1 00:00:05,608 --> 00:00:07,944 >> GOOD MORNING, WELCOME, 2 00:00:07,944 --> 00:00:10,179 COUNCIL MEMBERS AND GUESTS TO 3 00:00:10,179 --> 00:00:17,019 THE 235th MEETING OF THE 4 00:00:17,019 --> 00:00:18,221 NATIONAL ADVISORY COUNCIL, 5 00:00:18,221 --> 00:00:20,623 VIRTUALLY VIA ZOOM WITH 6 00:00:20,623 --> 00:00:21,524 ACCOMPANYING NIH VIDEOCAST FOR 7 00:00:21,524 --> 00:00:22,625 VIEWING BY THE PUBLIC. 8 00:00:22,625 --> 00:00:24,360 WE'LL NOT BE TAKING QUESTIONS OR 9 00:00:24,360 --> 00:00:27,330 COMMENTS FROM THE PUBLIC DURING 10 00:00:27,330 --> 00:00:29,165 THE LIVE VIDEOCAST, BUT WILL 11 00:00:29,165 --> 00:00:32,235 ACCEPT QUESTIONS OR COMMENTS 12 00:00:32,235 --> 00:00:34,337 UNTIL FEBRUARY 8, VIA NIDCR 13 00:00:34,337 --> 00:00:35,538 E-MAIL ADDRESS THAT I WILL POST 14 00:00:35,538 --> 00:00:38,608 AT THE END OF THE OPEN SESSION. 15 00:00:38,608 --> 00:00:42,645 WE ASK THAT COUNCIL MEMBERS AND 16 00:00:42,645 --> 00:00:44,313 NIDCR STAFF MAKE SURE 17 00:00:44,313 --> 00:00:47,116 MICROPHONES ARE ON MUTE AND 18 00:00:47,116 --> 00:00:48,684 VIDEO CAMERAS ARE OFF UNLESS 19 00:00:48,684 --> 00:00:50,553 YOU'RE SPEAKING. 20 00:00:50,553 --> 00:00:52,154 PLEASE STATE YOUR NAME WHEN YOU 21 00:00:52,154 --> 00:00:54,357 SPEAK SO WE CAN IDENTIFY WHO IS 22 00:00:54,357 --> 00:00:56,359 SPEAKING AND CAN ENSURE ACCURACY 23 00:00:56,359 --> 00:00:58,227 OF OUR MEETING RECORDS. 24 00:00:58,227 --> 00:01:03,132 IF ANYONE PARTICIPATING IN THE 25 00:01:03,132 --> 00:01:04,767 ZOOM MEETING NEEDS TECHNICAL 26 00:01:04,767 --> 00:01:06,202 ASSISTANCE, THE I.T. SUPPORT 27 00:01:06,202 --> 00:01:08,838 TEAM WILL BE AVAILABLE TO ASSIST 28 00:01:08,838 --> 00:01:09,038 YOU. 29 00:01:09,038 --> 00:01:10,239 THEIR CONTACT INFORMATION WILL 30 00:01:10,239 --> 00:01:13,309 BE POSTED IN THE CHAT. 31 00:01:13,309 --> 00:01:16,178 THE FIRST ITEM OF BUSINESS IS 32 00:01:16,178 --> 00:01:18,147 APPROVAL OF MINUTES OF THE 33 00:01:18,147 --> 00:01:19,815 PREVIOUS MEETING, THE MINUTES 34 00:01:19,815 --> 00:01:21,550 FROM THE SEPTEMBER 2023 MEETING 35 00:01:21,550 --> 00:01:26,656 WERE MADE AVAILABLE TO COUNCIL 36 00:01:26,656 --> 00:01:28,190 MEMBERS FOR REVIEW, ARE THERE 37 00:01:28,190 --> 00:01:34,797 COMMENTS OR DIRECTION ON THE 38 00:01:34,797 --> 00:01:35,131 MINUTES? 39 00:01:35,131 --> 00:01:36,899 IF NO COMMENTS WOULD A MEMBER OF 40 00:01:36,899 --> 00:01:40,603 COUNCIL MAKE A MOTION TO APPROVE 41 00:01:40,603 --> 00:01:42,305 THE MINUTES? 42 00:01:42,305 --> 00:01:43,339 >> SO MOVED. 43 00:01:43,339 --> 00:01:46,942 >> SECOND. 44 00:01:46,942 --> 00:01:48,010 EBETINO. 45 00:01:48,010 --> 00:01:51,881 >> DR. NOR AND EBETINO. 46 00:01:51,881 --> 00:01:53,182 ALL IN FAVOR? 47 00:01:53,182 --> 00:01:54,950 >> AYE. 48 00:01:54,950 --> 00:01:55,518 >> AYE. 49 00:01:55,518 --> 00:02:02,024 >> ANY OPPOSED? 50 00:02:02,024 --> 00:02:02,925 NO? 51 00:02:02,925 --> 00:02:03,693 OKAY. 52 00:02:03,693 --> 00:02:04,794 SECOND ITEM OF BUSINESS, EACH 53 00:02:04,794 --> 00:02:09,632 YEAR AT THE JANUARY MEETING 54 00:02:09,632 --> 00:02:13,936 COUNCIL WE REVIEW AND APPROVE 55 00:02:13,936 --> 00:02:14,570 ADVISORY COUNCIL OPERATING 56 00:02:14,570 --> 00:02:16,205 PROCEDURES AND WE HAVE AN 57 00:02:16,205 --> 00:02:17,740 OPPORTUNITY TO MAKE 58 00:02:17,740 --> 00:02:21,243 RECOMMENDATIONS FOR REVISIONS 59 00:02:21,243 --> 00:02:23,979 WHEN APPROPRIATE. 60 00:02:23,979 --> 00:02:25,748 THIS YEAR WE'RE RECOMMENDING 61 00:02:25,748 --> 00:02:28,150 MODIFICATION OF IMPLEMENTATION 62 00:02:28,150 --> 00:02:31,120 OF SPECIAL COUNCIL REVIEW, SCR 63 00:02:31,120 --> 00:02:32,021 POLICY. 64 00:02:32,021 --> 00:02:35,424 THIS POLICY REQUIRES SPECIAL 65 00:02:35,424 --> 00:02:36,959 CONSIDERATION, ADDITIONAL REVIEW 66 00:02:36,959 --> 00:02:40,429 OF GRANTS AND COOPERATIVE 67 00:02:40,429 --> 00:02:42,865 AGREEMENT APPLICATIONS FROM 68 00:02:42,865 --> 00:02:44,567 PRINCIPAL INVESTIGATORS WHO 69 00:02:44,567 --> 00:02:46,602 RECEIVE MORE THAN $2 MILLION IN 70 00:02:46,602 --> 00:02:48,771 TOTAL COSTS INCLUDING DIRECT AND 71 00:02:48,771 --> 00:02:52,808 INDIRECT COSTS PER YEAR FOR ALL 72 00:02:52,808 --> 00:02:54,910 ACTIVE NIH AWARDS. 73 00:02:54,910 --> 00:02:57,413 THE NIDCR COUNCIL OPERATING 74 00:02:57,413 --> 00:03:03,819 PROCEDURES CURRENTLY STATES THAT 75 00:03:03,819 --> 00:03:05,154 COUNCIL PROVIDES SECONDARY 76 00:03:05,154 --> 00:03:07,223 REVIEW FOR ELIGIBLE FOR FUNDING 77 00:03:07,223 --> 00:03:09,492 APPLICATIONS FROM INVESTIGATORS 78 00:03:09,492 --> 00:03:10,593 WITH GREATER THAN $2 MILLION 79 00:03:10,593 --> 00:03:14,296 TOTAL COST IN RESEARCH SUPPORT 80 00:03:14,296 --> 00:03:14,964 FROM NIH. 81 00:03:14,964 --> 00:03:20,302 FOR NIDCR TO MANAGE RESOURCES 82 00:03:20,302 --> 00:03:21,404 MORE EFFECTIVELY WE'RE 83 00:03:21,404 --> 00:03:22,738 RECOMMENDING TWO CHANGES TO 84 00:03:22,738 --> 00:03:24,373 SPECIAL REVIEW. 85 00:03:24,373 --> 00:03:27,443 FIRST IS TO CHANGE TO ELIGIBLE 86 00:03:27,443 --> 00:03:29,845 FOR THIS POLICY WOULD APPLY TO 87 00:03:29,845 --> 00:03:31,280 ELIGIBLE FOR FUNDING 88 00:03:31,280 --> 00:03:32,915 APPLICATIONS FROM INVESTIGATORS 89 00:03:32,915 --> 00:03:33,916 WITH GREATER THAN $2 MILLION 90 00:03:33,916 --> 00:03:37,286 TOTAL COST IN RESEARCH SUPPORT 91 00:03:37,286 --> 00:03:40,122 FROM NIH, INCLUDING THOSE 92 00:03:40,122 --> 00:03:43,392 APPLICATIONS THAT ARE PENDING 93 00:03:43,392 --> 00:03:45,394 REVIEW, SO PENDING -- INCLUDING 94 00:03:45,394 --> 00:03:46,595 PENDING APPLICATIONS. 95 00:03:46,595 --> 00:03:49,698 THE SECOND CHANGE ELIGIBLE FOR 96 00:03:49,698 --> 00:03:52,301 FUNDING APPLICATIONS FOR 97 00:03:52,301 --> 00:03:52,935 MULTIPLE P.I. APPLICATIONS WHEN 98 00:03:52,935 --> 00:03:55,371 ANY P.I. HAS GREATER THAN $2 99 00:03:55,371 --> 00:03:58,040 MILLION TOTAL COST IN RESEARCH 100 00:03:58,040 --> 00:03:58,974 SUPPORT FROM NIH. 101 00:03:58,974 --> 00:04:01,377 SO THOSE ARE THE TWO CHANGES 102 00:04:01,377 --> 00:04:03,479 THAT WE'RE RECOMMENDING IN THE 103 00:04:03,479 --> 00:04:05,014 COUNCIL OPERATING PROCEDURES FOR 104 00:04:05,014 --> 00:04:06,215 THE SPECIAL COUNCIL REVIEW 105 00:04:06,215 --> 00:04:06,782 POLICY. 106 00:04:06,782 --> 00:04:08,617 ARE THERE ANY COMMENTS OR 107 00:04:08,617 --> 00:04:15,024 QUESTIONS ABOUT THIS CHANGE IN 108 00:04:15,024 --> 00:04:16,525 NIDCR POLICY? 109 00:04:16,525 --> 00:04:16,725 OKAY. 110 00:04:16,725 --> 00:04:19,028 IF NOT, WOULD SOMEONE LIKE TO 111 00:04:19,028 --> 00:04:24,500 MAKE A MOTION TO APPROVE THE 112 00:04:24,500 --> 00:04:25,267 MODIFICATION? 113 00:04:25,267 --> 00:04:25,468 OKAY. 114 00:04:25,468 --> 00:04:35,911 AND ANYONE LIKE TO SECOND? 115 00:04:36,111 --> 00:04:39,515 JOSE 116 00:04:39,515 --> 00:04:40,816 SECOND BY JACQUES. 117 00:04:40,816 --> 00:04:41,851 ALL IN FAVOR? 118 00:04:41,851 --> 00:04:42,117 >> AYE. 119 00:04:42,117 --> 00:04:44,353 >> ANYONE OPPOSED? 120 00:04:44,353 --> 00:04:45,721 ALL RIGHT. 121 00:04:45,721 --> 00:04:45,988 THANK YOU. 122 00:04:45,988 --> 00:04:48,491 AND NOW I'LL TURN IT OVER TO DR. 123 00:04:48,491 --> 00:04:50,259 RENA D'SOUZA. 124 00:04:50,259 --> 00:04:52,294 FOR HER WELCOME AND 125 00:04:52,294 --> 00:04:52,628 PRESENTATION. 126 00:04:52,628 --> 00:04:54,630 >> LYNN, WOULD YOU GET OUT OF 127 00:04:54,630 --> 00:04:55,498 YOUR SHARE SCREEN PLEASE? 128 00:04:55,498 --> 00:05:00,503 THANK YOU VERY MUCH FOR THAT 129 00:05:00,503 --> 00:05:01,203 INTRODUCTION. 130 00:05:01,203 --> 00:05:01,504 GREAT. 131 00:05:01,504 --> 00:05:04,273 I WANT TO SAY HELLO TO EVERYONE. 132 00:05:04,273 --> 00:05:08,210 THANK YOU FOR BEING PRESENT. 133 00:05:08,210 --> 00:05:11,847 AND I CAN'T HELP BUT WISH FOR 134 00:05:11,847 --> 00:05:14,450 YOU A PEACEFUL, HEALTHY, 135 00:05:14,450 --> 00:05:14,817 PRODUCTIVE YEAR. 136 00:05:14,817 --> 00:05:17,620 WE HAVE SO MUCH GOING ON IN OUR 137 00:05:17,620 --> 00:05:18,721 WORLD TODAY. 138 00:05:18,721 --> 00:05:20,589 THINGS ARE SWIRLING AROUND IN 139 00:05:20,589 --> 00:05:24,793 CHAOS, BUT I THINK FOR ALL OF US 140 00:05:24,793 --> 00:05:28,697 ESPECIALLY AT NIDCR WE WILL STAY 141 00:05:28,697 --> 00:05:31,634 TRUE TO COURSE AND FULFILL OUR 142 00:05:31,634 --> 00:05:34,470 MISSION THE BEST WAY WE KNOW 143 00:05:34,470 --> 00:05:34,637 HOW. 144 00:05:34,637 --> 00:05:35,905 IMAGINE SEPTEMBER COUNCIL LAST 145 00:05:35,905 --> 00:05:37,006 YEAR, HOW INTERACTIVE THAT WAS 146 00:05:37,006 --> 00:05:39,308 BECAUSE WE WERE IN PERSON. 147 00:05:39,308 --> 00:05:40,843 THE VIRTUAL SETTING IS A GREAT 148 00:05:40,843 --> 00:05:42,611 ADVANTAGE AS WELL BECAUSE PEOPLE 149 00:05:42,611 --> 00:05:45,014 DON'T HAVE TO TRAVEL ACROSS THE 150 00:05:45,014 --> 00:05:47,316 COUNTRY AND IT'S A COST-SAVING 151 00:05:47,316 --> 00:05:48,884 MEASURE TO HAVE VIRTUAL MEETING 152 00:05:48,884 --> 00:05:50,419 BUT THERE'S SOMETHING SPECIAL 153 00:05:50,419 --> 00:05:51,687 ABOUT ENGAGING IN COUNCIL. 154 00:05:51,687 --> 00:05:57,726 SO I WANT THAT TO BE KIND OF A 155 00:05:57,726 --> 00:05:59,695 CULTURAL NORM FROM NOW ON. 156 00:05:59,695 --> 00:06:03,299 A GOOD QUESTION MARK IN MY 157 00:06:03,299 --> 00:06:04,500 PRESENTATION TO INDICATE TIMES 158 00:06:04,500 --> 00:06:06,869 FOR Q&A, SO PLEASE FEEL FREE, WE 159 00:06:06,869 --> 00:06:10,205 HAVE THE TIME TO DO THAT. 160 00:06:10,205 --> 00:06:12,608 IT IS A SPECIAL REPORT. 161 00:06:12,608 --> 00:06:14,677 I HAVE FROM THE BEGINNING FELT 162 00:06:14,677 --> 00:06:17,646 VERY COMPELLED TO MAKE SURE THAT 163 00:06:17,646 --> 00:06:19,381 I DISSEMINATE INFORMATION THAT 164 00:06:19,381 --> 00:06:22,084 IS CRITICAL TO OUR RESEARCH 165 00:06:22,084 --> 00:06:24,219 MISSION, INTRAMURALLY AND 166 00:06:24,219 --> 00:06:24,553 EXTRAMURALLY. 167 00:06:24,553 --> 00:06:25,955 AND BECAUSE OF SO MUCH GOING ON 168 00:06:25,955 --> 00:06:29,725 IT'S HARD TO KEEP A POWERPOINT 169 00:06:29,725 --> 00:06:31,360 STREAMLINED AND FOCUSED, RIGHT? 170 00:06:31,360 --> 00:06:33,862 IT IS FOCUSED AND WILL BE 171 00:06:33,862 --> 00:06:39,168 AVAILABLE TO YOU AFTER COUNCIL 172 00:06:39,168 --> 00:06:40,002 THROUGH THE RECORDING. 173 00:06:40,002 --> 00:06:43,939 WE HAVE A GUEST SPEAKER, RICK 174 00:06:43,939 --> 00:06:46,675 WOYCHIK, A FELLOW COLLEAGUE AND 175 00:06:46,675 --> 00:06:48,811 GREAT FRIEND WHO DIRECTS THE 176 00:06:48,811 --> 00:06:50,279 INSTITUTE OF ENVIRONMENTAL 177 00:06:50,279 --> 00:06:50,646 HEALTH SCIENCES. 178 00:06:50,646 --> 00:06:52,348 THERE'S A LOT HAPPENING IN THAT 179 00:06:52,348 --> 00:06:53,349 FIELD TODAY. 180 00:06:53,349 --> 00:06:55,751 I'M THRILLED TO SHARE THIS 181 00:06:55,751 --> 00:06:58,587 PLATFORM WITH MY DEPUTY 182 00:06:58,587 --> 00:07:01,123 DIRECTOR, MY PARTNER, NOT IN 183 00:07:01,123 --> 00:07:07,563 CRIME, GOOD TROUBLE, JENNIFER 184 00:07:07,563 --> 00:07:10,065 WEBSTER CYRIAQUE, WE'LL HAVE HER 185 00:07:10,065 --> 00:07:14,470 DESCRIBE PROGRESS MADE IN 186 00:07:14,470 --> 00:07:21,810 DISPARITIES, ENDEAVORS, WORK ON 187 00:07:21,810 --> 00:07:23,112 HEALTH DISPARITIES. 188 00:07:23,112 --> 00:07:29,685 BEFORE WE START IT'S FITTING TO 189 00:07:29,685 --> 00:07:30,986 ACKNOWLEDGE LEADERSHIP AND 190 00:07:30,986 --> 00:07:39,294 LEGACY LEFT BEHIND BY ALREADY 191 00:07:39,294 --> 00:07:42,131 HAROLD SLAT SLAVKIN. 192 00:07:42,131 --> 00:07:49,271 WE BENEFITED AND REMEMBER HIM 193 00:07:49,271 --> 00:07:50,239 FONDLY. 194 00:07:50,239 --> 00:07:55,177 HAL WAS SIXTH DIRECTOR, AN 195 00:07:55,177 --> 00:07:56,712 ICONOCLASTIC LEADER WHO 196 00:07:56,712 --> 00:07:58,914 BROADENED THE PORTFOLIO BY 197 00:07:58,914 --> 00:08:00,749 CHANGING THE NAME TO INCLUDE 198 00:08:00,749 --> 00:08:02,718 CRANIOFACIAL AND ALL THAT WE DO. 199 00:08:02,718 --> 00:08:07,222 THAT WAS A VERY STRATEGIC MOVE 200 00:08:07,222 --> 00:08:08,557 FOR US, CONGRESS APPROVAL WAS 201 00:08:08,557 --> 00:08:12,594 NOT EASY BUT HE PERSISTED AND 202 00:08:12,594 --> 00:08:15,764 WAS SUCCESSFUL. 203 00:08:15,764 --> 00:08:17,199 HAL PIONEERED, ON CAMPUS THE 204 00:08:17,199 --> 00:08:21,003 FIRST TO CHAIR A CAMPUS-WIDE 205 00:08:21,003 --> 00:08:25,274 GROUP TO FOCUS ON HEALTH 206 00:08:25,274 --> 00:08:26,575 DISPARITIES, A FIERCE ADVOCATE 207 00:08:26,575 --> 00:08:28,343 OF EQUAL OPPORTUNITY, SOCIAL 208 00:08:28,343 --> 00:08:33,816 JUSTICE, HEALTH FOR ALL. 209 00:08:33,816 --> 00:08:36,785 THE REST OF MY PRESENTATION HAL 210 00:08:36,785 --> 00:08:38,721 WOULD HAVE EMBRACED, HE 211 00:08:38,721 --> 00:08:40,389 SPEARHEADED FIRST SURGEON 212 00:08:40,389 --> 00:08:45,728 GENERAL'S REPORT, THAT WAS 213 00:08:45,728 --> 00:08:47,930 COMMISSIONED BY DAVID SATCHER, 214 00:08:47,930 --> 00:08:50,566 CHAMPIONED EFFORTS FOR PATIENT 215 00:08:50,566 --> 00:08:55,904 ADVOCATES, RETURNED TO USC WITH 216 00:08:55,904 --> 00:08:58,207 THE FIRST CENTER IN CRANIOFACIAL 217 00:08:58,207 --> 00:09:00,409 BIOLOGY AND GENETICS AND CREATED 218 00:09:00,409 --> 00:09:04,446 THE FIRST GRADUATE PROGRAM, 219 00:09:04,446 --> 00:09:07,416 HUGELY INNOVATIVE AND 220 00:09:07,416 --> 00:09:08,817 TRANSFORMATIVE INITIATIVES. 221 00:09:08,817 --> 00:09:11,553 WE SHARED CLOSE INTERESTS, I 222 00:09:11,553 --> 00:09:12,755 WASN'T HIS COLLABORATOR FORMALLY 223 00:09:12,755 --> 00:09:18,460 BUT I DID LOOK UP TO HIM AND 224 00:09:18,460 --> 00:09:20,562 SHARED MY DATA. 225 00:09:20,562 --> 00:09:22,297 PASSIONATE ABOUT CRANIOFACIAL 226 00:09:22,297 --> 00:09:22,698 BIOLOGY TOGETHER. 227 00:09:22,698 --> 00:09:30,939 I VIEWED HIM AS A BRILLIANT 228 00:09:30,939 --> 00:09:34,777 ORATOR WITH INTERPERSONAL 229 00:09:34,777 --> 00:09:36,845 SKILLS, A SPOKESPERSON. 230 00:09:36,845 --> 00:09:39,381 YOU CAN SEE HIM HERE WITH JACK 231 00:09:39,381 --> 00:09:46,688 AND A GROUP OF PAST PRESIDENTS. 232 00:09:46,688 --> 00:09:50,225 I WAS FORTUNATE TO VISIT HAL A 233 00:09:50,225 --> 00:09:52,494 FEW MONTHS AGO. 234 00:09:52,494 --> 00:09:53,629 MEMORIES ON THE BOTTOM RIGHT 235 00:09:53,629 --> 00:09:54,163 PERSIST. 236 00:09:54,163 --> 00:09:57,766 WE HAD A LOVELY VISIT. 237 00:09:57,766 --> 00:09:59,401 HE WAS IN GOOD SPIRITS AND WOULD 238 00:09:59,401 --> 00:10:01,036 LIKE TO BE REMEMBERED THAT WAY. 239 00:10:01,036 --> 00:10:02,304 THANK YOU, HAL, FOR ALL THAT 240 00:10:02,304 --> 00:10:04,339 YOU'VE DONE FOR US. 241 00:10:04,339 --> 00:10:06,642 I WANT TO SPEND A MINUTE IN 242 00:10:06,642 --> 00:10:07,509 SILENCE REMEMBERING HIS MEMORY 243 00:10:07,509 --> 00:10:10,312 WHICH WILL BE A BLESSING FOR US 244 00:10:10,312 --> 00:10:20,422 ALL. 245 00:10:31,834 --> 00:10:33,035 THANK YOU VERY MUCH. 246 00:10:33,035 --> 00:10:35,904 JUST SO YOU KNOW, THERE WILL BE 247 00:10:35,904 --> 00:10:37,639 A SYMPOSIUM HONORING HAL LIKELY 248 00:10:37,639 --> 00:10:44,079 NEXT YEAR IN NEW YORK WHERE ADCR 249 00:10:44,079 --> 00:10:49,451 MEETS AND A TRIBUTE IN A JDR 250 00:10:49,451 --> 00:10:50,452 ARTICLE, THERE ARE THINGS 251 00:10:50,452 --> 00:10:57,726 HAPPENING AROUND THE COUNTRY TO 252 00:10:57,726 --> 00:10:58,393 RECOGNIZE HAL'S CONTRIBUTIONS. 253 00:10:58,393 --> 00:11:00,629 I WANT TO GIVE YOU A BROAD SWEEP 254 00:11:00,629 --> 00:11:01,797 OF LANDSCAPE, NEW LEADERSHIP IN 255 00:11:01,797 --> 00:11:02,898 PLACE AT NIH. 256 00:11:02,898 --> 00:11:08,403 WE'RE IN WHAT WE CALL THE SILLY 257 00:11:08,403 --> 00:11:09,504 YEAR WITH ELECTIONS FORTHCOMING 258 00:11:09,504 --> 00:11:11,473 IN NOVEMBER, THE FUTURE REMAINS 259 00:11:11,473 --> 00:11:12,241 UNCERTAIN. 260 00:11:12,241 --> 00:11:14,543 THERE ARE THINGS THAT WE PAY 261 00:11:14,543 --> 00:11:15,644 ATTENTION TO, JUST BECAUSE THE 262 00:11:15,644 --> 00:11:18,146 WORLD AROUND US IS CHANGING. 263 00:11:18,146 --> 00:11:20,582 I'LL TALK ABOUT NEW INITIATIVES, 264 00:11:20,582 --> 00:11:21,884 GIVE AN UPDATE ON "ALL OF US," 265 00:11:21,884 --> 00:11:24,086 AND FOCUS MORE ON THE BUDGET AND 266 00:11:24,086 --> 00:11:30,092 WHAT IT IMPLIES FOR US FROM NOW 267 00:11:30,092 --> 00:11:30,859 ON. 268 00:11:30,859 --> 00:11:34,930 I'LL SHIFT FOCUS TO NIDCR, NEW 269 00:11:34,930 --> 00:11:38,100 HIRES, STAFFERS, TALKING ABOUT 270 00:11:38,100 --> 00:11:40,369 HOW THE 75th SIGNATURE 271 00:11:40,369 --> 00:11:42,371 INITIATIVE DRAW ON OVERALL 272 00:11:42,371 --> 00:11:44,339 CAMPUS-WIDE PLAN, AND HOW THIS 273 00:11:44,339 --> 00:11:47,843 IN THE END FUNDING DECISIONS, 274 00:11:47,843 --> 00:11:48,377 CONCEPT CLEARANCES, NEW 275 00:11:48,377 --> 00:11:50,679 INITIATIVES ARE SHAPED FOR THE 276 00:11:50,679 --> 00:11:50,913 FUTURE. 277 00:11:50,913 --> 00:11:52,014 SO HERE WAS MONICA BERTAGNOLLI 278 00:11:52,014 --> 00:11:56,685 WHO I INTRODUCED TO YOU LAST 279 00:11:56,685 --> 00:12:00,722 COUNCIL ROUND, DR. BERTAGNOLLI 280 00:12:00,722 --> 00:12:02,824 HAS EXPRESSED AN INTEREST IN 281 00:12:02,824 --> 00:12:03,959 TALKING TO COUNCIL IN MAY WHEN 282 00:12:03,959 --> 00:12:05,427 WE MEET IN PERSON. 283 00:12:05,427 --> 00:12:09,731 SHE COMES WITH EXPERTISE AS 284 00:12:09,731 --> 00:12:10,933 CLINICIAN SCIENTIST, HANDS-ON 285 00:12:10,933 --> 00:12:13,001 SURGEON CONDUCTING A VERY LARGE 286 00:12:13,001 --> 00:12:19,007 CLINICAL TRIAL WHEN SHE WAS AN 287 00:12:19,007 --> 00:12:20,108 MGH, CONDOMINIUM HER WITH HER 288 00:12:20,108 --> 00:12:25,914 BACKGROUND OF GROWING UP IN 289 00:12:25,914 --> 00:12:26,715 WYOMING, GROWING UP WITNESSING 290 00:12:26,715 --> 00:12:28,216 HOW DIFFICULT IT WAS TO ACCESS 291 00:12:28,216 --> 00:12:29,084 HEALTH CARE. 292 00:12:29,084 --> 00:12:31,820 SHE TALKS ABOUT HAVING TO TRAVEL 293 00:12:31,820 --> 00:12:36,858 100 MILES TO GET TO SCHOOL, SHE 294 00:12:36,858 --> 00:12:40,896 BRINGS THAT PERSPECTIVE OF 295 00:12:40,896 --> 00:12:41,797 ACCESS TO CARE, UNDERRESOURCED 296 00:12:41,797 --> 00:12:43,098 TO COMMUNITIES TO HEART IN HER 297 00:12:43,098 --> 00:12:45,367 MISSION AND HAS HIT THE GROUND 298 00:12:45,367 --> 00:12:45,767 RUNNING. 299 00:12:45,767 --> 00:12:48,136 WE HAVE OUR DEAR LARRY TABAK, 300 00:12:48,136 --> 00:12:51,840 WHO ASSISTS HER NOW IN KEEPING 301 00:12:51,840 --> 00:12:55,010 THE INSTITUTE, NAVIGATING THE 302 00:12:55,010 --> 00:12:56,778 FEDERAL LIFE, SO LARRY SERVED AS 303 00:12:56,778 --> 00:12:59,948 ACTING DIRECTOR BUT NOW IS BACK 304 00:12:59,948 --> 00:13:01,083 AS PRINCIPAL DEPUTY. 305 00:13:01,083 --> 00:13:02,384 THANK YOU, LARRY, FOR ALL THAT 306 00:13:02,384 --> 00:13:07,990 YOU'VE DONE FOR NIH AND NIDCR. 307 00:13:07,990 --> 00:13:18,533 YOU HEARD ABOUT ME JEAN MARRAZZO 308 00:13:21,069 --> 00:13:24,272 LAST TIME, ENGAGING INDIVIDUAL. 309 00:13:24,272 --> 00:13:26,608 WE HOPE FOR MORE COLLABORATIONS 310 00:13:26,608 --> 00:13:33,915 WITH NIAID IN THESE YEARS TO 311 00:13:33,915 --> 00:13:37,119 COME, WE'RE THRILLED TO WELCOME 312 00:13:37,119 --> 00:13:38,854 KYMRYN RATHMELL DIRECTOR OF NCI 313 00:13:38,854 --> 00:13:43,792 BRINGING EXPERTISE IN THE AREA 314 00:13:43,792 --> 00:13:45,027 OF RENAL CARCINOMAS, WIDELY 315 00:13:45,027 --> 00:13:47,829 RESPECTED FOR HER WORK. 316 00:13:47,829 --> 00:13:55,504 TO ADD TO THIS CADRE OF WOMEN 317 00:13:55,504 --> 00:13:58,440 LEADERS IS A GREAT PERSON TO 318 00:13:58,440 --> 00:14:01,610 COLLABORATE FOR CONTACTS WITH 319 00:14:01,610 --> 00:14:08,650 LEGISLATORS, OUR CONGRESSIONAL 320 00:14:08,650 --> 00:14:10,619 LIAISON KATE KLIMCZAK, WHO HAS 321 00:14:10,619 --> 00:14:12,587 CREATED A NOVEL INTERACTION, 322 00:14:12,587 --> 00:14:18,693 LUNCH AND LEARN SERIES WITH 323 00:14:18,693 --> 00:14:19,428 CONGRESSIONAL STAFFERS. 324 00:14:19,428 --> 00:14:22,431 THAT WILL ALLOW US TO TALK ABOUT 325 00:14:22,431 --> 00:14:26,368 ORAL HEALTH INITIATIVES THAT 326 00:14:26,368 --> 00:14:27,369 NEED SUPPORT. 327 00:14:27,369 --> 00:14:28,336 WHAT IS HAPPENING NIH-WIDE AND 328 00:14:28,336 --> 00:14:32,174 HOW IS IT INFLUENCED BY THE 329 00:14:32,174 --> 00:14:33,241 PRESIDENT'S IMPERATIVES? 330 00:14:33,241 --> 00:14:34,676 I WAS THRILLED TO SEE THIS 331 00:14:34,676 --> 00:14:38,313 INITIATIVE KICK OFF IN NOVEMBER. 332 00:14:38,313 --> 00:14:39,948 LONG OVERDUE, THE FOCUS ON 333 00:14:39,948 --> 00:14:41,483 WOMEN'S HEALTH RESEARCH. 334 00:14:41,483 --> 00:14:45,754 YOU CAN SEE HERE ON THE RIGHT 335 00:14:45,754 --> 00:14:49,357 NEW POLICY, REALLY KIND OF 336 00:14:49,357 --> 00:14:50,559 SPEARHEADED BY JILL BIDEN, DR. 337 00:14:50,559 --> 00:14:50,792 BIDEN. 338 00:14:50,792 --> 00:14:52,894 IT TALKS ABOUT THE NEED FOR US 339 00:14:52,894 --> 00:14:55,397 TO MAKE UP FOR THAT TIME AND 340 00:14:55,397 --> 00:14:58,900 RESOURCES AND REALLY LOOKING AT 341 00:14:58,900 --> 00:15:03,271 ALL, AS SHE SAID, AFFECTING 342 00:15:03,271 --> 00:15:04,372 WOMEN'S HEALTH. 343 00:15:04,372 --> 00:15:06,241 AND KAREN FROM YALE WILL PUT 344 00:15:06,241 --> 00:15:08,310 THESE THOUGHTS INTO ACTION, YOU 345 00:15:08,310 --> 00:15:10,745 CAN SEE FROM THE DRIVE THE 346 00:15:10,745 --> 00:15:12,147 MISSION IS REALLY ADVANCING 347 00:15:12,147 --> 00:15:17,085 WOMEN'S HEALTH RESEARCH IN THE 348 00:15:17,085 --> 00:15:17,953 U.S. 349 00:15:17,953 --> 00:15:24,192 THE SPECIFIC DIRECTORS ARE 350 00:15:24,192 --> 00:15:27,796 CLEAR, TO SET PRIORITIES, USE 351 00:15:27,796 --> 00:15:28,897 DATA SCIENCE, FOCUS ON 352 00:15:28,897 --> 00:15:33,935 DISPARITIES, UNDERSTAND THAT THE 353 00:15:33,935 --> 00:15:35,036 INTERSECTION OF WOMEN MINORITIES 354 00:15:35,036 --> 00:15:39,941 LGBTQ HAVE BEEN LARGELY IGNORED 355 00:15:39,941 --> 00:15:42,144 AND UNDERSERVED, SO ALL OF THESE 356 00:15:42,144 --> 00:15:43,678 TEN WILL TRANSLATE INTO GRANT 357 00:15:43,678 --> 00:15:45,080 OPPORTUNITIES, WE HOPE, EVEN IN 358 00:15:45,080 --> 00:15:47,582 TOUGH TIMES, THAT WILL DRIVE 359 00:15:47,582 --> 00:15:48,250 THIS INITIATIVE FORWARD. 360 00:15:48,250 --> 00:15:50,652 WE ARE FORTUNATE TO HAVE AN 361 00:15:50,652 --> 00:15:52,654 OFFICE OF RESEARCH ON WOMEN'S 362 00:15:52,654 --> 00:15:56,925 HEALTH CREATED WHEN VIVIAN PINN 363 00:15:56,925 --> 00:16:02,164 WAS HERE AT NIH, MOST OF THIS 364 00:16:02,164 --> 00:16:03,798 WORK THAT'S WIDE FEDERAL -- 365 00:16:03,798 --> 00:16:04,900 TRANSFEDERAL AGENCY INITIATIVE 366 00:16:04,900 --> 00:16:06,868 WILL BE COORDINATED THROUGH THIS 367 00:16:06,868 --> 00:16:09,938 OFFICE. 368 00:16:09,938 --> 00:16:14,743 WE HAVE STRONG COLLABORATIONS, 369 00:16:14,743 --> 00:16:17,179 CO-FUNDS SEVERAL PROJECTS 370 00:16:17,179 --> 00:16:22,083 ESPECIALLY IN SHÖGREN'S, 371 00:16:22,083 --> 00:16:23,618 TEMPOROMANDIBULAR, DENTAL AND 372 00:16:23,618 --> 00:16:26,021 ORAL FACIAL PAIN THAT AFFECT 373 00:16:26,021 --> 00:16:27,923 WOMEN DISPARATELY, THIS IN PLACE 374 00:16:27,923 --> 00:16:29,658 AND WE'LL BE ENGAGING IN THE 375 00:16:29,658 --> 00:16:30,992 BEST WAY POSSIBLE. 376 00:16:30,992 --> 00:16:33,728 NOW, YOU'VE ALL HEARD ABOUT "ALL 377 00:16:33,728 --> 00:16:35,997 OF US" GROWING BY LEAPS AND 378 00:16:35,997 --> 00:16:36,231 BOUNDS. 379 00:16:36,231 --> 00:16:37,098 PROGRESS ACTUALLY MADE OVER THE 380 00:16:37,098 --> 00:16:40,502 LAST YEAR HAS BEEN IMPRESSIVE. 381 00:16:40,502 --> 00:16:46,308 YOU CAN SEE HERE THAT WE'RE 382 00:16:46,308 --> 00:16:47,475 LOOKING FROM NOT JUST HOW MANY 383 00:16:47,475 --> 00:16:49,911 INDIVIDUALS WE ENROLL BUT HOW DO 384 00:16:49,911 --> 00:16:53,982 WE ENGAGE RESEARCHERS IN 385 00:16:53,982 --> 00:16:55,350 DIFFERENT PARTS OF THE WORLD AND 386 00:16:55,350 --> 00:16:57,452 CLEARLY THE U.S., EXPANDING DATA 387 00:16:57,452 --> 00:17:00,422 FOR THESE -- WHAT WILL BE A 388 00:17:00,422 --> 00:17:02,357 MILLION PARTICIPANTS WILL BE A 389 00:17:02,357 --> 00:17:04,893 HOLISTIC SELECTION, ONE OF A 390 00:17:04,893 --> 00:17:08,630 KIND ACTUALLY, THAT INVOLVES 391 00:17:08,630 --> 00:17:09,698 BIOSAMPLING, GENOME SEQUENCES, 392 00:17:09,698 --> 00:17:10,498 ENVIRONMENTAL DATA, PRINCIPAL 393 00:17:10,498 --> 00:17:10,899 MEASURES. 394 00:17:10,899 --> 00:17:12,367 I BRING THIS UP BECAUSE THERE 395 00:17:12,367 --> 00:17:16,304 ARE OPPORTUNITIES FOR MANY OF 396 00:17:16,304 --> 00:17:18,506 YOU TO PARTICIPATE IN THIS -- 397 00:17:18,506 --> 00:17:19,808 MINING THIS DATABASE, TAKING 398 00:17:19,808 --> 00:17:21,576 ADVANTAGE OF WHAT EXISTS THERE 399 00:17:21,576 --> 00:17:23,211 TO REALLY MAKE THE CONNECTION 400 00:17:23,211 --> 00:17:27,249 BETWEEN ORAL HEALTH AND SYSTEMIC 401 00:17:27,249 --> 00:17:27,649 HEALTH. 402 00:17:27,649 --> 00:17:31,953 SUCCESSFUL IN COLLECTING BLOOD 403 00:17:31,953 --> 00:17:33,288 AND URINE SAMPLES BUT NOT QUITE 404 00:17:33,288 --> 00:17:38,627 UP TO THE MARK FOR SALIVA 405 00:17:38,627 --> 00:17:38,860 SAMPLES. 406 00:17:38,860 --> 00:17:42,163 YOU CAN SEE THERE ARE 407 00:17:42,163 --> 00:17:43,898 APPROXIMATELY 8500 RESEARCHERS 408 00:17:43,898 --> 00:17:45,634 NOW INVOLVED IN STUDIES FROM 409 00:17:45,634 --> 00:17:46,935 "ALL OF US." 410 00:17:46,935 --> 00:17:50,238 I WANT YOU TO RESEARCH THAT, 411 00:17:50,238 --> 00:17:51,239 TALK TO PROGRAM STAFF, AND WE 412 00:17:51,239 --> 00:17:55,176 WILL DO ALL WE CAN TO SUPPORT 413 00:17:55,176 --> 00:17:59,948 YOUR INVOLVEMENT IN THIS VERY 414 00:17:59,948 --> 00:18:00,448 SIGNIFICANT INITIATIVE. 415 00:18:00,448 --> 00:18:04,019 ALERT YOU TO A NEW ARTICLE WE 416 00:18:04,019 --> 00:18:10,058 PUT TOGETHER IN CASTING FORTH 417 00:18:10,058 --> 00:18:13,328 OUR VISION FOR THE YEAR FROM 27 418 00:18:13,328 --> 00:18:16,298 DIRECTORS OF INSTITUTES, I 419 00:18:16,298 --> 00:18:18,266 BELIEVE NOW RELEASED IN "NATURE 420 00:18:18,266 --> 00:18:20,769 MEDICINE," REFER TO THAT FOR 421 00:18:20,769 --> 00:18:22,637 BROADER OVERVIEW OF THE PROGRAM. 422 00:18:22,637 --> 00:18:24,039 THRILLED TO WELCOME TWO 423 00:18:24,039 --> 00:18:28,109 EXECUTIVE LEADERS TO OUR STAFF, 424 00:18:28,109 --> 00:18:32,047 A WEALTH OF EXPERIENCE FROM 425 00:18:32,047 --> 00:18:33,448 NICHD RUNNING THE OFFICE OF 426 00:18:33,448 --> 00:18:38,153 I.T., BRINGS SUCH A POSITIVE 427 00:18:38,153 --> 00:18:39,688 ATTITUDE, AUBREY CALLWOOD, A 428 00:18:39,688 --> 00:18:41,022 CLIENT-ORIENTED WAY TO LOOK AT 429 00:18:41,022 --> 00:18:42,023 HIS JOB. 430 00:18:42,023 --> 00:18:43,958 SO IMPRESSED WITH HIM. 431 00:18:43,958 --> 00:18:52,200 THRILLED TO HAVE RACHEL 432 00:18:52,200 --> 00:18:53,201 SCEINERT, RESHAPING THE KEY 433 00:18:53,201 --> 00:18:56,237 OFFICE WHERE WE HOPE THE GAP 434 00:18:56,237 --> 00:18:59,207 BETWEEN EVIDENCE AND POLICY 435 00:18:59,207 --> 00:19:00,842 REFORM CAN GET NARROWER THROUGH 436 00:19:00,842 --> 00:19:02,811 THE WORK OF THIS PARTICULAR 437 00:19:02,811 --> 00:19:03,678 OFFICE, RACHEL, WELCOME. 438 00:19:03,678 --> 00:19:11,019 WE LOOK FORWARD TO YOUR 439 00:19:11,019 --> 00:19:12,187 LEADERSHIP. 440 00:19:12,187 --> 00:19:16,691 PROGRAM STAFF, SCOTT FROM 441 00:19:16,691 --> 00:19:18,259 ACADEMIA, DIRECTING TISSUE 442 00:19:18,259 --> 00:19:23,498 ENGINEERING AND THIS 443 00:19:23,498 --> 00:19:26,267 REGENERATIVE MEDICINE PROGRAM 444 00:19:26,267 --> 00:19:30,205 WITH BILL ELWOOD, DISEASES ARE 445 00:19:30,205 --> 00:19:33,341 PREVENTIBLE AND CONDITIONING 446 00:19:33,341 --> 00:19:34,576 BEHAVIOR AND ATTITUDES, UPSTREAM 447 00:19:34,576 --> 00:19:35,810 HEALTH IS A VERY IMPORTANT 448 00:19:35,810 --> 00:19:38,179 ASPECT OF WHAT WE DO. 449 00:19:38,179 --> 00:19:39,381 BILL, WELCOME. 450 00:19:39,381 --> 00:19:41,649 WE LOOK FORWARD TO YOUR 451 00:19:41,649 --> 00:19:41,950 LEADERSHIP. 452 00:19:41,950 --> 00:19:42,984 A MOMENT TO SHARE WITH YOU WHAT 453 00:19:42,984 --> 00:19:47,155 I SHARED WITH MY FELLOW 454 00:19:47,155 --> 00:19:47,455 COLLEAGUES. 455 00:19:47,455 --> 00:19:49,424 THERE ARE DIFFERENT WAYS ONE CAN 456 00:19:49,424 --> 00:19:51,960 TALK ABOUT ORAL HEALTH WHEN 457 00:19:51,960 --> 00:19:55,029 YOU'RE AT THE TABLE. 458 00:19:55,029 --> 00:20:00,335 YOU ACTUALLY TALK AND I'VE DONE 459 00:20:00,335 --> 00:20:03,037 THAT TO THE BEST OF MY ABILITY. 460 00:20:03,037 --> 00:20:04,873 OTHER WAYS TO ENGAGE INSTITUTES, 461 00:20:04,873 --> 00:20:08,743 SINCE WE HAD TAKEN THIS BRAVE 462 00:20:08,743 --> 00:20:10,145 COURAGEOUS MOVE TO REINSTATE 463 00:20:10,145 --> 00:20:13,014 DENTAL PUBLIC HEALTH TRAINING IN 464 00:20:13,014 --> 00:20:14,649 THIS MANNER, TO OFFER ADDITIONAL 465 00:20:14,649 --> 00:20:18,353 TWO YEARS TO OUR TRAINEES 466 00:20:18,353 --> 00:20:20,321 FOCUSED ON POSTDOCTORAL LEVEL 467 00:20:20,321 --> 00:20:22,190 INQUIRY, AND WE THOUGHT, YOU 468 00:20:22,190 --> 00:20:24,692 KNOW, WE CAN STAY WITHIN OUR 469 00:20:24,692 --> 00:20:28,797 COMFORT ZONE AND FOCUS ON A 470 00:20:28,797 --> 00:20:30,064 SECONDARY ANALYSIS AND, YOU 471 00:20:30,064 --> 00:20:32,033 KNOW, WE CAN DO THAT EASILY. 472 00:20:32,033 --> 00:20:34,569 BUT CAME THE OPPORTUNITY FOR US 473 00:20:34,569 --> 00:20:36,871 TO ACTUAL MODEL A PROGRAM THAT I 474 00:20:36,871 --> 00:20:38,506 HOPE OTHER PROGRAMS IN THIS 475 00:20:38,506 --> 00:20:40,809 COUNTRY WILL TAKE NOTE OF. 476 00:20:40,809 --> 00:20:43,011 AND SO WHAT WE'RE DOING IS THIS 477 00:20:43,011 --> 00:20:45,079 OUTREACH, TO GET ALL THE 478 00:20:45,079 --> 00:20:46,281 INSTITUTES TO IDENTIFY PROJECTS 479 00:20:46,281 --> 00:20:48,516 THAT WOULD BENEFIT FROM THE 480 00:20:48,516 --> 00:20:49,884 INCLUSION OF ORAL HEALTH AND 481 00:20:49,884 --> 00:20:52,420 THIS IS POPULATION HEALTH 482 00:20:52,420 --> 00:20:53,721 SCIENCES FOCUSED. 483 00:20:53,721 --> 00:20:54,923 THERE'S LOTS OF SCIENCE GOING 484 00:20:54,923 --> 00:20:57,559 ON, WE WANTED TO BE COMMUNITY 485 00:20:57,559 --> 00:20:57,859 BASED. 486 00:20:57,859 --> 00:21:03,198 AND THE RESPONSE SO FAR HAS BEEN 487 00:21:03,198 --> 00:21:05,133 ABSOLUTELY ENCOURAGING, VERY 488 00:21:05,133 --> 00:21:06,768 POSITIVE. 489 00:21:06,768 --> 00:21:08,536 TRAINEES WILL HAVE A NICE 490 00:21:08,536 --> 00:21:10,505 PORTFOLIO OF PROJECTS TO CHOOSE 491 00:21:10,505 --> 00:21:14,676 FROM WHERE THEY WILL WORK IN 492 00:21:14,676 --> 00:21:15,343 ANOTHER INSTITUTE, NIDCR 493 00:21:15,343 --> 00:21:15,977 SUPPORTS THIS. 494 00:21:15,977 --> 00:21:18,513 WE'RE ONE OF THE ONLY TWO 495 00:21:18,513 --> 00:21:19,280 INSTITUTES IN THE COUNTRY, 496 00:21:19,280 --> 00:21:22,450 ENTITIES IN THE COUNTRY, THAT 497 00:21:22,450 --> 00:21:23,351 ACTUALLY OFFER STIPENDS FOR 498 00:21:23,351 --> 00:21:25,386 PUBLIC HEALTH RESEARCH TRAINING. 499 00:21:25,386 --> 00:21:26,387 I'M HOPING THERE'S ANYONE HERE 500 00:21:26,387 --> 00:21:28,590 THAT IS A PROGRAM DIRECTOR, 501 00:21:28,590 --> 00:21:30,124 PLEASE PASS THIS WORD AROUND, 502 00:21:30,124 --> 00:21:33,061 DEANS AS WELL. 503 00:21:33,061 --> 00:21:36,030 IT'S IMPORTANT THAT WE INTERACT. 504 00:21:36,030 --> 00:21:37,565 WE'RE HERE AT NIDCR TO WELCOME 505 00:21:37,565 --> 00:21:41,069 INDIVIDUALS WHO WANT TO ROTATE 506 00:21:41,069 --> 00:21:41,870 THROUGH RESIDENCY PROGRAM AND 507 00:21:41,870 --> 00:21:43,037 RESOURCES WE HAVE HERE. 508 00:21:43,037 --> 00:21:45,773 THESE ARE OUR FIVE TRAINEES, THE 509 00:21:45,773 --> 00:21:47,742 FIRST YEAR, NOW THE SECOND YEAR 510 00:21:47,742 --> 00:21:48,943 SENIOR TRAINEES, THREE IN YEAR 511 00:21:48,943 --> 00:21:52,447 ONE WHO ARE REALLY REMARKABLE 512 00:21:52,447 --> 00:21:54,282 INDIVIDUALS, VERY COMMITTED. 513 00:21:54,282 --> 00:21:58,152 VERY, VERY SPECIAL THANK YOU AND 514 00:21:58,152 --> 00:22:00,088 ACKNOWLEDGMENT TO DR. HOFFMAN. 515 00:22:00,088 --> 00:22:02,190 MATT HAS DECIDED TO ACTUALLY 516 00:22:02,190 --> 00:22:06,227 SPEND MORE TIME IN HIS NATIVE 517 00:22:06,227 --> 00:22:07,762 NEW ZEALAND WITH FAMILY AND HE 518 00:22:07,762 --> 00:22:11,266 RETURNS TO THE U.S. OFF AND ON. 519 00:22:11,266 --> 00:22:13,368 MATT HAS HAD A STEPDOWN FROM 520 00:22:13,368 --> 00:22:15,837 POSITION OF SCIENTIFIC DIRECTOR 521 00:22:15,837 --> 00:22:18,239 AND VERY RESPONSIBLY PHASING OUT 522 00:22:18,239 --> 00:22:20,975 HIS LAB TO BE ABLE TO -- TO MAKE 523 00:22:20,975 --> 00:22:21,910 THE RETIREMENT POSSIBLE. 524 00:22:21,910 --> 00:22:23,611 HE'S DONE ANYTIME A VERY, VERY 525 00:22:23,611 --> 00:22:25,713 ORGANIZED WAY SO THANK YOU, 526 00:22:25,713 --> 00:22:26,014 MATT. 527 00:22:26,014 --> 00:22:29,551 BUT MORE THAN ANYTHING ELSE, 528 00:22:29,551 --> 00:22:32,921 REALLY YOUR CONTRIBUTIONS TO 529 00:22:32,921 --> 00:22:37,525 NIDCR, ITS PROGRAMMING, 530 00:22:37,525 --> 00:22:38,426 INTRAMURAL RESEARCH, MENTORING 531 00:22:38,426 --> 00:22:41,596 TRAINING ALL NOW LEADERS IN THE 532 00:22:41,596 --> 00:22:43,231 FIELD, OF COURSE FOR 533 00:22:43,231 --> 00:22:44,866 RESTRUCTURAL THE INTRAMURAL 534 00:22:44,866 --> 00:22:46,534 PROGRAM AND ALLOWING FOR STAFF 535 00:22:46,534 --> 00:22:49,771 BE TO MAP, THE O.U., WE THANK 536 00:22:49,771 --> 00:22:53,875 YOU FOR THAT SERVICE. 537 00:22:53,875 --> 00:22:55,009 VERY GRATEFUL TO THOSE WHO 538 00:22:55,009 --> 00:22:59,147 STEPPED UP AS A TEAM, DEFINITELY 539 00:22:59,147 --> 00:23:03,184 A TEAM OF PARTNERS, TO KEEP ALL 540 00:23:03,184 --> 00:23:04,385 INTRAMURAL RESEARCH FUNCTIONS 541 00:23:04,385 --> 00:23:06,554 AND STRUCTURE MOVING FORWARD FOR 542 00:23:06,554 --> 00:23:08,323 THE FUTURE. 543 00:23:08,323 --> 00:23:09,624 WE'LL BE CONTEMPLATING THE 544 00:23:09,624 --> 00:23:11,426 SEARCH FOR THE NEW SCIENTIFIC 545 00:23:11,426 --> 00:23:15,430 DIRECTOR IN THE CONTEXT OF OUR 546 00:23:15,430 --> 00:23:16,064 BUDGETARY SITUATION. 547 00:23:16,064 --> 00:23:18,800 SO WE HAVE TO KIND OF ABLE TO 548 00:23:18,800 --> 00:23:20,802 BALANCE WHAT WE WANT TO DO WITH 549 00:23:20,802 --> 00:23:22,236 WHAT WE ACTUALLY HAVE IN TERMS 550 00:23:22,236 --> 00:23:24,739 OF RESOURCES TO DO. 551 00:23:24,739 --> 00:23:26,908 SO THANK YOU INDU AND JAY FOR 552 00:23:26,908 --> 00:23:35,917 ALL YOU DO ON A DAILY BASIS. 553 00:23:35,917 --> 00:23:37,685 JENNIFER, WE LOVE BEING OUT 554 00:23:37,685 --> 00:23:39,887 THERE, ENGAGING WITH YOU TO THE 555 00:23:39,887 --> 00:23:40,989 BEST OF OUR ABILITIES. 556 00:23:40,989 --> 00:23:42,924 IF YOU FEEL PRESENCE ON YOUR 557 00:23:42,924 --> 00:23:49,697 CAMPUS ESPECIALLY TALKING TO 558 00:23:49,697 --> 00:23:53,001 HIGHER LEVEL ADMINISTRATORS ARE 559 00:23:53,001 --> 00:23:53,868 HELPFUL, WE'RE WILLING, 560 00:23:53,868 --> 00:23:55,069 ESPECIALLY WITH STUDENTS AND 561 00:23:55,069 --> 00:23:55,870 EARLY CAREER INVESTIGATORS. 562 00:23:55,870 --> 00:24:00,208 THIS IS WHAT WE'VE DONE SINCE 563 00:24:00,208 --> 00:24:00,508 SEPTEMBER. 564 00:24:00,508 --> 00:24:01,743 LEADERSHIP ACTIVITIES ACROSS 565 00:24:01,743 --> 00:24:07,115 CAMPUS, TO MAKE SURE WE ARE WELL 566 00:24:07,115 --> 00:24:08,316 REPRESENTED, AND THIS IS 567 00:24:08,316 --> 00:24:09,951 JENNIFER, BUT OUR PROGRAM STAFF 568 00:24:09,951 --> 00:24:11,719 ARE HIGHLY ENTER AVE WITH PEERS 569 00:24:11,719 --> 00:24:13,888 AROUND CAMPUS, AND THAT YOU WILL 570 00:24:13,888 --> 00:24:15,523 APPRECIATE IS AN IMPORTANT 571 00:24:15,523 --> 00:24:18,593 STRATEGIC MOVE SO WE CAN GET A 572 00:24:18,593 --> 00:24:22,330 LOT MORE AWARENESS AND HENCE 573 00:24:22,330 --> 00:24:26,567 SUPPORT FOR OUR INITIATIVES. 574 00:24:26,567 --> 00:24:33,508 I DID MENTION DR. BERTAGNOLLI 575 00:24:33,508 --> 00:24:39,047 HIT THE GROUND RUNG. 576 00:24:39,047 --> 00:24:39,547 - RUNNING. 577 00:24:39,547 --> 00:24:41,482 SHE WILL NOT USE THE TERM BIG 578 00:24:41,482 --> 00:24:43,451 AND SMALL INSTITUTE ANYMORE 579 00:24:43,451 --> 00:24:44,419 BECAUSE THE BUDGET DOES NOT 580 00:24:44,419 --> 00:24:46,120 DRIVE THE VISION OF WHO WE ARE, 581 00:24:46,120 --> 00:24:48,189 THAT IS TRUE. 582 00:24:48,189 --> 00:24:49,057 THESE ARE GUIDING PRINCIPLES 583 00:24:49,057 --> 00:24:53,327 THAT CAME TO US FROM HER OFFICE, 584 00:24:53,327 --> 00:24:55,263 I HAVEN'T CHANGED ANYTHING, 585 00:24:55,263 --> 00:24:55,897 VERBATIM, JUST HIGHLIGHTED WHAT 586 00:24:55,897 --> 00:24:57,298 I THINK ARE IMPORTANT. 587 00:24:57,298 --> 00:24:59,400 SHE SAYS OUR WORK HERE WILL NOT 588 00:24:59,400 --> 00:25:02,136 BE FINISHED WHEN WE JUST DELIVER 589 00:25:02,136 --> 00:25:04,105 AND BRAG OR ENGAGE IN SCIENTIFIC 590 00:25:04,105 --> 00:25:04,572 DISCOVERY. 591 00:25:04,572 --> 00:25:06,307 OUR WORK IS FINISHED WHEN ALL 592 00:25:06,307 --> 00:25:11,045 PEOPLE LIVE LONG AND HEALTHY 593 00:25:11,045 --> 00:25:15,616 LIVES.. 594 00:25:15,616 --> 00:25:17,785 SHE CARES DEEPLY ABOUT PATIENTS 595 00:25:17,785 --> 00:25:19,020 AS PARTNERS, PARTNERS IN 596 00:25:19,020 --> 00:25:19,320 COMMUNITY. 597 00:25:19,320 --> 00:25:20,755 READ BETWEEN THE LINES TO KNOW 598 00:25:20,755 --> 00:25:23,691 WHAT THIS MEANS. 599 00:25:23,691 --> 00:25:25,793 TO TACKLE THE MOST COMPLEX 600 00:25:25,793 --> 00:25:26,060 PROBLEMS. 601 00:25:26,060 --> 00:25:28,196 I DON'T BELIEVE THIS IS DRIVEN 602 00:25:28,196 --> 00:25:31,032 BY CONGRESS. 603 00:25:31,032 --> 00:25:32,567 THIS IS COMING FROM DR. 604 00:25:32,567 --> 00:25:34,402 BERTAGNOLLI'S SOUL, AS I SEE IT. 605 00:25:34,402 --> 00:25:36,738 SHE CARES ABOUT NEW DATA 606 00:25:36,738 --> 00:25:38,806 ANALYTICS, AND HOW WE CAN USE 607 00:25:38,806 --> 00:25:41,309 A.I. AND MACHINE LEARNING TOOLS 608 00:25:41,309 --> 00:25:47,348 TO DIVERSIFY OUR FIELDS OF 609 00:25:47,348 --> 00:25:48,216 INTEREST OR DISEASES, CARE, 610 00:25:48,216 --> 00:25:49,016 SCIENTIFIC INTERESTS. 611 00:25:49,016 --> 00:25:50,184 IT'S AVAILABLE FOR YOU. 612 00:25:50,184 --> 00:25:53,154 THERE'S A LOT NOW AVAILABLE 613 00:25:53,154 --> 00:25:56,424 ONLINE OF HER WRITTEN AND VERBAL 614 00:25:56,424 --> 00:25:57,191 COMMUNICATIONS. 615 00:25:57,191 --> 00:26:00,394 SHE SPEAKS ABOUT THE BUDGET, WE 616 00:26:00,394 --> 00:26:02,463 SHOULD REMAIN HOPEFUL SO WE'RE 617 00:26:02,463 --> 00:26:05,199 SUBJECT TO DRASTIC CUTS BUT DO 618 00:26:05,199 --> 00:26:07,935 EXPECT A FLAT BUDGET FOR FISCAL 619 00:26:07,935 --> 00:26:10,138 YEAR 24. 620 00:26:10,138 --> 00:26:12,206 AND LIKELY A REDUCTION, MAYBE 621 00:26:12,206 --> 00:26:14,942 ANOTHER FLAT BUDGET, IN FISCAL 622 00:26:14,942 --> 00:26:15,710 YEAR 25. 623 00:26:15,710 --> 00:26:18,012 SO WHEN WE HAVE THAT, THE 624 00:26:18,012 --> 00:26:20,748 PARTNERSHIP WITH STAKEHOLDERS 625 00:26:20,748 --> 00:26:22,483 BECOMES EVEN MORE CRITICAL. 626 00:26:22,483 --> 00:26:26,120 AND OF COURSE OUR INTRAMURAL 627 00:26:26,120 --> 00:26:29,423 PROGRAM BECOMES SENSITIVE TO 628 00:26:29,423 --> 00:26:33,327 BUDGET CUTS AS SHE NOTED HERE. 629 00:26:33,327 --> 00:26:35,763 TAKE ALL THIS INTO STRIDE, WHAT 630 00:26:35,763 --> 00:26:37,698 DO WE DO FOR THE NEXT 25 YEARS 631 00:26:37,698 --> 00:26:41,435 WHEN WE HAVE THESE CHALLENGES 632 00:26:41,435 --> 00:26:44,272 AND UNSURPASSED OPPORTUNITIES TO 633 00:26:44,272 --> 00:26:46,474 ADVANCE OUR SCIENCE, IT TAKES 634 00:26:46,474 --> 00:26:46,808 SOME THINKING. 635 00:26:46,808 --> 00:26:50,178 I WANT TO ENGAGE COUNCIL IN THIS 636 00:26:50,178 --> 00:26:51,179 DELIBERATION, AS MY RIGHT HAND 637 00:26:51,179 --> 00:26:54,448 ADVISORY GROUP. 638 00:26:54,448 --> 00:26:57,852 THE ONLY ONE WE HAVE AT NIDCR. 639 00:26:57,852 --> 00:27:01,022 OUR BUDGET IS FLAT FOR NOW, 640 00:27:01,022 --> 00:27:02,223 CONTINUING RESOLUTION WILL COME 641 00:27:02,223 --> 00:27:03,758 FORTH HOPEFULLY LIFTED ON THE 642 00:27:03,758 --> 00:27:05,393 8th OF MARCH, WE'LL HAVE SOME 643 00:27:05,393 --> 00:27:09,897 IDEA AS TO HOW WE ARE SHAPED FOR 644 00:27:09,897 --> 00:27:12,200 FISCAL YEAR 24. 645 00:27:12,200 --> 00:27:13,267 WE REMAIN STRONGLY COMMITTED, 646 00:27:13,267 --> 00:27:15,670 80% OF OUR BUDGET IS FOCUSED ON 647 00:27:15,670 --> 00:27:16,904 EXTRAMURAL RESEARCH. 648 00:27:16,904 --> 00:27:18,973 AND THE INTRAMURAL RESEARCH 649 00:27:18,973 --> 00:27:20,741 PROGRAM IS SIMPLY THE FLAGSHIP, 650 00:27:20,741 --> 00:27:23,811 JEWEL IN THE CROWN FOR US ON 651 00:27:23,811 --> 00:27:26,113 CAMPUS AND WORLDWIDE. 652 00:27:26,113 --> 00:27:28,816 RESEARCHERS IN THE INTRAMURAL 653 00:27:28,816 --> 00:27:33,454 PROGRAM ARE SIMPLY CUTTING EDGE. 654 00:27:33,454 --> 00:27:35,289 STRINGENTLY REVIEW, PUBLISH IN 655 00:27:35,289 --> 00:27:36,424 HIGH QUALITY JOURNAL, MOVING 656 00:27:36,424 --> 00:27:38,826 FIELD OF FOUNDATIONAL AND 657 00:27:38,826 --> 00:27:39,427 TRANSLATIONAL SCIENCES REALLY 658 00:27:39,427 --> 00:27:39,894 WELL. 659 00:27:39,894 --> 00:27:42,630 OF COURSE WE HAVE RESEARCH 660 00:27:42,630 --> 00:27:42,930 MANAGEMENT. 661 00:27:42,930 --> 00:27:46,133 SO THIS IS FROM THE DIVISION OF 662 00:27:46,133 --> 00:27:48,903 EXTRAMURAL RESEARCH, AND ITS 663 00:27:48,903 --> 00:27:54,609 DIRECTOR ALREADY LILLIAN SHUM 664 00:27:54,609 --> 00:27:57,445 WHO ADVISEs ME WHAT WE NEED TO 665 00:27:57,445 --> 00:27:57,879 DO. 666 00:27:57,879 --> 00:27:59,747 WE'LL CONTINUE TO PROVIDE STABLE 667 00:27:59,747 --> 00:28:01,582 LEVELS OF SUPPORT FOR HIGH 668 00:28:01,582 --> 00:28:02,817 QUALITY RESEARCH AND TRAINING. 669 00:28:02,817 --> 00:28:06,320 WE'RE GOING TO MEASURE WHAT THAT 670 00:28:06,320 --> 00:28:10,358 MEANS MUCH MORE DISCRETELY. 671 00:28:10,358 --> 00:28:13,227 NON-COMPETING, WHICH IS FIVE, 672 00:28:13,227 --> 00:28:13,995 NON-COMPETING, ALREADY GOTTEN 673 00:28:13,995 --> 00:28:15,630 AWARD AND GOING FOR SECOND YEAR, 674 00:28:15,630 --> 00:28:18,466 THIRD YEAR, WILL BE AWARDED 90% 675 00:28:18,466 --> 00:28:22,069 DURING THE C.R. PERIOD. 676 00:28:22,069 --> 00:28:22,637 SUPPORT FOR EARLY-STAGE 677 00:28:22,637 --> 00:28:24,372 INVESTIGATORS REMAINS VERY 678 00:28:24,372 --> 00:28:24,839 STRONG. 679 00:28:24,839 --> 00:28:26,774 WE WILL NOT COMPROMISE ON THAT 680 00:28:26,774 --> 00:28:32,246 PATHWAY OR THAT PIPELINE THAT WE 681 00:28:32,246 --> 00:28:33,781 CONSIDER CRITICAL FOR THE 682 00:28:33,781 --> 00:28:36,517 FUTURE, NO REDUCTION TO R01 AND 683 00:28:36,517 --> 00:28:38,052 EQUIVALENTS BUT COMPETING 684 00:28:38,052 --> 00:28:40,154 NON-MODULAR WILL BE SUBJECT TO 685 00:28:40,154 --> 00:28:42,089 10%, A REASONABLE REDUCTION. 686 00:28:42,089 --> 00:28:46,160 AND OF COURSE NO REDUCTIONS TO 687 00:28:46,160 --> 00:28:48,229 RESEARCH AND CAREER DEVELOPMENT. 688 00:28:48,229 --> 00:28:50,398 THE FUNDING -- THERE ARE OTHER 689 00:28:50,398 --> 00:28:52,500 FUNDING DECISIONS THAT WE HAVE 690 00:28:52,500 --> 00:29:01,342 TO MAKE, WHICH IS COMPETING 691 00:29:01,342 --> 00:29:04,645 R01s AND EQUIVALENTS 9%, 692 00:29:04,645 --> 00:29:06,681 COMPETING NON-MODERATE 15%, 693 00:29:06,681 --> 00:29:07,548 ADDITIONAL REDUCTIONS ON A 694 00:29:07,548 --> 00:29:08,482 GRADED SCALE. 695 00:29:08,482 --> 00:29:10,217 THIS IS TO ALLOW US THE BUDGET 696 00:29:10,217 --> 00:29:13,287 AND ROOM TO BE FUNDING THOSE 697 00:29:13,287 --> 00:29:14,055 EARLY-STAGE INVESTIGATORS AT 698 00:29:14,055 --> 00:29:16,023 HIGHER LEVEL THAN WE ARE NOW. 699 00:29:16,023 --> 00:29:18,526 TYPE 2 APPLICATIONS ARE EXPECTED 700 00:29:18,526 --> 00:29:21,595 TO BE LIMITED TO NO MORE THAN 701 00:29:21,595 --> 00:29:23,331 20% BUDGET INCREASES OVER THE 702 00:29:23,331 --> 00:29:25,533 LAST AWARD PERIOD. 703 00:29:25,533 --> 00:29:26,934 THESE ARE CONSERVATIVE CUTS, AND 704 00:29:26,934 --> 00:29:28,669 I HOPE THAT YOU ALL UNDERSTAND 705 00:29:28,669 --> 00:29:30,771 THAT AND CAN WORK WITH YOUR 706 00:29:30,771 --> 00:29:33,307 PROGRAM STAFF IF YOU NEED 707 00:29:33,307 --> 00:29:33,541 DETAILS. 708 00:29:33,541 --> 00:29:36,243 AND AS YOU CAN SEE, ALL THE 709 00:29:36,243 --> 00:29:38,346 OTHER RELEVANT FACTORS WE WILL 710 00:29:38,346 --> 00:29:39,413 CONSIDER IN OUR FUNDING 711 00:29:39,413 --> 00:29:39,914 DECISIONS. 712 00:29:39,914 --> 00:29:44,952 IT WILL BE VERY HOLISTIC, VERY 713 00:29:44,952 --> 00:29:46,253 HUMANISTIC, AND VERY QUALITY 714 00:29:46,253 --> 00:29:47,154 SCIENCE DRIVEN. 715 00:29:47,154 --> 00:29:48,689 THAT'S HOW WE MAKE OUR DECISIONS 716 00:29:48,689 --> 00:29:49,657 ON FUNDING. 717 00:29:49,657 --> 00:29:53,060 ARE THERE ANY QUESTIONS FROM 718 00:29:53,060 --> 00:29:53,294 COUNCIL? 719 00:29:53,294 --> 00:29:55,596 I'M SURE THOSE ON THE WEBINAR 720 00:29:55,596 --> 00:29:57,331 CAN ENTER THOSE AND WE'LL ANSWER 721 00:29:57,331 --> 00:30:03,804 THEM AS SOON AS WE GET THEM. 722 00:30:03,804 --> 00:30:10,544 ANY QUESTIONS FROM YOU? 723 00:30:10,544 --> 00:30:11,812 SEVERAL HANDS RAISED. 724 00:30:11,812 --> 00:30:16,183 CAN YOU SPEAK UP BECAUSE I CAN'T 725 00:30:16,183 --> 00:30:21,188 SEE EVERYONE. 726 00:30:21,188 --> 00:30:21,589 PAUL? 727 00:30:21,589 --> 00:30:22,256 DR. KREBSBACH? 728 00:30:22,256 --> 00:30:26,427 >> PROPOSED CUTS YOU JUST 729 00:30:26,427 --> 00:30:28,396 SHOWED, THOSE ARE PROPOSED 730 00:30:28,396 --> 00:30:29,930 DURING THIS INTERIM -- DURING 731 00:30:29,930 --> 00:30:32,767 THE CONTINUING RESOLUTION OR ARE 732 00:30:32,767 --> 00:30:34,735 THOSE GOING TO BE PASSED FORWARD 733 00:30:34,735 --> 00:30:36,237 REGARDLESS OF WHAT -- 734 00:30:36,237 --> 00:30:37,204 >> GOOD QUESTION. 735 00:30:37,204 --> 00:30:39,173 DEFINITELY THROUGH THE C.R. 736 00:30:39,173 --> 00:30:42,643 I'LL LET DR. SHUM PITCH IN. 737 00:30:42,643 --> 00:30:45,813 I'M PREDICTING THIS IS FISCAL 738 00:30:45,813 --> 00:30:47,148 YEAR 24 ARRANGEMENT, FISCAL YEAR 739 00:30:47,148 --> 00:30:51,552 24, BECAUSE THAT BUDGET WILL BE 740 00:30:51,552 --> 00:30:52,219 ASSIGNED HOPEFULLY IN MARCH, 741 00:30:52,219 --> 00:30:54,622 EVEN IF WE CONTINUE THE C.R. WE 742 00:30:54,622 --> 00:30:56,057 NEED TO HAVE REDUCTIONS IN 743 00:30:56,057 --> 00:30:56,657 PLACE. 744 00:30:56,657 --> 00:30:58,793 MY GUESS IS FISCAL YEAR 24 AS WE 745 00:30:58,793 --> 00:31:00,861 AWAIT NEWS ON WHAT THE NEXT YEAR 746 00:31:00,861 --> 00:31:01,862 WOULD LOOK LIKE. 747 00:31:01,862 --> 00:31:10,871 LILLIAN, CAN YOU COMMENT PLEASE? 748 00:31:10,871 --> 00:31:13,908 >> SO, INTERIM POLICY IS 749 00:31:13,908 --> 00:31:15,876 OFFERING THE FRAMEWORK FOR THE 750 00:31:15,876 --> 00:31:17,511 FINAL POLICY, BUT I DO NOT 751 00:31:17,511 --> 00:31:19,814 EXPECT TO A FINAL POLICY TO HAVE 752 00:31:19,814 --> 00:31:22,783 MAJOR DEVIATIONS FROM WHAT WE 753 00:31:22,783 --> 00:31:25,953 ALREADY PUBLISHED. 754 00:31:25,953 --> 00:31:29,123 WE MIGHT TWEAK ON THE REDUCTIONS 755 00:31:29,123 --> 00:31:33,160 FOR ESI, FOR EXAMPLE, THAT'S 756 00:31:33,160 --> 00:31:35,229 DEFINITELY AN INSTITUTE PRIOR 757 00:31:35,229 --> 00:31:38,165 AND WE MIGHT TWEAK A LITTLE BIT 758 00:31:38,165 --> 00:31:45,906 ON NON-COMPETING. 759 00:31:45,906 --> 00:31:49,910 >> ANY OTHER QUESTIONS? 760 00:31:49,910 --> 00:31:52,513 NO ONE ELSE? 761 00:31:52,513 --> 00:31:52,947 THANKS. 762 00:31:52,947 --> 00:31:53,214 OKAY. 763 00:31:53,214 --> 00:31:54,915 WE CAN WRITE THEM IN THE CHAT 764 00:31:54,915 --> 00:32:05,259 AND GET BACK TO IT. 765 00:32:06,494 --> 00:32:08,095 NOW, WHEN WE EXPERIENCED THIS 766 00:32:08,095 --> 00:32:12,266 WAVE OF OPPORTUNITY AND CHANGE, 767 00:32:12,266 --> 00:32:13,267 SWEEPING NIH, IN WHATEVER SHAPE 768 00:32:13,267 --> 00:32:15,669 OR FORM IT MIGHT TAKE IN THE 769 00:32:15,669 --> 00:32:19,306 END, IT DID, FOR ME, RESONATE 770 00:32:19,306 --> 00:32:21,809 THIS FEELING OF, HEY, WE WERE 771 00:32:21,809 --> 00:32:25,846 THINKING ALONG THOSE LINES 772 00:32:25,846 --> 00:32:26,480 ANYWAY. 773 00:32:26,480 --> 00:32:27,281 YOU KNOW, IMPLEMENTATION GOALS 774 00:32:27,281 --> 00:32:28,015 REMAIN FIRM. 775 00:32:28,015 --> 00:32:32,820 WE HAD THAT IN OUR STRATEGIC 776 00:32:32,820 --> 00:32:33,954 PLAN, IN 2020. 777 00:32:33,954 --> 00:32:35,055 WE HAVE THAT IN PLACE. 778 00:32:35,055 --> 00:32:37,324 MOST OF YOU HAVE READ IT. 779 00:32:37,324 --> 00:32:39,093 WE DO ASK THESE SPECIFIC 780 00:32:39,093 --> 00:32:42,229 QUESTIONS, I'M LEAVING THEM AS 781 00:32:42,229 --> 00:32:44,198 OPEN-ENDED QUESTIONS, NOT ALL 782 00:32:44,198 --> 00:32:44,698 ENCOMPASSING. 783 00:32:44,698 --> 00:32:46,734 COUNCIL, I WILL COUNT ON YOU TO 784 00:32:46,734 --> 00:32:48,469 HELP US MOVE THIS THROUGH 785 00:32:48,469 --> 00:32:51,672 BECAUSE AS WE LOOK THROUGH 786 00:32:51,672 --> 00:32:54,742 PORTFOLIOS, LOOK TO THE DATA IN 787 00:32:54,742 --> 00:32:56,243 THAT EXECUTIVE SUMMARY, AND 788 00:32:56,243 --> 00:32:58,512 RECOGNIZE THAT DESPITE OUR 789 00:32:58,512 --> 00:33:04,919 SCIENCE AND LESSONS IN SCIENCE, 790 00:33:04,919 --> 00:33:08,022 AN EXAMPLE, WE'VE INVESTED 791 00:33:08,022 --> 00:33:11,025 HEAVILY OVER ALL 75 YEARS WE 792 00:33:11,025 --> 00:33:11,525 STILL HAVE DISADVANTAGED 793 00:33:11,525 --> 00:33:13,127 COMMUNITIES, FOUR OUT OF FIVE 794 00:33:13,127 --> 00:33:14,862 CHILDREN WITH UNTREATED DECAY IN 795 00:33:14,862 --> 00:33:18,165 THIS COUNTRY, THAT WE HAVE TO BE 796 00:33:18,165 --> 00:33:21,402 LOOKING AT WHAT WE NEED TO DO 797 00:33:21,402 --> 00:33:25,406 BETTER, THE OPPORTUNITIES. 798 00:33:25,406 --> 00:33:27,675 SO, HOW DO WE IMPROVE CLINICAL 799 00:33:27,675 --> 00:33:30,945 RESEARCH CAPABILITIES IN THE 800 00:33:30,945 --> 00:33:31,145 FIELD? 801 00:33:31,145 --> 00:33:32,479 WE JUST DON'T HAVE ENOUGH. 802 00:33:32,479 --> 00:33:35,416 I MEAN, THAT'S THE WAY AANALYZE. 803 00:33:35,416 --> 00:33:38,285 YOU SEE AWARDS WE FUND. 804 00:33:38,285 --> 00:33:39,486 IT'S NOT THAT WE'RE IGNORING IT 805 00:33:39,486 --> 00:33:41,889 BUT WE DON'T HAVE THE CRITICAL 806 00:33:41,889 --> 00:33:50,331 MASS OR ASSOCIATIONS TO MOVE THE 807 00:33:50,331 --> 00:33:54,969 NEEDLE IN CLINICAL TRIALS 808 00:33:54,969 --> 00:33:57,471 RESEARCH AS A SUBSET. 809 00:33:57,471 --> 00:33:59,540 HOW DO WE ENCOURAGE TRANSLATION, 810 00:33:59,540 --> 00:34:01,075 IMPROVE NUMBER OF CLINICAL 811 00:34:01,075 --> 00:34:01,976 TRIALS AND OBSERVATIONAL 812 00:34:01,976 --> 00:34:05,779 RESEARCH CAPABILITIES? 813 00:34:05,779 --> 00:34:08,282 HOW DO DENTAL SCHOOLS THROUGH 814 00:34:08,282 --> 00:34:09,516 ANY MECHANISM ACTUALLY BECOME 815 00:34:09,516 --> 00:34:11,485 THE HUB FOR TESTING NEW DENTAL 816 00:34:11,485 --> 00:34:13,254 MATERIALS AND DEVELOPING THEM AS 817 00:34:13,254 --> 00:34:13,654 WELL? 818 00:34:13,654 --> 00:34:18,359 HOW DO WE INCLUDE COMMUNITIES 819 00:34:18,359 --> 00:34:20,327 CURRENTLY MARGINALIZED IN A MUCH 820 00:34:20,327 --> 00:34:21,228 MORE ORGANIZED WAY. 821 00:34:21,228 --> 00:34:28,135 JENNIFER WILL HAVE MORE ON THAT. 822 00:34:28,135 --> 00:34:29,303 NOW, DR. BERTAGNOLLI'S THOUGHTS 823 00:34:29,303 --> 00:34:31,939 FOCUS ON NEED TO BRING THANS 824 00:34:31,939 --> 00:34:33,574 FORMATION TO PRIMARY CARE 825 00:34:33,574 --> 00:34:34,008 FACILITIES. 826 00:34:34,008 --> 00:34:35,776 WHO BETTER THAN DENTAL 827 00:34:35,776 --> 00:34:36,076 COMMUNITIES? 828 00:34:36,076 --> 00:34:37,845 AND OUR DENTAL SCHOOLS THAT 829 00:34:37,845 --> 00:34:40,581 SERVE AS MAJOR SAFETY NET FOR 830 00:34:40,581 --> 00:34:41,015 PROVIDERS? 831 00:34:41,015 --> 00:34:46,387 I SEE HUGE OPPORTUNITIES TO EVEN 832 00:34:46,387 --> 00:34:47,254 ATTEMPT TO COMBINE ELECTRONIC 833 00:34:47,254 --> 00:34:49,023 HEALTH RECORDS AND COORDINATE 834 00:34:49,023 --> 00:34:50,324 ACROSS OUR CLINORIL RESEARCH 835 00:34:50,324 --> 00:34:50,557 NETWORK. 836 00:34:50,557 --> 00:34:54,495 WE CAN'T JUST DO IT WITH THOSE 837 00:34:54,495 --> 00:34:56,163 FOCUSED ON BEHAVIORAL 838 00:34:56,163 --> 00:34:57,431 CONDITIONING WITH CHILD CARIES. 839 00:34:57,431 --> 00:34:59,433 WE HAVE TO KNOW THERE ARE 840 00:34:59,433 --> 00:35:01,268 PEDIATRIC NETWORKS THAT HEART 841 00:35:01,268 --> 00:35:03,804 AND LUNG NETWORKS, DIABETES 842 00:35:03,804 --> 00:35:05,005 NETWORKS, ACROSS THE COUNTRY, 843 00:35:05,005 --> 00:35:06,640 CHILD HEALTH AND HUMAN 844 00:35:06,640 --> 00:35:07,274 DEVELOPMENT WHERE ORAL HEALTH, 845 00:35:07,274 --> 00:35:09,810 THE PRESENCE OF ORAL HEALTH IS 846 00:35:09,810 --> 00:35:11,578 GOING TO BE ABSOLUTELY 847 00:35:11,578 --> 00:35:12,313 TRANSFORMATIVE. 848 00:35:12,313 --> 00:35:18,886 WE'RE GOING TO BE TALKING TO YOU 849 00:35:18,886 --> 00:35:21,755 FAR MORE IN MAY IN PERSON, WE'LL 850 00:35:21,755 --> 00:35:25,025 HAVE THAT OPPORTUNITY TO 851 00:35:25,025 --> 00:35:26,460 BRAINSTORM IDEAS AROUND THIS, TO 852 00:35:26,460 --> 00:35:29,530 THE BENEFIT OF TRAINEES AND 853 00:35:29,530 --> 00:35:30,497 FACULTY FOR SURE. 854 00:35:30,497 --> 00:35:32,132 KEEP THESE QUESTIONS IN MIND. 855 00:35:32,132 --> 00:35:33,901 THINK ABOUT WHAT YOU'RE DOING IN 856 00:35:33,901 --> 00:35:34,668 THIS SPACE. 857 00:35:34,668 --> 00:35:37,938 IN OUR SPACE, WE ARE FUNDING 858 00:35:37,938 --> 00:35:39,873 CLINICAL RESEARCH IN THESE TOPIC 859 00:35:39,873 --> 00:35:40,174 AREAS. 860 00:35:40,174 --> 00:35:41,775 THEY ARE BROAD BASED AND 861 00:35:41,775 --> 00:35:44,378 DIVERSE, THEY COVER MOST OF OUR 862 00:35:44,378 --> 00:35:47,681 SPECTRUM, MOST OF OUR RESEARCH 863 00:35:47,681 --> 00:35:47,948 PORTFOLIO. 864 00:35:47,948 --> 00:35:51,285 YOU CAN SEE WE HAVE A TOTAL OF 865 00:35:51,285 --> 00:35:53,287 43 CLINICAL TRIALS THAT WE'RE 866 00:35:53,287 --> 00:35:55,222 FUNDING ACROSS THE SPECTRUM. 867 00:35:55,222 --> 00:35:57,658 THREE ARE ACTUALLY CO-FUNDED IN 868 00:35:57,658 --> 00:35:58,792 THE AREA OF CRANIOFACIAL 869 00:35:58,792 --> 00:36:00,260 ANOMALIES, IN THE AREA OF HEAD 870 00:36:00,260 --> 00:36:02,329 AND NECK CANCER. 871 00:36:02,329 --> 00:36:04,531 WE HAVE THREE THERE. 872 00:36:04,531 --> 00:36:07,601 THREE THAT ARE PRACTICE-BASED 873 00:36:07,601 --> 00:36:08,369 RESEARCH NETWORKS, 874 00:36:08,369 --> 00:36:11,772 PRACTICE-BASED RESEARCH NETWORK 875 00:36:11,772 --> 00:36:12,239 IS FUNDING. 876 00:36:12,239 --> 00:36:14,808 ANY ONE OF THE P.I.s IN THESE 877 00:36:14,808 --> 00:36:17,111 AWARDS, ASK IF THEY ARE 878 00:36:17,111 --> 00:36:19,546 CONNECTED TO OTHER LARGE TRIALS, 879 00:36:19,546 --> 00:36:22,349 WORKING ON OTHER HEALTH ISSUES 880 00:36:22,349 --> 00:36:28,055 THAT IMPLICATE ORAL HEALTH, YOU 881 00:36:28,055 --> 00:36:29,022 WON'T FIND THE RESONATING YET 882 00:36:29,022 --> 00:36:30,023 BECAUSE WE DON'T HAVE THE 883 00:36:30,023 --> 00:36:31,458 INFRASTRUCTURE TO PRESENT TO 884 00:36:31,458 --> 00:36:33,193 THIS GROUP SO WE NEED TO 885 00:36:33,193 --> 00:36:33,527 ADVANCE. 886 00:36:33,527 --> 00:36:36,797 SARAH, I'LL ASK FOR YOUR HELP IN 887 00:36:36,797 --> 00:36:38,599 DOING SO. 888 00:36:38,599 --> 00:36:41,168 THE OTHER IMPLICATION OR GUIDING 889 00:36:41,168 --> 00:36:43,370 PRINCIPLE THAT DR. BERTAGNOLLI 890 00:36:43,370 --> 00:36:45,439 BROUGHT UP TIMELY AND 891 00:36:45,439 --> 00:36:47,441 SIGNIFICANT, VERY EXPENSIVE, 892 00:36:47,441 --> 00:36:50,277 VERY AMBITIOUS, BUT MEETING THAT 893 00:36:50,277 --> 00:36:52,679 FOCUS AND THAT RESOLVE, IS 894 00:36:52,679 --> 00:36:54,748 RELATED TO OUR CAPABILITIES AND 895 00:36:54,748 --> 00:36:56,884 CAPACITY FOR DATA SHARING AND 896 00:36:56,884 --> 00:36:57,584 DATA USE. 897 00:36:57,584 --> 00:37:01,221 I'M NOT GOING TO SAY MORE. 898 00:37:01,221 --> 00:37:03,957 YOU KNOW WE TOOK -- WE WERE 899 00:37:03,957 --> 00:37:06,927 PRO-ACTIVE IN THIS AREA, AND 900 00:37:06,927 --> 00:37:09,163 AXEL VISEL AND HIS GROUP OF 901 00:37:09,163 --> 00:37:11,198 NATIONAL EXPERTS WORKED OVER THE 902 00:37:11,198 --> 00:37:13,834 LAST ALMOST TWO YEARS, WILL BE 903 00:37:13,834 --> 00:37:16,203 PRESENTING ON THEIR FINDINGS. 904 00:37:16,203 --> 00:37:18,172 WE'LL TAKE THAT, PRIORITIZE 905 00:37:18,172 --> 00:37:21,542 THEIR RECOMMENDATIONS WITH YOUR 906 00:37:21,542 --> 00:37:22,709 HELP WITH COUNCIL'S HELP. 907 00:37:22,709 --> 00:37:27,514 IT WILL GUIDE THE VISION FOR NEW 908 00:37:27,514 --> 00:37:30,451 OFFICE OF DATA-DRIVEN SOLUTIONS, 909 00:37:30,451 --> 00:37:32,419 DDS, TO ADVANCE THESE GOALS. 910 00:37:32,419 --> 00:37:36,690 YOU CAN SEE IT BRINGS IN 911 00:37:36,690 --> 00:37:38,025 RESOURCES, FACTORS IN 912 00:37:38,025 --> 00:37:38,759 COLLABORATION, OF COURSE 913 00:37:38,759 --> 00:37:41,829 LEVERAGING AS MUCH AS WE CAN 914 00:37:41,829 --> 00:37:44,465 WHAT'S AVAILABLE IN AND OUTSIDE 915 00:37:44,465 --> 00:37:44,631 NIH. 916 00:37:44,631 --> 00:37:46,967 THESE ARE OUR DATA SCIENCE TOPIC 917 00:37:46,967 --> 00:37:49,269 AREAS, AS YOU CAN SEE, WE REALLY 918 00:37:49,269 --> 00:37:52,005 ALSO COVER QUITE A FEW, BUT NOT 919 00:37:52,005 --> 00:37:52,172 ALL. 920 00:37:52,172 --> 00:37:57,277 AND WE HAVE HERE IN THIS 921 00:37:57,277 --> 00:37:59,112 BEAUTIFUL DIAGRAM SCHEMATIC THE 922 00:37:59,112 --> 00:38:01,148 SPECIFIC FOCUS AREAS WHERE WE'RE 923 00:38:01,148 --> 00:38:02,449 FUNDING DATA SCIENCE 924 00:38:02,449 --> 00:38:02,749 INITIATIVES. 925 00:38:02,749 --> 00:38:04,718 NOW, IF YOU'RE INVOLVED IN ANY 926 00:38:04,718 --> 00:38:06,253 OF THE MAJOR COLLABORATIVES YOU 927 00:38:06,253 --> 00:38:08,989 WOULD KNOW IMMEDIATELY THAT DATA 928 00:38:08,989 --> 00:38:10,858 SCIENCE BECOMES THE NEW NORM. 929 00:38:10,858 --> 00:38:11,959 IT JUST IS. 930 00:38:11,959 --> 00:38:15,362 WE'LL HAVE TO BE THINKING FROM 931 00:38:15,362 --> 00:38:17,231 GROUND ZERO INCORPORATING DATA 932 00:38:17,231 --> 00:38:19,399 SCIENCE PRINCIPLES, THE FAIR 933 00:38:19,399 --> 00:38:19,867 PRINCIPLES. 934 00:38:19,867 --> 00:38:22,569 SO FOR NOW, WE'RE MAKING SURE 935 00:38:22,569 --> 00:38:24,204 THAT ALL OUR EXECUTIVE STAFF, WE 936 00:38:24,204 --> 00:38:27,875 CAN WRAP OUR HEADS AROUND THIS 937 00:38:27,875 --> 00:38:30,377 FIELD THAT IS CHANGING, AND 938 00:38:30,377 --> 00:38:31,478 THERE ARE GENERATIONAL 939 00:38:31,478 --> 00:38:35,415 CHALLENGES THAT I FACE, I 940 00:38:35,415 --> 00:38:40,821 MYSELF, SO WE CAN MOVE THE 941 00:38:40,821 --> 00:38:42,756 INSTITUTE FORWARD IN THIS 942 00:38:42,756 --> 00:38:44,391 DIRECTION AND MAKE ORAL DISEASE 943 00:38:44,391 --> 00:38:45,259 AND DISORDERS MUCH MORE 944 00:38:45,259 --> 00:38:48,228 RESOLVABLE IN MANY WAYS USING 945 00:38:48,228 --> 00:38:49,196 THIS NEW TECHNOLOGY. 946 00:38:49,196 --> 00:38:52,065 THIS IS THE EXCITING PART OF THE 947 00:38:52,065 --> 00:38:52,499 PRESENTATION. 948 00:38:52,499 --> 00:38:55,002 I WILL GO THROUGH BRIEFLY 949 00:38:55,002 --> 00:38:56,303 BECAUSE THERE'S A SCIENTIFIC 950 00:38:56,303 --> 00:38:57,204 DETAIL THAT I CAN TALK, YOU 951 00:38:57,204 --> 00:38:59,706 KNOW, I DON'T HAVE TIME TO TALK 952 00:38:59,706 --> 00:39:00,040 ABOUT. 953 00:39:00,040 --> 00:39:02,109 BUT THRILLED TO SAY THAT IN THIS 954 00:39:02,109 --> 00:39:05,612 LAST YEAR AND YOU HEARD ABOUT 955 00:39:05,612 --> 00:39:07,814 THIS LAST COUNCIL, BUT I'LL GIVE 956 00:39:07,814 --> 00:39:09,650 MORE DETAILS I CAN NOW SHARE. 957 00:39:09,650 --> 00:39:12,486 WE LAUNCHED THESE INITIATIVES TO 958 00:39:12,486 --> 00:39:16,990 SIGNIFY OUR COMMITMENT AND 959 00:39:16,990 --> 00:39:18,425 RECOGNITION OF OUR 75 YEARS OF 960 00:39:18,425 --> 00:39:22,296 HISTORY BRINGING THE HOPE AND 961 00:39:22,296 --> 00:39:24,364 PROMISE NEXT 25 YEARS WILL MOVE 962 00:39:24,364 --> 00:39:25,699 THE NEEDLE FORWARD. 963 00:39:25,699 --> 00:39:27,401 EACH INITIATIVE IS 964 00:39:27,401 --> 00:39:28,835 TRANSFORMATIVE. 965 00:39:28,835 --> 00:39:29,836 BOTTOM THREE IN COLLABORATION 966 00:39:29,836 --> 00:39:34,508 WITH PAIN AND PAIN MANAGEMENT, 967 00:39:34,508 --> 00:39:36,376 AS WELL AS SJOGREN'S THEME 968 00:39:36,376 --> 00:39:39,446 EFFORT THAT'S A NATIONWIDE 969 00:39:39,446 --> 00:39:40,981 COLLABORATIVE WITH NIAMS AND 970 00:39:40,981 --> 00:39:43,083 OTHER INSTITUTES AS WELL AS 971 00:39:43,083 --> 00:39:45,485 CENTERED AT UCSF, THE OKLAHOMA 972 00:39:45,485 --> 00:39:47,220 FOUNDATION, JOHNS HOPKINS, AND 973 00:39:47,220 --> 00:39:50,624 OF COURSE OUR CADRE OF 974 00:39:50,624 --> 00:39:54,127 RESEARCHERS AT NIDCR WHO HAVE 975 00:39:54,127 --> 00:39:56,697 ESTABLISHED A FOUNDATIONAL BASE 976 00:39:56,697 --> 00:39:59,299 FOR SALIVARY GLAND BIOLOGY. 977 00:39:59,299 --> 00:40:02,336 INTERESTINGLY ENOUGH ALL THESE 978 00:40:02,336 --> 00:40:05,172 ACRONYMS, AIM, AT THE BOTTOM 979 00:40:05,172 --> 00:40:11,011 RIGHT, TO HEAL, THE TWO PURPLE 980 00:40:11,011 --> 00:40:13,313 INITIATIVES, PRIME IS IN DENTAL 981 00:40:13,313 --> 00:40:16,483 SCHOOL, HEAD WITH CANCER, IMPACT 982 00:40:16,483 --> 00:40:18,018 WITH TEMPOROMANDIBULAR JOINT, IT 983 00:40:18,018 --> 00:40:20,220 MAKES A SENTENCE THAT IS 984 00:40:20,220 --> 00:40:21,288 SIGNIFICANT FOR OUR 75th. 985 00:40:21,288 --> 00:40:25,125 SO AS YOU ALL KNOW THE 986 00:40:25,125 --> 00:40:26,126 PRACTICE-BASED NETWORK IN DENTAL 987 00:40:26,126 --> 00:40:28,862 SCHOOLS HAS A VERY NOBLE GOAL OF 988 00:40:28,862 --> 00:40:30,831 CHANGING THE CULTURE TO ITS 989 00:40:30,831 --> 00:40:34,434 RESEARCH DONE IN DENTAL SCHOOL. 990 00:40:34,434 --> 00:40:35,969 IT ENGAGES FACULTY AND 991 00:40:35,969 --> 00:40:39,139 ADMINISTRATORS, STUDENTS AT ALL 992 00:40:39,139 --> 00:40:41,108 LEVELS OF TRAINING, LEVERAGES 993 00:40:41,108 --> 00:40:45,145 FROM RESOURCES OF THE MEDICAL 994 00:40:45,145 --> 00:40:46,747 SCHOOL, MOSTLY CDSAs, PUBLIC 995 00:40:46,747 --> 00:40:47,881 HEALTH, SCHOOL OF PHARMACY. 996 00:40:47,881 --> 00:40:50,617 YOU CAN SEE IF IT DOES TAKE OFF 997 00:40:50,617 --> 00:40:52,486 LIKE THEY ARE HOPING IT'S JUST 998 00:40:52,486 --> 00:40:57,324 GOING TO LIGHT THAT MATCH SO 999 00:40:57,324 --> 00:41:01,461 THAT MORE GRANTS COME FORTH FROM 1000 00:41:01,461 --> 00:41:03,130 PRIMED. 1001 00:41:03,130 --> 00:41:04,631 THRILLED WE COULD FUND TEN 1002 00:41:04,631 --> 00:41:06,366 ACROSS THE COUNTRY, IT'S LIKE A 1003 00:41:06,366 --> 00:41:07,901 DREAM COME TRUE BECAUSE THEY 1004 00:41:07,901 --> 00:41:09,803 INVOLVE SCHOOLS THAT ARE NOT 1005 00:41:09,803 --> 00:41:10,904 HEAVILY RESOURCED IN THE 1006 00:41:10,904 --> 00:41:12,039 RESEARCH AREA BUT ARE 1007 00:41:12,039 --> 00:41:13,173 COLLABORATING WITH THOSE THAT 1008 00:41:13,173 --> 00:41:13,507 ARE. 1009 00:41:13,507 --> 00:41:16,343 AS WELL AS THOSE THAT HAVE VERY 1010 00:41:16,343 --> 00:41:17,778 WELL-ESTABLISHED PROGRAMS. 1011 00:41:17,778 --> 00:41:22,049 YOU CAN SEE FROM HERE, THE 1012 00:41:22,049 --> 00:41:24,885 BREADTH OF INQUIRY OF THIS 1013 00:41:24,885 --> 00:41:26,086 CLINICAL RESEARCH THAT FITS SO 1014 00:41:26,086 --> 00:41:30,590 WELL INTO OUR EFFORTS TO CREATE 1015 00:41:30,590 --> 00:41:31,992 THAT WORKFORCE THAT PERHAPS A 1016 00:41:31,992 --> 00:41:32,859 CLINICAL TRIALS RESEARCH NETWORK 1017 00:41:32,859 --> 00:41:35,395 THAT COULD BE BASED IN DENTAL 1018 00:41:35,395 --> 00:41:37,030 SCHOOLS AS WELL. 1019 00:41:37,030 --> 00:41:38,799 SO, JUST WE SHOULD BE TAKING 1020 00:41:38,799 --> 00:41:41,334 ADVANTAGE OF ALL THAT IS 1021 00:41:41,334 --> 00:41:43,170 AVAILABLE HERE, DATA SCIENCE, 1022 00:41:43,170 --> 00:41:48,642 AND CLINICAL RESEARCH 1023 00:41:48,642 --> 00:41:50,377 METHODOLOGY PRINCIPLES. 1024 00:41:50,377 --> 00:41:53,780 IT'S EASY TO FLASH A SLIDE, BUT 1025 00:41:53,780 --> 00:41:56,383 STAFF WORKED TIRELESSLY TO MAKE 1026 00:41:56,383 --> 00:41:58,051 THIS POSSIBLE. 1027 00:41:58,051 --> 00:41:59,486 DENA FISCHER, A HUGE THANKS. 1028 00:41:59,486 --> 00:42:01,088 YOU'RE THE PILLAR OF SUPPORT IN 1029 00:42:01,088 --> 00:42:02,989 THIS AREA. 1030 00:42:02,989 --> 00:42:11,965 YOUR STAFF AND TEAM, SCIENTIFIC 1031 00:42:11,965 --> 00:42:13,366 REVIEW BRANCH, AND DEDE 1032 00:42:13,366 --> 00:42:14,034 RUTHBERG. 1033 00:42:14,034 --> 00:42:17,404 THE PROGRAM IS CHALLENGING TO 1034 00:42:17,404 --> 00:42:19,406 MANAGE AND TO KIND OF KEEP GOING 1035 00:42:19,406 --> 00:42:20,674 IN THE RIGHT DIRECTION, YOU 1036 00:42:20,674 --> 00:42:23,343 WOULD IMAGINE, BECAUSE OF THE 1037 00:42:23,343 --> 00:42:24,778 DIVERSITY LEVELS OF EXPERIENCE 1038 00:42:24,778 --> 00:42:26,880 AND INTEREST ACROSS THE COUNTRY. 1039 00:42:26,880 --> 00:42:29,649 WE'RE THRILLED TO BE 1040 00:42:29,649 --> 00:42:30,317 COLLABORATING WITH WITH NATIONAL 1041 00:42:30,317 --> 00:42:32,018 CANCER INSTITUTE TO DEVELOP 1042 00:42:32,018 --> 00:42:32,986 BIOMARKERS THAT DETECT EARLY 1043 00:42:32,986 --> 00:42:34,621 DETECTION OF HEAD AND NECK 1044 00:42:34,621 --> 00:42:34,988 CANCER. 1045 00:42:34,988 --> 00:42:39,025 WE JUST DON'T HAVE ANY. 1046 00:42:39,025 --> 00:42:40,861 HERE WE HAVE SEVEN OUTSTANDING 1047 00:42:40,861 --> 00:42:42,429 GROUPS OF RESEARCHERS THAT 1048 00:42:42,429 --> 00:42:43,296 THEMSELVES ARE COLLABORATING 1049 00:42:43,296 --> 00:42:45,599 WITH OTHER GROUPS AROUND THE 1050 00:42:45,599 --> 00:42:45,832 COUNTRY. 1051 00:42:45,832 --> 00:42:47,234 WE EXPECT THINGS TO HAPPEN IN 1052 00:42:47,234 --> 00:42:47,868 THIS AREA. 1053 00:42:47,868 --> 00:42:55,675 THERE'S A LOT IN THE AREA OF 1054 00:42:55,675 --> 00:42:56,576 FACIAL TRANSCRIPTOMICS, 1055 00:42:56,576 --> 00:42:58,912 SINGLE-CELL DATA LINKED TO 1056 00:42:58,912 --> 00:42:59,613 POPULATION SCIENCE AND 1057 00:42:59,613 --> 00:43:00,313 PREVENTION. 1058 00:43:00,313 --> 00:43:03,016 THIS SHOULD MOVE THE NEEDLE 1059 00:43:03,016 --> 00:43:03,450 THERE. 1060 00:43:03,450 --> 00:43:07,954 AGAIN, MANY THANKS TO DR. CHEN 1061 00:43:07,954 --> 00:43:09,055 AND HER GROUP, AMANDA, LILLIAN 1062 00:43:09,055 --> 00:43:11,925 OF COURSE, AND EVERYONE ELSE 1063 00:43:11,925 --> 00:43:13,093 THAT MADE THIS POSSIBLE. 1064 00:43:13,093 --> 00:43:19,332 HARD TO NOT BE EXCITED ABOUT TMD 1065 00:43:19,332 --> 00:43:21,434 IMPACT, SO MUCH LED TO 1066 00:43:21,434 --> 00:43:23,804 INITIATIVE, SUPPORT, VISION AND 1067 00:43:23,804 --> 00:43:26,673 DRIVE COMING IN FROM TERRY AND 1068 00:43:26,673 --> 00:43:28,408 THE TMJ ASSOCIATION CANNOT BE 1069 00:43:28,408 --> 00:43:28,875 IGNORED. 1070 00:43:28,875 --> 00:43:31,645 THAT CAME TOGETHER WITH PARTNERS 1071 00:43:31,645 --> 00:43:32,479 FROM DIFFERENT INSTITUTES TO 1072 00:43:32,479 --> 00:43:37,050 HELP US MOVE FROM PLANNING PHASE 1073 00:43:37,050 --> 00:43:38,585 TO IMPLEMENTATION PHASE SOON TO 1074 00:43:38,585 --> 00:43:39,486 COME. 1075 00:43:39,486 --> 00:43:41,788 WE HAVE ANOTHER OUTSTANDING 1076 00:43:41,788 --> 00:43:42,422 GROUP, MINI CENTERS. 1077 00:43:42,422 --> 00:43:43,723 THEY WILL BE TALKING TO EACH 1078 00:43:43,723 --> 00:43:44,324 OTHER. 1079 00:43:44,324 --> 00:43:46,259 IT'S NOT LIKE THE OLD DAYS. 1080 00:43:46,259 --> 00:43:48,428 THEY WILL BE TALKING TO EACH 1081 00:43:48,428 --> 00:43:51,598 OTHER, SHARING RESOURCES, BEST 1082 00:43:51,598 --> 00:43:53,366 PRACTICES, FAILURES, ALL OF 1083 00:43:53,366 --> 00:43:53,900 THAT. 1084 00:43:53,900 --> 00:43:54,968 WE'LL BE CREATING THIS COMMUNITY 1085 00:43:54,968 --> 00:43:56,236 WITHIN THE COMMUNITY TO MAKE THE 1086 00:43:56,236 --> 00:44:01,808 VERY BEST OF WHAT WE HAVE. 1087 00:44:01,808 --> 00:44:03,877 THE TEAM AGAIN FOR THIS EFFORT 1088 00:44:03,877 --> 00:44:05,212 WITH AMANDA AND LILLIAN HAVE 1089 00:44:05,212 --> 00:44:06,313 BEEN TREMENDOUS. 1090 00:44:06,313 --> 00:44:08,181 WE WORK WITH OTHER INDIVIDUALS 1091 00:44:08,181 --> 00:44:10,050 FROM OTHER INSTITUTES WHO ARE 1092 00:44:10,050 --> 00:44:14,888 VERY KIND IN OFFERING DIRECTION 1093 00:44:14,888 --> 00:44:16,990 AND ADVICE. 1094 00:44:16,990 --> 00:44:19,159 SO NOW AS YOU KNOW 80% OF 1095 00:44:19,159 --> 00:44:21,127 FUNDING GOES TO EXTRAMURAL 1096 00:44:21,127 --> 00:44:21,628 COMMUNITY. 1097 00:44:21,628 --> 00:44:23,997 IT'S REALLY IMPOSSIBLE TO 1098 00:44:23,997 --> 00:44:26,566 SUMMARIZE ALL THE PAPERS FROM 1099 00:44:26,566 --> 00:44:27,467 THESE INVESTMENTS. 1100 00:44:27,467 --> 00:44:30,537 I HAVE TEN SLIDES THAT QUICKLY 1101 00:44:30,537 --> 00:44:33,173 WILL GLANCE AND GIVE A SENSE 1102 00:44:33,173 --> 00:44:35,675 THAT OUR FOUNDATIONAL SCIENCES 1103 00:44:35,675 --> 00:44:37,777 ARE MOVING, TRANSLATIONAL IS 1104 00:44:37,777 --> 00:44:38,979 DEVELOPING WELL, AND CLINICAL 1105 00:44:38,979 --> 00:44:40,947 RESEARCH IS IN THE PHASE OF 1106 00:44:40,947 --> 00:44:42,115 DEVELOPING. 1107 00:44:42,115 --> 00:44:50,357 WE HAVE THESE EXAMPLES HERE TO 1108 00:44:50,357 --> 00:44:53,226 SHOW SECRETORY FUNCTIONS, YOU 1109 00:44:53,226 --> 00:44:55,195 CAN UNDERSTAND HOW SECRETORY 1110 00:44:55,195 --> 00:44:59,132 MECHANISMS AND SECRETION AND IN 1111 00:44:59,132 --> 00:45:01,201 SALIVA PRODUCTION OCCURS. 1112 00:45:01,201 --> 00:45:07,874 IMPORTANT STUDY ON CONSTRUCTING 1113 00:45:07,874 --> 00:45:10,744 A MICROTISSUE PLATFORM ALLOWING 1114 00:45:10,744 --> 00:45:14,347 FOR VASCULARIZATION, ENHANCING 1115 00:45:14,347 --> 00:45:17,951 HEALING AND THIS IS I THINK -- 1116 00:45:17,951 --> 00:45:18,952 YES, FROM PORTLAND, OHSU, HAS 1117 00:45:18,952 --> 00:45:21,221 BEEN A LEADER IN THIS FIELD OF 1118 00:45:21,221 --> 00:45:22,789 ORGANOID IN SILICO WORK AND 1119 00:45:22,789 --> 00:45:25,725 THINGS THAT CAN BE TRANSPLANTED 1120 00:45:25,725 --> 00:45:29,329 TO HUMANS TISSUES. 1121 00:45:29,329 --> 00:45:39,806 IN THIS CASE APICAL TISSUE, 1122 00:45:47,147 --> 00:45:47,948 PERIAPICAL TISSUES. 1123 00:45:47,948 --> 00:45:50,150 GINGIVALIS, VIEWED AS A VEHICLE 1124 00:45:50,150 --> 00:45:53,620 TO SERVE IN TRANSPORTING 1125 00:45:53,620 --> 00:45:54,220 ANTIMICROBIALS FOR THERAPEUTIC 1126 00:45:54,220 --> 00:45:58,458 PURPOSES, WHAT I CONSIDER IN THE 1127 00:45:58,458 --> 00:46:00,560 FIELD OF ENGINEERING. 1128 00:46:00,560 --> 00:46:04,731 WE HAD VERY NICE SET OF STUDIES 1129 00:46:04,731 --> 00:46:09,402 THAT LOOKED AT WHAT ARE THE 1130 00:46:09,402 --> 00:46:10,403 DIFFERENTIAL MARKERS OF PAIN, 1131 00:46:10,403 --> 00:46:11,371 MEN VERSUS WOMEN. 1132 00:46:11,371 --> 00:46:13,573 HERE IS AN EXAMPLE OF SOMETHING 1133 00:46:13,573 --> 00:46:16,977 THAT REALLY IS IN LINE WITH THE 1134 00:46:16,977 --> 00:46:17,978 PRESIDENTIAL INITIATIVE TO 1135 00:46:17,978 --> 00:46:19,679 FOSTER OR ADVANCE RESEARCH IN 1136 00:46:19,679 --> 00:46:23,016 WOMEN'S HEALTH. 1137 00:46:23,016 --> 00:46:24,117 THERE ARE DIFFERENCES IN GENES 1138 00:46:24,117 --> 00:46:25,719 BETWEEN MEN AND WOMEN. 1139 00:46:25,719 --> 00:46:27,587 WHEN YOU COMPARE TO CLINICAL 1140 00:46:27,587 --> 00:46:29,756 DATA THAT WE AS CLINICIANS HAVE 1141 00:46:29,756 --> 00:46:30,757 ENCOUNTERED, IT DOES MAKE SENSE 1142 00:46:30,757 --> 00:46:34,594 THAT THERE IS A DIFFERENCE IN 1143 00:46:34,594 --> 00:46:41,735 THE WAY WOMEN HANDLE PAIN, 1144 00:46:41,735 --> 00:46:43,903 MANAGE IT, TECHNICALLY, HOW THE 1145 00:46:43,903 --> 00:46:47,874 PROCESS UNFOLDS IN WOMEN VERSUS 1146 00:46:47,874 --> 00:46:48,441 MEN. 1147 00:46:48,441 --> 00:46:51,911 NOW LOOKING AT MEXICAN IMGRANTS 1148 00:46:51,911 --> 00:46:54,781 AND CENTRAL AMERICANS THE WAY WE 1149 00:46:54,781 --> 00:46:55,548 CAN INTRODUCE CULTURAL 1150 00:46:55,548 --> 00:46:57,751 COMPETENCES WHEN WE DEAL WITH 1151 00:46:57,751 --> 00:46:58,718 INDIVIDUALS FROM DIFFERENT 1152 00:46:58,718 --> 00:46:59,686 BACKGROUNDS WITH DIFFERENT 1153 00:46:59,686 --> 00:47:00,253 LANGUAGES PRIMARILY. 1154 00:47:00,253 --> 00:47:03,323 YOU CAN SEE THAT ROLE IS 1155 00:47:03,323 --> 00:47:10,764 POSITIVE AND INFLUENCES OUR CARE 1156 00:47:10,764 --> 00:47:11,364 DELIVERY. 1157 00:47:11,364 --> 00:47:13,099 NO DOUBT THE NATIONAL DENTAL 1158 00:47:13,099 --> 00:47:15,702 PRACTICE BASED RESEARCH NETWORK 1159 00:47:15,702 --> 00:47:16,936 THAT'S POSITIONED NOW TO 1160 00:47:16,936 --> 00:47:18,805 ENCOMPASS THE NEW PRINCIPLES I 1161 00:47:18,805 --> 00:47:21,408 JUST DESCRIBED, BUT THIS IS ONE 1162 00:47:21,408 --> 00:47:24,544 STUDY DONE IN THAT NETWORK TO 1163 00:47:24,544 --> 00:47:28,515 LOOK AT AVAILABILITY OF PATIENT 1164 00:47:28,515 --> 00:47:31,584 HEALTH, PATIENT CONTROL OF 1165 00:47:31,584 --> 00:47:32,252 TREATMENT AND FOLLOW-UP 1166 00:47:32,252 --> 00:47:35,622 TREATMENT, SO HISPANIC PATIENTS 1167 00:47:35,622 --> 00:47:36,956 HAD LOWER DENTIST-PATIENT 1168 00:47:36,956 --> 00:47:37,824 COMMUNICATION THAN NON-HISPANIC, 1169 00:47:37,824 --> 00:47:44,497 THAT I HOPE WILL CHANGE NOW THAT 1170 00:47:44,497 --> 00:47:46,900 WE KNOW THAT, PRESENT THAT IN 1171 00:47:46,900 --> 00:47:48,802 WAYS TO HOPEFULLY ENCOURAGE NEW 1172 00:47:48,802 --> 00:47:50,637 POLICIES ACROSS THE BOARD. 1173 00:47:50,637 --> 00:47:54,441 GWAS AND DATA STUDIES LOOKING AT 1174 00:47:54,441 --> 00:47:59,312 GENETICS HAS COME FROM THE ABCD 1175 00:47:59,312 --> 00:48:01,147 STUDY ACTUALLY INITIATED IN 1176 00:48:01,147 --> 00:48:04,050 NATIONAL INSTITUTES OF DENTAL -- 1177 00:48:04,050 --> 00:48:05,752 OR DRUG ABUSE, NORA VOLKOW AND I 1178 00:48:05,752 --> 00:48:08,254 TALKED ABOUT THIS, GENE LOCI 1179 00:48:08,254 --> 00:48:13,426 THAT AFFECT THE WAY THE CRANIUM 1180 00:48:13,426 --> 00:48:15,361 SHAPES AND AS YOU KNOW SHAPES 1181 00:48:15,361 --> 00:48:18,465 TOO FAST OR FUSES TOO FAST 1182 00:48:18,465 --> 00:48:24,671 BECAUSE YOU HAVE A MUTATION, 1183 00:48:24,671 --> 00:48:27,407 AGAIN FUNCTION OR LOSS OF 1184 00:48:27,407 --> 00:48:28,808 FUNCTION, YOU CAN END UP WITH 1185 00:48:28,808 --> 00:48:29,275 THIS. 1186 00:48:29,275 --> 00:48:30,577 JANICE AND GROUP IN CLINICAL 1187 00:48:30,577 --> 00:48:38,118 RESEARCH PROGRAM HAS COME UP 1188 00:48:38,118 --> 00:48:39,119 WITH MORPHOMETRICS TO LOOK AT 1189 00:48:39,119 --> 00:48:41,421 THE SKULL, THIS FITS IN TO THAT 1190 00:48:41,421 --> 00:48:44,691 RESOURCE AS WELL. 1191 00:48:44,691 --> 00:48:46,226 IF THEY COME TOGETHER IT WOULD 1192 00:48:46,226 --> 00:48:47,660 BE A NICE RESOURCE FOR 1193 00:48:47,660 --> 00:48:48,294 CLINICIANS. 1194 00:48:48,294 --> 00:48:51,831 WE HAVE A MODEL FOR PHENOTYPES, 1195 00:48:51,831 --> 00:48:54,234 DIFFERENT BASED ON WHICH SUTURE 1196 00:48:54,234 --> 00:48:54,734 IS EFFECTIVE. 1197 00:48:54,734 --> 00:49:03,109 THIS IS THE USE OF A.I. ACTUALLY 1198 00:49:03,109 --> 00:49:05,512 TO MODEL ABNORMALITIES IN 1199 00:49:05,512 --> 00:49:06,613 CRANIUM SHAPE AND FORMS 1200 00:49:06,613 --> 00:49:11,518 ACCURATELY, TO BE ABLE TO BE 1201 00:49:11,518 --> 00:49:13,086 USED WELL, ACCURATELY WELL, BY 1202 00:49:13,086 --> 00:49:17,524 CLINICIANS WHO HAVE TO MAKE 1203 00:49:17,524 --> 00:49:21,161 DECISIONS ABOUT SURGERY. 1204 00:49:21,161 --> 00:49:23,596 WE HAVE ELECTRONIC HEALTH 1205 00:49:23,596 --> 00:49:24,898 RECORDS DATABASE NOW 1206 00:49:24,898 --> 00:49:26,032 INCORPORATING INDIVIDUALS THAT 1207 00:49:26,032 --> 00:49:26,766 HAVE SJOGREN'S SYNDROME. 1208 00:49:26,766 --> 00:49:29,202 THIS IS DONE AT THE INDIANA 1209 00:49:29,202 --> 00:49:30,603 UNIVERSITY SCHOOL OF DENTISTRY. 1210 00:49:30,603 --> 00:49:33,640 YOU CAN SEE HERE THAT IN 1211 00:49:33,640 --> 00:49:35,074 ADDITION TO SJOGREN'S THERE'S 1212 00:49:35,074 --> 00:49:39,145 ASSOCIATION MADE WITH SYSTEMIC 1213 00:49:39,145 --> 00:49:41,214 LUPUS, AND ALSO ANOTHER 1214 00:49:41,214 --> 00:49:45,485 COMORBIDITY THAT MAY OR MAY NOT 1215 00:49:45,485 --> 00:49:47,020 INVOLVE AUTOIMMUNE DYSFUNCTION. 1216 00:49:47,020 --> 00:49:49,322 SO AS WE MOVE INTO WHAT COMES 1217 00:49:49,322 --> 00:49:50,924 FORTH, WHAT IS AVAILABLE NOW, WE 1218 00:49:50,924 --> 00:49:53,726 HAVE A FEW RESEARCH FUNDING 1219 00:49:53,726 --> 00:49:54,694 OPPORTUNITIES. 1220 00:49:54,694 --> 00:49:58,865 THIS ONE IN ETHICAL LEGAL AND 1221 00:49:58,865 --> 00:50:00,967 SOCIAL IMPLICATIONS, R03, 1222 00:50:00,967 --> 00:50:01,834 AVAILABLE AND ADMINISTERED 1223 00:50:01,834 --> 00:50:03,036 SUPPLEMENTS IN THIS AREA, 1224 00:50:03,036 --> 00:50:05,371 IMPORTANT AS WE MOVE INTO THE 1225 00:50:05,371 --> 00:50:11,277 DATA SCIENCE REALM WHERE WE HAVE 1226 00:50:11,277 --> 00:50:13,012 TO RESPECT PATIENT IDENTITIES, 1227 00:50:13,012 --> 00:50:15,949 HONOR DATABASES THAT IN FACT 1228 00:50:15,949 --> 00:50:16,849 INVOLVE PATIENTS. 1229 00:50:16,849 --> 00:50:18,918 THERE IS A NEW NOSI ON 1230 00:50:18,918 --> 00:50:20,453 APPLICATIONS OF DATA SCIENCE IN 1231 00:50:20,453 --> 00:50:22,222 TRANSLATIONAL, SO THIS IS A 1232 00:50:22,222 --> 00:50:23,623 GREAT OPPORTUNITY FOR EVERY ONE 1233 00:50:23,623 --> 00:50:28,328 OF YOU TO COLLABORATE IF YOU 1234 00:50:28,328 --> 00:50:31,831 HAVE SCHOOLS OF DATA SCIENCE ON 1235 00:50:31,831 --> 00:50:33,900 YOUR CAMPUS, GET TOGETHER SO WE 1236 00:50:33,900 --> 00:50:36,402 CAN ENRICH THE PIPELINE FOR THE 1237 00:50:36,402 --> 00:50:37,303 FUTURE, ESPECIALLY FOR TRAINEES 1238 00:50:37,303 --> 00:50:38,705 WHO CAN COME WITH DENTAL 1239 00:50:38,705 --> 00:50:41,908 BACKGROUNDS BUT HAVE THE 1240 00:50:41,908 --> 00:50:44,077 EXPERTISE OF DATA SCIENCES. 1241 00:50:44,077 --> 00:50:47,647 WE JUST ARE LACKING IN THAT 1242 00:50:47,647 --> 00:50:48,681 PIPELINE NOW AND NEED TO DEVELOP 1243 00:50:48,681 --> 00:50:50,950 THAT FOR THE FUTURE. 1244 00:50:50,950 --> 00:50:54,053 INVITING INPUT ON AUTOIMMUNE 1245 00:50:54,053 --> 00:50:55,021 DISEASES, AN ANNOUNCEMENT OUT 1246 00:50:55,021 --> 00:50:56,222 FOR THAT. 1247 00:50:56,222 --> 00:50:58,591 PLEASE KNOW THE DEADLINE FOR 1248 00:50:58,591 --> 00:51:00,827 RESPONSE IS MARCH 1. 1249 00:51:00,827 --> 00:51:03,429 I WANT TO BRING BACK TO YOUR 1250 00:51:03,429 --> 00:51:05,632 ATTENTION THE FACT THAT OUR 1251 00:51:05,632 --> 00:51:08,801 75th ANNIVERSARY IS DRAWING TO 1252 00:51:08,801 --> 00:51:09,035 A CLOSE. 1253 00:51:09,035 --> 00:51:12,739 IT WILL BE JUNE OF THIS YEAR. 1254 00:51:12,739 --> 00:51:13,840 IT'S MET MY EXPECTATIONS MORE 1255 00:51:13,840 --> 00:51:18,111 THAN I COULD HAVE EVER IMAGINED. 1256 00:51:18,111 --> 00:51:19,846 EVERY EVENT SURPASSING THE ONE 1257 00:51:19,846 --> 00:51:21,714 WE DID BEFORE NOT TO BRAG BUT 1258 00:51:21,714 --> 00:51:23,916 MEANT TO FOCUS ON SCIENCE, ON 1259 00:51:23,916 --> 00:51:25,752 OUR COMMUNITIES, ON OUR 1260 00:51:25,752 --> 00:51:26,886 STAKEHOLDERS, OUR PARTNERSHIPS 1261 00:51:26,886 --> 00:51:27,954 AND TRAINEES. 1262 00:51:27,954 --> 00:51:32,125 YOU CAN SEE THAT WE SPECIAL 1263 00:51:32,125 --> 00:51:32,992 ISSUE DUE OUT, CONGRESSIONAL 1264 00:51:32,992 --> 00:51:34,961 RESOLUTION WILL BE PASSED ON THE 1265 00:51:34,961 --> 00:51:37,697 FLOOR VERY SOON, AND ALL THESE 1266 00:51:37,697 --> 00:51:41,200 OTHER THINGS MADE IT A SPECIAL 1267 00:51:41,200 --> 00:51:43,269 YEAR FOR US, THE HIGHLIGHT OF 1268 00:51:43,269 --> 00:51:44,804 WHICH ARE SIGNATURE INITIATIVES 1269 00:51:44,804 --> 00:51:46,439 THAT WE LAUNCHED. 1270 00:51:46,439 --> 00:51:47,640 VERY THRILLED TRAINING SESSION 1271 00:51:47,640 --> 00:51:56,215 WAS A HUGE SUCCESS, INSPIRING 1272 00:51:56,215 --> 00:52:06,726 TALK BY ARDEM PATAPOUTIAN, HIS 1273 00:52:17,170 --> 00:52:19,205 DAD SAYS IF HE CAN DO IT, YOU 1274 00:52:19,205 --> 00:52:20,640 CAN DO IT. 1275 00:52:20,640 --> 00:52:21,407 HE FAILED KINDERGARTEN. 1276 00:52:21,407 --> 00:52:27,046 THAT WAS THE MOST INSPIRING 1277 00:52:27,046 --> 00:52:29,716 TAKEAWAY MESSAGE, JUST TO LET 1278 00:52:29,716 --> 00:52:32,652 YOU KNOW AND ENCOURAGE YOU TO 1279 00:52:32,652 --> 00:52:34,420 ATTEND THE MEETING IN MARCH IN 1280 00:52:34,420 --> 00:52:36,622 NEW ORLEANS, BECAUSE IT'S THE 1281 00:52:36,622 --> 00:52:44,130 TIME TO CELEBRATE OUR EXTRAMURAL 1282 00:52:44,130 --> 00:52:44,364 SCIENCE. 1283 00:52:44,364 --> 00:52:46,032 HOW DEVELOPED OVER 75 YEARS, 1284 00:52:46,032 --> 00:52:49,836 WHERE WE WANT TO GO WILL BE 1285 00:52:49,836 --> 00:52:51,938 TALKED ABOUT IN EACH SYMPOSIA. 1286 00:52:51,938 --> 00:52:54,240 THE TIME AND DETAILS ARE IN THE 1287 00:52:54,240 --> 00:52:54,674 PROGRAM. 1288 00:52:54,674 --> 00:52:56,642 TRY TO ATTEND BECAUSE ESPECIALLY 1289 00:52:56,642 --> 00:52:58,511 FOR TRAINEES, YOU KNOW HOW 1290 00:52:58,511 --> 00:53:02,882 IMPORTANT IT IS TO INVEST IN 1291 00:53:02,882 --> 00:53:04,183 THAT TRANSLATIONAL CONTINUUM AND 1292 00:53:04,183 --> 00:53:06,386 HOW IMPORTANT OUR SCIENCE IS FOR 1293 00:53:06,386 --> 00:53:07,687 ORAL HEALTH. 1294 00:53:07,687 --> 00:53:10,523 AND THE TOPICS WE PICKED WERE 1295 00:53:10,523 --> 00:53:13,726 STRATEGIC, THEY COVER OUR MAIN 1296 00:53:13,726 --> 00:53:15,027 FOCUS AREAS. 1297 00:53:15,027 --> 00:53:17,663 I NOW WANT TO END WELCOMING 1298 00:53:17,663 --> 00:53:18,297 JENNIFER BUT ALSO TO ALERT YOU 1299 00:53:18,297 --> 00:53:25,772 TO THE LAST IN OUR SERIES OF 1300 00:53:25,772 --> 00:53:26,739 CELEBRATIONS, CO-SPONSORED 1301 00:53:26,739 --> 00:53:28,141 SYMPOSIUM, HEART, LUNG AND BLOOD 1302 00:53:28,141 --> 00:53:35,481 INSTITUTE, THAT ALSO ARE 1303 00:53:35,481 --> 00:53:38,217 CELEBRATING THEIR 75th, ON THE 1304 00:53:38,217 --> 00:53:39,519 16th OF MAY. 1305 00:53:39,519 --> 00:53:42,588 TO STAY TOGETHER AND SHARE 1306 00:53:42,588 --> 00:53:43,990 KNOWLEDGE IS PROGRESS, TO WORK 1307 00:53:43,990 --> 00:53:45,558 TOGETHER IS SUCCESS IN ALL WE DO 1308 00:53:45,558 --> 00:53:46,659 AND STAND FOR. 1309 00:53:46,659 --> 00:53:49,595 I THANK YOU FOR THAT. 1310 00:53:49,595 --> 00:53:51,431 VERY HAPPILY INTRODUCE DR. 1311 00:53:51,431 --> 00:53:52,799 JENNIFER WEBSTER CYRIAQUE WHO 1312 00:53:52,799 --> 00:53:56,502 WILL END THIS TALK. 1313 00:53:56,502 --> 00:53:56,803 JENNIFER? 1314 00:53:56,803 --> 00:54:03,676 I'LL GET OUT OF MY SCREEN. 1315 00:54:03,676 --> 00:54:13,719 1316 00:54:21,627 --> 00:54:28,201 >> CAN EVERYONE SEE AND HEAR? 1317 00:54:28,201 --> 00:54:31,504 I THINK WE'RE WAITING FOR THE 1318 00:54:31,504 --> 00:54:32,705 PRESENTATION. 1319 00:54:32,705 --> 00:54:34,373 I'M SHARING NOW. 1320 00:54:34,373 --> 00:54:35,241 SHALL I TRY AGAIN? 1321 00:54:35,241 --> 00:54:38,578 CAN YOU HEAR ME? 1322 00:54:38,578 --> 00:54:42,048 >> CAN YOU SHARE ONE MORE TIME? 1323 00:54:42,048 --> 00:54:52,225 >> OKAY. 1324 00:55:12,445 --> 00:55:14,780 IT DOESN'T LOOK LIKE MY VIDEO IS 1325 00:55:14,780 --> 00:55:16,849 ENABLED BUT THAT'S OKAY. 1326 00:55:16,849 --> 00:55:19,485 THANK YOU, RENA. 1327 00:55:19,485 --> 00:55:20,686 OH, START MY VIDEO. 1328 00:55:20,686 --> 00:55:22,555 HOW ARE WE GOING TO GET TO ORAL 1329 00:55:22,555 --> 00:55:23,523 HEALTH FOR ALL? 1330 00:55:23,523 --> 00:55:25,925 WE NEED TO BUILD BELONGING 1331 00:55:25,925 --> 00:55:27,994 ACROSS INTERNAL AND EXTERNAL 1332 00:55:27,994 --> 00:55:28,294 WORK FORCES. 1333 00:55:28,294 --> 00:55:30,196 WE NEED TO BREAK BARRIERS, AN WE 1334 00:55:30,196 --> 00:55:32,365 NEED TO BUILD THE EVIDENCE BASE. 1335 00:55:32,365 --> 00:55:34,133 THESE ARE THREE AREAS THAT I'D 1336 00:55:34,133 --> 00:55:37,737 LIKE TO SHARE WITH YOU THAT WE 1337 00:55:37,737 --> 00:55:42,775 FOCUS ON AS WE MOVE TOWARDS 1338 00:55:42,775 --> 00:55:44,210 MOVEMENT ON ORAL HEALTH 1339 00:55:44,210 --> 00:55:44,877 DISPARITIES. 1340 00:55:44,877 --> 00:55:49,115 AND THAT IS THE INTERNAL 1341 00:55:49,115 --> 00:55:50,316 WORKFORCE, EXTERNAL WORKFORCE, 1342 00:55:50,316 --> 00:55:59,091 AND THE SCIENCE TO MOVE BEYOND 1343 00:55:59,091 --> 00:55:59,425 DISPARITIES. 1344 00:55:59,425 --> 00:56:01,594 HOW DO WE GET THERE? 1345 00:56:01,594 --> 00:56:04,797 FROM THE STANDPOINT OF OUR 1346 00:56:04,797 --> 00:56:06,732 INTERNAL WORKFORCE HERE AT 1347 00:56:06,732 --> 00:56:09,035 NIDCR, WE HAVE TO BE 1348 00:56:09,035 --> 00:56:10,236 INTROSPECTIVE AND MISSION 1349 00:56:10,236 --> 00:56:14,307 FOCUSED AND DO THIS WORK AT THE 1350 00:56:14,307 --> 00:56:16,275 INSTITUTE LEVEL THROUGH THE LENS 1351 00:56:16,275 --> 00:56:16,943 OF EQUITY. 1352 00:56:16,943 --> 00:56:21,113 AND THIS IS IN FULFILLMENT OF A 1353 00:56:21,113 --> 00:56:25,351 2021 EXECUTIVE ORDER ON DEIA IN 1354 00:56:25,351 --> 00:56:26,118 THE FEDERAL WORKFORCE, ALSO 1355 00:56:26,118 --> 00:56:27,687 CRITICAL FOR US TO MOVE THINGS 1356 00:56:27,687 --> 00:56:29,622 FORWARD IN THIS SPACE. 1357 00:56:29,622 --> 00:56:32,124 IN TERMS OF EXTERNAL WORKFORCE, 1358 00:56:32,124 --> 00:56:34,860 IT'S CRITICAL THAT WE SHARE AND 1359 00:56:34,860 --> 00:56:36,195 INVITE OTHERS INTO OUR COMMUNITY 1360 00:56:36,195 --> 00:56:38,030 BRINGING IN PEOPLE FROM OTHER 1361 00:56:38,030 --> 00:56:41,434 FIELDS, ALLOWING DIVERSITY OF 1362 00:56:41,434 --> 00:56:42,435 THOUGHT AND THEN ENSURING RACIAL 1363 00:56:42,435 --> 00:56:44,403 AND ETHNIC DIVERSITY, SO THAT WE 1364 00:56:44,403 --> 00:56:48,240 REFLECT THE DEMOGRAPHIC OF OUR 1365 00:56:48,240 --> 00:56:49,842 NATIONS THROUGH PATHWAY 1366 00:56:49,842 --> 00:56:50,109 BUILDING. 1367 00:56:50,109 --> 00:56:52,712 AND IN TERMS OF THE DISPARITIES 1368 00:56:52,712 --> 00:56:55,448 THEMSELVES WE NEED TO ENSURE THE 1369 00:56:55,448 --> 00:56:57,083 WAY WE'LL PROVIDE TOOLS TO 1370 00:56:57,083 --> 00:56:58,718 ENSURE STUDIES ARE INCLUSIVE AND 1371 00:56:58,718 --> 00:57:00,886 TO OPTIMIZE THE POTENTIAL FOR 1372 00:57:00,886 --> 00:57:03,522 TRANSLATION AND TO BUILD THE 1373 00:57:03,522 --> 00:57:04,624 EVIDENCE BASE THROUGH SCIENCE 1374 00:57:04,624 --> 00:57:07,526 THAT CANNOT ONLY SHIFT POLICIES 1375 00:57:07,526 --> 00:57:10,096 AND GUIDELINES THAT WILL HELP US 1376 00:57:10,096 --> 00:57:12,632 TO MOVE TOWARDS GETTING RID OF 1377 00:57:12,632 --> 00:57:13,933 THESE DISPARITIES, AND IT'S 1378 00:57:13,933 --> 00:57:17,770 GOING TO TAKE BUILDING AWARENESS 1379 00:57:17,770 --> 00:57:19,405 AND PARTNERSHIPS THAT FACILITATE 1380 00:57:19,405 --> 00:57:21,140 HEALTH APPROACHES THAT INCLUDE 1381 00:57:21,140 --> 00:57:23,042 ORAL HEALTH. 1382 00:57:23,042 --> 00:57:25,945 WE HAVE TO ADDRESS ALL THE 1383 00:57:25,945 --> 00:57:30,149 ISMs, AND WE KNOW THAT RACISM 1384 00:57:30,149 --> 00:57:32,351 AND OTHER ISMs, AGEISM, 1385 00:57:32,351 --> 00:57:34,620 SEXISM, ET CETERA, ARE OFTEN 1386 00:57:34,620 --> 00:57:36,055 SYSTEMIC AND STRUCTURAL. 1387 00:57:36,055 --> 00:57:38,124 WE KNOW IN ORDER TO IMPROVE 1388 00:57:38,124 --> 00:57:42,194 HUMAN HEALTH AND REDUCE THE 1389 00:57:42,194 --> 00:57:46,699 BURDEN OF DISEASE WE HAVE 1390 00:57:46,699 --> 00:57:48,100 ACHIEVED SCIENTIFIC WORK FORCE 1391 00:57:48,100 --> 00:57:51,170 DIVERSITY, AWARE IT CAN BE 1392 00:57:51,170 --> 00:57:51,971 HINDERED BY ORGANIZATIONAL 1393 00:57:51,971 --> 00:57:54,674 STRUCTURES AND SYSTEMS. 1394 00:57:54,674 --> 00:57:57,176 WE ALSO KNOW STRUCTURAL -- 1395 00:57:57,176 --> 00:57:59,178 STRUCTURES HAVE RESULTED IN 1396 00:57:59,178 --> 00:58:00,813 PERSISTENT HEALTH DISPARITIES 1397 00:58:00,813 --> 00:58:01,714 AND POOR HEALTH STATUS. 1398 00:58:01,714 --> 00:58:05,317 SO WHAT CAN WE DO TO CHANGE 1399 00:58:05,317 --> 00:58:05,985 THAT? 1400 00:58:05,985 --> 00:58:10,222 SO, WHAT WE'RE DOING HERE IS 1401 00:58:10,222 --> 00:58:13,392 APPLYING AN EQUITY LENS, WE CALL 1402 00:58:13,392 --> 00:58:17,930 THE REAL FRAMEWORK, ELEMENTS 1403 00:58:17,930 --> 00:58:22,501 INCLUDE AWARENESS IN 1404 00:58:22,501 --> 00:58:23,269 UNDERSTANDING, HABITS AND 1405 00:58:23,269 --> 00:58:24,370 STRUCTURES, INFLUENCE STRATEGY, 1406 00:58:24,370 --> 00:58:25,471 FEED BANK AND METRICS, 1407 00:58:25,471 --> 00:58:27,873 TRANSPARENCY AND TRUST. 1408 00:58:27,873 --> 00:58:31,177 ON THE RIGHT YOU SEE STRUCTURES 1409 00:58:31,177 --> 00:58:35,314 AND STRATEGIES IN PLACE AT 1410 00:58:35,314 --> 00:58:36,182 NIDCR. 1411 00:58:36,182 --> 00:58:41,020 I'M GOING TO NOW INTRODUCE JOY 1412 00:58:41,020 --> 00:58:42,655 COSTELL, OUR CHIEF DIVERSITY 1413 00:58:42,655 --> 00:58:45,391 OFFICER, WHO SERVES AS 1414 00:58:45,391 --> 00:58:46,258 INSTITUTIONAL CULTURAL CLIMATE 1415 00:58:46,258 --> 00:58:48,694 OFFICER, AND SHE WOULD BE HAPPY 1416 00:58:48,694 --> 00:58:50,096 TO INTERFACE WITH YOU TO SEE 1417 00:58:50,096 --> 00:58:51,397 ABOUT GETTING THESE TYPES OF 1418 00:58:51,397 --> 00:58:56,335 THINGS IN PLACE AT YOUR 1419 00:58:56,335 --> 00:58:56,769 INSTITUTION. 1420 00:58:56,769 --> 00:58:57,770 WE'RE TAKING AN INCLUSIVE 1421 00:58:57,770 --> 00:59:00,606 APPROACH WITH A BUILDING 1422 00:59:00,606 --> 00:59:01,807 BELONGING COLLABORATIVE, THROUGH 1423 00:59:01,807 --> 00:59:06,212 THIS COLLABORATIVE THESE ARE 1424 00:59:06,212 --> 00:59:08,247 VOLUNTEERS WHO ARE NIDCR 1425 00:59:08,247 --> 00:59:09,148 EMPLOYEES THAT VOLUNTEERED TO BE 1426 00:59:09,148 --> 00:59:12,551 INVOLVED IN WORKING GROUPS THAT 1427 00:59:12,551 --> 00:59:14,286 INCLUDE POLICIES, PRACTICES, 1428 00:59:14,286 --> 00:59:15,387 PROCEDURES. 1429 00:59:15,387 --> 00:59:16,255 ACCESSIBILITY AND STORY TELLING. 1430 00:59:16,255 --> 00:59:19,558 THE GOALS ARE NOT ONLY TO CHANGE 1431 00:59:19,558 --> 00:59:21,861 HABITS AND STRUCTURES, TO 1432 00:59:21,861 --> 00:59:23,829 IMPROVE TRANSPARENCY OF TRUST, 1433 00:59:23,829 --> 00:59:25,331 ALSO PROVIDE AWARENESS AND 1434 00:59:25,331 --> 00:59:26,232 UNDERSTANDING. 1435 00:59:26,232 --> 00:59:29,835 OUR FOCUS THIS YEAR IS 1436 00:59:29,835 --> 00:59:32,138 ACCOUNTABILITY, ACCESSIBILITY, 1437 00:59:32,138 --> 00:59:32,571 AWARENESS. 1438 00:59:32,571 --> 00:59:35,207 WITH GOALS TOWARD INCLUSION AND 1439 00:59:35,207 --> 00:59:35,808 PSYCHOLOGICAL SAFETY. 1440 00:59:35,808 --> 00:59:40,880 AND THIS IS JUST A LIST OF 1441 00:59:40,880 --> 00:59:41,814 INSTITUTIONAL/STRUCTURAL LEVEL 1442 00:59:41,814 --> 00:59:43,282 CHANGES THAT ARE BEING MADE OR 1443 00:59:43,282 --> 00:59:46,786 HAVE BEEN MADE HERE AT NIDCR 1444 00:59:46,786 --> 00:59:49,755 THAT ARE ASSOCIATED WITH 1445 00:59:49,755 --> 00:59:51,957 DIVERSITY, EQUITY, INCLUSION, 1446 00:59:51,957 --> 00:59:55,327 ACCESSIBILITY, AND BELONGING. 1447 00:59:55,327 --> 01:00:00,499 SO, WHAT ABOUT THE EXTERNAL 1448 01:00:00,499 --> 01:00:01,233 WORKFORCE? 1449 01:00:01,233 --> 01:00:01,467 OKAY. 1450 01:00:01,467 --> 01:00:02,501 TOWARD PATHWAY DEVELOPMENT I'M 1451 01:00:02,501 --> 01:00:05,204 GOING TO SHARE WITH YOU A LITTLE 1452 01:00:05,204 --> 01:00:07,673 BIT OF INFORMATION BUT MORE ON 1453 01:00:07,673 --> 01:00:08,974 SEVERAL OF THESE. 1454 01:00:08,974 --> 01:00:12,611 THERE'S NOW AN ORAL HEALTH 1455 01:00:12,611 --> 01:00:14,346 PATHWAY TASK FORCE. 1456 01:00:14,346 --> 01:00:15,748 WE'VE DEVELOPED GLOBALLY 1457 01:00:15,748 --> 01:00:16,916 AVAILABLE OUTREACH RESOURCES 1458 01:00:16,916 --> 01:00:19,919 THAT I'LL SHARE WITH YOU THAT 1459 01:00:19,919 --> 01:00:21,987 YOU CAN UTILIZE TO HELP PEOPLE 1460 01:00:21,987 --> 01:00:23,556 KNOW THAT DENTAL RESEARCH IS A 1461 01:00:23,556 --> 01:00:25,825 GREAT CAREER AND OPPORTUNITY FOR 1462 01:00:25,825 --> 01:00:26,158 THEM. 1463 01:00:26,158 --> 01:00:28,994 WE'RE WORKING TOWARD OUTREACH 1464 01:00:28,994 --> 01:00:31,764 AND ENGAGEMENT OF TRAINEES FROM 1465 01:00:31,764 --> 01:00:32,498 NIDCR-FUNDED NON-DENTAL 1466 01:00:32,498 --> 01:00:34,066 LABORATORIES AND ENVIRONMENTS TO 1467 01:00:34,066 --> 01:00:35,701 HELP BUILD THAT PATHWAY. 1468 01:00:35,701 --> 01:00:39,438 AND THEN OF COURSE OUR TRAINING 1469 01:00:39,438 --> 01:00:42,408 PROGRAMS AND MECHANISMS BOTH 1470 01:00:42,408 --> 01:00:45,010 INTRAMURAL AND EXTRAMURAL, ARE 1471 01:00:45,010 --> 01:00:47,913 SIGNIFICANTLY TARGETED TO 1472 01:00:47,913 --> 01:00:49,415 INCLUSION AND DIVERSITY. 1473 01:00:49,415 --> 01:00:52,251 AGAIN, THEY COULD BE OUTREACH -- 1474 01:00:52,251 --> 01:00:54,453 THERE WILL BE OUTREACH ACROSS 1475 01:00:54,453 --> 01:00:57,056 ACADEMIC INSTITUTIONS BY OUR 1476 01:00:57,056 --> 01:00:57,990 INSTITUTIONAL CLIMATE OFFICER. 1477 01:00:57,990 --> 01:01:01,794 AND WE WILL NEED TO LEVERAGE 1478 01:01:01,794 --> 01:01:02,795 PUBLIC/PRIVATE PARTNERSHIPS TO 1479 01:01:02,795 --> 01:01:04,430 HELP EXPAND OUR WORKFORCE. 1480 01:01:04,430 --> 01:01:06,298 JUST A LITTLE BIT ON 1481 01:01:06,298 --> 01:01:08,267 REENVISIONING THE ORAL HEALTH 1482 01:01:08,267 --> 01:01:10,436 RESEARCH WORKFORCE PATHWAY, I 1483 01:01:10,436 --> 01:01:12,504 THINK WE -- RENA SHARED LAST 1484 01:01:12,504 --> 01:01:14,473 COUNCIL THAT THERE WAS A MEETING 1485 01:01:14,473 --> 01:01:18,777 ACROSS A NUMBER OF STAKEHOLDERS, 1486 01:01:18,777 --> 01:01:21,847 PARTNERING, COLLABORATING TO 1487 01:01:21,847 --> 01:01:23,215 BUILD PROGRAMS, AND THE 1488 01:01:23,215 --> 01:01:25,451 CHALLENGES WERE DISCUSSED ACROSS 1489 01:01:25,451 --> 01:01:31,156 THE LIFE COURSE OF THE DENTISTS 1490 01:01:31,156 --> 01:01:33,859 AND DENTAL SCIENTISTS, AND YET 1491 01:01:33,859 --> 01:01:35,861 THOSE SCIENTISTS WORKING IN THE 1492 01:01:35,861 --> 01:01:37,863 DENTAL RESEARCH FIELD, AND IT 1493 01:01:37,863 --> 01:01:40,266 WAS DECIDED TO FOCUS ON THE K-12 1494 01:01:40,266 --> 01:01:42,635 GROUP, SO THAT GROUP HAS BEEN 1495 01:01:42,635 --> 01:01:48,574 NOW MEETING ON A REGULAR BASIS 1496 01:01:48,574 --> 01:01:50,976 TO DEVELOP PROGRAMMING IN A 1497 01:01:50,976 --> 01:01:52,711 COLLABORATIVE WAY THAT WILL HELP 1498 01:01:52,711 --> 01:01:54,246 BUILD NATIONAL PROGRAMS TO HELP 1499 01:01:54,246 --> 01:01:57,683 MOVE THINGS FORWARD IN THE K-12 1500 01:01:57,683 --> 01:01:57,883 SPACE. 1501 01:01:57,883 --> 01:01:59,985 SO WE'RE EXCITED TO SEE THAT 1502 01:01:59,985 --> 01:02:03,722 MOVE FORWARD. 1503 01:02:03,722 --> 01:02:05,457 WE HAVE DEVELOPED OUTREACH 1504 01:02:05,457 --> 01:02:07,526 RESOURCES THAT WILL BE AVAILABLE 1505 01:02:07,526 --> 01:02:10,596 GLOBALLY WITHIN THE NEXT TWO 1506 01:02:10,596 --> 01:02:13,098 WEEKS. 1507 01:02:13,098 --> 01:02:14,733 AND THIS RESOURCE, THE WEB PAGE 1508 01:02:14,733 --> 01:02:18,470 IS DOWN HERE, HIGHLIGHTS DENTAL 1509 01:02:18,470 --> 01:02:19,004 RESEARCHERS ACROSS FIELDS. 1510 01:02:19,004 --> 01:02:20,339 THERE ARE ARTICLES AVAILABLE. 1511 01:02:20,339 --> 01:02:22,741 THERE ARE LESSON PLANS FOR 1512 01:02:22,741 --> 01:02:24,944 TEACHERS, THERE ARE ANIMATIONS, 1513 01:02:24,944 --> 01:02:26,712 THERE'S A PODCAST, AND THIS IS 1514 01:02:26,712 --> 01:02:28,314 AVAILABLE TO GLOBAL AUDIENCE. 1515 01:02:28,314 --> 01:02:33,786 HERE'S AN EXAMPLE OF ONE OF THE 1516 01:02:33,786 --> 01:02:33,986 PAGES. 1517 01:02:33,986 --> 01:02:39,725 WE'VE HIGHLIGHTED BASIC 1518 01:02:39,725 --> 01:02:41,026 SCIENTISTS, TRANSLATIONAL 1519 01:02:41,026 --> 01:02:41,860 SCIENTISTS, CLINICIAN 1520 01:02:41,860 --> 01:02:45,397 RESEARCHERS, ACROSS MANY FIELDS. 1521 01:02:45,397 --> 01:02:48,934 ENDO, PEDIATRICS, ORAL MEDICINE, 1522 01:02:48,934 --> 01:02:50,102 AND OTHERS. 1523 01:02:50,102 --> 01:02:50,769 EPIDEMIOLOGY. 1524 01:02:50,769 --> 01:02:54,239 SO IT'S QUITE BROAD. 1525 01:02:54,239 --> 01:02:59,078 AND IN TERMS OF HOW UTILIZED 1526 01:02:59,078 --> 01:03:05,117 THESE ARE, THESE IS A SNAPSHOT 1527 01:03:05,117 --> 01:03:07,186 OF DECEMBER 2023, ALMOST 12,000 1528 01:03:07,186 --> 01:03:08,954 SITE VISITS, A THOUSAND 1529 01:03:08,954 --> 01:03:11,757 DOWNLOADS, YOU CAN SEE ACROSS 1530 01:03:11,757 --> 01:03:15,561 PLATFORMS LIKE FACEBOOK AND 1531 01:03:15,561 --> 01:03:17,596 PINTEREST AND OTHERS, LINKED IN, 1532 01:03:17,596 --> 01:03:18,697 ENGAGEMENTS AND IMPRESSIONS. 1533 01:03:18,697 --> 01:03:20,065 THIS IS A GREAT POTENTIAL 1534 01:03:20,065 --> 01:03:23,268 RESOURCE FOR US AS A COMMUNITY 1535 01:03:23,268 --> 01:03:23,569 TO UTILIZE. 1536 01:03:23,569 --> 01:03:25,904 AND AS SOON AS THIS IS AVAILABLE 1537 01:03:25,904 --> 01:03:28,240 PLEASE FEEL FREE TO DOWNLOAD IT 1538 01:03:28,240 --> 01:03:31,410 AND UTILIZE IN YOUR OWN 1539 01:03:31,410 --> 01:03:33,379 RECRUITMENT EFFORTS AS WE TARGET 1540 01:03:33,379 --> 01:03:35,114 INDIVIDUALS TO LET THEM KNOW, 1541 01:03:35,114 --> 01:03:37,216 ONE, WE NEED THEM TO HELP US 1542 01:03:37,216 --> 01:03:39,151 MOVE THE NEEDLE, AND, TWO, THIS 1543 01:03:39,151 --> 01:03:46,725 IS A GREAT CAREER OPPORTUNITY. 1544 01:03:46,725 --> 01:03:48,394 WHAT ELSE? 1545 01:03:48,394 --> 01:03:53,165 WE HAVE TRAINING, PROGRAM, CADRE 1546 01:03:53,165 --> 01:03:54,833 OF SCIENTIST, INTRAMURALLY LED 1547 01:03:54,833 --> 01:03:57,603 BY BELINDA HOUSER AND 1548 01:03:57,603 --> 01:04:03,175 EXTRAMURALLY EFFORTS LED BY 1549 01:04:03,175 --> 01:04:04,276 ANISSA BROWN. 1550 01:04:04,276 --> 01:04:07,012 PLEASE VISIT THE WEBSITE. 1551 01:04:07,012 --> 01:04:09,848 ALSO KNOW THAT NEXT WEDNESDAY, 1552 01:04:09,848 --> 01:04:12,718 JANUARY 31, THERE WILL BE A 1553 01:04:12,718 --> 01:04:15,454 WEBINAR FOCUSED ON INTRAMURAL 1554 01:04:15,454 --> 01:04:15,888 TRAINING AND CAREER 1555 01:04:15,888 --> 01:04:17,623 OPPORTUNITIES, SO PLEASE JOIN 1556 01:04:17,623 --> 01:04:22,594 AND LET PEOPLE KNOW IF THEY ARE 1557 01:04:22,594 --> 01:04:24,897 INTERESTED IN THESE 1558 01:04:24,897 --> 01:04:25,731 OPPORTUNITIES. 1559 01:04:25,731 --> 01:04:26,398 FINALLY, ORAL HEALTH 1560 01:04:26,398 --> 01:04:27,733 DISPARITIES, WHAT DO WE NEED TO 1561 01:04:27,733 --> 01:04:28,467 DO? 1562 01:04:28,467 --> 01:04:30,769 WE NEED TO PROVIDE TOOLS, WE 1563 01:04:30,769 --> 01:04:33,539 NEED TO ENSURE STUDIES ARE 1564 01:04:33,539 --> 01:04:35,707 INCLUSIVE AND, AGAIN, OPTIMIZE 1565 01:04:35,707 --> 01:04:40,846 POTENTIAL FOR TRANSLATION. 1566 01:04:40,846 --> 01:04:44,049 BUILDING EVIDENCE BASE, BUILDING 1567 01:04:44,049 --> 01:04:44,516 AWARENESS, LEVERAGING 1568 01:04:44,516 --> 01:04:44,850 PARTNERSHIPS. 1569 01:04:44,850 --> 01:04:46,685 A LITTLE BIT MORE AROUND THAT, 1570 01:04:46,685 --> 01:04:51,156 IN TERMS OF TOOLS TO IMPROVE AND 1571 01:04:51,156 --> 01:04:52,491 ASSESS TRANSLATION, WITHIN THE 1572 01:04:52,491 --> 01:04:56,995 NEXT MONTH OR SO THERE WILL BE 1573 01:04:56,995 --> 01:04:57,863 CLINICAL TRAINING MODULES 1574 01:04:57,863 --> 01:05:00,699 RELEASED, AND POSTED ON OUR 1575 01:05:00,699 --> 01:05:02,734 WEBSITE, AVAILABLE TO THE 1576 01:05:02,734 --> 01:05:04,436 COMMUNITY AROUND HOW TO DO 1577 01:05:04,436 --> 01:05:05,938 CLINICAL RESEARCH THAT CAN SERVE 1578 01:05:05,938 --> 01:05:10,342 AS BASIS OF A CURRICULUM OR FOR 1579 01:05:10,342 --> 01:05:12,211 SOMEONE WHO IS SHIFTING RESEARCH 1580 01:05:12,211 --> 01:05:13,846 IN A DIFFERENT DIRECTION TO 1581 01:05:13,846 --> 01:05:15,714 BEGIN TO DO CLINICAL RESEARCH, 1582 01:05:15,714 --> 01:05:19,651 FOR PEOPLE WHO HAVE MADE 1583 01:05:19,651 --> 01:05:20,953 DISCOVERIES AT THE BENCH, AND 1584 01:05:20,953 --> 01:05:24,256 WANT TO MOVE THIS TOWARDS 1585 01:05:24,256 --> 01:05:25,090 COMMERCIALIZATION, UNDERSTANDING 1586 01:05:25,090 --> 01:05:27,426 WHAT TO DO WILL COME IN THE 1587 01:05:27,426 --> 01:05:30,362 CONTEXT OF A PRE-CLINICAL MODULE 1588 01:05:30,362 --> 01:05:33,899 THAT WILL BE AVAILABLE OR 1589 01:05:33,899 --> 01:05:34,933 RELEASED MIDDLE OF YEAR. 1590 01:05:34,933 --> 01:05:39,638 HOW DO YOU INTERFACE WITH FDA 1591 01:05:39,638 --> 01:05:43,175 AND DO AN IND, AND MANY OTHER 1592 01:05:43,175 --> 01:05:45,978 DIFFERENT TENETS CRITICAL FOR 1593 01:05:45,978 --> 01:05:51,350 MOVING FROM DISCOVERY AND MOVING 1594 01:05:51,350 --> 01:05:52,017 INNOVATIONS TOWARDS 1595 01:05:52,017 --> 01:05:52,784 THERAPEUTICS. 1596 01:05:52,784 --> 01:05:55,521 TO ASSESS OUR IMPACT ACROSS THE 1597 01:05:55,521 --> 01:05:58,857 FIELD, NIDCR AND DAVID BRADLEY 1598 01:05:58,857 --> 01:06:00,826 HAVE SPEARHEADED BUILDING OF A 1599 01:06:00,826 --> 01:06:05,497 TRANSLATION BROWSER THAT ALLOWS 1600 01:06:05,497 --> 01:06:09,201 US TO LOOK AT NIDCR FUNDING AND 1601 01:06:09,201 --> 01:06:09,801 INVESTMENTS, PUBLICATIONS THAT 1602 01:06:09,801 --> 01:06:12,504 COME OUT AS A RESULT OF THOSE 1603 01:06:12,504 --> 01:06:15,807 THINGS, LINKS TO PATENTS, 1604 01:06:15,807 --> 01:06:18,744 THROUGH PHARMA, FDA APPROVALS, 1605 01:06:18,744 --> 01:06:19,211 AND DRUGS. 1606 01:06:19,211 --> 01:06:23,916 AND SO THIS IS THE THING THAT 1607 01:06:23,916 --> 01:06:25,217 IS -- HAS BEEN DEVELOPED, AND WE 1608 01:06:25,217 --> 01:06:28,520 HOPE TO BE ABLE TO SHARE THE 1609 01:06:28,520 --> 01:06:30,722 RESULTS OF THESE MANY 1610 01:06:30,722 --> 01:06:32,591 INNOVATIONS THAT NIDCR HAS 1611 01:06:32,591 --> 01:06:34,126 SPEARHEADED THAT ARE REALLY 1612 01:06:34,126 --> 01:06:36,628 HELPING ACROSS MULTIPLE FIELDS 1613 01:06:36,628 --> 01:06:37,729 OF HEALTH AND MEDICINE. 1614 01:06:37,729 --> 01:06:45,737 I JUST WANT TO SHARE THAT ANNA 1615 01:06:45,737 --> 01:06:47,372 NICHOLSON'S GROUP, ORLANDO LOPEZ 1616 01:06:47,372 --> 01:06:50,008 AND DAVID BRADLEY HAVE BEEN 1617 01:06:50,008 --> 01:06:52,844 CENTRAL TO DEVELOPING THESE 1618 01:06:52,844 --> 01:06:53,312 MODULES. 1619 01:06:53,312 --> 01:06:56,248 THE OTHER IMPORTANT THING IS 1620 01:06:56,248 --> 01:07:00,752 TO -- IN TERMS OF EXCLUSIVITY TO 1621 01:07:00,752 --> 01:07:02,821 UTILIZE SKILLS OF CHIEF 1622 01:07:02,821 --> 01:07:05,657 DIVERSITY OFFICER, AS WE'RE 1623 01:07:05,657 --> 01:07:10,729 DOING HERE, TO PROVIDE INPUT ON 1624 01:07:10,729 --> 01:07:11,797 CLINICAL TRIALS AND INCLUSION. 1625 01:07:11,797 --> 01:07:14,299 NOW AS WE LOOK AT ACTUALIZING 1626 01:07:14,299 --> 01:07:18,003 THIS, WE CAN LOOK ACROSS OUR 1627 01:07:18,003 --> 01:07:19,338 STRATEGIC PRIORITIES, 1628 01:07:19,338 --> 01:07:20,205 INTEGRATING ORAL AND GENERAL 1629 01:07:20,205 --> 01:07:21,840 HEALTH, HERE IN TERMS OF 1630 01:07:21,840 --> 01:07:24,276 DISPARITIES WE HAVE TO FOCUS AND 1631 01:07:24,276 --> 01:07:26,144 LEVERAGE WHOLE PERSON HEALTH 1632 01:07:26,144 --> 01:07:28,880 EFFORTS IN ORDER TO UNDERSTAND 1633 01:07:28,880 --> 01:07:34,987 IMPACT AND OPTIMIZE PREVENTION. 1634 01:07:34,987 --> 01:07:37,489 STRATEGIC PRIORITY TWO PRECISION 1635 01:07:37,489 --> 01:07:39,124 DENTAL MEDICINE, UTILIZING 1636 01:07:39,124 --> 01:07:39,791 BIOLOGIC AND SOCIAL DETERMINANTS 1637 01:07:39,791 --> 01:07:42,861 OF HEALTH DATA DOWN THE ROAD TO 1638 01:07:42,861 --> 01:07:44,830 UNDERSTAND SPECIFIC NEEDS WITHIN 1639 01:07:44,830 --> 01:07:45,264 COMMUNITIES. 1640 01:07:45,264 --> 01:07:49,635 AND WE CAN WORK TOWARDS 1641 01:07:49,635 --> 01:07:55,207 TARGETING NIDCR TECHNOLOGIES TO 1642 01:07:55,207 --> 01:07:57,609 UNDERSERVED MARKETS. 1643 01:07:57,609 --> 01:07:59,378 TRANSLATE AND IMPLEMENT, 3, 1644 01:07:59,378 --> 01:08:02,347 TRANSLATE DISCOVERIES TO WIDEST 1645 01:08:02,347 --> 01:08:03,081 POSSIBLE POPULATION DEMOGRAPHIC 1646 01:08:03,081 --> 01:08:04,616 ACROSS THE NATION AND THIS 1647 01:08:04,616 --> 01:08:06,918 RESONATES WITH WHAT YOU'VE HEARD 1648 01:08:06,918 --> 01:08:08,687 FROM DR. D'SOUZA JUST A FEW 1649 01:08:08,687 --> 01:08:09,254 MINUTES EARLIER. 1650 01:08:09,254 --> 01:08:12,391 WE NEED TO PROVIDE THESE TOOLS 1651 01:08:12,391 --> 01:08:14,593 TO FACILITATE THIS. 1652 01:08:14,593 --> 01:08:17,763 AND FINALLY, WHEN WE WORK 1653 01:08:17,763 --> 01:08:19,197 TOWARDS IMPLEMENTATION WE MUST 1654 01:08:19,197 --> 01:08:21,533 CONSIDER DIVERSITY, NOT ONLY IN 1655 01:08:21,533 --> 01:08:24,936 OUR TRIALS BUT ALSO IN THE 1656 01:08:24,936 --> 01:08:28,073 SCIENCE THAT WE DO AT THE EDGE. 1657 01:08:28,073 --> 01:08:29,708 WE TALK ABOUT DIVERSE PIPELINE, 1658 01:08:29,708 --> 01:08:34,012 HOW THAT CAN AID IN DEPLOYING 1659 01:08:34,012 --> 01:08:37,716 SCIENTIFIC EFFORTS AROUND 1660 01:08:37,716 --> 01:08:38,250 DISPARITIES. 1661 01:08:38,250 --> 01:08:43,055 BUT CRITICAL IS STRATEGIC 1662 01:08:43,055 --> 01:08:44,923 PRIORITY 5, THAT'S PARTNER AND 1663 01:08:44,923 --> 01:08:45,624 COLLABORATION. 1664 01:08:45,624 --> 01:08:47,359 I'LL SHARE PARTNERSHIPS AND 1665 01:08:47,359 --> 01:08:49,394 COLLABORATIONS CURRENTLY IN 1666 01:08:49,394 --> 01:08:50,162 PLACE. 1667 01:08:50,162 --> 01:08:52,564 SO, AGAIN, WE MUST BUILD 1668 01:08:52,564 --> 01:08:53,231 AWARENESS, LEVERAGE 1669 01:08:53,231 --> 01:08:55,767 PARTNERSHIPS, AND THEN BUILD THE 1670 01:08:55,767 --> 01:09:01,206 EVIDENCE BASE RELATED TO 1671 01:09:01,206 --> 01:09:02,040 DISPARITIES AND PREVENTION. 1672 01:09:02,040 --> 01:09:04,843 IN THE AREA OF DATA SCIENCE AND 1673 01:09:04,843 --> 01:09:06,878 STUDIES ACROSS AGENCY AND ACROSS 1674 01:09:06,878 --> 01:09:08,647 THE I.C., I WANT TO LET YOU KNOW 1675 01:09:08,647 --> 01:09:12,718 THE OFFICE OF DISEASE PREVENTION 1676 01:09:12,718 --> 01:09:17,189 IN 2022 MOVED HEALTH DISPARITIES 1677 01:09:17,189 --> 01:09:19,658 FROM A CROSS CUTTING THEME TO 1678 01:09:19,658 --> 01:09:20,692 STRATEGIC PRIORITY. 1679 01:09:20,692 --> 01:09:22,761 SO THERE'S AWARENESS OF 1680 01:09:22,761 --> 01:09:25,163 IMPORTANCE OF HEALTH DISPARITIES 1681 01:09:25,163 --> 01:09:25,497 THERE. 1682 01:09:25,497 --> 01:09:27,532 THERE'S CONGRESSIONAL AWARENESS 1683 01:09:27,532 --> 01:09:30,635 OF MEDICALLY NECESSARY 1684 01:09:30,635 --> 01:09:31,503 DENTISTRY. 1685 01:09:31,503 --> 01:09:33,805 IN THE SENATE APPROPRIATIONS 1686 01:09:33,805 --> 01:09:37,542 BILL SPEARHEADED BY BEN CARDON, 1687 01:09:37,542 --> 01:09:40,379 DENTAL CARE IS LINKED CLOSELY TO 1688 01:09:40,379 --> 01:09:42,581 CLINICAL SUCCESS OF COVERED 1689 01:09:42,581 --> 01:09:44,249 MEDICAL SERVICES, THE 1690 01:09:44,249 --> 01:09:45,984 CONGRESSIONAL COMMITTEE URGES 1691 01:09:45,984 --> 01:09:48,019 NIH TO FUND ADDITIONAL RESEARCH 1692 01:09:48,019 --> 01:09:51,022 IN THIS AREA. 1693 01:09:51,022 --> 01:09:57,162 WE WILL BE PROMOTING AWARENESS 1694 01:09:57,162 --> 01:09:58,830 ACROSS COMMUNITIES, FOR EXAMPLE 1695 01:09:58,830 --> 01:10:04,870 NIDCR HAS PARTNERED WITH ADA FOR 1696 01:10:04,870 --> 01:10:15,547 FEBRUARY OF 2024, TWO WEBINARS, 1697 01:10:15,547 --> 01:10:18,750 ONE FOCUSED ON FLUORODATION AND 1698 01:10:18,750 --> 01:10:21,920 SEALANT IMPLEMENTATION, SCHOOL 1699 01:10:21,920 --> 01:10:23,321 NURSES, PEDIATRICIANS, FAMILY 1700 01:10:23,321 --> 01:10:23,989 MEDICINE AND OTHERS. 1701 01:10:23,989 --> 01:10:26,825 WE'VE PARTNERED WITH THE FDA A 1702 01:10:26,825 --> 01:10:28,427 MEETING TO DISCUSS REDUCTION OF 1703 01:10:28,427 --> 01:10:29,394 ADDED SUGARS. 1704 01:10:29,394 --> 01:10:30,896 OF COURSE OUR AREA WAS ORAL 1705 01:10:30,896 --> 01:10:33,498 HEALTH, IN NOVEMBER OF THIS 1706 01:10:33,498 --> 01:10:33,732 YEAR. 1707 01:10:33,732 --> 01:10:35,700 WE'RE PARTNERING WITH NIMHD AS 1708 01:10:35,700 --> 01:10:38,236 WE THINK ABOUT DATA AND ORAL 1709 01:10:38,236 --> 01:10:39,638 HEALTH DISPARITIES. 1710 01:10:39,638 --> 01:10:42,441 AND IN THE COLLABORATION WITH 1711 01:10:42,441 --> 01:10:44,609 NIMHD WE WILL BE UTILIZING THE 1712 01:10:44,609 --> 01:10:47,446 SCIENCE COLLABORATIVE FOR HEALTH 1713 01:10:47,446 --> 01:10:50,515 DISPARITIES AND ARTIFICIAL 1714 01:10:50,515 --> 01:10:52,517 INTELLIGENCE BIAS REDUCTION 1715 01:10:52,517 --> 01:10:55,720 SYSTEM WITHIN THE DDS ECOSYSTEM 1716 01:10:55,720 --> 01:10:57,522 THAT MAY NOT HAVE SHARED WITH 1717 01:10:57,522 --> 01:10:58,423 YOU EARLIER. 1718 01:10:58,423 --> 01:11:03,862 THIS WILL BE CENTRAL TO CARIES 1719 01:11:03,862 --> 01:11:07,365 EQUITY PROGRAM, SPEARHEADED BY 1720 01:11:07,365 --> 01:11:08,800 AKITA, A COMMUNITY-BASED 1721 01:11:08,800 --> 01:11:11,336 PARTICIPATORY APPROACH TO DESIGN 1722 01:11:11,336 --> 01:11:12,404 POPULATION-BASED STRATEGIES FOR 1723 01:11:12,404 --> 01:11:14,506 REDUCING CARIES, AND THIS WILL 1724 01:11:14,506 --> 01:11:17,375 ALSO BE VERY IMPORTANT TO THE 1725 01:11:17,375 --> 01:11:20,812 DDS PORTAL THAT WILL BE 1726 01:11:20,812 --> 01:11:21,179 DEVELOPED. 1727 01:11:21,179 --> 01:11:27,285 WE'RE PARTNERS ACROSS FEDERAL 1728 01:11:27,285 --> 01:11:29,154 AGENCIES, PROVIDING EVIDENCE TO 1729 01:11:29,154 --> 01:11:34,726 SUPPORT COVERAGE OF MEDICALLY 1730 01:11:34,726 --> 01:11:37,462 NECESSARY DENTISTRY, HAS MADE 1731 01:11:37,462 --> 01:11:38,763 SIGNIFICANT DIFFERENCE IN 1732 01:11:38,763 --> 01:11:40,632 SEVERAL AREAS WITH TRANSPLANT, 1733 01:11:40,632 --> 01:11:43,068 CANCER CHEMOTHERAPY, AS WELL AS 1734 01:11:43,068 --> 01:11:43,702 RADIATION. 1735 01:11:43,702 --> 01:11:46,371 NIDCR IS INVOLVED WITH HEALTHY 1736 01:11:46,371 --> 01:11:48,106 PEOPLE 2030, AND FOUR AREAS 1737 01:11:48,106 --> 01:11:49,975 FOCUSED ON ORAL HEALTH, IN FACT 1738 01:11:49,975 --> 01:11:52,611 DENTAL UTILIZATION IS A LEADING 1739 01:11:52,611 --> 01:11:53,812 HEALTH INDICATOR. 1740 01:11:53,812 --> 01:11:58,083 I TALKED ABOUT THE FDA AND NIDCR 1741 01:11:58,083 --> 01:12:01,253 AND THE CDC HAVE ONGOING 1742 01:12:01,253 --> 01:12:03,121 COLLABORATIVE STUDIES RELATED TO 1743 01:12:03,121 --> 01:12:03,989 NATIONAL ASSESSMENT OF ORAL 1744 01:12:03,989 --> 01:12:07,292 HEALTH IN THE CONTEXT OF CHRONIC 1745 01:12:07,292 --> 01:12:08,460 METABOLIC DISEASE. 1746 01:12:08,460 --> 01:12:12,531 WE HAVE ADDED TO THE TEAM SHARON 1747 01:12:12,531 --> 01:12:14,266 JACKSON, A DISPARITIES EXPERT, 1748 01:12:14,266 --> 01:12:15,500 AND BRINGS SIGNIFICANT 1749 01:12:15,500 --> 01:12:18,303 EXPERIENCE AFTER HER TIME AT 1750 01:12:18,303 --> 01:12:26,645 NIMHD INTRAMURAL. 1751 01:12:26,645 --> 01:12:29,481 WE'RE PARTNERS THROUGH THE ORAL 1752 01:12:29,481 --> 01:12:30,916 HEALTH COORDINATING COMMITTEE, 1753 01:12:30,916 --> 01:12:33,952 FEDERAL COMMITTEES THANE INCLUDE 1754 01:12:33,952 --> 01:12:36,187 ABOUT 16 AGENCIES TO MOVE NEEDLE 1755 01:12:36,187 --> 01:12:39,591 ON DISPARITIES AS WELL AS 1756 01:12:39,591 --> 01:12:40,792 MEDICAL/DENTAL INTEGRATION. 1757 01:12:40,792 --> 01:12:43,328 WE ARE INVOLVED WITH NATIONAL 1758 01:12:43,328 --> 01:12:48,900 ORAL HEALTH STRATEGIC FRAMEWORK 1759 01:12:48,900 --> 01:12:50,001 CURRENTLY UNDERREVIEW, FOR 1760 01:12:50,001 --> 01:12:51,970 2024-29, WORKING TO HELP SUPPORT 1761 01:12:51,970 --> 01:12:54,372 A NATIONAL ACADEMY OF MEDICINE 1762 01:12:54,372 --> 01:12:56,174 REPORT FOCUSED ON ACTION 1763 01:12:56,174 --> 01:12:59,411 ORIENTED ELIMINATION OF ORAL 1764 01:12:59,411 --> 01:13:01,513 HEALTH DISPARITIES, WITH PUBLIC 1765 01:13:01,513 --> 01:13:03,815 AND PRIVATE PARTNERS AND WORKING 1766 01:13:03,815 --> 01:13:06,017 WITH PUBLIC AND PRIVATE PARTNERS 1767 01:13:06,017 --> 01:13:08,086 TOWARD A NATIONAL STRATEGY THAT 1768 01:13:08,086 --> 01:13:10,388 COULD MODEL NUTRITION STRATEGY 1769 01:13:10,388 --> 01:13:16,962 AND FOCUS IN THESE AREAS AMONG 1770 01:13:16,962 --> 01:13:20,165 OTHERS, IMPROVING ACCESS AND 1771 01:13:20,165 --> 01:13:21,666 AFFORDABILITY, INTEGRATING ORAL 1772 01:13:21,666 --> 01:13:23,201 HEALTH, EMPOWERING ACCESS TO 1773 01:13:23,201 --> 01:13:25,604 HEALTH, ENHANCING ORAL HEALTH 1774 01:13:25,604 --> 01:13:27,472 RESEARCH AND INNOVATION. 1775 01:13:27,472 --> 01:13:28,873 THE U.S. PREVENTIVE TASK 1776 01:13:28,873 --> 01:13:33,612 SERVICES AS YOU MAY KNOW 1777 01:13:33,612 --> 01:13:34,846 PROVIDED AND SHARED INEFFICIENT 1778 01:13:34,846 --> 01:13:35,947 EVIDENCE FOR RECOMMENDATION OF 1779 01:13:35,947 --> 01:13:38,016 ORAL HEALTH SCREENING AND 1780 01:13:38,016 --> 01:13:40,218 PREVENTIVE INTERVENTIONS FOR 1781 01:13:40,218 --> 01:13:42,087 CHILDREN AND ADULTS IN PRIMARY 1782 01:13:42,087 --> 01:13:43,622 HEALTH CARE SETTINGS, IN 1783 01:13:43,622 --> 01:13:44,956 RESPONSE WE'RE CALLING FOR MORE 1784 01:13:44,956 --> 01:13:47,359 ORAL HEALTH RESEARCH IN PRIMARY 1785 01:13:47,359 --> 01:13:51,296 CARE, AND THERE WILL BE A NOSI 1786 01:13:51,296 --> 01:13:54,466 UPCOMING RELATED TO ORAL HEALTH 1787 01:13:54,466 --> 01:13:56,668 DISPARITIES, WITH FOCUS ON 1788 01:13:56,668 --> 01:13:59,070 CO-LOCATED SITES, MEDICAL AND 1789 01:13:59,070 --> 01:14:01,272 DENTAL, AND MULTIPLE ARENAS 1790 01:14:01,272 --> 01:14:04,542 INCLUDING INDIAN HEALTH SERVICE, 1791 01:14:04,542 --> 01:14:06,344 V.A., FEDERALLY QUALIFIED HEALTH 1792 01:14:06,344 --> 01:14:08,713 CARE CENTERS AND OTHERS. 1793 01:14:08,713 --> 01:14:10,882 WE'RE ALSO WORKING WITH OTHER 1794 01:14:10,882 --> 01:14:12,317 INSTITUTES TO HELP THEM VIEW 1795 01:14:12,317 --> 01:14:15,487 ORAL HEALTH AS A MODIFIABLE RISK 1796 01:14:15,487 --> 01:14:17,022 FACTOR, AND WORKING TOWARDS 1797 01:14:17,022 --> 01:14:18,990 ADDING QUESTIONS ABOUT ORAL 1798 01:14:18,990 --> 01:14:20,291 HEALTH TO EXISTING TRIAL 1799 01:14:20,291 --> 01:14:28,166 EFFORTS, CENTRAL TO ALL OF THIS 1800 01:14:28,166 --> 01:14:29,801 DISPARITIES WORK IS CENTER FOR 1801 01:14:29,801 --> 01:14:34,739 CLINICAL WORK IN ADDITION TO 1802 01:14:34,739 --> 01:14:38,009 SHARON JACKSON AND CDO 1803 01:14:38,009 --> 01:14:39,444 HIGHLIGHTED HERE. 1804 01:14:39,444 --> 01:14:40,979 OUR IMPERATIVE BECAUSE POOR ORAL 1805 01:14:40,979 --> 01:14:42,180 HEALTH AND HEALTH DISPARITIES 1806 01:14:42,180 --> 01:14:49,754 HAVE NOT ONLY HIGH INDIVIDUAL 1807 01:14:49,754 --> 01:14:52,657 BUT HIGH SOCIETAL COSTS. 1808 01:14:52,657 --> 01:14:56,461 I WILL GIVE IT BACK TO RENA. 1809 01:14:56,461 --> 01:14:59,898 >> WE'RE A LITTLE BIT AHEAD OF 1810 01:14:59,898 --> 01:15:04,169 TIME FOR DR. WOYCHIK SO WE 1811 01:15:04,169 --> 01:15:06,705 SHOULD TAKE A 10-MINUTE BREAK. 1812 01:15:06,705 --> 01:15:10,942 >> LYNN, I NEED TO BE ALLOWED IN 1813 01:15:10,942 --> 01:15:11,476 THE VIDEO. 1814 01:15:11,476 --> 01:15:20,485 WE COULD OPEN FOR QUESTIONS. 1815 01:15:20,485 --> 01:15:27,158 >> ABSOLUTELY. 1816 01:15:27,158 --> 01:15:29,127 >> PAUL'S QUESTION, THANK YOU. 1817 01:15:29,127 --> 01:15:32,197 >> THANK YOU, JENNIFER. 1818 01:15:32,197 --> 01:15:34,032 I THINK IT'S SO IMPORTANT WE 1819 01:15:34,032 --> 01:15:36,901 CONTINUE TO STUDY THE HEALTH 1820 01:15:36,901 --> 01:15:40,839 DISPARITIES AND ALTHOUGH WE HAVE 1821 01:15:40,839 --> 01:15:44,109 A LOT TO DO, IT'S CLEAR WITH THE 1822 01:15:44,109 --> 01:15:47,612 DATA WE ALREADY HAVE THAT 1823 01:15:47,612 --> 01:15:48,813 EQUITY, DIVERSITY, AND INCLUSION 1824 01:15:48,813 --> 01:15:51,783 IN SCIENCE AND CLINICAL STUDIES 1825 01:15:51,783 --> 01:15:53,618 AND CLINICAL TREATMENTS IS 1826 01:15:53,618 --> 01:15:56,254 VITALLY IMPORTANT. 1827 01:15:56,254 --> 01:16:01,960 I'M WONDERING, EXCUSE ME, IF NIH 1828 01:16:01,960 --> 01:16:02,761 OR THE SECRETARY OF HEALTH AND 1829 01:16:02,761 --> 01:16:06,664 HUMAN SERVICES IN A BIGGER 1830 01:16:06,664 --> 01:16:09,400 CATEGORY ARE WORRIED ABOUT THIS 1831 01:16:09,400 --> 01:16:12,137 ANTI-EDI BUZZ SAW THAT SEEMS TO 1832 01:16:12,137 --> 01:16:14,906 BE GOING ACROSS OUR COUNTRY. 1833 01:16:14,906 --> 01:16:18,510 IS THERE ANYTHING THAT NIH OR 1834 01:16:18,510 --> 01:16:21,312 HHS CAN DO WHILE THEY ARE 1835 01:16:21,312 --> 01:16:25,183 MEETING WITH CONGRESS AND -- 1836 01:16:25,183 --> 01:16:28,353 >> PAUL, THANK YOU FOR SHARING. 1837 01:16:28,353 --> 01:16:30,121 THE ANSWER IS ABSOLUTELY YES. 1838 01:16:30,121 --> 01:16:31,856 THE QUESTION IS HOW TO GET AHEAD 1839 01:16:31,856 --> 01:16:35,593 OF THE BUZZ SAW, RIGHT? 1840 01:16:35,593 --> 01:16:40,198 RECOGNIZING THAT THIS IS A BIG 1841 01:16:40,198 --> 01:16:43,134 PROBLEM FOR ALL AMERICANS IN 1842 01:16:43,134 --> 01:16:45,336 TERMS OF THIS EPIDEMIC OF ORAL 1843 01:16:45,336 --> 01:16:46,104 DISEASE. 1844 01:16:46,104 --> 01:16:50,675 PERHAPS IT'S HOW THIS IS FRAMED, 1845 01:16:50,675 --> 01:16:51,543 RIGHT? 1846 01:16:51,543 --> 01:16:53,978 NOT FRAMING IT NECESSARILY AS A 1847 01:16:53,978 --> 01:16:55,613 DIVERSITY CHALLENGE BUT A 1848 01:16:55,613 --> 01:17:01,419 CHALLENGE ACROSS ALL OF OUR 1849 01:17:01,419 --> 01:17:03,288 POPULATIONS AND CONSTITUENTS. 1850 01:17:03,288 --> 01:17:05,924 AN EXAMPLE INTERNALLY, OUR CDO 1851 01:17:05,924 --> 01:17:09,994 SERVES AS OUR INSTITUTIONAL 1852 01:17:09,994 --> 01:17:11,729 CULTURAL CLIMATE OFFICER, RIGHT? 1853 01:17:11,729 --> 01:17:13,998 IF THE BUZZ SAW SAYS WE CAN'T 1854 01:17:13,998 --> 01:17:14,799 MAINTAIN THIS DIVERSITY THING, 1855 01:17:14,799 --> 01:17:17,502 WE WOULD STILL BE IN GOOD SHAPE. 1856 01:17:17,502 --> 01:17:21,139 SO I THINK THE KEY IS STEPPING 1857 01:17:21,139 --> 01:17:22,106 BACK, THINKING ABOUT WHAT IT IS 1858 01:17:22,106 --> 01:17:24,742 AND WHO IT IS WE'RE TRYING TO 1859 01:17:24,742 --> 01:17:27,245 MAKE A DIFFERENCE FOR, AND FRAME 1860 01:17:27,245 --> 01:17:32,183 IT SUCH THAT THE BUZZ SAW WILL 1861 01:17:32,183 --> 01:17:36,554 BE BLUNTED. 1862 01:17:36,554 --> 01:17:39,724 BUT OASH AND NIH AT LARGE AND 1863 01:17:39,724 --> 01:17:40,592 NIDCR HAVE THOUGHT A GREAT DEAL 1864 01:17:40,592 --> 01:17:42,493 ABOUT THAT. 1865 01:17:42,493 --> 01:17:51,536 >> THANK YOU. 1866 01:17:51,536 --> 01:17:54,138 >> ANY OTHER QUESTIONS OR 1867 01:17:54,138 --> 01:18:04,315 COMMENTS? 1868 01:18:05,850 --> 01:18:10,088 PAUL'S HAND WOULD BE DOWN NOW. 1869 01:18:10,088 --> 01:18:10,555 >> I MEAN -- 1870 01:18:10,555 --> 01:18:12,023 >> I HAVE A NEW QUESTION IF 1871 01:18:12,023 --> 01:18:21,232 THERE'S NO ONE ELSE OUT THERE. 1872 01:18:21,232 --> 01:18:21,966 >> OKAY, PAUL. 1873 01:18:21,966 --> 01:18:25,937 >> A SLIDE RENA HAD UP EARLIER, 1874 01:18:25,937 --> 01:18:30,074 IN HER SECOND SEGMENT MAYBE, 1875 01:18:30,074 --> 01:18:31,476 TALKED ABOUT THE DATA-DRIVEN 1876 01:18:31,476 --> 01:18:32,911 PROJECTS I BELIEVE. 1877 01:18:32,911 --> 01:18:35,213 AND YOU HAD A LIST ON THE 1878 01:18:35,213 --> 01:18:39,150 LEFT-HAND SIDE OF THE SCREEN 1879 01:18:39,150 --> 01:18:40,685 ABOUT HOW MANY PROJECTS WERE 1880 01:18:40,685 --> 01:18:41,219 FUNDED. 1881 01:18:41,219 --> 01:18:46,291 IT SEEMED TO ME THERE WAS A HUGE 1882 01:18:46,291 --> 01:18:48,459 DISPROPORTIONAL LEVEL OF R03s 1883 01:18:48,459 --> 01:18:50,762 VERSUS R01s, WONDERING IS THAT 1884 01:18:50,762 --> 01:18:54,165 A POINT OF EMPHASIS FOR NIDCR OR 1885 01:18:54,165 --> 01:18:56,034 JUST IS THERE SOMETHING -- DOES 1886 01:18:56,034 --> 01:18:59,203 IT MEAN SOMETHING ELSE? 1887 01:18:59,203 --> 01:19:02,907 FIFTY-SOME R03s, AND LIKE NINE 1888 01:19:02,907 --> 01:19:03,107 R01s. 1889 01:19:03,107 --> 01:19:04,642 IS THAT A NEW GENERATION, YOUNG 1890 01:19:04,642 --> 01:19:06,644 INVESTIGATORS ARE MORE 1891 01:19:06,644 --> 01:19:07,578 INTERESTED IN THIS? 1892 01:19:07,578 --> 01:19:10,014 >> I'LL LET LILLIAN GIVE THE 1893 01:19:10,014 --> 01:19:10,214 FACTS. 1894 01:19:10,214 --> 01:19:13,284 I'M GUESSING WE PUT OUT THE 1895 01:19:13,284 --> 01:19:14,285 RFAs, EXPLORATORY KIND OF 1896 01:19:14,285 --> 01:19:16,254 OPPORTUNITIES, IN THE FIELD 1897 01:19:16,254 --> 01:19:19,958 THAT'S EMERGENT THAT YOU WOULD 1898 01:19:19,958 --> 01:19:24,128 GET THAT KIND OF DISPARATE AWARD 1899 01:19:24,128 --> 01:19:24,529 DATA. 1900 01:19:24,529 --> 01:19:26,864 BUT LILLIAN, PLEASE GIVE PAUL 1901 01:19:26,864 --> 01:19:28,967 THE RIGHT ANSWER. 1902 01:19:28,967 --> 01:19:30,868 >> OF COURSE. 1903 01:19:30,868 --> 01:19:32,904 THANKS FOR THAT QUESTION AND 1904 01:19:32,904 --> 01:19:33,237 OBSERVATION. 1905 01:19:33,237 --> 01:19:38,576 SO THE REASON IS BECAUSE WE HAVE 1906 01:19:38,576 --> 01:19:40,778 FUNDING OPPORTUNITIES TO INVITE 1907 01:19:40,778 --> 01:19:43,181 R03 APPLICATIONS TO FOCUS ON 1908 01:19:43,181 --> 01:19:46,351 SECONDARY DATA ANALYSIS OF 1909 01:19:46,351 --> 01:19:49,087 EXISTING DATASET NIDCR SUPPORTED 1910 01:19:49,087 --> 01:19:50,421 OR NATIONAL DATASET LIKE THE 1911 01:19:50,421 --> 01:19:52,690 "ALL OF US" PROGRAM. 1912 01:19:52,690 --> 01:19:55,093 AND PREVIOUSLY WE ALSO HAVE 1913 01:19:55,093 --> 01:19:56,728 SPECIFIC FUNDING OPPORTUNITIES 1914 01:19:56,728 --> 01:19:59,030 FOR PEOPLE TO ANALYZE 1915 01:19:59,030 --> 01:20:00,465 FAITH-BASED DATASET AND JOINT 1916 01:20:00,465 --> 01:20:02,967 FORCES WITH INSTITUTES. 1917 01:20:02,967 --> 01:20:08,006 THAT'S WHY WE HAVE AN AREA, ALSO 1918 01:20:08,006 --> 01:20:11,509 EMPHASIS BUT OPPORTUNITY AND 1919 01:20:11,509 --> 01:20:13,511 ENTRY POINT AND RESOURCES TO GET 1920 01:20:13,511 --> 01:20:16,214 INTO DATA SCIENCE BY STARTING 1921 01:20:16,214 --> 01:20:17,648 WITH SMALLER PROJECTS, AND THEN 1922 01:20:17,648 --> 01:20:21,753 AS THEY MATURE WE HOPE TO SEE 1923 01:20:21,753 --> 01:20:24,255 MORE R01-LEVEL FUNDING. 1924 01:20:24,255 --> 01:20:25,990 YOU NOTICE THERE ARE THREE 1925 01:20:25,990 --> 01:20:27,658 PRIMED PROJECTS WITH DATA 1926 01:20:27,658 --> 01:20:32,897 SCIENCE ELEMENTS THAT WE'RE 1927 01:20:32,897 --> 01:20:33,998 SUPPORTING, SO THERE'S GROWTH. 1928 01:20:33,998 --> 01:20:35,500 >> THANK YOU. 1929 01:20:35,500 --> 01:20:38,803 >> THANKS, PAUL. 1930 01:20:38,803 --> 01:20:39,003 AXEL? 1931 01:20:39,003 --> 01:20:40,571 >> YEAH, I DON'T REALLY HAVE A 1932 01:20:40,571 --> 01:20:47,578 QUESTION, JUST WANTED TO COMMENT 1933 01:20:47,578 --> 01:20:50,615 THAT SEEING SLIDES FROM THE NEW 1934 01:20:50,615 --> 01:20:52,817 NIH DIRECTOR, I THINK THEY 1935 01:20:52,817 --> 01:20:56,421 ALIGNED NICELY WITH SOME OF THE 1936 01:20:56,421 --> 01:20:58,289 CONCLUSIONS MADE IN OUR DATA 1937 01:20:58,289 --> 01:20:59,057 SCIENCE PROGRAM. 1938 01:20:59,057 --> 01:21:01,659 WE'RE TALKING ABOUT THAT IN MORE 1939 01:21:01,659 --> 01:21:04,328 DETAIL IN MY PRESENTATION BUT I 1940 01:21:04,328 --> 01:21:06,898 WAS REALLY EXCITED TO SEE THAT 1941 01:21:06,898 --> 01:21:09,667 DATA SCIENCE AND A.I.-DRIVEN 1942 01:21:09,667 --> 01:21:10,968 SOLUTIONS IN PARTICULAR WERE 1943 01:21:10,968 --> 01:21:14,705 CALLED OUT AT THIS LEVEL, AND 1944 01:21:14,705 --> 01:21:19,310 ALSO THE POTENTIAL FOR USING 1945 01:21:19,310 --> 01:21:21,712 THESE TO ADDRESS DISPARITIES IN 1946 01:21:21,712 --> 01:21:22,280 ACCESS. 1947 01:21:22,280 --> 01:21:22,613 >> ABSOLUTELY. 1948 01:21:22,613 --> 01:21:24,882 >> I JUST WANT TO SAY THIS IS 1949 01:21:24,882 --> 01:21:27,985 REALLY AN EXCITING DIRECTION I 1950 01:21:27,985 --> 01:21:28,186 THINK. 1951 01:21:28,186 --> 01:21:29,887 >> THANK YOU, AXEL. 1952 01:21:29,887 --> 01:21:31,789 THEY PAY DIRECTORS TO BE 1953 01:21:31,789 --> 01:21:32,090 VISIONARIES. 1954 01:21:32,090 --> 01:21:33,858 I FEEL THAT WHEN I TOOK THIS ON 1955 01:21:33,858 --> 01:21:35,526 THREE YEARS AGO THAT THIS WAS 1956 01:21:35,526 --> 01:21:38,563 COMING AND WE NEEDED IT. 1957 01:21:38,563 --> 01:21:40,531 SO BUT CONSTRUCTING A NEW OFFICE 1958 01:21:40,531 --> 01:21:42,166 WITHOUT HAVING THE WORKING GROUP 1959 01:21:42,166 --> 01:21:42,967 RECOMMENDATION, WITHOUT KNOWING 1960 01:21:42,967 --> 01:21:44,669 WHAT THE NEEDS ARE IS NOT THE 1961 01:21:44,669 --> 01:21:49,507 WISE THING TO DO SO WE'RE 1962 01:21:49,507 --> 01:21:51,042 BUILDING STEADFASTLY AND 1963 01:21:51,042 --> 01:21:52,443 SENSIBLY ESTABLISHING THIS 1964 01:21:52,443 --> 01:21:52,877 PRESENCE. 1965 01:21:52,877 --> 01:21:55,646 AND IT'S A HARD SCHISM TO 1966 01:21:55,646 --> 01:21:59,450 RECONCILE BECAUSE ON ONE HAND 1967 01:21:59,450 --> 01:22:01,786 YOU HAVE A BUDGET LOOM -- 1968 01:22:01,786 --> 01:22:03,020 RESTRAINING BUDGET LOOMING IN 1969 01:22:03,020 --> 01:22:05,356 THE DISTANCE, HOPEFULLY NOT AS 1970 01:22:05,356 --> 01:22:08,426 SEVERE AS IT COULD BE, THAT SAYS 1971 01:22:08,426 --> 01:22:12,363 DON'T INVEST IN THE BIG MONEY 1972 01:22:12,363 --> 01:22:12,864 INVESTMENTS. 1973 01:22:12,864 --> 01:22:15,333 YOU KNOW, BUT WHAT WE HAVE TO 1974 01:22:15,333 --> 01:22:16,968 MOVE FORWARD WITH COLLABORATION, 1975 01:22:16,968 --> 01:22:17,735 THERE'S OPPORTUNITIES AND 1976 01:22:17,735 --> 01:22:19,270 CHALLENGES SEEM TO MATCH EACH 1977 01:22:19,270 --> 01:22:22,106 OTHER, SO WE'RE GOING FORTH ARE 1978 01:22:22,106 --> 01:22:24,108 A LOT OF DETERMINATION, GRIT AND 1979 01:22:24,108 --> 01:22:24,942 DETERMINATION. 1980 01:22:24,942 --> 01:22:29,914 THANK YOU FOR ALL THE WORK 1981 01:22:29,914 --> 01:22:30,448 YOU'VE DONE. 1982 01:22:30,448 --> 01:22:30,648 JEFF? 1983 01:22:30,648 --> 01:22:33,851 >> THIS IS ALSO REGARDING THE 1984 01:22:33,851 --> 01:22:38,890 SECOND PART OF YOUR 1985 01:22:38,890 --> 01:22:40,825 PRESENTATION, RENA. 1986 01:22:40,825 --> 01:22:43,060 ABOUT PRIMED. 1987 01:22:43,060 --> 01:22:46,764 IS THERE ANY PLANS FOR A SECOND 1988 01:22:46,764 --> 01:22:52,003 REQUEST FOR APPLICATIONS FOR THE 1989 01:22:52,003 --> 01:22:52,470 PRIMED PROGRAM? 1990 01:22:52,470 --> 01:22:53,237 >> YES. 1991 01:22:53,237 --> 01:22:54,438 WE'RE CERTAINLY DRAWING THE 1992 01:22:54,438 --> 01:22:55,439 COMMUNITY TOGETHER FOR ALL THE 1993 01:22:55,439 --> 01:22:56,507 PRIMED P.I.s. 1994 01:22:56,507 --> 01:22:58,142 THAT'S THE FIRST STEP. 1995 01:22:58,142 --> 01:22:59,810 WE'RE GOING TO GAUGE PROGRESS, 1996 01:22:59,810 --> 01:23:02,847 WE'RE GOING TO GAUGE THE 1997 01:23:02,847 --> 01:23:04,282 POTENTIAL FOR TRANSFORMATIVE, 1998 01:23:04,282 --> 01:23:06,250 NOT JUST CULTURE BUT EXPERTISE 1999 01:23:06,250 --> 01:23:07,552 ACROSS THE SPECTRUM, AND WE 2000 01:23:07,552 --> 01:23:10,388 WOULD LIKE TO BE ABLE TO FUND, 2001 01:23:10,388 --> 01:23:13,424 REITERATE OR TO REISSUE AN RFA 2002 01:23:13,424 --> 01:23:16,327 WITH FOCUS ON CLINICAL TRIALS. 2003 01:23:16,327 --> 01:23:18,863 AND HAVE PRIMED IN THAT 2004 01:23:18,863 --> 01:23:19,297 DIRECTION. 2005 01:23:19,297 --> 01:23:22,567 I THINK IT'S JUST A PROSPECT. 2006 01:23:22,567 --> 01:23:24,335 WE WILL BE COMMUNICATING WITH 2007 01:23:24,335 --> 01:23:26,771 YOU HOPEFULLY MAY COUNCIL ABOUT 2008 01:23:26,771 --> 01:23:28,072 THAT INTENT, YEAH. 2009 01:23:28,072 --> 01:23:30,274 RIGHT NOW WE'RE IN THE WATCH, 2010 01:23:30,274 --> 01:23:33,477 LEARN, LISTEN MODE TO SEE HOW 2011 01:23:33,477 --> 01:23:35,346 THINGS ARE. 2012 01:23:35,346 --> 01:23:35,780 THANK YOU, JACQUES. 2013 01:23:35,780 --> 01:23:37,615 >> THAT WAS A GREAT TALK. 2014 01:23:37,615 --> 01:23:40,017 I HAVE A QUESTION ABOUT WHEN YOU 2015 01:23:40,017 --> 01:23:42,253 ARE TALKING ABOUT THE 2016 01:23:42,253 --> 01:23:43,854 INITIATIVES INVOLVING OTHER 2017 01:23:43,854 --> 01:23:44,155 INSTITUTES. 2018 01:23:44,155 --> 01:23:49,126 YOU MENTIONED ALSO THE HEAL 2019 01:23:49,126 --> 01:23:51,095 INITIATIVE IN COLLABORATION WITH 2020 01:23:51,095 --> 01:23:52,196 NIDA, NINDS. 2021 01:23:52,196 --> 01:23:55,032 I WONDER IF YOU COULD PROVIDE 2022 01:23:55,032 --> 01:24:00,938 MORE LIKE WHAT WOULD BE THE ROLE 2023 01:24:00,938 --> 01:24:02,673 OF THIS INSTITUTE IN THIS. 2024 01:24:02,673 --> 01:24:04,342 >> THAT'S A GOOD QUESTION. 2025 01:24:04,342 --> 01:24:07,945 WE DO HAVE PROPOSAL FUNDED 2026 01:24:07,945 --> 01:24:11,716 THROUGH "HEAL" ALREADY. 2027 01:24:11,716 --> 01:24:13,751 ON THE SMALLER SCALE. 2028 01:24:13,751 --> 01:24:15,720 THEIR BUDGET IS FLAT AS WELL. 2029 01:24:15,720 --> 01:24:17,121 ALL THE PROJECTS THAT WERE 2030 01:24:17,121 --> 01:24:21,425 COMING IN WITH CONSIDERED NOW 2031 01:24:21,425 --> 01:24:26,897 FOR THE FISCAL YEAR 25 CYCLE. 2032 01:24:26,897 --> 01:24:31,068 IF YOU HAVE AN IDEA IN MIND AND 2033 01:24:31,068 --> 01:24:32,903 WANT TO DEVELOP, THE MORE 2034 01:24:32,903 --> 01:24:35,339 COLLABORATIVE IT IS WITH OTHER 2035 01:24:35,339 --> 01:24:36,474 DISCIPLINES THE BETTER CHANCES. 2036 01:24:36,474 --> 01:24:42,880 "HEAL" IS MEANT TO BE 2037 01:24:42,880 --> 01:24:43,414 MULTI-DISCIPLINARY DRAWING 2038 01:24:43,414 --> 01:24:47,918 COLLABORATORS ACROSS THE BOARD, 2039 01:24:47,918 --> 01:24:48,786 ACROSS DISCIPLINES TO SOLVE A 2040 01:24:48,786 --> 01:24:49,687 PROBLEM. 2041 01:24:49,687 --> 01:24:53,090 "HEAL" IS NO LONGER LOCATED IN 2042 01:24:53,090 --> 01:24:55,826 THE DIRECTOR OFFICE BUT HANDLED 2043 01:24:55,826 --> 01:24:58,229 ON INSTITUTE LEVEL. 2044 01:24:58,229 --> 01:25:03,501 PAIN MANAGEMENT SPECTRUM DOMAIN 2045 01:25:03,501 --> 01:25:07,104 IS NINDS, HEADED BY WALTER 2046 01:25:07,104 --> 01:25:08,439 KOROSHETZ, I'M ON THE EXECUTIVE 2047 01:25:08,439 --> 01:25:08,773 COMMITTEE. 2048 01:25:08,773 --> 01:25:10,975 WE SHARED VISION AND GOALS 2049 01:25:10,975 --> 01:25:13,010 NICELY FOR THE FUTURE. 2050 01:25:13,010 --> 01:25:14,445 THE SUBSTANCE USE DISORDER, THE 2051 01:25:14,445 --> 01:25:17,181 OPIOID USE DISORDER FOR WHICH 2052 01:25:17,181 --> 01:25:19,383 "HEAL" WAS ACTUALLY CREATED, 2053 01:25:19,383 --> 01:25:20,284 RESIDES AT THE NATIONAL 2054 01:25:20,284 --> 01:25:22,019 INSTITUTE FOR DRUG ABUSE. 2055 01:25:22,019 --> 01:25:24,088 NOW, I WANT TO REMIND OUR 2056 01:25:24,088 --> 01:25:28,559 COMMUNITY THAT OPIOID USE 2057 01:25:28,559 --> 01:25:31,095 REMAINS STRONG AND THAT DENTISTS 2058 01:25:31,095 --> 01:25:33,898 REMAIN IN THE TOP PRESCRIBERS. 2059 01:25:33,898 --> 01:25:37,101 THERE ARE STUDIES HAPPENING, 2060 01:25:37,101 --> 01:25:42,373 RUTGERS, WONDERFUL STUDY, OTHERS 2061 01:25:42,373 --> 01:25:52,883 AS WELL, SHOWING IBUPROFEN IS 2062 01:25:54,652 --> 01:25:56,587 JUST AS EFFECTIVE. 2063 01:25:56,587 --> 01:25:58,322 LARGE COMMUNITY TESTING, 2064 01:25:58,322 --> 01:25:59,757 CLINICAL TRIALS ACTUALLY 2065 01:25:59,757 --> 01:26:01,892 INVOLVING THESE MEDICATIONS AND 2066 01:26:01,892 --> 01:26:04,028 COMPARING THEM IS IN THE WORKS. 2067 01:26:04,028 --> 01:26:07,198 IF YOU HAVE ANYTHING, I KNOW 2068 01:26:07,198 --> 01:26:09,367 THAT'S YOUR AREA, JOSE, PLEASE 2069 01:26:09,367 --> 01:26:12,803 DO WORK WITH US TO HELP YOU 2070 01:26:12,803 --> 01:26:14,004 POSITION FOR THE "HEAL" FUNDING. 2071 01:26:14,004 --> 01:26:14,739 >> DEFINITELY. 2072 01:26:14,739 --> 01:26:17,041 I FEEL LIKE INTERACTION AMONG 2073 01:26:17,041 --> 01:26:18,676 INSTITUTES IS KEY HERE, RIGHT? 2074 01:26:18,676 --> 01:26:22,413 YOU KNOW, IT'S NOT JUST LOOKING 2075 01:26:22,413 --> 01:26:24,715 AT OPIATE USE BY ITSELF, WHERE 2076 01:26:24,715 --> 01:26:26,250 ARE OPIATES COMING FROM, RIGHT? 2077 01:26:26,250 --> 01:26:29,954 AND OTHER PAIN IS MANAGED, WHAT 2078 01:26:29,954 --> 01:26:31,188 YOU'RE SAYING ABOUT DENTAL PAIN 2079 01:26:31,188 --> 01:26:37,728 IN MALES AND FEMALES, WOMEN AND 2080 01:26:37,728 --> 01:26:40,831 MEN, SOMETHING WE'RE SEEING. 2081 01:26:40,831 --> 01:26:43,200 >> YOU'RE AWARE OF BACPAC, 2082 01:26:43,200 --> 01:26:46,170 MUSCULOSKELETAL PAIN. 2083 01:26:46,170 --> 01:26:47,371 THESE INITIATIVES ARE 2084 01:26:47,371 --> 01:26:48,672 MULTI-DISCIPLINARY, AND THEY 2085 01:26:48,672 --> 01:26:50,307 INVOLVE DATA COORDINATION. 2086 01:26:50,307 --> 01:26:55,012 WE'RE NOW PLANNING IN THE SECOND 2087 01:26:55,012 --> 01:26:55,780 PHASE OF IMPACT, 2088 01:26:55,780 --> 01:26:57,047 TEMPOROMANDIBULAR DYSFUNCTION 2089 01:26:57,047 --> 01:26:59,517 PAIN, DRAWING FROM RESOURCES AND 2090 01:26:59,517 --> 01:27:00,951 BEST PRACTICES OF BACPAC IN 2091 01:27:00,951 --> 01:27:01,919 TERMS OF DATA COORDINATING 2092 01:27:01,919 --> 01:27:05,322 CENTER BECAUSE THAT'S AN 2093 01:27:05,322 --> 01:27:06,757 EXPENSIVE UNDERTAKING, THAT WE 2094 01:27:06,757 --> 01:27:08,826 DON'T HAVE RESOURCES FOR. 2095 01:27:08,826 --> 01:27:11,262 WE'RE WORKING AND HOPING AND 2096 01:27:11,262 --> 01:27:16,834 POSITIVE ABOUT HELP FROM NIDA, 2097 01:27:16,834 --> 01:27:18,335 NINDS, AND OTHER INSTITUTES. 2098 01:27:18,335 --> 01:27:25,042 >> HAPPY TO HELP ANY WAY I CAN. 2099 01:27:25,042 --> 01:27:27,545 >> THANK YOU. 2100 01:27:27,545 --> 01:27:31,282 I'M HAPPY TO SEE THE FACE OF 2101 01:27:31,282 --> 01:27:32,817 SOMEONE I'M DELIGHTED TO 2102 01:27:32,817 --> 01:27:36,086 INTRODUCE TO YOU. 2103 01:27:36,086 --> 01:27:39,557 OH, JENNIFER, MY LAST SLIDE, 2104 01:27:39,557 --> 01:27:44,295 SORRY. 2105 01:27:44,295 --> 01:27:47,832 DR. WOYCHIK'S SLIDE, GO TO THE 2106 01:27:47,832 --> 01:27:48,966 VERY END. 2107 01:27:48,966 --> 01:27:50,167 >> THE VERY LAST SLIDE. 2108 01:27:50,167 --> 01:27:51,435 >> HERE HE IS. 2109 01:27:51,435 --> 01:27:53,637 WHAT A NICE PICTURE OF YOU. 2110 01:27:53,637 --> 01:27:57,808 IT'S REALLY A PLEASURE TO HAVE 2111 01:27:57,808 --> 01:28:00,010 YOU ON BOARD. 2112 01:28:00,010 --> 01:28:02,513 INTERESTS, WE SHARE SO MANY IN 2113 01:28:02,513 --> 01:28:02,813 COMMON. 2114 01:28:02,813 --> 01:28:05,783 YOU COME WITH A GREAT 2115 01:28:05,783 --> 01:28:06,283 RESPONSIBILITY, SUPERB 2116 01:28:06,283 --> 01:28:07,885 BACKGROUND TO MOVE THE FIELD 2117 01:28:07,885 --> 01:28:11,288 FORWARD IN THE AREA OF 2118 01:28:11,288 --> 01:28:12,356 ENVIRONMENTAL HEALTH SCIENCES. 2119 01:28:12,356 --> 01:28:14,425 FOR US IN ORAL HEALTH, THE 2120 01:28:14,425 --> 01:28:17,728 INTERACTION BETWEEN GENES AND 2121 01:28:17,728 --> 01:28:20,231 ENVIRONMENT ARE CRITICAL. 2122 01:28:20,231 --> 01:28:22,099 ENVIRONMENTAL INCLUDES 2123 01:28:22,099 --> 01:28:22,366 NUTRITION. 2124 01:28:22,366 --> 01:28:24,301 REALLY DICTATES THE PROGRESS OF 2125 01:28:24,301 --> 01:28:26,704 CARIES AND PERIODONTAL DISEASE, 2126 01:28:26,704 --> 01:28:28,806 THE TWO MOST COMMON INFECTIOUS 2127 01:28:28,806 --> 01:28:30,641 DISEASES OF MANKIND. 2128 01:28:30,641 --> 01:28:33,210 I KNOW YOUR WISDOM, THAT YOU'RE 2129 01:28:33,210 --> 01:28:34,712 WILLING TO SHARE WITH US AND 2130 01:28:34,712 --> 01:28:37,248 HAVE YOU IN PLACE FUNDING 2131 01:28:37,248 --> 01:28:38,549 INITIATIVES THAT SHOULD APPEAL 2132 01:28:38,549 --> 01:28:40,518 TO SEVERAL OF OUR COLLEAGUES IN 2133 01:28:40,518 --> 01:28:40,985 THE FIELD. 2134 01:28:40,985 --> 01:28:43,687 I THANK YOU FOR YOUR FRIENDSHIP, 2135 01:28:43,687 --> 01:28:46,023 WHICH HAS BEEN STEADFAST AND 2136 01:28:46,023 --> 01:28:48,325 TRUE, AND FOR YOUR COLLEGIALITY 2137 01:28:48,325 --> 01:28:50,494 AS A FELLOW DIRECTOR. 2138 01:28:50,494 --> 01:28:52,897 THANK YOU, AND I'LL TURN IT OVER 2139 01:28:52,897 --> 01:28:53,130 TO YOU. 2140 01:28:53,130 --> 01:28:54,665 >> GREAT. 2141 01:28:54,665 --> 01:28:57,301 LET ME FIRST CHECK, CAN YOU HEAR 2142 01:28:57,301 --> 01:28:57,768 ME OKAY? 2143 01:28:57,768 --> 01:28:59,270 >> YES. 2144 01:28:59,270 --> 01:28:59,570 >> TERRIFIC. 2145 01:28:59,570 --> 01:29:01,338 RENA, THANK YOU. 2146 01:29:01,338 --> 01:29:04,241 YOU'RE A GREAT FRIEND. 2147 01:29:04,241 --> 01:29:06,443 IT'S JUST DELIGHTFUL TO HAVE 2148 01:29:06,443 --> 01:29:08,012 THIS OPPORTUNITY TO SHARE WITH 2149 01:29:08,012 --> 01:29:10,347 YOU SOME OF THE THINGS WE'RE 2150 01:29:10,347 --> 01:29:11,515 DOING HERE AT NIEHS. 2151 01:29:11,515 --> 01:29:13,250 I'M GOING TO BUILD ON SOME 2152 01:29:13,250 --> 01:29:15,419 DISCUSSIONS I JUST HEARD A FEW 2153 01:29:15,419 --> 01:29:16,987 MINUTES AGO ABOUT COLLABORATIONS 2154 01:29:16,987 --> 01:29:18,889 BETWEEN INSTITUTES AND CENTERS 2155 01:29:18,889 --> 01:29:20,024 ACROSS THE NIH BECAUSE I 2156 01:29:20,024 --> 01:29:23,093 THINK -- I KNOW RENA AND I BOTH 2157 01:29:23,093 --> 01:29:24,762 EMBRACE THAT CONCEPT. 2158 01:29:24,762 --> 01:29:26,497 WE WORK COLLABORATIVELY 2159 01:29:26,497 --> 01:29:27,965 TOGETHER, WE CAN ACCOMPLISH MORE 2160 01:29:27,965 --> 01:29:29,567 THAN ON OUR OWN. 2161 01:29:29,567 --> 01:29:34,171 SO LET ME START OFF HERE, IS 2162 01:29:34,171 --> 01:29:35,706 SOMEONE GOING TO SHARE MY SLIDE 2163 01:29:35,706 --> 01:29:36,006 DECK? 2164 01:29:36,006 --> 01:29:38,175 I UNDERSTAND YOU HAVE MY SLIDES. 2165 01:29:38,175 --> 01:29:41,378 >> YES, THEY SHOULD BE -- THERE 2166 01:29:41,378 --> 01:29:41,812 WE GO. 2167 01:29:41,812 --> 01:29:43,247 >> GREAT. 2168 01:29:43,247 --> 01:29:43,447 OKAY. 2169 01:29:43,447 --> 01:29:45,316 WELL, RENA AND I HAVE BEEN 2170 01:29:45,316 --> 01:29:49,019 TALKING A LOT ABOUT THE 2171 01:29:49,019 --> 01:29:50,020 COLLABORATIONS BETWEEN NIDCR AND 2172 01:29:50,020 --> 01:29:50,220 NIEHS. 2173 01:29:50,220 --> 01:29:52,489 SO I THOUGHT I WOULD FOCUS ON IN 2174 01:29:52,489 --> 01:29:54,959 THE BRIEF TIME I HAVE WITH YOU 2175 01:29:54,959 --> 01:29:57,494 SOME RESEARCH PRIORITIES AT 2176 01:29:57,494 --> 01:29:57,928 NIEHS. 2177 01:29:57,928 --> 01:29:59,997 SO BEFORE I GO INTO THAT THOUGH 2178 01:29:59,997 --> 01:30:01,465 I THOUGHT IT WOULD BE GOOD TO 2179 01:30:01,465 --> 01:30:04,034 SHARE WITH YOU A LITTLE BIT OF 2180 01:30:04,034 --> 01:30:07,471 OUR INSTITUTE. 2181 01:30:07,471 --> 01:30:08,739 NEXT SLIDE. 2182 01:30:08,739 --> 01:30:10,507 OF THE 27 INSTITUTES AND CENTERS 2183 01:30:10,507 --> 01:30:12,810 THAT ARE PART OF THE NATIONAL 2184 01:30:12,810 --> 01:30:15,079 INSTITUTES OF HEALTH WE'RE 2185 01:30:15,079 --> 01:30:16,747 LOCATED -- WE'RE THE ONLY 2186 01:30:16,747 --> 01:30:17,514 INSTITUTE THAT'S NOT 2187 01:30:17,514 --> 01:30:18,949 HEADQUARTERED IN THE GREATER 2188 01:30:18,949 --> 01:30:20,384 WASHINGTON, D.C. AREA. 2189 01:30:20,384 --> 01:30:22,686 SO WE'RE LOCATED IN CENTRAL 2190 01:30:22,686 --> 01:30:23,554 NORTH CAROLINA, IN RESEARCH 2191 01:30:23,554 --> 01:30:25,623 TRIANGLE PARK, SOUTH OF DURHAM, 2192 01:30:25,623 --> 01:30:27,758 NORTH CAROLINA. 2193 01:30:27,758 --> 01:30:29,026 WHY ARE WE THERE? 2194 01:30:29,026 --> 01:30:30,661 IT'S A GOOD SCIENCE REASON AND 2195 01:30:30,661 --> 01:30:31,261 GOOD POLITICAL REASON. 2196 01:30:31,261 --> 01:30:34,832 LET ME START WITH THE SCIENCE 2197 01:30:34,832 --> 01:30:35,065 REASON. 2198 01:30:35,065 --> 01:30:37,267 SO, OUR INSTITUTE, NEXT SLIDE, 2199 01:30:37,267 --> 01:30:39,103 WE'RE DEDICATED TO PUBLIC HEALTH 2200 01:30:39,103 --> 01:30:42,506 AND PREVENTION OF -- NOT YET, 2201 01:30:42,506 --> 01:30:43,807 SORRY. 2202 01:30:43,807 --> 01:30:45,042 WE'RE DEDICATED TO PUBLIC 2203 01:30:45,042 --> 01:30:47,311 HEALTH, SO IF THE NIH IS GOING 2204 01:30:47,311 --> 01:30:48,746 TO LOCATE AN INSTITUTE DEDICATED 2205 01:30:48,746 --> 01:30:52,082 TO PUBLIC HEALTH, WHY NOT PUT IT 2206 01:30:52,082 --> 01:30:53,250 ADJACENT TO THE UNIVERSITY OF 2207 01:30:53,250 --> 01:30:54,018 NORTH CAROLINA'S SCHOOL OF 2208 01:30:54,018 --> 01:30:55,886 PUBLIC HEALTH, WHICH IS ONE OF 2209 01:30:55,886 --> 01:30:57,087 THE BEST IN THE COUNTRY. 2210 01:30:57,087 --> 01:30:59,723 OF COURSE, WE HAVE AN INTEREST, 2211 01:30:59,723 --> 01:31:01,291 THE NAME WOULD IMPLY, IN THE 2212 01:31:01,291 --> 01:31:02,860 ENVIRONMENT, AND IT WOULD BE 2213 01:31:02,860 --> 01:31:05,362 GREAT TO BE LOCATED IN THE 2214 01:31:05,362 --> 01:31:06,830 VICINITY OF THE DUKE UNIVERSITY 2215 01:31:06,830 --> 01:31:08,966 WITH ITS VERY STRONG PROGRAM IN 2216 01:31:08,966 --> 01:31:11,101 THE ENVIRONMENT, AND OF COURSE 2217 01:31:11,101 --> 01:31:12,736 WITH OUR FOCUS IN TOXICOLOGY 2218 01:31:12,736 --> 01:31:15,506 SCIENCE WHY NOT PUT US ADJACENT 2219 01:31:15,506 --> 01:31:16,674 TO NORTH CAROLINA STATE 2220 01:31:16,674 --> 01:31:19,410 UNIVERSITY, WHICH HAS A VERY 2221 01:31:19,410 --> 01:31:21,512 STRONG INTERDEPARTMENTAL PROGRAM 2222 01:31:21,512 --> 01:31:22,479 IN TOXICOLOGY SCIENCE. 2223 01:31:22,479 --> 01:31:25,883 SO, THIS IS THE IDEAL PLACE TO 2224 01:31:25,883 --> 01:31:27,217 BE, WITH OUR INTERESTS THAT 2225 01:31:27,217 --> 01:31:28,419 DOVETAIL WITH THE INTEREST OF 2226 01:31:28,419 --> 01:31:30,754 SOME OF THE BEST ACADEMIC 2227 01:31:30,754 --> 01:31:32,790 ORGANIZATIONS IN CENTRAL NORTH 2228 01:31:32,790 --> 01:31:33,223 CAROLINA. 2229 01:31:33,223 --> 01:31:34,324 NOW, THE REAL REASON WE'RE HERE 2230 01:31:34,324 --> 01:31:36,927 IS THAT THE GOVERNOR OF NORTH 2231 01:31:36,927 --> 01:31:38,796 CAROLINA DELIVERED NORTH 2232 01:31:38,796 --> 01:31:40,898 CAROLINA TO THE KENNEDY, IN THE 2233 01:31:40,898 --> 01:31:42,966 1960 ELECTION, SO THE GOVERNOR 2234 01:31:42,966 --> 01:31:45,436 HAD THIS BOLD VISION TO 2235 01:31:45,436 --> 01:31:47,705 ESSENTIALLY CREATE SILICON 2236 01:31:47,705 --> 01:31:48,372 VALLEY OF NORTH CAROLINA, 2237 01:31:48,372 --> 01:31:50,441 RESEARCH TRIANGLE PARK, HE 2238 01:31:50,441 --> 01:31:52,276 NEEDED AN ANCHOR TENANT. 2239 01:31:52,276 --> 01:31:56,547 WELL, WE'RE THE ANCHOR TENANT. 2240 01:31:56,547 --> 01:31:58,282 WE STARTED IN CENTRAL NORTH 2241 01:31:58,282 --> 01:32:00,684 CAROLINA, YOU CAN SEE OUR 2242 01:32:00,684 --> 01:32:04,521 CURRENT BUILDINGS THAT WE HAVE. 2243 01:32:04,521 --> 01:32:08,358 AND RENA, WE'RE LOOKING FORWARD 2244 01:32:08,358 --> 01:32:09,326 TO GETTING YOU DOWN HERE. 2245 01:32:09,326 --> 01:32:10,627 LIKE MANY OF THE OTHER 2246 01:32:10,627 --> 01:32:12,596 INSTITUTES AND CENTERS WE HAVE 2247 01:32:12,596 --> 01:32:14,264 OUR INTRAMURAL PROGRAMS AND WE 2248 01:32:14,264 --> 01:32:15,799 HAVE THE EXTRAMURAL DIVISION 2249 01:32:15,799 --> 01:32:17,668 WHERE WE BUNDLE MOST OF THE -- 2250 01:32:17,668 --> 01:32:19,303 THE BUDGET IS ABOUT A BILLION 2251 01:32:19,303 --> 01:32:20,604 DOLLARS, WE BUNDLE MOST UP IN 2252 01:32:20,604 --> 01:32:23,707 THE FORM OF CONTRACTS AND GRANTS 2253 01:32:23,707 --> 01:32:24,842 TO THE EXTRAMURAL COMMUNITY. 2254 01:32:24,842 --> 01:32:27,377 BUT I ALSO WANT TO POINT OUT 2255 01:32:27,377 --> 01:32:30,147 THAT WE HAVE A SECOND INTRAMURAL 2256 01:32:30,147 --> 01:32:31,115 RESEARCH PROGRAM, NATIONAL 2257 01:32:31,115 --> 01:32:32,182 TOXICOLOGY PROGRAM. 2258 01:32:32,182 --> 01:32:34,818 IT'S CALLED THE DIVISION OF 2259 01:32:34,818 --> 01:32:35,719 TRANSLATIONAL TOXICOLOGY. 2260 01:32:35,719 --> 01:32:36,787 THAT'S MY SECOND ROLE. 2261 01:32:36,787 --> 01:32:38,889 I'M NOT JUST THE DIRECTOR OF 2262 01:32:38,889 --> 01:32:41,725 NIEHS BUT ALSO DIRECTOR OF THIS 2263 01:32:41,725 --> 01:32:45,629 VIRTUAL COLLABORATION WITH THE 2264 01:32:45,629 --> 01:32:47,631 FDA AND CDC. 2265 01:32:47,631 --> 01:32:49,266 SO THAT'S THE NATIONAL 2266 01:32:49,266 --> 01:32:50,934 TOXICOLOGY PROGRAM. 2267 01:32:50,934 --> 01:32:54,304 SO, WE HAVE A NUMBER OF 2268 01:32:54,304 --> 01:32:55,172 INTRAMURAL RESEARCH 2269 01:32:55,172 --> 01:32:58,142 LABORATORIES, DO THINGS SIMILAR 2270 01:32:58,142 --> 01:33:06,049 TO DCR AND OTHER INSTITUTES AND 2271 01:33:06,049 --> 01:33:07,317 CENTERS ACROSS THE NIH. 2272 01:33:07,317 --> 01:33:11,155 WHAT WE DO GOES BACK TO OUR 2273 01:33:11,155 --> 01:33:12,556 MISSION, TO DISCOVER HOW 2274 01:33:12,556 --> 01:33:14,558 ENVIRONMENT AFFECTS PEOPLE TO 2275 01:33:14,558 --> 01:33:15,292 PROMOTE HEALTHIER LIVES, THERE 2276 01:33:15,292 --> 01:33:16,827 LOTS OF THINGS IN THE 2277 01:33:16,827 --> 01:33:18,095 ENVIRONMENT, SOME BAD THINGS AND 2278 01:33:18,095 --> 01:33:20,898 GOOD THINGS IN THE ENVIRONMENT 2279 01:33:20,898 --> 01:33:21,799 THAT CAN ULTIMATELY PROMOTE 2280 01:33:21,799 --> 01:33:22,900 HEALTHIER LIVES. 2281 01:33:22,900 --> 01:33:24,301 WE'RE INTERESTED IN THOSE. 2282 01:33:24,301 --> 01:33:27,337 AND THE VISION FOR NIEHS IS TO 2283 01:33:27,337 --> 01:33:28,438 PROVIDE GLOBAL LEADERSHIP FOR 2284 01:33:28,438 --> 01:33:29,673 INNOVATIVE RESEARCH THAT 2285 01:33:29,673 --> 01:33:31,208 IMPROVES PUBLIC HEALTH BY 2286 01:33:31,208 --> 01:33:32,810 PREVENTING DISEASE AND 2287 01:33:32,810 --> 01:33:34,378 DISABILITY. 2288 01:33:34,378 --> 01:33:36,446 SO I THINK WE SHARE THIS 2289 01:33:36,446 --> 01:33:38,315 PREVENTION CONCEPT THAT IF WE 2290 01:33:38,315 --> 01:33:39,283 CAN IDENTIFY SOME OF THOSE BAD 2291 01:33:39,283 --> 01:33:40,350 THINGS IN THE ENVIRONMENT OR 2292 01:33:40,350 --> 01:33:42,486 SOME GOOD THINGS IN THE 2293 01:33:42,486 --> 01:33:44,021 ENVIRONMENT CAN WE BE PROMOTING 2294 01:33:44,021 --> 01:33:45,789 THAT TO PROMOTE PUBLIC HEALTH IN 2295 01:33:45,789 --> 01:33:48,192 A WAY THAT PREVENTS DISEASE AND 2296 01:33:48,192 --> 01:33:48,492 DISABILITY? 2297 01:33:48,492 --> 01:33:55,866 SO LET'S GO TO THE NEXT SLIDE. 2298 01:33:55,866 --> 01:33:56,800 SO I'M CURRENTLY LEADING THE 2299 01:33:56,800 --> 01:33:58,035 NEXT VERSION OF OUR STRATEGIC 2300 01:33:58,035 --> 01:33:58,235 PLAN. 2301 01:33:58,235 --> 01:33:59,236 WE HOPEFULLY WILL BE ROLLING 2302 01:33:59,236 --> 01:34:02,873 THIS OUT IN THE NEXT FEW MONTHS. 2303 01:34:02,873 --> 01:34:04,741 AND WE'VE BEEN REACHING OUT TO 2304 01:34:04,741 --> 01:34:06,577 THE GLOBAL COMMUNITY FOR INPUT, 2305 01:34:06,577 --> 01:34:08,779 AND WHAT ARE SOME OF THE 2306 01:34:08,779 --> 01:34:09,513 IMPORTANT SCIENTIFIC PRIORITY 2307 01:34:09,513 --> 01:34:11,381 AREAS THAT NEED TO BE INTEGRAL 2308 01:34:11,381 --> 01:34:13,283 TO OUR NEXT STRATEGIC PLAN? 2309 01:34:13,283 --> 01:34:15,919 SO, SIX OF THESE HAVE EMERGED. 2310 01:34:15,919 --> 01:34:17,821 AND SO THEY ARE SHOWN ON THE 2311 01:34:17,821 --> 01:34:19,022 SLIDE HERE. 2312 01:34:19,022 --> 01:34:20,991 SO WE HAVE THIS CONCEPT OF 2313 01:34:20,991 --> 01:34:21,558 EXPOSOME. 2314 01:34:21,558 --> 01:34:23,160 I'LL TALK ABOUT THAT FIRST IN A 2315 01:34:23,160 --> 01:34:24,428 COUPLE MINUTES. 2316 01:34:24,428 --> 01:34:27,364 ALSO THIS CONCEPT OF PRECISION 2317 01:34:27,364 --> 01:34:29,233 ENVIRONMENTAL HEALTH. 2318 01:34:29,233 --> 01:34:30,467 THAT REFERS TO SOME OF THE 2319 01:34:30,467 --> 01:34:34,371 COMMENTS RENA MADE AT THE 2320 01:34:34,371 --> 01:34:34,605 OUTSIDE. 2321 01:34:34,605 --> 01:34:35,706 IT'S NOT JUST ENVIRONMENT OR 2322 01:34:35,706 --> 01:34:37,574 GENETICS BUT IN MANY CASES A 2323 01:34:37,574 --> 01:34:38,642 COMBINATION OF BOTH. 2324 01:34:38,642 --> 01:34:40,944 WE ALSO HAVE A FOCUS ON 2325 01:34:40,944 --> 01:34:43,480 MECHANISTIC AND TRANSLATIONAL 2326 01:34:43,480 --> 01:34:43,981 BIOLOGY AND TOXICOLOGY. 2327 01:34:43,981 --> 01:34:47,184 AND SO THIS IS WHERE WE'RE 2328 01:34:47,184 --> 01:34:50,153 REALLY GETTING BEYOND JUST 2329 01:34:50,153 --> 01:34:52,990 TAKING OUTBRED RATS OR MICE, 2330 01:34:52,990 --> 01:34:57,895 INJECTING THEM WITH CHEMICALS 2331 01:34:57,895 --> 01:34:59,229 AND DETERMINING LUMP, BUMPS, 2332 01:34:59,229 --> 01:34:59,963 DEATHS. 2333 01:34:59,963 --> 01:35:01,298 WE WANT TO EXPLORE MECHANISMS 2334 01:35:01,298 --> 01:35:03,166 THROUGH WHICH DIFFERENT 2335 01:35:03,166 --> 01:35:03,934 ENVIRONMENTAL AGENTS CAN AFFECT 2336 01:35:03,934 --> 01:35:06,870 HOW GENES ARE EXPRESSED AND 2337 01:35:06,870 --> 01:35:09,840 AFFECT HUMAN BIOLOGY. 2338 01:35:09,840 --> 01:35:12,142 WE ALSO HAVE NIH-WIDE EFFORT ON 2339 01:35:12,142 --> 01:35:13,343 CLIMATE CHANGE AND HEALTH. 2340 01:35:13,343 --> 01:35:15,212 WE HAVE A FOCUS ON ENVIRONMENTAL 2341 01:35:15,212 --> 01:35:16,647 JUSTICE AND HEALTH DISPARITIES. 2342 01:35:16,647 --> 01:35:18,715 AND OF COURSE LIKE MANY OF THE 2343 01:35:18,715 --> 01:35:21,652 OTHER INSTITUTES AT THE NIH 2344 01:35:21,652 --> 01:35:22,786 THERE'S FOCUS ON COMPUTATIONAL 2345 01:35:22,786 --> 01:35:25,722 BIOLOGY AND DATA SCIENCE. 2346 01:35:25,722 --> 01:35:26,456 BIOLOGY IS BECOMING INCREASINGLY 2347 01:35:26,456 --> 01:35:28,558 COMPUTATIONAL IN NATURE SO 2348 01:35:28,558 --> 01:35:30,861 FIGURING HOW TO DO WE MANAGE 2349 01:35:30,861 --> 01:35:31,395 HUGE DATASETS, ESPECIALLY 2350 01:35:31,395 --> 01:35:33,363 COLLECTED ON A GLOBAL BASIS. 2351 01:35:33,363 --> 01:35:35,766 HOW DO WE MANAGE IN A WAY 2352 01:35:35,766 --> 01:35:37,234 EVERYONE CAN BE TAKING ADVANTAGE 2353 01:35:37,234 --> 01:35:39,269 OF THE DATA THAT IS BEING 2354 01:35:39,269 --> 01:35:40,137 PRODUCED BY OTHERS? 2355 01:35:40,137 --> 01:35:42,005 SO THESE ARE THE BIG CHALLENGES. 2356 01:35:42,005 --> 01:35:43,040 IN THE LIMITED TIME I HAVE, I'M 2357 01:35:43,040 --> 01:35:44,641 NOT GOING TO BE ABLE TO GET 2358 01:35:44,641 --> 01:35:45,275 THROUGH ALL. 2359 01:35:45,275 --> 01:35:47,144 I'VE GOT SLIDES FOR ALL BUT I 2360 01:35:47,144 --> 01:35:48,779 THINK WE'LL BE ABLE TO GET 2361 01:35:48,779 --> 01:35:50,247 THROUGH THE EXPOSOME AND 2362 01:35:50,247 --> 01:35:50,881 PRECISION ENVIRONMENTAL HEALTH, 2363 01:35:50,881 --> 01:35:53,717 I WANT TO HAVE PLENTY OF TIME TO 2364 01:35:53,717 --> 01:35:54,685 ENGAGE IN Q&A. 2365 01:35:54,685 --> 01:35:57,854 LET'S GO TO THE NEXT SLIDE. 2366 01:35:57,854 --> 01:36:00,624 LET'S TALK ABOUT THE EXPOSOME. 2367 01:36:00,624 --> 01:36:02,559 WHAT IS THE EXPOSOME? 2368 01:36:02,559 --> 01:36:04,861 THIS IS A CONCEPT THAT WAS 2369 01:36:04,861 --> 01:36:07,297 ORIGINALLY PROPOSED BY CHRIS 2370 01:36:07,297 --> 01:36:09,933 WILD IN 2005, RIGHT AFTER THE 2371 01:36:09,933 --> 01:36:11,768 FIRST PHASE OF COMPLETION OF 2372 01:36:11,768 --> 01:36:13,136 HUMAN GENOME PROJECT. 2373 01:36:13,136 --> 01:36:16,807 JUST LIKE THE HUMAN GENOME 2374 01:36:16,807 --> 01:36:18,342 PROJECT, THE EXPOSOME OF THE 2375 01:36:18,342 --> 01:36:19,776 HUMAN GENOME PROJECT IS GETTING 2376 01:36:19,776 --> 01:36:21,611 BEYOND ONE GENE AT A TIME TO 2377 01:36:21,611 --> 01:36:23,280 STUDY ALL THE GENES, SO CHRIS 2378 01:36:23,280 --> 01:36:25,015 WILD PROPOSED THAT IF WE TRULY 2379 01:36:25,015 --> 01:36:26,783 WANT TO UNDERSTAND THE IMPACT OF 2380 01:36:26,783 --> 01:36:29,286 THE ENVIRONMENT, WE HAVE TO GET 2381 01:36:29,286 --> 01:36:30,520 BEYOND STUDYING ONE EXPOSURE AT 2382 01:36:30,520 --> 01:36:31,822 A TIME. 2383 01:36:31,822 --> 01:36:33,223 BECAUSE THE REALITY IS THAT 2384 01:36:33,223 --> 01:36:35,525 WE'RE EXPOSED TO ALL SORTS OF 2385 01:36:35,525 --> 01:36:37,394 DIFFERENT THINGS AT THE SAME 2386 01:36:37,394 --> 01:36:37,861 TIME. 2387 01:36:37,861 --> 01:36:41,431 SO IN THE LOWER PANEL HERE IN 2388 01:36:41,431 --> 01:36:45,602 THE DARK BLUE BOX, WE'RE EXPOSED 2389 01:36:45,602 --> 01:36:48,438 TO PESTICIDES, WE'RE EXPOSED 2390 01:36:48,438 --> 01:36:50,307 REMARKABLY WHEN YOU DRINK WATER 2391 01:36:50,307 --> 01:37:00,817 OUT OF THE ALUMINUM CAN, BIS 2392 01:37:05,589 --> 01:37:07,924 PHENOL IS LEACHING, TEFLONS, 2393 01:37:07,924 --> 01:37:09,159 SCOTCH GUARDS, BIOLOGICAL 2394 01:37:09,159 --> 01:37:11,094 CONSEQUENCES OF BEING EXPOSED TO 2395 01:37:11,094 --> 01:37:11,595 THIS. 2396 01:37:11,595 --> 01:37:12,529 WE'RE EXPOSED TO ALL THESE 2397 01:37:12,529 --> 01:37:14,698 THINGS, IF WE WANT TO UNDERSTAND 2398 01:37:14,698 --> 01:37:15,932 THE ENVIRONMENT IT CAN'T BE JUST 2399 01:37:15,932 --> 01:37:16,366 ONE THING. 2400 01:37:16,366 --> 01:37:19,102 WE NEED TO DEVELOP A RESEARCH 2401 01:37:19,102 --> 01:37:20,871 STRATEGY THAT FACTORS IN ALL OF 2402 01:37:20,871 --> 01:37:22,406 THESE DIFFERENT THINGS. 2403 01:37:22,406 --> 01:37:24,174 SO THAT'S THE EXPOSOME. 2404 01:37:24,174 --> 01:37:27,677 I ALSO WANT -- THIS IS VERY 2405 01:37:27,677 --> 01:37:29,946 IMPORTANT, IT'S ALSO ABOUT 2406 01:37:29,946 --> 01:37:32,682 INTEGRATING SOCIAL ECOSYSTEM AND 2407 01:37:32,682 --> 01:37:34,551 LIFESTYLE VARIABLE, NOT JUST 2408 01:37:34,551 --> 01:37:35,419 PHYSICAL CHEMICAL EFFECTS. 2409 01:37:35,419 --> 01:37:37,120 SO WE KNOW AS RENA INDICATED 2410 01:37:37,120 --> 01:37:39,489 DIET IS REALLY IMPORTANT. 2411 01:37:39,489 --> 01:37:41,892 GOOD DIET IS GOOD. 2412 01:37:41,892 --> 01:37:44,194 A BAD DIET CAN PROMOTE DENTAL 2413 01:37:44,194 --> 01:37:46,930 CARIES, BAD ORAL HEALTH, AND 2414 01:37:46,930 --> 01:37:48,098 OTHER DELETERIOUS HEALTH 2415 01:37:48,098 --> 01:37:48,999 EFFECTS. 2416 01:37:48,999 --> 01:37:51,301 GOOD SLEEP BEHAVIOR OR BAD SLEEP 2417 01:37:51,301 --> 01:37:52,836 BEHAVIOR HAS TO BE FACTORED IN 2418 01:37:52,836 --> 01:37:55,539 WHEN WE STUDY THE EXPOSOME. 2419 01:37:55,539 --> 01:37:56,840 PHYSICAL ACTIVITY, EXERCISE, IN 2420 01:37:56,840 --> 01:38:00,377 FACT SOME OF OUR GRANTEES ARE 2421 01:38:00,377 --> 01:38:02,212 DETERMINING THAT THERE ARE 2422 01:38:02,212 --> 01:38:03,847 POSITIVE EFFECTS OF, SAY, 2423 01:38:03,847 --> 01:38:06,249 PHYSICAL ACTIVITY OR DIET, GOOD 2424 01:38:06,249 --> 01:38:12,089 SLEEP, MITIGATE SOME OF THE 2425 01:38:12,089 --> 01:38:12,989 DELETERIOUS EFFECTS FROM SOME 2426 01:38:12,989 --> 01:38:13,824 CHEMICAL EXPOSURE ON LOWER 2427 01:38:13,824 --> 01:38:14,024 PANEL. 2428 01:38:14,024 --> 01:38:15,125 WE THINK ABOUT THE ENVIRONMENT, 2429 01:38:15,125 --> 01:38:18,361 WE HAVE TO THINK IN THE CONTEXT 2430 01:38:18,361 --> 01:38:21,598 OF THE EXPOSOME FRAMEWORK. 2431 01:38:21,598 --> 01:38:28,071 NOW, THE CHALLENGE IS, NEXT 2432 01:38:28,071 --> 01:38:30,507 SLIDE, SO HOW DO WE DO AN 2433 01:38:30,507 --> 01:38:31,575 EXPOSOME EXPERIMENT? 2434 01:38:31,575 --> 01:38:33,243 THAT'S A QUESTION FRANCIS 2435 01:38:33,243 --> 01:38:34,978 COLLINS HAS SOON AFTER HE BECAME 2436 01:38:34,978 --> 01:38:35,412 DIRECTOR. 2437 01:38:35,412 --> 01:38:38,281 IT'S EASY TO USE THE TERM 2438 01:38:38,281 --> 01:38:40,884 EXPOSOME BUT HOW DO WE DO AN 2439 01:38:40,884 --> 01:38:43,453 EXPOSOME EXPERIMENT AND MEASURE 2440 01:38:43,453 --> 01:38:44,488 THE TOTALITY OF EXPOSURES. 2441 01:38:44,488 --> 01:38:47,257 IN FACT PART OF THE EXPOSOME TOO 2442 01:38:47,257 --> 01:38:49,759 IS ALSO LOOKING AT THE TIME 2443 01:38:49,759 --> 01:38:50,360 COURSE. 2444 01:38:50,360 --> 01:38:52,496 THERE ARE CRITICAL EXPOSURES 2445 01:38:52,496 --> 01:38:53,697 THAT HAPPEN, FOR EXAMPLE, DURING 2446 01:38:53,697 --> 01:38:56,533 DEVELOPMENT THAT MAY BE 2447 01:38:56,533 --> 01:38:58,235 CRITICALLY IMPORTANT FOR THE 2448 01:38:58,235 --> 01:39:00,470 HEALTH OF THE FETUS. 2449 01:39:00,470 --> 01:39:05,509 NOT JUST DURING DEVELOPMENT BUT 2450 01:39:05,509 --> 01:39:08,712 THEY MAY BE RESETTING EPIGENOME 2451 01:39:08,712 --> 01:39:09,913 HOW GENES ARE EXPRESSED IN THE 2452 01:39:09,913 --> 01:39:11,648 LIFE COURSE. 2453 01:39:11,648 --> 01:39:12,749 WE NEED AN OPERATIONAL 2454 01:39:12,749 --> 01:39:15,152 DEFINITION OF EXPOSOME. 2455 01:39:15,152 --> 01:39:16,653 FURTHERMORE, IT CAN'T BE JUST 2456 01:39:16,653 --> 01:39:17,454 MEASURING THINGS IN THE 2457 01:39:17,454 --> 01:39:20,724 ENVIRONMENT, CHEMICALS IN THE 2458 01:39:20,724 --> 01:39:21,625 ENVIRONMENT, AIR POLLUTION, 2459 01:39:21,625 --> 01:39:22,926 PARTICULATE MATTER, SLEEP AND 2460 01:39:22,926 --> 01:39:24,594 OTHER THINGS. 2461 01:39:24,594 --> 01:39:26,663 BUT WE ALSO NEED TO DEVELOP 2462 01:39:26,663 --> 01:39:30,167 STRATEGY WHERE WE CAN MEASURE 2463 01:39:30,167 --> 01:39:32,669 BIOLOGICAL RESPONSES TO THESE 2464 01:39:32,669 --> 01:39:33,170 ENVIRONMENTAL EXPOSURES, 2465 01:39:33,170 --> 01:39:34,304 TOTALITY OF EXPOSURES, THAT'S AN 2466 01:39:34,304 --> 01:39:35,739 AREA, FOR EXAMPLE, THAT I'M 2467 01:39:35,739 --> 01:39:40,143 PERSONALLY VERY INTERESTED IN. 2468 01:39:40,143 --> 01:39:42,312 HOW DO EXPOSOMIC INFLUENCES 2469 01:39:42,312 --> 01:39:45,148 CHANGE THE EPIGENETIC STATUS OF 2470 01:39:45,148 --> 01:39:47,117 AN INDIVIDUAL'S GENOME IN A WAY 2471 01:39:47,117 --> 01:39:49,085 THAT COULD INFLUENCE HOW GENES 2472 01:39:49,085 --> 01:39:49,519 ARE WORKING? 2473 01:39:49,519 --> 01:39:51,955 WHAT'S CLEAR IS WE'LL HAVE TO 2474 01:39:51,955 --> 01:39:53,690 DEVELOP SOME NEW TECHNOLOGIES. 2475 01:39:53,690 --> 01:39:55,125 SO ONE THING THAT'S EMERGING NOW 2476 01:39:55,125 --> 01:39:56,893 IN THE ENVIRONMENTAL HEALTH 2477 01:39:56,893 --> 01:39:59,062 SCIENCES COMMUNITY IS IDEA OF 2478 01:39:59,062 --> 01:40:03,333 TAKING A SMALL VOLUME OF BLOOD 2479 01:40:03,333 --> 01:40:05,068 AND USING HIGH RESOLUTION MASS 2480 01:40:05,068 --> 01:40:06,303 SPECTROMETRY, SOMETHING WE 2481 01:40:06,303 --> 01:40:06,937 CALLED PRAGMATIC EXPOSOME, 2482 01:40:06,937 --> 01:40:09,039 THINGS WE CAN DO WITH 2483 01:40:09,039 --> 01:40:10,574 TECHNOLOGIES WE HAVE CURRENTLY 2484 01:40:10,574 --> 01:40:10,840 AVAILABLE. 2485 01:40:10,840 --> 01:40:14,611 BUT WE'RE GOING TO NEED NEW 2486 01:40:14,611 --> 01:40:15,278 TECHNOLOGY, HIGHER THROUGHPUT, 2487 01:40:15,278 --> 01:40:16,379 LOWER COST TECHNOLOGIES TO 2488 01:40:16,379 --> 01:40:20,417 ENABLE SOME THINGS TO HAPPEN. 2489 01:40:20,417 --> 01:40:21,851 SO, AS GENETICS AND GENOMICS 2490 01:40:21,851 --> 01:40:23,620 PERSON I MODEL WHAT WE'RE DOING 2491 01:40:23,620 --> 01:40:26,356 IN EXPOSOMICS TO WHAT'S 2492 01:40:26,356 --> 01:40:28,425 HAPPENING IN THE GENOMICS 2493 01:40:28,425 --> 01:40:29,192 COMMUNITY. 2494 01:40:29,192 --> 01:40:30,694 WE STARTED OFF THE GENOME 2495 01:40:30,694 --> 01:40:32,896 PROJECT STARTED WITH A BOLD 2496 01:40:32,896 --> 01:40:35,865 VISION, BACK IN THE EARLY 2497 01:40:35,865 --> 01:40:37,834 1980s, AND THEN OVER THE 2498 01:40:37,834 --> 01:40:40,270 COURSE OF TIME NEW TECHNOLOGIES 2499 01:40:40,270 --> 01:40:42,339 WERE DEVELOPED TO ALLOW US TO 2500 01:40:42,339 --> 01:40:44,541 ACTUALLY ACHIEVE THAT END GOAL 2501 01:40:44,541 --> 01:40:46,176 OF SEQUENCING THE ENTIRE HUMAN 2502 01:40:46,176 --> 01:40:47,811 GENOME AND DEVELOPING A WHOLE 2503 01:40:47,811 --> 01:40:49,279 SUITE OF DIFFERENT TECHNOLOGIES 2504 01:40:49,279 --> 01:40:52,749 THAT ALLOW US TO DO GENETICS AND 2505 01:40:52,749 --> 01:40:54,251 GENOMICS IN A WAY THAT I DON'T 2506 01:40:54,251 --> 01:40:56,353 THINK WE WOULD HAVE IMAGINED IN 2507 01:40:56,353 --> 01:40:57,120 THE EARLY 1980s. 2508 01:40:57,120 --> 01:40:58,989 LET'S DO THE SAME THING WITH THE 2509 01:40:58,989 --> 01:40:59,356 EXPOSOME. 2510 01:40:59,356 --> 01:41:00,724 LET'S HAVE THAT BOLD VISION. 2511 01:41:00,724 --> 01:41:03,093 WE HAVE TO DEVELOP A FRAMEWORK 2512 01:41:03,093 --> 01:41:05,428 FOR LOOKING AT THE TOTALITY OF 2513 01:41:05,428 --> 01:41:08,064 EXPOSURES AND UNDERSTANDING THE 2514 01:41:08,064 --> 01:41:09,366 BIOLOGICAL CONSEQUENCES OF THESE 2515 01:41:09,366 --> 01:41:10,800 EXPOSURES, AND WE HAVE TO FIGURE 2516 01:41:10,800 --> 01:41:12,135 OUT WHAT ARE THE TECHNOLOGIES 2517 01:41:12,135 --> 01:41:14,204 THAT WE NEED TO ACTUALLY MAKE 2518 01:41:14,204 --> 01:41:15,305 SOME OF THAT HAPPEN. 2519 01:41:15,305 --> 01:41:17,807 SO LET'S GO TO THE NEXT SLIDE 2520 01:41:17,807 --> 01:41:18,008 HERE. 2521 01:41:18,008 --> 01:41:20,677 SO ONE OF THE CRITICAL THINGS 2522 01:41:20,677 --> 01:41:23,713 THAT WE NEED TO DO, ACTUALLY SO 2523 01:41:23,713 --> 01:41:26,750 MUCH FOLLOWED FROM A SERIES OF 2524 01:41:26,750 --> 01:41:28,184 WORKSHOPS THAT NIEHS TOGETHER 2525 01:41:28,184 --> 01:41:29,619 WITH OTHER INSTITUTES AND 2526 01:41:29,619 --> 01:41:33,323 CENTERS SPONSORED DURING THE 2527 01:41:33,323 --> 01:41:35,859 SUMMER OF 2022, IS WE WANTED TO 2528 01:41:35,859 --> 01:41:40,563 KNOW HOW DO YOU OPERATIONALIZE 2529 01:41:40,563 --> 01:41:41,031 EXPOSOMICS? 2530 01:41:41,031 --> 01:41:44,901 SO WHAT WE'RE DOING NOW IS WE 2531 01:41:44,901 --> 01:41:47,103 ARE PROMOTING THIS CONCEPT OF 2532 01:41:47,103 --> 01:41:49,205 DEVELOPING THE GLOBAL EXPOSOME 2533 01:41:49,205 --> 01:41:50,707 RESEARCH COORDINATION TO 2534 01:41:50,707 --> 01:41:51,174 ACCELERATE PRECISION 2535 01:41:51,174 --> 01:41:51,875 ENVIRONMENTAL HEALTH. 2536 01:41:51,875 --> 01:41:54,244 I'LL TALK ABOUT THAT IN A COUPLE 2537 01:41:54,244 --> 01:41:54,477 MINUTES. 2538 01:41:54,477 --> 01:41:58,515 SO, THE OVERALL GOAL IS TO 2539 01:41:58,515 --> 01:42:00,583 CREATE THE CENTER TO DEVELOP A 2540 01:42:00,583 --> 01:42:02,352 COMMONLY AGREED UPON FRAMEWORK 2541 01:42:02,352 --> 01:42:03,987 FOR EXPOSOMICS, PROMOTE BEST 2542 01:42:03,987 --> 01:42:05,422 PRACTICES AND DATA COLLECTION 2543 01:42:05,422 --> 01:42:08,792 AND SHARING, WHAT DATA DO WE 2544 01:42:08,792 --> 01:42:10,560 COLLECT IF WE'RE DOING EXPOSOMIC 2545 01:42:10,560 --> 01:42:12,529 EXPERIMENT AND TO BUILD A GLOBAL 2546 01:42:12,529 --> 01:42:15,365 RESEARCH COMMUNITY OF DIVERSITY 2547 01:42:15,365 --> 01:42:17,000 AND INCLUSION TO FOSTER NATIONAL 2548 01:42:17,000 --> 01:42:19,369 AND INTERNATIONAL COLLABORATION. 2549 01:42:19,369 --> 01:42:21,404 THERE ARE THREE DIFFERENT AREAS 2550 01:42:21,404 --> 01:42:24,240 OF FOCUS FOR THIS CENTER, AND I 2551 01:42:24,240 --> 01:42:25,775 WANT TO ALSO EMPHASIZE THE 2552 01:42:25,775 --> 01:42:27,877 IMPORTANCE OF BUILDING THAT 2553 01:42:27,877 --> 01:42:28,945 GLOBAL EXPOSOME RESEARCH 2554 01:42:28,945 --> 01:42:29,212 COMMUNITY. 2555 01:42:29,212 --> 01:42:31,815 SO THERE'S A LOT OF WORK THAT'S 2556 01:42:31,815 --> 01:42:32,449 HAPPENING IN EXPOSOMICS ACROSS, 2557 01:42:32,449 --> 01:42:34,417 FOR EXAMPLE, MANY OF THE 2558 01:42:34,417 --> 01:42:36,086 COUNTRIES ACROSS THE EUROPEAN 2559 01:42:36,086 --> 01:42:42,092 UNION, AND WHAT WE WANT TO DO IS 2560 01:42:42,092 --> 01:42:43,259 DEVELOP THIS PARTNERSHIP IN 2561 01:42:43,259 --> 01:42:45,161 THESE COUNTRIES, ONE OF THE 2562 01:42:45,161 --> 01:42:45,929 FAILURES OF THE GENOME PROJECT 2563 01:42:45,929 --> 01:42:48,898 EARLY ON IS THAT YOU HAD 2564 01:42:48,898 --> 01:42:51,201 DIFFERENT COUNTRIES THAT 2565 01:42:51,201 --> 01:42:52,969 EMBRACED THE GENOME PRINCIPLES 2566 01:42:52,969 --> 01:42:54,270 BUT THEY WERE COMPETING WITH 2567 01:42:54,270 --> 01:42:58,108 EACH OTHER. 2568 01:42:58,108 --> 01:42:59,409 SO FRANCIS COLLINS BROUGHT 2569 01:42:59,409 --> 01:43:04,147 TOGETHER THE PUBLIC COMMUNITY 2570 01:43:04,147 --> 01:43:05,749 GETTING PEOPLE WORKING TOGETHER 2571 01:43:05,749 --> 01:43:09,986 TO ACHIEVE THE END PRODUCT. 2572 01:43:09,986 --> 01:43:12,422 LET'S DO THE SAME THING WITH 2573 01:43:12,422 --> 01:43:13,056 EXPOSOMICS. 2574 01:43:13,056 --> 01:43:19,996 LET'S GO TO THE NEXT SLIDE. 2575 01:43:19,996 --> 01:43:21,097 OOPS, SORRY. 2576 01:43:21,097 --> 01:43:22,399 A SLIDE MISSING. 2577 01:43:22,399 --> 01:43:23,833 WHAT WE'VE DONE -- GO BACK TO 2578 01:43:23,833 --> 01:43:26,136 THE PREVIOUS SLIDE. 2579 01:43:26,136 --> 01:43:27,771 WE'VE NOW ACTUALLY PROMOTED 2580 01:43:27,771 --> 01:43:31,207 THE -- WE HAVE A NOFO ON THE 2581 01:43:31,207 --> 01:43:31,708 STREETS. 2582 01:43:31,708 --> 01:43:33,810 THERE ARE APPLICATIONS THAT WE 2583 01:43:33,810 --> 01:43:38,281 RECEIVED TO CREATE ONE CENTER 2584 01:43:38,281 --> 01:43:39,115 THAT'S DEDICATED TO THE RESEARCH 2585 01:43:39,115 --> 01:43:40,383 STRATEGIES ON THIS SLIDE. 2586 01:43:40,383 --> 01:43:43,420 WE HOPE TO HAVE THIS FUNDED BY 2587 01:43:43,420 --> 01:43:44,654 EARLY SUMMER. 2588 01:43:44,654 --> 01:43:50,994 AND THAT ONE CENTER IS NOT TO DO 2589 01:43:50,994 --> 01:43:51,961 EXPOSOMMICS EXPERIMENTS BUT 2590 01:43:51,961 --> 01:43:56,866 REACH OUT TO GLOBAL COMMUNITY, 2591 01:43:56,866 --> 01:43:58,701 INVESTIGATORS AT DCR, PEOPLE IN 2592 01:43:58,701 --> 01:44:00,670 YOUR COMMUNITY, DEVELOP STRATEGY 2593 01:44:00,670 --> 01:44:02,539 TO OPERATIONALIZE EXPOSOMICS. 2594 01:44:02,539 --> 01:44:03,840 ONCE WE HAVE OPERATIONAL 2595 01:44:03,840 --> 01:44:07,010 FRAMEWORK WE CAN GO FORWARD AND 2596 01:44:07,010 --> 01:44:08,211 START COLLECTING THE DATA. 2597 01:44:08,211 --> 01:44:08,878 NEXT SLIDE. 2598 01:44:08,878 --> 01:44:11,848 IN THE INTEREST OF TIME, I'M 2599 01:44:11,848 --> 01:44:14,117 GOING TO MOVE ON HERE. 2600 01:44:14,117 --> 01:44:19,255 SO WE'RE FOCUSED ON EXPOSOMICS, 2601 01:44:19,255 --> 01:44:20,457 OPERATIONALIZING EXPOSOMICS. 2602 01:44:20,457 --> 01:44:21,658 ANOTHER AREA I'M INTERESTED IN 2603 01:44:21,658 --> 01:44:27,263 IS THIS CONCEPT OF PRECISION 2604 01:44:27,263 --> 01:44:31,634 ALMOST HEALTH, ADDRESSING 2605 01:44:31,634 --> 01:44:32,569 INDIVIDUAL VARIABILITY. 2606 01:44:32,569 --> 01:44:34,804 DIFFERENT PEOPLE RESPOND TO THE 2607 01:44:34,804 --> 01:44:35,405 ENVIRONMENT IN DIFFERENT WAYS. 2608 01:44:35,405 --> 01:44:40,009 AND SO THE WAY WE PRACTICE 2609 01:44:40,009 --> 01:44:41,244 ENVIRONMENTAL HEALTH SCIENCES 2610 01:44:41,244 --> 01:44:43,913 NOW IS IT'S PRETTY MUCH USING 2611 01:44:43,913 --> 01:44:44,781 STATISTICAL AVERAGES. 2612 01:44:44,781 --> 01:44:47,083 WELL, WE CAN DO BETTER THAN 2613 01:44:47,083 --> 01:44:47,283 THAT. 2614 01:44:47,283 --> 01:44:49,486 IN FACT, THIS WHOLE PROGRAM OF 2615 01:44:49,486 --> 01:44:52,055 PRE-VISION ENVIRONMENTAL HEALTH 2616 01:44:52,055 --> 01:44:53,223 COMPLEMENTS THE PRECISION 2617 01:44:53,223 --> 01:44:55,758 MEDICINE INITIATIVE, WHICH YOU 2618 01:44:55,758 --> 01:44:58,528 KNOW IS ABOUT SEQUENCING GENOME, 2619 01:44:58,528 --> 01:44:59,262 BETTER UNDERSTANDING SEQUENCE 2620 01:44:59,262 --> 01:45:03,900 VARIATIONS IN GENES WE INHERIT 2621 01:45:03,900 --> 01:45:06,736 FROM OUR PARENTS CORRELATED WITH 2622 01:45:06,736 --> 01:45:07,437 DISEASE OUTCOMES. 2623 01:45:07,437 --> 01:45:08,471 WE THINK THAT'S GREAT. 2624 01:45:08,471 --> 01:45:10,874 WE WANT TO CONTINUE TO PROMOTE 2625 01:45:10,874 --> 01:45:13,076 THE GENETICS AND GENOMICS, BUT 2626 01:45:13,076 --> 01:45:15,178 THERE'S ALSO THE ENVIRONMENTAL 2627 01:45:15,178 --> 01:45:16,246 VARIABLE HERE, ENVIRONMENT CAN 2628 01:45:16,246 --> 01:45:18,314 MAKE YOU SICK OR ENVIRONMENT CAN 2629 01:45:18,314 --> 01:45:21,417 KEEP YOU HEALTHY. 2630 01:45:21,417 --> 01:45:24,721 SO, BY PROMOTING THIS PEH 2631 01:45:24,721 --> 01:45:27,557 PROGRAM IT'S ABOUT STUDYING GENE 2632 01:45:27,557 --> 01:45:30,827 BY ENVIRONMENT EFFECTS 2633 01:45:30,827 --> 01:45:34,330 ASSOCIATED WITH THE TOTALITY OF 2634 01:45:34,330 --> 01:45:37,400 MEDICINE, TOTALITY OF HUMAN 2635 01:45:37,400 --> 01:45:39,168 EXPOSURES. 2636 01:45:39,168 --> 01:45:42,071 THE GOAL IS TO INTEGRATE 2637 01:45:42,071 --> 01:45:42,772 GENETICS, EPIGENETICS, OMICS 2638 01:45:42,772 --> 01:45:43,006 DATA. 2639 01:45:43,006 --> 01:45:45,542 SO MANY OF OUR GRANTEES 2640 01:45:45,542 --> 01:45:48,678 PROMOTING THIS CONCEPT REFER TO 2641 01:45:48,678 --> 01:45:57,687 THIS PEH IS ABOUT G x E X D. 2642 01:45:57,687 --> 01:46:01,224 ONE CHALLENGE IN THE 2643 01:46:01,224 --> 01:46:02,191 ENVIRONMENTAL HEALTH SCIENCES 2644 01:46:02,191 --> 01:46:06,996 BIOMEDICAL COMMUNITY IS IN MANY 2645 01:46:06,996 --> 01:46:09,065 OF THE GENETIC PREDISPOSITIONS 2646 01:46:09,065 --> 01:46:13,236 TO THE PHENOTYPES YOU'RE 2647 01:46:13,236 --> 01:46:18,041 INTERESTED IN, IN DCR, THAT MAY 2648 01:46:18,041 --> 01:46:19,442 BE ASSOCIATED BY GENETIC 2649 01:46:19,442 --> 01:46:20,977 EXPOSURES ARE NOT CAUSED BY 2650 01:46:20,977 --> 01:46:22,278 SINGLE GENE VARIANTS. 2651 01:46:22,278 --> 01:46:25,682 THEY FALL IN THE CATEGORY OF 2652 01:46:25,682 --> 01:46:26,783 COMPLEX TRAITS WHICH MAY MEAN 2653 01:46:26,783 --> 01:46:29,752 THERE ARE TENS OR HUNDREDS OF 2654 01:46:29,752 --> 01:46:34,123 GENES WITH SEQUENCE VARIATIONS 2655 01:46:34,123 --> 01:46:36,759 THAT ALL COLLECTIVELY 2656 01:46:36,759 --> 01:46:38,695 COLLABORATE TO TRIGGER A GENETIC 2657 01:46:38,695 --> 01:46:46,803 RESPONSE TO A GIVEN EXPOSURE OR 2658 01:46:46,803 --> 01:46:48,771 TO PREDISPOSITION TO COMMON 2659 01:46:48,771 --> 01:46:49,005 DISEASE. 2660 01:46:49,005 --> 01:46:49,939 THE COMMUNITY RECOGNIZE THIS, IF 2661 01:46:49,939 --> 01:46:53,409 WE WANT TO BEGIN TO UNDERSTAND 2662 01:46:53,409 --> 01:46:54,611 INDIVIDUAL GENES AND VARIANTS IN 2663 01:46:54,611 --> 01:46:57,814 GENES, WE NEED TO BE WORKING 2664 01:46:57,814 --> 01:46:58,648 COLLABORATIVELY TOGETHER SO WE 2665 01:46:58,648 --> 01:46:59,983 HAVE THE "ALL OF US" PROGRAM 2666 01:46:59,983 --> 01:47:02,051 WHICH I'LL TALK ABOUT IN A 2667 01:47:02,051 --> 01:47:05,355 SECOND, AT THE NIH, THERE ARE 2668 01:47:05,355 --> 01:47:07,557 LARGE COHORTS IN SEVERAL 2669 01:47:07,557 --> 01:47:09,292 COUNTRIES ACROSS THE GLOBE. 2670 01:47:09,292 --> 01:47:10,827 SO WHY DON'T WE WORK TOGETHER, 2671 01:47:10,827 --> 01:47:14,230 WHY DON'T WE COLLECT THE DATA IN 2672 01:47:14,230 --> 01:47:16,833 A WAY THAT'S INTEGRATABLE SO WE 2673 01:47:16,833 --> 01:47:19,235 CAN, AGAIN, INTEGRATE ACROSS 2674 01:47:19,235 --> 01:47:20,803 DIFFERENT COHORTS AND THEN 2675 01:47:20,803 --> 01:47:22,972 ULTIMATELY HAVE THE ACCESS TO 2676 01:47:22,972 --> 01:47:26,142 TENS OF MILLIONS OF INDIVIDUALS 2677 01:47:26,142 --> 01:47:28,444 AND GENOMES SEQUENCED TO ALLOW 2678 01:47:28,444 --> 01:47:30,046 US TO ULTIMATELY PIECE TOGETHER 2679 01:47:30,046 --> 01:47:32,315 AND UNDERSTAND COMPLEX TRAITS 2680 01:47:32,315 --> 01:47:33,182 ASSOCIATED WITH COMMON DISEASE 2681 01:47:33,182 --> 01:47:35,251 AND WHAT WE'RE DOING IS WORKING 2682 01:47:35,251 --> 01:47:39,322 TOGETHER WITH THESE COHORTS TO 2683 01:47:39,322 --> 01:47:41,190 INTEGRATE EXPOSOMIC VARIABLES IN 2684 01:47:41,190 --> 01:47:42,025 COLLECTING OF DATA. 2685 01:47:42,025 --> 01:47:43,793 SO NEXT SLIDE. 2686 01:47:43,793 --> 01:47:45,662 A TANGIBLE STEP IN THIS 2687 01:47:45,662 --> 01:47:46,663 DIRECTION IS TO WORK TOGETHER 2688 01:47:46,663 --> 01:47:48,297 WITH OUR "ALL OF US" PROGRAM. 2689 01:47:48,297 --> 01:47:51,034 REMIND ALL OF YOU THIS IS THE 2690 01:47:51,034 --> 01:47:53,002 MILLION-PERSON COHORT SPONSORED 2691 01:47:53,002 --> 01:47:55,204 BY THE NIH, ALL ABOUT 2692 01:47:55,204 --> 01:47:56,606 INDIVIDUALIZED PREVENTION, 2693 01:47:56,606 --> 01:47:58,374 TREATMENT, AND CARE FOR 2694 01:47:58,374 --> 01:47:59,442 INDIVIDUALS. 2695 01:47:59,442 --> 01:48:00,209 AND JOSH DENNY AND GEOFF 2696 01:48:00,209 --> 01:48:03,079 GINSBERG, JOSH IS THE CEO, GEOFF 2697 01:48:03,079 --> 01:48:05,348 IS THE CHIEF MEDICAL AND 2698 01:48:05,348 --> 01:48:06,449 SCIENTIFIC OFFICER, THEY FULLY 2699 01:48:06,449 --> 01:48:08,885 UNDERSTAND THAT IF YOU REALLY 2700 01:48:08,885 --> 01:48:09,986 WANT TO IMPLEMENT PRECISION 2701 01:48:09,986 --> 01:48:11,621 MEDICINE YOU HAVE TO INTEGRATE 2702 01:48:11,621 --> 01:48:12,488 THE ENVIRONMENT INTO THE 2703 01:48:12,488 --> 01:48:12,989 EQUATION. 2704 01:48:12,989 --> 01:48:15,992 SO THEY ARE WORKING WITH US. 2705 01:48:15,992 --> 01:48:16,426 NEXT SLIDE. 2706 01:48:16,426 --> 01:48:19,162 SO THE GOOD NEWS IS THAT THEY 2707 01:48:19,162 --> 01:48:21,898 ARE CONTINUING TO COLLECT 2708 01:48:21,898 --> 01:48:24,801 GENOMICS AND WEARABLE, 2709 01:48:24,801 --> 01:48:26,803 BIOSPECIMENS, INTEGRATING WITH 2710 01:48:26,803 --> 01:48:27,503 ELECTRONIC HEALTH RECORDS, 2711 01:48:27,503 --> 01:48:28,571 ADDING ENVIRONMENTAL DATA, PIECE 2712 01:48:28,571 --> 01:48:30,540 OF THE PIE, VERY IMPORTANT 2713 01:48:30,540 --> 01:48:32,608 ELEMENT THAT CAN INFLUENCE HUMAN 2714 01:48:32,608 --> 01:48:33,276 HEALTH THROUGH ENVIRONMENTAL 2715 01:48:33,276 --> 01:48:35,912 EXPOSURES IN THE CONTEXT OF THIS 2716 01:48:35,912 --> 01:48:37,246 EXPOSOMICS FRAMEWORK. 2717 01:48:37,246 --> 01:48:39,482 WE'RE WORKING WITH THEM. 2718 01:48:39,482 --> 01:48:40,483 NEXT SLIDE. 2719 01:48:40,483 --> 01:48:43,252 SO TANGIBLE STEP FORWARD IS, 2720 01:48:43,252 --> 01:48:46,723 WELL, WHAT DO WE DO IN THE 2721 01:48:46,723 --> 01:48:47,857 CONTEXT OF EXPOSOMIC FRAMEWORK, 2722 01:48:47,857 --> 01:48:49,125 WHERE COULD WE START? 2723 01:48:49,125 --> 01:48:52,061 WE DECIDED THAT A GREAT PLACE TO 2724 01:48:52,061 --> 01:48:55,498 START WOULD BE TO ACTUALLY PUT 2725 01:48:55,498 --> 01:48:57,333 INTO THE RECORDS FOR EACH 2726 01:48:57,333 --> 01:48:59,001 MILLION PATIENTS OR INDIVIDUALS 2727 01:48:59,001 --> 01:49:00,937 WITHIN THAT COHORT WHERE DO YOU 2728 01:49:00,937 --> 01:49:02,171 LIVE, WHERE HAVE YOU LIVED, 2729 01:49:02,171 --> 01:49:04,373 WHERE DO YOU WORK AND WHERE HAVE 2730 01:49:04,373 --> 01:49:05,908 YOU WORKED? 2731 01:49:05,908 --> 01:49:07,643 YOU KNOW GIS COORDINATION, YOU 2732 01:49:07,643 --> 01:49:12,348 CAN CUP THAT WILL TO VERY 2733 01:49:12,348 --> 01:49:13,216 POWERFUL GEOSPATIAL DATABASES 2734 01:49:13,216 --> 01:49:15,084 AND LEARN ABOUT, SAY, AN 2735 01:49:15,084 --> 01:49:16,185 INDIVIDUAL'S EXPOSURE TO AIR 2736 01:49:16,185 --> 01:49:18,054 POLLUTION OR OTHER ENVIRONMENTAL 2737 01:49:18,054 --> 01:49:18,421 TOXICANTS. 2738 01:49:18,421 --> 01:49:20,890 SO THAT'S THE PHASE 1 AND PHASE 2739 01:49:20,890 --> 01:49:21,157 2. 2740 01:49:21,157 --> 01:49:24,627 GET THE ADDRESS, GET SOME ZIP 2741 01:49:24,627 --> 01:49:26,496 CODES, GET GEOSPATIAL MARKERS IN 2742 01:49:26,496 --> 01:49:27,797 FOR THESE INDIVIDUALS, PHASE 2 2743 01:49:27,797 --> 01:49:32,835 IS TO DEVELOP TOOLS TO INTEGRATE 2744 01:49:32,835 --> 01:49:34,470 THE GEOSPATIAL MARKERS INTO 2745 01:49:34,470 --> 01:49:34,904 BETTER UNDERSTANDING 2746 01:49:34,904 --> 01:49:35,738 ENVIRONMENTAL EXPOSURES. 2747 01:49:35,738 --> 01:49:38,241 THERE'S ALSO A PHASE 3 THAT GOES 2748 01:49:38,241 --> 01:49:39,075 WAY BEYOND JUST GEOSPATIAL. 2749 01:49:39,075 --> 01:49:40,743 I DON'T HAVE TIME TO GO THROUGH 2750 01:49:40,743 --> 01:49:42,378 DETAILS BUT WE HAVE A PILOT 2751 01:49:42,378 --> 01:49:44,781 PROJECT WHERE WE CAN BEGIN TO 2752 01:49:44,781 --> 01:49:46,749 INTEGRATE IN MORE DETAIL THE 2753 01:49:46,749 --> 01:49:48,518 ELEMENTS OF THE ENVIRONMENTAL 2754 01:49:48,518 --> 01:49:50,219 EXPOSURES AS RELATES TO 2755 01:49:50,219 --> 01:49:53,122 DEVELOPMENT OF TYPE 2 DIABETES. 2756 01:49:53,122 --> 01:49:53,689 NEXT SLIDE. 2757 01:49:53,689 --> 01:49:56,025 SO I'M GOING TO ACTUALLY JUST 2758 01:49:56,025 --> 01:49:58,461 LOOKING AT THE CLOCK HERE ASK 2759 01:49:58,461 --> 01:50:08,871 YOU TO SKIP TO SLIDE 17. 2760 01:50:09,238 --> 01:50:11,774 WHAT DOES THIS MEAN, THE 2761 01:50:11,774 --> 01:50:15,645 ENVIRONMENTAL EXPOSURE, 2762 01:50:15,645 --> 01:50:16,245 EXPOSOME, PRECISION 2763 01:50:16,245 --> 01:50:16,879 ENVIRONMENTAL HEALTH, RELATIVE 2764 01:50:16,879 --> 01:50:18,147 TO SCIENCE AND HEALTH THAT 2765 01:50:18,147 --> 01:50:19,782 YOU'RE INTERESTED IN? 2766 01:50:19,782 --> 01:50:20,449 NEXT SLIDE. 2767 01:50:20,449 --> 01:50:22,618 I DON'T HAVE TIME TO GO INTO A 2768 01:50:22,618 --> 01:50:24,153 LOT OF DETAILS BUT THERE'S SOME 2769 01:50:24,153 --> 01:50:26,222 VERY COMPELLING DATA IN THE 2770 01:50:26,222 --> 01:50:27,657 LITERATURE, THAT SEEMS TO 2771 01:50:27,657 --> 01:50:30,827 INDICATE MATERNAL SMOKING IS 2772 01:50:30,827 --> 01:50:33,029 ASSOCIATED WITH INCREASED RISK 2773 01:50:33,029 --> 01:50:35,198 OF CLEFT LIP AND PALATE, LIKELY 2774 01:50:35,198 --> 01:50:41,337 TO BE A GENE BY ENVIRONMENT, 2775 01:50:41,337 --> 01:50:50,980 SEQUENCE VARIATIONS IN GSP 1, 2776 01:50:50,980 --> 01:50:55,117 NAT 1 WITH THIS PHENOTYPE. 2777 01:50:55,117 --> 01:50:57,320 SMOKING HAS A NUMBER OF 2778 01:50:57,320 --> 01:50:58,721 ELEMENTS, PARTICULATE MATTER 2779 01:50:58,721 --> 01:51:01,157 REMINDS YOU OF SOME OF THE 2780 01:51:01,157 --> 01:51:04,794 ELEMENTS OF AIR POLLUTION, THERE 2781 01:51:04,794 --> 01:51:06,963 ARE PUBLICATIONS THAT ASSOCIATE 2782 01:51:06,963 --> 01:51:10,800 THE EXPOSURE TO PARTICULATE 2783 01:51:10,800 --> 01:51:14,971 MATTER IN AIR POLLUTION, CARBON 2784 01:51:14,971 --> 01:51:18,140 MONOXIDE, WITH INCREASED CLEFT 2785 01:51:18,140 --> 01:51:20,810 PALATE AND MATERNAL RESIDENTIAL 2786 01:51:20,810 --> 01:51:25,681 PROXIMITY TO INDUSTRIAL 2787 01:51:25,681 --> 01:51:28,784 EMISSIONS, FLUORINATED SOLVENTS 2788 01:51:28,784 --> 01:51:31,921 AND INCREASED INSURE OF CL/P. 2789 01:51:31,921 --> 01:51:33,789 DATA INDICATES YOU GOT TO PAY 2790 01:51:33,789 --> 01:51:36,525 ATTENTION TO ENVIRONMENTAL 2791 01:51:36,525 --> 01:51:37,727 EXPOSURE. 2792 01:51:37,727 --> 01:51:41,898 FINAL SLIDE HERE, THERE ARE ALSO 2793 01:51:41,898 --> 01:51:45,167 THE IMPACT OF THE ORAL 2794 01:51:45,167 --> 01:51:45,601 MICROBIOME. 2795 01:51:45,601 --> 01:51:49,205 THERE'S DATA TO SUGGEST THAT 2796 01:51:49,205 --> 01:51:51,307 THERE'S ACTUALLY THIS CHEMICAL 2797 01:51:51,307 --> 01:51:54,577 COMPOUND THAT'S SPRAYED ON 2798 01:51:54,577 --> 01:51:56,112 APPLES, ABBREVIATED AZM, SO WHEN 2799 01:51:56,112 --> 01:51:59,949 PEOPLE WENT IN AND LOOKED AT THE 2800 01:51:59,949 --> 01:52:02,018 MICROBIOME OF INDIVIDUALS LIVING 2801 01:52:02,018 --> 01:52:04,553 ON FARMS, NEAR FARMS, THEY FOUND 2802 01:52:04,553 --> 01:52:06,522 THAT THERE'S A CORRELATION 2803 01:52:06,522 --> 01:52:11,093 BETWEEN BLOOD LEVELS OF AZM AND 2804 01:52:11,093 --> 01:52:17,366 CHANGES IN KEY TAXA OF THE ORAL 2805 01:52:17,366 --> 01:52:21,203 MICROBIOME WHICH WERE SUGGESTIVE 2806 01:52:21,203 --> 01:52:23,239 OF A POTENTIAL CONNECTION 2807 01:52:23,239 --> 01:52:25,408 BETWEEN ENVIRONMENTAL EXPOSURE, 2808 01:52:25,408 --> 01:52:26,375 CHANGES IN MICROBIOME AND 2809 01:52:26,375 --> 01:52:28,744 QUALITY OF ORAL HEALTH. 2810 01:52:28,744 --> 01:52:29,111 NEXT SLIDE. 2811 01:52:29,111 --> 01:52:32,415 SO I THINK THIS IS A WAY OF 2812 01:52:32,415 --> 01:52:34,450 INTRODUCING HERE A Q&A PERIOD. 2813 01:52:34,450 --> 01:52:36,786 SO I THINK WE CAN TALK ABOUT 2814 01:52:36,786 --> 01:52:39,588 WHAT ARE SOME OF THOSE 2815 01:52:39,588 --> 01:52:43,092 ENVIRONMENTAL EXPOSURES THAT MAY 2816 01:52:43,092 --> 01:52:45,861 BE IMPACTING INDIVIDUALS, 2817 01:52:45,861 --> 01:52:48,230 IMPACTING ORAL AND CRANIOFACIAL 2818 01:52:48,230 --> 01:52:49,265 DISORDERS AND OTHER THINGS? 2819 01:52:49,265 --> 01:52:52,368 I THINK WE'RE JUST BEGINNING TO 2820 01:52:52,368 --> 01:52:53,569 UNDERSTAND WHAT SOME OF THESE 2821 01:52:53,569 --> 01:52:54,103 MAY BE. 2822 01:52:54,103 --> 01:52:55,638 I'M ALSO VERY INTERESTED IN 2823 01:52:55,638 --> 01:52:58,174 WORKING WITH YOU ON THOSE GENE 2824 01:52:58,174 --> 01:52:58,941 BY ENVIRONMENT THINGS. 2825 01:52:58,941 --> 01:53:00,910 WE DIDN'T HAVE A CHANCE TO GO 2826 01:53:00,910 --> 01:53:02,578 INTO CLIMATE CHANGE AND HEALTH, 2827 01:53:02,578 --> 01:53:04,413 IF MEMBERS OF THE COUNCIL ARE 2828 01:53:04,413 --> 01:53:06,048 INTERESTED IN SOME OTHER AREAS 2829 01:53:06,048 --> 01:53:07,383 I'D BE HAPPY TO ENTERTAIN ANY 2830 01:53:07,383 --> 01:53:07,650 QUESTIONS. 2831 01:53:07,650 --> 01:53:09,986 BUT I THINK IN THE INTEREST OF 2832 01:53:09,986 --> 01:53:11,087 TIME, RENA, I SHOULD PROBABLY 2833 01:53:11,087 --> 01:53:13,089 STOP TALKING AND LET'S OPEN UP 2834 01:53:13,089 --> 01:53:13,923 FOR Q&A. 2835 01:53:13,923 --> 01:53:14,824 >> THANK YOU, RICK. 2836 01:53:14,824 --> 01:53:17,326 THANK YOU VERY MUCH. 2837 01:53:17,326 --> 01:53:19,061 THAT WAS VERY, VERY STIMULATING, 2838 01:53:19,061 --> 01:53:21,597 REALLY EXCITING TO KNOW ABOUT 2839 01:53:21,597 --> 01:53:23,232 THE DIRECTIONS YOU'RE TAKING THE 2840 01:53:23,232 --> 01:53:24,800 INSTITUTE IN. 2841 01:53:24,800 --> 01:53:25,568 REALLY APPRECIATE YOUR 2842 01:53:25,568 --> 01:53:25,868 LEADERSHIP. 2843 01:53:25,868 --> 01:53:31,007 THERE'S SO MUCH MORE TO COME, AS 2844 01:53:31,007 --> 01:53:32,141 WE ARE BOTH EXCITED ABOUT. 2845 01:53:32,141 --> 01:53:34,410 THANK YOU VERY MUCH. 2846 01:53:34,410 --> 01:53:36,712 I'LL OPEN UP TO QUESTIONS FROM 2847 01:53:36,712 --> 01:53:37,813 OUR COUNCIL. 2848 01:53:37,813 --> 01:53:40,683 THERE'S A LARGE GROUP THAT 2849 01:53:40,683 --> 01:53:43,352 ATTENDS THROUGH VIDEOCAST, AND 2850 01:53:43,352 --> 01:53:45,021 THEY WILL HAVE QUESTIONS. 2851 01:53:45,021 --> 01:53:47,123 YOU DON'T HAVE ACCESS RIGHT NOW 2852 01:53:47,123 --> 01:53:49,458 SO I'LL DIRECT THEM TO YOU 2853 01:53:49,458 --> 01:53:49,859 LATER. 2854 01:53:49,859 --> 01:53:51,627 ANYONE ON COUNCIL OR, JENNIFER, 2855 01:53:51,627 --> 01:53:52,061 OUR STAFF? 2856 01:53:52,061 --> 01:53:53,696 >> WHY DON'T WE STOP SHOWING THE 2857 01:53:53,696 --> 01:53:57,433 SLIDES SO I CAN SEE THE 2858 01:53:57,433 --> 01:53:58,200 HOLLYWOOD SQUARES. 2859 01:53:58,200 --> 01:53:59,335 JENNIFER, YOUR HAND IS UP. 2860 01:53:59,335 --> 01:54:02,838 >> MY HAND IS UP. 2861 01:54:02,838 --> 01:54:03,572 THANK YOU. 2862 01:54:03,572 --> 01:54:08,577 THANK YOU FOR A GREAT TALK AND 2863 01:54:08,577 --> 01:54:09,912 GREAT EXPOSURE TO NIEHS. 2864 01:54:09,912 --> 01:54:13,215 ONE THING THAT WAS STRIKING TO 2865 01:54:13,215 --> 01:54:15,284 ME, AS YOU SHARED WITH US HOW 2866 01:54:15,284 --> 01:54:19,455 YOU DEFINE EXPOSOME AND THREE 2867 01:54:19,455 --> 01:54:20,523 DIFFERENT AREAS, EXTERNAL, 2868 01:54:20,523 --> 01:54:22,458 BIOLOGICAL RESPONSES, AND 2869 01:54:22,458 --> 01:54:24,794 PERSONAL EXPOSOME, ALL OF THOSE 2870 01:54:24,794 --> 01:54:25,828 BIOLOGICAL RESPONSES CAN 2871 01:54:25,828 --> 01:54:29,932 ACTUALLY BE MEASURED IN THE 2872 01:54:29,932 --> 01:54:30,132 MOUTH. 2873 01:54:30,132 --> 01:54:31,867 IN SALIVA, READILY AVAILABLE 2874 01:54:31,867 --> 01:54:35,104 FLUID, AND SEVERAL OF THE 2875 01:54:35,104 --> 01:54:37,273 PERSONAL EXPOSOME THINGS LIKE 2876 01:54:37,273 --> 01:54:38,941 DIET, TOXIC CHEMICALS WHICH YOU 2877 01:54:38,941 --> 01:54:40,576 JUST SHOWED US, SMOKING, CAN 2878 01:54:40,576 --> 01:54:46,715 ALSO BE MEASURED THERE. 2879 01:54:46,715 --> 01:54:48,384 SO, AS WE PLAN THESE NATIONAL 2880 01:54:48,384 --> 01:54:50,519 STUDIES LIKE THE LAST ONE I 2881 01:54:50,519 --> 01:54:53,355 TALKED ABOUT, WHERE WE'RE GOING 2882 01:54:53,355 --> 01:54:56,192 TO BE TARGETING -- "ALL OF US" 2883 01:54:56,192 --> 01:54:57,860 IS GREAT, SOME SALIVA IS 2884 01:54:57,860 --> 01:54:59,161 COLLECTED THERE, GREAT, BUT 2885 01:54:59,161 --> 01:55:02,364 THESE NATIONAL STUDIES WHERE 2886 01:55:02,364 --> 01:55:05,167 WE'RE TARGETING VULNERABLE 2887 01:55:05,167 --> 01:55:07,169 POPULATIONS, RURAL POPULATIONS, 2888 01:55:07,169 --> 01:55:10,906 BUREAU OF PRISONS, INDIAN HEALTH 2889 01:55:10,906 --> 01:55:12,975 SERVICE, V.A., AND LONGITUDINAL 2890 01:55:12,975 --> 01:55:14,343 COMPONENT THERE, I THINK THERE 2891 01:55:14,343 --> 01:55:17,613 MAY BE AN OPPORTUNITY TO LOOK AT 2892 01:55:17,613 --> 01:55:21,183 GEOSPATIAL EXPOSURES WITHIN 2893 01:55:21,183 --> 01:55:23,619 THOSE TARGETED POPULATIONS SO 2894 01:55:23,619 --> 01:55:26,355 WANTED TO SEE WHAT YOU THINK 2895 01:55:26,355 --> 01:55:28,891 ABOUT THAT BECAUSE FLUID COULD 2896 01:55:28,891 --> 01:55:29,558 BE HELPFUL. 2897 01:55:29,558 --> 01:55:30,159 >> SPOT ON. 2898 01:55:30,159 --> 01:55:32,795 I THINK THAT IS REALLY A 2899 01:55:32,795 --> 01:55:33,462 TERRIFIC SUGGESTION. 2900 01:55:33,462 --> 01:55:35,364 AND SO WE NEED TO TALK MORE 2901 01:55:35,364 --> 01:55:36,799 ABOUT THIS. 2902 01:55:36,799 --> 01:55:39,068 IT'S A READILY AVAILABLE FLUID. 2903 01:55:39,068 --> 01:55:39,301 >> YEP. 2904 01:55:39,301 --> 01:55:40,035 >> OKAY. 2905 01:55:40,035 --> 01:55:43,139 AND WE NEED TO BE PAYING 2906 01:55:43,139 --> 01:55:43,739 ATTENTION AND THINKING ABOUT 2907 01:55:43,739 --> 01:55:45,541 SALIVA AS MORE THAN JUST A 2908 01:55:45,541 --> 01:55:48,277 SOURCE OF MATERIAL THAT YOU CAN 2909 01:55:48,277 --> 01:55:52,548 EXTRACT DNA TO DO GENOME 2910 01:55:52,548 --> 01:55:52,848 SEQUENCING. 2911 01:55:52,848 --> 01:55:53,849 GENOME SEQUENCING IS USEFUL BUT 2912 01:55:53,849 --> 01:55:58,521 LOOKING AS A WAY OF EVALUATING 2913 01:55:58,521 --> 01:55:59,989 THE MICROBIOME, THE MICROBIOME 2914 01:55:59,989 --> 01:56:01,724 IS AN INTEGRAL PART OF THE 2915 01:56:01,724 --> 01:56:02,491 EXPOSOMIC FRAMEWORK. 2916 01:56:02,491 --> 01:56:04,260 IT HAS TO BE. 2917 01:56:04,260 --> 01:56:07,496 AND NOW THAT WE HAVE THE 2918 01:56:07,496 --> 01:56:09,064 POWERFUL TOOLS, GENETICKICS AND 2919 01:56:09,064 --> 01:56:16,505 GENOMICS THAT ALLOW US TO MORE 2920 01:56:16,505 --> 01:56:18,174 THOROUGHLY EVALUATE MICROBIOME, 2921 01:56:18,174 --> 01:56:20,142 I'M BLOWN AWAY BY HOW IMPORTANT 2922 01:56:20,142 --> 01:56:21,677 THE MICROBIOME IS. 2923 01:56:21,677 --> 01:56:25,614 IN FACT, I OFTEN WONDER ABOUT MY 2924 01:56:25,614 --> 01:56:27,716 OWN MICROBIOME AND HOW I COULD 2925 01:56:27,716 --> 01:56:28,817 BE IMPROVING MY OWN MICROBIOME 2926 01:56:28,817 --> 01:56:30,686 TO IMPROVE MY ORAL HEALTH. 2927 01:56:30,686 --> 01:56:31,687 IT'S ABSOLUTELY SOMETHING WE 2928 01:56:31,687 --> 01:56:34,723 NEED TO BE CONSIDERING. 2929 01:56:34,723 --> 01:56:37,793 IT'S READILY AVAILABLE SOURCE OF 2930 01:56:37,793 --> 01:56:39,695 BIOLOGICAL FLUID. 2931 01:56:39,695 --> 01:56:43,165 >> YOU GOT ORAL METABOLOME, ORAL 2932 01:56:43,165 --> 01:56:47,770 INFLAMMASOME, SO ALL OF THESE 2933 01:56:47,770 --> 01:56:53,876 THINGS ARE EASILY DETECTED AS 2934 01:56:53,876 --> 01:56:54,410 WELL AS TOXIC CHEMICALS. 2935 01:56:54,410 --> 01:56:56,745 >> SO MUCH OF THE EXPOSOME IS 2936 01:56:56,745 --> 01:56:57,713 INTEGRATING -- I DIDN'T HAVE 2937 01:56:57,713 --> 01:57:00,015 TIME TO GO INTO DETAILS, 2938 01:57:00,015 --> 01:57:02,851 INTEGRATING ACROSS NOT JUST 2939 01:57:02,851 --> 01:57:05,588 COLLECTING TOXIC CHEMICALS BUT 2940 01:57:05,588 --> 01:57:07,690 FACTORS IN THE POSITIVE 2941 01:57:07,690 --> 01:57:12,595 NUTRITIONAL EFFECTS AS WELL AS 2942 01:57:12,595 --> 01:57:13,195 OTHER OMICS, TRANSCRIPTOMICS, 2943 01:57:13,195 --> 01:57:13,696 GENOMICS, METABOLOMICS. 2944 01:57:13,696 --> 01:57:22,037 >> THANK YOU. 2945 01:57:22,037 --> 01:57:23,439 DR. VISEL, LAWRENCE BERKELEY 2946 01:57:23,439 --> 01:57:25,307 LAB, LED OUR WORKING GROUP TO 2947 01:57:25,307 --> 01:57:28,143 DEVELOP DATA SCIENCE STRATEGY 2948 01:57:28,143 --> 01:57:28,577 FOR THE INSTITUTE. 2949 01:57:28,577 --> 01:57:32,848 >> YEAH, I CANNOT TURN ON MY 2950 01:57:32,848 --> 01:57:34,617 VIDEO. 2951 01:57:34,617 --> 01:57:38,087 OH, NOW IT WORKS. 2952 01:57:38,087 --> 01:57:39,188 ALL RIGHT. 2953 01:57:39,188 --> 01:57:42,791 THIS WAS A GREAT PRESENTATION. 2954 01:57:42,791 --> 01:57:45,227 I WAS IMPRESSED BY THE VISION 2955 01:57:45,227 --> 01:57:47,963 THAT YOU OUTLINED FOR MORE 2956 01:57:47,963 --> 01:57:50,132 COORDINATED EFFORTS TO COLLECT 2957 01:57:50,132 --> 01:57:50,699 ENVIRONMENTAL HEALTH DATA 2958 01:57:50,699 --> 01:57:53,435 DEGRADATION RATED WITH OTHER 2959 01:57:53,435 --> 01:57:54,169 DATA TYPES. 2960 01:57:54,169 --> 01:57:56,805 I'M COMING FROM A GENOMICS 2961 01:57:56,805 --> 01:57:59,475 BACKGROUND MYSELF, AND SO I LIKE 2962 01:57:59,475 --> 01:58:05,681 THE PARALLELS WHERE YOU -- THAT 2963 01:58:05,681 --> 01:58:07,116 YOU'RE DOING AND HUMAN GENOME 2964 01:58:07,116 --> 01:58:07,516 PROJECT. 2965 01:58:07,516 --> 01:58:11,520 NOW, THINKING ABOUT IT ONE OF 2966 01:58:11,520 --> 01:58:13,555 THE BIG CONCEPTUAL LEGACIES OF 2967 01:58:13,555 --> 01:58:16,558 THE HUMAN GENOME PROJECT IS THE 2968 01:58:16,558 --> 01:58:19,528 IDEA OF SHARING DATA AND SHARING 2969 01:58:19,528 --> 01:58:21,930 DATA EARLY, PRE-PUBLICATION, 2970 01:58:21,930 --> 01:58:23,999 MAKING IT WIDELY ACCESSIBLE, 2971 01:58:23,999 --> 01:58:25,934 HUMAN GENOME WAS SEQUENCED, 2972 01:58:25,934 --> 01:58:26,802 ESSENTIALLY MADE DATE AVAILABLE 2973 01:58:26,802 --> 01:58:32,308 AS IT CAME OFF THE SEQUENCERS, 2974 01:58:32,308 --> 01:58:36,078 STILL TODAY THIS TRADITION LIVES 2975 01:58:36,078 --> 01:58:37,846 ON IN THE GENOMICS COMMUNITY, 2976 01:58:37,846 --> 01:58:39,915 MOST OTHER COMMUNITIES THE DATA 2977 01:58:39,915 --> 01:58:42,318 AND INCLUDING RAW DATA GETS 2978 01:58:42,318 --> 01:58:42,785 SHARED. 2979 01:58:42,785 --> 01:58:44,720 MY QUESTION IS, TO WHAT EXTENT 2980 01:58:44,720 --> 01:58:47,022 DO YOU THINK IT WOULD BE 2981 01:58:47,022 --> 01:58:49,358 FEASIBLE TO MIRROR THAT ASPECT 2982 01:58:49,358 --> 01:58:52,795 OF THE GENOME PROJECT IN MAKING 2983 01:58:52,795 --> 01:58:54,563 ENVIRONMENTAL HEALTH DATA WIDELY 2984 01:58:54,563 --> 01:58:56,065 AVAILABLE, EARLY, AVAILABLE FOR 2985 01:58:56,065 --> 01:59:00,769 REUSE BY OTHERS AND SO ON? 2986 01:59:00,769 --> 01:59:02,905 >> WELL, DR. VISEL, FIRST OF ALL 2987 01:59:02,905 --> 01:59:05,941 I SPENT PART OF MY CAREER AT THE 2988 01:59:05,941 --> 01:59:08,844 OAK RIDGE NATIONAL LABORATORY, A 2989 01:59:08,844 --> 01:59:10,913 LOT OF INTERACTION WITH YOUR 2990 01:59:10,913 --> 01:59:13,148 COLLEAGUES, STILL CALLED THE 2991 01:59:13,148 --> 01:59:13,315 JJI? 2992 01:59:13,315 --> 01:59:13,549 >> YES. 2993 01:59:13,549 --> 01:59:15,684 >> LOTS OF COORDINATION WITH 2994 01:59:15,684 --> 01:59:16,852 EDDIE RUBIN AND OTHERS. 2995 01:59:16,852 --> 01:59:18,387 ANYWAY, TO ANSWER YOUR QUESTION, 2996 01:59:18,387 --> 01:59:18,821 ABSOLUTELY. 2997 01:59:18,821 --> 01:59:20,356 THAT'S WHAT WE NEED TO BE DOING. 2998 01:59:20,356 --> 01:59:23,392 WE NEED TO BE DEVELOPING THE 2999 01:59:23,392 --> 01:59:24,760 DATA SHARING FRAMEWORK. 3000 01:59:24,760 --> 01:59:29,331 IN FACT IN MANY WAYS, THE 3001 01:59:29,331 --> 01:59:30,766 EXPOSOME IS ACTUALLY THE 3002 01:59:30,766 --> 01:59:32,067 INTEGRATED DATA NETWORK, GLOBAL 3003 01:59:32,067 --> 01:59:32,735 DATA NETWORK. 3004 01:59:32,735 --> 01:59:35,471 SO EVEN IF YOU'RE DOING ONE 3005 01:59:35,471 --> 01:59:37,172 EXPOSURE AT A TIME, IT SHOULD BE 3006 01:59:37,172 --> 01:59:38,974 A DATA NETWORK WHERE YOU CAN 3007 01:59:38,974 --> 01:59:40,809 SUBMIT YOUR DATA. 3008 01:59:40,809 --> 01:59:42,678 WE NEED COMMON DATA ELEMENTS, WE 3009 01:59:42,678 --> 01:59:44,680 NEED SIMILAR TO WHAT WE DID IN 3010 01:59:44,680 --> 01:59:46,648 THE GENOMICS COMMUNITY, IT'S NOT 3011 01:59:46,648 --> 01:59:47,249 EVERYONE DOING WHATEVER THEY 3012 01:59:47,249 --> 01:59:48,951 WANT TO DO BUT COLLECTING DATA 3013 01:59:48,951 --> 01:59:52,054 IN A WAY THAT IT CAN BE 3014 01:59:52,054 --> 01:59:53,555 SEAMLESSLY INTEGRATED INTO THESE 3015 01:59:53,555 --> 01:59:54,890 COMMON SHARED REPOSITORIES. 3016 01:59:54,890 --> 01:59:56,091 NOW, DOESN'T MEAN EVERYONE HAS 3017 01:59:56,091 --> 01:59:59,495 TO SHARE IN A SINGLE PLACE. 3018 01:59:59,495 --> 02:00:01,797 BUT HAVING THESE COMMON DATA 3019 02:00:01,797 --> 02:00:03,766 ELEMENTS AND SEAMLESS SHARING OF 3020 02:00:03,766 --> 02:00:05,734 DATA, I THINK THAT'S GOING TO BE 3021 02:00:05,734 --> 02:00:07,803 A CRITICAL ELEMENT OF 3022 02:00:07,803 --> 02:00:09,204 OPERATIONALIZING EXPOSOMICS, 3023 02:00:09,204 --> 02:00:11,306 WHAT DATA DO WE COLLECT. 3024 02:00:11,306 --> 02:00:15,778 GOING BEYOND ONE EXPOSURE AT A 3025 02:00:15,778 --> 02:00:16,278 TIME SAY WITH THE HIGH 3026 02:00:16,278 --> 02:00:18,647 RESOLUTION MASS SPEC, WHAT IS 3027 02:00:18,647 --> 02:00:21,884 THE DATA STRUCTURE THAT ALLOWS 3028 02:00:21,884 --> 02:00:22,651 FOR SEAMLESS INTEGRATION? 3029 02:00:22,651 --> 02:00:24,420 ACTUALLY PART OF MY CAREER I 3030 02:00:24,420 --> 02:00:28,223 SPEND IN THE SAN FRANCISCO BAY 3031 02:00:28,223 --> 02:00:30,192 AREA, CHIEF SCIENTIFIC OFFICER 3032 02:00:30,192 --> 02:00:32,728 AT LINKS THERAPEUTICS THAT 3033 02:00:32,728 --> 02:00:34,830 DEVELOPED FIRST GENERATION OF 3034 02:00:34,830 --> 02:00:35,964 TRANSCRIPTOMICS, RNAseq. 3035 02:00:35,964 --> 02:00:38,934 AND SO THAT'S WHY WE'RE LOOKING 3036 02:00:38,934 --> 02:00:40,903 CAN WE DEVELOP TYPES OF 3037 02:00:40,903 --> 02:00:43,439 TECHNOLOGIES THAT IN THAT CASE 3038 02:00:43,439 --> 02:00:45,307 CAPTURE TRANSCRIPTOME BUT ALSO 3039 02:00:45,307 --> 02:00:47,943 CAPTURED TRANSCRIPTOME IN A WAY 3040 02:00:47,943 --> 02:00:49,578 THAT MADE DATA READILY 3041 02:00:49,578 --> 02:00:50,112 SHAREABLE. 3042 02:00:50,112 --> 02:00:52,181 SO, I'M VERY CONSCIOUS ABOUT 3043 02:00:52,181 --> 02:00:52,381 THIS. 3044 02:00:52,381 --> 02:00:55,484 AND I'M REALLY PLEASED YOU ASKED 3045 02:00:55,484 --> 02:00:57,252 THE QUESTION, AND DEVELOPING 3046 02:00:57,252 --> 02:00:58,287 THAT INTEGRATED DATA REPOSITORY 3047 02:00:58,287 --> 02:01:02,391 IS GOING TO BE CRITICALLY 3048 02:01:02,391 --> 02:01:02,658 IMPORTANT. 3049 02:01:02,658 --> 02:01:05,694 >> RICK, AS WE LOOK AT THE 3050 02:01:05,694 --> 02:01:08,096 COLLECTIVE EFFECT OF THE 3051 02:01:08,096 --> 02:01:10,165 ENVIRONMENT ON THE GENOME, THERE 3052 02:01:10,165 --> 02:01:15,103 COULDN'T BE A BETTER TOOL, NOT 3053 02:01:15,103 --> 02:01:19,007 TOOL BUT MODEL SYSTEM THAN 3054 02:01:19,007 --> 02:01:19,475 TEETH. 3055 02:01:19,475 --> 02:01:20,876 WE'RE DENTITIONS, BABY TEETH, 3056 02:01:20,876 --> 02:01:22,177 PERMANENT TEETH, THE BABY TEETH 3057 02:01:22,177 --> 02:01:26,014 DEVELOP AS EARLY AS SIX WEEKS IN 3058 02:01:26,014 --> 02:01:26,215 UTERO. 3059 02:01:26,215 --> 02:01:27,049 >> YEP. 3060 02:01:27,049 --> 02:01:29,751 >> NOW WHY IS IT IMPORTANT WITH 3061 02:01:29,751 --> 02:01:30,819 MANY OTHER THINGS DEVELOPING, OR 3062 02:01:30,819 --> 02:01:33,489 OTHERWISE WE WOULDN'T HAVE A 3063 02:01:33,489 --> 02:01:35,891 FETUS, THE REASON IS THERE ARE 3064 02:01:35,891 --> 02:01:38,927 HARD TISSUES, ENAMEL, IS THE 3065 02:01:38,927 --> 02:01:40,963 REPOSITORY AND REPRESENTS ALL 3066 02:01:40,963 --> 02:01:43,332 INSULTS THAT OCCUR IN UTERO TO 3067 02:01:43,332 --> 02:01:48,170 THE FETUS AND THE MOTHER BECAUSE 3068 02:01:48,170 --> 02:01:49,137 OF PLACENTAL CIRCULATION. 3069 02:01:49,137 --> 02:01:51,640 YOU HAVE A BABY BORN WITH TEETH, 3070 02:01:51,640 --> 02:01:53,308 SOMETIMES PERMANENT TEETH AS 3071 02:01:53,308 --> 02:01:55,777 WELL, MOLARS DEVELOP ALSO DURING 3072 02:01:55,777 --> 02:01:58,413 PREGNANCY, AT LEAST START 3073 02:01:58,413 --> 02:02:02,050 DEVELOPING, REFLECTED BY DEFECTS 3074 02:02:02,050 --> 02:02:02,684 IN ENAMEL. 3075 02:02:02,684 --> 02:02:05,354 YOU CAN TAKE A TOOTH THAT IS 3076 02:02:05,354 --> 02:02:08,624 SHED, GOING TO BE THROWN AWAY, 3077 02:02:08,624 --> 02:02:12,060 AND ACTUALLY SECTION IT, THE 3078 02:02:12,060 --> 02:02:15,097 WHOLE TOOTH, BY MASS SPEC, 3079 02:02:15,097 --> 02:02:17,399 DISSECT LAYERS THAT YOU FEEL -- 3080 02:02:17,399 --> 02:02:19,801 IT'S A TIMELINE THING, YOU CAN 3081 02:02:19,801 --> 02:02:21,136 ALMOST PREDICT WHEN THE INSULT 3082 02:02:21,136 --> 02:02:24,072 HAPPENED BY LOOKING AT THESE 3083 02:02:24,072 --> 02:02:24,540 INCREMENTAL LINES. 3084 02:02:24,540 --> 02:02:26,708 I WILL TALK ABOUT IT WHEN I 3085 02:02:26,708 --> 02:02:29,444 VISIT CAMPUS AND WE CAN WORK 3086 02:02:29,444 --> 02:02:30,412 TOGETHER TO STIMULATE INTEREST 3087 02:02:30,412 --> 02:02:32,514 IN THE USE OF WHAT MAJOR NATURE 3088 02:02:32,514 --> 02:02:36,885 HAS GIVEN US, TRULY A BIOLOGIC 3089 02:02:36,885 --> 02:02:37,085 TOOL. 3090 02:02:37,085 --> 02:02:40,822 >> I'M GLAD YOU BROUGHT THAT UP. 3091 02:02:40,822 --> 02:02:41,790 CRITICALLY IMPORTANT. 3092 02:02:41,790 --> 02:02:46,828 HE'S ONE OF OUR GRANTEES, I KNOW 3093 02:02:46,828 --> 02:02:55,504 HIM WELL, PART OF HEARR, A DATA 3094 02:02:55,504 --> 02:02:56,371 COLLECTION CENTER. 3095 02:02:56,371 --> 02:03:00,175 BABY TEETH IS LIKE RINGS OF A 3096 02:03:00,175 --> 02:03:01,777 TREE, WITH LASERS YOU CAN 3097 02:03:01,777 --> 02:03:03,045 ESTIMATE VERY ACCURATELY WHAT 3098 02:03:03,045 --> 02:03:05,614 ARE THE LEVELS OF, SAY, EXPOSURE 3099 02:03:05,614 --> 02:03:08,317 TO LEAD OR HEAVY METALS DURING 3100 02:03:08,317 --> 02:03:11,019 THE COURSE OF PREGNANCY. 3101 02:03:11,019 --> 02:03:12,354 REALLY IMPORTANT, REALLY 3102 02:03:12,354 --> 02:03:14,723 IMPORTANT TOOL FOR EXPOSOMICS 3103 02:03:14,723 --> 02:03:14,957 SCIENCE. 3104 02:03:14,957 --> 02:03:18,160 >> SO WITH THAT, WE THANK YOU 3105 02:03:18,160 --> 02:03:19,995 FOR YOUR TIME AND YOUR 3106 02:03:19,995 --> 02:03:20,562 WILLINGNESS. 3107 02:03:20,562 --> 02:03:21,964 I KNOW YOU'RE RECOVERING FROM 3108 02:03:21,964 --> 02:03:22,497 JET LAG. 3109 02:03:22,497 --> 02:03:24,099 WE APPRECIATE THAT. 3110 02:03:24,099 --> 02:03:26,668 IT'S THE BEGINNING OF A 3111 02:03:26,668 --> 02:03:28,303 LONG-TERM COLLABORATION WITH 3112 02:03:28,303 --> 02:03:28,604 NIEHS. 3113 02:03:28,604 --> 02:03:29,004 VERY GENEROUS. 3114 02:03:29,004 --> 02:03:30,839 >> I LOOK FORWARD TO CONTINUING. 3115 02:03:30,839 --> 02:03:33,008 SEE YOU TOMORROW MORNING AT THE 3116 02:03:33,008 --> 02:03:33,508 ICD MEETING. 3117 02:03:33,508 --> 02:03:34,376 >> APPRECIATE IT. 3118 02:03:34,376 --> 02:03:35,444 THANK YOU. 3119 02:03:35,444 --> 02:03:35,677 BYE-BYE. 3120 02:03:35,677 --> 02:03:40,215 >> BYE, EVERYONE. 3121 02:03:40,215 --> 02:03:40,549 THANKS AGAIN. 3122 02:03:40,549 --> 02:03:43,452 >> THANK YOU VERY MUCH TO OUR 3123 02:03:43,452 --> 02:03:44,453 SPEAKERS. 3124 02:03:44,453 --> 02:03:49,825 NOW WE WILL MOVE TO NEW TOPIC, 3125 02:03:49,825 --> 02:03:52,961 NEXT ON THE AGENDA ONE CONCEPT 3126 02:03:52,961 --> 02:03:56,698 CLEARANCE PRESENTED BY DR. 3127 02:03:56,698 --> 02:04:00,135 PREETHI CHANDER, WE'RE REQUIRED 3128 02:04:00,135 --> 02:04:01,303 TO DOCUMENT, PRESENTING THE 3129 02:04:01,303 --> 02:04:03,372 PURPOSE, SCOPE AND OBJECTIVES IN 3130 02:04:03,372 --> 02:04:05,374 A PUBLIC FORUM. 3131 02:04:05,374 --> 02:04:07,576 SUCH AS A COUNCIL MEETING. 3132 02:04:07,576 --> 02:04:08,977 AND GIVING COUNCIL MEMBERS AND 3133 02:04:08,977 --> 02:04:12,681 THE PUBLIC THE OPPORTUNITY TO 3134 02:04:12,681 --> 02:04:12,914 COMMENT. 3135 02:04:12,914 --> 02:04:15,083 FOLLOWING THE PRESENTATION BY 3136 02:04:15,083 --> 02:04:16,618 NIDCR STAFF, DESIGNATED COUNCIL 3137 02:04:16,618 --> 02:04:18,053 MEMBERS WILL LEAD A DISCUSSION 3138 02:04:18,053 --> 02:04:19,488 FOLLOWED BY VOTE FOR APPROVAL OF 3139 02:04:19,488 --> 02:04:21,790 THE CONCEPT AS A BASIS FOR 3140 02:04:21,790 --> 02:04:25,827 DEVELOPING A FUTURE FUNDING 3141 02:04:25,827 --> 02:04:27,229 OPPORTUNITY ANNOUNCEMENT. 3142 02:04:27,229 --> 02:04:29,231 THE PROGRAM DIRECTOR OF SALIVARY 3143 02:04:29,231 --> 02:04:31,199 BIOLOGY AND IMMUNOLOGY PROGRAM 3144 02:04:31,199 --> 02:04:33,268 WILL PRESENT THE CONCEPT, 3145 02:04:33,268 --> 02:04:35,937 REISSUANCE OF NIDCR SMALL GRANT 3146 02:04:35,937 --> 02:04:39,141 PROGRAM FOR NEW INVESTIGATORS. 3147 02:04:39,141 --> 02:04:46,648 COUNCIL MEMBERS ASSIGNED TO 3148 02:04:46,648 --> 02:04:50,085 REVIEW DOCTORS NOR AND 3149 02:04:50,085 --> 02:04:50,352 KREBSBACH. 3150 02:04:50,352 --> 02:04:52,087 >> I'M PROGRAM OFFICER DIVISION 3151 02:04:52,087 --> 02:04:53,689 OF EXTRAMURAL RESEARCH. 3152 02:04:53,689 --> 02:04:55,991 I'M HERE TO SEEK COUNCIL 3153 02:04:55,991 --> 02:04:58,060 CONCURRENCE FOR REISSUANCE OF 3154 02:04:58,060 --> 02:05:01,463 THE NIDCR SMALL GRANT PROGRAM 3155 02:05:01,463 --> 02:05:04,399 FOR NEW INVESTIGATORS, R03. 3156 02:05:04,399 --> 02:05:07,269 NEXT SLIDE PLEASE. 3157 02:05:07,269 --> 02:05:10,972 THE GOAL OF THE NIDCR PROGRAM IS 3158 02:05:10,972 --> 02:05:12,340 TO PROVIDE SUPPORT FOR RESEARCH, 3159 02:05:12,340 --> 02:05:14,309 CONDUCTED BY SCIENTISTS WHO ARE 3160 02:05:14,309 --> 02:05:17,579 IN THEIR EARLY STAGES OF 3161 02:05:17,579 --> 02:05:18,980 ESTABLISHING THEIR INDEPENDENT 3162 02:05:18,980 --> 02:05:21,516 RESEARCH CAREER, IN DENTAL, 3163 02:05:21,516 --> 02:05:25,921 ORAL, CRANIOFACIAL SCIENCES. 3164 02:05:25,921 --> 02:05:26,988 THIS PROGRAM SUPPORTS 3165 02:05:26,988 --> 02:05:28,523 DEVELOPMENTAL RESEARCH PROJECTS 3166 02:05:28,523 --> 02:05:31,093 WITH INTENTION OF OBTAINING 3167 02:05:31,093 --> 02:05:36,164 PRELIMINARY DATA FOR SUBSEQUENT 3168 02:05:36,164 --> 02:05:37,365 INVESTIGATOR-INITIATED R01 3169 02:05:37,365 --> 02:05:37,666 APPLICATION. 3170 02:05:37,666 --> 02:05:40,435 IT'S EXPECTED THAT THE FOCUS ON 3171 02:05:40,435 --> 02:05:41,903 EARLY CAREER STAGE INVESTIGATORS 3172 02:05:41,903 --> 02:05:46,141 WILL HELP NIDCR BUILD A ROBUST 3173 02:05:46,141 --> 02:05:47,242 PIPELINE OF INVESTIGATORS 3174 02:05:47,242 --> 02:05:49,911 INVOLVED IN DENTAL, ORAL, 3175 02:05:49,911 --> 02:05:52,280 CRANIOFACIAL RESEARCH. 3176 02:05:52,280 --> 02:05:53,682 NEXT SLIDE PLEASE. 3177 02:05:53,682 --> 02:05:55,984 THIS PROGRAM SUPPORTS NEW 3178 02:05:55,984 --> 02:05:57,252 INVESTIGATORS WHOSE PROPOSED 3179 02:05:57,252 --> 02:06:00,756 RESEARCH ADDRESSES ANY OF THE 3180 02:06:00,756 --> 02:06:04,826 GOALS DESCRIBED IN THE PLAN AND 3181 02:06:04,826 --> 02:06:07,262 FALLS WITHIN NIDCR MISSION 3182 02:06:07,262 --> 02:06:07,763 AREAS. 3183 02:06:07,763 --> 02:06:09,464 RESEARCH PROJECTS IN BASIC AND 3184 02:06:09,464 --> 02:06:11,099 CLINICAL BEHAVIORAL AND 3185 02:06:11,099 --> 02:06:13,235 POPULATION SCIENCE AREAS ARE 3186 02:06:13,235 --> 02:06:14,703 COVERED UNDER THIS PROGRAM. 3187 02:06:14,703 --> 02:06:18,006 THIS PROGRAM DOES NOT SUPPORT 3188 02:06:18,006 --> 02:06:21,610 CLINICAL TRIALS OR VALIDATION 3189 02:06:21,610 --> 02:06:23,678 STUDIES, HOWEVER RESEARCH IN 3190 02:06:23,678 --> 02:06:24,746 BASIC, CLINICAL, BEHAVIORAL 3191 02:06:24,746 --> 02:06:27,649 TOPICS THAT DO NOT FUND UNDER 3192 02:06:27,649 --> 02:06:28,517 NIH CLINICAL TRIAL DEFINITION 3193 02:06:28,517 --> 02:06:32,788 ARE UNDER THE SCOPE OF THIS 3194 02:06:32,788 --> 02:06:33,021 PROGRAM. 3195 02:06:33,021 --> 02:06:36,191 THE NEW INVESTIGATORS PROGRAM IS 3196 02:06:36,191 --> 02:06:37,926 NOT INTENDED TO SUSTAIN RESEARCH 3197 02:06:37,926 --> 02:06:38,160 CAREERS. 3198 02:06:38,160 --> 02:06:39,995 IT IS EXPECTED THAT NEW 3199 02:06:39,995 --> 02:06:41,997 INVESTIGATORS WILL USE THIS 3200 02:06:41,997 --> 02:06:44,166 AWARD TO GENERATE THE FOUNDATION 3201 02:06:44,166 --> 02:06:47,502 TO SUPPORT GRANT APPLICATIONS 3202 02:06:47,502 --> 02:06:50,205 FOR LARGER AND LONGER-TERM R01 3203 02:06:50,205 --> 02:06:51,640 FUNDING. 3204 02:06:51,640 --> 02:06:52,174 NEXT SLIDE. 3205 02:06:52,174 --> 02:06:57,779 THIS PROGRAM IS LIMITED TO NEW 3206 02:06:57,779 --> 02:06:58,747 INVESTIGATORS BY NIH DEFINITION 3207 02:06:58,747 --> 02:07:00,515 NEW INVESTIGATOR IS RESEARCH 3208 02:07:00,515 --> 02:07:07,522 GRANT APPLICANT WHO HAS NOT 3209 02:07:07,522 --> 02:07:09,491 COMPETED SUCCESSFULLY FOR R01 OR 3210 02:07:09,491 --> 02:07:11,893 EQUIVALENT GRANT OR COOPERATIVE 3211 02:07:11,893 --> 02:07:12,527 AGREEMENT. 3212 02:07:12,527 --> 02:07:14,196 EXCLUDES INVESTIGATORS WHO WERE 3213 02:07:14,196 --> 02:07:17,499 AWARDED A PRIOR R21 FROM OTHER 3214 02:07:17,499 --> 02:07:18,767 INSTITUTES, FROM ANY INSTITUTE, 3215 02:07:18,767 --> 02:07:22,838 AND THOSE WITH MORE THAN ONE 3216 02:07:22,838 --> 02:07:24,039 NIDCR R03. 3217 02:07:24,039 --> 02:07:26,107 AS NIDCR SPECIFIC FUNDING 3218 02:07:26,107 --> 02:07:28,109 OPPORTUNITY, PEER REVIEW IS 3219 02:07:28,109 --> 02:07:30,912 CONDUCTED BY NIDCR SPECIAL 3220 02:07:30,912 --> 02:07:32,814 GRANTS REVIEW COMMITTEE. 3221 02:07:32,814 --> 02:07:35,083 UNIQUE TO THIS PAR APPLICANTS 3222 02:07:35,083 --> 02:07:39,354 MUST INCLUDE DESCRIPTION OF HOW 3223 02:07:39,354 --> 02:07:42,224 PROJECT WILL LEAD TO FRAMEWORK 3224 02:07:42,224 --> 02:07:48,763 FOR SUBSEQUENT R01 OR EQUIVALENT 3225 02:07:48,763 --> 02:07:50,832 APPLICATION, SCORABLE CRITERIA 3226 02:07:50,832 --> 02:07:52,801 BY SCIENTIFIC REVIEWERS. 3227 02:07:52,801 --> 02:07:55,537 MINIMUM LEVEL OF EFFORT OF 2.4 3228 02:07:55,537 --> 02:07:56,805 PERSON MONTHS IS EXPECTED FROM 3229 02:07:56,805 --> 02:08:00,275 THE P.I. 3230 02:08:00,275 --> 02:08:05,146 UNLIKE THE NIH PARENT MECHANISM 3231 02:08:05,146 --> 02:08:07,382 WHICH PROVIDES 50,000 DIRECT 3232 02:08:07,382 --> 02:08:10,252 COST PER YEAR FOR TWO YEARS THIS 3233 02:08:10,252 --> 02:08:15,390 ALLOWS FOR HIGHER AMOUNT OF 3234 02:08:15,390 --> 02:08:19,227 $100,000 OVER TWO YEARS. 3235 02:08:19,227 --> 02:08:19,527 NEXT SLIDE. 3236 02:08:19,527 --> 02:08:22,063 THIS PROGRAM WAS FIRST 3237 02:08:22,063 --> 02:08:24,266 ESTABLISHED AT NIDCR IN 2007 AND 3238 02:08:24,266 --> 02:08:28,303 SINCE THEN SIX PARS HAVE BEEN 3239 02:08:28,303 --> 02:08:28,937 ISSUED. 3240 02:08:28,937 --> 02:08:30,272 BASIC SCIENTISTS AND DENTAL 3241 02:08:30,272 --> 02:08:32,474 SCIENTISTS UTILIZE THIS PROGRAM 3242 02:08:32,474 --> 02:08:34,643 AND OVERALL SUCCESS RATE HAS 3243 02:08:34,643 --> 02:08:36,077 BEEN 22% FOR THIS PROGRAM OVER 3244 02:08:36,077 --> 02:08:39,481 THE YEARS. 3245 02:08:39,481 --> 02:08:41,149 NEXT SLIDE. 3246 02:08:41,149 --> 02:08:43,818 YOU CAN CLICK COMPLETELY. 3247 02:08:43,818 --> 02:08:46,154 SO, RECENT ANALYSIS OF THE 3248 02:08:46,154 --> 02:08:48,123 R03s OVER THE PAST YEARS 3249 02:08:48,123 --> 02:08:51,960 SHOWED THAT THE R03 AWARDEES ARE 3250 02:08:51,960 --> 02:08:56,131 MORE LIKELY TO APPLY FOR R01 3251 02:08:56,131 --> 02:09:03,038 COMPARED TO UNSUCCESSFUL 3252 02:09:03,038 --> 02:09:03,371 COUNTERPARTS. 3253 02:09:03,371 --> 02:09:04,906 R03 AWARDEE WAS 2.4 TIMES MORE 3254 02:09:04,906 --> 02:09:08,543 LIKELY TO BE AWARDED SUBSEQUENT 3255 02:09:08,543 --> 02:09:10,145 R01 COMPARED TO COUNTERPARTS. 3256 02:09:10,145 --> 02:09:12,013 ALSO THESE AWARDEES WERE MORE 3257 02:09:12,013 --> 02:09:14,749 LIKELY TO BE AWARDED AN R01 3258 02:09:14,749 --> 02:09:18,486 COMPARED TO STANDARD NIDCR NEW 3259 02:09:18,486 --> 02:09:21,456 INVESTIGATOR WHO NEVER USED THIS 3260 02:09:21,456 --> 02:09:22,991 R03 PROGRAM. 3261 02:09:22,991 --> 02:09:24,092 SO OVERALL THIS FUNDING 3262 02:09:24,092 --> 02:09:25,927 OPPORTUNITY CONTINUES TO BE WELL 3263 02:09:25,927 --> 02:09:28,129 RECEIVED BY THE COMMUNITY, 3264 02:09:28,129 --> 02:09:30,098 ESPECIALLY BY THOSE HAVING NO 3265 02:09:30,098 --> 02:09:32,801 PRIOR EXPERIENCE WITH THE PEER 3266 02:09:32,801 --> 02:09:33,368 REVIEW PROCESS. 3267 02:09:33,368 --> 02:09:37,005 AT THIS POINT I WILL STOP AND 3268 02:09:37,005 --> 02:09:39,074 TURN IT OVER FOR COUNCIL MEMBERS 3269 02:09:39,074 --> 02:09:41,176 DR. KREBSBACH AND DR. NOR FOR 3270 02:09:41,176 --> 02:09:45,847 DISCUSSION OF THIS CONCEPT. 3271 02:09:45,847 --> 02:09:49,017 THANK YOU. 3272 02:09:49,017 --> 02:09:50,652 >> THANK YOU, PREETHI. 3273 02:09:50,652 --> 02:09:52,721 I'M TRYING TO START MY VIDEO 3274 02:09:52,721 --> 02:09:59,961 HERE. 3275 02:09:59,961 --> 02:10:00,428 OKAY. 3276 02:10:00,428 --> 02:10:01,196 VERY GOOD. 3277 02:10:01,196 --> 02:10:03,832 YEAH, SO THANK YOU, PREETHI, FOR 3278 02:10:03,832 --> 02:10:04,566 THE PRESENTATION. 3279 02:10:04,566 --> 02:10:07,002 I WANT TO START BY SAYING THAT 3280 02:10:07,002 --> 02:10:10,038 I'M IN FULL SUPPORT OF THE 3281 02:10:10,038 --> 02:10:11,606 RENEWAL OF THE NIDCR R03 3282 02:10:11,606 --> 02:10:16,811 PROGRAM, THE GOAL TO ENABLE NEW 3283 02:10:16,811 --> 02:10:18,613 INVESTIGATORS TO GENERATE DATA 3284 02:10:18,613 --> 02:10:21,616 FOR SUBSEQUENT R01 APPLICATION, 3285 02:10:21,616 --> 02:10:23,551 IMPORTANTLY THIS PROJECT, THIS 3286 02:10:23,551 --> 02:10:24,719 PROGRAM, INCLUDES SPECIFIC 3287 02:10:24,719 --> 02:10:27,088 SECTION ON HOW THE WORK FUNDED 3288 02:10:27,088 --> 02:10:30,158 IN THE R03 WILL BE USED TO R01 3289 02:10:30,158 --> 02:10:31,593 WHICH I BELIEVE STIMULATES 3290 02:10:31,593 --> 02:10:33,695 APPLICANT TO DEVELOP LOGICAL 3291 02:10:33,695 --> 02:10:35,030 LONG-TERM RESEARCH PROGRAM. 3292 02:10:35,030 --> 02:10:36,531 AGAIN, THE REASONS WHY I SUPPORT 3293 02:10:36,531 --> 02:10:39,701 THE RENEWAL OF THE R03 PROGRAM 3294 02:10:39,701 --> 02:10:41,569 ARE FIRSTLY THE PROGRAM 3295 02:10:41,569 --> 02:10:43,538 ADDRESSES THE URGENT NEED TO 3296 02:10:43,538 --> 02:10:45,273 FOSTER CAREERS OF HIGHLY 3297 02:10:45,273 --> 02:10:47,242 QUALIFIED COLLEAGUES IN DENTAL 3298 02:10:47,242 --> 02:10:48,810 OR CRANIOFACIAL RESEARCH, AND 3299 02:10:48,810 --> 02:10:51,212 THERE'S AN OBVIOUS NEED FOR MORE 3300 02:10:51,212 --> 02:10:56,117 INVESTIGATORS IN THE FIELD. 3301 02:10:56,117 --> 02:10:57,318 SECOND, THE FUNDING PROVIDED 3302 02:10:57,318 --> 02:11:00,822 THROUGH THIS PROGRAM OF UP TO 3303 02:11:00,822 --> 02:11:02,891 $200,000 IN TWO YEARS SEEMS TO 3304 02:11:02,891 --> 02:11:04,859 BE ADEQUATE AND ALIGN VERY WELL 3305 02:11:04,859 --> 02:11:08,596 WITH INTENT OF THE PROGRAM. 3306 02:11:08,596 --> 02:11:10,131 AND THIRD, HISTORICAL OUTCOME 3307 02:11:10,131 --> 02:11:11,666 THAT SHOWS INCREASE IN 3308 02:11:11,666 --> 02:11:15,270 PROBABILITY TO GET AN R01 FROM 3309 02:11:15,270 --> 02:11:21,309 21% TO 51% FOR R03 AWARDEES 3310 02:11:21,309 --> 02:11:22,510 CLEARLY DEMONSTRATES SUCCESSFUL 3311 02:11:22,510 --> 02:11:25,447 IMPACT OF THIS PROGRAM, AND 3312 02:11:25,447 --> 02:11:28,116 CLEARLY SHOWS ALSO THAT THIS 3313 02:11:28,116 --> 02:11:31,019 PROGRAM IS SUPPORTING THE 3314 02:11:31,019 --> 02:11:32,787 TRANSITION OF NEW INVESTIGATORS 3315 02:11:32,787 --> 02:11:33,988 IN INDEPENDENT RESEARCH CAREERS, 3316 02:11:33,988 --> 02:11:37,192 SO ALL IN ALL I THINK THIS IS 3317 02:11:37,192 --> 02:11:38,960 INCREDIBLY IMPORTANT PROGRAM AND 3318 02:11:38,960 --> 02:11:44,299 I STRONGLY SUPPORT RENEWAL. 3319 02:11:44,299 --> 02:11:44,732 THANK YOU. 3320 02:11:44,732 --> 02:11:50,305 >> THANK YOU. 3321 02:11:50,305 --> 02:11:50,705 >> DR. KREBSBACH? 3322 02:11:50,705 --> 02:11:56,678 >> OKAY, THANK YOU. 3323 02:11:56,678 --> 02:11:59,447 I THINK PREETHI DID A REALLY 3324 02:11:59,447 --> 02:12:00,415 NICE JOB SUMMARIZING THIS. 3325 02:12:00,415 --> 02:12:05,687 I DON'T HAVE MUCH MORE TO ADD 3326 02:12:05,687 --> 02:12:10,024 THAN WHAT JACQUES DISPLAYED. 3327 02:12:10,024 --> 02:12:12,227 IT'S REALLY GOOD EVENT AT DCR TO 3328 02:12:12,227 --> 02:12:15,497 INVEST IN THESE EARLY 3329 02:12:15,497 --> 02:12:17,031 INVESTIGATORS, I THINK IT'S 3330 02:12:17,031 --> 02:12:18,666 REALLY IMPORTANT THAT TRACK 3331 02:12:18,666 --> 02:12:20,802 RECORD SEEMS TO BE PRETTY GOOD. 3332 02:12:20,802 --> 02:12:24,806 I DO REALLY LIKE THE INCREASE IN 3333 02:12:24,806 --> 02:12:26,007 THE BUDGET. 3334 02:12:26,007 --> 02:12:27,876 I THINK THAT GIVES MEANINGFUL 3335 02:12:27,876 --> 02:12:29,410 AMOUNT TO GET SOMEONE STARTED, 3336 02:12:29,410 --> 02:12:30,845 REALLY WHAT THIS PROGRAM IS 3337 02:12:30,845 --> 02:12:33,448 DESIGNED TO DO TO GET SOMEONE 3338 02:12:33,448 --> 02:12:38,720 STARTED ON A CAREER FOCUS. 3339 02:12:38,720 --> 02:12:42,624 I ALSO LIKE THE RESEARCH, WHAT 3340 02:12:42,624 --> 02:12:44,726 IS IT, FUTURE RESEARCH PLAN, 3341 02:12:44,726 --> 02:12:46,127 FORCES THE INVESTIGATOR TO BE 3342 02:12:46,127 --> 02:12:49,264 THINKING ABOUT A PATH FORWARD 3343 02:12:49,264 --> 02:12:52,967 AND NOT JUST TRYING TO DO A 3344 02:12:52,967 --> 02:12:57,105 ONE-OFF PROJECT AND FITS THE 3345 02:12:57,105 --> 02:12:58,406 WHOLE GOAL TOGETHER. 3346 02:12:58,406 --> 02:13:01,543 I DO MAYBE HAVE ONE QUESTION FOR 3347 02:13:01,543 --> 02:13:02,377 DISCUSSION ALTHOUGH I HAVE TO 3348 02:13:02,377 --> 02:13:07,615 SAY I SUPPORT THIS FULLY AS 3349 02:13:07,615 --> 02:13:10,585 WELL, IS THAT EVEN THOUGH IT'S 3350 02:13:10,585 --> 02:13:13,321 IMPORTANT TO HAVE THIS PIPELINE, 3351 02:13:13,321 --> 02:13:15,523 THESE INVESTIGATORS WHO APPLY 3352 02:13:15,523 --> 02:13:18,660 FOR THESE AWARDS AND THOSE WHO 3353 02:13:18,660 --> 02:13:20,094 ARE AWARDED THEM STILL HAVE TO 3354 02:13:20,094 --> 02:13:23,164 BE IN AN ENVIRONMENT WHERE THEY 3355 02:13:23,164 --> 02:13:23,464 CAN THRIVE. 3356 02:13:23,464 --> 02:13:26,234 SO I THINK -- I DON'T KNOW IF 3357 02:13:26,234 --> 02:13:29,737 THERE'S SOMETHING, A MENTORING 3358 02:13:29,737 --> 02:13:31,506 REQUIREMENT HERE, BECAUSE WHILE 3359 02:13:31,506 --> 02:13:38,613 I'M OPTIMISTIC FOR THIS PROJECT, 3360 02:13:38,613 --> 02:13:40,281 I'M NOT -- MANY ENVIRONMENTS OR 3361 02:13:40,281 --> 02:13:41,416 SCHOOLS WHERE THESE PEOPLE ARE 3362 02:13:41,416 --> 02:13:43,585 TRYING TO GET THEIR CAREER 3363 02:13:43,585 --> 02:13:46,120 STARTED, I THINK THAT THE 3364 02:13:46,120 --> 02:13:47,889 ENVIRONMENT AND THEIR MENTORING 3365 02:13:47,889 --> 02:13:51,159 TEAM REALLY IS ESSENTIAL AS WELL 3366 02:13:51,159 --> 02:13:53,294 AS THE AWARDING OF THESE TYPE OF 3367 02:13:53,294 --> 02:13:58,499 GRANTS AND INCREASE OF THE 3368 02:13:58,499 --> 02:13:58,733 BUDGET. 3369 02:13:58,733 --> 02:14:00,902 I QUESTION WHETHER THERE IS 3370 02:14:00,902 --> 02:14:03,404 SOMETHING ABOUT MENTORING AND 3371 02:14:03,404 --> 02:14:06,040 THE ENVIRONMENT SO THAT THESE 3372 02:14:06,040 --> 02:14:06,808 INDIVIDUALS CAN THRIVE 3373 02:14:06,808 --> 02:14:08,343 REGARDLESS OF WHAT INSTITUTION 3374 02:14:08,343 --> 02:14:09,510 THEY ARE IN. 3375 02:14:09,510 --> 02:14:13,915 >> YEAH, WE DO -- SO I THINK A 3376 02:14:13,915 --> 02:14:16,251 LOT OF THE APPLICANTS HAVE SOME 3377 02:14:16,251 --> 02:14:17,885 KIND OF INDEPENDENT POSITION 3378 02:14:17,885 --> 02:14:20,488 WHEN THEY APPLY, AND IN SOME 3379 02:14:20,488 --> 02:14:24,225 CASES WHERE THEY DO -- THEY ARE 3380 02:14:24,225 --> 02:14:27,729 AT SENIOR POSTDOC LEVEL, SENIOR 3381 02:14:27,729 --> 02:14:29,931 POSITION, THAT KIND OF HAS 3382 02:14:29,931 --> 02:14:30,898 INDEPENDENT APPOINTMENT, WE DO 3383 02:14:30,898 --> 02:14:33,668 REQUEST LETTER OF SUPPORT FROM 3384 02:14:33,668 --> 02:14:35,303 THE DEAN OR DEPARTMENT CHAIR, 3385 02:14:35,303 --> 02:14:39,674 DESCRIBING WHAT IS THE NATURE OF 3386 02:14:39,674 --> 02:14:40,475 THE APPOINTMENT, INSTITUTIONAL 3387 02:14:40,475 --> 02:14:44,379 COMPLIMENT TO P.I. IN TERMS OF 3388 02:14:44,379 --> 02:14:45,813 GENERAL RESOURCES AND TECHNICAL 3389 02:14:45,813 --> 02:14:48,449 ASSISTANCE IN TERMS OF SEEING 3390 02:14:48,449 --> 02:14:49,617 SUCCESS AND HOPEFULLY THAT 3391 02:14:49,617 --> 02:14:56,024 ADDRESSES PART OF YOUR QUESTION. 3392 02:14:56,024 --> 02:14:56,457 >> YEAH, THANK YOU. 3393 02:14:56,457 --> 02:15:00,128 >> I CAN ADD TO YOUR COMMENT? 3394 02:15:00,128 --> 02:15:03,097 UCLA MODELS SO MANY BEST 3395 02:15:03,097 --> 02:15:04,165 PRACTICES, NURTURING EARLY-STAGE 3396 02:15:04,165 --> 02:15:05,066 INVESTIGATORS. 3397 02:15:05,066 --> 02:15:10,004 DO YOU HAVE COMMUNITIES OF NOT 3398 02:15:10,004 --> 02:15:11,639 NECESSARILY R03s AND R21s 3399 02:15:11,639 --> 02:15:14,042 BUT DEVELOPING INVESTIGATORS 3400 02:15:14,042 --> 02:15:16,344 THAT ACTUALLY SHARE KNOWLEDGE 3401 02:15:16,344 --> 02:15:18,246 ALMOST LIKE A T32 UMBRELLA 3402 02:15:18,246 --> 02:15:21,716 PROBLEM WOULD OFFER, DO YOU HAVE 3403 02:15:21,716 --> 02:15:22,016 THOSE? 3404 02:15:22,016 --> 02:15:23,651 >> YEAH, WE DO. 3405 02:15:23,651 --> 02:15:25,486 AND THERE'S MANY DENTAL SCHOOLS, 3406 02:15:25,486 --> 02:15:28,690 I DIDN'T MEAN TO TAKE A SHOT AT 3407 02:15:28,690 --> 02:15:31,693 ANY SPECIFIC SCHOOL, WHETHER A 3408 02:15:31,693 --> 02:15:32,760 DENTAL SCHOOL OR NOT. 3409 02:15:32,760 --> 02:15:34,829 BUT YOU DO HAVE TO HAVE AN 3410 02:15:34,829 --> 02:15:37,031 ENVIRONMENT, AND WE DO HAVE 3411 02:15:37,031 --> 02:15:38,499 FORMAL MENTORING TEAMS AND 3412 02:15:38,499 --> 02:15:42,170 MENTORING COMMITTEES, I KNOW 3413 02:15:42,170 --> 02:15:43,604 SPECIFICALLY AT MICHIGAN THE -- 3414 02:15:43,604 --> 02:15:47,308 THIS IS PROBABLY 10 OR 15 YEARS 3415 02:15:47,308 --> 02:15:49,944 AGO, THEY LAUNCHED ACTUALLY I 3416 02:15:49,944 --> 02:15:53,681 THINK WHAT WAS CALLED A LAUNCH 3417 02:15:53,681 --> 02:15:55,350 PROGRAM, IT HAD MENTORS NOT ONLY 3418 02:15:55,350 --> 02:15:57,752 FROM SCHOOL OF DENTISTRY BUT 3419 02:15:57,752 --> 02:15:58,553 APPROPRIATE OTHER UNIVERSITY 3420 02:15:58,553 --> 02:16:01,622 SCHOOL LIKE MEDICAL SCHOOL OR 3421 02:16:01,622 --> 02:16:01,923 ENGINEERING. 3422 02:16:01,923 --> 02:16:02,190 >> RIGHT. 3423 02:16:02,190 --> 02:16:05,426 >> THEY WOULD BE TASKED REALLY 3424 02:16:05,426 --> 02:16:09,997 FOR GUIDING THIS PERSON TO 3425 02:16:09,997 --> 02:16:10,231 SUCCESS. 3426 02:16:10,231 --> 02:16:11,099 >> RIGHT. 3427 02:16:11,099 --> 02:16:14,702 AND AT MICHIGAN YOU HELPED LEAD 3428 02:16:14,702 --> 02:16:17,772 THE BIOENGINEERING SCHOOL THAT 3429 02:16:17,772 --> 02:16:18,206 DID THAT. 3430 02:16:18,206 --> 02:16:21,075 REMEMBER THEY HAD DINNER 3431 02:16:21,075 --> 02:16:22,844 SESSIONS, STUDENT LED, ALWAYS 3432 02:16:22,844 --> 02:16:24,579 EXPERTS AVAILABLE TO COME BY AND 3433 02:16:24,579 --> 02:16:25,780 TALK, RIGHT? 3434 02:16:25,780 --> 02:16:26,314 >> FOR SURE. 3435 02:16:26,314 --> 02:16:31,018 I THINK AS YOU LOOK FORWARD TO 3436 02:16:31,018 --> 02:16:33,654 THE ACTUAL PURPOSE OF THIS KIND 3437 02:16:33,654 --> 02:16:35,857 OF PROJECT, IS TO INCREASE THE 3438 02:16:35,857 --> 02:16:38,793 WORKFORCE AND SET PEOPLE UP FOR 3439 02:16:38,793 --> 02:16:40,561 SUCCESSFUL CAREER, IT'S MORE 3440 02:16:40,561 --> 02:16:43,531 THAN JUST ONE PERSON GIVING, YOU 3441 02:16:43,531 --> 02:16:46,167 KNOW, A TWO-YEAR GRANT, RIGHT? 3442 02:16:46,167 --> 02:16:47,769 THEY NEED TO BE IN AN 3443 02:16:47,769 --> 02:16:48,836 ENVIRONMENT YOU CAN DO 3444 02:16:48,836 --> 02:16:51,806 EVERYTHING POSSIBLE TO GUIDE 3445 02:16:51,806 --> 02:16:56,110 THIS PERSON INTO THE NEXT PHASE 3446 02:16:56,110 --> 02:17:00,181 IN THIS HOPEFULLY SUCCESSFUL 3447 02:17:00,181 --> 02:17:00,782 R01-TYPE GRANT. 3448 02:17:00,782 --> 02:17:03,117 >> THE BEST THING THAT COMES TO 3449 02:17:03,117 --> 02:17:05,386 MIND, THE FUTURE PROGRAM, EARLY 3450 02:17:05,386 --> 02:17:07,889 STAGE CAREER FACULTY WITH HIGH 3451 02:17:07,889 --> 02:17:10,992 DEGREE OF SUCCESS, BUT THEY 3452 02:17:10,992 --> 02:17:12,059 DRIVE THEIR MENTORING NATIONWIDE 3453 02:17:12,059 --> 02:17:13,928 FROM A NETWORK OF MENTORS BUT 3454 02:17:13,928 --> 02:17:19,500 YOU CAN ALSO HAVE THAT LOCALLY 3455 02:17:19,500 --> 02:17:25,640 FOR RESEARCH, YEAH. 3456 02:17:25,640 --> 02:17:25,840 JOSE? 3457 02:17:25,840 --> 02:17:31,312 >> YEAH, I WAS WONDERING IF THIS 3458 02:17:31,312 --> 02:17:33,147 MECHANISM IN ADDITION TO FOCUS 3459 02:17:33,147 --> 02:17:34,715 FOR JUNIOR INVESTIGATORS COULD 3460 02:17:34,715 --> 02:17:38,753 BE FOR PEOPLE OUTSIDE THE FIELD, 3461 02:17:38,753 --> 02:17:39,854 DENTAL RESEARCH, TO BE 3462 02:17:39,854 --> 02:17:43,157 COMPLEMENTARY TO WHAT THE FIELD 3463 02:17:43,157 --> 02:17:44,358 IS NEEDED, LIKE NEED TO BE LIKE, 3464 02:17:44,358 --> 02:17:46,127 YOU KNOW, WORKING IN A DENTAL 3465 02:17:46,127 --> 02:17:51,499 SCHOOL, THEY COULD BE WORKING IN 3466 02:17:51,499 --> 02:17:52,567 NURSING SCHOOL, MEDICAL SCHOOL, 3467 02:17:52,567 --> 02:17:54,235 AND, YOU KNOW, IN THAT CASE IT 3468 02:17:54,235 --> 02:17:56,304 COULD BE GOOD IF THE APPLICATION 3469 02:17:56,304 --> 02:17:59,073 IN ADDITION TO HAVE A FUTURE 3470 02:17:59,073 --> 02:18:01,909 PLANS FOR RESEARCH YOU HAVE LIKE 3471 02:18:01,909 --> 02:18:04,879 A MENTORING STATEMENT OR SOME 3472 02:18:04,879 --> 02:18:06,747 KIND OF, YOU KNOW, THERE WILL BE 3473 02:18:06,747 --> 02:18:08,516 THESE PEOPLE IN PLACE, SAY 3474 02:18:08,516 --> 02:18:10,251 MEDICAL SCHOOL PEOPLE, OR DENTAL 3475 02:18:10,251 --> 02:18:12,887 SCHOOL, THAT CAN ACTUALLY HELP 3476 02:18:12,887 --> 02:18:15,189 THEM NAVIGATE THIS KIND OF NEW 3477 02:18:15,189 --> 02:18:17,024 AREA BECAUSE, YOU KNOW, I THINK 3478 02:18:17,024 --> 02:18:18,025 THAT SOMETIMES WE CANNOT ANSWER 3479 02:18:18,025 --> 02:18:18,993 ALL THE QUESTIONS BECAUSE WE 3480 02:18:18,993 --> 02:18:23,164 DON'T HAVE THE RIGHT PEOPLE AND 3481 02:18:23,164 --> 02:18:24,832 SOMETIMES THERE ARE PEOPLE IN 3482 02:18:24,832 --> 02:18:25,933 DIFFERENT AREA, PEOPLE MAY NOT 3483 02:18:25,933 --> 02:18:28,336 THINK IF THEY ARE DOING 3484 02:18:28,336 --> 02:18:30,938 NEUROSCIENCE, THEY MAY NOT APPLY 3485 02:18:30,938 --> 02:18:34,542 FOR A GRANT APPLICATION THAT 3486 02:18:34,542 --> 02:18:35,776 COMES FROM DENTAL INSTITUTE, SO 3487 02:18:35,776 --> 02:18:37,612 TO BRING THESE PEOPLE IN, IN 3488 02:18:37,612 --> 02:18:39,914 ADDITION TO HAVING PROPOSED LIKE 3489 02:18:39,914 --> 02:18:43,651 A MENTORING PLAN, SOMETHING LIKE 3490 02:18:43,651 --> 02:18:44,085 THAT. 3491 02:18:44,085 --> 02:18:47,154 >> YEAH, YEAH, I JUST WANT -- I 3492 02:18:47,154 --> 02:18:48,489 DO RECOGNIZE THAT POINT AND 3493 02:18:48,489 --> 02:18:51,759 THANKS FOR BRINGING IT UP. 3494 02:18:51,759 --> 02:18:52,960 THE GRANT MECHANISM, 3495 02:18:52,960 --> 02:18:54,295 ANNOUNCEMENT, NO RESTRICTIONS 3496 02:18:54,295 --> 02:18:55,830 WHAT KIND OF INSTITUTION OR 3497 02:18:55,830 --> 02:18:57,298 DEPARTMENT IT WOULD BELONG TO. 3498 02:18:57,298 --> 02:18:59,300 AND WE DO A LOT OF OUTREACH AT 3499 02:18:59,300 --> 02:19:02,069 THE VARIOUS MEETINGS THAT WE 3500 02:19:02,069 --> 02:19:04,572 ATTEND ABOUT THIS PROGRAM, 3501 02:19:04,572 --> 02:19:05,306 HOPEFULLY WE'RE REACHING ACROSS 3502 02:19:05,306 --> 02:19:06,774 BECAUSE THIS IS NOT SPECIFIC TO 3503 02:19:06,774 --> 02:19:08,075 ANY PROGRAM. 3504 02:19:08,075 --> 02:19:16,183 IT COVERS ALL OF NIDCR MISSION 3505 02:19:16,183 --> 02:19:16,751 AREAS. 3506 02:19:16,751 --> 02:19:17,718 IRRESPECTIVE OF APPLICANT 3507 02:19:17,718 --> 02:19:18,019 BACKGROUND. 3508 02:19:18,019 --> 02:19:20,121 WE TRY SPREAD THE WORD. 3509 02:19:20,121 --> 02:19:24,659 ON PAPER THERE'S NO RESTRICTION. 3510 02:19:24,659 --> 02:19:28,029 >> THE OTHER QUESTION IS DO YOU 3511 02:19:28,029 --> 02:19:32,099 HAVE ANY FOLLOW-UP, LIKE FOR 3512 02:19:32,099 --> 02:19:36,037 EXAMPLE DO YOU PUT ANY TOGETHER, 3513 02:19:36,037 --> 02:19:39,273 YOU KNOW, THAT COULD BE DONE 3514 02:19:39,273 --> 02:19:40,775 LATER ON SO THEY GET TO KNOW 3515 02:19:40,775 --> 02:19:42,310 EACH OTHER AND SUPPORT EACH 3516 02:19:42,310 --> 02:19:44,845 OTHER BECAUSE EVENTUALLY THIS 3517 02:19:44,845 --> 02:19:48,349 COULD BE INDIVIDUAL OR PRINCIPAL 3518 02:19:48,349 --> 02:19:49,250 INVESTIGATORS THAT FORM 3519 02:19:49,250 --> 02:19:49,850 COLLABORATIONS DOWN THE ROAD. 3520 02:19:49,850 --> 02:19:52,820 I DON'T KNOW IF THAT'S SOMETHING 3521 02:19:52,820 --> 02:19:55,556 BECAUSE IT'S NOT AN R03, TO GIVE 3522 02:19:55,556 --> 02:19:57,658 INDIVIDUALS, MAYBE YOU'RE TRYING 3523 02:19:57,658 --> 02:20:02,096 TO PREPARE THE NEXT COHORT OF 3524 02:20:02,096 --> 02:20:02,897 INVESTIGATORS. 3525 02:20:02,897 --> 02:20:04,799 HAVING SOME INITIATIVES TO GET 3526 02:20:04,799 --> 02:20:06,067 TOGETHER, GET TO KNOW EACH 3527 02:20:06,067 --> 02:20:09,770 OTHER, THAT'S GOING TO ACTUALLY 3528 02:20:09,770 --> 02:20:11,505 INCREASE CHANCES TO SUCCESS. 3529 02:20:11,505 --> 02:20:13,407 >> YEAH, YEAH. 3530 02:20:13,407 --> 02:20:17,011 THANK YOU. 3531 02:20:17,011 --> 02:20:19,513 >> ANY OTHER COMMENTS OR 3532 02:20:19,513 --> 02:20:23,384 QUESTIONS? 3533 02:20:23,384 --> 02:20:24,986 IF NOT, WOULD A MEMBER OF 3534 02:20:24,986 --> 02:20:32,627 COUNCIL LIKE TO MAKE A MOTION TO 3535 02:20:32,627 --> 02:20:33,160 APPROVE THIS CONCEPT? 3536 02:20:33,160 --> 02:20:36,130 >> JOSE. 3537 02:20:36,130 --> 02:20:36,864 A SECOND? 3538 02:20:36,864 --> 02:20:37,231 >> SECOND, PAUL. 3539 02:20:37,231 --> 02:20:40,101 >> ALL IN FAVOR? 3540 02:20:40,101 --> 02:20:40,334 >> AYE. 3541 02:20:40,334 --> 02:20:40,835 >> AYE. 3542 02:20:40,835 --> 02:20:41,202 >> AYE. 3543 02:20:41,202 --> 02:20:42,570 >> YES. 3544 02:20:42,570 --> 02:20:45,039 >> ANY OPPOSED? 3545 02:20:45,039 --> 02:20:46,907 ALL RIGHT. 3546 02:20:46,907 --> 02:20:48,743 SO I THINK WE'RE FINISHED WITH 3547 02:20:48,743 --> 02:20:50,811 OUR FIRST SESSION. 3548 02:20:50,811 --> 02:20:53,147 WE'LL NOW TAKE A 30-MINUTE 3549 02:20:53,147 --> 02:21:00,488 BREAK, AND RETURN AT 1 P.M. 3550 02:21:00,488 --> 02:21:01,055 >> THANK YOU. 3551 02:21:01,055 --> 02:21:04,523 [LUNCH RECESS] 3552 02:21:06,571 --> 02:21:08,606 >> I'D LIKE TO WELCOME EVERYONE 3553 02:21:08,606 --> 02:21:13,077 BACK TO COUNCIL. 3554 02:21:13,077 --> 02:21:16,815 NEXT A PRESENTATION BY DR. DANA 3555 02:21:16,815 --> 02:21:22,320 GRAVES, PROVIDING AN UPDATE ON 3556 02:21:22,320 --> 02:21:23,588 THE WORKING GROUP'S ACTIVITIES. 3557 02:21:23,588 --> 02:21:25,557 WE CAN TURN IT OVER TO DR. 3558 02:21:25,557 --> 02:21:33,064 GRAVES AND CAN YOU SHARE YOUR 3559 02:21:33,064 --> 02:21:33,798 SCREEN FOR SLIDES. 3560 02:21:33,798 --> 02:21:36,100 >> CAN YOU SEE MY SCREEN? 3561 02:21:36,100 --> 02:21:37,068 >> YES. 3562 02:21:37,068 --> 02:21:38,903 >> SO FAR NO TECHNICAL 3563 02:21:38,903 --> 02:21:39,370 CHALLENGES. 3564 02:21:39,370 --> 02:21:43,508 THANK YOU, LYNN, FOR INVITING 3565 02:21:43,508 --> 02:21:44,609 INVITING ME TO GIVE THIS 3566 02:21:44,609 --> 02:21:49,314 PRESENTATION ON THE WORKING 3567 02:21:49,314 --> 02:21:50,381 GROUP ON THE WORKFORCE, THE 3568 02:21:50,381 --> 02:21:53,918 CHARGE TO DEVELOP AND RECOMMEND 3569 02:21:53,918 --> 02:21:55,420 EVIDENCE-BASED APPROACHES TO 3570 02:21:55,420 --> 02:21:56,621 SUSTAINABLE RECRUIT, TRAIN, 3571 02:21:56,621 --> 02:21:57,755 RETAIN RESEARCHERS WHO HAVE 3572 02:21:57,755 --> 02:22:01,025 KNOWLEDGE AND SKILLS TO BUILD A 3573 02:22:01,025 --> 02:22:03,228 DIVERSE DENTAL, ORAL, 3574 02:22:03,228 --> 02:22:05,830 CRANIOFACIAL AND 3575 02:22:05,830 --> 02:22:06,698 DENTIST-SCIENTIST RESEARCH 3576 02:22:06,698 --> 02:22:07,332 WORKFORCE. 3577 02:22:07,332 --> 02:22:10,869 THE AREA I'M GOING TO DISCUSS 3578 02:22:10,869 --> 02:22:11,903 TODAY IS NOT RECOMMENDATIONS 3579 02:22:11,903 --> 02:22:14,038 WHICH WE'RE IN THE PROCESS OF 3580 02:22:14,038 --> 02:22:16,040 DEVELOPING BUT TWO AREAS OF 3581 02:22:16,040 --> 02:22:17,342 FOCUS WE THINK ARE VERY 3582 02:22:17,342 --> 02:22:19,077 IMPORTANT, PART OF MY GOAL TODAY 3583 02:22:19,077 --> 02:22:29,621 WOULD BE TO GET YOUR FEEDBACK ON 3584 02:22:30,088 --> 02:22:30,455 WHAT WE'RE THINKING. 3585 02:22:30,455 --> 02:22:34,726 SO MEMBERS OF THE WORKING GROUP 3586 02:22:34,726 --> 02:22:40,732 ARE DIVERSE, ALL HAVE A RANGE OF 3587 02:22:40,732 --> 02:22:41,933 EXPERIENCE WORKING WITH DOC 3588 02:22:41,933 --> 02:22:44,469 TRAINEES. 3589 02:22:44,469 --> 02:22:45,570 THERE ARE TWO CONSIDERATIONS 3590 02:22:45,570 --> 02:22:47,672 THAT THE WORKFORCE WAS ENGAGED 3591 02:22:47,672 --> 02:22:47,906 IN. 3592 02:22:47,906 --> 02:22:51,843 ONE OF THEM IS HOW TO ENHANCE 3593 02:22:51,843 --> 02:22:54,879 TRAINING WITHOUT SIMPLY ASKING 3594 02:22:54,879 --> 02:22:56,948 FOR MORE FUNDING. 3595 02:22:56,948 --> 02:22:58,816 SECOND IS THE RECOGNITION THERE 3596 02:22:58,816 --> 02:23:01,319 ARE LIMITS IN AVAILABLE DATA IN 3597 02:23:01,319 --> 02:23:05,823 WHICH TO EVALUATE THESE 3598 02:23:05,823 --> 02:23:06,291 PROGRAMS. 3599 02:23:06,291 --> 02:23:10,728 SO, TO RESPOND TO THESE 3600 02:23:10,728 --> 02:23:12,397 CONSIDERATIONS, WE ARE GOING TO 3601 02:23:12,397 --> 02:23:15,033 PROPOSE THE DEVELOPMENT OF TWO 3602 02:23:15,033 --> 02:23:15,466 OFFICES. 3603 02:23:15,466 --> 02:23:19,737 ONE OFFICE WOULD BE DEDICATED TO 3604 02:23:19,737 --> 02:23:20,939 COLLABORATING WITH PROFESSIONAL 3605 02:23:20,939 --> 02:23:24,542 ORGANIZATIONS, TO DEVELOP 3606 02:23:24,542 --> 02:23:26,711 SYNERGIES WITH EXISTING 3607 02:23:26,711 --> 02:23:27,111 PROGRAMS. 3608 02:23:27,111 --> 02:23:29,447 THE SECOND OFFICE WOULD BE 3609 02:23:29,447 --> 02:23:33,384 DEVOTED TO OUTCOME MEASURES AND 3610 02:23:33,384 --> 02:23:35,586 THE APPLICATION OF ADVANCED 3611 02:23:35,586 --> 02:23:37,555 ANALYTICS TO ASSESS TRAINEES, 3612 02:23:37,555 --> 02:23:43,394 TRAINING PROGRAMS, AND TO ASSESS 3613 02:23:43,394 --> 02:23:45,129 THE DOC WORKFORCE NEEDS. 3614 02:23:45,129 --> 02:23:50,134 SO, THE CREATION OF AN OFFICE TO 3615 02:23:50,134 --> 02:23:51,469 FACILITATE COLLABORATIONS WITH 3616 02:23:51,469 --> 02:23:57,709 NIDCR AND PROFESSIONAL SOCIETY 3617 02:23:57,709 --> 02:23:58,476 OF PROFESSIONAL FOUNDATIONS 3618 02:23:58,476 --> 02:24:01,846 WITHIN UNIVERSITIES IS DONE IN 3619 02:24:01,846 --> 02:24:02,513 RECOGNITION THAT THERE ARE 3620 02:24:02,513 --> 02:24:04,615 SEVERAL COMMON GOALS THEY SHARE. 3621 02:24:04,615 --> 02:24:07,452 WHEN WE MET WITH THE DIFFERENT 3622 02:24:07,452 --> 02:24:08,353 REPRESENTATIVES FROM THESE 3623 02:24:08,353 --> 02:24:10,955 GROUPS, THE WORKING GROUP WAS 3624 02:24:10,955 --> 02:24:13,691 VERY IMPRESSED WITH THEIR 3625 02:24:13,691 --> 02:24:15,126 ENTHUSIASM AND THEIR DESIRE TO 3626 02:24:15,126 --> 02:24:17,328 COLLABORATE WITH NIDCR BUT WHAT 3627 02:24:17,328 --> 02:24:19,163 WAS EXPRESSED WAS SOME 3628 02:24:19,163 --> 02:24:21,032 FRUSTRATION THAT THERE WAS NO 3629 02:24:21,032 --> 02:24:23,768 STRAIGHTFORWARD PATH TO ACHIEVE 3630 02:24:23,768 --> 02:24:24,102 THIS. 3631 02:24:24,102 --> 02:24:28,272 SO, THE DEVELOPMENT OF AN OFFICE 3632 02:24:28,272 --> 02:24:30,908 THAT CAN FACILITATE 3633 02:24:30,908 --> 02:24:33,311 COLLABORATION BETWEEN NIDCR AND 3634 02:24:33,311 --> 02:24:34,679 PROFESSIONAL ORGANIZATIONS MAY 3635 02:24:34,679 --> 02:24:40,084 BE MOST EFFICIENT WAY TO ACHIEVE 3636 02:24:40,084 --> 02:24:40,952 THESE COMMON GOALS. 3637 02:24:40,952 --> 02:24:44,055 SO THERE ARE SEVERAL CHALLENGES 3638 02:24:44,055 --> 02:24:45,223 THAT WERE IDENTIFIED, AND I'M 3639 02:24:45,223 --> 02:24:47,125 GOING TO GO THROUGH SOME OF THEM 3640 02:24:47,125 --> 02:24:49,861 THAT WERE MENTIONED BY TRAINEES. 3641 02:24:49,861 --> 02:24:55,333 AND THESE ARE SIGNIFICANT 3642 02:24:55,333 --> 02:24:56,334 BECAUSE PROFESSIONAL SOCIETIES 3643 02:24:56,334 --> 02:25:00,438 ADDRESS CHALLENGES, ONE IS THAT 3644 02:25:00,438 --> 02:25:01,606 DOC TRAINEES AND EARLY-STAGE 3645 02:25:01,606 --> 02:25:02,573 INVESTIGATORS SOFTEN TELL US 3646 02:25:02,573 --> 02:25:05,443 THEY WERE SILOED AND LACK ROBUST 3647 02:25:05,443 --> 02:25:07,578 RESEARCH COMMUNITY. 3648 02:25:07,578 --> 02:25:09,447 THE TRAINEES WERE OFTEN UNAWARE 3649 02:25:09,447 --> 02:25:11,482 OF THE OPTIONS AND VARIOUS TYPES 3650 02:25:11,482 --> 02:25:14,085 OF CAREERS THAT ARE OPEN TO 3651 02:25:14,085 --> 02:25:14,652 THEM. 3652 02:25:14,652 --> 02:25:17,822 AND THEY ALSO FELT THAT 3653 02:25:17,822 --> 02:25:18,823 PARTICULARLY DURING THE 3654 02:25:18,823 --> 02:25:20,224 TRANSITION TO INDEPENDENCE THERE 3655 02:25:20,224 --> 02:25:26,464 WAS A NEED FOR MENTORING IN 3656 02:25:26,464 --> 02:25:27,999 APPLYING FOR GRANT SUPPORT AND 3657 02:25:27,999 --> 02:25:29,000 PROTECTING THEIR RESEARCH 3658 02:25:29,000 --> 02:25:29,233 CAREERS. 3659 02:25:29,233 --> 02:25:37,175 THEY ALSO FELT THERE WAS A NEED 3660 02:25:37,175 --> 02:25:45,383 TO HAVE PEER MENTORS IN THIS 3661 02:25:45,383 --> 02:25:48,786 TRANSITION TO INDEPENDENCE. 3662 02:25:48,786 --> 02:25:51,856 SO, PROFESSIONAL SOCIETIES COULD 3663 02:25:51,856 --> 02:25:52,390 IMPROVE MENTORING THROUGH 3664 02:25:52,390 --> 02:25:55,326 SEVERAL AVENUES. 3665 02:25:55,326 --> 02:25:58,196 ONE IS TO PROVIDE INCREASE IN 3666 02:25:58,196 --> 02:26:00,264 THE NUMBERS AND TYPES OF MENTORS 3667 02:26:00,264 --> 02:26:03,434 THAT ARE AVAILABLE TO THEM. 3668 02:26:03,434 --> 02:26:04,669 ANOTHER ASPECT COULD BE 3669 02:26:04,669 --> 02:26:06,404 IMPORTANT IS CONNECTION WITH 3670 02:26:06,404 --> 02:26:08,806 ROLE MODELS, AND WHILE ALL OF 3671 02:26:08,806 --> 02:26:09,674 THE TRAINEES FELT IT WAS 3672 02:26:09,674 --> 02:26:12,944 IMPORTANT TO HAVE ROLE MODELS, 3673 02:26:12,944 --> 02:26:15,379 THE CLINICIAN SCIENTISTS AND 3674 02:26:15,379 --> 02:26:17,014 MEMBERS OF UNDERREPRESENTED 3675 02:26:17,014 --> 02:26:18,015 COMMUNITIES FELT THEY WERE IN 3676 02:26:18,015 --> 02:26:19,617 PARTICULAR IN FEED FOR ROLE 3677 02:26:19,617 --> 02:26:21,285 MODELS BECAUSE THEY FELT 3678 02:26:21,285 --> 02:26:23,888 SOMEWHAT ISOLATED IN DENTAL 3679 02:26:23,888 --> 02:26:24,989 SCHOOL ENVIRONMENTS. 3680 02:26:24,989 --> 02:26:27,058 ANOTHER ASPECT OF THIS IS THERE 3681 02:26:27,058 --> 02:26:29,360 HAS BEEN A VERY SUCCESSFUL 3682 02:26:29,360 --> 02:26:33,231 PROGRAM WHICH ALL OF YOU ARE 3683 02:26:33,231 --> 02:26:38,035 AWARE OF CALLED MIND THE FUTURE 3684 02:26:38,035 --> 02:26:39,303 EFFECTIVE IN ENHANCING 3685 02:26:39,303 --> 02:26:40,538 MENTORING, DEVELOPING NETWORK 3686 02:26:40,538 --> 02:26:48,646 OPPORTUNITIES, AND IN BUILDING 3687 02:26:48,646 --> 02:26:53,551 ROBUST RESEARCH COMMUNITIES. 3688 02:26:53,551 --> 02:26:56,621 THE COLLABORATIONS WITH 3689 02:26:56,621 --> 02:26:58,189 PROFESSIONAL SOCIETIES CAN ALSO 3690 02:26:58,189 --> 02:27:01,225 BENEFIT CREATION OF DOC 3691 02:27:01,225 --> 02:27:03,594 NETWORKS, AND THESE NETWORKS MAY 3692 02:27:03,594 --> 02:27:05,496 BE IMPORTANT BECAUSE THEY CAN 3693 02:27:05,496 --> 02:27:07,465 TAKE DENTAL SCHOOLS THAT DON'T 3694 02:27:07,465 --> 02:27:08,566 HAVE A RICH RESEARCH 3695 02:27:08,566 --> 02:27:11,502 INFRASTRUCTURE AND HELP LINK 3696 02:27:11,502 --> 02:27:14,238 THEM WITH THE SCHOOLS THAT DO, 3697 02:27:14,238 --> 02:27:18,176 AND THEY CAN HELP DEVELOP 3698 02:27:18,176 --> 02:27:19,510 PROGRAMS JOINTLY WITH 3699 02:27:19,510 --> 02:27:20,578 PROFESSIONAL SOCIETIES. 3700 02:27:20,578 --> 02:27:22,113 IN ADDITION TO COLLABORATION 3701 02:27:22,113 --> 02:27:26,817 BETWEEN ORAL HEALTH AND NIDCR 3702 02:27:26,817 --> 02:27:28,119 TRAINING PROGRAMS, ESPECIALLY AS 3703 02:27:28,119 --> 02:27:32,089 THEY INVOLVE INDUSTRY, COULD 3704 02:27:32,089 --> 02:27:34,258 HELP DEVELOPMENT OF 3705 02:27:34,258 --> 02:27:35,459 ENTREPRENEURSHIP AND THE 3706 02:27:35,459 --> 02:27:37,295 EXPOSURE OF TRAINEES TO THIS 3707 02:27:37,295 --> 02:27:47,638 TYPE OF ENVIRONMENT. 3708 02:27:52,076 --> 02:27:54,178 COLLABORATIONS WITH INDUSTRY 3709 02:27:54,178 --> 02:28:02,386 COULD EMBED DOC TRAINEES TO 3710 02:28:02,386 --> 02:28:03,721 EXPOSE THEM TO PRODUCT 3711 02:28:03,721 --> 02:28:05,022 DEVELOPMENT, COULD COLLABORATE 3712 02:28:05,022 --> 02:28:07,225 TO DEVELOP NEW RESEARCH 3713 02:28:07,225 --> 02:28:08,292 OPPORTUNITIES FOR CLINICIANS AND 3714 02:28:08,292 --> 02:28:10,728 THERE CAN BE SOME CREATIVITY IN 3715 02:28:10,728 --> 02:28:14,232 THIS FIELD TO DEVELOP NEW 3716 02:28:14,232 --> 02:28:15,399 PROGRAMS THAT DON'T NECESSARILY 3717 02:28:15,399 --> 02:28:17,935 INCLUDE A Ph.D. PROGRAM. 3718 02:28:17,935 --> 02:28:21,305 AND THEN NIDCR AND DENTAL 3719 02:28:21,305 --> 02:28:24,041 SCHOOLS COULD DEVELOP HYBRID 3720 02:28:24,041 --> 02:28:25,943 FACULTY POSITIONS THAT COMBINE 3721 02:28:25,943 --> 02:28:27,812 CLINICAL TEACHING AND 3722 02:28:27,812 --> 02:28:29,647 SUBSTANTIAL CLINICAL RESEARCH. 3723 02:28:29,647 --> 02:28:32,450 AND THIS IS PROBABLY NECESSARY 3724 02:28:32,450 --> 02:28:34,585 BECAUSE DENTAL SCHOOLS DON'T 3725 02:28:34,585 --> 02:28:37,955 HAVE THE CAPACITY TO HIRE LARGE 3726 02:28:37,955 --> 02:28:41,959 NUMBERS OF TENURE TRACK FACULTY 3727 02:28:41,959 --> 02:28:43,494 WHO ONLY DO RESEARCH, SO THE 3728 02:28:43,494 --> 02:28:45,363 NEED OF DENTAL SCHOOL IS 3729 02:28:45,363 --> 02:28:47,198 CLINICIANS WHO DO TEACHING AND 3730 02:28:47,198 --> 02:28:50,368 THERE IS A NATURAL WAY OF 3731 02:28:50,368 --> 02:28:51,902 COMBINING CLINICAL TEACHING AND 3732 02:28:51,902 --> 02:28:59,944 CLINICAL RESEARCH SO NEW HYBRID 3733 02:28:59,944 --> 02:29:02,313 FACULTY POSITIONS COULD BE 3734 02:29:02,313 --> 02:29:02,580 DEVELOPED. 3735 02:29:02,580 --> 02:29:04,382 HARVARD HAS GONE DOWN THIS PATH, 3736 02:29:04,382 --> 02:29:12,256 A WAY OF COMBINING BOTH 3737 02:29:12,256 --> 02:29:13,157 ACTIVITIES. 3738 02:29:13,157 --> 02:29:13,724 PROFESSIONAL SOCIETIES HAVE 3739 02:29:13,724 --> 02:29:15,559 EXPRESSED A LOT OF ENTHUSIASM 3740 02:29:15,559 --> 02:29:17,862 FOR WORKING WITH NIDCR ON COMMON 3741 02:29:17,862 --> 02:29:20,031 GOALS, AND I'M GOING TO GO 3742 02:29:20,031 --> 02:29:22,767 THROUGH A LIST OF SOME OF THESE 3743 02:29:22,767 --> 02:29:24,735 SPECIFIC COLLABORATIONS THAT 3744 02:29:24,735 --> 02:29:26,470 THEY HAVE DISCUSSED. 3745 02:29:26,470 --> 02:29:28,239 THEY INCLUDE PROVIDING SUPPORT 3746 02:29:28,239 --> 02:29:30,875 FOR RESEARCH MEETINGS THAT BRING 3747 02:29:30,875 --> 02:29:34,178 VARIOUS GROUPS TOGETHER. 3748 02:29:34,178 --> 02:29:35,479 TO ESTABLISH NATIONAL, REGIONAL, 3749 02:29:35,479 --> 02:29:37,982 AND LOCAL COLLABORATIONS TO 3750 02:29:37,982 --> 02:29:41,686 STRENGTHEN ACADEMIC PROGRAMS AND 3751 02:29:41,686 --> 02:29:42,787 INCREASE ACCESSIBILITY TO 3752 02:29:42,787 --> 02:29:44,522 NIDCR-FUNDED TRAINING PROGRAMS. 3753 02:29:44,522 --> 02:29:46,524 TO SUPPORT RESEARCH THROUGH 3754 02:29:46,524 --> 02:29:48,259 GRANTS AND LOAN REPAYMENT 3755 02:29:48,259 --> 02:29:48,793 PROGRAMS. 3756 02:29:48,793 --> 02:29:52,096 PROVIDE FINANCIAL SUPPORT FOR 3757 02:29:52,096 --> 02:29:53,597 TRAVEL SCHOLARSHIPS INCLUDING 3758 02:29:53,597 --> 02:29:56,367 THOSE TO NIDCR EVENTS, AND TO 3759 02:29:56,367 --> 02:29:59,437 DEVELOP MATCHING PROGRAMS TO 3760 02:29:59,437 --> 02:30:00,604 SUPPORT NIDCR-FUNDED JUNIOR 3761 02:30:00,604 --> 02:30:01,105 FACULTY. 3762 02:30:01,105 --> 02:30:03,474 AND THE LATTER MAY BE 3763 02:30:03,474 --> 02:30:05,576 SIGNIFICANT BECAUSE K AWARDS ARE 3764 02:30:05,576 --> 02:30:08,412 VERY IMPORTANT AND QUITE 3765 02:30:08,412 --> 02:30:10,614 SUCCESSFUL IN DEVELOPING JUNIOR 3766 02:30:10,614 --> 02:30:12,350 INVESTIGATORS BUT THEY DON'T 3767 02:30:12,350 --> 02:30:14,251 HAVE SIGNIFICANT AMOUNT OF 3768 02:30:14,251 --> 02:30:17,922 RESEARCH FUNDING, AND THERE ARE 3769 02:30:17,922 --> 02:30:24,095 PROGRAMS WHO SUPPORT K-FUNDED 3770 02:30:24,095 --> 02:30:30,434 SCHOLARS. 3771 02:30:30,434 --> 02:30:32,837 WE HIT OUR FIRST TECHNICAL 3772 02:30:32,837 --> 02:30:36,907 GLITCH BUT WE'RE BACK ON PATH. 3773 02:30:36,907 --> 02:30:41,278 THERE ARE SEVERAL EXAMPLES OF 3774 02:30:41,278 --> 02:30:41,946 NIH COLLABORATING WITH 3775 02:30:41,946 --> 02:30:42,680 PROFESSIONAL SOCIETIES. 3776 02:30:42,680 --> 02:30:45,449 WHEN WE STARTED THINKING ABOUT 3777 02:30:45,449 --> 02:30:48,586 THIS CONCEPT, I THOUGHT THIS WAS 3778 02:30:48,586 --> 02:30:50,020 PERHAPS A RARE EVENT, BUT 3779 02:30:50,020 --> 02:30:53,090 THERE'S A STANDING NUMBER OF 3780 02:30:53,090 --> 02:30:53,924 COLLABORATIONS WITH PROFESSIONAL 3781 02:30:53,924 --> 02:30:55,159 SOCIETIES, AND I'M GOING TO GO 3782 02:30:55,159 --> 02:30:57,027 THROUGH A FEW OF THEM NOW. 3783 02:30:57,027 --> 02:30:59,330 ONE OF THEM IS THE "ALL OF US" 3784 02:30:59,330 --> 02:31:01,966 RESEARCH PROGRAM WHICH IS THE 3785 02:31:01,966 --> 02:31:04,435 COLLABORATION BETWEEN NIH AND 3786 02:31:04,435 --> 02:31:08,606 MEDICAL SOCIETIES, TO BUILD A 3787 02:31:08,606 --> 02:31:09,073 HEALTH DATABASE. 3788 02:31:09,073 --> 02:31:12,109 THERE'S THE R25 PROGRAM, IN 3789 02:31:12,109 --> 02:31:13,978 WHICH PROFESSIONAL SOCIETIES 3790 02:31:13,978 --> 02:31:15,179 CONTRIBUTE TO DEVELOPING 3791 02:31:15,179 --> 02:31:22,153 EDUCATIONAL PROGRAMS TO RECRUIT 3792 02:31:22,153 --> 02:31:25,122 JUNIOR FACULTY FROM DIFFERENT 3793 02:31:25,122 --> 02:31:25,689 BACKGROUNDS. 3794 02:31:25,689 --> 02:31:27,558 AND NIDA PARTNERED WITH 3795 02:31:27,558 --> 02:31:28,759 PROFESSIONAL SOCIETIES TO 3796 02:31:28,759 --> 02:31:30,861 DEVELOP PROGRAMS TO TRAIN 3797 02:31:30,861 --> 02:31:34,131 CLINICIANS IN BEST PRACTICES. 3798 02:31:34,131 --> 02:31:38,702 THE NATIONAL CANCER CENTER HAS 3799 02:31:38,702 --> 02:31:39,904 SEVERAL COLLABORATIONS WITH 3800 02:31:39,904 --> 02:31:43,507 PROFESSIONAL SOCIETIES TO BRING 3801 02:31:43,507 --> 02:31:44,742 FUNDING AND TRAINING PROGRAMS. 3802 02:31:44,742 --> 02:31:49,447 ONE OF THEM IS A PROGRAM TO 3803 02:31:49,447 --> 02:31:51,949 DEVELOP NOVEL FUNDING 3804 02:31:51,949 --> 02:31:55,553 MECHANISMS, AND ANOTHER IS TO 3805 02:31:55,553 --> 02:31:56,754 INTRODUCE ARTIFICIAL 3806 02:31:56,754 --> 02:32:01,358 INTELLIGENCE TO CANCER RESEARCH. 3807 02:32:01,358 --> 02:32:03,427 THE JUVENILE DIABETES RESEARCH 3808 02:32:03,427 --> 02:32:07,998 FOUNDATION NIDCR COLLABORATE TO 3809 02:32:07,998 --> 02:32:08,566 PROMOTE INTERDISCIPLINARY 3810 02:32:08,566 --> 02:32:10,167 WORKSHOPS, AND NINDS 3811 02:32:10,167 --> 02:32:14,505 COLLABORATES WITH PROFESSIONAL 3812 02:32:14,505 --> 02:32:15,706 SOCIETIES TO DEVELOP BEST 3813 02:32:15,706 --> 02:32:16,674 CLINICAL PRACTICES. 3814 02:32:16,674 --> 02:32:19,844 I'M GOING TO TRANSITION NOW TO 3815 02:32:19,844 --> 02:32:23,881 THE SECOND OFFICE THAT I HAD 3816 02:32:23,881 --> 02:32:25,549 MENTIONED, AND I HAD AN 3817 02:32:25,549 --> 02:32:26,450 ARTIFICIAL INTELLIGENCE PROGRAM 3818 02:32:26,450 --> 02:32:28,953 THAT I ASKED TO RECOMMEND A 3819 02:32:28,953 --> 02:32:30,788 CARTOON THAT WOULD BE HUMOROUS 3820 02:32:30,788 --> 02:32:31,789 TO DENTAL RESEARCHERS. 3821 02:32:31,789 --> 02:32:39,763 AND THIS IS THE ONE THEY CAME UP 3822 02:32:39,763 --> 02:32:40,331 WITH. 3823 02:32:40,331 --> 02:32:42,633 SO, THE SECOND OFFICE THAT WE'VE 3824 02:32:42,633 --> 02:32:45,503 BEEN THINKING ABOUT IS INVOLVED 3825 02:32:45,503 --> 02:32:46,871 IN TRAINING PROGRAM ASSESSMENT. 3826 02:32:46,871 --> 02:32:51,509 AND THERE ARE A NUMBER OF ISSUES 3827 02:32:51,509 --> 02:32:53,244 RELATED TO TRAINING PROGRAMS 3828 02:32:53,244 --> 02:32:54,912 THAT MAKE THEM DIFFICULT TO 3829 02:32:54,912 --> 02:32:55,412 ASSESS. 3830 02:32:55,412 --> 02:33:00,284 ONE OF THEM IS THAT THE 3831 02:33:00,284 --> 02:33:03,754 SELF-ASSESSMENT IS OFTEN 3832 02:33:03,754 --> 02:33:04,054 PROBLEMATIC. 3833 02:33:04,054 --> 02:33:06,790 THERE IS LITTLE ACTUAL DATA ON 3834 02:33:06,790 --> 02:33:08,459 THE TRAINEE FACTORS AND TRAINING 3835 02:33:08,459 --> 02:33:11,629 PROGRAM FACTORS THAT LEAD TO 3836 02:33:11,629 --> 02:33:11,929 SUCCESS. 3837 02:33:11,929 --> 02:33:15,132 AND THERE IS A LACK OF DATA ON 3838 02:33:15,132 --> 02:33:18,302 THE NUMBER OF TRAINEES THAT ARE 3839 02:33:18,302 --> 02:33:20,170 NEEDED FOR CURRENT POSITIONS OR 3840 02:33:20,170 --> 02:33:23,340 FUTURE RESEARCH NEEDS. 3841 02:33:23,340 --> 02:33:25,409 AND ALSO IT'S UNKNOWN WHETHER 3842 02:33:25,409 --> 02:33:27,811 THERE ARE SPECIFIC AREAS THAT 3843 02:33:27,811 --> 02:33:31,115 RESEARCH TRAINING SHOULD BE 3844 02:33:31,115 --> 02:33:31,882 TARGETED TOWARD. 3845 02:33:31,882 --> 02:33:36,153 SO THERE ARE SEVERAL COMMENTS 3846 02:33:36,153 --> 02:33:38,455 FROM STAKEHOLDERS ABOUT THE 3847 02:33:38,455 --> 02:33:39,323 ASSESSMENT OF TRAINING PROGRAMS, 3848 02:33:39,323 --> 02:33:40,958 AND THEY ARE SHOWN HERE. 3849 02:33:40,958 --> 02:33:44,128 THIS IS JUST A COLLECTION OF 3850 02:33:44,128 --> 02:33:45,262 ONES THAT WERE SIGNIFICANT, 3851 02:33:45,262 --> 02:33:47,965 ALTHOUGH THERE ARE MANY OTHERS. 3852 02:33:47,965 --> 02:33:50,834 THERE'S A NEED TO ENHANCE 3853 02:33:50,834 --> 02:33:53,771 COLLECTION OF DATA AND DEEPER 3854 02:33:53,771 --> 02:33:56,674 ANALYSIS OF TRAINING PROGRAMS, 3855 02:33:56,674 --> 02:33:59,143 AND TO USE DATA MINING OF 3856 02:33:59,143 --> 02:34:01,879 DATABASES TO BETTER UNDERSTAND 3857 02:34:01,879 --> 02:34:04,048 WHAT LEADS TO SUCCESS. 3858 02:34:04,048 --> 02:34:06,150 THERE'S ALSO AN IMPORTANT ISSUE 3859 02:34:06,150 --> 02:34:09,753 WHICH IS THE MINORITY OF DEGREE 3860 02:34:09,753 --> 02:34:10,721 TRAINEES ACTUALLY GO INTO 3861 02:34:10,721 --> 02:34:12,022 RESEARCH INTENSIVE CAREERS, BUT 3862 02:34:12,022 --> 02:34:14,558 IT'S NOT KNOWN IF THIS IS 3863 02:34:14,558 --> 02:34:16,627 REASONABLE OR NOT REASONABLE. 3864 02:34:16,627 --> 02:34:19,263 SO MAYBE THIS IS THE BEST THAT 3865 02:34:19,263 --> 02:34:21,365 CAN BE EXPECTED, OR MAYBE IT 3866 02:34:21,365 --> 02:34:23,300 FALLS SHORT, AND THERE NEEDS TO 3867 02:34:23,300 --> 02:34:28,439 BE CHANGES IN THE WAY TRAINEES 3868 02:34:28,439 --> 02:34:29,006 UNDERGO THESE PROGRAMS. 3869 02:34:29,006 --> 02:34:33,711 AND THERE HAS BEEN A QUESTION IS 3870 02:34:33,711 --> 02:34:38,315 THERE AN ACTUAL DECLINE IN 3871 02:34:38,315 --> 02:34:38,882 DENTIST-SCIENTIST RESEARCH 3872 02:34:38,882 --> 02:34:41,051 WORKFORCE, AND IF IT'S A 3873 02:34:41,051 --> 02:34:42,786 SIGNIFICANT PROBLEM. 3874 02:34:42,786 --> 02:34:45,389 THERE'S-- YOU CAN THINK OF THIS 3875 02:34:45,389 --> 02:34:48,993 ANOTHER WAY, IS WHAT PERCENTAGE 3876 02:34:48,993 --> 02:34:53,097 OF DENTAL RESEARCHERS SHOULD 3877 02:34:53,097 --> 02:34:54,932 HAVE A CLINICAL DEGREE. 3878 02:34:54,932 --> 02:34:57,768 OTHER QUESTIONS ARE WHAT TYPE OF 3879 02:34:57,768 --> 02:35:01,605 MENTORING PROGRAMS LEAD TO 3880 02:35:01,605 --> 02:35:05,776 SUCCESS, HAVE MENTORS AND 3881 02:35:05,776 --> 02:35:06,777 MENTEES SOCIETY GOALS, GUIDING 3882 02:35:06,777 --> 02:35:12,583 TO CAREER PATH, IS THERE A NEED 3883 02:35:12,583 --> 02:35:13,784 FOR MULTI-MENTORS OR MENTORING 3884 02:35:13,784 --> 02:35:14,184 TEAMS? 3885 02:35:14,184 --> 02:35:15,519 THIS IS SIGNIFICANT SINCE THE 3886 02:35:15,519 --> 02:35:16,954 QUESTION OF MENTORING WAS 3887 02:35:16,954 --> 02:35:21,859 BROUGHT UP MANY TIMES BY 3888 02:35:21,859 --> 02:35:22,326 TRAINEES. 3889 02:35:22,326 --> 02:35:23,293 THERE'S SOME BROADER QUESTIONS 3890 02:35:23,293 --> 02:35:26,730 SUCH AS WHAT IS THE LENGTH OF 3891 02:35:26,730 --> 02:35:29,566 TIME AND TRAINING THAT IS NEEDED 3892 02:35:29,566 --> 02:35:34,738 TO TRAIN A DOC RESEARCHER. 3893 02:35:34,738 --> 02:35:36,607 THE TRAINEE FELT THE TIME WAS 3894 02:35:36,607 --> 02:35:39,376 TOO LONG AND TRAINING PERIOD WAS 3895 02:35:39,376 --> 02:35:40,210 TOO EXTENSIVE. 3896 02:35:40,210 --> 02:35:42,713 WHAT TYPE OF ACADEMIC PHYSICIANS 3897 02:35:42,713 --> 02:35:45,115 CAN BE CREATED THAT WILL GIVE A 3898 02:35:45,115 --> 02:35:46,450 SUBSTANTIAL AMOUNT OF PROTECTED 3899 02:35:46,450 --> 02:35:47,718 TIME FOR RESEARCH? 3900 02:35:47,718 --> 02:35:51,388 AND WHAT IS THIS AMOUNT OF TIME 3901 02:35:51,388 --> 02:35:51,722 THAT'S NEEDED? 3902 02:35:51,722 --> 02:35:54,224 MAYBE THE TIME FOR THOSE DOING 3903 02:35:54,224 --> 02:35:55,626 CLINICAL RESEARCH IS NOT THE 3904 02:35:55,626 --> 02:35:57,561 SAME AS THOSE DOING BASIC 3905 02:35:57,561 --> 02:35:59,430 RESEARCH, OR MAYBE THEY ARE THE 3906 02:35:59,430 --> 02:36:01,331 SAME, BUT THIS IS THE QUESTION 3907 02:36:01,331 --> 02:36:02,966 THAT SHOULD BE ADDRESSED. 3908 02:36:02,966 --> 02:36:05,502 AND THEN THERE'S THE ISSUE ABOUT 3909 02:36:05,502 --> 02:36:09,873 HOW DO YOU ALIGN THE 3910 02:36:09,873 --> 02:36:12,543 EXPECTATIONS FROM NIDCR OR FROM 3911 02:36:12,543 --> 02:36:17,981 THE CLINICIANS THEMSELVES FOR 3912 02:36:17,981 --> 02:36:18,982 CLINICIAN-SCIENTISTS AND CAREER 3913 02:36:18,982 --> 02:36:20,617 PATHS AVAILABLE TO THEM, DEALING 3914 02:36:20,617 --> 02:36:22,686 WITH ISSUES DENTAL SCHOOLS HAVE 3915 02:36:22,686 --> 02:36:25,556 LOTS OF OPENINGS FOR CLINICAL 3916 02:36:25,556 --> 02:36:28,625 TEACHERS BUT DON'T HAVE A LOT OF 3917 02:36:28,625 --> 02:36:32,129 OPENINGS THAT ARE STRICTLY BASED 3918 02:36:32,129 --> 02:36:34,198 ON DOING RESEARCH. 3919 02:36:34,198 --> 02:36:36,400 SO, A CENTRAL COORDINATION 3920 02:36:36,400 --> 02:36:41,739 CENTER IS NEEDED TO IDENTIFY KEY 3921 02:36:41,739 --> 02:36:43,941 TRAINING AND FACTORS THAT LEAD 3922 02:36:43,941 --> 02:36:45,476 TO SUCCESS. 3923 02:36:45,476 --> 02:36:47,344 SUCH AN OFFICE COULD ESTABLISH 3924 02:36:47,344 --> 02:36:48,212 MEASURES AND INTEGRATE OUTCOME 3925 02:36:48,212 --> 02:36:53,684 MEASURES WITH WHAT IS NEEDED FOR 3926 02:36:53,684 --> 02:36:54,918 THE DOC WORKFORCE. 3927 02:36:54,918 --> 02:36:58,288 AND AN OFFICE FOR EVALUATION OF 3928 02:36:58,288 --> 02:36:59,156 TRAINING OUTCOMES AND 3929 02:36:59,156 --> 02:37:01,125 INITIATIVES TO LEAD TO 3930 02:37:01,125 --> 02:37:03,427 DEVELOPMENT OF WELL-DEFINED 3931 02:37:03,427 --> 02:37:05,863 METRICS TO EVALUATE TRAINEES AND 3932 02:37:05,863 --> 02:37:07,931 MENTORS, AND TRAINING PROGRAM 3933 02:37:07,931 --> 02:37:11,335 OUTCOMES, AND THIS COULD ENHANCE 3934 02:37:11,335 --> 02:37:12,736 TRAINING ENGAGEMENT AND MODIFY 3935 02:37:12,736 --> 02:37:16,573 APPROACHES NEEDED TO INCREASE 3936 02:37:16,573 --> 02:37:20,177 THE OVERALL IMPACT. 3937 02:37:20,177 --> 02:37:22,379 AND LASTLY, I'M GOING TO THROW 3938 02:37:22,379 --> 02:37:25,415 SOMETHING OUT ON THE TABLE WHICH 3939 02:37:25,415 --> 02:37:28,252 MAY BE FOOD FOR THOUGHT, BUT ONE 3940 02:37:28,252 --> 02:37:30,888 OF THE WAYS TO ESTABLISH SUCH AN 3941 02:37:30,888 --> 02:37:36,160 OFFICE COULD BE THROUGH A 3942 02:37:36,160 --> 02:37:37,594 P30-TYPE COMPETITIVE RESEARCH 3943 02:37:37,594 --> 02:37:39,463 DENTAL PROGRAM IN WHICH THE 3944 02:37:39,463 --> 02:37:42,099 OFFICE IS NOT NECESSARILY 3945 02:37:42,099 --> 02:37:45,736 EMBEDDED IN ONE ACADEMIC CENTER 3946 02:37:45,736 --> 02:37:47,704 OR EMBEDDED INTO NIDCR BUT COULD 3947 02:37:47,704 --> 02:37:50,440 BE THOUGHT OF AS SOMETHING THAT 3948 02:37:50,440 --> 02:37:52,509 IS REVIEWED AND DONE 3949 02:37:52,509 --> 02:37:55,579 COMPETITIVELY SO THAT THE MOST 3950 02:37:55,579 --> 02:37:57,114 EFFECTIVE TYPES OF 3951 02:37:57,114 --> 02:37:58,949 COLLABORATIONS COULD OCCUR THAT 3952 02:37:58,949 --> 02:38:02,186 WOULD LEAD TO AN EFFECTIVE 3953 02:38:02,186 --> 02:38:03,487 ASSESSMENT OUTCOMES OFFICE. 3954 02:38:03,487 --> 02:38:05,322 SO WITH THAT I'D LIKE TO THANK 3955 02:38:05,322 --> 02:38:06,523 YOU AND ANSWER ANY QUESTIONS YOU 3956 02:38:06,523 --> 02:38:14,097 MIGHT HAVE. 3957 02:38:14,097 --> 02:38:16,033 >> THANK YOU, DANE A DOES 3958 02:38:16,033 --> 02:38:18,101 ANYBODY HAVE ANY QUESTIONS OR 3959 02:38:18,101 --> 02:38:18,368 COMMENTS? 3960 02:38:18,368 --> 02:38:28,846 >> WE NEED OUR VIDEOS ON, IF 3961 02:38:29,046 --> 02:38:29,246 POSSIBLE. 3962 02:38:29,246 --> 02:38:29,847 >> YEAH. 3963 02:38:29,847 --> 02:38:31,348 >> SO, THANK YOU, DANA. 3964 02:38:31,348 --> 02:38:32,749 THIS IS TERRIFIC. 3965 02:38:32,749 --> 02:38:35,519 TERRIFIC WORK THAT YOU AND YOUR 3966 02:38:35,519 --> 02:38:37,454 TEAM HAVE DONE. 3967 02:38:37,454 --> 02:38:40,524 I WAS WONDERING ABOUT THE HYBRID 3968 02:38:40,524 --> 02:38:41,592 FACULTY POSITIONS. 3969 02:38:41,592 --> 02:38:43,694 CAN YOU EXPAND A LITTLE BIT MORE 3970 02:38:43,694 --> 02:38:45,462 ON THAT BECAUSE I DIDN'T QUITE 3971 02:38:45,462 --> 02:38:47,531 UNDERSTAND YOUR TALK ABOUT 3972 02:38:47,531 --> 02:38:52,569 CLINICAL RESEARCH WITHIN FACULTY 3973 02:38:52,569 --> 02:38:54,438 POSITIONS AND THEN THE SITE 3974 02:38:54,438 --> 02:38:57,274 HARVARD IS ALREADY DOING 3975 02:38:57,274 --> 02:38:58,275 SOMETHING ALONG THOSE LINES, CAN 3976 02:38:58,275 --> 02:39:01,979 YOU EXPAND MORE ON HOW THIS 3977 02:39:01,979 --> 02:39:06,450 HYBRID FACULTY POSITION WOULD 3978 02:39:06,450 --> 02:39:08,952 LOOK LIKE? 3979 02:39:08,952 --> 02:39:09,286 >> SURE. 3980 02:39:09,286 --> 02:39:10,621 THE TYPICAL -- THE CLINICAL 3981 02:39:10,621 --> 02:39:11,822 FACULTY POSITION AT THE 3982 02:39:11,822 --> 02:39:13,690 UNIVERSITY OF PENNSYLVANIA, AND 3983 02:39:13,690 --> 02:39:17,394 I THINK AT MOST UNIVERSITIES OR 3984 02:39:17,394 --> 02:39:19,930 DENTAL SCHOOLS, IS A TENURE 3985 02:39:19,930 --> 02:39:21,265 TRACK POSITION WHERE THE FACULTY 3986 02:39:21,265 --> 02:39:24,668 MEMBER DOES RESEARCH FOUR DAYS A 3987 02:39:24,668 --> 02:39:35,212 WEEK, AND DOES ADMINISTRATION OR 3988 02:39:36,313 --> 02:39:37,681 DIDACTIC THE OTHER DAY A WEEK. 3989 02:39:37,681 --> 02:39:39,216 THE OTHER IS RESEARCH ONE DAY A 3990 02:39:39,216 --> 02:39:42,619 WEEK, THE PROBLEM IS ONE DAY A 3991 02:39:42,619 --> 02:39:45,489 WEEK IS PROBABLY NOT ENOUGH TO 3992 02:39:45,489 --> 02:39:47,557 HAVE A ROBUST RESEARCH CAREER. 3993 02:39:47,557 --> 02:39:51,061 AND FOUR DAYS A WEEK IS JUST TOO 3994 02:39:51,061 --> 02:39:51,328 EXPENSIVE. 3995 02:39:51,328 --> 02:39:53,997 YOU CAN ONLY HAVE SO MANY FOUR 3996 02:39:53,997 --> 02:39:55,866 DAYS A WEEK RESEARCH POSITIONS 3997 02:39:55,866 --> 02:40:00,170 BECAUSE IT'S VERY EXPENSIVE FOR 3998 02:40:00,170 --> 02:40:01,905 THE SCHOOLS. 3999 02:40:01,905 --> 02:40:03,774 AND IN FACT, YOU'RE LUCKY IF 4000 02:40:03,774 --> 02:40:05,742 YOU'RE A SCHOOL WITH A 4001 02:40:05,742 --> 02:40:08,045 RESEARCHER THAT CAN COVER 50% OF 4002 02:40:08,045 --> 02:40:09,146 THEIR SALARY THROUGH GRANT 4003 02:40:09,146 --> 02:40:09,479 SUPPORT. 4004 02:40:09,479 --> 02:40:12,649 SO YOU COULD THINK OF HAVING A 4005 02:40:12,649 --> 02:40:14,785 HYBRID POSITION FOR AN 4006 02:40:14,785 --> 02:40:16,586 INDIVIDUAL TWO DAYS A WEEK OF 4007 02:40:16,586 --> 02:40:18,989 RESEARCH OR THREE DAYS A WEEK OF 4008 02:40:18,989 --> 02:40:20,190 RESEARCH, BUT IT'S IN BETWEEN. 4009 02:40:20,190 --> 02:40:22,626 THAT'S WHY I CALL IT HYBRID 4010 02:40:22,626 --> 02:40:24,461 BECAUSE IT'S SORT OF IN BETWEEN 4011 02:40:24,461 --> 02:40:31,568 THE TWO CLASSIC POSITIONS THAT 4012 02:40:31,568 --> 02:40:32,803 CURRENTLY EXIST. 4013 02:40:32,803 --> 02:40:35,105 THIS WOULD REDUCE COST FOR 4014 02:40:35,105 --> 02:40:36,840 DENTAL SCHOOLS, BUT INCREASE 4015 02:40:36,840 --> 02:40:38,475 AMOUNT OF RESEARCH TIME SO THAT 4016 02:40:38,475 --> 02:40:40,444 YOU CAN ACCOMPLISH MORE THAN YOU 4017 02:40:40,444 --> 02:40:43,447 CAN DO ONE DAY A WEEK. 4018 02:40:43,447 --> 02:40:45,949 >> OKAY. 4019 02:40:45,949 --> 02:40:46,283 THANK YOU. 4020 02:40:46,283 --> 02:40:49,319 >> AND IF I COULD ADD ONE MORE 4021 02:40:49,319 --> 02:40:51,321 THOUGHT TO THIS, I THINK NIDCR 4022 02:40:51,321 --> 02:40:54,257 COULD PLAY A VERY IMPORTANT ROLE 4023 02:40:54,257 --> 02:40:56,560 BY HAVING AN RFA THAT WAS 4024 02:40:56,560 --> 02:41:00,831 SPECIFICALLY DESIGNED FOR THIS 4025 02:41:00,831 --> 02:41:03,367 TYPE OF CONCEPT, AND IT GOES 4026 02:41:03,367 --> 02:41:05,335 ALONG WITH THE BASEBALL MOVIE, 4027 02:41:05,335 --> 02:41:09,373 IF YOU BUILD IT, THEY WILL COME. 4028 02:41:09,373 --> 02:41:11,008 SO, IF YOU FUND IT, THEY WILL 4029 02:41:11,008 --> 02:41:17,014 COME, WOULD BE THE COROLLARY TO 4030 02:41:17,014 --> 02:41:17,214 THAT. 4031 02:41:17,214 --> 02:41:21,852 >> JUST QUICK, THANK YOU, DANA. 4032 02:41:21,852 --> 02:41:24,221 I WANTED TO -- LET'S SAY WE 4033 02:41:24,221 --> 02:41:28,425 BUILT AN RFA FOR A PERSON WHO IS 4034 02:41:28,425 --> 02:41:32,562 WANTING TO SPECIALIZE AND DO 4035 02:41:32,562 --> 02:41:33,764 RESEARCH, WHERE THEY WOULD 4036 02:41:33,764 --> 02:41:38,035 HAVE -- WITH A COMPANY OR 4037 02:41:38,035 --> 02:41:39,336 INDUSTRY PARTNER, OR 4038 02:41:39,336 --> 02:41:41,104 PROFESSIONAL SOCIETY WOULD COVER 4039 02:41:41,104 --> 02:41:45,909 CLINICAL TRAINING, AND THEN 4040 02:41:45,909 --> 02:41:47,878 NIDCR WOULD COVER COST OF THEIR 4041 02:41:47,878 --> 02:41:48,311 Ph.D. 4042 02:41:48,311 --> 02:41:51,515 IS THAT ALIGNED WITH WHAT YOU'RE 4043 02:41:51,515 --> 02:41:52,049 THINKING? 4044 02:41:52,049 --> 02:41:55,986 THE SECOND QUESTION IS, AS YOU 4045 02:41:55,986 --> 02:41:58,822 SURVEY THESE DIFFERENT INDUSTRY 4046 02:41:58,822 --> 02:42:01,124 PARTNERS, LEADERS, AND 4047 02:42:01,124 --> 02:42:03,860 PROFESSIONAL SOCIETIES, WHAT WAS 4048 02:42:03,860 --> 02:42:06,596 THE LEVEL OF SUPPORT FOR 4049 02:42:06,596 --> 02:42:08,899 COVERING CLINICALLY RELATED 4050 02:42:08,899 --> 02:42:13,070 ACTIVITY OR POTENTIAL 4051 02:42:13,070 --> 02:42:13,970 INDUSTRY-RELATED RESEARCH? 4052 02:42:13,970 --> 02:42:17,841 >> YEAH, SO, THE PROFESSIONAL 4053 02:42:17,841 --> 02:42:18,975 SOCIETIES WERE INTERESTED IN 4054 02:42:18,975 --> 02:42:22,012 FUNDING AT THE LEVEL OF 4055 02:42:22,012 --> 02:42:22,345 SUPPLEMENTS. 4056 02:42:22,345 --> 02:42:26,817 SO, FOR EXAMPLE, LET'S SAY YOU 4057 02:42:26,817 --> 02:42:29,886 HAD SOMEBODY WHO IS GOING 4058 02:42:29,886 --> 02:42:31,755 THROUGH A RESIDENCY PROGRAM, 4059 02:42:31,755 --> 02:42:34,758 THEY WOULD BE INTERESTED IN 4060 02:42:34,758 --> 02:42:36,893 FUNDING A SUPPLEMENT TO THE 4061 02:42:36,893 --> 02:42:37,994 RESIDENCY PROGRAM THAT COULD BE 4062 02:42:37,994 --> 02:42:39,629 THOUGHT OF IN TWO WAYS. 4063 02:42:39,629 --> 02:42:43,233 ONE WOULD BE AN ADDITIONAL YEAR 4064 02:42:43,233 --> 02:42:45,335 THAT WOULD PAY FOR A -- LET'S 4065 02:42:45,335 --> 02:42:47,571 SAY A CERTIFICATE IN RESEARCH. 4066 02:42:47,571 --> 02:42:52,909 SO, IF YOU HAVE AN ENDODONTIC 4067 02:42:52,909 --> 02:42:54,377 PROGRAM, MAYBE A SURGERY, 4068 02:42:54,377 --> 02:42:55,979 CLINICAL RESEARCH, HALF A YEAR, 4069 02:42:55,979 --> 02:43:01,852 THIS WOULD NOT -- COULD BE A 4070 02:43:01,852 --> 02:43:03,186 DEGREE PROGRAM OR INDEPENDENT OF 4071 02:43:03,186 --> 02:43:04,387 DEGREE PROGRAM BUT WOULD PROVIDE 4072 02:43:04,387 --> 02:43:05,489 RESEARCH PROGRAM THEY DON'T HAVE 4073 02:43:05,489 --> 02:43:07,357 CURRENTLY SO THAT WAS ONE WAY TO 4074 02:43:07,357 --> 02:43:10,093 DO IT. 4075 02:43:10,093 --> 02:43:15,866 THE OTHER WAY, ANOTHER EXAMPLE 4076 02:43:15,866 --> 02:43:17,767 WAS SOME LOAN REPAYMENT 4077 02:43:17,767 --> 02:43:22,105 PROGRAMS, SO THEY MIGHT PARTNER 4078 02:43:22,105 --> 02:43:24,841 WITH NIDCR, ONE EXAMPLE WOULD BE 4079 02:43:24,841 --> 02:43:28,845 LET'S SAY THEY GOT A K99 K00 4080 02:43:28,845 --> 02:43:33,183 AWARD, THEY ARE A CLINICIAN, 4081 02:43:33,183 --> 02:43:34,584 PROFESSIONAL SOCIETY MIGHT HAVE 4082 02:43:34,584 --> 02:43:36,753 A LOAN REPAYMENT PROGRAM THAT 4083 02:43:36,753 --> 02:43:39,089 WAS TIED TO THAT. 4084 02:43:39,089 --> 02:43:41,691 SO, BUT I SHOULD EMPHASIZE THAT 4085 02:43:41,691 --> 02:43:45,295 WHAT THE FROGSAL SOCIETIES ARE 4086 02:43:45,295 --> 02:43:47,063 LACKING IS A BRIDGE BETWEEN 4087 02:43:47,063 --> 02:43:47,931 THEM -- PROFESSIONAL SOCIETIES 4088 02:43:47,931 --> 02:43:49,132 ARE LACKING IS A BRIDGE BETWEEN 4089 02:43:49,132 --> 02:43:54,371 THEM AND NIDCR, TO HAVE 4090 02:43:54,371 --> 02:43:55,772 DISCUSSIONS WITH. 4091 02:43:55,772 --> 02:44:01,711 THEY NEED THE NAME OF A PERSON 4092 02:44:01,711 --> 02:44:07,350 TO GO TO. 4093 02:44:07,350 --> 02:44:08,385 >> JOSE? 4094 02:44:08,385 --> 02:44:10,153 >> I'M IN THE MEDICAL SCHOOL, 4095 02:44:10,153 --> 02:44:13,290 CLINICAL DEPARTMENT, ONE OF THE 4096 02:44:13,290 --> 02:44:16,793 WAYS WE DO THIS, THE TRAINING 4097 02:44:16,793 --> 02:44:17,594 FOR DEPARTMENT OF ANESTHESIA, 4098 02:44:17,594 --> 02:44:20,864 ONE OF THE WAYS WE DO FOR 4099 02:44:20,864 --> 02:44:28,104 M.D.s OR MD/PHDS TO DO 4100 02:44:28,104 --> 02:44:31,374 RESEARCH WE USE A T32 MECHANISM 4101 02:44:31,374 --> 02:44:33,443 TO BASICALLY COVER WHAT THE TIME 4102 02:44:33,443 --> 02:44:36,079 WE RESEARCH, THE REST OF THE 4103 02:44:36,079 --> 02:44:38,381 TIME THAT WE CLINICAL, 4104 02:44:38,381 --> 02:44:40,016 ADMINISTRATIVE, OR, YOU KNOW, 4105 02:44:40,016 --> 02:44:41,251 LECTURING THAT'S COVERED BY THE 4106 02:44:41,251 --> 02:44:41,818 DEPARTMENT. 4107 02:44:41,818 --> 02:44:43,153 BUT THAT'S A WAY WE HAD TO DO 4108 02:44:43,153 --> 02:44:43,453 THAT. 4109 02:44:43,453 --> 02:44:45,622 I DON'T KNOW IF THAT'S THE CASE, 4110 02:44:45,622 --> 02:44:48,158 I'M NOT FAMILIAR WITH THAT, YOU 4111 02:44:48,158 --> 02:44:49,993 KNOW, FOR DENTAL SCHOOLS BUT 4112 02:44:49,993 --> 02:44:51,761 THAT'S THE WAY MANY MEDICAL 4113 02:44:51,761 --> 02:44:55,799 SCHOOLS ARE DOING THAT. 4114 02:44:55,799 --> 02:44:58,168 YOU KNOW, THE T32 WILL COVER, 4115 02:44:58,168 --> 02:44:59,402 MAYBE THE OVER THE CAP, THE 4116 02:44:59,402 --> 02:45:04,307 DEPARTMENT WILL HAVE TO PAY. 4117 02:45:04,307 --> 02:45:06,142 SOMETIMES WE GET FUNDING FROM 4118 02:45:06,142 --> 02:45:08,578 PHYSICIANS OR SOCIETIES TO COVER 4119 02:45:08,578 --> 02:45:13,817 THAT OVER THE CAP, COVER 4120 02:45:13,817 --> 02:45:14,517 ADDITIONAL EXPENSES NOT COVERED. 4121 02:45:14,517 --> 02:45:17,988 >> THAT'S WHAT I WAS REFERRING 4122 02:45:17,988 --> 02:45:20,323 TO WHEN THE PROFESSIONAL 4123 02:45:20,323 --> 02:45:22,058 SOCIETIES TALK ABOUT 4124 02:45:22,058 --> 02:45:22,392 SUPPLEMENTING. 4125 02:45:22,392 --> 02:45:23,260 >> YEAH. 4126 02:45:23,260 --> 02:45:25,996 >> PROVIDING ADDITIONAL FUNDING 4127 02:45:25,996 --> 02:45:27,631 TO MAKE SOMETHING PRACTICAL. 4128 02:45:27,631 --> 02:45:28,064 >> YEAH. 4129 02:45:28,064 --> 02:45:36,206 >> I THINK YOUR IDEA ABOUT 4130 02:45:36,206 --> 02:45:37,841 T32s LYNN CAN ADDRESS BETTER 4131 02:45:37,841 --> 02:45:39,609 BUT THAT'S THE CREATIVITY 4132 02:45:39,609 --> 02:45:42,145 NEEDED, TO EXPAND WHAT'S COVERED 4133 02:45:42,145 --> 02:45:46,149 UNDER TRAINING PROGRAMS, 4134 02:45:46,149 --> 02:45:46,716 ESPECIALLY FOR 4135 02:45:46,716 --> 02:45:48,218 CLINICIAN-SCIENTISTS, TO BRIDGE 4136 02:45:48,218 --> 02:45:50,220 THESE GAPS THAT EXIST. 4137 02:45:50,220 --> 02:45:51,955 AND I THINK THAT THE PROGRAMS 4138 02:45:51,955 --> 02:45:54,624 ARE SET UP VERY WELL, THEY ARE 4139 02:45:54,624 --> 02:45:55,692 DESIGNED FOR BASIC SCIENTISTS, 4140 02:45:55,692 --> 02:45:59,429 AND I THINK THERE NEEDS TO BE 4141 02:45:59,429 --> 02:46:01,931 THIS CREATIVE REASSESSMENT FOR 4142 02:46:01,931 --> 02:46:02,399 CLINICIAN-SCIENTISTS. 4143 02:46:02,399 --> 02:46:04,134 >> YEAH, AND JUST TO MAKE IT 4144 02:46:04,134 --> 02:46:07,103 CLEAR, THE T32 WE HAVE HERE, 4145 02:46:07,103 --> 02:46:08,505 MANY OTHER DEPARTMENTS IN 4146 02:46:08,505 --> 02:46:10,073 MEDICAL SCHOOL, SUPPORTING BOTH 4147 02:46:10,073 --> 02:46:12,142 CLINICAL AND BASIC RESEARCH. 4148 02:46:12,142 --> 02:46:13,777 JUST RESEARCH IN GENERAL. 4149 02:46:13,777 --> 02:46:15,111 IT CAN BE ALLOCATED, IN A 4150 02:46:15,111 --> 02:46:17,180 CLINICAL LAB OR IN A BASIC 4151 02:46:17,180 --> 02:46:17,781 RESEARCH. 4152 02:46:17,781 --> 02:46:25,488 THE OTHER THING WE ACTUALLY HAD 4153 02:46:25,488 --> 02:46:28,124 TO DO TO INCENTIVATE THIS, THEY 4154 02:46:28,124 --> 02:46:29,326 WILL HAVE RESIDENCY FELLOWSHIP 4155 02:46:29,326 --> 02:46:34,030 AND HAVE TO SPEND TWO YEARS ON 4156 02:46:34,030 --> 02:46:35,565 T32, THAN TO GO INTO CLINICAL 4157 02:46:35,565 --> 02:46:36,466 PRACTICE AND MAKE MORE MONEY, 4158 02:46:36,466 --> 02:46:38,435 MONEY THEY WILL BE MAKING, BUT 4159 02:46:38,435 --> 02:46:40,837 HAS TO BE IN CHARGE OF PAY AND 4160 02:46:40,837 --> 02:46:43,907 LIKE A GAP IN THAT SETTING, 4161 02:46:43,907 --> 02:46:44,474 RIGHT? 4162 02:46:44,474 --> 02:46:46,543 BECAUSE WE CAN PAY WITH T32 NOT 4163 02:46:46,543 --> 02:46:49,279 AT THAT LEVEL, THE SALARY THEY 4164 02:46:49,279 --> 02:46:53,983 WILL BE MAKING AS CLINICIANS 4165 02:46:53,983 --> 02:46:54,217 100%. 4166 02:46:54,217 --> 02:46:58,355 WE ALSO GIVE MONEY FROM 4167 02:46:58,355 --> 02:46:59,456 SOCIETIES, WHATEVER IT IS, WE 4168 02:46:59,456 --> 02:47:02,192 USE THAT TO PAY THAT MONEY, THAT 4169 02:47:02,192 --> 02:47:06,863 GAP TO MAKE SURE IT'S NOT -- 4170 02:47:06,863 --> 02:47:08,231 >> IT'S AN INTERESTING IDEA. 4171 02:47:08,231 --> 02:47:15,939 THANK YOU FOR BRINGING IT UP. 4172 02:47:15,939 --> 02:47:17,741 >> ANY OTHER COMMENTS? 4173 02:47:17,741 --> 02:47:21,778 >> I REALLY AM EXCITED ABOUT 4174 02:47:21,778 --> 02:47:22,379 BRINGING ESPECIALLY SPECIALTY 4175 02:47:22,379 --> 02:47:24,647 ORGANIZATIONS TO THE TABLE ON 4176 02:47:24,647 --> 02:47:24,948 THIS. 4177 02:47:24,948 --> 02:47:28,151 THERE IS RIGHT NOW A RIFT IN THE 4178 02:47:28,151 --> 02:47:31,020 WAY WE TRAIN BOTH DDSs, THAT 4179 02:47:31,020 --> 02:47:32,689 SEEK A Ph.D., WHICH I THINK IS 4180 02:47:32,689 --> 02:47:35,859 A BETTER WAY TO BECOME A 4181 02:47:35,859 --> 02:47:37,394 CLINICIAN-SCIENTIST, ABSOLUTELY 4182 02:47:37,394 --> 02:47:38,828 FINISH THEIR DDS, BUT COMBINING 4183 02:47:38,828 --> 02:47:40,029 WITH A SPECIALTY. 4184 02:47:40,029 --> 02:47:40,964 THEN THE SPECIALTY SAYS ON ONE 4185 02:47:40,964 --> 02:47:47,003 HAND YOU HAVE TO BE COMMITTED 4186 02:47:47,003 --> 02:47:47,937 100%. 4187 02:47:47,937 --> 02:47:51,508 Ph.D. SIDE, NIH SIDE, YOU CAN 4188 02:47:51,508 --> 02:47:56,546 DO RESEARCH LESS THAN 80%, AGAIN 4189 02:47:56,546 --> 02:47:57,647 SPECIALTY DOESN'T LIKE TRAINING 4190 02:47:57,647 --> 02:48:02,218 TO BE SPLIT UP, AND I THINK IT'S 4191 02:48:02,218 --> 02:48:04,554 POSSIBLE SPLIT UP THAT LEVEL 4192 02:48:04,554 --> 02:48:05,321 CLINICAL TRAINING BUT THAT 4193 02:48:05,321 --> 02:48:06,956 DOESN'T SEEM TO SIT WELL AND 4194 02:48:06,956 --> 02:48:09,459 WE'VE HAD MANY PEOPLE WHO ARE 4195 02:48:09,459 --> 02:48:11,995 MENTORS OF THESE TRAINEES WRITE 4196 02:48:11,995 --> 02:48:13,730 TO US, CONCERNED ABOUT THIS. 4197 02:48:13,730 --> 02:48:23,139 AND UNLESS WE GET THEM TO THE 4198 02:48:23,139 --> 02:48:24,574 TABLE, ORTHODONTIC FOUNDATION, 4199 02:48:24,574 --> 02:48:26,342 PERIO, AND ALL THESE OTHERS, 4200 02:48:26,342 --> 02:48:28,311 THAT'S A GREAT DIRECTION, NOT 4201 02:48:28,311 --> 02:48:30,914 CREATING A NEW OFFICE THAT WILL 4202 02:48:30,914 --> 02:48:31,448 COST MONEY, DANA. 4203 02:48:31,448 --> 02:48:34,217 >> I THINK THE KEY POINT THOUGH 4204 02:48:34,217 --> 02:48:38,154 IS THEY NEED A GO-TO PERSON. 4205 02:48:38,154 --> 02:48:40,690 NOW, WHEN I SAY THE WORD 4206 02:48:40,690 --> 02:48:43,193 "OFFICE," IT CAN BE A ONE-PERSON 4207 02:48:43,193 --> 02:48:44,961 OFFICE. 4208 02:48:44,961 --> 02:48:49,098 I'M NOT THINKING A HUGE 4209 02:48:49,098 --> 02:48:52,268 CARIBBEAN PARTY BOAT THAT YOU 4210 02:48:52,268 --> 02:48:57,207 MAY BE THINKING OF, BUT I'M 4211 02:48:57,207 --> 02:48:59,509 THINKING OF A LONE INDIVIDUAL. 4212 02:48:59,509 --> 02:49:01,144 BUT THEY NEED THAT POINT PERSON, 4213 02:49:01,144 --> 02:49:04,113 THEY NEED TO BE ABLE TO GET ON 4214 02:49:04,113 --> 02:49:05,748 THE PHONE. 4215 02:49:05,748 --> 02:49:07,951 THE OTHER THING I THINK THAT'S 4216 02:49:07,951 --> 02:49:10,453 IMPORTANT, ALSO EXPANDING UPON 4217 02:49:10,453 --> 02:49:13,623 WHAT YOU JUST SAID, PROFESSIONAL 4218 02:49:13,623 --> 02:49:16,226 SOCIETIES WOULD LIKE NIDCR TO 4219 02:49:16,226 --> 02:49:19,829 COME TO THEM AND DISCUSS WITH 4220 02:49:19,829 --> 02:49:22,165 MEMBERS WHAT CHANGES DOES THEIR 4221 02:49:22,165 --> 02:49:23,333 PROFESSION NEED TO MAKE. 4222 02:49:23,333 --> 02:49:26,402 THEY EXPRESS A WILLINGNESS TO 4223 02:49:26,402 --> 02:49:27,270 CHANGE, BUT THEY NEED TO KNOW 4224 02:49:27,270 --> 02:49:28,171 HOW TO CHANGE. 4225 02:49:28,171 --> 02:49:33,142 THEY DON'T KNOW HOW TO. 4226 02:49:33,142 --> 02:49:33,977 >> EXACTLY. 4227 02:49:33,977 --> 02:49:37,046 I CAN'T TELL YOU HOW IMPORTANT 4228 02:49:37,046 --> 02:49:39,549 THAT IS, DANA, BECAUSE UNTIL 4229 02:49:39,549 --> 02:49:41,851 YOU -- AS A HANDS-ON CLINICIAN, 4230 02:49:41,851 --> 02:49:45,121 BEAR ON THE FRONT LINES, HAVE 4231 02:49:45,121 --> 02:49:46,022 CHAMPIONS, CLINICAL SERVICE, YOU 4232 02:49:46,022 --> 02:49:49,392 DO KNOW BETTER THAN ME, HOW 4233 02:49:49,392 --> 02:49:52,228 SILOED THESE DIVISIONS ARE IN 4234 02:49:52,228 --> 02:49:52,996 DENTAL SCHOOLS. 4235 02:49:52,996 --> 02:49:55,832 AND I DON'T KNOW WHAT IT IS 4236 02:49:55,832 --> 02:49:57,267 ABOUT DENTISTRY THAT WANTS TO 4237 02:49:57,267 --> 02:49:58,701 KEEP RESEARCH AND SCHOLARSHIP 4238 02:49:58,701 --> 02:50:01,971 AWAY, AT ARMS LENGTH, WHEN EVERY 4239 02:50:01,971 --> 02:50:02,972 SPECIALTY'S PRESENCE IS 4240 02:50:02,972 --> 02:50:07,343 THREATENED IN ACADEMIA RIGHT 4241 02:50:07,343 --> 02:50:07,510 NOW. 4242 02:50:07,510 --> 02:50:10,280 >> THE OTHER THING I HEAR, THE 4243 02:50:10,280 --> 02:50:14,217 FIRST WORDS ARE STUDENT DEBT, 4244 02:50:14,217 --> 02:50:15,652 WHICH REALLY CREATES, YOU KNOW, 4245 02:50:15,652 --> 02:50:16,953 A MOUNTAIN TO CLIMB BECAUSE THEY 4246 02:50:16,953 --> 02:50:18,821 ARE COMING OUT WITH THREE OR 4247 02:50:18,821 --> 02:50:20,023 FOUR HUNDRED THOUSAND DOLLARS IN 4248 02:50:20,023 --> 02:50:21,991 DEBT, BUT THEY ARE LOOKING FOR A 4249 02:50:21,991 --> 02:50:25,828 JOB THAT THEY CAN PAY THAT MONEY 4250 02:50:25,828 --> 02:50:26,062 BACK. 4251 02:50:26,062 --> 02:50:31,301 THERE'S JUST NOT ENOUGH GRANTS 4252 02:50:31,301 --> 02:50:32,802 AND STUFF, $20,000 A YEAR IS NOT 4253 02:50:32,802 --> 02:50:35,238 GOING TO PAY THAT OFF QUICKLY. 4254 02:50:35,238 --> 02:50:37,840 AND SO THAT'S A BARRIER. 4255 02:50:37,840 --> 02:50:39,809 IF THERE ARE WAYS, INNOVATIVE 4256 02:50:39,809 --> 02:50:42,478 WAYS, CREATIVE WAYS TO HELP WITH 4257 02:50:42,478 --> 02:50:50,119 THAT DEBT, I THINK THAT WOULD 4258 02:50:50,119 --> 02:50:50,320 HELP. 4259 02:50:50,320 --> 02:50:51,854 >> IS THAT SOMETHING NIDCR COULD 4260 02:50:51,854 --> 02:50:52,188 TAKE ON? 4261 02:50:52,188 --> 02:50:53,923 WE DON'T HAVE THE SCOPE OR 4262 02:50:53,923 --> 02:50:54,591 CHARGE. 4263 02:50:54,591 --> 02:50:57,794 WE OFFER LOAN REPAYMENT UP TO 4264 02:50:57,794 --> 02:51:01,164 THE TUNE OF $70,000 A YEAR OR 4265 02:51:01,164 --> 02:51:01,331 75? 4266 02:51:01,331 --> 02:51:01,864 >> FIFTY. 4267 02:51:01,864 --> 02:51:03,466 >> FOR THREE YEARS, AND 4268 02:51:03,466 --> 02:51:03,900 RENEWABLE. 4269 02:51:03,900 --> 02:51:07,537 THAT CAN BE SIZEABLE FOR SIX 4270 02:51:07,537 --> 02:51:07,737 YEARS. 4271 02:51:07,737 --> 02:51:08,271 >> YEAH. 4272 02:51:08,271 --> 02:51:10,139 >> BUT WHERE IS THE 4273 02:51:10,139 --> 02:51:11,240 RESPONSIBILITY FACTOR COMING 4274 02:51:11,240 --> 02:51:12,675 FORTH FROM OUR CLINICAL 4275 02:51:12,675 --> 02:51:14,644 COLLEAGUES? 4276 02:51:14,644 --> 02:51:19,882 AND I'M A DENTIST, I CAN SAY MY 4277 02:51:19,882 --> 02:51:20,216 COLLEAGUES. 4278 02:51:20,216 --> 02:51:26,923 WE'RE LOOKING FOR THAT RIGHT 4279 02:51:26,923 --> 02:51:27,090 NOW. 4280 02:51:27,090 --> 02:51:27,890 >> LET'S MOVE ON. 4281 02:51:27,890 --> 02:51:30,827 JACQUES HAD A HAND UP, AMY, AND 4282 02:51:30,827 --> 02:51:33,830 WE'LL HAVE TO MOVE ON. 4283 02:51:33,830 --> 02:51:35,632 >> SO DANA, I'M SO GLAD THAT YOU 4284 02:51:35,632 --> 02:51:40,236 BROUGHT UP THE MIND THE FUTURE 4285 02:51:40,236 --> 02:51:43,840 PROGRAM, A WONDERFUL PARTNERSHIP 4286 02:51:43,840 --> 02:51:45,375 BETWEEN NIDCR AND AODCR. 4287 02:51:45,375 --> 02:51:48,111 IT HAS BEEN EXTREMELY 4288 02:51:48,111 --> 02:51:51,948 SUCCESSFUL, AND SO MY POINT HERE 4289 02:51:51,948 --> 02:51:56,219 IS TO RECOGNIZE THIS EFFORT AND 4290 02:51:56,219 --> 02:51:59,055 SAY HOW PROUD WE ARE TO BE PART 4291 02:51:59,055 --> 02:52:03,660 OF IT, BUT ALSO TO THINK ABOUT 4292 02:52:03,660 --> 02:52:06,195 IS THERE ANY POSSIBILITY OF 4293 02:52:06,195 --> 02:52:10,566 EXPANDING THIS TYPE OF 4294 02:52:10,566 --> 02:52:17,240 PARTNERSHIP TO OTHER SPECIALTY 4295 02:52:17,240 --> 02:52:19,942 PROFESSIONAL SOCIETIES, AND 4296 02:52:19,942 --> 02:52:23,446 PERHAPS STIMULATE A SPECIALTY 4297 02:52:23,446 --> 02:52:27,083 PROFESSIONAL SOCIETY TO WORK 4298 02:52:27,083 --> 02:52:30,586 TOGETHER WITH NIDCR ON 4299 02:52:30,586 --> 02:52:34,290 DEVELOPING THE NEW GENERATION OF 4300 02:52:34,290 --> 02:52:34,757 DENTIST-SCIENTIST OR 4301 02:52:34,757 --> 02:52:36,826 ACADEMICIANS IN THAT AREA. 4302 02:52:36,826 --> 02:52:39,962 SO IT'S PERHAPS A SUGGESTION TO 4303 02:52:39,962 --> 02:52:41,197 THINK ABOUT. 4304 02:52:41,197 --> 02:52:42,331 >> SEVERAL OF THE SOCIETIES SAID 4305 02:52:42,331 --> 02:52:44,500 THEY WOULD LIKE TO DEVELOP A 4306 02:52:44,500 --> 02:52:50,406 PROGRAM TAILORED TO THEIR 4307 02:52:50,406 --> 02:52:51,808 SPECIALTY. 4308 02:52:51,808 --> 02:52:53,810 I THINK THAT'S A NATURAL FIT, 4309 02:52:53,810 --> 02:52:58,548 THAT'S A GOOD IDEA. 4310 02:52:58,548 --> 02:52:58,781 >> AMY? 4311 02:52:58,781 --> 02:53:01,718 >> I WAS -- YOU DID AN AMAZING 4312 02:53:01,718 --> 02:53:03,653 JOB LAYING OUT HOW UNBELIEVABLY 4313 02:53:03,653 --> 02:53:04,987 COMPLICATED IT IS TO GET 4314 02:53:04,987 --> 02:53:05,988 EVERYTHING RIGHT. 4315 02:53:05,988 --> 02:53:11,127 I WAS JUST GOING TO SHARE THAT 4316 02:53:11,127 --> 02:53:13,429 MY DEGREE IS IN CLINICAL 4317 02:53:13,429 --> 02:53:15,198 PSYCHOLOGY, AND THE WAY THOSE 4318 02:53:15,198 --> 02:53:18,568 TRAINING PROGRAMS ARE STRUCTURED 4319 02:53:18,568 --> 02:53:20,002 IS A CO-MINGLING OF THE CLINICAL 4320 02:53:20,002 --> 02:53:22,972 WORK YOU WANT TO SPECIALIZE IN 4321 02:53:22,972 --> 02:53:26,476 WITH THE RESEARCH TRAINING, SO 4322 02:53:26,476 --> 02:53:28,644 IF THE -- IF WE GET TO THE POINT 4323 02:53:28,644 --> 02:53:31,180 SPECIALTY TRAINING AND Ph.D. 4324 02:53:31,180 --> 02:53:33,816 PROGRAMS CAN BE COMBINED, IT 4325 02:53:33,816 --> 02:53:37,320 MIGHT BE WORTH SOME 4326 02:53:37,320 --> 02:53:37,887 CONVERSATIONS WITH CLINICAL 4327 02:53:37,887 --> 02:53:39,489 PSYCHOLOGY SOCIETIES, JUST TO 4328 02:53:39,489 --> 02:53:40,590 UNDERSTAND HOW THE STRUCTURES 4329 02:53:40,590 --> 02:53:46,996 WORK AND INCENTIVES WORK TO MAKE 4330 02:53:46,996 --> 02:53:47,463 THOSE THINGS VIABLE. 4331 02:53:47,463 --> 02:53:49,165 >> I THINK THAT'S A VERY GOOD 4332 02:53:49,165 --> 02:53:49,499 POINT. 4333 02:53:49,499 --> 02:53:54,437 TO EXPAND UPON WHAT YOU'RE 4334 02:53:54,437 --> 02:53:55,805 SAYING, THERE'S A DOCTORATE OF 4335 02:53:55,805 --> 02:53:57,473 SCIENCE PROGRAM AT UNIVERSITY OF 4336 02:53:57,473 --> 02:53:59,108 PENNSYLVANIA, AND I'M THE 4337 02:53:59,108 --> 02:54:01,878 DIRECTOR OF THAT PROGRAM, AND WE 4338 02:54:01,878 --> 02:54:03,846 TAILOR NOT ONLY -- NOT ONLY DO 4339 02:54:03,846 --> 02:54:06,249 WE TAILOR TO COMBINE THIS, THE 4340 02:54:06,249 --> 02:54:08,017 SPECIALTY, BUT EVERY SPECIALTY 4341 02:54:08,017 --> 02:54:09,786 HAS A DIFFERENT SCHEDULE. 4342 02:54:09,786 --> 02:54:12,488 SO, SOME SPECIALTIES DO ALL THE 4343 02:54:12,488 --> 02:54:13,689 CLINICAL TRAINING FIRST AND 4344 02:54:13,689 --> 02:54:15,458 DOCTOR OF SCIENCE RESEARCH 4345 02:54:15,458 --> 02:54:17,193 AFTERWARDS, SOME COMMINGLE IT. 4346 02:54:17,193 --> 02:54:22,098 SO IT STARTS OUT 20% CLINICAL, 4347 02:54:22,098 --> 02:54:27,270 ENDS UP -- I MEAN 20% RESEARCH, 4348 02:54:27,270 --> 02:54:29,238 ENDS UP 80%, EVERY YEAR IT 4349 02:54:29,238 --> 02:54:29,572 CHANGES. 4350 02:54:29,572 --> 02:54:30,506 HAVING PROGRAM FLEXIBILITY TO 4351 02:54:30,506 --> 02:54:33,709 MEET THE NEEDS OF A PARTICULAR 4352 02:54:33,709 --> 02:54:36,012 SPECIALTY IS ANOTHER FACTOR, AND 4353 02:54:36,012 --> 02:54:37,980 GOING TO OTHER DISCIPLINES AND 4354 02:54:37,980 --> 02:54:39,382 FINDING OUT HOW THEY DO IT I 4355 02:54:39,382 --> 02:54:40,750 THINK IS ALSO AN IMPORTANT 4356 02:54:40,750 --> 02:54:46,656 COMPONENT OF IT. 4357 02:54:46,656 --> 02:54:48,457 >> THANK YOU. 4358 02:54:48,457 --> 02:54:51,460 IF YOU HAVE ADDITIONAL COMMENTS 4359 02:54:51,460 --> 02:54:56,866 E-MAIL US LATER ON AT THE E-MAIL 4360 02:54:56,866 --> 02:54:57,900 ADDRESS OR MYSELF DIRECTLY. 4361 02:54:57,900 --> 02:55:01,204 AND I'D LIKE TO MOVE ON NOW TO 4362 02:55:01,204 --> 02:55:04,140 THE DATA SCIENCE STRATEGY 4363 02:55:04,140 --> 02:55:07,743 WORKING GROUP REPORT PROVIDED BY 4364 02:55:07,743 --> 02:55:17,920 DR. VISEL. 4365 02:55:19,856 --> 02:55:23,226 >> I HOPE YOU CAN SEE MY SCREEN 4366 02:55:23,226 --> 02:55:23,392 NOW. 4367 02:55:23,392 --> 02:55:25,261 >> YES, WE CAN. 4368 02:55:25,261 --> 02:55:26,028 >> OKAY. 4369 02:55:26,028 --> 02:55:29,432 SO, LET'S GET STARTED. 4370 02:55:29,432 --> 02:55:31,500 FIRST OF ALL, GOOD MORNING OR 4371 02:55:31,500 --> 02:55:33,269 GOOD AFTERNOON, EVERYBODY. 4372 02:55:33,269 --> 02:55:37,106 IT'S MY PLEASURE TO PRESENT HERE 4373 02:55:37,106 --> 02:55:40,042 THE FINAL REPORT FROM THE NIDCR 4374 02:55:40,042 --> 02:55:43,779 DATA SCIENCE STRATEGY WORKING 4375 02:55:43,779 --> 02:55:45,348 GROUP. 4376 02:55:45,348 --> 02:55:46,282 AND I WAS QUITE PLEASED 4377 02:55:46,282 --> 02:55:48,150 THROUGHOUT THE DAY SO FAR TO SEE 4378 02:55:48,150 --> 02:55:51,187 MANY OF THE TOPICS THAT WERE 4379 02:55:51,187 --> 02:55:52,822 MENTIONED THROUGHOUT THE DAY SO 4380 02:55:52,822 --> 02:55:57,226 FAR, SUCH AS THE BROADER NIDCR 4381 02:55:57,226 --> 02:56:02,365 STRATEGY, NEED TO ADDRESS HEALTH 4382 02:56:02,365 --> 02:56:04,367 DISPARITIES, OPPORTUNITIES FROM 4383 02:56:04,367 --> 02:56:11,040 INTEGRATING DENTAL AND/ AND 4384 02:56:11,040 --> 02:56:12,475 ORTHO, ALL REFLECTED IN THE WORK 4385 02:56:12,475 --> 02:56:14,110 OF OUR WORKING GROUP AND I WILL 4386 02:56:14,110 --> 02:56:24,320 COME BACK TO MANY OF THESE 4387 02:56:24,320 --> 02:56:24,620 THROUGHOUT. 4388 02:56:24,620 --> 02:56:27,256 SO, SO ALONG WITH THIS 4389 02:56:27,256 --> 02:56:28,557 PRESENTATION THERE'S THIS 4390 02:56:28,557 --> 02:56:30,459 WRITTEN REPORT. 4391 02:56:30,459 --> 02:56:32,728 SO WORKING GROUP HAS BEEN QUITE 4392 02:56:32,728 --> 02:56:33,062 BUSY. 4393 02:56:33,062 --> 02:56:34,797 OVER THE LAST TWO MONTHS WE'VE 4394 02:56:34,797 --> 02:56:37,099 PREPARED THIS WRITTEN REPORT, 4395 02:56:37,099 --> 02:56:39,168 IT'S PRETTY DETAILED, ALMOST 50 4396 02:56:39,168 --> 02:56:40,269 PAGES LONG. 4397 02:56:40,269 --> 02:56:43,239 AND FINAL DRAFT HAS BEEN 4398 02:56:43,239 --> 02:56:47,276 PROVIDED TO COUNCIL AND TO NIDCR 4399 02:56:47,276 --> 02:56:48,711 LEADERSHIP FOR COMMENTS, AND 4400 02:56:48,711 --> 02:56:50,346 THEN ONCE THOSE ARE RECEIVED 4401 02:56:50,346 --> 02:56:52,214 THIS WILL BE PUBLICLY POSTED. 4402 02:56:52,214 --> 02:56:55,484 WHAT I'LL DO OVER THE NEXT 40 4403 02:56:55,484 --> 02:56:57,687 MINUTES OR SO IS PROVIDE AN 4404 02:56:57,687 --> 02:56:59,855 OVERVIEW OF THE CONTENT OF THIS 4405 02:56:59,855 --> 02:57:02,258 REPORT, IN THE REPORT ITSELF WE 4406 02:57:02,258 --> 02:57:05,661 HAVE STRUCTURED LIKE THIS, WE 4407 02:57:05,661 --> 02:57:07,630 HAVE EXECUTIVE SUMMARY, WE 4408 02:57:07,630 --> 02:57:08,597 PROVIDED BACKGROUND, WHY THIS 4409 02:57:08,597 --> 02:57:11,033 REPORT AND WHY DATA SCIENCE 4410 02:57:11,033 --> 02:57:13,102 STRATEGY IS NEEDED. 4411 02:57:13,102 --> 02:57:14,203 WE PROVIDE GENERAL CONSIDERATION 4412 02:57:14,203 --> 02:57:16,505 ABOUT THE CURRENT LANDSCAPE OF 4413 02:57:16,505 --> 02:57:18,574 DATA SHARING IN GENERAL, AND 4414 02:57:18,574 --> 02:57:21,610 THEN MORE SPECIFICALLY WE FOCUS 4415 02:57:21,610 --> 02:57:25,514 ON THE DOC DATA LANDSCAPE, DOC 4416 02:57:25,514 --> 02:57:26,549 DATA ECO-SYSTEMS, SO THIS IS 4417 02:57:26,549 --> 02:57:29,618 MORE ANALYSIS OF WHAT WE HAVE IN 4418 02:57:29,618 --> 02:57:29,819 HAND. 4419 02:57:29,819 --> 02:57:33,856 AND THEN IN PERHAPS TWO MOST 4420 02:57:33,856 --> 02:57:37,059 IMPORTANT PARTS OF THE REPORT 4421 02:57:37,059 --> 02:57:39,028 POINT OUT DATA SCIENCE-RELATED 4422 02:57:39,028 --> 02:57:40,062 OPPORTUNITIES THAT ARE SPECIFIC 4423 02:57:40,062 --> 02:57:42,832 TO NIDCR WHERE WE SEE THE 4424 02:57:42,832 --> 02:57:45,835 BIGGEST POTENTIAL FOR DATA 4425 02:57:45,835 --> 02:57:47,570 SCIENCE AND FINALLY WE MAKE A 4426 02:57:47,570 --> 02:57:49,005 SET OF SPECIFIC RECOMMENDATIONS 4427 02:57:49,005 --> 02:57:52,808 BY THE WORKING GROUP THAT NIDCR 4428 02:57:52,808 --> 02:57:55,011 CAN TAKE INTO ACCOUNT, FOR 4429 02:57:55,011 --> 02:57:58,180 DEVELOPING MORE EXPLICIT DATA 4430 02:57:58,180 --> 02:57:59,615 SCIENCE STRATEGY. 4431 02:57:59,615 --> 02:58:03,753 SO, IN A NUTSHELL, WHAT THIS 4432 02:58:03,753 --> 02:58:09,125 REPORT IS ABOUT IS SO IT STARTED 4433 02:58:09,125 --> 02:58:10,326 WITH THE BROADER NIH-WIDE DATA 4434 02:58:10,326 --> 02:58:11,627 SCIENCE STRATEGY. 4435 02:58:11,627 --> 02:58:14,363 SO NIH HAS NOW FOR A LONG TIME 4436 02:58:14,363 --> 02:58:16,999 RECOGNIZED THE IMPORTANCE OF 4437 02:58:16,999 --> 02:58:22,138 DATA SCIENCE AND POTENTIAL FOR 4438 02:58:22,138 --> 02:58:23,239 DATA SCIENCE TRANSFORMED 4439 02:58:23,239 --> 02:58:24,440 BIOMEDICAL SCIENCES. 4440 02:58:24,440 --> 02:58:25,741 RELATED TO THIS NIDCR RECOGNIZES 4441 02:58:25,741 --> 02:58:28,711 THE IMPORTANCE OF DATA SCIENCE 4442 02:58:28,711 --> 02:58:32,948 FOR DOC RESEARCH, AT THE SAME 4443 02:58:32,948 --> 02:58:34,517 TIME THERE'S A GENERAL NIDCR 4444 02:58:34,517 --> 02:58:36,252 STRATEGIC PLAN BUT NO EXPLICIT 4445 02:58:36,252 --> 02:58:40,056 DATA SCIENCE STRATEGY FOR NIDCR. 4446 02:58:40,056 --> 02:58:42,691 THE WORKING GROUP THAT I'M 4447 02:58:42,691 --> 02:58:45,961 PRESENTING FOR TODAY WAS 4448 02:58:45,961 --> 02:58:49,598 ASSEMBLED IN SEPTEMBER 2022, SO 4449 02:58:49,598 --> 02:58:53,302 FOR THE NEXT 15 MONTHS WORKED ON 4450 02:58:53,302 --> 02:58:55,638 DEVELOPING RECOMMENDATIONS. 4451 02:58:55,638 --> 02:58:57,073 AND THIS CONSISTED OF 4452 02:58:57,073 --> 02:58:59,608 INFORMATION GATHERING PHASE 4453 02:58:59,608 --> 02:59:01,243 WHERE WE INVESTIGATED THE 4454 02:59:01,243 --> 02:59:03,446 CURRENT DATA ECOSYSTEM. 4455 02:59:03,446 --> 02:59:05,514 WE DID EFFORTS TO COLLECT 4456 02:59:05,514 --> 02:59:07,583 ADDITIONAL INPUTS FROM THE 4457 02:59:07,583 --> 02:59:08,350 LARGER COMMUNITY, LISTENING 4458 02:59:08,350 --> 02:59:12,621 SESSIONS AND REQUEST FOR 4459 02:59:12,621 --> 02:59:14,190 INFORMATION, COMPILED LISTS, 4460 02:59:14,190 --> 02:59:19,095 DATA TYPES, STANDARDS. 4461 02:59:19,095 --> 02:59:20,830 AND THEN WE SYNTHESIZED GENERAL 4462 02:59:20,830 --> 02:59:22,465 FINDINGS, PERHAPS THE MOST 4463 02:59:22,465 --> 02:59:26,368 NOTABLE ONES THAT WE OBSERVED, 4464 02:59:26,368 --> 02:59:28,637 COMPLEXITY AND HETEROGENEITY OF 4465 02:59:28,637 --> 02:59:31,774 THE DOC DATA AS IT CURRENTLY 4466 02:59:31,774 --> 02:59:33,876 EXISTS WHICH RESULTS IN VARIOUS 4467 02:59:33,876 --> 02:59:35,845 CHALLENGES, FOR EXAMPLE WITH THE 4468 02:59:35,845 --> 02:59:41,750 IDEA OF FAIR COMPLIANCE, MAKING 4469 02:59:41,750 --> 02:59:42,885 DATA FINDABLE, ACCESSIBLE, 4470 02:59:42,885 --> 02:59:44,053 INTRAOPERABLE, REUSABLE. 4471 02:59:44,053 --> 02:59:45,888 THEN IN TERMS OF OPPORTUNITIES 4472 02:59:45,888 --> 02:59:48,958 THERE WERE FOUR MAJOR AREAS 4473 02:59:48,958 --> 02:59:51,360 WHERE WE IDENTIFIED AND OUTLINED 4474 02:59:51,360 --> 02:59:56,599 SPECIFIC OPPORTUNITIES THAT WE 4475 02:59:56,599 --> 02:59:58,234 BELIEVE ARE IMPORTANT TO NIDCR 4476 02:59:58,234 --> 03:00:01,537 AND DOC RESEARCH SPACE, THESE 4477 03:00:01,537 --> 03:00:03,939 RELATE TO OPPORTUNITIES IN 4478 03:00:03,939 --> 03:00:06,108 HEALTH DISPARITIES AND 4479 03:00:06,108 --> 03:00:07,309 ADDRESSING THEM, RELATED TO 4480 03:00:07,309 --> 03:00:08,310 ARTIFICIAL INTELLIGENCE AND 4481 03:00:08,310 --> 03:00:10,513 MACHINE LEARNING, AND MAKING 4482 03:00:10,513 --> 03:00:13,482 SURE THAT DOC DATA IS READY FOR 4483 03:00:13,482 --> 03:00:19,488 APPLICATIONS OF A.I. AND M.L., 4484 03:00:19,488 --> 03:00:22,124 CONVERTING DATA TO APPLICATIONS, 4485 03:00:22,124 --> 03:00:24,393 AND HOW WE CAN LEVERAGE THIS 4486 03:00:24,393 --> 03:00:27,363 DIVERSITY OF DATA SO THAT 4487 03:00:27,363 --> 03:00:29,665 THERE'S THIS COMPLEXITY OF 4488 03:00:29,665 --> 03:00:30,399 HETEROGENEITY WITH CHALLENGES 4489 03:00:30,399 --> 03:00:31,734 BUT WE BELIEVE THERE ARE 4490 03:00:31,734 --> 03:00:34,904 OPPORTUNITIES SPECIFICALLY 4491 03:00:34,904 --> 03:00:36,772 RELATED TO THIS. 4492 03:00:36,772 --> 03:00:38,507 FINALLY IN OUR RECOMMENDATIONS, 4493 03:00:38,507 --> 03:00:40,509 WE HAVE FIVE BIG AREAS WHERE WE 4494 03:00:40,509 --> 03:00:41,844 MAKE RECOMMENDATIONS. 4495 03:00:41,844 --> 03:00:46,081 THE FIRST ONE IS TO CREATE 4496 03:00:46,081 --> 03:00:49,118 INFRASTRUCTURE, TAILORED FOR DOC 4497 03:00:49,118 --> 03:00:50,419 RESEARCH. 4498 03:00:50,419 --> 03:00:51,654 THEN IN THIS INFRASTRUCTURE, 4499 03:00:51,654 --> 03:00:54,757 MODERNIZE EXISTING AND CREATE 4500 03:00:54,757 --> 03:00:56,158 NEW DOC-SPECIFIC DATA 4501 03:00:56,158 --> 03:00:56,892 ECOSYSTEMS. 4502 03:00:56,892 --> 03:00:59,395 THIRD ONE RELATES TO DEVELOPMENT 4503 03:00:59,395 --> 03:01:02,932 OF TOOLS FOR THINGS SUCH AS 4504 03:01:02,932 --> 03:01:06,435 MANAGEMENT OF DATA, ANALYSIS OF 4505 03:01:06,435 --> 03:01:08,404 DATA AND VISUALIZATION. 4506 03:01:08,404 --> 03:01:11,240 FOURTH REALLY IMPORTANT ONE IS 4507 03:01:11,240 --> 03:01:14,210 RELATED TO WORKFORCE DEVELOPMENT 4508 03:01:14,210 --> 03:01:15,411 AND INCLUSIVE TRAINING 4509 03:01:15,411 --> 03:01:19,014 SPECIFICALLY AIMED AT ENHANCING 4510 03:01:19,014 --> 03:01:20,749 DATA SCIENCE WITHIN DOC 4511 03:01:20,749 --> 03:01:22,184 RESEARCH. 4512 03:01:22,184 --> 03:01:24,920 LAST IS THE ROLE NIDCR COULD AND 4513 03:01:24,920 --> 03:01:27,089 PROBABLY SHOULD PLAY IN TERMS OF 4514 03:01:27,089 --> 03:01:28,524 STEWARDSHIP FOR DATA AND 4515 03:01:28,524 --> 03:01:29,825 SUSTAINABLE DATA POLICIES. 4516 03:01:29,825 --> 03:01:32,328 SO, I'LL TALK ABOUT ALL OF THIS 4517 03:01:32,328 --> 03:01:33,829 IN MORE DETAIL IN THE REST OF 4518 03:01:33,829 --> 03:01:34,430 THE PRESENTATION. 4519 03:01:34,430 --> 03:01:39,335 THIS IS JUST TO GIVE A HEADS UP. 4520 03:01:39,335 --> 03:01:42,304 SO, WE HAVE SEEN THIS REPORT A 4521 03:01:42,304 --> 03:01:48,344 FEW TIMES TODAY SO FAR, AND 4522 03:01:48,344 --> 03:01:49,745 WE'VE SEEN STRATEGIC PRIORITIES. 4523 03:01:49,745 --> 03:01:52,248 THIS CAME OUT TWO YEARS AGO, 4524 03:01:52,248 --> 03:01:57,620 ALMOST THREE YEARS AGO AT THIS 4525 03:01:57,620 --> 03:02:01,457 POINT, AND FIVE STRATEGIC 4526 03:02:01,457 --> 03:02:02,825 PRIORITIES DRIVE NIDCR IN THE 4527 03:02:02,825 --> 03:02:03,559 YEARS AHEAD. 4528 03:02:03,559 --> 03:02:07,997 THIS WAS ONE OF THE MOTIVATIONS, 4529 03:02:07,997 --> 03:02:09,832 THAT DATA SCIENCE IS CRITICAL 4530 03:02:09,832 --> 03:02:13,402 FOR ACHIEVING SUCCESS IN ALL OF 4531 03:02:13,402 --> 03:02:14,803 THESE FIVE NIDCR STRATEGIC 4532 03:02:14,803 --> 03:02:15,337 PRIORITIES. 4533 03:02:15,337 --> 03:02:16,772 WHAT I DID IS PULL OUT SOME 4534 03:02:16,772 --> 03:02:21,610 BULLETS YOU CAN FIND IN THIS 4535 03:02:21,610 --> 03:02:23,879 REPORT, THAT RELY HEAVILY ON 4536 03:02:23,879 --> 03:02:26,749 IMPROVED DATA SCIENCE APPROACHES 4537 03:02:26,749 --> 03:02:29,385 AND SYSTEMS. 4538 03:02:29,385 --> 03:02:31,887 SO, DATA SCIENCE IMPLICITLY IS 4539 03:02:31,887 --> 03:02:32,888 REFERENCED THROUGH THIS REPORT, 4540 03:02:32,888 --> 03:02:35,624 AT THE SAME TIME IT IS NOT QUITE 4541 03:02:35,624 --> 03:02:38,160 CLEAR HOW WE WOULD GET THERE, 4542 03:02:38,160 --> 03:02:41,330 BECAUSE THERE IS NO EXPLICIT 4543 03:02:41,330 --> 03:02:42,931 DATA SCIENCE STRATEGY FOR NIDCR. 4544 03:02:42,931 --> 03:02:50,839 AND WITH THIS IN MIND, RENA IN 4545 03:02:50,839 --> 03:02:53,008 2022 IN ANTICIPATION PERHAPS OF 4546 03:02:53,008 --> 03:02:55,210 WHAT WE HEARD ABOUT TODAY IN THE 4547 03:02:55,210 --> 03:02:59,948 SLIDE FROM THE NIH DIRECTOR 4548 03:02:59,948 --> 03:03:00,783 CONVENED THIS WORKING GROUP. 4549 03:03:00,783 --> 03:03:04,386 SO THE IDEA WAS TO PUT TOGETHER 4550 03:03:04,386 --> 03:03:08,223 A DATA SCIENCE STRATEGY WORKING 4551 03:03:08,223 --> 03:03:12,828 GROUP THAT WOULD ADVISE COUNCIL 4552 03:03:12,828 --> 03:03:16,231 AND NIDCR FOR DEVELOPING A -- SO 4553 03:03:16,231 --> 03:03:17,700 PROVIDING RECOMMENDATIONS FOR 4554 03:03:17,700 --> 03:03:20,803 PROVIDING A WELL-INFORMED AND 4555 03:03:20,803 --> 03:03:23,439 WELL-REASONED NIDCR DATA SCIENCE 4556 03:03:23,439 --> 03:03:26,842 STRATEGY THAT MAKES SURE THAT 4557 03:03:26,842 --> 03:03:28,043 FORWARD-LOOKING MANNER NIDCR CAN 4558 03:03:28,043 --> 03:03:30,479 REALIZE FULL POTENTIAL OF DATA 4559 03:03:30,479 --> 03:03:33,716 SCIENCE ACROSS THE ENTIRE 4560 03:03:33,716 --> 03:03:36,418 SPECTRUM OF NIDCR'S MISSION. 4561 03:03:36,418 --> 03:03:38,253 IMPORTANTLY, OUR TASK WAS NOT TO 4562 03:03:38,253 --> 03:03:42,491 DEVELOP A STRATEGIC PLAN TO 4563 03:03:42,491 --> 03:03:43,826 PROVIDE RECOMMENDATIONS THAT CAN 4564 03:03:43,826 --> 03:03:47,830 DRIVE DEVELOPMENT OF SUCH A 4565 03:03:47,830 --> 03:03:48,530 STRATEGY. 4566 03:03:48,530 --> 03:03:50,065 THIS SLIDE YOU SEE THE MEMBERS 4567 03:03:50,065 --> 03:03:51,600 OF THE WORKING GROUP. 4568 03:03:51,600 --> 03:03:53,569 AND I REALLY WANT TO SAY THAT WE 4569 03:03:53,569 --> 03:03:56,872 HAD A BRILLIANT SET OF PEOPLE 4570 03:03:56,872 --> 03:03:58,741 FROM ACROSS THE SPECTRUM. 4571 03:03:58,741 --> 03:04:00,909 YOU CAN SEE HERE ON THE LEFT 4572 03:04:00,909 --> 03:04:01,777 THESE ARE -- THIS IS THE 4573 03:04:01,777 --> 03:04:06,715 OFFICIAL ROSTER OF THE WORKING 4574 03:04:06,715 --> 03:04:07,282 GROUP. 4575 03:04:07,282 --> 03:04:09,017 AND LOOKING YOU CAN SEE THEY 4576 03:04:09,017 --> 03:04:10,886 COVERED A WIDE SPECTRUM OF 4577 03:04:10,886 --> 03:04:12,955 EXPERTISE, LOOKING AT 4578 03:04:12,955 --> 03:04:15,591 ORGANIZATIONS WE HAVE 4579 03:04:15,591 --> 03:04:16,625 UNIVERSITIES AS WELL AS 4580 03:04:16,625 --> 03:04:19,528 ORGANIZATIONS AND COMPANIES IN 4581 03:04:19,528 --> 03:04:22,064 THE PRIVATE SECTOR TO REALLY 4582 03:04:22,064 --> 03:04:23,832 HAVE A BROAD REPRESENTATION. 4583 03:04:23,832 --> 03:04:26,535 WE ALSO HAD A NUMBER OF NIDCR 4584 03:04:26,535 --> 03:04:27,736 STAFF WHO WERE NOT TECHNICALLY 4585 03:04:27,736 --> 03:04:29,671 PART OF THE WORKING GROUP BUT 4586 03:04:29,671 --> 03:04:32,975 WHO PARTICIPATED IN MANY OF OUR 4587 03:04:32,975 --> 03:04:33,609 SESSIONS. 4588 03:04:33,609 --> 03:04:34,843 AND PROVIDED NIDCR PERSPECTIVE 4589 03:04:34,843 --> 03:04:37,579 AND SUPPORT FOR MANY OF THE 4590 03:04:37,579 --> 03:04:39,314 ASPECTS OF THE WORK, OF OUR 4591 03:04:39,314 --> 03:04:39,615 GROUP. 4592 03:04:39,615 --> 03:04:45,788 ALSO I WANT TO CALL OUT CHRIS 4593 03:04:45,788 --> 03:04:48,957 WILLIAMS, CRITICAL IN HELPING US 4594 03:04:48,957 --> 03:04:51,126 ORGANIZING OUR LISTENING 4595 03:04:51,126 --> 03:04:52,094 SESSIONS FOR COMMUNITY. 4596 03:04:52,094 --> 03:04:54,463 I WANT TO SAY THANKS TO ALL THE 4597 03:04:54,463 --> 03:04:57,499 PEOPLE SHOWN HERE ON THE SLIDE 4598 03:04:57,499 --> 03:04:59,802 REALLY CRITICAL IN DEVELOPING 4599 03:04:59,802 --> 03:05:02,838 CONTENT OF OUR REPORT AND FOR 4600 03:05:02,838 --> 03:05:04,173 EVERYTHING THAT I'M GOING TO 4601 03:05:04,173 --> 03:05:13,449 SHOW IN THE REMAINDER OF THE 4602 03:05:13,449 --> 03:05:13,782 PRESENTATION. 4603 03:05:13,782 --> 03:05:15,651 WHEN WE THOUGHT WHO SHOULD BE ON 4604 03:05:15,651 --> 03:05:17,319 THE WORKING GROUP ONE IMPORTANT 4605 03:05:17,319 --> 03:05:21,156 CONSIDERATION WAS WE WANTED TO 4606 03:05:21,156 --> 03:05:25,961 COVER THE ENTIRE CONSTELLATION 4607 03:05:25,961 --> 03:05:29,998 OF CONTINUUM, KEY LEVELS FROM T0 4608 03:05:29,998 --> 03:05:32,501 TO TRANSLATION TO HUMAN, TO 4609 03:05:32,501 --> 03:05:34,269 PRACTICE, INTO COMMUNITIES. 4610 03:05:34,269 --> 03:05:37,539 AND YOU SEE HERE ARE 12 WORKING 4611 03:05:37,539 --> 03:05:40,509 GROUP MEMBERS WITH THEIR 4612 03:05:40,509 --> 03:05:42,377 RESPECTIVE AREAS OF EXPERTISE 4613 03:05:42,377 --> 03:05:43,045 INDICATED. 4614 03:05:43,045 --> 03:05:44,913 YOU CAN SEE WITHIN THE WORKING 4615 03:05:44,913 --> 03:05:47,382 GROUP THERE WAS A SUBSTANTIAL 4616 03:05:47,382 --> 03:05:51,019 AMOUNT OF EXPERTISE ACROSS THE 4617 03:05:51,019 --> 03:05:51,286 SPECTRUM. 4618 03:05:51,286 --> 03:05:54,223 SO, WHEN WE STARTED OUT WITH 4619 03:05:54,223 --> 03:05:57,426 THIS WORKING GROUP, OUR FIRST 4620 03:05:57,426 --> 03:06:04,399 THOUGHT WAS AS A STARTING POINT 4621 03:06:04,399 --> 03:06:07,135 LET'S ASSESS STATUS QUO, TRY TO 4622 03:06:07,135 --> 03:06:08,036 UNDERSTAND CURRENT DATA 4623 03:06:08,036 --> 03:06:09,137 ECOSYSTEM AND GENERAL LANDSCAPE 4624 03:06:09,137 --> 03:06:11,740 OF DOC DATA SCIENCE LOOKS LIKE. 4625 03:06:11,740 --> 03:06:13,709 SO, WE THOUGHT LET'S HAVE A LOOK 4626 03:06:13,709 --> 03:06:16,578 AT ALL THE SYSTEMS AND DATA 4627 03:06:16,578 --> 03:06:18,747 TYPES THAT PEOPLE USE, WE 4628 03:06:18,747 --> 03:06:20,282 STARTED TO COMPILE LISTS AND 4629 03:06:20,282 --> 03:06:23,785 STARTED TO THINK HOW THINGS 4630 03:06:23,785 --> 03:06:25,587 RELATE, AND VERY QUICKLY WE 4631 03:06:25,587 --> 03:06:27,956 REALIZED THIS WAS MUCH MORE 4632 03:06:27,956 --> 03:06:33,529 COMPLEX THAN ANY OF US HAD 4633 03:06:33,529 --> 03:06:34,296 ANTICIPATED. 4634 03:06:34,296 --> 03:06:35,531 DOZENS OF DATA SYSTEMS, DATA 4635 03:06:35,531 --> 03:06:37,900 TYPES, DATA USE CASES. 4636 03:06:37,900 --> 03:06:40,536 I USE HERE GENERATIVE A.I., 4637 03:06:40,536 --> 03:06:46,041 THINKING TO THE GENERAL TOPIC, 4638 03:06:46,041 --> 03:06:47,109 TO VISUALIZE WHAT THE WORKING 4639 03:06:47,109 --> 03:06:48,844 GROUP FELT LIKE AS WE WENT 4640 03:06:48,844 --> 03:06:52,681 THROUGH THE SYSTEM, WE HAD 4641 03:06:52,681 --> 03:06:54,583 DOZENS OF THINGS, PROBABLY STILL 4642 03:06:54,583 --> 03:06:56,618 DIDN'T CAPTURE ALL OF IT. 4643 03:06:56,618 --> 03:06:59,655 WE DECIDED THAT WE WANTED TO GET 4644 03:06:59,655 --> 03:07:02,958 ADDITIONAL COMMUNITY INPUT. 4645 03:07:02,958 --> 03:07:05,160 SO, WE PERFORMED SOME 4646 03:07:05,160 --> 03:07:06,395 INFORMATION GATHERING EXERCISE 4647 03:07:06,395 --> 03:07:13,235 AND USED TWO PRIMARY MECHANISMS, 4648 03:07:13,235 --> 03:07:14,102 FIRST CONDUCTED LISTENING 4649 03:07:14,102 --> 03:07:16,438 SESSIONS TO REACH OUT TO 4650 03:07:16,438 --> 03:07:18,607 COMMUNITY MEMBERS IN THE DOC 4651 03:07:18,607 --> 03:07:26,181 RESEARCH SPACE, MANY OF THESE 4652 03:07:26,181 --> 03:07:27,749 ARE ACTUALLY PREVIOUS GRANTEES, 4653 03:07:27,749 --> 03:07:38,393 PROVIDE THESE PEOPLE 10 TO 20 4654 03:07:38,393 --> 03:07:39,761 PER SESSION, AND THEN PRESENT 4655 03:07:39,761 --> 03:07:41,930 QUESTIONS TO GET INPUT. 4656 03:07:41,930 --> 03:07:43,332 RELATED TO THESE LISTENING 4657 03:07:43,332 --> 03:07:53,809 SESSIONS I CALL OUT CRIS AND 4658 03:07:54,009 --> 03:07:56,478 ALICIA CHOU, GETTING ORGANIZED, 4659 03:07:56,478 --> 03:08:00,082 LOGISTICS, HELPING US DIGEST 4660 03:08:00,082 --> 03:08:01,717 INPUTS IN A MANNER LIKE 4661 03:08:01,717 --> 03:08:04,553 COMPILING A WAY THE WORKING 4662 03:08:04,553 --> 03:08:12,995 GROUP COULD USING FOR DEVELOPING 4663 03:08:12,995 --> 03:08:14,162 OBSERVATIONS RECOMMENDATIONS, 4664 03:08:14,162 --> 03:08:17,933 OTHER WAS REQUEST OF 4665 03:08:17,933 --> 03:08:18,233 INFORMATION. 4666 03:08:18,233 --> 03:08:20,802 THIS USED SOME SAME QUESTIONS IN 4667 03:08:20,802 --> 03:08:21,770 THE LISTENING SESSIONS BUT 4668 03:08:21,770 --> 03:08:24,740 BROUGHT THESE TO A BROADER 4669 03:08:24,740 --> 03:08:26,808 COMMUNITY SO ANYONE COULD SUBMIT 4670 03:08:26,808 --> 03:08:37,319 COMMENTS, RELEASED ALSO IN THE 4671 03:08:40,922 --> 03:08:41,089 SUMMER. 4672 03:08:41,089 --> 03:08:44,359 AND SUPPORT FOR THE PROCESS OF 4673 03:08:44,359 --> 03:08:47,863 RELEASING, IN ORGANIZING THE 4674 03:08:47,863 --> 03:08:48,864 LARGE AMOUNT OF INPUT. 4675 03:08:48,864 --> 03:08:51,299 TO GIVE A SENSE OF THE KIND OF 4676 03:08:51,299 --> 03:08:56,405 QUESTIONS THAT WORKING GROUP 4677 03:08:56,405 --> 03:09:00,042 WANTED INPUT ON, WE ASKED PEOPLE 4678 03:09:00,042 --> 03:09:02,444 WHO GENERATE DATA WHAT KINDS OF 4679 03:09:02,444 --> 03:09:05,380 DATA THEY GENERATE, HOW THEY 4680 03:09:05,380 --> 03:09:07,015 CURRENTLY STORE DATA. 4681 03:09:07,015 --> 03:09:09,518 WE ALSO HAVE PEOPLE PRIMARILY 4682 03:09:09,518 --> 03:09:11,620 DATA USERS AND REANALYZE DATA 4683 03:09:11,620 --> 03:09:12,721 PRODUCED BY OTHERS. 4684 03:09:12,721 --> 03:09:13,689 THESE PEOPLE WE ASKED WHAT KIND 4685 03:09:13,689 --> 03:09:19,261 OF DATA DO THEY USE, AND WHERE 4686 03:09:19,261 --> 03:09:21,430 DO THEY GET THIS DATA, WHAT ARE 4687 03:09:21,430 --> 03:09:21,797 THE SOURCES? 4688 03:09:21,797 --> 03:09:26,501 FOR PEOPLE WHO PRODUCE DATA AND 4689 03:09:26,501 --> 03:09:28,904 SHARE IT, WE ASKED HOW OFTEN 4690 03:09:28,904 --> 03:09:30,772 THEY SHARE, WHAT MECHANISMS THEY 4691 03:09:30,772 --> 03:09:31,073 USE. 4692 03:09:31,073 --> 03:09:33,108 FOR PEOPLE WHO GENERATE DATA BUT 4693 03:09:33,108 --> 03:09:34,276 DON'T CURRENTLY SHARE IT WE 4694 03:09:34,276 --> 03:09:36,578 WANTED TO KNOW WHAT BARRIERS TO 4695 03:09:36,578 --> 03:09:40,215 DATA SHARING THEY CURRENTLY 4696 03:09:40,215 --> 03:09:40,615 EXPERIENCE. 4697 03:09:40,615 --> 03:09:42,284 WE ASKED ABOUT DATA STANDARDS. 4698 03:09:42,284 --> 03:09:48,824 THIS IS OF COURSE REALLY 4699 03:09:48,824 --> 03:09:51,359 IMPORTANT FOR MAKING DATA FOR 4700 03:09:51,359 --> 03:09:52,027 INTEGRATIVE STUDIES, WE ASKED 4701 03:09:52,027 --> 03:09:55,297 WHAT KIND OF DATA STANDARDS THEY 4702 03:09:55,297 --> 03:09:56,965 USE, COMMON DATA ELEMENTS WE 4703 03:09:56,965 --> 03:09:58,366 HEARD ABOUT EARLIER TODAY, 4704 03:09:58,366 --> 03:09:59,801 ONTOLOGY, IF SO WHICH ARE 4705 03:09:59,801 --> 03:10:02,104 IMPORTANT, AND WANTED TO KNOW IF 4706 03:10:02,104 --> 03:10:03,839 THERE ARE ANY GAPS IN THE 4707 03:10:03,839 --> 03:10:06,141 CURRENT SYSTEM OF STANDARDS THAT 4708 03:10:06,141 --> 03:10:08,343 EXIST, DO PEOPLE PRODUCE DATA 4709 03:10:08,343 --> 03:10:11,513 WHERE THERE ARE NO CURRENT 4710 03:10:11,513 --> 03:10:13,482 APPLICABLE DATA STANDARDS TODAY. 4711 03:10:13,482 --> 03:10:16,017 FINALLY WE ASKED EVERYBODY 4712 03:10:16,017 --> 03:10:17,219 OPEN-ENDED QUESTIONS, SO 4713 03:10:17,219 --> 03:10:24,326 THINKING ABOUT THE FUTURE OF THE 4714 03:10:24,326 --> 03:10:26,061 DOC DATA ECOSYSTEM WHAT THEY 4715 03:10:26,061 --> 03:10:27,162 FEEL IS IMPORTANT, TOP 4716 03:10:27,162 --> 03:10:29,231 PRIORITIES RELEVANT TO THEIR 4717 03:10:29,231 --> 03:10:29,464 WORK. 4718 03:10:29,464 --> 03:10:31,099 WHAT I'M SHOWING ARE QUESTIONS 4719 03:10:31,099 --> 03:10:34,503 WE ASKED IN THE LISTENING 4720 03:10:34,503 --> 03:10:37,773 SESSIONS, IN THE RFI ASKED A 4721 03:10:37,773 --> 03:10:40,342 SIMILAR SET OF QUESTIONS, 4722 03:10:40,342 --> 03:10:45,347 OVERLAPPING AND A FEW MORE 4723 03:10:45,347 --> 03:10:45,981 COMPREHENSIVE VIEW WILL BE IN 4724 03:10:45,981 --> 03:10:47,549 THE WRITTEN REPORT. 4725 03:10:47,549 --> 03:10:50,585 WHAT KIND OF INPUT? 4726 03:10:50,585 --> 03:10:53,555 SO THIS CONFIRMED, AND 4727 03:10:53,555 --> 03:10:54,856 REINFORCED, OUR EARLY 4728 03:10:54,856 --> 03:10:55,423 OBSERVATIONS. 4729 03:10:55,423 --> 03:10:58,026 WHEN WE ASKED ABOUT DATA TYPES, 4730 03:10:58,026 --> 03:10:59,995 WE GET AN ENORMOUS NUMBER. 4731 03:10:59,995 --> 03:11:06,768 THIS IS JUST -- PEOPLE REPORTED 4732 03:11:06,768 --> 03:11:09,771 OVER 65 DATA TYPES. 4733 03:11:09,771 --> 03:11:12,040 WHEN YOU LOOK CLOSELY, SOME OF 4734 03:11:12,040 --> 03:11:13,809 THESE ARE NOT ACTUALLY A SINGLE 4735 03:11:13,809 --> 03:11:17,279 DATA TYPE, A GROUP OF DATA TYPES 4736 03:11:17,279 --> 03:11:20,582 THAT HAVE DIFFERENT ACTUAL DATA 4737 03:11:20,582 --> 03:11:23,618 TYPES UNDERNEATH IT. 4738 03:11:23,618 --> 03:11:27,122 THIS IS JUST AN ABBREVIATED 4739 03:11:27,122 --> 03:11:28,156 ABBREVIATED VERSION. 4740 03:11:28,156 --> 03:11:30,192 FOR THE FULL LIST LOOK IN THE 4741 03:11:30,192 --> 03:11:33,128 REPORT, ORGANIZED BY DIFFERENT 4742 03:11:33,128 --> 03:11:36,565 KINDS OF CATEGORIES, TO HELP 4743 03:11:36,565 --> 03:11:38,099 WITH DIGESTING THIS INFORMATION. 4744 03:11:38,099 --> 03:11:41,937 THE SAME IS TRUE WHEN WE ASKED 4745 03:11:41,937 --> 03:11:43,772 ABOUT DATA SYSTEMS PEOPLE USE. 4746 03:11:43,772 --> 03:11:48,443 DATA SYSTEMS MEANING ANY TYPE OF 4747 03:11:48,443 --> 03:11:52,447 DATABASES, REPOSITORY, TOOLS AND 4748 03:11:52,447 --> 03:11:54,649 SO ON. 4749 03:11:54,649 --> 03:11:58,220 AGAIN, INPUTS WE GET FROM 4750 03:11:58,220 --> 03:11:59,487 COMMUNITY VASTLY EXPANDED THE 4751 03:11:59,487 --> 03:12:01,423 INITIAL LONG LIST WE GENERATED 4752 03:12:01,423 --> 03:12:03,625 FROM THE WORKING GROUP MEMBERS 4753 03:12:03,625 --> 03:12:05,160 ONWARD INITIALLY. 4754 03:12:05,160 --> 03:12:06,695 THERE WAS A TOTAL OF OVER 60 4755 03:12:06,695 --> 03:12:09,664 DATA SYSTEMS THAT WERE 4756 03:12:09,664 --> 03:12:11,399 IDENTIFIED. 4757 03:12:11,399 --> 03:12:12,734 I'M SHOWING LETTERS A-F, FULL 4758 03:12:12,734 --> 03:12:14,269 LIST IS AGAIN IN THE REPORT. 4759 03:12:14,269 --> 03:12:19,107 WHAT I WANT TO POINT OUT HERE IS 4760 03:12:19,107 --> 03:12:21,910 TURNS OUT THAT TIMES OF DATA 4761 03:12:21,910 --> 03:12:23,979 SYSTEMS THAT DOC RESEARCHERS 4762 03:12:23,979 --> 03:12:30,151 CURRENTLY USE ARE A MIX OF 4763 03:12:30,151 --> 03:12:32,420 SYSTEMS THAT ARE VERY EXPLICITLY 4764 03:12:32,420 --> 03:12:37,058 CREATED BY AND FOR DOC RESEARCH. 4765 03:12:37,058 --> 03:12:39,127 FOR EXAMPLE, DENTAL DATABASES OR 4766 03:12:39,127 --> 03:12:43,064 FACEBASE AS A MAJOR MOSTLY BASIC 4767 03:12:43,064 --> 03:12:44,599 RESEARCH FOCUSED REPOSITORY. 4768 03:12:44,599 --> 03:12:46,902 BUT THEN THERE ARE ALSO MANY 4769 03:12:46,902 --> 03:12:48,870 OTHER TYPES OF SYSTEMS THAT ARE 4770 03:12:48,870 --> 03:12:51,706 MORE GENERAL HEALTH RELATED OR 4771 03:12:51,706 --> 03:12:54,175 IN SOME CASES NOT HEALTH RELATED 4772 03:12:54,175 --> 03:12:55,310 AT ALL. 4773 03:12:55,310 --> 03:12:59,080 THESE WERE NOT BUILT FOR 4774 03:12:59,080 --> 03:13:01,316 CLASSIFICATION, FOR EXAMPLE, 4775 03:13:01,316 --> 03:13:02,083 GENERAL CENSUS DATA WHICH WOULD 4776 03:13:02,083 --> 03:13:06,554 BE IMPORTANT SOURCE OF INPUT FOR 4777 03:13:06,554 --> 03:13:08,657 TAKING A HOLISTIC APPROACH FOR 4778 03:13:08,657 --> 03:13:09,858 ANALYSIS OF HEALTH DISPARITIES, 4779 03:13:09,858 --> 03:13:14,462 SO BROAD SPECTRUM OF DATA 4780 03:13:14,462 --> 03:13:14,863 SYSTEMS. 4781 03:13:14,863 --> 03:13:17,232 WE GET A LOT OF SPECIFIC 4782 03:13:17,232 --> 03:13:19,034 COMMENTS AND SUGGESTIONS FROM 4783 03:13:19,034 --> 03:13:20,468 THE COMMUNITY. 4784 03:13:20,468 --> 03:13:23,772 I PUT OUT THIS HANDFUL HERE. 4785 03:13:23,772 --> 03:13:26,608 WE HEARD FROM COMMUNITY MEMBERS 4786 03:13:26,608 --> 03:13:28,810 REGARDING DATA SHARING, SIZE AND 4787 03:13:28,810 --> 03:13:30,545 COMPLEXITY OF DATA CAN MAKE 4788 03:13:30,545 --> 03:13:32,414 SHARING A CHALLENGE. 4789 03:13:32,414 --> 03:13:34,683 PEOPLE TOLD US ABOUT CONCERNS 4790 03:13:34,683 --> 03:13:36,217 RELATED TO PERSISTENCE OF 4791 03:13:36,217 --> 03:13:37,519 REPOSITORIES, CONCERNED ABOUT 4792 03:13:37,519 --> 03:13:39,287 WHEN I PUT EFFORT INTO 4793 03:13:39,287 --> 03:13:40,922 DEPOSITING MY DATA WITH 4794 03:13:40,922 --> 03:13:42,023 REPOSITORIES WOULD BE THERE TEN 4795 03:13:42,023 --> 03:13:44,192 YEARS FROM NOW. 4796 03:13:44,192 --> 03:13:47,829 WE HEARD ABOUT LACK OF DATA 4797 03:13:47,829 --> 03:13:49,464 STANDARDS FOR CERTAIN DATA 4798 03:13:49,464 --> 03:13:52,734 TYPES. 4799 03:13:52,734 --> 03:13:54,936 AND WE HEARD CONCERNS ABOUT 4800 03:13:54,936 --> 03:13:57,906 ALIGNING NEW OR EXISTING DOC 4801 03:13:57,906 --> 03:14:00,842 DATA REPOSITORIES WITH THE LARGE 4802 03:14:00,842 --> 03:14:01,609 NIH-WIDE DATA ECOSYSTEM. 4803 03:14:01,609 --> 03:14:05,013 WE'RE OF COURSE WELL AWARE OTHER 4804 03:14:05,013 --> 03:14:07,315 NIH INSTITUTES HAVE A LOT OF 4805 03:14:07,315 --> 03:14:09,150 ACTIVITY SIMILAR TO NIDCR IN THE 4806 03:14:09,150 --> 03:14:18,026 SPACE OF DATA SCIENCE, HOW DO WE 4807 03:14:18,026 --> 03:14:19,361 MAKE SURE (INDISCERNIBLE). 4808 03:14:19,361 --> 03:14:22,764 WORKING GROUP LOOKED AT THESE 4809 03:14:22,764 --> 03:14:24,532 COMMENTS CAREFULLY TO SYNTHESIZE 4810 03:14:24,532 --> 03:14:26,534 THESE INTO COMMON THEMES AND 4811 03:14:26,534 --> 03:14:27,502 DEVELOP OUR RECOMMENDATIONS I 4812 03:14:27,502 --> 03:14:32,007 WILL SHOW YOU LATER ON. 4813 03:14:32,007 --> 03:14:33,742 A FEW GENERAL OBSERVATIONS 4814 03:14:33,742 --> 03:14:36,177 RELATED TO THE EXISTING DOC DATA 4815 03:14:36,177 --> 03:14:37,812 ECOSYSTEM THAT INDICATE OUT. 4816 03:14:37,812 --> 03:14:42,117 THE FIRST ONE IS COMPLEXITY AND 4817 03:14:42,117 --> 03:14:42,650 HETEROGENEITY. 4818 03:14:42,650 --> 03:14:44,419 I TALKED ABOUT THIS, MANY 4819 03:14:44,419 --> 03:14:46,087 DIFFERENT TYPES OF REPOSITORY 4820 03:14:46,087 --> 03:14:46,254 THE. 4821 03:14:46,254 --> 03:14:48,156 ONE ASPECT I WANT TO HIGHLIGHT 4822 03:14:48,156 --> 03:14:51,526 WHEN WE TALK ABOUT THE DOC 4823 03:14:51,526 --> 03:14:54,396 RESEARCH COMMUNITY, THIS IS OF 4824 03:14:54,396 --> 03:14:57,132 COURSE NOT ONE COMMUNITY BUT 4825 03:14:57,132 --> 03:15:00,735 MULTIPLE USER COMMUNITIES, AND 4826 03:15:00,735 --> 03:15:02,604 THESE USER COMMUNITIES IN 4827 03:15:02,604 --> 03:15:05,874 BROADER VIEWS USE DIFFERENT 4828 03:15:05,874 --> 03:15:06,541 REPOSITORIES, DIFFERENT DATA 4829 03:15:06,541 --> 03:15:07,876 SOURCES, DIFFERENT KINDS OF USE 4830 03:15:07,876 --> 03:15:08,076 CASE. 4831 03:15:08,076 --> 03:15:13,982 THIS IS IMPORTANT TO KEEP IN 4832 03:15:13,982 --> 03:15:14,182 MIND. 4833 03:15:14,182 --> 03:15:14,883 THEN SETTING BOUNDARIES, TALKING 4834 03:15:14,883 --> 03:15:16,918 ABOUT THE MIX WE SAW IN THE 4835 03:15:16,918 --> 03:15:18,686 TYPES OF REPOSITORIES PEOPLE 4836 03:15:18,686 --> 03:15:22,290 USE, THIS CORE OF THESE 4837 03:15:22,290 --> 03:15:23,291 EXPLICITLY DOC-FOCUSED DATA 4838 03:15:23,291 --> 03:15:26,161 SYSTEMS THAT A LARGER NUMBER OF 4839 03:15:26,161 --> 03:15:28,196 SYSTEMS THAT WERE NOT EXPLICITLY 4840 03:15:28,196 --> 03:15:30,965 BUILT FOR DOC RESEARCH BUT THAT 4841 03:15:30,965 --> 03:15:32,934 CONTAIN RESEARCH THAT IS 4842 03:15:32,934 --> 03:15:35,437 RELEVANT FOR DOC -- FOR DATA 4843 03:15:35,437 --> 03:15:36,638 RELEVANT FOR DOC RESEARCHERS, 4844 03:15:36,638 --> 03:15:39,908 SOME OF THESE HEAVILY USED BY 4845 03:15:39,908 --> 03:15:43,244 DOC RESEARCHERS BUT NOT PER SE 4846 03:15:43,244 --> 03:15:46,247 YOU SEE FOCUSED DATA. 4847 03:15:46,247 --> 03:15:48,216 THE THIRD IS LACK OF 4848 03:15:48,216 --> 03:15:49,451 CONNECTIVITY. 4849 03:15:49,451 --> 03:15:50,418 SO THIS IS A PARTICULAR CASE 4850 03:15:50,418 --> 03:15:53,254 WHEN WE THINK ABOUT CONNECTIONS 4851 03:15:53,254 --> 03:15:55,356 BETWEEN DOC FOCUS WITH GENERAL 4852 03:15:55,356 --> 03:15:56,958 ASSISTANCE, NOT EVERYTHING NEEDS 4853 03:15:56,958 --> 03:15:59,360 TO BE CONNECTED TO EVERYTHING 4854 03:15:59,360 --> 03:16:02,130 ELSE BUT THERE ARE CLEARLY SOME 4855 03:16:02,130 --> 03:16:04,432 MISSED OPPORTUNITIES WHERE 4856 03:16:04,432 --> 03:16:04,933 EXISTING CONNECTIONS ARE 4857 03:16:04,933 --> 03:16:09,137 INEFFICIENT TO DO, FOR EXAMPLE, 4858 03:16:09,137 --> 03:16:11,873 INTEGRATIVE ANALYSIS OF ANY 4859 03:16:11,873 --> 03:16:13,241 KIND. 4860 03:16:13,241 --> 03:16:16,478 THEN WE HEARD CONCERNS ABOUT 4861 03:16:16,478 --> 03:16:17,245 RESOURCES AND SUPPORTING 4862 03:16:17,245 --> 03:16:18,880 MECHANISMS, THERE ARE VARIOUS 4863 03:16:18,880 --> 03:16:21,950 TYPES OF SYSTEMS OUT THERE THAT 4864 03:16:21,950 --> 03:16:23,585 ARE CURRENTLY BEING SUPPORTED 4865 03:16:23,585 --> 03:16:27,322 BUT ONE COMMENT THAT OCCURRED 4866 03:16:27,322 --> 03:16:28,723 MULTIPLE TIMES MANY ARE 4867 03:16:28,723 --> 03:16:29,724 SUPPORTED THROUGH MECHANISMS 4868 03:16:29,724 --> 03:16:34,095 THAT ARE NOT WELL ALIGNED WITH 4869 03:16:34,095 --> 03:16:34,462 SUSTAINABILITY. 4870 03:16:34,462 --> 03:16:37,932 THERE ARE MANY DATA SCIENCE 4871 03:16:37,932 --> 03:16:40,435 EFFORTS THAT ARE SUPPORTED 4872 03:16:40,435 --> 03:16:43,605 THROUGH RESEARCH GRANT TYPES OF 4873 03:16:43,605 --> 03:16:46,674 SUPPORT, AND THIS RAISES 4874 03:16:46,674 --> 03:16:47,876 QUESTIONS FOR THE 4875 03:16:47,876 --> 03:16:48,810 SUSTAINABILITY, LONGEVITY OF 4876 03:16:48,810 --> 03:16:50,845 DATA AND RESOURCES THAT ARE 4877 03:16:50,845 --> 03:16:53,381 BEING BUILT. 4878 03:16:53,381 --> 03:16:54,883 AND THEN FINALLY, THIS IS 4879 03:16:54,883 --> 03:16:58,720 ESSENTIALLY A COMBINATION OF 4880 03:16:58,720 --> 03:17:00,255 SOME OTHER FACTORS, FOR FAIR 4881 03:17:00,255 --> 03:17:01,022 COMPLIANCE, MOST PEOPLE IN THE 4882 03:17:01,022 --> 03:17:02,657 COMMUNITY AT THIS POINT ARE 4883 03:17:02,657 --> 03:17:07,362 DEDICATED TO THE IDEA OF FAIR, 4884 03:17:07,362 --> 03:17:09,030 MAKING DATA FINDABLE, 4885 03:17:09,030 --> 03:17:13,735 ACCESSIBLE, INTRAOPERABLE AND 4886 03:17:13,735 --> 03:17:17,372 REUSABLE BUT SOME FACTORS CAN 4887 03:17:17,372 --> 03:17:18,273 CREATE HURDLES. 4888 03:17:18,273 --> 03:17:22,744 SO, LET ME TALK SOME MORE ABOUT 4889 03:17:22,744 --> 03:17:26,881 OPPORTUNITIES IN DATA SCIENCE. 4890 03:17:26,881 --> 03:17:30,485 SO OBVIOUSLY, DATA SCIENCE HAS 4891 03:17:30,485 --> 03:17:31,152 FORMATIVE POTENTIAL IN 4892 03:17:31,152 --> 03:17:34,088 BIOMEDICAL RESEARCH IN GENERAL. 4893 03:17:34,088 --> 03:17:37,158 WE THOUGHT ABOUT THE DOC SPACE 4894 03:17:37,158 --> 03:17:37,792 IN PARTICULAR. 4895 03:17:37,792 --> 03:17:40,995 WHAT ARE AREAS WHERE WE SEE 4896 03:17:40,995 --> 03:17:43,831 POTENTIAL BIGGEST IMPACT FOR 4897 03:17:43,831 --> 03:17:49,304 DATA SCIENCE BASED APPROACHES IN 4898 03:17:49,304 --> 03:17:50,171 ADVANCING NIDCR MISSION. 4899 03:17:50,171 --> 03:17:54,108 AND FOUR BIG AREAS WE IDENTIFIED 4900 03:17:54,108 --> 03:17:58,913 HERE ARE OPPORTUNITIES IN 4901 03:17:58,913 --> 03:18:00,548 ADDRESSING HEALTH DISPARITIES, 4902 03:18:00,548 --> 03:18:02,150 MITIGATING THEM, UNDERSTANDING 4903 03:18:02,150 --> 03:18:03,718 THE CAUSES. 4904 03:18:03,718 --> 03:18:07,322 THE SECOND RELATES TO ARTIFICIAL 4905 03:18:07,322 --> 03:18:09,224 INTELLIGENCE AND MACHINE 4906 03:18:09,224 --> 03:18:09,557 LEARNING. 4907 03:18:09,557 --> 03:18:15,430 MAKING SURE THAT DOC RESEARCHERS 4908 03:18:15,430 --> 03:18:17,098 LEVERAGE NEW TOOLS, RELATED TO 4909 03:18:17,098 --> 03:18:20,935 THAT MAKE SURE A DOC DATA AND 4910 03:18:20,935 --> 03:18:25,940 NEW DOC DATA SCIENCE EFFORTS ARE 4911 03:18:25,940 --> 03:18:27,809 COMPATIBLE AND REALLY FACILITATE 4912 03:18:27,809 --> 03:18:29,344 THE READINESS OF THE DATA THAT 4913 03:18:29,344 --> 03:18:33,881 WE PUT IN THERE FOR ANALYSIS, 4914 03:18:33,881 --> 03:18:37,151 USING THESE INNOVATIVE 4915 03:18:37,151 --> 03:18:37,585 APPROACHES. 4916 03:18:37,585 --> 03:18:41,756 THIRD RELATES TO USING DATA 4917 03:18:41,756 --> 03:18:42,957 SCIENCE TO ACCELERATE 4918 03:18:42,957 --> 03:18:44,359 APPLICATIONS, RIGHT? 4919 03:18:44,359 --> 03:18:46,995 AND WE HEARD IN RENA'S 4920 03:18:46,995 --> 03:18:48,196 PRESENTATION EARLIER THIS 4921 03:18:48,196 --> 03:18:50,598 ACRONYM, DDS, IN THAT CASE 4922 03:18:50,598 --> 03:18:51,466 STANDS FOR DATA-DRIVEN 4923 03:18:51,466 --> 03:18:54,869 SOLUTIONS, SO THIS RELATES TO 4924 03:18:54,869 --> 03:18:57,338 THAT, APPLICATIONS FOR DATA 4925 03:18:57,338 --> 03:19:02,477 SCIENCE CAN HELP DEVELOP 4926 03:19:02,477 --> 03:19:04,979 APPLICATIONS IN DOC SPACE. 4927 03:19:04,979 --> 03:19:06,314 FINALLY DATA DIVERSITY. 4928 03:19:06,314 --> 03:19:13,521 IT IS A CHALLENGE, BUT MORE 4929 03:19:13,521 --> 03:19:17,892 OPPORTUNITIES ARISE FROM THAT. 4930 03:19:17,892 --> 03:19:19,761 THE FIRST IS ORAL HEALTH 4931 03:19:19,761 --> 03:19:20,595 DISPARITIES. 4932 03:19:20,595 --> 03:19:22,263 WE HEARD IN THIS COUNCIL, IN 4933 03:19:22,263 --> 03:19:23,464 EVERY SINGLE LAST COUNCIL 4934 03:19:23,464 --> 03:19:27,302 SESSION, ABOUT THIS BEING A TOP 4935 03:19:27,302 --> 03:19:30,672 PRIORITY FOR NIDCR, AND FOR NIH 4936 03:19:30,672 --> 03:19:31,973 IN GENERAL. 4937 03:19:31,973 --> 03:19:37,245 WE THINK THERE ARE MULTIPLE 4938 03:19:37,245 --> 03:19:39,013 AREAS IN THE DOC RESEARCH SPACE 4939 03:19:39,013 --> 03:19:39,981 DATA SCIENCES THAT MAJOR 4940 03:19:39,981 --> 03:19:40,615 OPPORTUNITIES. 4941 03:19:40,615 --> 03:19:43,918 FIVE BIG AREAS WE WANT TO CALL 4942 03:19:43,918 --> 03:19:47,088 OUT ARE INTEGRATION OF SOCIAL 4943 03:19:47,088 --> 03:19:49,724 DETERMINANTS INTO POPULATION 4944 03:19:49,724 --> 03:19:55,563 HEALTH STUDIES, AND POPULATION 4945 03:19:55,563 --> 03:19:56,297 ORAL HEALTH STUDIES. 4946 03:19:56,297 --> 03:19:57,398 DEVELOPMENT OF BETTER METHODS 4947 03:19:57,398 --> 03:19:59,033 FOR ANALYZING THIS TYPE OF 4948 03:19:59,033 --> 03:20:01,869 POPULATION DATA TO BOTH 4949 03:20:01,869 --> 03:20:04,038 UNDERSTAND THE CAUSES OF ORAL 4950 03:20:04,038 --> 03:20:06,908 HEALTH DISPARITIES BUT ALSO TO 4951 03:20:06,908 --> 03:20:10,778 DEVELOP AND PREDICT OUTCOMES OF 4952 03:20:10,778 --> 03:20:16,250 POSSIBLE SOLUTIONS, POSSIBLE 4953 03:20:16,250 --> 03:20:18,086 IMPLICATIONS OF POLICY CHANGES 4954 03:20:18,086 --> 03:20:20,955 OPPORTUNITIES THAT ARISE FROM 4955 03:20:20,955 --> 03:20:26,527 COMBINING DATA ECOSYSTEMS, 4956 03:20:26,527 --> 03:20:27,161 INCREASING INTEROPERABILITY IN 4957 03:20:27,161 --> 03:20:29,731 THE DOC SPACE BUT IMPORTANTLY 4958 03:20:29,731 --> 03:20:33,101 BEYOND THE DOC SPACE. 4959 03:20:33,101 --> 03:20:33,868 THIS DIRECTLY RELATES TO SOCIAL 4960 03:20:33,868 --> 03:20:36,471 DETERMINANTS OF HEALTH. 4961 03:20:36,471 --> 03:20:37,805 THEN WORKFORCE DEVELOPMENT IS 4962 03:20:37,805 --> 03:20:40,775 AGAIN A TOPIC THAT IS HIGH ON 4963 03:20:40,775 --> 03:20:42,043 THE NIDCR PRIORITY LIST. 4964 03:20:42,043 --> 03:20:43,411 WE JUST HEARD FROM THE OTHER 4965 03:20:43,411 --> 03:20:45,146 WORKING GROUP THAT IS 4966 03:20:45,146 --> 03:20:46,981 SPECIFICALLY FOCUSED ON THIS. 4967 03:20:46,981 --> 03:20:50,184 WE BELIEVE THAT THERE ARE IN THE 4968 03:20:50,184 --> 03:20:52,687 AREA OF DATA SCIENCE AND IN 4969 03:20:52,687 --> 03:20:56,391 PARTICULAR IN THIS AREA OF DATA 4970 03:20:56,391 --> 03:20:58,793 SCIENCE FOR POPULATION HEALTH 4971 03:20:58,793 --> 03:21:01,896 RESEARCH, MAJOR GAPS RIGHT NOW 4972 03:21:01,896 --> 03:21:03,831 THAT CAN BE ADDRESSED. 4973 03:21:03,831 --> 03:21:06,934 AND FIFTH SET OF OPPORTUNITIES 4974 03:21:06,934 --> 03:21:17,445 RELATES TO MONITORING OF A.I. 4975 03:21:18,479 --> 03:21:19,914 APPLICATIONS. 4976 03:21:19,914 --> 03:21:22,683 MORE DETAIL, FIRST IS 4977 03:21:22,683 --> 03:21:23,851 INTEGRATION OF DETERMINANTS. 4978 03:21:23,851 --> 03:21:27,054 YOU HEARD ABOUT THIS EARLIER 4979 03:21:27,054 --> 03:21:28,055 TODAY. 4980 03:21:28,055 --> 03:21:29,457 YOU KNOW, SO THERE ARE MULTIPLE 4981 03:21:29,457 --> 03:21:32,393 LAYERS OF ISSUES HERE. 4982 03:21:32,393 --> 03:21:35,396 SO, ONE IS THAT WE OF COURSE 4983 03:21:35,396 --> 03:21:40,067 KNOW THAT IN THE EXISTING DATA 4984 03:21:40,067 --> 03:21:43,571 THAT WE HAVE AVAILABLE, RIGHT 4985 03:21:43,571 --> 03:21:45,973 NOW, THERE ARE CLEARLY BIASES, 4986 03:21:45,973 --> 03:21:48,142 IN THE ESSENTIAL THAT 4987 03:21:48,142 --> 03:21:50,344 DISADVANTAGED POPULATIONS TEND 4988 03:21:50,344 --> 03:21:51,446 TO BE UNDERREPRESENTED IN THE 4989 03:21:51,446 --> 03:21:52,547 EXISTING DATA. 4990 03:21:52,547 --> 03:21:56,284 WE HEARD ABOUT THE "ALL OF US" 4991 03:21:56,284 --> 03:21:58,019 PROJECT AS AN EFFORT THAT WILL 4992 03:21:58,019 --> 03:21:58,920 COLLECT MORE REPRESENTATIVE DATA 4993 03:21:58,920 --> 03:22:02,423 BUT THERE'S A LARGE AMOUNT OF 4994 03:22:02,423 --> 03:22:03,391 PREEXISTING DATA THAT IS 4995 03:22:03,391 --> 03:22:06,794 PRINCIPALLY USEFUL FOR THESE 4996 03:22:06,794 --> 03:22:09,430 TYPES OF STUDIES BUT MAY CONTAIN 4997 03:22:09,430 --> 03:22:10,731 MAJOR BIAS. 4998 03:22:10,731 --> 03:22:14,535 WE ALSO HEARD ABOUT THE 4999 03:22:14,535 --> 03:22:16,637 IMPORTANCE OF INTEGRATION OF 5000 03:22:16,637 --> 03:22:21,008 OTHER TYPES OF DATA, SOCIAL 5001 03:22:21,008 --> 03:22:22,777 DETERMINANTS, ALSO HEARD ABOUT 5002 03:22:22,777 --> 03:22:25,713 GEOSPATIAL DATA AND OTHER 5003 03:22:25,713 --> 03:22:28,916 ENVIRONMENTAL DATA IN THE 5004 03:22:28,916 --> 03:22:30,785 PRESENTATION BY RICK I WOULD 5005 03:22:30,785 --> 03:22:31,752 CHECK EARLIER TODAY, SOMETHING 5006 03:22:31,752 --> 03:22:33,855 THAT SEEMS IMPORTANT THAT WE 5007 03:22:33,855 --> 03:22:35,923 LEVERAGE DATA SCIENCE TO REALLY 5008 03:22:35,923 --> 03:22:39,293 GO FROM STUDIES THAT LOOK AT 5009 03:22:39,293 --> 03:22:41,929 JUST ONE SINGLE FACTOR AT A 5010 03:22:41,929 --> 03:22:46,868 TIME, AND TAKE A HOLISTIC VIEW 5011 03:22:46,868 --> 03:22:47,969 INTEGRATING THE PROCESS AND 5012 03:22:47,969 --> 03:22:49,136 SOCIAL TIMES OF DATASETS WITH 5013 03:22:49,136 --> 03:22:50,471 HEALTH DATA. 5014 03:22:50,471 --> 03:22:52,540 WHAT WE NEED FOR THAT TWO 5015 03:22:52,540 --> 03:22:54,942 THINGS, FIRST IS THE 5016 03:22:54,942 --> 03:22:57,879 METHODOLOGICAL ENHANCEMENT. 5017 03:22:57,879 --> 03:23:01,315 WE NEED BETTER METHODS TO REALLY 5018 03:23:01,315 --> 03:23:03,718 ADDRESS SUCH COMPLEX DATASETS. 5019 03:23:03,718 --> 03:23:05,786 UNDERSTAND BETTER WHAT THE EXACT 5020 03:23:05,786 --> 03:23:08,689 CAUSES OF ORAL HEALTH 5021 03:23:08,689 --> 03:23:12,627 DISPARITIES EVEN ARE, AND THEN 5022 03:23:12,627 --> 03:23:14,262 USING THIS TO DEVELOP SOLUTIONS 5023 03:23:14,262 --> 03:23:23,571 THAT CAN BE USED TO MITIGATE. 5024 03:23:23,571 --> 03:23:25,439 THE OTHER THING NEEDED IS 5025 03:23:25,439 --> 03:23:30,177 MERGING DOC DATA WITH BROADER 5026 03:23:30,177 --> 03:23:31,679 DATA, AND THIS REQUIRES SOME OF 5027 03:23:31,679 --> 03:23:33,447 THESE NEW CONNECTIONS THAT I 5028 03:23:33,447 --> 03:23:34,649 TALKED ABOUT IN THE EARLIER 5029 03:23:34,649 --> 03:23:37,051 SLIDE THAT WE FEET ARE STILL 5030 03:23:37,051 --> 03:23:42,156 MISSING IN MANY CASES. 5031 03:23:42,156 --> 03:23:46,494 IF DONE RIGHT, THIS WILL ENABLE 5032 03:23:46,494 --> 03:23:49,096 ADVANCED METHODS FOR ANALYSIS 5033 03:23:49,096 --> 03:23:52,633 AND DEVELOPING BETTER HEALTH 5034 03:23:52,633 --> 03:23:54,368 POLICY TO ADDRESS DISPARITIES. 5035 03:23:54,368 --> 03:23:55,937 WORKFORCE DEVELOPMENT IS REALLY 5036 03:23:55,937 --> 03:23:57,872 IMPORTANT, AND THERE ARE TWO 5037 03:23:57,872 --> 03:23:58,406 ASPECTS. 5038 03:23:58,406 --> 03:24:01,609 ONE IS OF COURSE DIVERSIFICATION 5039 03:24:01,609 --> 03:24:02,677 OF THE WORKFORCE, I DON'T THINK 5040 03:24:02,677 --> 03:24:04,845 I NEED TO CONVINCE ANYONE HERE 5041 03:24:04,845 --> 03:24:07,415 WE NEED A MORE DIVERSE WORKFORCE 5042 03:24:07,415 --> 03:24:10,318 IF WE WANT TO ADDRESS UNDERLYING 5043 03:24:10,318 --> 03:24:13,821 CAUSES OF CURRENT HEALTH 5044 03:24:13,821 --> 03:24:14,388 DISPARITIES. 5045 03:24:14,388 --> 03:24:16,724 BUT THEN ALSO SPECIFICALLY WITH 5046 03:24:16,724 --> 03:24:19,026 RESPECT TO DATA SCIENCE, WE FEEL 5047 03:24:19,026 --> 03:24:24,599 THERE IS A NEED FOR BETTER 5048 03:24:24,599 --> 03:24:25,900 TRAINING, SPECIFICALLY FOR 5049 03:24:25,900 --> 03:24:27,101 RESEARCHERS, SPECIALIZING IN 5050 03:24:27,101 --> 03:24:31,606 APPLICATIONS OF DATA SCIENCE TO 5051 03:24:31,606 --> 03:24:32,473 DOC POPULATION RESEARCH, THERE'S 5052 03:24:32,473 --> 03:24:35,443 AN OPPORTUNITY TO BUILD A 5053 03:24:35,443 --> 03:24:37,645 PIPELINE OF RESEARCHERS THAT 5054 03:24:37,645 --> 03:24:39,714 HAVE EXPERTISE, INTERESTS, AND 5055 03:24:39,714 --> 03:24:43,551 TRAINING IN DOING THIS WORK, BUT 5056 03:24:43,551 --> 03:24:44,652 THIS PIPELINE CURRENTLY DOESN'T 5057 03:24:44,652 --> 03:24:45,386 EXIST. 5058 03:24:45,386 --> 03:24:48,255 AND FINALLY I WILL TALK ABOUT 5059 03:24:48,255 --> 03:24:51,092 A.I. MORE IN A MOMENT AS A WHOLE 5060 03:24:51,092 --> 03:24:52,059 SET, BUT SPECIFICALLY WITH 5061 03:24:52,059 --> 03:24:54,261 RESPECT TO ORAL HEALTH 5062 03:24:54,261 --> 03:24:57,765 DISPARITIES, SOMETHING THAT CAME 5063 03:24:57,765 --> 03:25:01,268 UP AS AN IMPORTANT CONSIDERATION 5064 03:25:01,268 --> 03:25:04,639 IS THE ISSUE OF ETHICAL A.I. USE 5065 03:25:04,639 --> 03:25:06,540 AND A.I. MONITORING. 5066 03:25:06,540 --> 03:25:08,509 THIS IS SOMETHING THAT HAS BEEN 5067 03:25:08,509 --> 03:25:13,047 OBSERVED NOT JUST IN THE 5068 03:25:13,047 --> 03:25:13,814 BIOMEDICAL SPACE, LARGE 5069 03:25:13,814 --> 03:25:14,315 COMPANIES THAT DO. 5070 03:25:14,315 --> 03:25:18,052 A I SPEND EFFORT MAKING SURE 5071 03:25:18,052 --> 03:25:19,787 A.I. IS BEHAVING ETHICAL, 5072 03:25:19,787 --> 03:25:22,156 SOMETHING WELL UNDERSTOOD IS 5073 03:25:22,156 --> 03:25:25,660 THAT MANY OF THESE APPROACHES 5074 03:25:25,660 --> 03:25:26,861 ESSENTIALLY REFLECT THE DATA 5075 03:25:26,861 --> 03:25:28,062 THAT YOU FEED THEM. 5076 03:25:28,062 --> 03:25:30,898 THE PROBLEM IS THAT WITH MANY 5077 03:25:30,898 --> 03:25:32,199 TYPES OF DATASETS, MIGHT BE DATA 5078 03:25:32,199 --> 03:25:34,468 THAT YOU FIND GENERALLY ON THE 5079 03:25:34,468 --> 03:25:39,206 INTERNET FOR GENERAL A.I. 5080 03:25:39,206 --> 03:25:41,709 ENGINE, OR IN THE BIOMEDICAL 5081 03:25:41,709 --> 03:25:43,144 SPACE WE HAVE BIAS AND SKEWED 5082 03:25:43,144 --> 03:25:45,579 DATA WE FEED INTO SYSTEMS THAT 5083 03:25:45,579 --> 03:25:48,516 SOME OF THESE PREEXISTING BIASES 5084 03:25:48,516 --> 03:25:50,551 MAY BE NOT JUST REFLECTED BUT 5085 03:25:50,551 --> 03:25:52,653 EVEN AMPLIFIED BY A.I. SYSTEMS 5086 03:25:52,653 --> 03:25:56,824 THAT HAVE BEEN TRAINED ON BIASED 5087 03:25:56,824 --> 03:25:57,024 DATA. 5088 03:25:57,024 --> 03:26:01,295 SO, THIS ASPECT IS REALLY 5089 03:26:01,295 --> 03:26:02,496 IMPORTANT TO KIND IN MIND, THE 5090 03:26:02,496 --> 03:26:04,365 NEED TO BE ACTIVE IN EFFORTS TO 5091 03:26:04,365 --> 03:26:09,203 MAKE SURE ANY APPLICATIONS OF A. 5092 03:26:09,203 --> 03:26:11,906 I. IN THE DOC SPACE ARE 5093 03:26:11,906 --> 03:26:12,773 ADDRESSING THIS. 5094 03:26:12,773 --> 03:26:14,008 THERE ARE OPPORTUNITIES HERE. 5095 03:26:14,008 --> 03:26:16,544 YOU CAN USE A.I. FOR EXAMPLE TO 5096 03:26:16,544 --> 03:26:18,979 ADDRESS SUCH SKEWS, BUT AS WE 5097 03:26:18,979 --> 03:26:20,481 DEVELOP APPLICATIONS WE NEED TO 5098 03:26:20,481 --> 03:26:23,584 TAKE THESE BIASES INTO 5099 03:26:23,584 --> 03:26:24,018 CONSIDERATION. 5100 03:26:24,018 --> 03:26:25,653 THIS WILL REQUIRE A LOT OF 5101 03:26:25,653 --> 03:26:27,321 EFFORT IN DEVELOPING SUCH 5102 03:26:27,321 --> 03:26:29,924 APPLICATIONS IN THE FIRST PLACE, 5103 03:26:29,924 --> 03:26:32,326 BUT IT WILL ALSO REQUIRE 5104 03:26:32,326 --> 03:26:34,061 CONTINUOUS MONITORING OF THESE 5105 03:26:34,061 --> 03:26:36,363 APPROACHES AS THEY ARE BEING 5106 03:26:36,363 --> 03:26:37,131 DEPLOYED AND FURTHER DEVELOPED, 5107 03:26:37,131 --> 03:26:43,571 AND THIS WILL BE PARTICULAR WILL 5108 03:26:43,571 --> 03:26:46,440 IMPORTANT IF ANY APPROACHES 5109 03:26:46,440 --> 03:26:49,410 GUIDE POLICY DECISIONS, ETHICAL 5110 03:26:49,410 --> 03:26:52,012 A.I. USE. 5111 03:26:52,012 --> 03:26:56,083 AND WITH THIS, I'LL SEGUE INTO 5112 03:26:56,083 --> 03:26:58,786 THE BROADER SECOND SET OF 5113 03:26:58,786 --> 03:27:00,688 OPPORTUNITIES IDENTIFIED. 5114 03:27:00,688 --> 03:27:04,859 MORE GENERALLY A.I. ML AND 5115 03:27:04,859 --> 03:27:07,061 A.I./ML READINESS OF DOC DATA. 5116 03:27:07,061 --> 03:27:16,137 ON THIS SLIDE YOU SEE SUBSET OF 5117 03:27:16,137 --> 03:27:17,772 POSSIBLE APPLICATIONS WE FEEL 5118 03:27:17,772 --> 03:27:20,274 AI/MACHINE LEARNING AND DEEP 5119 03:27:20,274 --> 03:27:20,808 LEARNING, NATURAL LANGUAGE 5120 03:27:20,808 --> 03:27:22,877 PROCESSING AND SO ON COULD HAVE 5121 03:27:22,877 --> 03:27:30,050 A MAJOR IMPACT IN ADVANCING DOC 5122 03:27:30,050 --> 03:27:30,584 RESEARCH. 5123 03:27:30,584 --> 03:27:31,786 THESE INCLUDE INTEGRATION ACROSS 5124 03:27:31,786 --> 03:27:32,987 MULTI-MODAL DATA TYPES, ANALYSIS 5125 03:27:32,987 --> 03:27:37,992 OF LARGE AND COMPLEX DATASETS, 5126 03:27:37,992 --> 03:27:39,426 GENETICS AND GENOMICS, TYPICALLY 5127 03:27:39,426 --> 03:27:40,728 DEALING WITH DATASETS THAT 5128 03:27:40,728 --> 03:27:44,365 CANNOT BE ANALYZED BY HUMANS. 5129 03:27:44,365 --> 03:27:46,767 AT LEAST NOT IN A REASONABLE 5130 03:27:46,767 --> 03:27:47,067 MANNER. 5131 03:27:47,067 --> 03:27:47,835 NATURAL LANGUAGE PROCESSING HAS 5132 03:27:47,835 --> 03:27:48,736 COME A LONG WAY. 5133 03:27:48,736 --> 03:27:52,439 THIS CAN BE USED IN MANY WAYS. 5134 03:27:52,439 --> 03:27:57,178 IT CAN BE USED TO ACCELERATE 5135 03:27:57,178 --> 03:27:59,647 RESEARCH BY APPLYING FOR 5136 03:27:59,647 --> 03:28:00,414 ANALYSIS AND INTERPRETATION 5137 03:28:00,414 --> 03:28:01,515 LITERATURE BUT IN THE CLINICAL 5138 03:28:01,515 --> 03:28:06,220 SPACE CAN ALSO BE USED TO 5139 03:28:06,220 --> 03:28:08,088 ANALYZE PATIENT RECORDS, TO 5140 03:28:08,088 --> 03:28:10,491 TRANSFORM FREE TEXT ENTRIES, FOR 5141 03:28:10,491 --> 03:28:12,359 EXAMPLE, INTO STANDARDIZED 5142 03:28:12,359 --> 03:28:18,499 FORMAT TO FEED INTO MORE 5143 03:28:18,499 --> 03:28:19,366 AUTOMATED DATA SCIENCE 5144 03:28:19,366 --> 03:28:19,967 PROCESSES. 5145 03:28:19,967 --> 03:28:23,404 A.I. IS GOOD AT ANALYZING IMAGE 5146 03:28:23,404 --> 03:28:26,373 DATA, 2D AND 3D DATA FOR 5147 03:28:26,373 --> 03:28:27,575 DETECTION AND DIAGNOSIS. 5148 03:28:27,575 --> 03:28:30,211 A.I. IS GOOD FOR INTEGRATING 5149 03:28:30,211 --> 03:28:31,412 ACROSS DATASETS, AND ONE 5150 03:28:31,412 --> 03:28:33,781 IMPORTANT APPLICATION FOR THIS I 5151 03:28:33,781 --> 03:28:34,248 TALKED ABOUT ALREADY, 5152 03:28:34,248 --> 03:28:36,550 INTEGRATING PUBLIC HEALTH DATA 5153 03:28:36,550 --> 03:28:39,620 WITH OTHER NON-MEDICAL TYPE OF 5154 03:28:39,620 --> 03:28:40,254 DATA. 5155 03:28:40,254 --> 03:28:41,155 DEMOGRAPHICS, SOCIOECONOMIC, 5156 03:28:41,155 --> 03:28:44,358 GEOGRAPHIC AND OTHER COMPLEX 5157 03:28:44,358 --> 03:28:45,125 DATA TYPES. 5158 03:28:45,125 --> 03:28:49,363 CAN BE USED FOR PREDICTIVE 5159 03:28:49,363 --> 03:28:49,630 MODELING. 5160 03:28:49,630 --> 03:28:51,565 I MENTION PREDICTIVE PATIENT 5161 03:28:51,565 --> 03:28:53,100 OUTCOMES, ALSO PREDICTIVE 5162 03:28:53,100 --> 03:28:55,870 MODELING OF POLICY DECISION. 5163 03:28:55,870 --> 03:28:58,005 DEVELOPMENT OF PERSONALIZED 5164 03:28:58,005 --> 03:29:00,107 TREATMENT PLANS, SO ASSISTING IN 5165 03:29:00,107 --> 03:29:00,741 CLINICAL CARE. 5166 03:29:00,741 --> 03:29:02,877 GENERATIVE A.I. IS IMPORTANT, SO 5167 03:29:02,877 --> 03:29:06,447 YOU CAN USE IT TO MAKE 5168 03:29:06,447 --> 03:29:10,484 NICE-LOOKING IMAGES BUT ALSO USE 5169 03:29:10,484 --> 03:29:13,954 IT, FOR EXAMPLE, TO OPTIMIZE 5170 03:29:13,954 --> 03:29:15,856 DEVICES, IMPLANTS, SCAFFOLDS, TO 5171 03:29:15,856 --> 03:29:16,490 GUIDE MATERIAL SELECTION. 5172 03:29:16,490 --> 03:29:19,026 IT CAN BE USED TO ANALYZE 5173 03:29:19,026 --> 03:29:20,761 PATIENT BEHAVIOR DATA IN REAL 5174 03:29:20,761 --> 03:29:21,228 TIME. 5175 03:29:21,228 --> 03:29:25,032 OR CAN BE USED FOR ENHANCED 5176 03:29:25,032 --> 03:29:25,499 TELEDENTISTRY. 5177 03:29:25,499 --> 03:29:27,368 THIS IS A LONG LIST, PROBABLY 5178 03:29:27,368 --> 03:29:30,304 THERE ARE QUITE A FEW MORE ONE 5179 03:29:30,304 --> 03:29:31,071 CAN THINK OF AND BECOME 5180 03:29:31,071 --> 03:29:32,039 IMPORTANT IN FUTURE YEARS. 5181 03:29:32,039 --> 03:29:36,076 WITH ALL OF THIS IN MIND, THERE 5182 03:29:36,076 --> 03:29:37,411 IS A NUMBER OF REQUIREMENTS TO 5183 03:29:37,411 --> 03:29:39,613 KEEP IN MIND. 5184 03:29:39,613 --> 03:29:41,448 THESE ARE IMPORTANT FOR DRIVING 5185 03:29:41,448 --> 03:29:44,618 WHAT WE THINK IS IMPORTANT FOR 5186 03:29:44,618 --> 03:29:47,588 NIDCR TO DO TO THINK ABOUT THE 5187 03:29:47,588 --> 03:29:49,990 FUTURE OF DOC DATA. 5188 03:29:49,990 --> 03:29:53,360 REQUIREMENTS TO ACHIEVE A.I. IN 5189 03:29:53,360 --> 03:29:55,696 DATA SYSTEMS, INCLUDE FIRST OF 5190 03:29:55,696 --> 03:29:58,232 ALL RIGOROUS SYSTEM FOR DATA 5191 03:29:58,232 --> 03:30:00,935 GOVERNANCE AND EQUITABLE 5192 03:30:00,935 --> 03:30:01,936 CURATION. 5193 03:30:01,936 --> 03:30:03,370 SO, THIS IS PARTICULARLY 5194 03:30:03,370 --> 03:30:05,673 IMPORTANT FOR CLINICAL DATA 5195 03:30:05,673 --> 03:30:06,974 WHERE WE NEED TO DEAL WITH OR 5196 03:30:06,974 --> 03:30:10,144 ANY OTHER DATA WHERE WE NEED TO 5197 03:30:10,144 --> 03:30:13,647 DEAL WITH INTELLECTUAL PROPERTY, 5198 03:30:13,647 --> 03:30:15,082 LIKE PATIENT-RELATED 5199 03:30:15,082 --> 03:30:18,018 INFORMATION, HIPAA COMPLIANCE, 5200 03:30:18,018 --> 03:30:18,352 RIGHT? 5201 03:30:18,352 --> 03:30:19,753 SYSTEMS ARE NOTORIOUSLY KEEPING 5202 03:30:19,753 --> 03:30:20,721 THE DATA CONFINED, MANY WORK 5203 03:30:20,721 --> 03:30:23,257 KIND OF LIKE BLACK BOXES. 5204 03:30:23,257 --> 03:30:26,760 REALLY WE NEED TO MAKE SURE DATA 5205 03:30:26,760 --> 03:30:28,829 GOVERNANCE GOES INTO THESE 5206 03:30:28,829 --> 03:30:31,799 SYSTEMS AND PROPAGATED THROUGH 5207 03:30:31,799 --> 03:30:32,900 THESE SYSTEMS. 5208 03:30:32,900 --> 03:30:34,201 TYPICALLY ANY OF THESE 5209 03:30:34,201 --> 03:30:35,402 APPROACHES, NO MATTER HOW SMART, 5210 03:30:35,402 --> 03:30:38,138 ARE ONLY AS GOOD AS THE DATA 5211 03:30:38,138 --> 03:30:41,308 THAT GOES INTO THEM. 5212 03:30:41,308 --> 03:30:45,145 AND SO ANOTHER IMPORTANT ASPECT 5213 03:30:45,145 --> 03:30:49,717 TO ACHIEVE AI/ML READINESS IS 5214 03:30:49,717 --> 03:30:51,719 STRINGENT DATA QUALITY STANDARDS 5215 03:30:51,719 --> 03:30:53,487 INCLUDING DEVELOPMENT OF QUALITY 5216 03:30:53,487 --> 03:30:55,823 METRICS, ALSO REQUIRES A LOT OF 5217 03:30:55,823 --> 03:31:00,928 EFFORT FOR DATASETS IN TERMS OF 5218 03:31:00,928 --> 03:31:01,762 CLEANING NORMALIZATION, 5219 03:31:01,762 --> 03:31:02,463 LABELING, ANNOTATION OF DATA TO 5220 03:31:02,463 --> 03:31:10,137 MAKE SURE WHEN IT GETS ANALYZED 5221 03:31:10,137 --> 03:31:11,772 YOU GET DISCERN. 5222 03:31:11,772 --> 03:31:15,075 AND DATA INTEGRATION, WE CAN USE 5223 03:31:15,075 --> 03:31:16,810 THESE APPROACHES TO INTEGRATE 5224 03:31:16,810 --> 03:31:18,012 MULTI-MODAL DATA FROM SOURCES 5225 03:31:18,012 --> 03:31:21,215 BUT IN ORDER TO DO SO IT IS 5226 03:31:21,215 --> 03:31:23,617 IMPORTANT DATA ARE COMPATIBLE 5227 03:31:23,617 --> 03:31:25,452 WHICH REQUIRES HARMONIZATION OF 5228 03:31:25,452 --> 03:31:27,221 DATA FOR INTEGRATION ACROSS 5229 03:31:27,221 --> 03:31:27,454 STUDIES. 5230 03:31:27,454 --> 03:31:29,823 THIS REQUIRES THINGS SUCH AS 5231 03:31:29,823 --> 03:31:33,027 DATA STANDARDS, DATA ONTOLOGIES, 5232 03:31:33,027 --> 03:31:34,862 SO ON. 5233 03:31:34,862 --> 03:31:37,297 THE FOURTH CHARACTERISTIC OF 5234 03:31:37,297 --> 03:31:47,808 AI/ML IS THAT IT CAN SUPPORT 5235 03:31:52,446 --> 03:31:54,548 HIGHLY SKILLED SCALABLE, 5236 03:31:54,548 --> 03:31:55,682 HANDLING LARGE VOLUMES IN REAL 5237 03:31:55,682 --> 03:31:56,216 TIME. 5238 03:31:56,216 --> 03:32:02,156 MANY OF THESE A.I. APPLICATIONS 5239 03:32:02,156 --> 03:32:04,758 ARE VERY COMPUTE INTENSIVE, DATA 5240 03:32:04,758 --> 03:32:06,727 INFRASTRUCTURE NEEDS TO SCALE 5241 03:32:06,727 --> 03:32:10,664 FOR VELOCITY, SO SPEED IF WE 5242 03:32:10,664 --> 03:32:11,965 NEED TO MAKE APPLICATIONS. 5243 03:32:11,965 --> 03:32:13,067 AND THE LAST ONE, THIS RELATES 5244 03:32:13,067 --> 03:32:15,269 BACK TO THE FIRST ONE A LITTLE 5245 03:32:15,269 --> 03:32:17,337 BIT, IS DATA SECURITY AND 5246 03:32:17,337 --> 03:32:17,638 COMPLIANCE. 5247 03:32:17,638 --> 03:32:24,978 WE NEED TO MAKE SURE THAT IP, 5248 03:32:24,978 --> 03:32:25,979 HIPAA COMPLIANCE, PATIENT DATA 5249 03:32:25,979 --> 03:32:29,683 IS SECURE IN THESE SYSTEMS. 5250 03:32:29,683 --> 03:32:31,785 AND I THINK FOR A.I. SPACE THIS 5251 03:32:31,785 --> 03:32:34,154 IS IN SOME AREAS STILL AN 5252 03:32:34,154 --> 03:32:34,555 UNSOLVED PROBLEM. 5253 03:32:34,555 --> 03:32:37,357 WE NEED TO MAKE SURE THAT THERE 5254 03:32:37,357 --> 03:32:40,894 ARE ROBUST STANDARDS AND 5255 03:32:40,894 --> 03:32:42,963 MECHANISMS FOR DATA SECURITY, 5256 03:32:42,963 --> 03:32:44,598 COMPLIANCE WITH ALL REGULATION, 5257 03:32:44,598 --> 03:32:46,900 AND THIS IN TURN REQUIRES 5258 03:32:46,900 --> 03:32:49,970 DEVELOPMENT OF PROTOCOL FOR 5259 03:32:49,970 --> 03:32:50,504 ACCESS, ENCRYPTION, 5260 03:32:50,504 --> 03:32:51,271 ANONYMIZATION OF DATA. 5261 03:32:51,271 --> 03:32:53,474 MANY OF THESE AT THIS POINT 5262 03:32:53,474 --> 03:32:55,642 DON'T REALLY EXIST FOR A.I. AND 5263 03:32:55,642 --> 03:32:57,511 M.L. APPLICATIONS BUT THEY ARE 5264 03:32:57,511 --> 03:32:59,279 CRITICAL IF WE WANT TO APPLY 5265 03:32:59,279 --> 03:33:03,350 THESE AT SCALE PARTICULARLY TO 5266 03:33:03,350 --> 03:33:09,356 CLINICAL DATA. 5267 03:33:09,356 --> 03:33:10,991 SO, AREA OF OPPORTUNITIES 5268 03:33:10,991 --> 03:33:12,960 RELATED TO CONVERTING DATA TO 5269 03:33:12,960 --> 03:33:13,627 APPLICATIONS. 5270 03:33:13,627 --> 03:33:15,362 I WON'T GO INTO DETAIL. 5271 03:33:15,362 --> 03:33:18,432 THERE'S MORE ON EACH OF THESE IN 5272 03:33:18,432 --> 03:33:20,300 THE REPORT, BUT QUICKLY POINT 5273 03:33:20,300 --> 03:33:24,905 OUT THAT THESE ARE RELATED SO 5274 03:33:24,905 --> 03:33:30,144 THREE AREAS RELATED TO IMAGING, 5275 03:33:30,144 --> 03:33:31,812 DATA SCIENCE WILL BE 5276 03:33:31,812 --> 03:33:33,981 INCREASINGLY IMPORTANT FOR 5277 03:33:33,981 --> 03:33:35,616 DIAGNOSTIC IMAGING, SUPPORTING 5278 03:33:35,616 --> 03:33:37,417 CLINICIANS IN DIAGNOSIS, A.I. 5279 03:33:37,417 --> 03:33:39,920 AND OTHER DATA SCIENCE-ENABLED 5280 03:33:39,920 --> 03:33:42,656 APPROACHES CAN GO THROUGH 5281 03:33:42,656 --> 03:33:44,825 IMAGING VERY QUICKLY, AND DO SO 5282 03:33:44,825 --> 03:33:47,794 WITH INCREASING ACCURACY. 5283 03:33:47,794 --> 03:33:51,298 IN SOME CASES BETTER THAN HUMAN 5284 03:33:51,298 --> 03:33:55,769 CURATOR, SO MAJOR OPPORTUNITIES 5285 03:33:55,769 --> 03:33:56,203 HERE. 5286 03:33:56,203 --> 03:33:59,406 GOOD AT FURTHER ENHANCING 5287 03:33:59,406 --> 03:34:01,241 CURRENT IMAGING DATA TO 5288 03:34:01,241 --> 03:34:02,009 FACILITATE DIAGNOSIS. 5289 03:34:02,009 --> 03:34:04,411 AND THEY CAN BE USED FOR 3D 5290 03:34:04,411 --> 03:34:06,914 IMAGING, ONE APPLICATION OF 5291 03:34:06,914 --> 03:34:09,650 WHICH IS PRECISION MEDICINE TO 5292 03:34:09,650 --> 03:34:11,218 LOOK AT DATA FROM A GIVEN 5293 03:34:11,218 --> 03:34:13,053 PATIENT TO HELP WITH THAT. 5294 03:34:13,053 --> 03:34:14,922 I TALKED ABOUT NATURAL LANGUAGE 5295 03:34:14,922 --> 03:34:15,556 PROCESSING. 5296 03:34:15,556 --> 03:34:18,959 THAT WAS, FOR EXAMPLE, ONE AREA 5297 03:34:18,959 --> 03:34:21,495 WHERE DATA SCIENCE APPROACHES 5298 03:34:21,495 --> 03:34:24,631 CAN HELP WITH CLINICAL RECORDS, 5299 03:34:24,631 --> 03:34:27,301 ANALYTICS, SO FURTHER ENHANCING 5300 03:34:27,301 --> 03:34:31,171 AND INTEGRATING DATA FOR THE 5301 03:34:31,171 --> 03:34:33,407 PATIENT, SUPPORTING DIAGNOSIS, 5302 03:34:33,407 --> 03:34:35,709 FOR EXAMPLE, OF -- BY 5303 03:34:35,709 --> 03:34:37,110 INTEGRATING PATHOLOGY WITH OTHER 5304 03:34:37,110 --> 03:34:39,413 CLINICAL DATA. 5305 03:34:39,413 --> 03:34:40,781 AND DEVELOPING STRATEGIES FOR 5306 03:34:40,781 --> 03:34:42,382 PERSONALIZED THERAPEUTICS FOR A 5307 03:34:42,382 --> 03:34:44,785 GIVEN PATIENT. 5308 03:34:44,785 --> 03:34:47,955 THIS INCLUDES MODELING OF 5309 03:34:47,955 --> 03:34:49,690 DIFFERENT OPTIONS, DIFFERENT 5310 03:34:49,690 --> 03:34:51,425 THERAPEUTIC OPTIONS, PREDICTING 5311 03:34:51,425 --> 03:34:55,095 WHAT THE OUTCOME WOULD BE, AND 5312 03:34:55,095 --> 03:34:57,598 SUPPORTING THE SELECTION OF 5313 03:34:57,598 --> 03:35:01,201 THERAPEUTIC OPTIONS. 5314 03:35:01,201 --> 03:35:05,806 I TALKED ABOUT GENERATEIVE 5315 03:35:05,806 --> 03:35:08,542 TECHNOLOGIES TO DEVELOP 5316 03:35:08,542 --> 03:35:09,409 IMPLANTS, DEVICES, SCAFFOLDS, SO 5317 03:35:09,409 --> 03:35:09,943 ON. 5318 03:35:09,943 --> 03:35:11,912 THE LAST ONE IS OUTSIDE THE 5319 03:35:11,912 --> 03:35:14,548 OTHER ONES BUT ALSO INCREASINGLY 5320 03:35:14,548 --> 03:35:15,115 IMPORTANT. 5321 03:35:15,115 --> 03:35:17,184 I THINK MICROBIOME WAS ALSO 5322 03:35:17,184 --> 03:35:21,788 MENTIONED TODAY. 5323 03:35:21,788 --> 03:35:22,556 MICROBIOME INFORMATICS, 5324 03:35:22,556 --> 03:35:25,092 INCREASINGLY APPRECIATING OUT IT 5325 03:35:25,092 --> 03:35:29,630 IMPACTS ON OUR HEALTH, AND 5326 03:35:29,630 --> 03:35:30,163 MICROBIOME RESEARCH, 5327 03:35:30,163 --> 03:35:31,231 METAGENOMICS, OF COURSE ANOTHER 5328 03:35:31,231 --> 03:35:32,766 AREA WHERE WE EXPECT TO SEE 5329 03:35:32,766 --> 03:35:37,671 MAJOR PROGRESS RELATED TO DATA 5330 03:35:37,671 --> 03:35:38,138 SCIENCE. 5331 03:35:38,138 --> 03:35:41,308 THE LAST OF THE OPPORTUNITY 5332 03:35:41,308 --> 03:35:42,709 AREAS RELATES TO DIVERSITY OF 5333 03:35:42,709 --> 03:35:44,278 DOC DATA. 5334 03:35:44,278 --> 03:35:46,680 I TALKED ABOUT HOW DOC DATA IS 5335 03:35:46,680 --> 03:35:49,616 VERY DIVERSE BUT WE BELIEVE THAT 5336 03:35:49,616 --> 03:35:52,452 THIS DIFFERENCE NOT JUST 5337 03:35:52,452 --> 03:35:53,353 CHALLENGES BUT ALSO 5338 03:35:53,353 --> 03:35:53,920 OPPORTUNITIES. 5339 03:35:53,920 --> 03:35:57,324 I TALKED ABOUT THE COMPLEXITY OF 5340 03:35:57,324 --> 03:36:00,227 DOC DATA, AND NEED TO INTEGRATE. 5341 03:36:00,227 --> 03:36:02,963 BUT WE BELIEVE THAT IF THIS IS 5342 03:36:02,963 --> 03:36:05,165 DONE RIGHT, FROM THIS COMPLEX 5343 03:36:05,165 --> 03:36:08,235 THIS THERE ARISE MAJOR 5344 03:36:08,235 --> 03:36:10,737 OPPORTUNITIES TO GAIN NEW 5345 03:36:10,737 --> 03:36:13,040 INSIGHTS FROM THESE INNOVATIVE 5346 03:36:13,040 --> 03:36:13,940 INTEGRATION APPROACHES, LOOKING 5347 03:36:13,940 --> 03:36:15,776 AT DATA FROM DIFFERENT ANGLES, 5348 03:36:15,776 --> 03:36:19,212 AND AT A SCALE THAT WAS 5349 03:36:19,212 --> 03:36:20,947 PREVIOUSLY NOT POSSIBLE TO 5350 03:36:20,947 --> 03:36:23,116 INFORM, FOR EXAMPLE, TO INFORM 5351 03:36:23,116 --> 03:36:27,754 HOW WE MIGHT ADDRESS ORAL HEALTH 5352 03:36:27,754 --> 03:36:28,155 DISPARITY. 5353 03:36:28,155 --> 03:36:31,224 THE SECOND IS DATA FRAGMENTATION 5354 03:36:31,224 --> 03:36:33,427 ACROSS SYSTEMS AND REPOSITORIES, 5355 03:36:33,427 --> 03:36:36,263 CURRENTLY A CHALLENGE BUT WE 5356 03:36:36,263 --> 03:36:38,131 BELIEVE THAT IF THIS IS DONE 5357 03:36:38,131 --> 03:36:41,702 RIGHT THIS IMPROVED DATA 5358 03:36:41,702 --> 03:36:43,270 MANAGEMENT WILL PROVIDE MAJOR 5359 03:36:43,270 --> 03:36:45,605 STEP FORWARD IN TERMS OF 5360 03:36:45,605 --> 03:36:47,074 ACCESSIBILITY, SO THE "A" IN 5361 03:36:47,074 --> 03:36:48,075 FAIR, RIGHT? 5362 03:36:48,075 --> 03:36:50,344 MAKING EASY FOR PEOPLE TO FIND 5363 03:36:50,344 --> 03:36:53,714 ACCESS TO DATA AND THEN USE IT 5364 03:36:53,714 --> 03:36:55,615 FOR ANALYSIS. 5365 03:36:55,615 --> 03:36:57,351 CURRENT LACK OF STANDARDS FOR 5366 03:36:57,351 --> 03:37:00,787 DATA AND METADATA IF WE ADDRESS 5367 03:37:00,787 --> 03:37:03,523 IT RIGHT WILL FACILITATE 5368 03:37:03,523 --> 03:37:04,257 CROSS-LINKING BETWEEN DATASETS, 5369 03:37:04,257 --> 03:37:06,360 WILL ENABLE THINGS SUCH AS 5370 03:37:06,360 --> 03:37:08,228 PREDICTIVE MODELING, ALL SORTS 5371 03:37:08,228 --> 03:37:09,096 OF STUDIES. 5372 03:37:09,096 --> 03:37:11,064 BUT IT IS REALLY KEY FOR BEING 5373 03:37:11,064 --> 03:37:15,068 ABLE TO BRING DIFFERENT TYPES OF 5374 03:37:15,068 --> 03:37:18,372 DATA TOGETHER. 5375 03:37:18,372 --> 03:37:24,077 THERE'S LIMITATIONS OF 5376 03:37:24,077 --> 03:37:25,145 SPECIALISTS AND GENERALIST 5377 03:37:25,145 --> 03:37:25,846 REPOSITORIES, IF INTEGRATED CAN 5378 03:37:25,846 --> 03:37:28,482 BE VALUABLE FOR INFORMING PUBLIC 5379 03:37:28,482 --> 03:37:30,317 HEALTH AND POLICY. 5380 03:37:30,317 --> 03:37:33,820 AND THEN THE LAST ONE IS I 5381 03:37:33,820 --> 03:37:35,589 TALKED ABOUT THESE BIASES IN 5382 03:37:35,589 --> 03:37:38,658 AVAILABLE DOC DATA, WHEN IT 5383 03:37:38,658 --> 03:37:41,161 COMES TO UNDERREPRESENTED 5384 03:37:41,161 --> 03:37:41,461 POPULATIONS. 5385 03:37:41,461 --> 03:37:42,929 AND THE POTENTIAL RISKS 5386 03:37:42,929 --> 03:37:43,897 ASSOCIATED WITH THIS. 5387 03:37:43,897 --> 03:37:45,599 SOMETHING I WANT TO POINT OUT AT 5388 03:37:45,599 --> 03:37:50,070 THIS POINT A LOT OF THIS IS THAT 5389 03:37:50,070 --> 03:37:55,075 ANECDOTAL FINDINGS, HARD TO 5390 03:37:55,075 --> 03:37:56,843 QUANTIFY SKEWS AND BIASES, USING 5391 03:37:56,843 --> 03:37:59,246 A.I. IN ETHICAL WAYS WILL HELP 5392 03:37:59,246 --> 03:38:01,748 UNDERSTAND IN MORE DETAIL HOW 5393 03:38:01,748 --> 03:38:03,417 EXACTLY EXISTING DATASETS ARE 5394 03:38:03,417 --> 03:38:04,918 SKEWED AND POSSIBLY CORRECT FOR 5395 03:38:04,918 --> 03:38:07,888 THAT OR GUIDE HOW WE CAN COLLECT 5396 03:38:07,888 --> 03:38:16,196 DATA IN THE FUTURE IN SMARTER 5397 03:38:16,196 --> 03:38:16,396 WAYS. 5398 03:38:16,396 --> 03:38:19,065 I COME TO THE LAST PART OF THE 5399 03:38:19,065 --> 03:38:21,034 PRESENTATION, THE ACTUAL 5400 03:38:21,034 --> 03:38:22,769 RECOMMENDATIONS THE WORKING 5401 03:38:22,769 --> 03:38:24,771 GROUP HAS FOR NIDCR IN THINKING 5402 03:38:24,771 --> 03:38:26,706 ABOUT A DATA SCIENCE STRATEGY. 5403 03:38:26,706 --> 03:38:29,342 SO, WHAT WE TRIED TO DO IS TOOK 5404 03:38:29,342 --> 03:38:32,212 ALL THE KEY FINDINGS, 5405 03:38:32,212 --> 03:38:33,013 OBSERVATIONS, THE OPPORTUNITIES, 5406 03:38:33,013 --> 03:38:35,682 AND THOUGHT ABOUT HOW WE CAN 5407 03:38:35,682 --> 03:38:37,350 TURN THEM INTO MORE SPECIFIC 5408 03:38:37,350 --> 03:38:38,418 THINGS THAT WE THINK WOULD BE 5409 03:38:38,418 --> 03:38:41,888 IMPORTANT TO DO. 5410 03:38:41,888 --> 03:38:43,056 NOW, TO PRESENT THIS, WE THOUGHT 5411 03:38:43,056 --> 03:38:45,525 IT WOULD BE REALLY IMPORTANT TO 5412 03:38:45,525 --> 03:38:49,830 ALIGN THIS WITH THE BROADER NIH 5413 03:38:49,830 --> 03:38:52,132 DATA SCIENCE STRATEGY. 5414 03:38:52,132 --> 03:38:55,168 SO, NIH CURRENTLY OPERATES UNDER 5415 03:38:55,168 --> 03:38:57,904 THIS NIH STRATEGIC PLAN FOR DATA 5416 03:38:57,904 --> 03:38:59,873 SCIENCE, WHICH CAME OUT OF 5417 03:38:59,873 --> 03:39:01,441 OFFICE OF DATA SCIENCE STRATEGY. 5418 03:39:01,441 --> 03:39:04,945 THE CURRENT VERSION OF THIS PLAN 5419 03:39:04,945 --> 03:39:08,014 WAS IN 2018, CURRENTLY WORKING 5420 03:39:08,014 --> 03:39:09,850 HARD ON A REVISION OF THIS PLAN, 5421 03:39:09,850 --> 03:39:11,952 AND SO A NEW VERSION OF THIS 5422 03:39:11,952 --> 03:39:13,587 PLAN IS EXPECTED TO COME OUT 5423 03:39:13,587 --> 03:39:15,222 LATER THIS YEAR. 5424 03:39:15,222 --> 03:39:18,492 IT IS, HOWEVER, NOT FINAL YET SO 5425 03:39:18,492 --> 03:39:19,759 WE USED THE GENERAL FRAMEWORK 5426 03:39:19,759 --> 03:39:22,762 AND STRUCTURE OF THE 5427 03:39:22,762 --> 03:39:25,298 RECOMMENDATIONS IN THIS NIH -- 5428 03:39:25,298 --> 03:39:28,468 IN THE 2018 NIH-WIDE PLAN TO 5429 03:39:28,468 --> 03:39:30,237 FRAME OUR RECOMMENDATIONS, WHICH 5430 03:39:30,237 --> 03:39:35,909 MAKES IT EASY TO ALIGN WITH THE 5431 03:39:35,909 --> 03:39:37,244 BROADER NIH STRATEGY. 5432 03:39:37,244 --> 03:39:39,980 SO, IN ALL FIVE AREAS THAT ARE 5433 03:39:39,980 --> 03:39:42,849 CALLED OUT IN THE NIH PLANS WE 5434 03:39:42,849 --> 03:39:44,017 THOUGHT ABOUT HOW DOES THIS 5435 03:39:44,017 --> 03:39:46,353 RELATE TO DOC, THOUGHT ABOUT KEY 5436 03:39:46,353 --> 03:39:48,755 FINDINGS THAT WE HAVE IN THE DOC 5437 03:39:48,755 --> 03:39:52,259 SPACE, AND WHAT WERE 5438 03:39:52,259 --> 03:39:52,926 RECOMMENDATIONS SPECIFICALLY FOR 5439 03:39:52,926 --> 03:39:53,994 DOC RESEARCH THAT SHOULD RESULT 5440 03:39:53,994 --> 03:39:54,861 FROM THAT. 5441 03:39:54,861 --> 03:39:59,032 THE FIRST SET OF RECOMMENDATIONS 5442 03:39:59,032 --> 03:40:03,837 RELATE TO OUR FINDINGS THAT DOC 5443 03:40:03,837 --> 03:40:05,672 DATA IS COMPLEX AND 5444 03:40:05,672 --> 03:40:07,340 HETEROGENOUS, THERE'S A LACK OF 5445 03:40:07,340 --> 03:40:08,775 CONNECTIVITY AND BOUNDARIES AND 5446 03:40:08,775 --> 03:40:11,077 LACK OF DEDICATED RESOURCE FOR 5447 03:40:11,077 --> 03:40:13,446 SUPPORTING DIVERSE DATA TYPES. 5448 03:40:13,446 --> 03:40:17,651 AND SO FIRST SET OF 5449 03:40:17,651 --> 03:40:19,152 RECOMMENDATIONS IS EXPLICITLY 5450 03:40:19,152 --> 03:40:21,254 DATA INFRASTRUCTURE. 5451 03:40:21,254 --> 03:40:23,890 WE RECOMMEND THAT NIDCR PUT 5452 03:40:23,890 --> 03:40:27,160 EFFORT INTO ESTABLISHING ROBUST 5453 03:40:27,160 --> 03:40:29,029 DATA INFRASTRUCTURE, WITH 5454 03:40:29,029 --> 03:40:30,263 PARTICULAR NEEDS AND PROPERTIES 5455 03:40:30,263 --> 03:40:32,999 OF DOC RESEARCH IN MIND, BUT 5456 03:40:32,999 --> 03:40:35,368 ALSO WITH INTEGRATION WITH THE 5457 03:40:35,368 --> 03:40:40,073 LARGER NIH DATA SYSTEM IN MIND. 5458 03:40:40,073 --> 03:40:42,609 WHAT THIS INVOLVES IS SUPPORT 5459 03:40:42,609 --> 03:40:45,078 FOR OPTIMIZED DATA AND DATA 5460 03:40:45,078 --> 03:40:49,182 STORAGE AND SECURITY FOR DOC 5461 03:40:49,182 --> 03:40:49,449 RESEARCH. 5462 03:40:49,449 --> 03:40:52,552 IMPROVING THE CONNECTIVITY OF 5463 03:40:52,552 --> 03:40:54,654 EXISTING AND FUTURE DOC SPECIFIC 5464 03:40:54,654 --> 03:40:57,290 WITH GENERAL NIH DATA SYSTEMS 5465 03:40:57,290 --> 03:40:59,593 AND POSSIBLY EVEN BEYOND THE 5466 03:40:59,593 --> 03:41:03,530 NIH-FUNDED SPACE WITH MORE 5467 03:41:03,530 --> 03:41:05,065 GENERAL SYSTEMS, MAKING SURE WE 5468 03:41:05,065 --> 03:41:14,274 USE A.I. AND M.L. IN ETHICAL 5469 03:41:14,274 --> 03:41:15,609 WAYS AND SUPPORT ETHICAL USE OF 5470 03:41:15,609 --> 03:41:17,010 A.I. AND M.L. 5471 03:41:17,010 --> 03:41:18,311 SECOND SET OF RECOMMENDATIONS 5472 03:41:18,311 --> 03:41:22,048 RELATES TO THE FIRST ONE, BUT IT 5473 03:41:22,048 --> 03:41:23,683 IS MORE SPECIFICALLY FOCUSED ON 5474 03:41:23,683 --> 03:41:24,317 DATA ECOSYSTEM. 5475 03:41:24,317 --> 03:41:26,620 SO ON THE TYPE OF DATA SYSTEMS 5476 03:41:26,620 --> 03:41:29,823 THAT LIVE WITHIN THIS 5477 03:41:29,823 --> 03:41:30,357 INFRASTRUCTURE. 5478 03:41:30,357 --> 03:41:32,659 THIS WAS KEY FINDINGS IN TERMS 5479 03:41:32,659 --> 03:41:35,729 OF CHALLENGES IN INTEGRATING 5480 03:41:35,729 --> 03:41:38,365 ACROSS DIVERSE DATA TYPES. 5481 03:41:38,365 --> 03:41:39,899 THE CURRENT DIVERSITY AND 5482 03:41:39,899 --> 03:41:42,636 FRAGMENTATION OF DATA ACROSS 5483 03:41:42,636 --> 03:41:46,239 REPOSITORIES, AND THE NEED FOR 5484 03:41:46,239 --> 03:41:48,875 MORE COMPREHENSIVE APPROACH THAT 5485 03:41:48,875 --> 03:41:51,478 ALSO INTEGRATES WITH NIH'S 5486 03:41:51,478 --> 03:41:55,448 VISION FOR THE BROADER NIH-WIDE 5487 03:41:55,448 --> 03:41:57,083 DATA INFRASTRUCTURE. 5488 03:41:57,083 --> 03:41:59,619 SO, WITHIN THAT INFRASTRUCTURE, 5489 03:41:59,619 --> 03:42:02,222 WE RECOMMEND THAT EFFORT IS PUT 5490 03:42:02,222 --> 03:42:04,758 INTO MODERNIZING THE DATA 5491 03:42:04,758 --> 03:42:08,028 ECOSYSTEMS SPECIFIC TO DOC 5492 03:42:08,028 --> 03:42:08,294 RESEARCH. 5493 03:42:08,294 --> 03:42:11,965 THIS WILL INCLUDE THE CREATION 5494 03:42:11,965 --> 03:42:16,903 OF DATA REPOSITORIES FOR DOC 5495 03:42:16,903 --> 03:42:18,638 RESEARCH, NEW REPOSITORIES OR 5496 03:42:18,638 --> 03:42:20,940 EXPANSION OF EXISTING 5497 03:42:20,940 --> 03:42:24,010 REPOSITORIES THAT REFLECT THE 5498 03:42:24,010 --> 03:42:26,646 GENERAL NIH OBJECTIVES FOR DATA 5499 03:42:26,646 --> 03:42:27,113 REPOSITORIES. 5500 03:42:27,113 --> 03:42:29,916 THESE INCLUDE CRITERIA SUCH AS 5501 03:42:29,916 --> 03:42:33,119 BEING COST EFFECTIVE, THEN ALSO 5502 03:42:33,119 --> 03:42:37,057 COMPLIANCE WITH FAIR CRITERIA, 5503 03:42:37,057 --> 03:42:39,225 SUSTAINABLE, SECURE, ACCESSIBLE. 5504 03:42:39,225 --> 03:42:42,062 AND SUPPORTING THE STORAGE AND 5505 03:42:42,062 --> 03:42:44,698 SHARING OF INDIVIDUAL DATASETS 5506 03:42:44,698 --> 03:42:50,136 AND SOFTWARE TOOLS. 5507 03:42:50,136 --> 03:42:53,339 FINALLY, ALSO RECOMMEND THAT 5508 03:42:53,339 --> 03:42:56,309 NIDCR LEVERAGE ONGOING 5509 03:42:56,309 --> 03:42:57,410 INITIATIVES TO BETTER INTEGRATE 5510 03:42:57,410 --> 03:43:00,146 THE CLINICAL AND OBSERVATIONAL 5511 03:43:00,146 --> 03:43:02,982 DATA INTO DOC DATA SCIENCE AND 5512 03:43:02,982 --> 03:43:05,518 THIS CAN GO BEYOND JUST 5513 03:43:05,518 --> 03:43:06,352 BIOMEDICAL DATA. 5514 03:43:06,352 --> 03:43:11,991 THE THIRD SET OF RECOMMENDATIONS 5515 03:43:11,991 --> 03:43:14,994 RELATES, THESE WOULD BE ON TOP 5516 03:43:14,994 --> 03:43:16,429 OF THE INFRASTRUCTURE IN THE 5517 03:43:16,429 --> 03:43:18,865 SYSTEM, HOW CAN WE MAKE SURE 5518 03:43:18,865 --> 03:43:22,569 THAT THE RIGHT TOOLS ARE BEING 5519 03:43:22,569 --> 03:43:25,839 DEVELOPED AND DEPLOYED FOR DOC 5520 03:43:25,839 --> 03:43:27,807 RESEARCH, SO WE CLEARLY NEED 5521 03:43:27,807 --> 03:43:29,809 BETTER TOOLS TO INTEGRATE AND 5522 03:43:29,809 --> 03:43:32,645 EXTRACT VALUE ON DIVERSE DATA 5523 03:43:32,645 --> 03:43:34,380 TYPES, MANAGING DIVERSITY OF 5524 03:43:34,380 --> 03:43:38,251 DATA, AND SHOWING UTILITY OF 5525 03:43:38,251 --> 03:43:40,520 DATA, AND OPERATIONAL 5526 03:43:40,520 --> 03:43:41,121 EFFICIENCY. 5527 03:43:41,121 --> 03:43:44,591 THIS MEANS DEVELOPMENT OF DATA 5528 03:43:44,591 --> 03:43:45,558 MANAGEMENT TOOLS, VISUALIZATION 5529 03:43:45,558 --> 03:43:49,963 TOOLS FOR DOC RESEARCH. 5530 03:43:49,963 --> 03:43:53,433 SO WE'RE RECOMMENDING SUPPORT OF 5531 03:43:53,433 --> 03:43:57,137 GENERALIZABLE TOOLS AND WORK 5532 03:43:57,137 --> 03:44:01,975 FLOWS FOR DOC DATA, BROADEN 5533 03:44:01,975 --> 03:44:04,277 UTILITY AND USABILITY OF 5534 03:44:04,277 --> 03:44:06,112 SPECIALIZED TOOLS THAT ALREADY 5535 03:44:06,112 --> 03:44:08,982 EXIST, MAKING THEM MORE WIDELY 5536 03:44:08,982 --> 03:44:09,949 ACCESSIBLE. 5537 03:44:09,949 --> 03:44:13,353 AND DEVELOPMENT OF TOOLS TO 5538 03:44:13,353 --> 03:44:16,422 IMPROVE HOW PEOPLE CAN FIND 5539 03:44:16,422 --> 03:44:17,423 EXISTING RESOURCES, EXISTING 5540 03:44:17,423 --> 03:44:21,161 DATA, AND HOW THEY USE THE 5541 03:44:21,161 --> 03:44:22,128 EXISTING TOOLS. 5542 03:44:22,128 --> 03:44:26,132 THE FOURTH SET OF 5543 03:44:26,132 --> 03:44:28,034 RECOMMENDATIONS RELATES TO 5544 03:44:28,034 --> 03:44:28,301 WORKFORCE. 5545 03:44:28,301 --> 03:44:31,771 SO, WE CLEARLY NEED A MORE 5546 03:44:31,771 --> 03:44:33,973 KNOWLEDGEABLE WORKFORCE THAT IS 5547 03:44:33,973 --> 03:44:38,978 WELL EDUCATED IN BEST PRACTICES, 5548 03:44:38,978 --> 03:44:40,079 DATA MANAGEMENT, EDUCATION 5549 03:44:40,079 --> 03:44:43,783 OPPORTUNITIES OF DATA SCIENCE. 5550 03:44:43,783 --> 03:44:46,419 AND CURRENTLY THERE'S A 5551 03:44:46,419 --> 03:44:49,189 PARTICULAR SHORTAGE IN PEOPLE 5552 03:44:49,189 --> 03:44:51,558 WITH ADEQUATE TRAINING IN 5553 03:44:51,558 --> 03:44:54,194 POPULATION HEALTH RESEARCH 5554 03:44:54,194 --> 03:44:55,728 SPECIFICALLY TO DOC DATA, THAT 5555 03:44:55,728 --> 03:44:58,264 WAS ANOTHER MAJOR OPPORTUNITY. 5556 03:44:58,264 --> 03:45:01,968 SO IN TERMS OF DEVELOPING SUCH A 5557 03:45:01,968 --> 03:45:03,837 WORKFORCE, THERE ARE THREE 5558 03:45:03,837 --> 03:45:04,204 RECOMMENDATIONS. 5559 03:45:04,204 --> 03:45:07,907 ONE IS TO FURTHER STRENGTHEN THE 5560 03:45:07,907 --> 03:45:10,076 NIDCR INTERNAL DATA SCIENCE 5561 03:45:10,076 --> 03:45:10,343 WORKFORCE. 5562 03:45:10,343 --> 03:45:14,147 WE HEARD A LITTLE BIT OF THAT 5563 03:45:14,147 --> 03:45:16,216 EARLIER TODAY. 5564 03:45:16,216 --> 03:45:18,751 SO INCREASING EFFORTS TO PROVIDE 5565 03:45:18,751 --> 03:45:22,689 EDUCATION AND BACKGROUND OF 5566 03:45:22,689 --> 03:45:25,959 EXISTING NIDCR PROGRAM STAFF BUT 5567 03:45:25,959 --> 03:45:27,460 PERHAPS ALSO HAVING DEDICATED 5568 03:45:27,460 --> 03:45:31,531 NEW POSITIONS THAT CAN SUPPORT 5569 03:45:31,531 --> 03:45:32,565 THIS. 5570 03:45:32,565 --> 03:45:35,568 DEVELOPING A STRONG AND DIVERSE 5571 03:45:35,568 --> 03:45:39,873 FUTURE WORKFORCE FOR DOC DATA 5572 03:45:39,873 --> 03:45:43,142 SCIENCE, WITH A FOCUS ON 5573 03:45:43,142 --> 03:45:45,545 POPULATION HEALTH RESEARCH. 5574 03:45:45,545 --> 03:45:49,048 AND ENGAGING A BROADER 5575 03:45:49,048 --> 03:45:50,183 COMMUNITY. 5576 03:45:50,183 --> 03:45:51,484 AND ESPECIALLY WITH THIS LAST 5577 03:45:51,484 --> 03:45:52,585 COMMENT, ONE SPECIFIC 5578 03:45:52,585 --> 03:45:54,654 RECOMMENDATION THAT THE WORKING 5579 03:45:54,654 --> 03:45:57,257 GROUP HAS IS THAT NIDCR SHOULD 5580 03:45:57,257 --> 03:45:59,592 CONSIDER THE CREATION OF AN 5581 03:45:59,592 --> 03:46:00,860 NIDCR DATA HUB, THAT'S WHAT THEY 5582 03:46:00,860 --> 03:46:03,062 CALLED IT. 5583 03:46:03,062 --> 03:46:05,798 THIS WAS DRIVEN BY THE THE 5584 03:46:05,798 --> 03:46:10,069 OBSERVATION OR IN PART DRIVEN BY 5585 03:46:10,069 --> 03:46:11,838 THE OBSERVATION THAT ONE OF THE 5586 03:46:11,838 --> 03:46:13,473 MAJOR DATA SCIENCE EFFORTS 5587 03:46:13,473 --> 03:46:21,447 SUPPORTED BY NIDCR HAS A HELP 5588 03:46:21,447 --> 03:46:22,749 DESK FOR FACEBASED USERS, 5589 03:46:22,749 --> 03:46:23,950 SUCCESSFUL IN GUIDING THEM. 5590 03:46:23,950 --> 03:46:25,618 WHAT'S IMPACTFUL IS IF THERE WAS 5591 03:46:25,618 --> 03:46:28,021 A CENTRAL PLACE, THIS COULD BE 5592 03:46:28,021 --> 03:46:31,858 LOCATED WITHIN NIDCR, IT COULD 5593 03:46:31,858 --> 03:46:35,128 BE EXTERNAL EFFORT THAT IS 5594 03:46:35,128 --> 03:46:36,996 SUPPORTED BY NIDCR BUT A SINGLE 5595 03:46:36,996 --> 03:46:38,298 GO-TO SPACE THAT ANYONE WHO 5596 03:46:38,298 --> 03:46:40,500 PRODUCES OR WANTS TO USE DOC 5597 03:46:40,500 --> 03:46:43,102 DATA CAN GO TO MAKE SURE THAT 5598 03:46:43,102 --> 03:46:45,338 WHAT THEY ARE DOING IS 5599 03:46:45,338 --> 03:46:46,339 CONSISTENT WITH BEST PRACTICES, 5600 03:46:46,339 --> 03:46:48,308 UNDERSTANDING WHERE TO PUT DATA, 5601 03:46:48,308 --> 03:46:51,911 WHERE TO FIND DATA, HOW TO 5602 03:46:51,911 --> 03:46:53,980 PROVIDE DATA IN WAYS THAT IS 5603 03:46:53,980 --> 03:46:58,685 MOST USEFUL TO OTHER 5604 03:46:58,685 --> 03:46:59,018 RESEARCHERS. 5605 03:46:59,018 --> 03:47:02,355 THE LAST SET OF RECOMMENDATIONS 5606 03:47:02,355 --> 03:47:03,656 RELATES TO DATA STEWARDSHIP. 5607 03:47:03,656 --> 03:47:06,960 SO WE HEARD FROM THE COMMUNITY 5608 03:47:06,960 --> 03:47:11,998 ABOUT CHALLENGES IN MAKING SURE 5609 03:47:11,998 --> 03:47:16,703 THAT DATA IS AVAILABLE, IN A 5610 03:47:16,703 --> 03:47:17,236 SUSTAINABLE WAY. 5611 03:47:17,236 --> 03:47:18,571 CONCERNS ABOUT MANY OF THE 5612 03:47:18,571 --> 03:47:21,207 CURRENT DATA SCIENCE EFFORTS 5613 03:47:21,207 --> 03:47:24,277 BEING SUPPORTED CURRENTLY UNDER 5614 03:47:24,277 --> 03:47:26,579 RESEARCH GRANTS WITH LIMITED 5615 03:47:26,579 --> 03:47:30,516 DURATION, AND HOW THIS RELATES 5616 03:47:30,516 --> 03:47:34,120 TO FAIR PRINCIPLES AND SO WE 5617 03:47:34,120 --> 03:47:37,090 BELIEVE NIDCR COULD TAKE A MORE 5618 03:47:37,090 --> 03:47:40,460 ACTIVE OR MORE PRO-ACTIVE 5619 03:47:40,460 --> 03:47:42,528 APPROACH IN REALLY ENSURING AND, 5620 03:47:42,528 --> 03:47:46,165 YOU KNOW, TAKING RESPONSIBILITY 5621 03:47:46,165 --> 03:47:47,700 FOR DATA STEWARDSHIP AND 5622 03:47:47,700 --> 03:47:48,768 IMPLEMENTING SUSTAINABLE DATA 5623 03:47:48,768 --> 03:47:50,336 POLICIES IN DOC RESEARCH. 5624 03:47:50,336 --> 03:47:53,840 THIS WILL INCLUDE DEVELOPMENT OF 5625 03:47:53,840 --> 03:47:56,242 POLICIES FOR FAIR DOC DATA, SO 5626 03:47:56,242 --> 03:47:58,878 OF COURSE THERE ARE NIH-WIDE 5627 03:47:58,878 --> 03:48:01,047 EFFORTS WITH A NEW DATA 5628 03:48:01,047 --> 03:48:02,915 MANAGEMENT AND SHARING PLANS, 5629 03:48:02,915 --> 03:48:04,450 BUT THEN THINKING ABOUT THE 5630 03:48:04,450 --> 03:48:09,255 SPECIFIC ASPECT AS THEY RELATE 5631 03:48:09,255 --> 03:48:12,225 TO DOC DATA, AND SPECIFIC NEEDS 5632 03:48:12,225 --> 03:48:14,427 OF THE DOC RESEARCH COMMUNITY, 5633 03:48:14,427 --> 03:48:17,597 MAKING SURE THAT POLICIES ARE IN 5634 03:48:17,597 --> 03:48:18,364 PLACE. 5635 03:48:18,364 --> 03:48:20,199 AND MORE GENERALLY ENHANCING 5636 03:48:20,199 --> 03:48:21,401 STEWARDSHIP OF DOC DATA BY 5637 03:48:21,401 --> 03:48:24,604 MAKING SURE ALL OF THE DATA THAT 5638 03:48:24,604 --> 03:48:27,440 IS PRODUCED UNDER NIDCR FUNDING 5639 03:48:27,440 --> 03:48:30,176 IS REALLY SUBJECT TO STRONG 5640 03:48:30,176 --> 03:48:31,544 STEWARDSHIP TO MAKE SURE THAT IT 5641 03:48:31,544 --> 03:48:32,779 WILL BE AVAILABLE IN THE FUTURE 5642 03:48:32,779 --> 03:48:37,050 AND THAT IT IS AVAILABLE IN WAYS 5643 03:48:37,050 --> 03:48:39,886 THAT MAXIMIZE THE UTILITY FOR 5644 03:48:39,886 --> 03:48:43,489 FUTURE STUDIES. 5645 03:48:43,489 --> 03:48:45,525 SO, WITH THIS, I JUST WANT TO 5646 03:48:45,525 --> 03:48:48,361 POINT OUT TO THE COUNCIL MEMBERS 5647 03:48:48,361 --> 03:48:49,662 AND LEADERSHIP AGAIN THAT THERE 5648 03:48:49,662 --> 03:48:52,598 IS THE FINAL REPORT THAT GOES 5649 03:48:52,598 --> 03:48:55,334 ALONG WITH THIS PRESENTATION. 5650 03:48:55,334 --> 03:48:57,203 IT'S AVAILABLE IN YOUR COUNCIL 5651 03:48:57,203 --> 03:48:58,304 DOCUMENTS, AND WE'RE LOOKING 5652 03:48:58,304 --> 03:49:00,173 FORWARD TO GETTING YOUR COMMENTS 5653 03:49:00,173 --> 03:49:03,142 ON THIS AND THEN DEPENDING WHAT 5654 03:49:03,142 --> 03:49:05,978 KIND OF COMMENTS WE GET WE MIGHT 5655 03:49:05,978 --> 03:49:08,281 MAKE ADDITIONAL CHANGES OR 5656 03:49:08,281 --> 03:49:09,148 ADDITIONS TO THIS REPORT. 5657 03:49:09,148 --> 03:49:11,551 I WANT TO TAKE THIS OPPORTUNITY 5658 03:49:11,551 --> 03:49:14,954 TO THANK MEMBERS OF THE WORKING 5659 03:49:14,954 --> 03:49:16,889 GROUP, NIDCR STAFF, WHO 5660 03:49:16,889 --> 03:49:19,092 CONTRIBUTED TO THE WORK OF THIS 5661 03:49:19,092 --> 03:49:20,126 WORKING GROUP. 5662 03:49:20,126 --> 03:49:22,328 IT WAS GREAT FUN OVER THE PAST 5663 03:49:22,328 --> 03:49:24,697 15 MONTHS TO DO THIS. 5664 03:49:24,697 --> 03:49:28,768 IT WAS WORK BUT ALSO REALLY 5665 03:49:28,768 --> 03:49:33,005 STIMULATING AND REWARDING 5666 03:49:33,005 --> 03:49:33,873 EXPERIENCE. 5667 03:49:33,873 --> 03:49:37,176 AND WITH THAT, I'M AT THE END. 5668 03:49:37,176 --> 03:49:38,945 WE'RE ALMOST AT TIME BUT I HOPE 5669 03:49:38,945 --> 03:49:40,780 I LEFT ENOUGH TIME FOR SOME 5670 03:49:40,780 --> 03:49:41,047 QUESTIONS. 5671 03:49:41,047 --> 03:49:42,982 THANK YOU. 5672 03:49:42,982 --> 03:49:44,951 >> THANK YOU, DR. VISEL. 5673 03:49:44,951 --> 03:49:48,387 ARE THERE ANY QUESTIONS? 5674 03:49:48,387 --> 03:49:51,057 WOULD SOMEONE LIKE TO -- 5675 03:49:51,057 --> 03:49:52,625 >> THERE ARE PEOPLE FROM THE 5676 03:49:52,625 --> 03:49:54,293 COMMITTEE LIKE CARL AND OTHERS 5677 03:49:54,293 --> 03:49:55,895 WHO COULD SPEAK AS WELL. 5678 03:49:55,895 --> 03:49:56,896 >> OH, YES. 5679 03:49:56,896 --> 03:49:59,732 I FORGOT TO ACKNOWLEDGE THAT. 5680 03:49:59,732 --> 03:50:02,268 YES, THERE ARE -- WHEN I SHOWED 5681 03:50:02,268 --> 03:50:05,972 THIS SLIDE THERE WERE SEVERAL 5682 03:50:05,972 --> 03:50:09,575 PEOPLE ON THE CALL TODAY, SO 5683 03:50:09,575 --> 03:50:11,577 THEY MAY CHIME IN WITH SPECIFIC 5684 03:50:11,577 --> 03:50:13,946 QUESTIONS OR IF THEY WANT TO 5685 03:50:13,946 --> 03:50:16,048 SPECIFICALLY COMMENT ON ANYTHING 5686 03:50:16,048 --> 03:50:17,783 THAT I JUST SAID, I WOULD INVITE 5687 03:50:17,783 --> 03:50:22,522 THEM TO DO SO. 5688 03:50:22,522 --> 03:50:24,323 >> BROUGHT THE WHOLE TEAM FOR 5689 03:50:24,323 --> 03:50:24,757 THE EXPERTISE. 5690 03:50:24,757 --> 03:50:25,324 >> WOW! 5691 03:50:25,324 --> 03:50:28,528 WHAT A RANGE OF EXPERTISE HE 5692 03:50:28,528 --> 03:50:37,270 BROUGHT TO PLAY HERE, THANK YOU. 5693 03:50:37,270 --> 03:50:38,871 MANY THEMES RESONATE WITH US. 5694 03:50:38,871 --> 03:50:40,439 WE'RE ON THE SAME WAVELENGTH. 5695 03:50:40,439 --> 03:50:42,175 I HAVE A FEW QUESTIONS. 5696 03:50:42,175 --> 03:50:46,112 AS WE EMBARK ON THE NEW 5697 03:50:46,112 --> 03:50:51,050 INITIATIVE, HOW DO WE COORDINATE 5698 03:50:51,050 --> 03:50:57,056 DATA ACROSS, SAY, CANCER 5699 03:50:57,056 --> 03:50:57,456 BIOMARKER CHARGE, 5700 03:50:57,456 --> 03:50:58,057 TEMPOROMANDIBULAR DYSFUNCTION 5701 03:50:58,057 --> 03:51:01,527 AND WHAT'S GOING ON IN DENTAL 5702 03:51:01,527 --> 03:51:02,862 SCHOOL, EACH WILL HAVE ITS OWN 5703 03:51:02,862 --> 03:51:04,497 DENTAL SYSTEM, WE HOPE THAT 5704 03:51:04,497 --> 03:51:08,100 HAPPENS, SHOULD THERE BE ONE 5705 03:51:08,100 --> 03:51:08,568 FEDERATED CENTER THAT 5706 03:51:08,568 --> 03:51:12,271 COORDINATES THAT OR -- I MEAN A 5707 03:51:12,271 --> 03:51:15,675 FEDERATED CENTER NOT OWNING 5708 03:51:15,675 --> 03:51:16,742 REPOSITORIES BUT SIMPLY BEING 5709 03:51:16,742 --> 03:51:19,512 THE HUB WHICH IS THE WAY I THINK 5710 03:51:19,512 --> 03:51:20,713 NIH IS THINKING THE NATIONAL 5711 03:51:20,713 --> 03:51:23,115 LIBRARY OF MEDICINE COULD EVOLVE 5712 03:51:23,115 --> 03:51:25,318 TO, BEING THE CENTRALIZED 5713 03:51:25,318 --> 03:51:26,752 REPOSITORY ALMOST IMPOSSIBLE TO 5714 03:51:26,752 --> 03:51:28,387 CONCEIVE OF FOR AN INSTITUTE OUR 5715 03:51:28,387 --> 03:51:28,955 SIZE. 5716 03:51:28,955 --> 03:51:33,092 HOW DOES ONE DEAL WITH 5717 03:51:33,092 --> 03:51:34,193 PREEXISTING DATASETS THAT WE'VE 5718 03:51:34,193 --> 03:51:37,797 INVESTED IN ALL THESE YEARS NOT 5719 03:51:37,797 --> 03:51:38,998 NECESSARILY CURATED IN THE 5720 03:51:38,998 --> 03:51:40,866 MANNER IN WHICH WE EXPECT THEM 5721 03:51:40,866 --> 03:51:42,602 TO BE TODAY? 5722 03:51:42,602 --> 03:51:45,671 WHAT DOES ONE DO, GO BACK AND 5723 03:51:45,671 --> 03:51:47,640 REVISIT THAT DATASET AND FILL IN 5724 03:51:47,640 --> 03:51:48,641 THE GAPS? 5725 03:51:48,641 --> 03:51:53,813 OR SIMPLY START FROM SCRATCH? 5726 03:51:53,813 --> 03:51:57,283 THOSE ARE MY TWO QUESTIONS, 5727 03:51:57,283 --> 03:51:58,284 CENTRALIZED VERSUS FEDERATED, 5728 03:51:58,284 --> 03:52:02,121 AND EXISTING VERSUS NEW 5729 03:52:02,121 --> 03:52:02,388 DATASETS. 5730 03:52:02,388 --> 03:52:06,659 >> I SEE CARL HAS A HAND UP. 5731 03:52:06,659 --> 03:52:07,193 >> AND JACQUES. 5732 03:52:07,193 --> 03:52:08,861 >> IF HE WANTS TO COMMENT ON 5733 03:52:08,861 --> 03:52:09,061 THAT. 5734 03:52:09,061 --> 03:52:10,329 >> HI. 5735 03:52:10,329 --> 03:52:12,632 THANK YOU. 5736 03:52:12,632 --> 03:52:15,901 I'M CARL TESTELMAN, ONE OF THE 5737 03:52:15,901 --> 03:52:17,436 CO-P.I.S OF FACEBASE, 5738 03:52:17,436 --> 03:52:20,506 PARTICIPATED IN THIS VERY 5739 03:52:20,506 --> 03:52:22,041 INTERESTING ACTIVITY. 5740 03:52:22,041 --> 03:52:24,210 SO, TO ADDRESS YOUR TWO 5741 03:52:24,210 --> 03:52:27,613 QUESTIONS, I WOULD SAY FIRST 5742 03:52:27,613 --> 03:52:29,682 WITH REGARD TO FEDERATED VERSUS 5743 03:52:29,682 --> 03:52:30,683 CENTRALIZES, ONE OF THE 5744 03:52:30,683 --> 03:52:32,652 CONCLUSIONS OF THE WORD IS 5745 03:52:32,652 --> 03:52:37,990 HAVING SOMETHING THAT'S FOCUSED 5746 03:52:37,990 --> 03:52:40,726 ON DOC RESEARCH WILL BE OF VALUE 5747 03:52:40,726 --> 03:52:42,828 TO NIDCR COMMUNITY, SO FINDING 5748 03:52:42,828 --> 03:52:45,998 APPROPRIATE BALANCE BETWEEN 5749 03:52:45,998 --> 03:52:47,633 COORDINATION SO NOT SQUANDERING 5750 03:52:47,633 --> 03:52:49,502 EFFORT BUT STILL MAINTAINING 5751 03:52:49,502 --> 03:52:52,238 DIFFERENTIATION OF THE RESOURCE 5752 03:52:52,238 --> 03:52:53,439 FOR DOC RESEARCH. 5753 03:52:53,439 --> 03:53:00,446 AND SO THAT COULD BE DONE IN A 5754 03:53:00,446 --> 03:53:03,049 MORE FORMAL OR INFORMAL WAY BUT 5755 03:53:03,049 --> 03:53:03,983 INTERCOORDINATION AT SOME LEVEL 5756 03:53:03,983 --> 03:53:05,351 WOULD BE DESIRABLE SO MAYBE 5757 03:53:05,351 --> 03:53:09,388 THERE'S A FORM THAT COULD TAKE 5758 03:53:09,388 --> 03:53:10,289 PLACE IN WHICH EVERYONE HAS A 5759 03:53:10,289 --> 03:53:13,225 SEAT AT THE TABLE AND UNIQUE 5760 03:53:13,225 --> 03:53:14,527 REQUIREMENTS OF THIS COMMUNITY 5761 03:53:14,527 --> 03:53:15,094 ADDRESSED. 5762 03:53:15,094 --> 03:53:16,162 WITH REGARDS TO EXISTING DATA, 5763 03:53:16,162 --> 03:53:18,030 YOU KNOW, I THINK YOU NEED TO 5764 03:53:18,030 --> 03:53:20,466 EVALUATE THE QUALITY OF THE DATA 5765 03:53:20,466 --> 03:53:21,767 AND INVESTMENT. 5766 03:53:21,767 --> 03:53:24,637 IT'S POSSIBLE TO GO BACK AND 5767 03:53:24,637 --> 03:53:26,172 RECURATE THAT DATA. 5768 03:53:26,172 --> 03:53:28,908 WE'VE DONE THAT IN FACEBASE, 5769 03:53:28,908 --> 03:53:30,776 WE'VE TAKEN EXISTING DATASETS 5770 03:53:30,776 --> 03:53:31,977 AND THROUGH SOME FOCUSED EFFORT 5771 03:53:31,977 --> 03:53:34,847 CURATED TO GIVE IT A NEW LIFE 5772 03:53:34,847 --> 03:53:37,883 BECAUSE IT WAS VALUABLE DATA. 5773 03:53:37,883 --> 03:53:39,852 SO IT DEPENDS ON HOW IT WAS 5774 03:53:39,852 --> 03:53:40,853 COLLECTED AND QUALITY OF THAT 5775 03:53:40,853 --> 03:53:44,724 DATA, BUT I DON'T THINK YOU HAVE 5776 03:53:44,724 --> 03:53:45,358 TO NECESSARILY START FROM 5777 03:53:45,358 --> 03:53:45,691 SCRATCH. 5778 03:53:45,691 --> 03:53:49,628 AND I THINK YOU NEED TO LOOK AT 5779 03:53:49,628 --> 03:53:50,730 A CASE-BY-CASE BASIS, VALUE 5780 03:53:50,730 --> 03:53:51,630 PROPOSITION HAVING THAT DATA, 5781 03:53:51,630 --> 03:53:54,166 AND AMOUNT OF WORK THAT WOULD BE 5782 03:53:54,166 --> 03:53:55,768 REQUIRED TO RECURATE IT. 5783 03:53:55,768 --> 03:53:58,170 IF IT'S POSSIBLE, TO RECURATE. 5784 03:53:58,170 --> 03:54:00,339 IN SOME CASES THE DETAILS THAT 5785 03:54:00,339 --> 03:54:02,875 YOU NEED ARE LOST TO THE 5786 03:54:02,875 --> 03:54:04,176 VAGARIES OF TIME BECAUSE IT 5787 03:54:04,176 --> 03:54:06,712 WASN'T COLLECTED UP TO CURRENT 5788 03:54:06,712 --> 03:54:07,813 FAIR STANDARDS, AND, YOU KNOW, 5789 03:54:07,813 --> 03:54:11,417 IT'S JUST NOT GOING TO BE 5790 03:54:11,417 --> 03:54:12,785 POSSIBLE TO REUSE THAT DATA, IN 5791 03:54:12,785 --> 03:54:15,588 WHICH CASE YOU HAVE TO MOVE 5792 03:54:15,588 --> 03:54:15,821 FORWARD. 5793 03:54:15,821 --> 03:54:23,796 >> THANK YOU. 5794 03:54:23,796 --> 03:54:24,463 JACQUES? 5795 03:54:24,463 --> 03:54:29,168 >> YES, SO SUPERB WORK, AXEL AND 5796 03:54:29,168 --> 03:54:29,602 TEAM. 5797 03:54:29,602 --> 03:54:34,006 YOU'RE REALLY NOT ONLY ABLE TO 5798 03:54:34,006 --> 03:54:35,107 REALLY LOOK IN DEPTH ON THE 5799 03:54:35,107 --> 03:54:39,145 CURRENT SITUATION BUT ALSO MAKE 5800 03:54:39,145 --> 03:54:40,546 VERY EXCELLENT RECOMMENDATIONS. 5801 03:54:40,546 --> 03:54:43,349 I AM PARTICULARLY INTERESTED 5802 03:54:43,349 --> 03:54:45,117 ABOUT THE WORKFORCE 5803 03:54:45,117 --> 03:54:45,551 RECOMMENDATION, YOUR 5804 03:54:45,551 --> 03:54:47,520 RECOMMENDATION NUMBER 4. 5805 03:54:47,520 --> 03:54:51,991 I CAN TELL YOU AND EVERYBODY 5806 03:54:51,991 --> 03:54:55,494 HERE THAT WE HAVE AN EFFORT HERE 5807 03:54:55,494 --> 03:54:57,997 TO RECRUIT DATA SCIENTIST HERE 5808 03:54:57,997 --> 03:55:03,569 AT MICHIGAN, AND IT WAS 5809 03:55:03,569 --> 03:55:04,804 EXTREMELY DIFFICULT BECAUSE SO 5810 03:55:04,804 --> 03:55:08,307 FEW THAT ARE ENGAGED IN THIS 5811 03:55:08,307 --> 03:55:12,144 FIELD WITH A FOCUS ON DOC 5812 03:55:12,144 --> 03:55:12,411 RESEARCH. 5813 03:55:12,411 --> 03:55:12,745 >> ABSOLUTELY. 5814 03:55:12,745 --> 03:55:13,779 >> SO I WONDER WHETHER, YOU 5815 03:55:13,779 --> 03:55:19,919 KNOW, WHAT TYPES OF MECHANISMS 5816 03:55:19,919 --> 03:55:27,460 NIDCR COULD PUT IN PLACE TO HELP 5817 03:55:27,460 --> 03:55:30,062 FOSTER THE TRAINING OF DATA 5818 03:55:30,062 --> 03:55:31,197 SCIENTISTS WITH RESEARCH. 5819 03:55:31,197 --> 03:55:32,064 >> JACQUES, THE DIFFERENCE 5820 03:55:32,064 --> 03:55:34,700 BETWEEN BEING FAMILIAR WITH THE 5821 03:55:34,700 --> 03:55:38,070 TERM, I WOULD AIM TO MYSELF, 5822 03:55:38,070 --> 03:55:40,072 DATA EXPERT, AND THE FIRST THING 5823 03:55:40,072 --> 03:55:42,141 I THINK WE HANDLED PRETTY WELL 5824 03:55:42,141 --> 03:55:44,009 IN A TIMELY MANNER ASKING ALL 5825 03:55:44,009 --> 03:55:45,945 THE T32 GRANTS TO MAKE SURE THEY 5826 03:55:45,945 --> 03:55:51,650 HAD A DATA SCIENCE COMPONENT, 5827 03:55:51,650 --> 03:55:52,318 RIGHT, LYNN? 5828 03:55:52,318 --> 03:55:52,551 >> YES? 5829 03:55:52,551 --> 03:55:54,153 >> THAT WOULDN'T MAKE A DATA 5830 03:55:54,153 --> 03:55:54,920 EXPERT. 5831 03:55:54,920 --> 03:55:58,157 YOU DEFINE DURATION OR FAIR 5832 03:55:58,157 --> 03:55:58,624 PRINCIPLES. 5833 03:55:58,624 --> 03:56:01,060 THERE'S DEFINITELY THE NEED 5834 03:56:01,060 --> 03:56:05,231 TRAIN ORAL HEALTH PROFESSIONALS 5835 03:56:05,231 --> 03:56:06,966 OR DENTISTS, DDS/PhDs CAN 5836 03:56:06,966 --> 03:56:07,733 EXPERTISE IN DATA SCIENCE, THAT 5837 03:56:07,733 --> 03:56:13,239 MIGHT HAVE TO BE A TARGETED T32 5838 03:56:13,239 --> 03:56:15,574 OR NEW T32s THAT WOULD INCLUDE 5839 03:56:15,574 --> 03:56:18,544 DATA SCIENCE AS A MAJOR ASPECT 5840 03:56:18,544 --> 03:56:19,678 OF TRAINING. 5841 03:56:19,678 --> 03:56:23,649 THERE ARE WHAT, 15 INSTITUTIONS 5842 03:56:23,649 --> 03:56:26,952 THAT OFFER IT AS GRADUATE 5843 03:56:26,952 --> 03:56:28,053 TRAINING, SO, YEAH. 5844 03:56:28,053 --> 03:56:29,154 THAT'S DEFINITELY ON THE TABLE. 5845 03:56:29,154 --> 03:56:31,757 >> IS THERE ANY CHANCE TO HAVE A 5846 03:56:31,757 --> 03:56:35,394 K AWARD MECHANISM THAT IS 5847 03:56:35,394 --> 03:56:37,530 TARGETED TO DATA SCIENTISTS? 5848 03:56:37,530 --> 03:56:38,197 >> YEAH, I -- 5849 03:56:38,197 --> 03:56:39,431 >> THE NOTICE OF SPECIAL 5850 03:56:39,431 --> 03:56:43,702 INTEREST THAT WE HAVE OUT THAT 5851 03:56:43,702 --> 03:56:46,906 WAS PUT FORTH BY NIDCR, ACTUALLY 5852 03:56:46,906 --> 03:56:48,774 APPLIED, IT IS ABOUT DATA 5853 03:56:48,774 --> 03:56:51,810 SCIENCE, IT APPLIES TO A WHOLE 5854 03:56:51,810 --> 03:56:53,045 FLEET OF FUNDING OPPORTUNITIES 5855 03:56:53,045 --> 03:56:56,081 OFFERED AND INCLUDES ALL OF THE 5856 03:56:56,081 --> 03:56:59,919 RESEARCH TRAINING AND CAREER 5857 03:56:59,919 --> 03:57:01,220 DEVELOPMENT FUNDING 5858 03:57:01,220 --> 03:57:02,388 OPPORTUNITIES. 5859 03:57:02,388 --> 03:57:03,289 IT'S APPLYING DATA SCIENCE TO 5860 03:57:03,289 --> 03:57:04,957 SICK REGIONS BUT THE DATA 5861 03:57:04,957 --> 03:57:10,563 SCIENCE CAN BE A TRAINING 5862 03:57:10,563 --> 03:57:13,966 COMPONENT IN THOSE APPLICATIONS, 5863 03:57:13,966 --> 03:57:14,266 FOR EXAMPLE. 5864 03:57:14,266 --> 03:57:14,600 >> THANK YOU. 5865 03:57:14,600 --> 03:57:16,835 >> THANK YOU. 5866 03:57:16,835 --> 03:57:17,036 LUCIA? 5867 03:57:17,036 --> 03:57:20,773 >> I WAS GOING TO GO BACK TO 5868 03:57:20,773 --> 03:57:23,075 YOUR QUESTION ON WHETHER THE 5869 03:57:23,075 --> 03:57:26,145 BEST SOLUTION IS FEDERATED OSH 5870 03:57:26,145 --> 03:57:27,012 CENTRALIZED, RIGHT? 5871 03:57:27,012 --> 03:57:32,484 AND YOU DID MENTION ALSO THE 5872 03:57:32,484 --> 03:57:33,352 FIELD OF TEMPOROMANDIBULAR JOINT 5873 03:57:33,352 --> 03:57:38,824 RESEARCH THAT NIDCR IS INVOLVED, 5874 03:57:38,824 --> 03:57:40,359 AND THE TMD INITIATIVE JUST 5875 03:57:40,359 --> 03:57:42,895 STARTING BUT HAS A BROAD VISION 5876 03:57:42,895 --> 03:57:47,366 OF INTEGRATING FROM BASIC SIZE 5877 03:57:47,366 --> 03:57:50,235 FROM T0 TO T4, AND WITHIN THE 5878 03:57:50,235 --> 03:57:52,838 HEAL INITIATIVE THERE ARE A 5879 03:57:52,838 --> 03:57:56,842 NUMBER OF DATA REPOSITORIES THAT 5880 03:57:56,842 --> 03:57:58,711 ARE SUPPORTED BY "HEAL." 5881 03:57:58,711 --> 03:58:00,713 AND WHETHER WE GO BACK TO DATA 5882 03:58:00,713 --> 03:58:04,049 THAT HAS ALREADY BEEN CREATED, 5883 03:58:04,049 --> 03:58:05,851 AS PAPERS ARE BEING PUBLISHED 5884 03:58:05,851 --> 03:58:07,786 AND JOURNALS ARE TAKEN 5885 03:58:07,786 --> 03:58:11,857 SERIOUSLY, THE DATA MANAGEMENT 5886 03:58:11,857 --> 03:58:12,825 AND SHARING PLAN, THE IMPORTANCE 5887 03:58:12,825 --> 03:58:16,762 IS THE VIEW OF HOW TO BRING 5888 03:58:16,762 --> 03:58:18,397 TOGETHER THIS DATA, MAINTAINING 5889 03:58:18,397 --> 03:58:22,234 THE FAIR PRINCIPLES THAT WE KNOW 5890 03:58:22,234 --> 03:58:25,437 IS IMPORTANT AND COORDINATED, SO 5891 03:58:25,437 --> 03:58:27,573 I DON'T THINK THERE IS ANY WAY 5892 03:58:27,573 --> 03:58:30,643 THAT THIS CAN BE REALLY DONE IN 5893 03:58:30,643 --> 03:58:32,945 A FULLY CENTRALIZED WAY BECAUSE 5894 03:58:32,945 --> 03:58:35,047 EVEN IN OUR RECOMMENDATION, OUR 5895 03:58:35,047 --> 03:58:36,448 WORKING GROUP RECOMMENDATION FOR 5896 03:58:36,448 --> 03:58:38,250 AN INFRASTRUCTURE THAT NEEDS TO 5897 03:58:38,250 --> 03:58:42,721 BE COST EFFECTIVE IN HOW NIDCR 5898 03:58:42,721 --> 03:58:45,991 CAN HANDLE THIS, RIGHT? 5899 03:58:45,991 --> 03:58:46,558 MAINTAINING COMPUTATIONAL 5900 03:58:46,558 --> 03:58:48,494 RESOURCES FOR VAST AMOUNTS OF 5901 03:58:48,494 --> 03:58:54,733 DATA CAN BE EXTREMELY EXPENSIVE. 5902 03:58:54,733 --> 03:58:57,169 AND HARD TO MAINTAIN TOO. 5903 03:58:57,169 --> 03:58:59,805 >> SO SOME OF THE CONVERSATION 5904 03:58:59,805 --> 03:59:02,975 CAN BE CONTINUED IN THE CLOSED 5905 03:59:02,975 --> 03:59:04,009 SESSION AMONG COUNCIL MEMBERS. 5906 03:59:04,009 --> 03:59:07,012 IF THERE ARE COMMENTS FROM THE 5907 03:59:07,012 --> 03:59:07,913 PUBLIC, OTHER PEOPLE AT THIS 5908 03:59:07,913 --> 03:59:11,316 POINT THAT WOULD BE HELPFUL. 5909 03:59:11,316 --> 03:59:14,153 OTHERWISE, WE CAN MOVE ON TO OUR 5910 03:59:14,153 --> 03:59:14,520 CLOSED SESSION. 5911 03:59:14,520 --> 03:59:18,524 >> I JUST WANT TO ADD, LYNN, TO 5912 03:59:18,524 --> 03:59:19,124 JACQUES' POINT ABOUT TRAINING, 5913 03:59:19,124 --> 03:59:24,430 IF YOU THINK OF IT, SEEMS LIKE 5914 03:59:24,430 --> 03:59:25,097 EVERYONE, EVERYONE, WITHOUT 5915 03:59:25,097 --> 03:59:29,268 EXCLUSION, EVEN PUBLIC HEALTH 5916 03:59:29,268 --> 03:59:29,868 COMMUNITY-BASED RESEARCHERS, 5917 03:59:29,868 --> 03:59:32,004 CERTAINLY THE BIOMEDICAL ONES, 5918 03:59:32,004 --> 03:59:34,873 BENCH BASED, NEEDS TO UNDERSTAND 5919 03:59:34,873 --> 03:59:36,108 BIOINFORMATICS AND DATA SCIENCE. 5920 03:59:36,108 --> 03:59:42,981 NEVER OF US GOT INSTRUCTION IN 5921 03:59:42,981 --> 03:59:44,983 GRADUATE SCHOOL BUT WE USE 5922 03:59:44,983 --> 03:59:48,187 STATION TRANSCRIPTOMICS, EVERY 5923 03:59:48,187 --> 03:59:49,888 ASPECT OF OUR SCIENCE. 5924 03:59:49,888 --> 03:59:52,091 OF COURSE TRAINING THE CURRENT 5925 03:59:52,091 --> 03:59:52,624 GENERATION, EDUCATING THE 5926 03:59:52,624 --> 03:59:55,494 EXISTING ONE IS GOING TO BE 5927 03:59:55,494 --> 03:59:58,530 CRITICAL, AT EVERY STAGE OF 5928 03:59:58,530 --> 03:59:59,565 CAREER DEVELOPMENT. 5929 03:59:59,565 --> 04:00:01,166 THAT'S SOMETHING BROAD THAT WE 5930 04:00:01,166 --> 04:00:01,934 WOULD COLLABORATE WITH OTHER 5931 04:00:01,934 --> 04:00:04,236 ORGANIZATIONS TO MAKE THAT 5932 04:00:04,236 --> 04:00:04,503 POSSIBLE. 5933 04:00:04,503 --> 04:00:05,738 >> IT WOULD BE OF INTEREST TO 5934 04:00:05,738 --> 04:00:09,074 KNOW IF THERE WILL BE LEADERSHIP 5935 04:00:09,074 --> 04:00:10,709 FROM NLM OR OTHER -- WHAT WILL 5936 04:00:10,709 --> 04:00:13,245 BE PROVIDED FROM OTHER SOURCES 5937 04:00:13,245 --> 04:00:18,050 AT NIH, BECAUSE IT IS A GLOBAL 5938 04:00:18,050 --> 04:00:18,283 PROBLEM. 5939 04:00:18,283 --> 04:00:20,185 >> AND THEN I'M SO GLAD TO SEE 5940 04:00:20,185 --> 04:00:20,886 YOU HERE. 5941 04:00:20,886 --> 04:00:24,423 THANK YOU FOR COMING INTO OUR 5942 04:00:24,423 --> 04:00:27,659 WORLD FROM YOUR REAL WORLD. 5943 04:00:27,659 --> 04:00:29,428 YOU KNOW THAT CLINICIANS ALSO 5944 04:00:29,428 --> 04:00:31,697 WHO HAVE ACCESS TO DENTAL 5945 04:00:31,697 --> 04:00:34,366 RECORDS AND INTERDENTAL RECORDS 5946 04:00:34,366 --> 04:00:37,069 HAVE TO HAVE SOME BASIC 5947 04:00:37,069 --> 04:00:39,571 CONTINUING EDUCATION COURSES ON 5948 04:00:39,571 --> 04:00:43,208 HOW THAT DATA ENTRY NEEDS TO BE 5949 04:00:43,208 --> 04:00:44,610 CURATED AND SENSIBLE SO THEY ARE 5950 04:00:44,610 --> 04:00:45,944 MEANINGFUL SO IT MAKES SENSE FOR 5951 04:00:45,944 --> 04:00:48,680 THOSE WHO ARE TRYING TO USE 5952 04:00:48,680 --> 04:00:49,948 COMBINED DATABASES. 5953 04:00:49,948 --> 04:00:51,517 PATIENT RECORDS HELP, ELECTRONIC 5954 04:00:51,517 --> 04:00:51,884 HEALTH RECORD. 5955 04:00:51,884 --> 04:00:52,718 >> YEAH, ABSOLUTELY, RENA. 5956 04:00:52,718 --> 04:00:55,254 THANK YOU FOR HAVING ME IN. 5957 04:00:55,254 --> 04:00:57,790 FIRST AND FOREMOST I HAVE TO 5958 04:00:57,790 --> 04:01:00,192 CALL OUT AXEL'S LEADERSHIP, A 5959 04:01:00,192 --> 04:01:03,061 PHENOMENAL JOB KEEPING US MOVING 5960 04:01:03,061 --> 04:01:03,295 FORWARD. 5961 04:01:03,295 --> 04:01:05,397 TO COMMENTING ON, YOU KNOW, THE 5962 04:01:05,397 --> 04:01:07,533 POINT YOU MADE, I THINK 5963 04:01:07,533 --> 04:01:09,701 INFORMATICS AND DATA SCIENCE HAS 5964 04:01:09,701 --> 04:01:11,436 BECOME A CRUCIAL BACKBONE OF 5965 04:01:11,436 --> 04:01:12,604 LEARNING, I THINK A LOT OF MY 5966 04:01:12,604 --> 04:01:15,541 COLLEAGUES HERE FROM THE WORKING 5967 04:01:15,541 --> 04:01:18,143 GROUP ALLUDED TO CENTRALIZED 5968 04:01:18,143 --> 04:01:21,547 VERSUS THE FEDERATED, HOW DO 5969 04:01:21,547 --> 04:01:23,749 WE -- MOVING FORWARD WHAT CAN WE 5970 04:01:23,749 --> 04:01:26,251 DO, WHAT CAN WE DO WITH ALREADY 5971 04:01:26,251 --> 04:01:27,586 INVESTED PROJECTS TO TRAINING 5972 04:01:27,586 --> 04:01:27,986 ASPECT. 5973 04:01:27,986 --> 04:01:32,191 I WANT TO COMMENT BRIEFLY, 5974 04:01:32,191 --> 04:01:33,392 QUICK, LYNN, I KNOW THERE'S A 5975 04:01:33,392 --> 04:01:35,027 FULL SESSION. 5976 04:01:35,027 --> 04:01:37,429 FROM A TRAINING PERSPECTIVE, 5977 04:01:37,429 --> 04:01:39,064 NIDCR DID COLLABORATE WITH NLM 5978 04:01:39,064 --> 04:01:42,801 IN THE PAST, AND THERE WERE KEY 5979 04:01:42,801 --> 04:01:44,536 POSTDOCTORAL AND UNDERGRADUATE 5980 04:01:44,536 --> 04:01:46,171 PROGRAMS THAT WERE BEING FUNDED. 5981 04:01:46,171 --> 04:01:50,809 I HAD THE OPPORTUNITY TO BE ONE 5982 04:01:50,809 --> 04:01:56,148 OF THE PROGRAM DIRECTORS, 5983 04:01:56,148 --> 04:01:57,950 TRAINING, WITH THE CLINIC. 5984 04:01:57,950 --> 04:02:02,087 IT TAKES A COMMUNITY NETWORK OF 5985 04:02:02,087 --> 04:02:03,055 OTHER BIOMEDICAL INFORMATICS 5986 04:02:03,055 --> 04:02:04,823 TRAINING PROGRAMS, WHICH GOES 5987 04:02:04,823 --> 04:02:10,829 FROM BIOINFORMATICS TO PUBLIC 5988 04:02:10,829 --> 04:02:13,599 HEALTH INFORMATICS AND 5989 04:02:13,599 --> 04:02:14,166 INCORPORATING ORAL AND 5990 04:02:14,166 --> 04:02:15,667 CRANIOFACIAL, IT'S ALMOST A 5991 04:02:15,667 --> 04:02:19,705 MATRIX SYSTEM, SO I COMPLETELY 5992 04:02:19,705 --> 04:02:20,572 AGREE THAT COLLABORATION NOT 5993 04:02:20,572 --> 04:02:22,875 ONLY WITHIN THE NIH PART OF 5994 04:02:22,875 --> 04:02:24,843 FUNDING BUT ALSO FOR DENTAL 5995 04:02:24,843 --> 04:02:27,479 SCHOOLS TO WORKING CLOSELY WITH 5996 04:02:27,479 --> 04:02:29,014 OTHER BIOMEDICAL INFORMATICS 5997 04:02:29,014 --> 04:02:30,749 PROGRAMS BECAUSE THE CHALLENGE 5998 04:02:30,749 --> 04:02:33,285 WE'VE SEEN IS THE MENTORS KIND 5999 04:02:33,285 --> 04:02:35,454 OF SHOULD HAVE THE BACKGROUND TO 6000 04:02:35,454 --> 04:02:38,056 BRING THAT ON THE NEXT 6001 04:02:38,056 --> 04:02:40,392 GENERATION, AND, YOU KNOW, IT 6002 04:02:40,392 --> 04:02:43,228 TAKES A GROUP OF DIFFERENT 6003 04:02:43,228 --> 04:02:44,196 SPECIALTIES, INFORMATICS, ORAL 6004 04:02:44,196 --> 04:02:46,632 HEALTH, ALL OF THAT COMING 6005 04:02:46,632 --> 04:02:47,366 TOGETHER. 6006 04:02:47,366 --> 04:02:52,771 FROM A DATA PERSPECTIVE CARL AND 6007 04:02:52,771 --> 04:02:57,676 LUCIA MENTIONED A MULTI-FOLD 6008 04:02:57,676 --> 04:02:58,377 APPROACH, NOT CENTRALIZED, 6009 04:02:58,377 --> 04:03:01,513 FEDERATED IS THE WAY TO GO IN MY 6010 04:03:01,513 --> 04:03:02,848 OPINION BUT ALSO PROBABLY TO 6011 04:03:02,848 --> 04:03:04,917 SOME EXTEND I DON'T WANT TO USE 6012 04:03:04,917 --> 04:03:08,854 THE WORD MANDATE BUT AS PART OF 6013 04:03:08,854 --> 04:03:10,489 NIH FUNDING MECHANISMS REALLY 6014 04:03:10,489 --> 04:03:15,193 LOOKING AT MAYBE A HUB AND SPOKE 6015 04:03:15,193 --> 04:03:17,496 MODEL, IF A SPECIFIC 6016 04:03:17,496 --> 04:03:19,364 ORGANIZATION IS A RECEIVER OF 6017 04:03:19,364 --> 04:03:22,935 MULTIPLE NIH FUNDING INCLUDING 6018 04:03:22,935 --> 04:03:26,438 NIDCR THERE NEEDS TO BE A LEVEL 6019 04:03:26,438 --> 04:03:28,974 OF OPERATION TO CURATING THE 6020 04:03:28,974 --> 04:03:30,609 PROJECTS THEY FUNDED WHICH CAN 6021 04:03:30,609 --> 04:03:33,679 BE FEDERATED ACROSS WITH A 6022 04:03:33,679 --> 04:03:36,882 COMMON DATA SCHEMA, YOU KNOW 6023 04:03:36,882 --> 04:03:38,750 WHAT AXEL ALLUDED TO, TOOLS, 6024 04:03:38,750 --> 04:03:42,788 FAIR PRINCIPLES, IT WILL TAKE 6025 04:03:42,788 --> 04:03:44,756 US A IN A FURTHER DIRECTION. 6026 04:03:44,756 --> 04:03:45,958 AS CARL MENTIONED WHAT HAPPENS 6027 04:03:45,958 --> 04:03:47,526 IS NOT WASTED. 6028 04:03:47,526 --> 04:03:50,262 THERE'S A LOT OF WELL THOUGHT 6029 04:03:50,262 --> 04:03:53,098 THROUGH NIDCR-FUNDED PROJECTS 6030 04:03:53,098 --> 04:03:54,399 THAT CAN BE HARMONIZED TO 6031 04:03:54,399 --> 04:03:54,833 ANOTHER STRATEGY. 6032 04:03:54,833 --> 04:03:57,169 THERE'S A LOT WE COULD DO TALK 6033 04:03:57,169 --> 04:03:57,469 ABOUT. 6034 04:03:57,469 --> 04:03:58,337 I'LL PAUSE HERE. 6035 04:03:58,337 --> 04:03:58,637 THANK YOU. 6036 04:03:58,637 --> 04:04:00,672 >> WE WANT TO STAY IN TOUCH WITH 6037 04:04:00,672 --> 04:04:02,207 ALL ON THE COMMITTEE. 6038 04:04:02,207 --> 04:04:04,376 YOUR WORK IS NOT DONE, WE STILL 6039 04:04:04,376 --> 04:04:05,711 NEED YOU TO STICK AROUND. 6040 04:04:05,711 --> 04:04:07,679 WE WOULD NEED YOU TO CONSULT 6041 04:04:07,679 --> 04:04:10,082 WITH AND HELP US THROUGH THIS 6042 04:04:10,082 --> 04:04:14,119 PROCESS IN A MORE SENSIBLE WAY. 6043 04:04:14,119 --> 04:04:15,988 OUR PLAN IS TO TAKE WHAT YOU'VE 6044 04:04:15,988 --> 04:04:18,290 GIVEN US AS THE ROADMAP, SO TO 6045 04:04:18,290 --> 04:04:20,359 SPEAK, REALLY CHEW ON IT. 6046 04:04:20,359 --> 04:04:22,427 THAT'S AN INTERNAL PROCESS AT 6047 04:04:22,427 --> 04:04:23,829 NIDCR. 6048 04:04:23,829 --> 04:04:24,963 WE'LL GO THROUGH WITH 6049 04:04:24,963 --> 04:04:26,264 CONSULTATIONS FROM EXPERTS 6050 04:04:26,264 --> 04:04:28,133 ACROSS FROM NLM ACROSS OUR DATA 6051 04:04:28,133 --> 04:04:31,303 SIGNS OFFICE. 6052 04:04:31,303 --> 04:04:34,039 AND THEN COME BACK, CONDITIONS 6053 04:04:34,039 --> 04:04:36,641 WE HOPE AT MAY COUNCIL WE WOULD 6054 04:04:36,641 --> 04:04:39,144 HAVE A VISION WELL DEFINED THAT 6055 04:04:39,144 --> 04:04:41,380 IS SMART, SPECIFIC, MEASURABLE, 6056 04:04:41,380 --> 04:04:42,547 SUSTAINABLE, RELEVANT IN 6057 04:04:42,547 --> 04:04:43,215 TIMELINE. 6058 04:04:43,215 --> 04:04:47,386 AND HAVE THAT ACTUALLY DRIVE THE 6059 04:04:47,386 --> 04:04:48,153 DDS OFFICE. 6060 04:04:48,153 --> 04:04:50,222 LOU WANG HAS BEEN WORKING ON 6061 04:04:50,222 --> 04:04:50,555 THAT. 6062 04:04:50,555 --> 04:04:52,958 SHE'S VERY MUCH IN TUNE WITH THE 6063 04:04:52,958 --> 04:04:53,825 WORKING GROUP'S RECOMMENDATION, 6064 04:04:53,825 --> 04:04:55,927 SO I THINK WE CAN MAKE THAT 6065 04:04:55,927 --> 04:04:56,194 DEADLINE. 6066 04:04:56,194 --> 04:05:01,199 AND THEN TAKE IT FROM THERE. 6067 04:05:01,199 --> 04:05:03,835 IT WILL INCLUDE TRAINING THE 6068 04:05:03,835 --> 04:05:05,137 WORKFORCE FOR THE FUTURE. 6069 04:05:05,137 --> 04:05:07,439 AND ENHANCING THE CURRENT 6070 04:05:07,439 --> 04:05:08,974 WORKFORCE ACTUALLY, YES. 6071 04:05:08,974 --> 04:05:12,811 THANK YOU VERY MUCH, VERY 6072 04:05:12,811 --> 04:05:13,445 HEARTFELT GRATITUDE FROM NIDCR, 6073 04:05:13,445 --> 04:05:15,447 FOR THE WORK YOU DID, ALL 6074 04:05:15,447 --> 04:05:18,517 VOLUNTEER HOURS, I WILL ADD. 6075 04:05:18,517 --> 04:05:21,887 THANK YOU VERY MUCH. 6076 04:05:21,887 --> 04:05:25,057 >> WOULD WE LIKE TO CLOSE THIS 6077 04:05:25,057 --> 04:05:25,290 SESSION? 6078 04:05:25,290 --> 04:05:25,824 >> YES. 6079 04:05:25,824 --> 04:05:27,259 >> THE OPEN SESSION, RENA? 6080 04:05:27,259 --> 04:05:28,693 >> YEAH. 6081 04:05:28,693 --> 04:05:30,529 I WOULD SAY THAT WE HAVE A LOT 6082 04:05:30,529 --> 04:05:32,831 AHEAD OF US. 6083 04:05:32,831 --> 04:05:35,133 WE COVERED I THINK IN GENERAL 6084 04:05:35,133 --> 04:05:37,135 HOW THE WORLD IS CHANGING, HOW 6085 04:05:37,135 --> 04:05:40,405 IT'S GOING TO INFLUENCE NOT JUST 6086 04:05:40,405 --> 04:05:43,341 OUR FUNDING SITUATION BUT ALSO 6087 04:05:43,341 --> 04:05:45,444 OUR ATTITUDES ABOUT SCIENCE. 6088 04:05:45,444 --> 04:05:47,946 AND THAT IS IMPORTANT FOR US TO 6089 04:05:47,946 --> 04:05:52,017 KIND OF KEEP IN STEP WITH EACH 6090 04:05:52,017 --> 04:05:53,318 OTHER, WITH NIDCR. 6091 04:05:53,318 --> 04:05:54,586 YOU'RE THE EXTRAMURAL COMMUNITY 6092 04:05:54,586 --> 04:05:55,420 WE VALUE TREMENDOUSLY. 6093 04:05:55,420 --> 04:05:58,356 AND I CAN TELL YOU NONE OF THE 6094 04:05:58,356 --> 04:05:59,791 INITIATIVES THAT WERE LAUNCHED 6095 04:05:59,791 --> 04:06:02,394 LAST YEAR OR ANY OF THE 6096 04:06:02,394 --> 04:06:03,061 SCIENTIFIC ACCOMPLISHMENTS OF 6097 04:06:03,061 --> 04:06:04,396 BOTH INTRAMURAL AND EXTRAMURAL 6098 04:06:04,396 --> 04:06:06,364 COULD NOT HAVE -- WOULD NOT HAVE 6099 04:06:06,364 --> 04:06:07,899 HAPPENED, I CAN ASSURE YOU, 6100 04:06:07,899 --> 04:06:10,202 WOULD NOT HAVE HAPPENED WITHOUT 6101 04:06:10,202 --> 04:06:14,106 STAFF AND STAFF AT EVERY LEVEL 6102 04:06:14,106 --> 04:06:15,340 OF OUR ORGANIZATION. 6103 04:06:15,340 --> 04:06:18,176 FROM THOSE WHO RUN CORE 6104 04:06:18,176 --> 04:06:21,113 FACILITIES AT NIDCR, COLLEAGUES 6105 04:06:21,113 --> 04:06:22,547 ACROSS NIH, STAFFERS, PROGRAM 6106 04:06:22,547 --> 04:06:25,183 OFFICERS, AND EXECUTIVE TEAMS. 6107 04:06:25,183 --> 04:06:27,352 SO WE -- I'M FEELING VERY GOOD. 6108 04:06:27,352 --> 04:06:30,222 IT'S HARD TO GAIN A PERSPECTIVE 6109 04:06:30,222 --> 04:06:32,591 AS TO WHAT PROGRESS REALLY IS 6110 04:06:32,591 --> 04:06:35,127 ABOUT UNTIL WE SEE HOW PATIENTS 6111 04:06:35,127 --> 04:06:36,328 BENEFIT FROM IT. 6112 04:06:36,328 --> 04:06:38,497 AND I REALLY AM FEELING THAT 6113 04:06:38,497 --> 04:06:40,465 GOAL IS FAR MORE REALISTIC TODAY 6114 04:06:40,465 --> 04:06:41,133 THAN IT WAS BEFORE. 6115 04:06:41,133 --> 04:06:45,637 SO THAT WOULD BE MY GUIDING HOPE 6116 04:06:45,637 --> 04:06:46,505 AND LIGHT. 6117 04:06:46,505 --> 04:06:48,573 THANK YOU FOR BEING HERE. 6118 04:06:48,573 --> 04:06:51,176 PLEASE MAKE AN ATTEMPT TO COME 6119 04:06:51,176 --> 04:06:52,410 IN MAY FOR OUR IN-PERSON -- IT'S 6120 04:06:52,410 --> 04:06:54,980 A BEAUTIFUL TIME OF YEAR, 6121 04:06:54,980 --> 04:06:55,780 IN-PERSON COUNCIL. 6122 04:06:55,780 --> 04:07:01,086 I THINK IT'S STILL COUNCIL HERE, 6123 04:07:01,086 --> 04:07:03,155 AND OBSERVERS OR OTHERS WOULD BE 6124 04:07:03,155 --> 04:07:04,923 VIRTUALLY CONNECTING. 6125 04:07:04,923 --> 04:07:06,458 I'M HOPING DR. BERTAGNOLLI WILL 6126 04:07:06,458 --> 04:07:08,260 MEET US IN PERSON, MEET YOU IN 6127 04:07:08,260 --> 04:07:10,896 PERSON BECAUSE SHE PLANS TO BE 6128 04:07:10,896 --> 04:07:12,197 THERE GIVEN HER SCHEDULE. 6129 04:07:12,197 --> 04:07:15,567 AND THAT WE'LL HAVE ANOTHER 6130 04:07:15,567 --> 04:07:17,302 EXCITING LINEUP OF SPEAKERS TO 6131 04:07:17,302 --> 04:07:20,939 TALK ABOUT WHAT I THINK ARE 6132 04:07:20,939 --> 04:07:22,040 EMERGING FRONTS IN OUR FIELD. 6133 04:07:22,040 --> 04:07:23,341 THANK YOU VERY MUCH. 6134 04:07:23,341 --> 04:07:26,178 HAVE A WONDERFUL DAY, ALL THOSE 6135 04:07:26,178 --> 04:07:34,152 WHO HAVE TO SIGN OFF. 6136 04:07:34,152 --> 04:07:37,222 [END OF PROGRAM] 6137 04:07:37,222 --> 04:07:43,261 6138 04:07:43,261 --> 04:07:53,305