> 02:56:02,800
SITTING HERE, I TOOK A NOTE OF

4197
02:56:02,800 --> 02:56:07,080
NEW ADVANCES.

4198
02:56:07,080 --> 02:56:09,560
SO, OVER THE LAST COUPLE OF

4199
02:56:09,560 --> 02:56:13,440
YEARS, THERE HAVE BEEN SEVERAL

4200
02:56:13,440 --> 02:56:14,480
MEDICATION THAT'S HAVE BEEN

4201
02:56:14,480 --> 02:56:16,200
APPROVED FOR TREATING SERIOUS

4202
02:56:16,200 --> 02:56:17,640
MENTAL ILLNESSES FOR WHICH WE

4203
02:56:17,640 --> 02:56:19,600
HAD NO TREATMENTS BEFORE.

4204
02:56:19,600 --> 02:56:25,400
SO THIS INCLUDES RECENTLY I

4205
02:56:25,400 --> 02:56:32,160
THINK LAST WEEK RICKS PEPPERSOL

4206
02:56:32,160 --> 02:56:34,160
FOR PSYCHOTIC AGITATION.

4207
02:56:34,160 --> 02:56:34,960
THIS IS A BREAK THROUGH IN THE

4208
02:56:34,960 --> 02:56:36,160
TREATMENT OF THIS DISEASE OF THE

4209
02:56:36,160 --> 02:56:37,440
WE HAVE NOTHING THAT IS APPROVED

4210
02:56:37,440 --> 02:56:43,720
FOR TREATING SIGH COT I CAN

4211
02:56:43,720 --> 02:56:43,960
AGITATION.

4212
02:56:43,960 --> 02:56:48,920
IT OCCURS AND EVERY HAS A BLACK

4213
02:56:48,920 --> 02:56:55,520
BOX SAYING SHOULD AND WE NOW

4214
02:56:55,520 --> 02:57:05,920
HAVE NIMH SPENT VAST SUMS OF

4215
02:57:05,920 --> 02:57:07,800
MONEY ON INCLUDING SOME TO MY

4216
02:57:07,800 --> 02:57:11,560
LEFT, YEARS AGO, TRYING TO

4217
02:57:11,560 --> 02:57:14,800
DETERMINE HOW THAT DRUG WORKS.

4218
02:57:14,800 --> 02:57:17,400
ANOTHER BREAK THROUGH MEDICATION

4219
02:57:17,400 --> 02:57:20,520
IS THE MEDICATION

4220
02:57:20,520 --> 02:57:27,920
PEMABANFRIENDSHIPBANFREN TREATMY

4221
02:57:27,920 --> 02:57:29,280
PSYCHOSIS AND IT IS APPROVED

4222
02:57:29,280 --> 02:57:31,240
SPECIFICALLY FOR TREATING

4223
02:57:31,240 --> 02:57:35,880
PSYCHOSIS AND PARKINSON'S

4224
02:57:35,880 --> 02:57:37,360
DISEASE AND IS DEVOID OF ANY

4225
02:57:37,360 --> 02:57:41,080
SIDE EFFECTS AND FOR INDIVIDUALS

4226
02:57:41,080 --> 02:57:45,240
THAT RESPOND TO THIS, IT'S

4227
02:57:45,240 --> 02:57:46,160
TRANSFORMATIVE.

4228
02:57:46,160 --> 02:57:47,200
ANOTHER MEDICATION THAT HAS

4229
02:57:47,200 --> 02:57:52,880
RECENTLY BEEN APPROVED AS IS

4230
02:57:52,880 --> 02:57:53,200
BREXANALONE.

4231
02:57:53,200 --> 02:57:58,440
WE HAD NOTHING FOR POSTPARTUM

4232
02:57:58,440 --> 02:58:00,760
DEPRESSION FOR SERIOUS CASES AND

4233
02:58:00,760 --> 02:58:02,560
FOR ANTI-DIE PRESENTS WHICH

4234
02:58:02,560 --> 02:58:04,000
DON'T WORK VERY WELL AND NOW WE

4235
02:58:04,000 --> 02:58:12,000
KNOW ONE DAY INFUSION,

4236
02:58:12,000 --> 02:58:14,160
BREXANALOE IS TREATING WOMEN WHO

4237
02:58:14,160 --> 02:58:15,680
SUFFER FROM POSTPARTUM AND

4238
02:58:15,680 --> 02:58:16,520
DEPRESSION AND THIS IS

4239
02:58:16,520 --> 02:58:17,760
HIGHLIGHTED IN THE "NEW YORK

4240
02:58:17,760 --> 02:58:20,600
TIMES" OVER THE WEEKEND.

4241
02:58:20,600 --> 02:58:27,000
HIGHLIGHTED WORK FROM FROM UNC D

4242
02:58:27,000 --> 02:58:28,960
THIS IS AN INTERESTING MOLECULE.

4243
02:58:28,960 --> 02:58:31,160
IT'S A MODULATOR OF GAB A

4244
02:58:31,160 --> 02:58:35,200
RECEPTORS AND OF COURSE NIMH IT

4245
02:58:35,200 --> 02:58:36,480
AROSE FROM THE NATIONAL

4246
02:58:36,480 --> 02:58:38,080
INSTITUTE OF MENTAL HEALTH AND

4247
02:58:38,080 --> 02:58:41,040
STEVE PAUL'S LAB MANY YEARS AGO.

4248
02:58:41,040 --> 02:58:43,880
AND THE INSTITUTE HAS FUNDED

4249
02:58:43,880 --> 02:58:47,120
THAT RESEARCH FOR DECADES

4250
02:58:47,120 --> 02:58:48,440
BASICALLY.

4251
02:58:48,440 --> 02:58:53,560
AND THE LAST NEW APPROVAL IS

4252
02:58:53,560 --> 02:58:54,840
ESKATAMINE FOR TREATING

4253
02:58:54,840 --> 02:58:56,800
DEPRESSION, THIS CAME FROM NIMH

4254
02:58:56,800 --> 02:58:59,000
FUNDING RESEARCH AT YALE ABOUT

4255
02:58:59,000 --> 02:58:59,800
20 YEARS AGO.

4256
02:58:59,800 --> 02:59:01,760
SHOWING THAT A SINGLE DOSE OF

4257
02:59:01,760 --> 02:59:03,040
KETAMINE IS EFFECTIVE IN

4258
02:59:03,040 --> 02:59:04,760
TREATING DEPRESSION.

4259
02:59:04,760 --> 02:59:07,680
ALL OF THESE FOUR APPROVED

4260
02:59:07,680 --> 02:59:10,480
MEDICATIONS AND THERE ARE

4261
02:59:10,480 --> 02:59:11,400
SEVERAL MEDICATIONS THAT ARE

4262
02:59:11,400 --> 02:59:13,880
ANTICIPATED TO HAVE APPROVAL

4263
02:59:13,880 --> 02:59:15,080
NEXT YEAR.

4264
02:59:15,080 --> 02:59:17,680
THE FIRST IS THE NOAM A LEAN A

4265
02:59:17,680 --> 02:59:21,120
COMBINATION AND TIE ASPER OWN

4266
02:59:21,120 --> 02:59:23,160
FOR SCHIZOPHRENIA AND THIS HAS

4267
02:59:23,160 --> 02:59:25,560
ALREADY HAD POSITIVE PHASE 3

4268
02:59:25,560 --> 02:59:26,760
CLINICAL TRIALS.

4269
02:59:26,760 --> 02:59:28,480
EXTREMELY ROBUST EFFECT.

4270
02:59:28,480 --> 02:59:31,800
THIS WILL BE THE FIRST NON

4271
02:59:31,800 --> 02:59:34,320
DOPAMINE FOR SCHIZOPHRENIA THAT

4272
02:59:34,320 --> 02:59:35,000
WE'VE HAD.

4273
02:59:35,000 --> 02:59:39,880
AND NIMH FUNDED RESEARCH AND

4274
02:59:39,880 --> 02:59:42,720
SYSTEM PRIMARILY FROM JEFF CON'S

4275
02:59:42,720 --> 02:59:44,560
GROUP I THINK.

4276
02:59:44,560 --> 02:59:46,600
AGAIN, FOR DECADES.

4277
02:59:46,600 --> 02:59:50,560
AND RATIONALE FOR THIS DRUG AND

4278
02:59:50,560 --> 02:59:52,360
PUSHING IT ALONG WOULD NEVER

4279
02:59:52,360 --> 02:59:55,560
HAVE OCCURRED WITHOUT NIMH'S

4280
02:59:55,560 --> 02:59:56,040
SUPPORT.

4281
02:59:56,040 --> 03:00:01,040
AND FINALLY WE HAVE MDMA WHICH

4282
03:00:01,040 --> 03:00:02,640
WILL LIKELY REVOLUTIONIZE THE

4283
03:00:02,640 --> 03:00:04,040
TREATMENT OF POST TRAUMATIC

4284
03:00:04,040 --> 03:00:06,200
STRESS DISORDER AND I'LL GO ON

4285
03:00:06,200 --> 03:00:07,960
THE RECORD TO SAY THAT.

4286
03:00:07,960 --> 03:00:11,120
THERE ARE NOW TWO POSITIVE PHASE

4287
03:00:11,120 --> 03:00:11,720
3 CLINICAL TRIALS.

4288
03:00:11,720 --> 03:00:13,240
ONE WAS REPORTED IN NATURE

4289
03:00:13,240 --> 03:00:14,840
MEDICINE AND THE OTHER HAS NOT

4290
03:00:14,840 --> 03:00:16,360
YET BEEN REPORTED PUBLICLY BUT

4291
03:00:16,360 --> 03:00:18,080
THE RESULTS HAVE BEEN REPORTED

4292
03:00:18,080 --> 03:00:18,560
PUBLICLY.

4293
03:00:18,560 --> 03:00:20,520
THEY'RE GOING TO THE FDA.

4294
03:00:20,520 --> 03:00:24,760
THEY'RE GOING TO THE FDA IN 2024

4295
03:00:24,760 --> 03:00:25,480
FOR APPROVAL.

4296
03:00:25,480 --> 03:00:28,800
THIS WILL TRANSFORM HOW WE TREAT

4297
03:00:28,800 --> 03:00:30,600
PTSD AND WE HAVE SIL SA

4298
03:00:30,600 --> 03:00:31,760
CYBERSECURITY INFOR DEPRESSION

4299
03:00:31,760 --> 03:00:43,080
SASIBEN.I WAS THE ONLY INVESTIGR

4300
03:00:44,840 --> 03:00:48,160
FUNDED TO STUDY PSYCHEDELICS AND

4301
03:00:48,160 --> 03:00:50,440
IT WAS FUNDED THROUGH NIMH.

4302
03:00:50,440 --> 03:00:53,800
MANY YEARS AGO I CAME TO THIS

4303
03:00:53,800 --> 03:00:56,680
MEETING AS A GUEST AND YOU

4304
03:00:56,680 --> 03:00:58,120
HIGHLIGHTED OUR STRUCTURAL WORK

4305
03:00:58,120 --> 03:01:03,320
ON THE LSD PSYCHEDELICS WHICH

4306
03:01:03,320 --> 03:01:04,280
WAS PUBLISHED.

4307
03:01:04,280 --> 03:01:07,160
AT THAT TIME THINK I WAS THE

4308
03:01:07,160 --> 03:01:09,920
ONLY, LITERALLY THE ONLY PERSON

4309
03:01:09,920 --> 03:01:13,400
FUNDED TO STUDY PSYCHEDELICS AND

4310
03:01:13,400 --> 03:01:17,880
FINALLY, THERE'S A BREXANALON

4311
03:01:17,880 --> 03:01:21,400
SHOWING POSITIVE RESULTS FOR

4312
03:01:21,400 --> 03:01:21,960
DEPRESSION.

4313
03:01:21,960 --> 03:01:23,240
SO WE HAVE THESE MEDICATIONS

4314
03:01:23,240 --> 03:01:25,800
THAT REALLY ARE TRANSFORMING HOW

4315
03:01:25,800 --> 03:01:29,920
PSYCHIATRY IS BEING DONE AND YOU

4316
03:01:29,920 --> 03:01:34,320
MIGHT IN YOUR TALKS, YOU MIGHT

4317
03:01:34,320 --> 03:01:37,160
HIGHLIGHT THE IMPORTANCE OF NIMH

4318
03:01:37,160 --> 03:01:39,960
FUNDING ON THE BASIC MECHANISMS

4319
03:01:39,960 --> 03:01:41,760
OF THESE MOLECULES.

4320
03:01:41,760 --> 03:01:45,280
YOU KNOW, IF WE DIDN'T HAVE THIS

4321
03:01:45,280 --> 03:01:47,400
RESEARCH, WE WOULDN'T HAVE A

4322
03:01:47,400 --> 03:01:48,200
CLUE HOW THESE MEDICATIONS

4323
03:01:48,200 --> 03:01:48,800
WORKED.

4324
03:01:48,800 --> 03:01:50,520
PHARMA IS NOT GOING TO FUND THAT

4325
03:01:50,520 --> 03:01:51,240
WORK.

4326
03:01:51,240 --> 03:01:53,840
NOW BECAUSE OF THESE

4327
03:01:53,840 --> 03:01:56,360
ADVANCEMENTS AND THESE SUCCESS

4328
03:01:56,360 --> 03:01:58,520
STORIES, I'M NOW GETTING, I

4329
03:01:58,520 --> 03:02:02,680
WOULDN'T SAY WEEKLY BUT I WOULD

4330
03:02:02,680 --> 03:02:04,320
SAY OCCASIONAL QUERIES FROM

4331
03:02:04,320 --> 03:02:05,720
MAJOR PHARMA, WHO ARE

4332
03:02:05,720 --> 03:02:09,760
CONSIDERING GOING BACK TO THAN

4333
03:02:09,760 --> 03:02:11,160
THIS SPACE.

4334
03:02:11,160 --> 03:02:13,760
AND NIMH CAN TAKE SOME CREDIT

4335
03:02:13,760 --> 03:02:15,600
FOR THAT SO I WOULD SAY IN THE

4336
03:02:15,600 --> 03:02:18,040
FUTURE, DON'T BE SO HARD ON YOUR

4337
03:02:18,040 --> 03:02:18,240
SELF.

4338
03:02:18,240 --> 03:02:20,240
>>IT'S WONDERFUL AS I
MENTIONED

4339
03:02:20,240 --> 03:02:22,440
TO ENSURE THAT WE RECOGNIZE

4340
03:02:22,440 --> 03:02:23,280
SUCCESSES.

4341
03:02:23,280 --> 03:02:25,320
AND ALTHOUGH THE ONE THAT I

4342
03:02:25,320 --> 03:02:26,360
MENTIONED FEATURES THE SUCCESS

4343
03:02:26,360 --> 03:02:28,240
THAT'S REALLY ABOUT THE

4344
03:02:28,240 --> 03:02:29,600
TRANSFORMATION OF SERVICES, YOU

4345
03:02:29,600 --> 03:02:31,120
ARE POINTING OUT SEVERAL

4346
03:02:31,120 --> 03:02:34,480
SUCCESSES IN THE RECENT PAST AND

4347
03:02:34,480 --> 03:02:35,640
SOON-TO-BE FUTURE THAT WHERE WE

4348
03:02:35,640 --> 03:02:37,440
HAVE SOME OF THOSE ADVANCES THAT

4349
03:02:37,440 --> 03:02:39,400
HAVE LED FROM NEUROSCIENCE TO

4350
03:02:39,400 --> 03:02:40,200
DRUG DISCOVERY.

4351
03:02:40,200 --> 03:02:42,920
WE HAVE OTHERS WE CAN CLAIM EVEN

4352
03:02:42,920 --> 03:02:43,760
FURTHER BACK, WE'LL TALK ABOUT

4353
03:02:43,760 --> 03:02:48,160
IT IN THE CONTEXT OF THE

4354
03:02:48,160 --> 03:02:49,560
ANNIVERSARY TO NEUROSCIENCE FROM

4355
03:02:49,560 --> 03:02:50,840
PSYCHE SEW AND SOCIAL

4356
03:02:50,840 --> 03:02:51,360
INTERVENTIONS AS WELL.

4357
03:02:51,360 --> 03:02:52,400
THANK YOU, BRIAN.

4358
03:02:52,400 --> 03:02:53,280
>>MARGARITE AA.

4359
03:02:53,280 --> 03:02:54,520
>>I HAVE A QUICK
QUESTION.

4360
03:02:54,520 --> 03:02:55,800
THANK YOU FOR YOUR PRESENTATION.

4361
03:02:55,800 --> 03:02:57,120
IT WAS INFORMATIVE.

4362
03:02:57,120 --> 03:02:59,200
I KNOW MANY OF US ARE CONCERNED

4363
03:02:59,200 --> 03:03:02,760
THAT WE'RE LOSING DIVERSE TALENT

4364
03:03:02,760 --> 03:03:04,600
BECAUSE OF THE FUNDING LEVELS

4365
03:03:04,600 --> 03:03:05,760
THAT POSTDOCS GET SO I WAS

4366
03:03:05,760 --> 03:03:09,440
REALLY EXCITED TO SEE THAT YOU

4367
03:03:09,440 --> 03:03:10,560
ALL RECEIVED THOUSANDS OF

4368
03:03:10,560 --> 03:03:12,240
RESPONSES TO THE RFI AND I WAS

4369
03:03:12,240 --> 03:03:13,920
JUST WONDERING IF YOU KNOW THE

4370
03:03:13,920 --> 03:03:15,320
TIMELINE FOR THE WORKGROUP IN

4371
03:03:15,320 --> 03:03:16,520
TERMS OF THE WORK THAT THEY'RE

4372
03:03:16,520 --> 03:03:18,040
DOING TO LOOK AT THAT DATA AND

4373
03:03:18,040 --> 03:03:20,080
THEN MAKE RECOMMENDATIONS?

4374
03:03:20,080 --> 03:03:20,600
APPROXIMATE.

4375
03:03:20,600 --> 03:03:23,480
>>I THINK THAT THERE WILL
BE A

4376
03:03:23,480 --> 03:03:24,320
REPORT OUT NEXT MONTH.

4377
03:03:24,320 --> 03:03:27,000
I DON'T KNOW WHETHER THAT WILL

4378
03:03:27,000 --> 03:03:31,480
INCLUDE SPECIFIC RECOMMENDATIONS

4379
03:03:31,480 --> 03:03:35,880
AT THAT TIME.

4380
03:03:35,880 --> 03:03:36,560
>> Joshua Gordon: THERE
ARE NO

4381
03:03:36,560 --> 03:03:37,320
OTHER QUESTIONS OR COMMENTS FROM

4382
03:03:37,320 --> 03:03:39,080
THE COUNCIL, I APPRECIATE YOUR

4383
03:03:39,080 --> 03:03:39,360
FORBEARANCE.

4384
03:03:39,360 --> 03:03:41,560
WE HAVE A PLAN TO RESCUE THE

4385
03:03:41,560 --> 03:03:44,000
CONCLUSION OF THE DAY.

4386
03:03:44,000 --> 03:03:44,840
WE'LL SEE HOW MUCH TIME WE CAN

4387
03:03:44,840 --> 03:03:49,200
MAKE UP IN THE MEANTIME.

4388
03:03:49,200 --> 03:03:51,040
NEXT WE HAVE AN ISSUE BEFORE YOU

4389
03:03:51,040 --> 03:03:56,080
THAT WE ARE SEEKING YOUR ADVICE

4390
03:03:56,080 --> 03:03:56,560
ON.

4391
03:03:56,560 --> 03:03:58,200
IT DOESN'T REQUIRE A VOTE.

4392
03:03:58,200 --> 03:04:00,360
BUT WE WOULD LOVE TO HEAR FROM

4393
03:04:00,360 --> 03:04:01,720
YOU.

4394
03:04:01,720 --> 03:04:03,520
AND FOR OTHERS IN THE COMMUNITY

4395
03:04:03,520 --> 03:04:06,240
AS WE LEARN ABOUT THIS.

4396
03:04:06,240 --> 03:04:07,520
I'M GOING TO PROVIDE AN

4397
03:04:07,520 --> 03:04:08,600
INTRODUCTION AND THEN I'M GOING

4398
03:04:08,600 --> 03:04:15,360
TO TURN IT OVER TO Dr.

4399
03:04:15,360 --> 03:04:17,200
JOHNATHAN PERCENTNER TEAM LEAD

4400
03:04:17,200 --> 03:04:19,840
FOR OUR GENOMICS TEAM IN JUST A

4401
03:04:19,840 --> 03:04:21,400
MOMENT BUT BEFORE I DO THAT, LET

4402
03:04:21,400 --> 03:04:22,760
ME GIVE YOU A LITTLE BIT OF

4403
03:04:22,760 --> 03:04:23,560
BACKGROUND HERE.

4404
03:04:23,560 --> 03:04:25,360
SO AS YOU ALL KNOW, THERE WAS A

4405
03:04:25,360 --> 03:04:29,440
WORKGROUP OF THIS COUNCIL SOME

4406
03:04:29,440 --> 03:04:32,800
YEARS BACK THAT RECOMMENDED THAT

4407
03:04:32,800 --> 03:04:36,000
NIMH REVAMP OUR APPROACH TO

4408
03:04:36,000 --> 03:04:38,360
GENOMICS IN GENERAL AND

4409
03:04:38,360 --> 03:04:40,720
SPECIFICALLY THAT WE ONLY --

4410
03:04:40,720 --> 03:04:42,440
THAT IN ORDER FOR US TO FUND

4411
03:04:42,440 --> 03:04:52,960
RESEARCH NA IS BASED ACHIEVE A

4412
03:04:56,600 --> 03:04:58,960
CERTAIN LEVEL OF STATISTICAL

4413
03:04:58,960 --> 03:04:59,720
CONFIDENCE THAT THAT GENE IS

4414
03:04:59,720 --> 03:05:03,640
LINKED TO THE DISORDER THAT

4415
03:05:03,640 --> 03:05:05,320
PURPORT TO BE STUDYING THROUGH

4416
03:05:05,320 --> 03:05:06,120
THEIR APPLICATION, OTHERWISE WE

4417
03:05:06,120 --> 03:05:09,000
CAN STUDY ANY GENE OR PROTEIN OR

4418
03:05:09,000 --> 03:05:13,680
BIOLOGICAL PROCESS THAT YOU LIKE

4419
03:05:13,680 --> 03:05:15,440
BUT ONLY FROM A SCIENCE

4420
03:05:15,440 --> 03:05:16,920
STANDPOINT AND IT'S LINKED TO A

4421
03:05:16,920 --> 03:05:19,320
IT IS ORDER AND THIS HAS BEEN A

4422
03:05:19,320 --> 03:05:22,280
REALLY IMPORTANT DEVELOPMENT AND

4423
03:05:22,280 --> 03:05:23,200
IT'S A LOT OF THE DECISIONS I

4424
03:05:23,200 --> 03:05:25,200
HAVE MADE AND MY STAFF HAS MADE

4425
03:05:25,200 --> 03:05:26,360
AND YOU HAVE ALL CONFERRED WITH

4426
03:05:26,360 --> 03:05:30,040
OVER THE YEARS AND ONE REFRAIN

4427
03:05:30,040 --> 03:05:32,760
FROM RESEARCHERS WHO HAVE BEEN,

4428
03:05:32,760 --> 03:05:35,400
YOU KNOW, DOWNGRADED IN THEIR

4429
03:05:35,400 --> 03:05:36,480
PRIORITY FROM RESEARCH AND YOU

4430
03:05:36,480 --> 03:05:38,280
DON'T WANT ME STUDYING GENE X,

4431
03:05:38,280 --> 03:05:43,120
WHAT GENE SHOULD I BE STUDYING?

4432
03:05:43,120 --> 03:05:46,240
SO WE, LET'S SAY I'VE BEEN

4433
03:05:46,240 --> 03:05:49,440
ASKING VARIOUS MEMBERS OF OUR

4434
03:05:49,440 --> 03:05:51,720
STAFF THAT TO HELP ME WITH A

4435
03:05:51,720 --> 03:05:57,120
LOOSE TO THIS PROBLEM AND TO

4436
03:05:57,120 --> 03:06:00,960
COME UP WITH THE THE POLICY THAW

4437
03:06:00,960 --> 03:06:02,600
MUST PROPOSE A STUDY ON A GENE

4438
03:06:02,600 --> 03:06:04,880
ONLY IF IT IS ACHIEVED GENE WISE

4439
03:06:04,880 --> 03:06:07,520
SIGNIFICANCE AND WE WANT TO

4440
03:06:07,520 --> 03:06:09,320
PROPOSE A IS CAROLE TO OUR

4441
03:06:09,320 --> 03:06:10,760
COMMUNITY THAT HERE IS A LIST OF

4442
03:06:10,760 --> 03:06:13,680
GENES THAT WE HAVE RELATIVELY

4443
03:06:13,680 --> 03:06:15,760
HAD HAVE ACHIEVED THAT

4444
03:06:15,760 --> 03:06:17,680
SIGNIFICANCE AND IT'S NOT AN

4445
03:06:17,680 --> 03:06:19,080
EXAUSTIVE LIST AND IT'S NOT ALL

4446
03:06:19,080 --> 03:06:21,480
GENES BECAUSE WE'RE NOT ALL

4447
03:06:21,480 --> 03:06:23,680
KNOWING AND ALL SEEING AND IT'S

4448
03:06:23,680 --> 03:06:25,280
NOT MEANT TO BE ON THIS LIST.

4449
03:06:25,280 --> 03:06:28,080
YOU CAN'T APPLY TO STUDY IT BUT

4450
03:06:28,080 --> 03:06:29,480
IT'S A LIST OF SUGGESTIONS THAT

4451
03:06:29,480 --> 03:06:34,000
WE CAN GIVE OUR COMMUNITY TO SAY

4452
03:06:34,000 --> 03:06:36,720
IT'S ACCEPTS AND GENES AND

4453
03:06:36,720 --> 03:06:37,680
HAVING GENE WIDE SIGNIFICANCE

4454
03:06:37,680 --> 03:06:39,840
AND NOT ONLY THAT, WE'RE

4455
03:06:39,840 --> 03:06:41,480
PROPOSING A LIST BUT WE'RE ALSO

4456
03:06:41,480 --> 03:06:43,680
PROPOSING A COMPANION DOCUMENT

4457
03:06:43,680 --> 03:06:45,720
AND IT EXPLAINS THE REASONING

4458
03:06:45,720 --> 03:06:48,200
AND SAYS TO OUR INVESTIGATORS IF

4459
03:06:48,200 --> 03:06:50,160
YOU HAVE A GENE THAT'S NOT ON

4460
03:06:50,160 --> 03:06:52,440
THIS LIST USE THIS REASONING AND

4461
03:06:52,440 --> 03:06:53,480
DEFINANCED YOUR DECISIONS TO

4462
03:06:53,480 --> 03:06:56,920
STUDY IT IF YOU USE A GENETIC

4463
03:06:56,920 --> 03:06:58,520
JUSTIFICATION SO THAT IS THE

4464
03:06:58,520 --> 03:06:59,000
BACKGROUND.

4465
03:06:59,000 --> 03:07:00,440
THAT'S WHAT I ASKED JOHNATHAN TO

4466
03:07:00,440 --> 03:07:05,120
COME UP WITH AND I'M GOING TO

4467
03:07:05,120 --> 03:07:06,320
TURN IT OVER THE I BELIEVE YOU

4468
03:07:06,320 --> 03:07:07,480
ALSO HAVE RECEIVED AND THEY

4469
03:07:07,480 --> 03:07:08,920
RECEIVED THE LIST, NO, THEY HAVE

4470
03:07:08,920 --> 03:07:09,120
NOT.

4471
03:07:09,120 --> 03:07:12,760
WE CAN PROVIDE IT LATER AND ALSO

4472
03:07:12,760 --> 03:07:14,280
THE COMPANION DOCUMENT IF YOU'D

4473
03:07:14,280 --> 03:07:16,120
LIKE TO REVIEW IT TO HELP US

4474
03:07:16,120 --> 03:07:17,400
MAKE SURE YOU ARE GETTING THE

4475
03:07:17,400 --> 03:07:20,600
RIGHT MESSAGE ACROSS.

4476
03:07:20,600 --> 03:07:21,000
JOHNATHAN.

4477
03:07:21,000 --> 03:07:29,080
>>THANK YOU.

4478
03:07:29,080 --> 03:07:39,480
I'M HAVING THE SLIDES.

4479
03:07:45,960 --> 03:07:47,360
IS HOW WE CREATE AND MAINTAIN

4480
03:07:47,360 --> 03:07:49,400
THE LIST AND HOW THE LIST MAY BE

4481
03:07:49,400 --> 03:07:51,240
USED AND THE PROGRAMMATIC STAFF

4482
03:07:51,240 --> 03:07:57,080
AND THE RESEARCH COMMUNITIES AND

4483
03:07:57,080 --> 03:07:59,040
IS Dr. OR JORD ON AS OUTLINED

4484
03:07:59,040 --> 03:08:06,320
A CHALLENGE WE FACE AND AND EACH

4485
03:08:06,320 --> 03:08:07,480
STAFF MAY REFER THAT

4486
03:08:07,480 --> 03:08:10,080
INVESTIGATOR TO THE 2018 REPORT

4487
03:08:10,080 --> 03:08:12,040
OF THE NATIONAL ADVISORY MENTAL

4488
03:08:12,040 --> 03:08:14,040
HEALTH COUNCIL WORKGROUP ON

4489
03:08:14,040 --> 03:08:23,520
GENOMICS AND DOCUMENT IT'S NOT

4490
03:08:23,520 --> 03:08:25,280
RESPONSIVE AND THAT P.I. MAY NOT

4491
03:08:25,280 --> 03:08:27,560
BE FAMILIAR WITH THE CRITERIA WE

4492
03:08:27,560 --> 03:08:29,800
USE AND TO DECIDE OR DETERMINE

4493
03:08:29,800 --> 03:08:31,640
WHETHER A PARTICULAR STUDY OF A

4494
03:08:31,640 --> 03:08:34,840
GENE IS RESPONSIVE AND OFTEN

4495
03:08:34,840 --> 03:08:36,320
PROGRAM STAFF DO NOT HAVE A WAY

4496
03:08:36,320 --> 03:08:37,480
TO RECEIVE FEEDBACK FROM THE

4497
03:08:37,480 --> 03:08:38,160
COMMUNITY.

4498
03:08:38,160 --> 03:08:39,320
SO WE'RE TRYING TO ADDRESS THAT

4499
03:08:39,320 --> 03:08:43,200
HERE IN THE NEXT SLIDE, PLEASE.

4500
03:08:43,200 --> 03:08:46,440
THE REPORT OF THE NATIONAL

4501
03:08:46,440 --> 03:08:47,920
ADVISORY MENTAL HEALTH COUNCIL

4502
03:08:47,920 --> 03:08:50,040
WORKGROUP WAS RELEASED IN 2018.

4503
03:08:50,040 --> 03:08:52,120
THAT WORKGROUP RECOMMENDED THAT

4504
03:08:52,120 --> 03:08:54,200
NIMH PRIORITIZED ACCORDING TO

4505
03:08:54,200 --> 03:08:55,360
RESEARCH ON GENES HAVING

4506
03:08:55,360 --> 03:08:57,200
RIGOROUS STATISTICAL SUPPORT FOR

4507
03:08:57,200 --> 03:09:00,600
ASSOCIATION TO A MENTAL ILLNESS

4508
03:09:00,600 --> 03:09:03,040
AND SPECIFICALLY THEY SHOULD

4509
03:09:03,040 --> 03:09:05,160
PASS THRESHOLDS AND IMAGE FROM

4510
03:09:05,160 --> 03:09:06,800
THAT WEBSITE WHERE THE

4511
03:09:06,800 --> 03:09:08,440
RECOMMENDATIONS WERE POSTED, IS

4512
03:09:08,440 --> 03:09:14,480
SHOWN HERE ALONG WITH A LINK.

4513
03:09:14,480 --> 03:09:24,920
GIVEN THAT GUIDANCE AND FOR

4514
03:09:30,520 --> 03:09:31,360
EXCLUDING PARTICULAR GENES.

4515
03:09:31,360 --> 03:09:32,640
SO WE'LL CONSIDER WHETHER AN

4516
03:09:32,640 --> 03:09:34,160
APPLICATION ADDRESSES THE

4517
03:09:34,160 --> 03:09:34,960
CRITERIA FOR DIGGANCE

4518
03:09:34,960 --> 03:09:37,800
RECOMMENDED IN THE COUNCIL GROUP

4519
03:09:37,800 --> 03:09:40,240
AS OPERATIONAL IN THE GENE LIST.

4520
03:09:40,240 --> 03:09:42,440
NEXT SLIDE, PLEASE.

4521
03:09:42,440 --> 03:09:44,240
SO AN OVERVIEW AND THE NEXT

4522
03:09:44,240 --> 03:09:45,040
SLIDE, PLEASE.

4523
03:09:45,040 --> 03:09:48,520
I WILL START WITH WHAT IT LOOKS

4524
03:09:48,520 --> 03:09:48,880
LIKE.

4525
03:09:48,880 --> 03:09:52,880
IT'S IN AN XL SPREAD SHEET AND

4526
03:09:52,880 --> 03:09:53,800
EACH ROW CORRESPONDS TO A GENE

4527
03:09:53,800 --> 03:09:56,400
THAT HAS 5% FALSE DISCOVERY RATE

4528
03:09:56,400 --> 03:09:58,600
FOR FDR SUPPORT AND IN SOME

4529
03:09:58,600 --> 03:10:00,240
CASES FOR ANY SUPPORT AND THAT

4530
03:10:00,240 --> 03:10:03,560
MEANS WHEN WE TALK ABOUT

4531
03:10:03,560 --> 03:10:05,800
SIGNIFICANCE THERE'S LENIENT

4532
03:10:05,800 --> 03:10:09,360
THRESHOLDS SUCH AS 5% FDR AND

4533
03:10:09,360 --> 03:10:10,120
RIGOROUS THRESHOLDS SUCH AS A

4534
03:10:10,120 --> 03:10:12,320
CORRECTION AND WE TAKE, WE

4535
03:10:12,320 --> 03:10:14,440
RECORD THE INFORMATION ON BOTH

4536
03:10:14,440 --> 03:10:17,040
OF THOSE THRESHOLDS AND

4537
03:10:17,040 --> 03:10:18,600
CURRENTLY THERE ARE 700 UNIQUE

4538
03:10:18,600 --> 03:10:21,000
GOWNS AND 1,000 GOALS AND THE

4539
03:10:21,000 --> 03:10:22,440
GOAL IS FOR THE LIST TO BE AS

4540
03:10:22,440 --> 03:10:23,840
COMPREHENSIVE AS POSSIBLE AS WE

4541
03:10:23,840 --> 03:10:25,120
UPDATE IT OVER TIME.

4542
03:10:25,120 --> 03:10:27,920
NEXT SLIDE, PLEASE.

4543
03:10:27,920 --> 03:10:29,520
FOR COMMON VARIATION THE

4544
03:10:29,520 --> 03:10:30,840
SITUATION IS DIFFERENT.

4545
03:10:30,840 --> 03:10:36,280
WE ALSO HAVE A TAB OF AN XL

4546
03:10:36,280 --> 03:10:37,760
SPREAD SHEET BUT THEY'RE

4547
03:10:37,760 --> 03:10:39,800
IDENTIFIED AND GENOME WIDE

4548
03:10:39,800 --> 03:10:41,400
ASSOCIATION STUDIES AND THOSE

4549
03:10:41,400 --> 03:10:44,160
SHOW LOW SITE WHICH REQUIRE

4550
03:10:44,160 --> 03:10:46,080
STATISTICAL FIND MAPPING TO

4551
03:10:46,080 --> 03:10:50,040
IDENTIFY SPECIFIC CAUSAL GENES

4552
03:10:50,040 --> 03:10:51,840
AND THEY HAVE 200 GENES FROM

4553
03:10:51,840 --> 03:10:53,240
SEVERAL PUBLISHED STUDIES THAT

4554
03:10:53,240 --> 03:10:55,680
ARE REPRESENTED OF WELL

4555
03:10:55,680 --> 03:10:58,000
SUPPORTED GENES FROM GWAS AS

4556
03:10:58,000 --> 03:10:59,520
OPPOSED TO BEING COMPREHENSIVE

4557
03:10:59,520 --> 03:11:00,600
IT'S REPRESENTATIVE.

4558
03:11:00,600 --> 03:11:02,760
NEXT SLIDE, PLEASE AND THE THIRD

4559
03:11:02,760 --> 03:11:04,160
PART IS A WORD DOCUMENT THAT

4560
03:11:04,160 --> 03:11:08,400
EXPLAINS THE PURPOSE AND USE OF

4561
03:11:08,400 --> 03:11:09,480
THE GENE LISTED.

4562
03:11:09,480 --> 03:11:12,120
SO HERE IS A SCREEN SHOT.

4563
03:11:12,120 --> 03:11:14,600
WHAT YOU SEE ON THIS PART OF THE

4564
03:11:14,600 --> 03:11:17,440
GENE LIST IS A LIST OF GENE

4565
03:11:17,440 --> 03:11:19,200
SYMBOLS AND THE OFFICIAL

4566
03:11:19,200 --> 03:11:21,040
APPROVED NAMES AND IDENTIFIERS

4567
03:11:21,040 --> 03:11:23,000
AND THE STRAITS SUCH AS NDD FOR

4568
03:11:23,000 --> 03:11:25,080
NEURAL DEVELOPMENT DISORDERS AND

4569
03:11:25,080 --> 03:11:26,800
SUICIDE AND SCHIZOPHRENIA AND

4570
03:11:26,800 --> 03:11:28,280
THE E. PERMENT AND THEN THE

4571
03:11:28,280 --> 03:11:29,800
SOURCE AND THERE'S A PUBMed

4572
03:11:29,800 --> 03:11:31,840
LINK FOR EACH OF THESE.

4573
03:11:31,840 --> 03:11:33,560
NEXT SLIDE, PLEASE.

4574
03:11:33,560 --> 03:11:36,400
SO, ALL GENES ON THE LIST PASS

4575
03:11:36,400 --> 03:11:38,880
5% FDR AS AN INCLUSION CRITERION

4576
03:11:38,880 --> 03:11:41,480
AND NEXT SLIDE, SOME OF THEM

4577
03:11:41,480 --> 03:11:45,400
PASS FOR STRICT OR THRESHOLD.

4578
03:11:45,400 --> 03:11:47,160
SOMETIMES ONE GENE SYMBOL IS

4579
03:11:47,160 --> 03:11:49,240
SEEN HERE ON THREE DIFFERENT

4580
03:11:49,240 --> 03:11:50,520
ROWS BECAUSE ONE GENE CAN BE

4581
03:11:50,520 --> 03:11:55,560
REPRESENTED IN MULTIPLE STUDIES.

4582
03:11:55,560 --> 03:11:57,160
NEXT PLEASE.

4583
03:11:57,160 --> 03:12:00,920
AND SO APPARENTLY THERE ARE

4584
03:12:00,920 --> 03:12:01,360
1,075 GENES.

4585
03:12:01,360 --> 03:12:03,480
ON THE NEXT SLIDE WE'LL GO ON SO

4586
03:12:03,480 --> 03:12:05,200
I'D LIKE TO ADDRESS THE QUESTION

4587
03:12:05,200 --> 03:12:07,560
HOW WAS THIS CREATE AND HOW DO

4588
03:12:07,560 --> 03:12:09,760
WE PROPOSE TO MAINTAIN IT?

4589
03:12:09,760 --> 03:12:12,800
CREATION WAS ACCOMPLISHED BY A

4590
03:12:12,800 --> 03:12:13,560
GROUP OF STAFF.

4591
03:12:13,560 --> 03:12:15,360
THERE WERE 14 OF US WHO

4592
03:12:15,360 --> 03:12:16,960
SUPPORTED DEVELOPMENT OF THE

4593
03:12:16,960 --> 03:12:17,640
GENE LIST.

4594
03:12:17,640 --> 03:12:20,280
FOR RARE VARIATION, THE BASIC

4595
03:12:20,280 --> 03:12:22,760
WORK WAS TO SEARCH THE

4596
03:12:22,760 --> 03:12:24,400
LITERATURE AND FIND SUPPLEMENTAL

4597
03:12:24,400 --> 03:12:25,880
TABLES AND PUT THEM INTO A LIST

4598
03:12:25,880 --> 03:12:29,200
WITH AN INTENTION TO BE

4599
03:12:29,200 --> 03:12:30,120
COMPREHENSION I HAVE AND

4600
03:12:30,120 --> 03:12:31,960
INCLUSION CRITERIA WHERE THERE'S

4601
03:12:31,960 --> 03:12:36,120
THE 5% OF FALSE DISCOVERY RATE.

4602
03:12:36,120 --> 03:12:38,280
SO FOR COMMON VARIATION AS I

4603
03:12:38,280 --> 03:12:39,960
MENTIONED, WE ONLY INCLUDE

4604
03:12:39,960 --> 03:12:42,480
REPRESENTATIVE EXAMPLES AND IN

4605
03:12:42,480 --> 03:12:44,400
THE FIELD THERE'S NO CONSENSUS

4606
03:12:44,400 --> 03:12:45,920
ON WHICH SPECIFIC GENES SHOULD

4607
03:12:45,920 --> 03:12:49,000
BE NOMINATED FROM MAPPING SO

4608
03:12:49,000 --> 03:12:50,760
RATHER THAN ATTEMPT TO DO THAT

4609
03:12:50,760 --> 03:12:52,720
TASK, WE SIMPLY SHOW THE KINDS

4610
03:12:52,720 --> 03:12:57,120
OF APPROACHES THAT WE FEEL ARE

4611
03:12:57,120 --> 03:12:59,280
APPROPRIATE TO TAKE.

4612
03:12:59,280 --> 03:13:01,120
NOW, HOW IS THIS GENE LIST

4613
03:13:01,120 --> 03:13:01,600
MAINTAINED?

4614
03:13:01,600 --> 03:13:03,000
WE HAVE A VERSION NUMBER FOR

4615
03:13:03,000 --> 03:13:04,720
EACH LIST AND A DATE AND WE

4616
03:13:04,720 --> 03:13:06,880
PROPOSE TO UPDATE IT REGULAR

4617
03:13:06,880 --> 03:13:09,480
INTERVALS SUCH AS ONCE EVERY

4618
03:13:09,480 --> 03:13:10,600
THREE MONTHS FOR EVERY SIX

4619
03:13:10,600 --> 03:13:11,160
MONTHS.

4620
03:13:11,160 --> 03:13:12,360
WE WELCOME FEEDBACK FROM THE

4621
03:13:12,360 --> 03:13:13,520
COMMUNITY AND EXPECT

4622
03:13:13,520 --> 03:13:14,480
INVESTIGATORS TO SUGGEST THE

4623
03:13:14,480 --> 03:13:18,240
ADDITION OF MORE GENES FROM

4624
03:13:18,240 --> 03:13:19,840
PUBLICATIONS, WE WERE APPROVED

4625
03:13:19,840 --> 03:13:22,520
WITHIN E-MAIL ADDRESS AND SO WE

4626
03:13:22,520 --> 03:13:25,640
WILL POST THIS ON AN WEBSITE

4627
03:13:25,640 --> 03:13:27,640
MAKING IT PUBLICLY ACCESSIBLE

4628
03:13:27,640 --> 03:13:29,400
AND THEN WELCOME FEEDBACK

4629
03:13:29,400 --> 03:13:30,600
THROUGH THAT' MEAL ADDRESS.

4630
03:13:30,600 --> 03:13:33,800
WE INTEND TO INTRODUCE A LIST OF

4631
03:13:33,800 --> 03:13:36,640
VARIANTS AS A FUTURE DEVELOPMENT

4632
03:13:36,640 --> 03:13:39,640
FOR CNBs THAT ARE ASSOCIATED

4633
03:13:39,640 --> 03:13:43,320
WITH MENTAL ILLNESS.

4634
03:13:43,320 --> 03:13:45,560
ARE NOW, HOW DO WE ANTICIPATE

4635
03:13:45,560 --> 03:13:48,600
THAT THIS GENE LIST WILL BE

4636
03:13:48,600 --> 03:13:49,280
USED?

4637
03:13:49,280 --> 03:13:51,600
BY PROBLEMATIC STAFF WE EXPECT

4638
03:13:51,600 --> 03:13:54,160
TO USE THE GENE LIST CONSIDERING

4639
03:13:54,160 --> 03:13:55,240
WHETHER A APPLICATION ADDRESSES

4640
03:13:55,240 --> 03:13:56,760
THE CRITERIA FOR SIGNIFICANCE

4641
03:13:56,760 --> 03:13:58,360
RECOMMENDED IN THE COUNCIL

4642
03:13:58,360 --> 03:14:01,080
WORKGROUP REPORT AND STAFF WILL

4643
03:14:01,080 --> 03:14:03,120
ENCOURAGE WELL SUPPORTED GENES

4644
03:14:03,120 --> 03:14:04,560
WHEN ASSOCIATION TO A MENTAL

4645
03:14:04,560 --> 03:14:06,840
ILLNESS IS CLAIMED AND THIS IS

4646
03:14:06,840 --> 03:14:09,120
AS OPPOSED TO CANDIDATE GENES

4647
03:14:09,120 --> 03:14:11,200
THAT NOT SUPPORTED.

4648
03:14:11,200 --> 03:14:12,680
THE DOCUMENTATION IS LANGUAGE

4649
03:14:12,680 --> 03:14:15,880
THAT MAYBE USEFUL TO PROGRAM AS

4650
03:14:15,880 --> 03:14:18,560
NIMH STAFF COMMUNICATE WITH

4651
03:14:18,560 --> 03:14:23,040
INVESTIGATORS AND I'D LIKE TO

4652
03:14:23,040 --> 03:14:27,200
THIS IS NOT AN EXCLUSIVE LIST OF

4653
03:14:27,200 --> 03:14:28,880
THE ONLY LIST STUDYING AND A

4654
03:14:28,880 --> 03:14:30,040
GUIDE TO THE THINKING OF HOW WE

4655
03:14:30,040 --> 03:14:32,680
WANT TO ADHERE TO THE GUIDANCE

4656
03:14:32,680 --> 03:14:36,200
OF THE NIMH COUNCIL REPORT.

4657
03:14:36,200 --> 03:14:38,280
IT MAY BE USEFUL FOR PLANNING

4658
03:14:38,280 --> 03:14:40,120
AND NOTICES OF FUNDING

4659
03:14:40,120 --> 03:14:42,160
OPPORTUNITIES AND ONE EXAMPLE IS

4660
03:14:42,160 --> 03:14:44,760
THE RECENTLY LAUNCHED GENES TO

4661
03:14:44,760 --> 03:14:47,000
BIOLOGY INITIATIVE CALLED SSI

4662
03:14:47,000 --> 03:14:47,880
GENE IN WHICH SEVERAL HUNDRED

4663
03:14:47,880 --> 03:14:49,760
GENES ARE TO BE STUDIED

4664
03:14:49,760 --> 03:14:50,920
FUNCTIONALLY AND THE GENE LIST

4665
03:14:50,920 --> 03:14:54,080
WOULD BE HELPFUL IN SELECTING

4666
03:14:54,080 --> 03:14:55,320
GREENS FOR A PROJECT LIKE TO AND

4667
03:14:55,320 --> 03:15:00,760
HERE, IT MAY  MAYING USEFUL FOR

4668
03:15:00,760 --> 03:15:02,160
SCIENTISTS WITH EXPERIMENTAL

4669
03:15:02,160 --> 03:15:06,800
SYSTEMS OR WELL SUPPORTED HUMAN

4670
03:15:06,800 --> 03:15:07,400
RISK GENES.

4671
03:15:07,400 --> 03:15:11,240
HOW DO WE THINK THIS -- I'M

4672
03:15:11,240 --> 03:15:12,120
GOING A EXAMPLE.

4673
03:15:12,120 --> 03:15:13,360
AN INVESTIGATOR PROPOSES

4674
03:15:13,360 --> 03:15:15,520
FUNCTIONAL STUDIES THE GENE

4675
03:15:15,520 --> 03:15:18,600
AP300 FOR ITS ROLE IN NEURAL

4676
03:15:18,600 --> 03:15:19,440
DEVELOPMENTAL DISORDERS WE CAN

4677
03:15:19,440 --> 03:15:21,400
LOOK TO THE LIST AND SEE THERE'S

4678
03:15:21,400 --> 03:15:23,240
APPROPRIATE GENOME WIDE SUPPOSE

4679
03:15:23,240 --> 03:15:24,920
AUTHORITY THIS CASE FROM THREE

4680
03:15:24,920 --> 03:15:25,840
SEPARATE STUDIES.

4681
03:15:25,840 --> 03:15:30,160
ANOTHER EXAMPLE IS YOU MAY SEE

4682
03:15:30,160 --> 03:15:31,640
ENA APPROXIMATE ON THE LIST AND

4683
03:15:31,640 --> 03:15:35,320
THEY STUDY ENO4 ENCODING 4.

4684
03:15:35,320 --> 03:15:36,960
THAT'S NOT ON THE LIST AND

4685
03:15:36,960 --> 03:15:38,800
PROGRAM MIGHT ADVISING THE

4686
03:15:38,800 --> 03:15:41,400
INVESTIGATOR THAT NIMH MAY BASIC

4687
03:15:41,400 --> 03:15:43,600
RESEARCH STUDIES OF THIS GENE

4688
03:15:43,600 --> 03:15:46,560
AND NOT AS A CANDIDATE, OR A

4689
03:15:46,560 --> 03:15:49,120
GENE, SIGNIFICANT ASSOCIATION TO

4690
03:15:49,120 --> 03:15:50,760
A PARTICULAR NOT PHENOTYPE OR

4691
03:15:50,760 --> 03:15:55,040
SUCH AS NEURO DEVELOPMENTAL

4692
03:15:55,040 --> 03:16:00,040
DISORDERS.

4693
03:16:00,040 --> 03:16:01,800
OF AND NOW APPLICANTS MAY REVIEW

4694
03:16:01,800 --> 03:16:03,080
AND THE RECOMMENDATION THAT'S

4695
03:16:03,080 --> 03:16:04,360
COME IN THE WORD DOCUMENT AS

4696
03:16:04,360 --> 03:16:14,120
THEY PREPARE GRAND APPLICATIONS

4697
03:16:14,120 --> 03:16:20,920
INVESTIGATORS THEY SUCK SUCH

4698
03:16:20,920 --> 03:16:22,320
SUPPORT AND THEY MAY CHOSE TO

4699
03:16:22,320 --> 03:16:23,240
STUDY THE PROPERTIES OF THE

4700
03:16:23,240 --> 03:16:25,400
GENES ON THIS LIST FOR EXAMPLE,

4701
03:16:25,400 --> 03:16:26,400
THEY MIGHT INTERSECT WITH THE

4702
03:16:26,400 --> 03:16:28,680
GENE LIST WITH FDA APPROVED DRUG

4703
03:16:28,680 --> 03:16:31,520
TARGETS AND STUDY PLAY

4704
03:16:31,520 --> 03:16:33,080
EVOLUTIONARY CONSTRAINT AND FOR

4705
03:16:33,080 --> 03:16:34,920
MANY OTHER KINDS OF FUNCTIONAL

4706
03:16:34,920 --> 03:16:36,080
ANNOTATION OF THE LIST AND SO

4707
03:16:36,080 --> 03:16:37,240
THIS WOULD BE AVAILABLE FOR

4708
03:16:37,240 --> 03:16:43,000
ANYONE TO DO THAT.

4709
03:16:43,000 --> 03:16:46,600
SO I'D LIKE TO CONCLUDE THE NEXT

4710
03:16:46,600 --> 03:16:47,760
SLIDE.

4711
03:16:47,760 --> 03:16:49,400
WE HAVE DEVELOPED GENE LISTS FOR

4712
03:16:49,400 --> 03:16:51,120
RARE AND COMMON VARIATION AND

4713
03:16:51,120 --> 03:16:52,760
THIS IS AN EFFORT ON OUR PART TO

4714
03:16:52,760 --> 03:16:54,800
BE RESPONSIVE TO THE 2018

4715
03:16:54,800 --> 03:16:57,320
COUNCIL WORKGROUP REPORT ON

4716
03:16:57,320 --> 03:16:59,400
GENOMICS AND NIH PROGRAM STAFF

4717
03:16:59,400 --> 03:17:02,760
PROPOSES TO OFFER THE GENE LIST

4718
03:17:02,760 --> 03:17:05,160
AND DOCUMENTATION VIA PUBLIC

4719
03:17:05,160 --> 03:17:06,920
FACING NIH WEBSITE AND MAKING IT

4720
03:17:06,920 --> 03:17:08,720
PUBLIC WE'RE TRANSPARENT ABOUT

4721
03:17:08,720 --> 03:17:10,480
THE PROCESS BY WHICH WE EVALUATE

4722
03:17:10,480 --> 03:17:10,920
GENES.

4723
03:17:10,920 --> 03:17:12,640
FOR INVESTIGATORS THE GENE LIST

4724
03:17:12,640 --> 03:17:14,040
MAY HELP PREPARE GRANT

4725
03:17:14,040 --> 03:17:15,920
APPLICATIONS WITH THE FOCUS ON

4726
03:17:15,920 --> 03:17:17,600
WELL SUPPORTED GENES AND FOR

4727
03:17:17,600 --> 03:17:19,360
STAFF THE GENE LIST MAY BE

4728
03:17:19,360 --> 03:17:20,760
HELPFUL RESOURCE WHEN

4729
03:17:20,760 --> 03:17:22,920
PRIORITIZING GRANT APPLICATIONS.

4730
03:17:22,920 --> 03:17:24,040
AND FINALLY WE HOPE INTERACT

4731
03:17:24,040 --> 03:17:25,520
WITH THE COMMUNITY TO EXPAND THE

4732
03:17:25,520 --> 03:17:26,680
GENE LIST OVER TIME AND CORRECT

4733
03:17:26,680 --> 03:17:28,320
IT AS NEEDED FOR WHEN WE LOOK

4734
03:17:28,320 --> 03:17:30,640
FORWARD TO FEEDBACK FROM THE

4735
03:17:30,640 --> 03:17:30,920
COMMUNITY.

4736
03:17:30,920 --> 03:17:33,040
I'D LIKE TO END WITH A

4737
03:17:33,040 --> 03:17:34,200
ACKNOWLEDGMENT SLIDE OF THE TEAM

4738
03:17:34,200 --> 03:17:35,880
THAT WORKED TOGETHER ON THIS

4739
03:17:35,880 --> 03:17:37,640
PROJECT AND THIS INCLUDES

4740
03:17:37,640 --> 03:17:39,720
MEMBERS OF THE DIVISION OF BASIC

4741
03:17:39,720 --> 03:17:40,560
BEHAVIORAL SCIENCE AND THE

4742
03:17:40,560 --> 03:17:42,520
DIVISION OF TRANSLATIONAL

4743
03:17:42,520 --> 03:17:43,800
RESEARCH, OFFICE OF TECHNOLOGY

4744
03:17:43,800 --> 03:17:45,320
DEVELOPMENT AND COORDINATION AND

4745
03:17:45,320 --> 03:17:48,360
THE DIVISION OF IRP AND SO THANK

4746
03:17:48,360 --> 03:17:49,760
YOU AND I'M HAPPY TO TAKE ANY

4747
03:17:49,760 --> 03:17:53,400
QUESTIONS OR HAVE ANY

4748
03:17:53,400 --> 03:17:59,920
DISCUSSION.

4749
03:17:59,920 --> 03:18:00,480
>> Joshua Gordon: ELLEN.

4750
03:18:00,480 --> 03:18:03,120
>>YES, I JUST THINK IT'S
A

4751
03:18:03,120 --> 03:18:04,360
REALLY INTERESTING RESOURCE TO

4752
03:18:04,360 --> 03:18:06,800
HAVE, ESPECIALLY IF WE ALSO

4753
03:18:06,800 --> 03:18:08,720
INCLUDED MAYBE INFORMATION ABOUT

4754
03:18:08,720 --> 03:18:10,800
SAMPLE SIZE AND THE HOMO GENEITY

4755
03:18:10,800 --> 03:18:13,320
OF THE POPULATION AND UNDER

4756
03:18:13,320 --> 03:18:16,360
STUDY I KNOW PROBABLY IT COULD

4757
03:18:16,360 --> 03:18:18,400
BE OBTAINED FROM THE REFERENCES

4758
03:18:18,400 --> 03:18:20,160
YOU PROVIDE BUT WHETHER

4759
03:18:20,160 --> 03:18:20,800
DETERMINING A PARTICULAR GENE

4760
03:18:20,800 --> 03:18:22,760
HAS REALLY ROBUST FINDINGS IT

4761
03:18:22,760 --> 03:18:24,800
WOULD BE ALSO USEFUL TO KNOW IF

4762
03:18:24,800 --> 03:18:25,760
IT WAS DONE IN A LARGE ENOUGH

4763
03:18:25,760 --> 03:18:29,160
SAMPLE SIZE ON IN A SAMPLE THAT

4764
03:18:29,160 --> 03:18:30,360
REPRESENTS THE SAMPLE THAT I'D

4765
03:18:30,360 --> 03:18:34,520
LIKE TO STUDY IN MY OWN

4766
03:18:34,520 --> 03:18:35,280
RESEARCH.

4767
03:18:35,280 --> 03:18:41,360
>>THANK YOU FOR 245
COMMENT.

4768
03:18:41,360 --> 03:18:41,840
 THAT COMMENT.

4769
03:18:41,840 --> 03:18:44,480
WE ONLY HAVE GENES THAT REQUIRES

4770
03:18:44,480 --> 03:18:46,080
INADEQUATE SAMPLE SIZE BUT I

4771
03:18:46,080 --> 03:18:47,600
WOULD LIKE TO FOLLOW-UP ON YOUR

4772
03:18:47,600 --> 03:18:49,000
SUGGESTION AND DO THAT.

4773
03:18:49,000 --> 03:18:51,760
WE ACTUALLY CAN, WE ABSOLUTELY

4774
03:18:51,760 --> 03:18:53,560
CAN INCLUDE THAT KIND OF

4775
03:18:53,560 --> 03:18:54,240
INFORMATION.

4776
03:18:54,240 --> 03:18:55,960
IN TERMS OF THE POPULATION, THAT

4777
03:18:55,960 --> 03:18:58,160
BOB A LOT MORE WORK AS EACH

4778
03:18:58,160 --> 03:19:00,400
STUDY HAS ITS OWN PARTICULAR

4779
03:19:00,400 --> 03:19:02,800
SAMPLE BUT NIMH AND OTHER

4780
03:19:02,800 --> 03:19:05,120
PROJECTS IS DEEPLY COMMITTED TO

4781
03:19:05,120 --> 03:19:08,240
INCREASING OUR UNDERSTANDING OF

4782
03:19:08,240 --> 03:19:10,200
ANCESTORIAL DIVERSITY AND

4783
03:19:10,200 --> 03:19:11,680
STUDYING MENTAL HEALTH ACROSS

4784
03:19:11,680 --> 03:19:13,480
THE GLOBE IN DIFFERENT

4785
03:19:13,480 --> 03:19:14,880
POPULATIONS WHERE THE RELEVANCE

4786
03:19:14,880 --> 03:19:18,320
OF DIFFERENT GENES MAY DIFFER.

4787
03:19:18,320 --> 03:19:19,680
>>I THINK THAT WOULD BE
VERY

4788
03:19:19,680 --> 03:19:20,920
IMPORTANT AS WE CONTINUE UP TO

4789
03:19:20,920 --> 03:19:23,680
DATE THE LIST TO MAKE SURE THAT

4790
03:19:23,680 --> 03:19:25,840
WE -- THAT IT BECOMES MORE

4791
03:19:25,840 --> 03:19:27,120
INCLUSIVE OF GENES THAT ARE

4792
03:19:27,120 --> 03:19:28,560
RELEVANT TO MORE THAN JUST THE

4793
03:19:28,560 --> 03:19:29,680
CAUCASIAN POPULATION, WHICH IS

4794
03:19:29,680 --> 03:19:31,880
THE PRIMARY SOURCE FOR MUCH OF

4795
03:19:31,880 --> 03:19:33,400
THE DATA THAT IS GOING TO BE

4796
03:19:33,400 --> 03:19:40,800
PRESENTED IN THESE LISTS.

4797
03:19:40,800 --> 03:19:41,400
>> Joshua Gordon: LAURA
--

4798
03:19:41,400 --> 03:19:44,880
>>THANK YOU, VERY MUCH.

4799
03:19:44,880 --> 03:19:48,920
SO, I AM CURIOUS ABOUT THE

4800
03:19:48,920 --> 03:19:51,200
EXACTLY WHAT RARE AND THE

4801
03:19:51,200 --> 03:19:53,400
SOURCES OF.

4802
03:19:53,400 --> 03:19:57,320
SO, I THINK THAT RARE MEANS, AT

4803
03:19:57,320 --> 03:19:58,920
THIS POINT, THE INFORMATION IS

4804
03:19:58,920 --> 03:20:02,080
COMING FROM EX ON BASED STUDIES?

4805
03:20:02,080 --> 03:20:03,440
IS THAT RIGHT?

4806
03:20:03,440 --> 03:20:06,320
WHERE YOU HAVE A CODING VARIANT

4807
03:20:06,320 --> 03:20:07,800
IN A GENE OR SOMETHING THAT

4808
03:20:07,800 --> 03:20:10,400
LOOKS LIKE IT'S IN THAT GENE.

4809
03:20:10,400 --> 03:20:10,520
O.

4810
03:20:10,520 --> 03:20:11,480
>>THAT'S RIGHT.

4811
03:20:11,480 --> 03:20:13,640
THE DEFINITION TYPICALLY IS OF A

4812
03:20:13,640 --> 03:20:15,120
PARTICULAR NOT ALLELE FREQUENCY

4813
03:20:15,120 --> 03:20:17,560
CUT OFF IN THE POPULATION WHERE

4814
03:20:17,560 --> 03:20:19,480
RARE VARIATION OCCURS AT LESS

4815
03:20:19,480 --> 03:20:21,760
THAN 1% POPULATION OF FREQUENCY

4816
03:20:21,760 --> 03:20:24,200
AND COMMON FROM GWASS INVOLVES

4817
03:20:24,200 --> 03:20:27,880
MORE FREQUENTLY OCCURRING AND

4818
03:20:27,880 --> 03:20:29,360
VARIATION SO YES IN THE RARE

4819
03:20:29,360 --> 03:20:31,320
VARIATION STUDIES TYPICALLY

4820
03:20:31,320 --> 03:20:34,120
INVOLVE FULL EX OWN OR WHOLE FEE

4821
03:20:34,120 --> 03:20:38,080
NOAM SEQUENCING AND IT FOCUS ON

4822
03:20:38,080 --> 03:20:42,000
GENES WITH BURDEN TESTS.

4823
03:20:42,000 --> 03:20:43,400
>>SO THOSE STUDIES ARE
NICE IN

4824
03:20:43,400 --> 03:20:48,680
THE SENSE THAT YOU REALLY KNOW

4825
03:20:48,680 --> 03:20:50,080
YOU THINK YOU KNOW ERRORS OF

4826
03:20:50,080 --> 03:20:51,240
BIAS AND WHAT PEOPLE HAVE DONE

4827
03:20:51,240 --> 03:20:53,680
YOU HAVE TARGETED RIGHT, AN

4828
03:20:53,680 --> 03:20:55,320
ACTUAL GENE SO I THINK THAT THAT

4829
03:20:55,320 --> 03:20:57,400
IS A GREAT IDEA.

4830
03:20:57,400 --> 03:21:01,400
FOR THE COMMON VARIATION, I

4831
03:21:01,400 --> 03:21:06,080
GUESS I WOULD LIKE TO BE ABLE TO

4832
03:21:06,080 --> 03:21:09,040
SEE HOW ACTUALLY THOSE GENES

4833
03:21:09,040 --> 03:21:11,400
HAVE GOTTEN APPLIED BECAUSE IT

4834
03:21:11,400 --> 03:21:16,880
IS HOW THOSE GENES ARE -- LET ME

4835
03:21:16,880 --> 03:21:17,760
BACK UP.

4836
03:21:17,760 --> 03:21:19,640
WITH COMMON VARIATION YOU DON'T

4837
03:21:19,640 --> 03:21:21,680
KNOW WHAT THE GENE IS.

4838
03:21:21,680 --> 03:21:23,400
YOU HAVE ALMOST NO WAY TO KNOW

4839
03:21:23,400 --> 03:21:24,880
WHAT THAT GENE IS.

4840
03:21:24,880 --> 03:21:25,440
RIGHT.

4841
03:21:25,440 --> 03:21:32,160
WITH WHAT WE KNOW AT THIS POINT.

4842
03:21:32,160 --> 03:21:42,360
PEOPLE HAVE GREEN AND IT'S

4843
03:21:42,360 --> 03:21:43,760
REALLY DIFFICULT IT COMES DOWN

4844
03:21:43,760 --> 03:21:54,280
TO I THINK STILL A CRAP SHOOT.

4845
03:22:36,960 --> 03:22:39,120
>>THANK YOU SO MUCH FOR
THESE

4846
03:22:39,120 --> 03:22:41,400
QUESTIONS AND ONE TAKES A LARGE

4847
03:22:41,400 --> 03:22:42,720
NUMBER OF INDIVIDUALS WHO ARE

4848
03:22:42,720 --> 03:22:44,880
EFFECTIVE WITH A CONDITION SUCH

4849
03:22:44,880 --> 03:22:46,360
AS 10,000 PEOPLE WITH MAJOR

4850
03:22:46,360 --> 03:22:48,800
DEPRESSIVE DISORDER AND 10,000

4851
03:22:48,800 --> 03:22:50,480
CONTROLS.

4852
03:22:50,480 --> 03:22:53,400
ONE MEASURES DNA VARIATION

4853
03:22:53,400 --> 03:22:56,600
ACROACROSS THE GENOME BY SEQUENG

4854
03:22:56,600 --> 03:22:58,120
AND ONE IDENTIFIES AND A

4855
03:22:58,120 --> 03:23:00,040
CHALLENGE COMES NOT JUST IN

4856
03:23:00,040 --> 03:23:00,920
FINDING BOTH SIDES THAT ARE

4857
03:23:00,920 --> 03:23:02,440
SIGNIFICANT BUT IN UNDERSTANDING

4858
03:23:02,440 --> 03:23:04,680
WHAT GENES ARE IN THOSE LOW SIGH

4859
03:23:04,680 --> 03:23:09,800
BECAUSE OF THE PROPERTY OF

4860
03:23:09,800 --> 03:23:12,200
LINKAGE LD AND IT MAY BE THERE

4861
03:23:12,200 --> 03:23:19,040
ARE 100 GENES IN THE LD BLOCK

4862
03:23:19,040 --> 03:23:21,760
AND IT'S NOT ENOUGH TO HAVE A

4863
03:23:21,760 --> 03:23:23,360
GENE FROM A PARTICULAR SITE AND

4864
03:23:23,360 --> 03:23:24,680
YOU NEED GO ANOTHER STEP OR TWO

4865
03:23:24,680 --> 03:23:26,600
AND EXAMPLE OF THAT STEP OR TWO

4866
03:23:26,600 --> 03:23:30,720
IS TO ADD AND SOME STATISTICS

4867
03:23:30,720 --> 03:23:34,240
RANDOMIZATION AND SMR OR TO ADD

4868
03:23:34,240 --> 03:23:36,320
TWASS STUDIES AND EVEN GENOMICS

4869
03:23:36,320 --> 03:23:38,640
STRUCTURAL EQUATION MODELING AND

4870
03:23:38,640 --> 03:23:39,680
THEY'RE DIFFERENT APPROACHES

4871
03:23:39,680 --> 03:23:41,400
THAT ARE TAKING TO GO STEP

4872
03:23:41,400 --> 03:23:48,920
FURTHER AND YOU MENTIONED EQTL

4873
03:23:48,920 --> 03:23:59,280
AND HAD AND STATISTIC

4874
03:24:19,160 --> 03:24:20,600
RANDOMIZATION AND OTHER LAYERS

4875
03:24:20,600 --> 03:24:22,400
OF EVIDENCE AS EX POLICE CAR OF

4876
03:24:22,400 --> 03:24:24,080
THE KIND OF RIG OR WE'RE LOOKING

4877
03:24:24,080 --> 03:24:24,320
FOR.

4878
03:24:24,320 --> 03:24:25,400
>>GREAT.

4879
03:24:25,400 --> 03:24:30,160
I WOULD SAY THAT HAVING WORKED

4880
03:24:30,160 --> 03:24:40,640
SOME WITH IS WHERE IT CAN BE

4881
03:24:54,080 --> 03:24:56,360
PUSHED OFF BY A SICKEL VARIANT

4882
03:24:56,360 --> 03:24:59,560
THAT HAS A STRONG EFFECT, RIGHT.

4883
03:24:59,560 --> 03:25:01,160
THAT MAY NOT HOLD UP WHEN YOU

4884
03:25:01,160 --> 03:25:09,120
LOOK AT THAT AND MAYBE IT'S A

4885
03:25:09,120 --> 03:25:16,040
LONGER CONVERSATION AT THIS

4886
03:25:16,040 --> 03:25:16,920
THINK WOULD YOU FIND THOUSANDS

4887
03:25:16,920 --> 03:25:20,280
OF GENES, RIGHT, THAT HAVE THE

4888
03:25:20,280 --> 03:25:22,800
EFFECT SO I REALLY APPRECIATE

4889
03:25:22,800 --> 03:25:26,120
THE TRYING TO NARROW DOWN AND I

4890
03:25:26,120 --> 03:25:29,120
THINK 9 TOOLS IS INCREDIBLY

4891
03:25:29,120 --> 03:25:32,000
BLUNT AND NON SPECIFIC IF IT'S.

4892
03:25:32,000 --> 03:25:33,720
>>I'LL SAY THANK YOU AND
I LOOK

4893
03:25:33,720 --> 03:25:35,160
FORWARD TO FEEDBACK ON THE

4894
03:25:35,160 --> 03:25:38,920
WRITTEN DOCUMENTATION AND ALSO

4895
03:25:38,920 --> 03:25:40,760
PRESENTS OUR APPROACH TO

4896
03:25:40,760 --> 03:25:41,800
RECOMMENDING ADDITIONAL STRENGTH

4897
03:25:41,800 --> 03:25:52,360
OF SUPPORT TO REDUCE AND IT WILL

4898
03:25:58,440 --> 03:26:08,880
BE ONE AND THE MOST IMPORTANT

4899
03:26:16,000 --> 03:26:19,760
AND AND THE AT THE MOST

4900
03:26:19,760 --> 03:26:30,120
IMPORTANT AND AND I THINK IT

4901
03:26:30,120 --> 03:26:32,520
WILL HELP AND I THINK THIS

4902
03:26:32,520 --> 03:26:42,960
TRANSPARENT AND PARTICULARLY

4903
03:26:47,840 --> 03:26:49,080
IT'S ENCOURAGING TO HAVE DETAIL

4904
03:26:49,080 --> 03:26:51,280
FOR A SHORT REPORT AND GENOMIC

4905
03:26:51,280 --> 03:26:55,720
WORKING GROUP AND I THINK THAT

4906
03:26:55,720 --> 03:27:02,280
THE COMMENTS AND ONE CAN SAY

4907
03:27:02,280 --> 03:27:04,480
THAT IN A DIFFERENT WAY AND THAT

4908
03:27:04,480 --> 03:27:07,440
IS THAT THE STUDIES THAT WE DO,

4909
03:27:07,440 --> 03:27:10,520
LOOK AT THE ASSOCIATION OF

4910
03:27:10,520 --> 03:27:13,600
PARTICULAR MUTATIONS THAT ARE

4911
03:27:13,600 --> 03:27:15,720
EITHER SNIPS OR SINGLE

4912
03:27:15,720 --> 03:27:16,880
NUCLEOTIDE VARIANTS WITH A

4913
03:27:16,880 --> 03:27:18,800
DISEASE DIAGNOSIS.

4914
03:27:18,800 --> 03:27:22,160
NOW AS YOU TEASE THAT APART

4915
03:27:22,160 --> 03:27:23,520
THERE'S A COUPLE OF CHALLENGES

4916
03:27:23,520 --> 03:27:24,040
WITH THAT.

4917
03:27:24,040 --> 03:27:25,320
THE FIRST CHALLENGE LAURA

4918
03:27:25,320 --> 03:27:27,080
POINTED OUT IS THE MUTATIONS MAY

4919
03:27:27,080 --> 03:27:29,280
NOT HAVE THE RESOLUTION THAT YOU

4920
03:27:29,280 --> 03:27:31,360
WANT AND THEY ALSO MIGHT NOT BE

4921
03:27:31,360 --> 03:27:41,880
IN GENES AND THE WORLD IS NOT

4922
03:28:19,200 --> 03:28:20,640
AND NOT JUST IS FINDING PROTEIN

4923
03:28:20,640 --> 03:28:22,600
AND I KNOW WAY TOO MUCH ABOUT IT

4924
03:28:22,600 --> 03:28:24,360
AND BUT, WHAT I WILL SAY AND IF

4925
03:28:24,360 --> 03:28:25,800
YOU LOOK AT THE MUTATIONS

4926
03:28:25,800 --> 03:28:27,280
THERE'S A GROUP OF MUTATIONS

4927
03:28:27,280 --> 03:28:30,480
THAT APPEAR TO BE LINKED TO

4928
03:28:30,480 --> 03:28:31,120
INTELLECTUAL DISABILITY AND IT

4929
03:28:31,120 --> 03:28:32,720
WAS OTHER MUTATIONS SEEM TO BE

4930
03:28:32,720 --> 03:28:36,040
LINKED TO AN AUTISM DIAGNOSIS

4931
03:28:36,040 --> 03:28:37,640
ACTUALLY AND THOSE ARE DIFFERENT

4932
03:28:37,640 --> 03:28:41,920
DOMAINS OF THE PROTEIN AND THE

4933
03:28:41,920 --> 03:28:44,920
QUEEN AND WE MIGHT STUDY A GENE

4934
03:28:44,920 --> 03:28:46,640
THAT DOES ONE THING OR ANOTHER

4935
03:28:46,640 --> 03:28:47,840
AND IT'S WORTH REALIZING THERE

4936
03:28:47,840 --> 03:28:49,600
MAY BE SOME MUTATIONS IN IT THAT

4937
03:28:49,600 --> 03:28:51,000
HAVE NOTHING TO DO WITH

4938
03:28:51,000 --> 03:28:54,680
PSYCHIATRIC DISEASE AND HAVE TO

4939
03:28:54,680 --> 03:28:58,320
DO WITH CRANIAL FACIAL SYMPTOMS

4940
03:28:58,320 --> 03:29:01,080
AND CARDIAC SYMPTOMS SO THE

4941
03:29:01,080 --> 03:29:03,120
LABEL IS NOT MUTATION AND

4942
03:29:03,120 --> 03:29:04,280
FUNCTION, AND THAT IS THE ONE

4943
03:29:04,280 --> 03:29:06,840
PART OF WHAT I SAID OF LINKING

4944
03:29:06,840 --> 03:29:07,880
MUTATIONS TO DISEASE AND LET'S

4945
03:29:07,880 --> 03:29:11,040
TALK ABOUT DISEASE.

4946
03:29:11,040 --> 03:29:13,440
AND WELL, JOSH PRESENTED

4947
03:29:13,440 --> 03:29:14,040
AGGRESSION.

4948
03:29:14,040 --> 03:29:15,400
WE WANT TO UNDERSTAND

4949
03:29:15,400 --> 03:29:16,120
AGGRESSION.

4950
03:29:16,120 --> 03:29:19,000
BECAUSE AGGRESSION IS IMPORTANT

4951
03:29:19,000 --> 03:29:23,000
PART OF A NUMBER OF PSYCHIATRIC

4952
03:29:23,000 --> 03:29:23,680
DISORDERS.

4953
03:29:23,680 --> 03:29:25,960
IT'S NOT A DISEASE DIAGNOSIS SO

4954
03:29:25,960 --> 03:29:27,840
NO GENE ON THIS LIST WILL HELP

4955
03:29:27,840 --> 03:29:30,760
US PROVIDE IN SIGHT INTO

4956
03:29:30,760 --> 03:29:31,560
AGGRESSION.

4957
03:29:31,560 --> 03:29:33,200
BRIAN IN HIS LIST OF THE

4958
03:29:33,200 --> 03:29:35,000
ACCOMPLISHMENTS OF NIMH, YOU

4959
03:29:35,000 --> 03:29:37,600
WILL NOTE, SAID THAT DRUGS WERE

4960
03:29:37,600 --> 03:29:40,120
DEVELOPED NOT FOR SCHIZOPHRENIA

4961
03:29:40,120 --> 03:29:43,600
BUT FOR PSYCHOTIC AGITATION OR

4962
03:29:43,600 --> 03:29:45,560
INFORM PSYCHOSIS WITH

4963
03:29:45,560 --> 03:29:48,080
PARKINSON'S DISEASE AND OR FOR

4964
03:29:48,080 --> 03:29:52,080
DEPRESSION THAT IS IN WOMEN

4965
03:29:52,080 --> 03:29:53,680
RELATED TO PREGNANCY AND SO ONE

4966
03:29:53,680 --> 03:29:57,720
THING I'M CONCERNED ABOUT IN

4967
03:29:57,720 --> 03:30:07,360
THIS RESTRICTION IT MAY NOT COME

4968
03:30:07,360 --> 03:30:09,760
FROM THIS LIST SO I HOPE IT

4969
03:30:09,760 --> 03:30:11,480
DOESN'T BECOME EVERYTHING IS NOT

4970
03:30:11,480 --> 03:30:12,720
IMAGINE IN THE PHILOSOPHY OF

4971
03:30:12,720 --> 03:30:15,120
THIS LIST AND I HOPE NIMH

4972
03:30:15,120 --> 03:30:16,240
REALIZES THAT THAT'S THE CASE

4973
03:30:16,240 --> 03:30:19,680
AND I WONDER IF THIS LIST WOULD

4974
03:30:19,680 --> 03:30:22,680
HAVE INFORMED US TO LOOK AT THE

4975
03:30:22,680 --> 03:30:24,120
MEDIA HYPOTHALIMUS FOR

4976
03:30:24,120 --> 03:30:27,120
AGGRESSION OR LOOK AT PARTICULAR

4977
03:30:27,120 --> 03:30:29,760
CANDIDATES TO TREAT PSYCHOTIC

4978
03:30:29,760 --> 03:30:30,920
AGITATION IN ALZHEIMER'S OR

4979
03:30:30,920 --> 03:30:32,360
PARKINSON'S SO I'M A LITTLE

4980
03:30:32,360 --> 03:30:33,400
WORRIED WE'RE BUILDING A HOUSE

4981
03:30:33,400 --> 03:30:39,040
OF CARDS ON TOP OF SOME THINGS

4982
03:30:39,040 --> 03:30:39,880
WE ARE WEARING OF WHAT WE'RE

4983
03:30:39,880 --> 03:30:43,720
DOING AND THAT'S THE MOST

4984
03:30:43,720 --> 03:30:47,560
IMPORTANT THING AND I WANT TO

4985
03:30:47,560 --> 03:30:49,000
SAY ONE LAST WORD AND IT'S

4986
03:30:49,000 --> 03:30:49,240
POLYGENIC.

4987
03:30:49,240 --> 03:30:51,200
I WANT TO THROW THAT IN THE ROOM

4988
03:30:51,200 --> 03:30:58,160
AND IN PARTICULAR, THAT'S WHAT

4989
03:30:58,160 --> 03:30:59,560
IS MENTIONED AND THE MAJORITY OF

4990
03:30:59,560 --> 03:31:00,880
DISEASE IN THE CASE OF AUTISM

4991
03:31:00,880 --> 03:31:02,600
WHICH IS A DIE SEES THAT I LIVE

4992
03:31:02,600 --> 03:31:05,360
WITH EVERYDAY WITH OUR SON.

4993
03:31:05,360 --> 03:31:07,760
HE IS NOT HAVE A SINGLE GENETIC

4994
03:31:07,760 --> 03:31:09,920
MUTATION BUT I'M SURE IT'S

4995
03:31:09,920 --> 03:31:11,760
GENETIC IN NATURE BUT IF IT IS

4996
03:31:11,760 --> 03:31:13,720
GENETIC IN NATURE IT'S POLYGENIC

4997
03:31:13,720 --> 03:31:14,840
IN NATURE SO THINKING ABOUT HOW

4998
03:31:14,840 --> 03:31:20,160
WE CAN UNDERSTAND THAT IS

4999
03:31:20,160 --> 03:31:20,640
IMPORTANT.

5000
03:31:20,640 --> 03:31:22,240
THERE'S A VERY IMPORTANT PAPER

5001
03:31:22,240 --> 03:31:24,880
LAST YEAR LOOKING AT THE 16P11

5002
03:31:24,880 --> 03:31:27,240
LOCUS WHICH IS A COPY NUMBER

5003
03:31:27,240 --> 03:31:28,880
VARIATION THAT WE STUDY IN MICE

5004
03:31:28,880 --> 03:31:31,400
AND LINKING IT TO POLYGENIC

5005
03:31:31,400 --> 03:31:32,840
COMMON VARIATIONS SO YOU DON'T

5006
03:31:32,840 --> 03:31:35,240
SEE IT LINKED TO RARE

5007
03:31:35,240 --> 03:31:35,880
VARIATIONS.

5008
03:31:35,880 --> 03:31:39,920
SO I JUST WANT TO THROW THE WORD

5009
03:31:39,920 --> 03:31:41,080
POLYGENIC INTO SPACE AFTER THAT

5010
03:31:41,080 --> 03:31:42,560
AND IT'S A LOT TO SAY AND I'M

5011
03:31:42,560 --> 03:31:45,200
LOOKING FORWARD TO THE FUTURE

5012
03:31:45,200 --> 03:31:46,200
DISCUSSIONS AND MOSTLY I HOPE

5013
03:31:46,200 --> 03:31:53,240
THIS IS A WORK IN PROGRESS THAT

5014
03:31:53,240 --> 03:31:56,760
ACKNOWLEDGES OF THE SUBTLE TEE O

5015
03:31:56,760 --> 03:31:59,760
ACHIEVE AND WE NOT LIMIT THAT.

5016
03:31:59,760 --> 03:32:01,000
>>THANK YOU.

5017
03:32:01,000 --> 03:32:01,880
>> Joshua Gordon: THANK
YOU FOR

5018
03:32:01,880 --> 03:32:03,840
ALL THOSE COMMENTS AND TIME

5019
03:32:03,840 --> 03:32:04,880
PERMITTING I'LL GIVE A BRIEF

5020
03:32:04,880 --> 03:32:07,280
ANSWER THAT I THINK THAT YOU ARE

5021
03:32:07,280 --> 03:32:12,040
COMMENT ABOUT EP300 AND CORRECT

5022
03:32:12,040 --> 03:32:14,760
BINDING PROTEIN AND YOU THINK

5023
03:32:14,760 --> 03:32:16,800
ABOUT RARE VARIATION BUT ALSO

5024
03:32:16,800 --> 03:32:18,800
ABOUT RARE DISORDERS AND THERE'S

5025
03:32:18,800 --> 03:32:22,560
SOME CONDITIONS THAT EFFECT

5026
03:32:22,560 --> 03:32:23,760
RELATIVELY FEW INDIVIDUALS.

5027
03:32:23,760 --> 03:32:26,240
AN EXAMPLE IS MUTATIONS

5028
03:32:26,240 --> 03:32:27,280
IDENTIFIED IN 17 INDIVIDUALS FOR

5029
03:32:27,280 --> 03:32:29,360
THE LOSS OF FUNCTION ALL 17 HAVE

5030
03:32:29,360 --> 03:32:31,240
THE SAME AUTISM-LIKE PHENOTYPE

5031
03:32:31,240 --> 03:32:33,840
AND THEY'RE LIKELY TO BE GENES

5032
03:32:33,840 --> 03:32:34,760
THAT WILL NEVER REACH

5033
03:32:34,760 --> 03:32:39,280
SIGNIFICANCE AND THE MEDICAL

5034
03:32:39,280 --> 03:32:40,520
GENETICS WILL LIST THOSE AND

5035
03:32:40,520 --> 03:32:43,040
WHICH ARE REALLY A DIFFERENT

5036
03:32:43,040 --> 03:32:45,120
EMPHASIS THAN HERE AND IN THIS

5037
03:32:45,120 --> 03:32:46,320
CONTEXT, THERE ARE MANY

5038
03:32:46,320 --> 03:32:50,160
INVESTIGATORS WHO WANT TO STUDY

5039
03:32:50,160 --> 03:32:52,040
GENE AND SUGGEST IT'S FOR AUTISM

5040
03:32:52,040 --> 03:32:53,640
OR RELATED TO AUTISM OR

5041
03:32:53,640 --> 03:32:56,240
ASSOCIATED WITH AUTISM AND THE

5042
03:32:56,240 --> 03:32:58,080
DATA DON'T SHOW THAT SO WE'RE

5043
03:32:58,080 --> 03:33:01,840
MAKING SURE THAT THAT WORK IS

5044
03:33:01,840 --> 03:33:03,280
PROPERLY CLAIMING SEWIZATION BUT

5045
03:33:03,280 --> 03:33:05,160
NOT IN NAME TRYING TO BE

5046
03:33:05,160 --> 03:33:07,680
RESTRICTIVE ABOUT STUDYING RARE

5047
03:33:07,680 --> 03:33:09,160
VARIATION IN THE GENE, I GUESS,

5048
03:33:09,160 --> 03:33:14,400
THE CASE THAT EP300 IS ON THE

5049
03:33:14,400 --> 03:33:14,600
LIST.

5050
03:33:14,600 --> 03:33:16,360
>>I DON'T KNOW IF IT'S
NOT THE

5051
03:33:16,360 --> 03:33:18,120
LIST BUT IT SHOWS UP NOW.

5052
03:33:18,120 --> 03:33:19,360
SO, YEAH.

5053
03:33:19,360 --> 03:33:21,200
>>SO A BROADER IDEA IS
WHAT ARE

5054
03:33:21,200 --> 03:33:23,160
WE TRYING TO DO?

5055
03:33:23,160 --> 03:33:26,960
IT'S ABOUT SCIENTIFIC RIGOR AND

5056
03:33:26,960 --> 03:33:29,400
MAKE SURE ONE DOESN'T STUDY A

5057
03:33:29,400 --> 03:33:30,840
FAVORITE GENE WHICH SEEMS

5058
03:33:30,840 --> 03:33:32,360
APPEALING BUT NOT ASSOCIATED TO

5059
03:33:32,360 --> 03:33:34,040
A CONDITION.

5060
03:33:34,040 --> 03:33:35,880
IN TERMS OF POLYGENIC THANK YOU

5061
03:33:35,880 --> 03:33:37,280
FOR MENTIONING THAT WORD AND

5062
03:33:37,280 --> 03:33:38,440
THESE DISORDERS OFTEN ARE IN

5063
03:33:38,440 --> 03:33:41,080
TERMS OF BRIAN'S COMMENTS AND

5064
03:33:41,080 --> 03:33:51,520
FOR Dr. ROSS IN TERMS OF

5065
03:33:51,880 --> 03:33:52,600
PHENOTYPES THAT NEED TO BE

5066
03:33:52,600 --> 03:33:53,680
CONSIDERED IN AGGRESSION AND

5067
03:33:53,680 --> 03:33:54,960
DIFFERENT KINDS OF AGGRESSION

5068
03:33:54,960 --> 03:33:58,360
EVEN AND ONE CAN GO TO HUMAN

5069
03:33:58,360 --> 03:33:59,960
GENOTYPE ONCOLOGY AND GET A LIST

5070
03:33:59,960 --> 03:34:01,400
OF GENES AND USE THIS LIST TO

5071
03:34:01,400 --> 03:34:03,000
UNDERSTAND WHICH OF THOSE

5072
03:34:03,000 --> 03:34:03,720
ALREADY HAVE GINO WIDE SUPPORT

5073
03:34:03,720 --> 03:34:05,800
TO KNOW WHICH OF THEM MIGHT BE

5074
03:34:05,800 --> 03:34:07,320
APPROPRIATE TO STUDY OR MIGHT BE

5075
03:34:07,320 --> 03:34:08,640
HELPFUL TO STUDY SO THIS CAN BE

5076
03:34:08,640 --> 03:34:10,480
A GUIDE AND I WANT TO AGREE WITH

5077
03:34:10,480 --> 03:34:13,920
YOUR COMMENT ABOUT OUR INTEREST

5078
03:34:13,920 --> 03:34:16,400
IN BEING TRANSPAR TRANSPARENT AE

5079
03:34:16,400 --> 03:34:17,760
ARE MANY DIFFERENT APPROACHES TO

5080
03:34:17,760 --> 03:34:19,520
THIS PROGRAM AND THAT WE'RE

5081
03:34:19,520 --> 03:34:20,560
SUPPORTIVE OF HEARING FROM THE

5082
03:34:20,560 --> 03:34:23,160
COMMUNITY AND FROM COUNCIL NOW

5083
03:34:23,160 --> 03:34:26,160
ABOUT BEST WAYS TO GO FORWARD.

5084
03:34:26,160 --> 03:34:28,040
>>LET ME JUST EMPHASIZE,
THIS

5085
03:34:28,040 --> 03:34:29,640
IS AGAIN, IT'S A SET OF MY

5086
03:34:29,640 --> 03:34:30,000
INTRODUCTION.

5087
03:34:30,000 --> 03:34:31,520
THIS IS NOT MEANT TO BE

5088
03:34:31,520 --> 03:34:32,000
RESTRICTIVE.

5089
03:34:32,000 --> 03:34:32,560
WE HAVE THAT.

5090
03:34:32,560 --> 03:34:33,600
WE HAVE THAT DOWN.

5091
03:34:33,600 --> 03:34:35,080
WE RESTRICT ALL THE TIME.

5092
03:34:35,080 --> 03:34:37,400
AND IN FACT, UNFORTUNATELY WE

5093
03:34:37,400 --> 03:34:38,360
RESTRICT WITHOUT TRANSPARENCY

5094
03:34:38,360 --> 03:34:39,760
BECAUSE IT'S REALLY HARD TO

5095
03:34:39,760 --> 03:34:42,040
CREATE A LIST OF GENES THAT WE

5096
03:34:42,040 --> 03:34:43,320
WON'T STUDY, RIGHT.

5097
03:34:43,320 --> 03:34:44,680
THIS IS MEANT TO BE THE OTHER

5098
03:34:44,680 --> 03:34:50,480
END OF THE SPECTRUM AND WE WANT

5099
03:34:50,480 --> 03:34:55,120
2TO PINT PEOPLE TO GENES AND ITS

5100
03:34:55,120 --> 03:34:56,160
NOT MEANT TO BE THE ONLY PIECE

5101
03:34:56,160 --> 03:34:57,520
OF INFORMATION TO DEVICE A

5102
03:34:57,520 --> 03:34:59,880
STRATEGY FOR STUDYING THINGS.

5103
03:34:59,880 --> 03:35:01,960
SO YEAH, IF THEY WANT TO STUDY

5104
03:35:01,960 --> 03:35:04,600
EP300 AND SUGGEST A KNOCKOUT

5105
03:35:04,600 --> 03:35:05,760
THEY BEST DAMN BE SURE THAT

5106
03:35:05,760 --> 03:35:08,040
THAT'S THE RIGHT ONE AND JUSTIFY

5107
03:35:08,040 --> 03:35:09,400
THAT ON THE GRANT.

5108
03:35:09,400 --> 03:35:11,200
>>THANK YOU, JOHNATHAN.

5109
03:35:11,200 --> 03:35:12,120
I APPRECIATE THE PRESENTATION

5110
03:35:12,120 --> 03:35:14,280
AND THE FEEDBACK.

5111
03:35:14,280 --> 03:35:15,480
WE HAVE SOME DISCUSS ON THE

5112
03:35:15,480 --> 03:35:16,760
COMMON VARIATION BETWEEN YOU AND

5113
03:35:16,760 --> 03:35:18,640
ME AND BEFORE WE MOVE FORWARD.

5114
03:35:18,640 --> 03:35:23,800
>>I JUST A COMMENT AND
WE'VE

5115
03:35:23,800 --> 03:35:27,600
HEARD COMMENTS AGAINST THIS AND

5116
03:35:27,600 --> 03:35:30,320
I THINK THIS IS A GREAT IDEA.

5117
03:35:30,320 --> 03:35:34,000
FOR THOSE OF YOU WHO HAVEN'T

5118
03:35:34,000 --> 03:35:36,240
SORT FOLLOWED THIS AREA FOR

5119
03:35:36,240 --> 03:35:37,640
DECADES, THERE ARE REALLY SORT

5120
03:35:37,640 --> 03:35:42,480
OF NOTORIOUS CASES OF GENES THAT

5121
03:35:42,480 --> 03:35:45,120
HAVE SOPPED UP VAST SUMS OF

5122
03:35:45,120 --> 03:35:45,840
MONEY PARTICULARLY IN MENTAL

5123
03:35:45,840 --> 03:35:48,080
HEALTH THAT WERE SHOWN IN GINO

5124
03:35:48,080 --> 03:35:52,200
ONE ASSOCIATION STUDIES AND NOT

5125
03:35:52,200 --> 03:35:57,960
TO BE ANYWHERE -- NOT TO BE

5126
03:35:57,960 --> 03:35:58,600
(INAUDIBLE).

5127
03:35:58,600 --> 03:36:01,400
AND I KNOW AS A REVIEWER, WHEN I

5128
03:36:01,400 --> 03:36:02,840
WOULD REVIEW THESE GRANTS, I

5129
03:36:02,840 --> 03:36:05,400
WOULD HAVE TO DIG INTO THE

5130
03:36:05,400 --> 03:36:07,920
PRIMARY LITERATURE MYSELF AND

5131
03:36:07,920 --> 03:36:10,760
IT'S GREAT THAT THIS IS HERE NOW

5132
03:36:10,760 --> 03:36:14,800
AND SO YOU KNOW AT SOME POINT IN

5133
03:36:14,800 --> 03:36:25,240
THE FUTURE, AND ONE OF THE

5134
03:36:29,880 --> 03:36:37,880
THINGS THAT WHEEL FROM THIS IS A

5135
03:36:37,880 --> 03:36:39,120
LOT OF THE VACCINES LINKED TO

5136
03:36:39,120 --> 03:36:40,200
PSYCHIATRIC DISEASES PEOPLE WILL

5137
03:36:40,200 --> 03:36:41,000
STUDY THEM BECAUSE THEY'RE ON

5138
03:36:41,000 --> 03:36:45,120
THE LIST AND THEY'LL THINK NIH

5139
03:36:45,120 --> 03:36:47,800
IS INTERESTED AND SO YOU WILL

5140
03:36:47,800 --> 03:36:48,840
SEE GRANTS AND IT'S A GREAT

5141
03:36:48,840 --> 03:36:49,040
THING.

5142
03:36:49,040 --> 03:36:53,120
>>I APPRECIATE THE
POSITIVE

5143
03:36:53,120 --> 03:36:54,720
FEEDBACK.

5144
03:36:54,720 --> 03:36:56,240
I APPRECIATE THE DISCUSSION

5145
03:36:56,240 --> 03:36:58,440
WE'VE HAD SO FAR AND IT WILL BE

5146
03:36:58,440 --> 03:37:00,160
AN ONGOING GIVE-AND-TAKE.

5147
03:37:00,160 --> 03:37:04,000
JUST A MOTEL A NOTE TO CHRISTOPD

5148
03:37:04,000 --> 03:37:05,360
PAULINE, WE HAVE TO POSTPONE

5149
03:37:05,360 --> 03:37:08,320
YOUR PRESENTATIONS TO THE NEXT

5150
03:37:08,320 --> 03:37:09,040
COUNCIL ON THE KUM PES PROGRAM.

5151
03:37:09,040 --> 03:37:10,880
THIS IS REALLY EXCITING PROGRAM

5152
03:37:10,880 --> 03:37:12,160
AND WE WILL BRING TO COUNCIL AND

5153
03:37:12,160 --> 03:37:14,160
WE WANT YOU ALL TO HEAR ABOUT IT

5154
03:37:14,160 --> 03:37:16,080
AND UNDERSTAND THAT NIH ROLE BUT

5155
03:37:16,080 --> 03:37:17,160
WE DON'T HAVE TIME TODAY.

5156
03:37:17,160 --> 03:37:18,560
WE'RE GOING TO MOVE TO THE NEXT

5157
03:37:18,560 --> 03:37:22,000
ITEM ON THE AGENDA WHICH IS

5158
03:37:22,000 --> 03:37:26,160
Dr. NITA FARAHANY TO JOIN US

5159
03:37:26,160 --> 03:37:32,000
TO TELL US ABOUT A CONSULTATION

5160
03:37:32,000 --> 03:37:33,120
BRAIN ETHNIC WORKING GROUP AND

5161
03:37:33,120 --> 03:37:35,480
NIH IS ONE OF THE TWO SUITS AND

5162
03:37:35,480 --> 03:37:37,040
ONE OF 10 DIFFERENT INSTITUTES

5163
03:37:37,040 --> 03:37:37,960
AND SUPPORTS THE BRAIN

5164
03:37:37,960 --> 03:37:39,600
INITIATIVE AND THERE'S A STRONG

5165
03:37:39,600 --> 03:37:41,200
NEUROETHICS COMPONENT TO THE

5166
03:37:41,200 --> 03:37:42,080
BRAIN INITIATIVE AND ONE OF

5167
03:37:42,080 --> 03:37:47,080
THOSE COMPONENTS IS TO PERFORM

5168
03:37:47,080 --> 03:37:48,120
CONSULTATIONS TO GRANTS AND

5169
03:37:48,120 --> 03:37:49,960
PROGRAMS THAT MIGHT RAISE NEURO

5170
03:37:49,960 --> 03:37:51,280
ETHICAL ISSUES AND FROM TIME TO

5171
03:37:51,280 --> 03:37:52,800
TIME, THOSE ARE DISCUSSED IN THE

5172
03:37:52,800 --> 03:37:53,960
WORKING GROUP AND THEY NEED TO

5173
03:37:53,960 --> 03:37:55,680
BE PRESENTED AT A OPEN SESSION

5174
03:37:55,680 --> 03:37:58,760
OF A COUNCIL IN ORDER FOR BRAIN

5175
03:37:58,760 --> 03:38:00,480
STAFF TO BE ABLE TO TAKE THAT

5176
03:38:00,480 --> 03:38:01,640
ADVICE AND HAND AND THAT'S WHAT

5177
03:38:01,640 --> 03:38:02,640
WE'RE DOING TODAY AND WE'RE

5178
03:38:02,640 --> 03:38:08,400
GOING TO HEAR FROM Dr.

5179
03:38:08,400 --> 03:38:10,040
FARAHANY AND A CO-CHAIR IN THE

5180
03:38:10,040 --> 03:38:12,360
BRAIN NEURO ETHICS WORKING GROUP

5181
03:38:12,360 --> 03:38:14,320
AND SHE COMES TO US TO SHARE

5182
03:38:14,320 --> 03:38:15,760
SOME CONSIDERATION FROM THAT

5183
03:38:15,760 --> 03:38:18,400
GROUP ON SHARING AND ACCESS OF

5184
03:38:18,400 --> 03:38:19,720
GENOMIC SEQUENCING DATA AND THIS

5185
03:38:19,720 --> 03:38:21,600
IS FOR YOUR AWARENESS.

5186
03:38:21,600 --> 03:38:23,080
THERE'S NO VOTE AFTERWARDS AND

5187
03:38:23,080 --> 03:38:25,800
Dr. FARAHANY, DID YOU FOR

5188
03:38:25,800 --> 03:38:28,840
JOINING IS.

5189
03:38:28,840 --> 03:38:39,120
>>AND COULD YOU GO TO THE
NEXT

5190
03:38:39,120 --> 03:38:39,480
SLIDE, PLEASE.

5191
03:38:39,480 --> 03:38:41,520
SO,  I WANTED TO BEGIN JUST BY

5192
03:38:41,520 --> 03:38:45,680
GIVING YOU AN OVERVIEW OF THE

5193
03:38:45,680 --> 03:38:47,440
BRAIN INITIATIVE ATLAS NETWORK

5194
03:38:47,440 --> 03:38:52,080
TO THEN GET INTO THE CONTEXT OF

5195
03:38:52,080 --> 03:38:54,840
THE CONSULTATION THAT WE DID AND

5196
03:38:54,840 --> 03:38:57,080
SO THE OL HERE IS BUILDING

5197
03:38:57,080 --> 03:38:58,400
REFERENCE BRAIN DIALYSIS THAT

5198
03:38:58,400 --> 03:38:59,520
WILL BE USED THROUGHOUT THE

5199
03:38:59,520 --> 03:39:00,640
COMMUNITY WHICH GIVES THE

5200
03:39:00,640 --> 03:39:02,160
FOUNDATIONAL FRAMEWORK FOR CROSS

5201
03:39:02,160 --> 03:39:04,440
SPECIES STUDY OF BRAIN EVOLUTION

5202
03:39:04,440 --> 03:39:06,960
AND FUNCTION AND INVOLVES THE

5203
03:39:06,960 --> 03:39:13,040
COLLECTION OF BRAIN SPECIMENS

5204
03:39:13,040 --> 03:39:23,560
AND ALLOWS FOR LARGE-SCALE HUMAN

5205
03:39:36,720 --> 03:39:38,040
DENOAM I CAN TO BE SHARED AND

5206
03:39:38,040 --> 03:39:38,880
UNDER RESTRICTED OR CONTROLLED

5207
03:39:38,880 --> 03:39:40,080
MANNER BASED ON WHICH APPROACH

5208
03:39:40,080 --> 03:39:41,680
IS INDICATED IN INSTITUTIONAL

5209
03:39:41,680 --> 03:39:42,960
CERTIFICATION FORMS THAT ARE

5210
03:39:42,960 --> 03:39:44,960
PROVIDED BY THE INSTITUTIONS AND

5211
03:39:44,960 --> 03:39:47,400
CURRENTLY THE BUY CAN FOA

5212
03:39:47,400 --> 03:39:48,760
STIPULATE LATE DATA TO BE SHARED

5213
03:39:48,760 --> 03:39:50,640
VIA OPEN AND UNRESTRICTED ACCESS

5214
03:39:50,640 --> 03:39:54,920
AND IT'S THAT POINT WE WANTED TO

5215
03:39:54,920 --> 03:39:57,200
FOCUS ON.

5216
03:39:57,200 --> 03:39:59,000
SO, NIH OF COURSE NAMES TO HAVE

5217
03:39:59,000 --> 03:40:00,960
GOOD DATA STEWARDSHIP WHILE MACK

5218
03:40:00,960 --> 03:40:05,560
HIMAXIMIZINGDATA SHARING AND THE

5219
03:40:05,560 --> 03:40:07,440
IN CONTENTION WITH ONE ANOTHER

5220
03:40:07,440 --> 03:40:08,720
AND OTHER NIH INITIATIVES HAVE

5221
03:40:08,720 --> 03:40:11,560
USED OPEN AND UNRESTRICTED

5222
03:40:11,560 --> 03:40:15,200
ACCESS AND USING PUBLICLY

5223
03:40:15,200 --> 03:40:16,800
AVAILABLE DATA OR CONTROLLED OR

5224
03:40:16,800 --> 03:40:17,640
TIER ACCESS WHICH REQUIRES A

5225
03:40:17,640 --> 03:40:19,080
REQUEST WITH RELEVANT

5226
03:40:19,080 --> 03:40:20,520
DOCUMENTATION AND WHILE

5227
03:40:20,520 --> 03:40:21,240
INSTITUTIONAL CERTIFICATIONS MAY

5228
03:40:21,240 --> 03:40:23,080
ALLOW GRANTEE INSTITUTIONS TO

5229
03:40:23,080 --> 03:40:24,920
AFFIRM THAT SUBJECTS HAVE

5230
03:40:24,920 --> 03:40:26,560
CONSENTED, TO ALLOW THEIR

5231
03:40:26,560 --> 03:40:28,320
GENOMIC DATA TO BE SHARED

5232
03:40:28,320 --> 03:40:31,760
THROUGH UNRESTRICTED OR OPEN

5233
03:40:31,760 --> 03:40:33,960
ACCESS AND IMPLEMENTATION IS

5234
03:40:33,960 --> 03:40:35,520
PRIMARY SEQUENCE DATA IS TO BE

5235
03:40:35,520 --> 03:40:36,520
MANAGED THROUGH CONTROLLED

5236
03:40:36,520 --> 03:40:38,280
ACCESS AND REGARDLESS OF HOW THE

5237
03:40:38,280 --> 03:40:40,560
SUBJECTS HAVE CONSENTED AND THE

5238
03:40:40,560 --> 03:40:42,760
NIH OFFICE OF EXTRAMURAL

5239
03:40:42,760 --> 03:40:45,200
RESEARCH HAS INDICATED THEY

5240
03:40:45,200 --> 03:40:48,080
WOULD CONSIDER A NIH CONVENED

5241
03:40:48,080 --> 03:40:49,160
BIOETHICS CONSULTATION AND THEIR

5242
03:40:49,160 --> 03:40:50,000
DELIBERATIONS ON THIS MATTER

5243
03:40:50,000 --> 03:40:54,080
WHICH IS WHAT WE'RE TALKING

5244
03:40:54,080 --> 03:40:58,880
ABOUT HERE.

5245
03:40:58,880 --> 03:41:05,000
SO, ON JANUARY THEY, THEY HAD A

5246
03:41:05,000 --> 03:41:06,320
CONSULT RELATED TO UNPRESELECTED

5247
03:41:06,320 --> 03:41:10,160
TO SEQUENCE DATA AND WE STARTED

5248
03:41:10,160 --> 03:41:13,320
THIS CONSULTATION FROM WITH THE

5249
03:41:13,320 --> 03:41:15,600
BRAIN STAFF THAT PROVIDED

5250
03:41:15,600 --> 03:41:17,080
BACKGROUND MATERIALS WHICH

5251
03:41:17,080 --> 03:41:18,240
INCLUDED AN OVERVIEW OF THE

5252
03:41:18,240 --> 03:41:20,760
CONSULT REQUEST, GENETIC DATA

5253
03:41:20,760 --> 03:41:22,040
SHARING LANGUAGE FROM

5254
03:41:22,040 --> 03:41:23,400
PROCUREMENT SITES AND

5255
03:41:23,400 --> 03:41:24,000
INSTITUTIONAL CERTIFICATION

5256
03:41:24,000 --> 03:41:26,600
FORMS AND INSTITUTIONAL SPECIFIC

5257
03:41:26,600 --> 03:41:29,520
CONSENT FORMS AND WE HEARD FROM

5258
03:41:29,520 --> 03:41:36,760
EXPERTS THAT Dr. DAVID

5259
03:41:36,760 --> 03:41:39,080
PANCHENSO H AND ELLEN CLAYTON AD

5260
03:41:39,080 --> 03:41:40,760
WE INVITED THESE FOLKS BOTH TO

5261
03:41:40,760 --> 03:41:44,360
GIVE US AN UPDATE ABOUT THESE

5262
03:41:44,360 --> 03:41:45,760
DIFFERENT POLICIES AND Dr.

5263
03:41:45,760 --> 03:41:48,200
CLAYTON WHO HAS DONE RESEARCH ON

5264
03:41:48,200 --> 03:41:49,920
THE ETHNIC OF DATA SHARING WITH

5265
03:41:49,920 --> 03:41:51,120
GENOMIC DATA OUGHT TO BE.

5266
03:41:51,120 --> 03:41:52,160
THIS SUMMARY PRESENTS WHAT WAS

5267
03:41:52,160 --> 03:41:53,920
HEARD FROM THE SPEAKERS AND THE

5268
03:41:53,920 --> 03:41:56,280
SUBSEQUENT DISCUSSIONS THAT THEY

5269
03:41:56,280 --> 03:41:57,640
HAD AND NOT AWFUL THE POINTS

5270
03:41:57,640 --> 03:42:08,160
THAT ARE IN HERE MAY BE SO THE

5271
03:42:13,360 --> 03:42:14,200
DISCUSSION QUESTIONS WERE FIRST

5272
03:42:14,200 --> 03:42:17,400
WHAT ARE THE POTENTIAL RISKS OF

5273
03:42:17,400 --> 03:42:19,840
HAVING UNPREDICTED OR OPEN

5274
03:42:19,840 --> 03:42:20,560
VERSUS CONTROLLED OR TIRED DATA

5275
03:42:20,560 --> 03:42:22,400
ACCESS TO PRIMARY SEQUENCE DATA

5276
03:42:22,400 --> 03:42:25,160
OF LIVING VERSUS DECEASED

5277
03:42:25,160 --> 03:42:27,440
PARTICIPANTS AND SOME OF THE

5278
03:42:27,440 --> 03:42:29,800
MISUSE CONCERNS NOT OF SHARED

5279
03:42:29,800 --> 03:42:31,720
PRIMARY DATA SEQUENCE COULD

5280
03:42:31,720 --> 03:42:33,440
INVOLVE FOR EXAMPLE ANY RISK TO

5281
03:42:33,440 --> 03:42:34,480
PARTICIPANTS IF LIVING RATHER

5282
03:42:34,480 --> 03:42:38,320
THAN POSTMORTEM RECIPIENTS,

5283
03:42:38,320 --> 03:42:39,360
POSTMORTEM INDIVIDUALS

5284
03:42:39,360 --> 03:42:40,960
PARTICIPANTS FAMILY MEMBERS OF

5285
03:42:40,960 --> 03:42:41,920
PARTICIPANTS WHO DIDN'T CONSENT

5286
03:42:41,920 --> 03:42:43,960
TO THE RESEARCH BUT OBVIOUSLY

5287
03:42:43,960 --> 03:42:46,080
COULD BE EITHER IDENTIFIED OR I

5288
03:42:46,080 --> 03:42:47,960
IMPLICATED AS A RESULT OF THE

5289
03:42:47,960 --> 03:42:49,320
GENETIC SEQUENCING DATA AND

5290
03:42:49,320 --> 03:42:53,080
COMMUNITIES AND SOCIETIES WHERE

5291
03:42:53,080 --> 03:42:53,880
THERE'S LITERATURE AND

5292
03:42:53,880 --> 03:42:55,840
SCHOLARSHIP AROUND THE

5293
03:42:55,840 --> 03:42:57,160
IMPLICATIONS FOR COMMUNITIES AND

5294
03:42:57,160 --> 03:42:58,200
SOCIETIES WITH RESPECT TO THE

5295
03:42:58,200 --> 03:43:05,040
SHARING OF GENOMIC DATA AND ANY

5296
03:43:05,040 --> 03:43:11,120
RISK OF HARM THAT MAY PLOW FROM

5297
03:43:11,120 --> 03:43:16,720
REIDENTIFICATION AND THE RISK OF

5298
03:43:16,720 --> 03:43:18,320
OPEN DATA SHARING TO THEMSELVES

5299
03:43:18,320 --> 03:43:20,520
AND THEIR FAMILY MEMBERS AND

5300
03:43:20,520 --> 03:43:22,240
WHETHER IT'S EFFICIENT FOR FULLY

5301
03:43:22,240 --> 03:43:24,160
INFORMED CONSENT LOOK LIKE IN

5302
03:43:24,160 --> 03:43:25,120
THAT CONTEXT.

5303
03:43:25,120 --> 03:43:30,640
NEXT SLIDE, PLEASE.

5304
03:43:30,640 --> 03:43:33,880
SO WE DISCUSSED THE POTENTIAL

5305
03:43:33,880 --> 03:43:36,880
RISK OF UNRESTRICTED OPEN AND

5306
03:43:36,880 --> 03:43:39,480
TIRED DATA ACCESS TO PRIMARY

5307
03:43:39,480 --> 03:43:40,920
SEQUENCE DATA OF LIVING AND

5308
03:43:40,920 --> 03:43:43,400
DECEASED PATIENTS WOULD BE SO

5309
03:43:43,400 --> 03:43:44,080
CONTINUING THAT CONVERSATION

5310
03:43:44,080 --> 03:43:45,680
THERE MAY NOT EXIST CLEAR

5311
03:43:45,680 --> 03:43:48,400
EVIDENCE OF QUANTIFYING A

5312
03:43:48,400 --> 03:43:50,240
DIFFERENT IN RISK BETWEEN OPEN

5313
03:43:50,240 --> 03:43:51,920
AND CONTROLLED SHARING THAT IS

5314
03:43:51,920 --> 03:43:53,320
THERE'S NOT BEEN ENOUGH RESEARCH

5315
03:43:53,320 --> 03:43:54,760
TO REALLY LOOK AT THESE

5316
03:43:54,760 --> 03:43:56,360
DIFFERENCES AND WHAT THE

5317
03:43:56,360 --> 03:43:57,080
IMPLICATIONS MAY BE.

5318
03:43:57,080 --> 03:44:00,600
A DATA ACCESS OR REVIEW

5319
03:44:00,600 --> 03:44:02,280
COMMITTEE WOULD BE LIKELY TO

5320
03:44:02,280 --> 03:44:03,640
REDUCE THE LIKELY HOOD OF

5321
03:44:03,640 --> 03:44:05,600
REIDENTIFICATION OR USES THAT

5322
03:44:05,600 --> 03:44:06,560
COULD CAUSE COMMUNITY HARMS AND

5323
03:44:06,560 --> 03:44:08,520
COULD LIMIT THE USE TO

5324
03:44:08,520 --> 03:44:10,040
SCIENTIFIC PURPOSES AS OPPOSED

5325
03:44:10,040 --> 03:44:11,520
TO SOME OF THE MISUSE CONCERNS

5326
03:44:11,520 --> 03:44:14,680
FOR LEGAL OR COMMERCIAL OR OTHER

5327
03:44:14,680 --> 03:44:16,280
PURPOSES AND CONTROLLED ACCESS

5328
03:44:16,280 --> 03:44:19,360
INVOLVED RESEARCH INSTITUTIONS

5329
03:44:19,360 --> 03:44:21,000
AND OFTEN TIMES REDUCE THE RISK

5330
03:44:21,000 --> 03:44:22,640
OVER ALL AND PARTICULARLY GIVEN

5331
03:44:22,640 --> 03:44:24,760
THAT SOME OF THE HARMS THAT WERE

5332
03:44:24,760 --> 03:44:26,160
IDENTIFIED WOULD BE FROM EXTRA

5333
03:44:26,160 --> 03:44:27,560
RESEARCH INSTITUTIONS NOT FROM

5334
03:44:27,560 --> 03:44:29,520
RESEARCH INSTITUTIONS THEMSELVES

5335
03:44:29,520 --> 03:44:30,640
AND THEN CONCERNS ABOUT THE

5336
03:44:30,640 --> 03:44:36,280
EFFECT OF OPEN SHARING ON

5337
03:44:36,280 --> 03:44:38,800
POTENTIAL THEY HAD SHOWN SCIO

5338
03:44:38,800 --> 03:44:39,360
DEMOGRAPHIC VARIABLES AND

5339
03:44:39,360 --> 03:44:40,600
WILLINGNESS TO PARTICIPATE IN

5340
03:44:40,600 --> 03:44:43,040
RESEARCH THAT INVOLVED DATA

5341
03:44:43,040 --> 03:44:44,240
SHARING AND COMMUNITY ENGAGEMENT

5342
03:44:44,240 --> 03:44:46,280
COULD BE ONE WAY TO MITIGATE

5343
03:44:46,280 --> 03:44:46,800
THESE CONCERNS.

5344
03:44:46,800 --> 03:44:51,880
OF COURSE, MISUSE OF DATA WOULD

5345
03:44:51,880 --> 03:44:56,400
NEGATIVELY IMPACT SO THIS WAS A

5346
03:44:56,400 --> 03:44:57,560
CONCERN WE DISCUSSED AS WELL.

5347
03:44:57,560 --> 03:45:01,280
NEXT SLIDE, PLEASE.

5348
03:45:01,280 --> 03:45:03,800
OF COURSE, NO DISCUSSION ON THE

5349
03:45:03,800 --> 03:45:04,520
ETHICS WOULD BE COMPLETE WITHOUT

5350
03:45:04,520 --> 03:45:05,680
TRYING TO UNDERSTAND THE RISK

5351
03:45:05,680 --> 03:45:07,080
BENEFITS SO WE ALSO WANTED TO

5352
03:45:07,080 --> 03:45:10,800
TALK ABOUT THE BENEFITS AND

5353
03:45:10,800 --> 03:45:12,840
UNDERSTANDING THE BENEFITS

5354
03:45:12,840 --> 03:45:14,240
RELATIVE ANY OF THE RISK THAT WE

5355
03:45:14,240 --> 03:45:15,760
HAD IDENTIFIED SO THE QUESTIONS

5356
03:45:15,760 --> 03:45:17,000
THAT WE DISCUSSED AROUND WHAT

5357
03:45:17,000 --> 03:45:19,680
WERE THE POTENTIAL BENEFITS OF

5358
03:45:19,680 --> 03:45:25,720
CONTROLLED VERSUS TIERED DATA

5359
03:45:25,720 --> 03:45:27,440
ACCESS AND HOW OPENING SHARING

5360
03:45:27,440 --> 03:45:35,560
MORE THAN CONTROLLED SHARING AND

5361
03:45:35,560 --> 03:45:36,760
THERE ISN'T EVIDENCE HOW MUCH

5362
03:45:36,760 --> 03:45:38,160
MORE THIS IS USEFUL AND HOW MUCH

5363
03:45:38,160 --> 03:45:39,680
ADDITIONAL BENEFITS ARISES FROM

5364
03:45:39,680 --> 03:45:41,400
OPEN VERSUS CONTROL SHARING.

5365
03:45:41,400 --> 03:45:43,000
SECOND WE LOOKED AROUND OPEN

5366
03:45:43,000 --> 03:45:45,040
SHARING INVOLVING FEWER

5367
03:45:45,040 --> 03:45:47,640
ADMINISTRATIVE BURDENS, TIME AND

5368
03:45:47,640 --> 03:45:48,040
COST.

5369
03:45:48,040 --> 03:45:49,600
OF COURSE THE DEGREE TO WHICH

5370
03:45:49,600 --> 03:45:53,920
IT'S TRUDY PEN DEPENDS ON THE AD

5371
03:45:53,920 --> 03:45:56,320
AND SO THAT'S AN EMPIRICAL

5372
03:45:56,320 --> 03:45:58,480
QUESTION RATHER THAN A CERTAINTY

5373
03:45:58,480 --> 03:46:00,000
AND SOME LAG TIME COULD BE

5374
03:46:00,000 --> 03:46:01,720
ACCEPTABLE GIVEN THE OVER ALL

5375
03:46:01,720 --> 03:46:03,040
DURATION AND SCIENTIFIC PROJECTS

5376
03:46:03,040 --> 03:46:04,760
SO AGAIN IT'S NOT CLEAR HOW MUCH

5377
03:46:04,760 --> 03:46:06,360
ADDITIONAL BENEFIT THERE IS AND

5378
03:46:06,360 --> 03:46:07,960
HOW MUCH ADDITIONAL BURDEN THERE

5379
03:46:07,960 --> 03:46:09,360
IS.

5380
03:46:09,360 --> 03:46:10,720
THE PUBLIC ATTITUDES SURVEY

5381
03:46:10,720 --> 03:46:12,000
SUGGESTS THAT MOST PEOPLE WHO

5382
03:46:12,000 --> 03:46:14,080
ARE WILLING TO SHARE THEIR DATA

5383
03:46:14,080 --> 03:46:17,000
SAMPLES WITH CONTROL ACCESS

5384
03:46:17,000 --> 03:46:18,640
WOULD ALSO AGREE TO DO SO UNDER

5385
03:46:18,640 --> 03:46:21,120
OPEN ACCESS AND SO THIS MAY

5386
03:46:21,120 --> 03:46:23,840
REDUCE SOME OF THE CONCERNS THAT

5387
03:46:23,840 --> 03:46:25,160
WOULD BE ARISING FROM THE

5388
03:46:25,160 --> 03:46:26,880
NEGATIVE EFFECTS OF OPEN SHARING

5389
03:46:26,880 --> 03:46:28,600
IF THEY WERE JUST AS LIKELY TO

5390
03:46:28,600 --> 03:46:31,080
SHARE IN THAT ON TEXT AND HE

5391
03:46:31,080 --> 03:46:35,960
WILAS WELL ANDTHIS WOULD SHARE D

5392
03:46:35,960 --> 03:46:37,400
AUTONOMY OF THE PARTICIPANTS.

5393
03:46:37,400 --> 03:46:41,960
NEXT SLIDE, PLEASE.

5394
03:46:41,960 --> 03:46:44,360
SO CONTINUING THIS DISCUSSION,

5395
03:46:44,360 --> 03:46:48,040
WE LOOK AT GIVEN SOCIETAL TRENDS

5396
03:46:48,040 --> 03:46:49,920
AND OUTSIDE OF NIH SUPPORTED

5397
03:46:49,920 --> 03:46:52,280
RESEARCH SOME OF THE PEOPLE IN

5398
03:46:52,280 --> 03:46:53,320
THE DISCUSSION QUESTION THE

5399
03:46:53,320 --> 03:46:55,920
DEGREE TO WHICH NIH SHOULD

5400
03:46:55,920 --> 03:46:57,840
PROTECT PARTICIPANTS' PRIVACY

5401
03:46:57,840 --> 03:47:01,080
AND BY CONTRAST PERSONAL DATA IS

5402
03:47:01,080 --> 03:47:03,120
BEING MISUSED, THIS COULD

5403
03:47:03,120 --> 03:47:07,400
INCREASE NIH'S DUTY PROTECT

5404
03:47:07,400 --> 03:47:11,800
PERSONAL DATA.

5405
03:47:11,800 --> 03:47:14,200
IT ISN'T TO SAY IT NEVER HAPPENS

5406
03:47:14,200 --> 03:47:15,800
BUT THERE ARE NOT A LOT OF WELL

5407
03:47:15,800 --> 03:47:18,000
DESCRIBED MANY ABUSE CASES OF

5408
03:47:18,000 --> 03:47:20,400
USING DATA INVOLVED IN RESEARCH

5409
03:47:20,400 --> 03:47:21,920
SETTINGS AND THERE'S A LINE WITH

5410
03:47:21,920 --> 03:47:23,520
FUNDAMENTAL PRINCIPLE OF

5411
03:47:23,520 --> 03:47:25,400
SHIFTING TOWARDS OPEN SCIENCE

5412
03:47:25,400 --> 03:47:33,360
RELATIVE TO CONTROLLED ACCESS.

5413
03:47:33,360 --> 03:47:36,680
SO THIRD, WE THEN LOOKED AT WHAT

5414
03:47:36,680 --> 03:47:38,600
STRATEGIES MIGHT MINIMIZE RISK

5415
03:47:38,600 --> 03:47:40,200
SO ASSUMING THAT WE THINK

5416
03:47:40,200 --> 03:47:41,480
THERE'S STILL SOME RISK THAT

5417
03:47:41,480 --> 03:47:43,320
WOULD ARISE FROM AN OPEN ACCESS

5418
03:47:43,320 --> 03:47:46,120
APPROACH VERSUS THE CONTROLLED

5419
03:47:46,120 --> 03:47:47,920
TIRED ACTS WHAT ARE THE WAYS WE

5420
03:47:47,920 --> 03:47:50,240
CAN MITIGATE AGAINST THOSE RISKS

5421
03:47:50,240 --> 03:47:52,960
AND WE DISCUSSED IN PARTICULAR

5422
03:47:52,960 --> 03:47:54,360
NOT TWO MAJOR APPROACHES TO

5423
03:47:54,360 --> 03:47:56,200
DOING SO ONE WOULD BE IMPROVING

5424
03:47:56,200 --> 03:47:57,400
AND INFORMED CONCEPT SO THIS

5425
03:47:57,400 --> 03:47:59,400
WOULD BE UPDATING CONSENT FORMS

5426
03:47:59,400 --> 03:48:01,400
AND THAT CAN CLARIFY THE RISK OF

5427
03:48:01,400 --> 03:48:03,160
OPEN SHARING AND PROTECTION AND

5428
03:48:03,160 --> 03:48:07,320
THE RISK OF REIDENTIFICATION

5429
03:48:07,320 --> 03:48:09,080
PARTICULARLY GIVEN AGENCY AND

5430
03:48:09,080 --> 03:48:10,200
AUTONOMY OF INDIVIDUALS GIVING

5431
03:48:10,200 --> 03:48:12,160
FULLY INFORMED CONSENT WOULD

5432
03:48:12,160 --> 03:48:14,000
MEAN MAKING SURE THE LANGUAGE IS

5433
03:48:14,000 --> 03:48:16,120
WRITTEN AROUND AN EIGHTH GRADE

5434
03:48:16,120 --> 03:48:17,400
READING LEVEL AND THE

5435
03:48:17,400 --> 03:48:18,920
SUFFICIENCY OF INFORMED CONSENT

5436
03:48:18,920 --> 03:48:22,040
EVEN IMPROVED REMAINS UNCLEAR

5437
03:48:22,040 --> 03:48:24,760
BECAUSE MANY TIMES THESE ARE

5438
03:48:24,760 --> 03:48:27,040
TREATED AS PROFORMA FORMS FOR

5439
03:48:27,040 --> 03:48:28,200
PEOPLE TO FILL OUT RATHER THAN

5440
03:48:28,200 --> 03:48:31,200
KIND OF CAREFULLY READING AS

5441
03:48:31,200 --> 03:48:32,600
IT'S UNCLEAR THE EXTEND IT WOULD

5442
03:48:32,600 --> 03:48:34,040
DISCHARGE THE DUTY BUT IT WOULD

5443
03:48:34,040 --> 03:48:36,000
AT LEAST ENSURE THAT PEOPLE WERE

5444
03:48:36,000 --> 03:48:37,240
RECEIVING THE INFORMATION IF

5445
03:48:37,240 --> 03:48:38,920
THEY CHOSE TO DIE INTO IT AND

5446
03:48:38,920 --> 03:48:49,480
SECOND IS REQUIRING OPEN ACCESS

5447
03:50:01,440 --> 03:50:05,000
ONE WAY TO ADDRESS THIS WOULD

5448
03:50:05,000 --> 03:50:06,160
EMBED BIO ETH SIS IN BUY CAM

5449
03:50:06,160 --> 03:50:07,360
PROJECTS TO ASSIST

5450
03:50:07,360 --> 03:50:09,560
CONSIDERATIONS OF THESE

5451
03:50:09,560 --> 03:50:11,280
CHALLENGES TO FLUSH OUT CONSENT

5452
03:50:11,280 --> 03:50:12,200
FORMS AND TO THINK CAREFULLY

5453
03:50:12,200 --> 03:50:14,800
ABOUT THE RISK AND BENEFITS IN A

5454
03:50:14,800 --> 03:50:22,680
CONTEXT SPECIFIC WAY THAT'S IT.

5455
03:50:22,680 --> 03:50:26,720
YOU CAN LEARN MORE AT THIS LINK.

5456
03:50:26,720 --> 03:50:29,560
AND IS GRATEFUL ACKNOWLEDGMENTS

5457
03:50:29,560 --> 03:50:35,200
TO MY CO-CHAIRS.

5458
03:50:35,200 --> 03:50:38,280
WHO HELPED TO FACILITATE THE

5459
03:50:38,280 --> 03:50:40,200
CONSULTATION AS WELL AS TO

5460
03:50:40,200 --> 03:50:41,120
PREPARE THE BACKGROUND MATERIALS

5461
03:50:41,120 --> 03:50:45,320
AND THESE PRESENTATIONS AND

5462
03:50:45,320 --> 03:50:50,440
CONSULT REQUESTERS, Dr. JOHN

5463
03:50:50,440 --> 03:50:56,440
NYE, Dr. NCCIH MER, Dr.

5464
03:50:56,440 --> 03:50:57,680
Dr. YOUNG YAW AND THE SPEAKERS

5465
03:50:57,680 --> 03:51:03,200
WHO JOINED THAT DAY.

5466
03:51:03,200 --> 03:51:04,640
THAT'S JUST A LITTLE BIT OF

5467
03:51:04,640 --> 03:51:04,920
BACKGROUND.

5468
03:51:04,920 --> 03:51:06,120
WE HAVE A FEW MINUTES FOR

5469
03:51:06,120 --> 03:51:08,000
QUESTIONS AND I KNOW ANDREA IS

5470
03:51:08,000 --> 03:51:10,320
HERE TO ANSWER ADDITIONAL

5471
03:51:10,320 --> 03:51:11,520
QUESTIONS IF I AM UNABLE TO STAY

5472
03:51:11,520 --> 03:51:13,600
WITH YOU FOR MORE QUESTIONS.

5473
03:51:13,600 --> 03:51:14,960
>> Joshua Gordon: THANK
YOU SO

5474
03:51:14,960 --> 03:51:15,280
MUCH.

5475
03:51:15,280 --> 03:51:16,600
ARE THERE QUESTIONS OR COMMENTS

5476
03:51:16,600 --> 03:51:21,160
FROM MEMBERS OF THE COUNCIL?

5477
03:51:21,160 --> 03:51:21,800
Dr. COLLINS.

5478
03:51:21,800 --> 03:51:23,920
>>THANK YOU FOR THE

5479
03:51:23,920 --> 03:51:24,680
PRESENTATION.

5480
03:51:24,680 --> 03:51:26,120
VERY T I JUST HAVE A QUESTION,

5481
03:51:26,120 --> 03:51:27,880
IS THERE A PORTFOLIO THAT IS

5482
03:51:27,880 --> 03:51:29,120
PART OF THE BRAIN INITIATIVES

5483
03:51:29,120 --> 03:51:30,520
THAT ACTUALLY STUDIES SOME OF

5484
03:51:30,520 --> 03:51:33,040
THESE ETHICS QUESTIONS AND CAN

5485
03:51:33,040 --> 03:51:34,680
GET PERSPECTIVES FROM

5486
03:51:34,680 --> 03:51:35,000
PARTICIPANTS?

5487
03:51:35,000 --> 03:51:38,480
>>THERE IS.

5488
03:51:38,480 --> 03:51:42,560
Dr. FARAMAMY OR DO YOU WANT TO

5489
03:51:42,560 --> 03:51:43,800
COMMENT HOW CLOSE THREE MIGHT

5490
03:51:43,800 --> 03:51:47,000
MATCH THESE ISSUES?

5491
03:51:47,000 --> 03:51:49,520
KHYAN LEGAL ANDREA JUMP IN ON

5492
03:51:49,520 --> 03:51:51,000
THAT TO SAY THERE'S BEEN A

5493
03:51:51,000 --> 03:51:52,800
NUMBER OF RFAs THAT ARE

5494
03:51:52,800 --> 03:51:54,640
RELATED TO NEUROETHICS AND

5495
03:51:54,640 --> 03:51:55,720
DIFFERENT FOLKS STUDYING

5496
03:51:55,720 --> 03:51:58,240
DIFFERENT ASPECTS THAT ARE BOTH

5497
03:51:58,240 --> 03:51:59,480
RELATED TO INFORMS CONSENT AND

5498
03:51:59,480 --> 03:52:01,600
RISK OF HARMS THAT ARISE FROM

5499
03:52:01,600 --> 03:52:04,880
USE OF SHARING OF DATA BUT

5500
03:52:04,880 --> 03:52:07,280
ANDREA MAY BE ABLE TO BETTER

5501
03:52:07,280 --> 03:52:08,720
ADDRESS THE PARTICULAR NOT

5502
03:52:08,720 --> 03:52:10,800
FUNDED RESEARCHERS ARE STUDYING

5503
03:52:10,800 --> 03:52:13,400
THIS ISSUE IN PARTICULAR.

5504
03:52:13,400 --> 03:52:15,800
>>YOU ANSWERED HE
QUESTION.

5505
03:52:15,800 --> 03:52:19,840
WE DON'T HAVE SPECIFIC GRANTS

5506
03:52:19,840 --> 03:52:30,320
FUNDED FOR THIS IT STRUCK ME

5507
03:52:48,280 --> 03:52:52,160
THAT THOSE WHO CURRENTLY WANT TO

5508
03:52:52,160 --> 03:52:53,200
SHARE ARE FINE WITH CONTROLLED

5509
03:52:53,200 --> 03:52:55,000
ACCESS VERSUS OPEN ACCESS.

5510
03:52:55,000 --> 03:52:57,920
BUT I WONDER ABOUT THOSE WHO WE

5511
03:52:57,920 --> 03:52:59,280
ARE, WE TALKED ABOUT POPULATIONS

5512
03:52:59,280 --> 03:53:01,400
AND WE'RE TRYING TO ENCOURAGE TO

5513
03:53:01,400 --> 03:53:03,320
COME THESE THOSE STUDIES AND

5514
03:53:03,320 --> 03:53:04,200
WHETHER OR NOT THERE'S GOING TO

5515
03:53:04,200 --> 03:53:05,880
BE SOME WORK TO EXAMINE IF THERE

5516
03:53:05,880 --> 03:53:07,760
ARE DIFFERENCES WITH THOSE

5517
03:53:07,760 --> 03:53:09,120
POPULATIONS IN TERMS OF NOT WHAT

5518
03:53:09,120 --> 03:53:11,080
THEIR PREFERENCES ARE FOR

5519
03:53:11,080 --> 03:53:13,040
CONTROL VERSUS OPEN ACCESS AND

5520
03:53:13,040 --> 03:53:16,000
I'M ALSO WONDERING IF THERE'S A

5521
03:53:16,000 --> 03:53:17,120
HYPE OF POSSIBILITY THAT IS

5522
03:53:17,120 --> 03:53:22,000
OPTION THAT IS POSSIBLE.

5523
03:53:22,000 --> 03:53:22,360
>>

5524
03:53:22,360 --> 03:53:23,560
>>PLEASE, GO AHEAD.

5525
03:53:23,560 --> 03:53:25,000
>>YOU ARE SHORT ON TIME.

5526
03:53:25,000 --> 03:53:26,920
>>I WAS JUST GOING TO
SAY, IT'S

5527
03:53:26,920 --> 03:53:29,200
INTERESTING BECAUSE THERE'S BEEN

5528
03:53:29,200 --> 03:53:31,120
A GOOD BIT OF RESEARCH YOU DONE

5529
03:53:31,120 --> 03:53:33,000
ON WILLINGNESS TO SHARE WITH

5530
03:53:33,000 --> 03:53:34,360
RESEARCHERS ACROSS DIFFERENT

5531
03:53:34,360 --> 03:53:37,120
COMMUNITIES AND THE NUMBERS STAY

5532
03:53:37,120 --> 03:53:41,680
PRETTY CONSTANT ACROSS DIFFERENT

5533
03:53:41,680 --> 03:53:50,240
COMMUNITIES AND AND OF THOSE

5534
03:53:50,240 --> 03:53:51,120
COMMUNITIES WHO ARE GENERALLY

5535
03:53:51,120 --> 03:53:53,080
INVOLVED YOU ARE LOOKING AT A

5536
03:53:53,080 --> 03:53:54,560
PRETTY CONSISTENT WILLINGNESS TO

5537
03:53:54,560 --> 03:53:57,160
SHARE AND IT BREAKS DOWN TO

5538
03:53:57,160 --> 03:53:58,760
USUALLY 80/20 AND DEPENDING ON

5539
03:53:58,760 --> 03:54:01,600
WHETHER IT'S AN OPT-IN OR

5540
03:54:01,600 --> 03:54:02,000
OPT-OUT APPROACH.

5541
03:54:02,000 --> 03:54:03,400
ONE OF THE PRESENTATIONS WE HAVE

5542
03:54:03,400 --> 03:54:04,680
FROM Dr. CLAYTON SHOWED THERE

5543
03:54:04,680 --> 03:54:06,280
WAS A SIGNIFICANT WILLINGNESS BY

5544
03:54:06,280 --> 03:54:07,800
PEOPLE TO SHARE THE CONTEXT

5545
03:54:07,800 --> 03:54:10,920
ALONG AS THEY WERE ADEQUATELY

5546
03:54:10,920 --> 03:54:12,000
GIVEN INFORMATION ABOUT THE RISK

5547
03:54:12,000 --> 03:54:16,960
AND BENEFITS OF DOING SO.

5548
03:54:16,960 --> 03:54:19,000
>>WE ACTUALLY DO HAVE
SOME

5549
03:54:19,000 --> 03:54:21,640
STUDIES THAT ARE ON THAT TOPIC

5550
03:54:21,640 --> 03:54:22,720
SPECIFICALLY THAT WE'RE

5551
03:54:22,720 --> 03:54:24,080
SUPPORTING AND WE DON'T HAVE

5552
03:54:24,080 --> 03:54:25,480
DATA YET BUT WE HOPE TO HAVE IT

5553
03:54:25,480 --> 03:54:28,440
SOON AND I THINK SOME OF OUR

5554
03:54:28,440 --> 03:54:31,320
FOCUS HAS BEEN ON ENGAGEMENT AND

5555
03:54:31,320 --> 03:54:35,160
PROMOTING UNDERSTANDING.

5556
03:54:35,160 --> 03:54:36,920
>>TED --

5557
03:54:36,920 --> 03:54:37,600
>>A COMMENT.

5558
03:54:37,600 --> 03:54:39,920
THANK YOU FOR THE PRESENTATION.

5559
03:54:39,920 --> 03:54:41,840
AND I WANTED TO RELAY ONE THING

5560
03:54:41,840 --> 03:54:45,080
THAT JOHN NYE PUT IN THE WEBINAR

5561
03:54:45,080 --> 03:54:46,720
CHAT THAT THERE ARE BIO EMPHASIS

5562
03:54:46,720 --> 03:54:48,480
EMBEDDED IN THE BUY CAM PROJECTS

5563
03:54:48,480 --> 03:54:52,400
AND IT'S WHAT I WANTED TO POINT

5564
03:54:52,400 --> 03:54:54,400
OUT THAT IS A TERRIFIC MODEL AND

5565
03:54:54,400 --> 03:54:57,480
THE IDEA OF HAVING BIO ETH A SIS

5566
03:54:57,480 --> 03:54:59,680
AS PART OF OUR LARGER PROJECTS

5567
03:54:59,680 --> 03:55:01,400
IS SOMETHING THAT I FIRST

5568
03:55:01,400 --> 03:55:02,400
ENCOUNTERED WITH THE BRAIN

5569
03:55:02,400 --> 03:55:06,640
INITIATIVE AN I'M THE

5570
03:55:06,640 --> 03:55:07,520
REPRESENTATIVE OF THIS COUNCIL

5571
03:55:07,520 --> 03:55:08,600
ON THE MULTI COUNCIL WORKING

5572
03:55:08,600 --> 03:55:10,200
GROUP AND I THINK IT'S A

5573
03:55:10,200 --> 03:55:11,600
TREMENDOUS IDEA AND I THINK THAT

5574
03:55:11,600 --> 03:55:13,200
THAT IS TO ME ONE OF THE MOST

5575
03:55:13,200 --> 03:55:14,840
PORT AM THINGS TO THINK ABOUT AS

5576
03:55:14,840 --> 03:55:16,800
A RESPONSE TO THIS AND WE MAY

5577
03:55:16,800 --> 03:55:18,240
WANT TO THINK ABOUT IT MORE

5578
03:55:18,240 --> 03:55:20,160
BROADLY AS WE THINK ABOUT OUR

5579
03:55:20,160 --> 03:55:22,680
LARGER CENTER INITIATIVES

5580
03:55:22,680 --> 03:55:24,400
BECAUSE I THINK THAT THE BIO ETH

5581
03:55:24,400 --> 03:55:26,680
SIS HAVE A LOT TO TEACH US AND

5582
03:55:26,680 --> 03:55:27,920
THE VERY NITTY GRITTY DISCUSSION

5583
03:55:27,920 --> 03:55:29,240
I HAD WAS ABOUT THE DIFFERENCE

5584
03:55:29,240 --> 03:55:30,680
OF HAVING A BRAIN SAMPLE AND

5585
03:55:30,680 --> 03:55:31,840
WHETHER YOU ARE GOING TO DO

5586
03:55:31,840 --> 03:55:35,360
SINGLE NUCLEAR RNA SEEK OR MULTI

5587
03:55:35,360 --> 03:55:36,920
OMIC WHERE YOU SEQUENCE THE

5588
03:55:36,920 --> 03:55:38,720
WHOLE GENOME.

5589
03:55:38,720 --> 03:55:40,720
YOU HAVE AN IRB AND YOU CAN HAVE

5590
03:55:40,720 --> 03:55:49,240
A SYMBOL BUT DON'T SEQUENCE MY

5591
03:55:49,240 --> 03:55:49,800
GENOME.

5592
03:55:49,800 --> 03:55:53,680
IT COMES IN UP BRAIN INITIATIVE

5593
03:55:53,680 --> 03:55:54,560
WHERE OPPORTUNITIES IS THE MORE

5594
03:55:54,560 --> 03:55:58,400
AND MORE PATIENTS THAT ARE IN

5595
03:55:58,400 --> 03:56:01,880
NEURO SURGICAL STUDIES AND BRAIN

5596
03:56:01,880 --> 03:56:03,200
COMPUTER INTERFACE STUDIES AND

5597
03:56:03,200 --> 03:56:05,160
HOW THOSE WORK WHICH IS ONE AREA

5598
03:56:05,160 --> 03:56:06,120
WHERE THEY'RE HEAVY INVOLVED

5599
03:56:06,120 --> 03:56:07,600
WHICH IS TREMENDOUSLY IMPORTANT

5600
03:56:07,600 --> 03:56:09,840
SO I THINK ONE THING FOR US TO

5601
03:56:09,840 --> 03:56:12,960
THINK ABOUT AT NIMH IS

5602
03:56:12,960 --> 03:56:15,120
INCORPORATING NOT NEUROETHICS IN

5603
03:56:15,120 --> 03:56:16,760
WHAT WE DO AND WHAT WE THINK

5604
03:56:16,760 --> 03:56:19,800
ABOUT MORE.

5605
03:56:19,800 --> 03:56:20,240
THANK YOU.

5606
03:56:20,240 --> 03:56:22,720
>>I'M GOING TO SAY HEAR
HEAR TO

5607
03:56:22,720 --> 03:56:23,440
THAT ONE.

5608
03:56:23,440 --> 03:56:26,280
I WILL SAY THAT WHAT YOU SAID IS

5609
03:56:26,280 --> 03:56:28,200
IMPORTANT AND JOHN'S POINT HERE

5610
03:56:28,200 --> 03:56:30,080
ABOUT EMBEDDING IS THE IMPORTANT

5611
03:56:30,080 --> 03:56:31,880
WHICH IS, THE MORE IT'S PART OF

5612
03:56:31,880 --> 03:56:37,280
AN ONGOING DIALOGUE, THE MORE

5613
03:56:37,280 --> 03:56:38,320
THERE'S A ROLE AND MITIGATESSED

5614
03:56:38,320 --> 03:56:47,200
RIT'S MOREREACTIVE AND AFTER THR

5615
03:56:47,200 --> 03:56:49,800
IT'S HARDER TO HAVE AN

5616
03:56:49,800 --> 03:56:50,640
INTEGRATED AND THE PROGRESS OF

5617
03:56:50,640 --> 03:57:01,080
THE STUDY ITSELF ORS WHERE

5618
03:57:05,480 --> 03:57:06,760
PEOPLE ARE OFF ON AN ISLAND

5619
03:57:06,760 --> 03:57:08,160
DOING THEIR OWN THING RATHER

5620
03:57:08,160 --> 03:57:10,240
THAN INTEGRATING IT INTO THE

5621
03:57:10,240 --> 03:57:11,000
RESEARCH PROCESS ITSELF.

5622
03:57:11,000 --> 03:57:12,680
>>THANK YOU, VERY MUCH.

5623
03:57:12,680 --> 03:57:14,360
APPRECIATE IT.

5624
03:57:14,360 --> 03:57:16,360
AND HOPEFULLY JOHN AND ANDREA

5625
03:57:16,360 --> 03:57:18,840
YOU GOT ENOUGH TO THINK ABOUT OF

5626
03:57:18,840 --> 03:57:20,920
HOW YOU WILL MOVE FORWARD AND

5627
03:57:20,920 --> 03:57:22,600
WITH THAT WE'LL MOVE INTO THE

5628
03:57:22,600 --> 03:57:24,560
NEXT SEGMENT OF OUR MEETING

5629
03:57:24,560 --> 03:57:28,040
WHICH IS THE PUBLIC COMMENT

5630
03:57:28,040 --> 03:57:28,400
SECTION.

5631
03:57:28,400 --> 03:57:33,120
VERY PLEASED TO RETHE PUBLIC AND

5632
03:57:33,120 --> 03:57:37,600
I BELIEVE WE HAVE ONE PRIOR

5633
03:57:37,600 --> 03:57:39,080
REGISTRANT WHO WOULD LIKE TO

5634
03:57:39,080 --> 03:57:42,120
GIVE ORAL COMMENT.

5635
03:57:42,120 --> 03:57:43,360
RESTRICT YOUR COMMENTS TO THREE

5636
03:57:43,360 --> 03:57:44,440
MINUTES WHICH I WILL TIME TO

5637
03:57:44,440 --> 03:57:47,360
MAKE SURE THAT WE STICK TO IT

5638
03:57:47,360 --> 03:57:49,680
AND SO I INVITE FIRST THE PRIOR

5639
03:57:49,680 --> 03:57:53,400
REGISTRANT TO COME AND THIS IS

5640
03:57:53,400 --> 03:57:55,960
Dr. OKACHNGA AND THE PEOPLE OF

5641
03:57:55,960 --> 03:57:57,200
ETHICAL TREATMENT OF ANIMALS AND

5642
03:57:57,200 --> 03:57:58,600
I BELIEVE WE HAVE A MICROPHONE

5643
03:57:58,600 --> 03:58:02,160
SET UP FOR YOU.

5644
03:58:02,160 --> 03:58:06,080
>>

5645
03:58:06,080 --> 03:58:07,400
>>GOOD AFTERNOON, ALL.

5646
03:58:07,400 --> 03:58:13,240
MY NAME IS Dr. AKLCANA AND I

5647
03:58:13,240 --> 03:58:15,160
SERVE AS PRICE HAVE OF THE PITA

5648
03:58:15,160 --> 03:58:16,840
LABORATORY AND CASES AND THE

5649
03:58:16,840 --> 03:58:27,400
TREATMENT OF ANIMALS AND CARRIED

5650
03:58:28,560 --> 03:58:31,080
AT THE INTRAMURAL RESEARCH

5651
03:58:31,080 --> 03:58:33,760
PROGRAM AND IN THE LAB, MACAQUES

5652
03:58:33,760 --> 03:58:37,400
ARE SUBJECTED TO NUMEROUS AND

5653
03:58:37,400 --> 03:58:39,400
INVASIVE SURGERIES TO HAVE

5654
03:58:39,400 --> 03:58:41,880
TOXINS INJECTED INTO THEIR

5655
03:58:41,880 --> 03:58:43,680
BRAINS AND HEAD POSTS AND

5656
03:58:43,680 --> 03:58:44,920
CHAMBERS SCREWED TO THEIR

5657
03:58:44,920 --> 03:58:46,440
SKULLS.

5658
03:58:46,440 --> 03:58:49,000
THESE MONKEYS ARE RESTRAINED FOR

5659
03:58:49,000 --> 03:58:51,360
HOURS AT A TIME DEPRIVED OF FOOD

5660
03:58:51,360 --> 03:58:53,520
AND WATER SO THEY WILL COOPERATE

5661
03:58:53,520 --> 03:58:56,800
WHEN SUBJECTED TO BEHAVIORAL

5662
03:58:56,800 --> 03:58:58,880
TRIALS AND OFTEN FOR THEM IS

5663
03:58:58,880 --> 03:59:00,440
SOCIAL ISOLATION FOR YEARS

5664
03:59:00,440 --> 03:59:03,520
BEFORE BEING KILLED.

5665
03:59:03,520 --> 03:59:04,640
THESE EXPERIMENTS WHICH HAVE

5666
03:59:04,640 --> 03:59:07,760
BEEN GOING ON FOR FOUR DECADES,

5667
03:59:07,760 --> 03:59:10,080
AND HAVE COST TAXPAYERS

5668
03:59:10,080 --> 03:59:11,320
$50 MILLION, HAVE FAILED TO

5669
03:59:11,320 --> 03:59:12,600
PROVIDE DATA MEANINGFUL ENOUGH

5670
03:59:12,600 --> 03:59:15,520
TO IMPROVE HUMAN MENTAL HEALTH.

5671
03:59:15,520 --> 03:59:19,280
AS A CONSIDERABLE HARM INFLICTED

5672
03:59:19,280 --> 03:59:24,240
ON NON CONSENTING SEN TEE ANT

5673
03:59:24,240 --> 03:59:25,920
MONKEYS ARE EVIDENCE IN

5674
03:59:25,920 --> 03:59:28,520
DOCUMENTS MAINTAINED BY A LAB

5675
03:59:28,520 --> 03:59:31,160
WHICH WERE OBTAINED OF PETA

5676
03:59:31,160 --> 03:59:33,920
THROUGH FREEDOM OF INFORMATION

5677
03:59:33,920 --> 03:59:34,160
REQUEST.

5678
03:59:34,160 --> 03:59:35,560
I'LL SHARE THE STORY OF JUST ONE

5679
03:59:35,560 --> 03:59:36,360
MONKEY.

5680
03:59:36,360 --> 03:59:38,080
SAM SMITH, AS LAB STAFF NAMED

5681
03:59:38,080 --> 03:59:40,720
HIM WAS BORN AT A SOUTH CAROLINA

5682
03:59:40,720 --> 03:59:43,600
BASED MONKEY BREEDER AND DEALER

5683
03:59:43,600 --> 03:59:44,760
CALLED ALPHA GENESIS.

5684
03:59:44,760 --> 03:59:47,120
AND BROUGHT TO NIH WHEN HE WAS

5685
03:59:47,120 --> 03:59:47,800
TWO.

5686
03:59:47,800 --> 03:59:49,120
HE WAS NEARLY FIVE WHEN HE WAS

5687
03:59:49,120 --> 03:59:51,920
PLACED IN THE INTRAMURAL LAB AT

5688
03:59:51,920 --> 03:59:54,240
A NIMH.

5689
03:59:54,240 --> 03:59:56,040
SHORTLY THERE A. EXPERIMENTERS

5690
03:59:56,040 --> 03:59:58,920
CUT INTO SAM'S SKULL AND

5691
03:59:58,920 --> 04:00:02,440
INJECTED EXCITE OWE TOXINS INTO

5692
04:00:02,440 --> 04:00:04,560
HIS MIG DA LA CAUSING PERMANENT

5693
04:00:04,560 --> 04:00:05,320
BRAIN DAMAGE.

5694
04:00:05,320 --> 04:00:08,160
TWO WEEKS LATER HE WAS SUBJECTED

5695
04:00:08,160 --> 04:00:10,360
TO ANOTHER SURGERY THIS ONE TO

5696
04:00:10,360 --> 04:00:13,720
REMOVE A HEMATOMA FROM UNDER HIS

5697
04:00:13,720 --> 04:00:15,840
SKULL AFTER A BLOOD VESSEL WAS

5698
04:00:15,840 --> 04:00:17,240
CUT DURING THE PREVIOUS SURGERY.

5699
04:00:17,240 --> 04:00:19,880
A FEW WEEKS AFTER THAT.

5700
04:00:19,880 --> 04:00:22,280
SAM SMITH'S CORTEX WAS LESIONED

5701
04:00:22,280 --> 04:00:27,400
THROUGH ASPIRATION.

5702
04:00:27,400 --> 04:00:29,120
SAM SMITH HAS BEEN CAGED ALONE

5703
04:00:29,120 --> 04:00:31,880
SINCE JULY OF 2009.

5704
04:00:31,880 --> 04:00:34,160
NOTATIONS AND SAM SMITH'S

5705
04:00:34,160 --> 04:00:36,880
RECORDS INDICATE THAT HE ENGAGES

5706
04:00:36,880 --> 04:00:39,480
IN STEREO TYPING AND CIRCLING IN

5707
04:00:39,480 --> 04:00:41,800
HIS CAGE AND ROCKING BACK AND

5708
04:00:41,800 --> 04:00:43,520
FOURTH, HIS PSYCHOLOGICAL

5709
04:00:43,520 --> 04:00:45,400
DISTRESS IS EVIDENT IN HIS

5710
04:00:45,400 --> 04:00:51,320
EXTENSIVE HAIR LOSS.

5711
04:00:51,320 --> 04:00:52,240
UNABLE TO CONTROL ANYTHING IN

5712
04:00:52,240 --> 04:00:55,480
THEIR LIVES, MONKEYS IN LABS

5713
04:00:55,480 --> 04:00:58,160
PULL OUT THEIR OWN HAIR.

5714
04:00:58,160 --> 04:01:01,480
IT'S ONE THING THEY CAN CONTROL.

5715
04:01:01,480 --> 04:01:03,920
SAM SMITH HAS BEFORE STARVED,

5716
04:01:03,920 --> 04:01:04,520
SEDATED, STRAPPED INTO

5717
04:01:04,520 --> 04:01:07,680
RESTRAINTS AND FORCED TO ENDURE

5718
04:01:07,680 --> 04:01:08,560
PAINFUL PROCEDURES.

5719
04:01:08,560 --> 04:01:11,720
HE IS JUST ONE OF HUNDREDS OF

5720
04:01:11,720 --> 04:01:13,280
MONKEYS WHO HAVE BEEN HARMED IN

5721
04:01:13,280 --> 04:01:15,920
THIS INTRAMURAL LAB.

5722
04:01:15,920 --> 04:01:18,080
TO OUR KNOWLEDGE, SAM SMITH IS

5723
04:01:18,080 --> 04:01:18,560
STILL ALIVE.

5724
04:01:18,560 --> 04:01:23,440
AND IS ONE OF 91 RECESS MACAQUES

5725
04:01:23,440 --> 04:01:25,880
CURRENTLY HELD IN THIS LAB.

5726
04:01:25,880 --> 04:01:28,640
IS THAT THREE MINUTES?

5727
04:01:28,640 --> 04:01:30,680
WELL, I BELIEVE THE FULL

5728
04:01:30,680 --> 04:01:32,280
TRANSCRIPT OF MY COMMENTS ARE IN

5729
04:01:32,280 --> 04:01:32,640
YOUR RECORDS.

5730
04:01:32,640 --> 04:01:34,240
THANK YOU, VERY MUCH.

5731
04:01:34,240 --> 04:01:35,520
>>THAT'S RIGHT.

5732
04:01:35,520 --> 04:01:36,280
THANK YOU.

5733
04:01:36,280 --> 04:01:36,800
FULL COMMENTS ARE IN THE

5734
04:01:36,800 --> 04:01:37,040
RECORDS.

5735
04:01:37,040 --> 04:01:38,440
THANK YOU, VERY MUCH.

5736
04:01:38,440 --> 04:01:39,080
>> Joshua Gordon: ALL
MEMBERS

5737
04:01:39,080 --> 04:01:40,360
OF OUR COUNCIL HAVE RECEIVED

5738
04:01:40,360 --> 04:01:40,800
THEM.

5739
04:01:40,800 --> 04:01:42,320
APPRECIATE YOU COMING TO US

5740
04:01:42,320 --> 04:01:42,760
TODAY.

5741
04:01:42,760 --> 04:01:45,000
ARE THERE OTHER MEMBERS OF

5742
04:01:45,000 --> 04:01:46,320
PUBLIC MEMBERS WHO WOULD LIKE TO

5743
04:01:46,320 --> 04:01:50,800
MAKE A COMMENT?

5744
04:01:50,800 --> 04:01:51,240
-THANK YOU.

5745
04:01:51,240 --> 04:01:52,600
ARE THERE ANY QUESTIONS OR

5746
04:01:52,600 --> 04:01:56,360
COMMENTS FROM THE COUNCIL?

5747
04:01:56,360 --> 04:01:57,160
ALL RIGHT.

5748
04:01:57,160 --> 04:01:58,800
WELL, WITH NO FURTHER ADIEU, I

5749
04:01:58,800 --> 04:02:01,480
THINK WE ACTUALLY ADJOURN ON

5750
04:02:01,480 --> 04:02:02,280
TIME.

5751
04:02:02,280 --> 04:02:03,800
APPRECIATE EVERYONE'S WORK TODAY

5752
04:02:03,800 --> 04:02:05,480
AND I ESPECIALLY APPRECIATE THE

5753
04:02:05,480 --> 04:02:06,880
WORK THAT WE WILL DO TOMORROW

5754
04:02:06,880 --> 04:02:08,880
DURING THE CLOSED SESSION AND

5755
04:02:08,880 --> 04:02:10,480
WITH THAT, I CONCLUDE THE OPEN

5756
04:02:10,480 --> 04:02:13,120
SESSION OF THIS COUNCIL.

5757
04:02:13,120 --> 04:02:23,520
I GET TO BIND THE GAVEL.