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WELCOME TO DAY 2 OF THE ADVISORY

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COUNCIL MEETING.

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WE HAD SOME GREAT PRESENTATIONS

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AND DISCUSSION YESTERDAY.

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I JUST WANTED TO INVITE COUNCIL

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MEMBERS, IF YOU REQUIRE ANY

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ADDITIONAL INFORMATION OR WANT

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TO DISCUSS ANY OF THOSE TOPICS,

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WITH US, PLEASE JUST LET US KNOW

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AND WE'RE HAPPY TO DO SO.

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AND SO TODAY I AM VERY HAPPY TO

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WELCOME TO OUR COUNCIL MEETING

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DR. BRUCE REED, CSR DEPUTY

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DIRECTOR.

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IN HIS ROLE HE OVERSEES

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ACTIVITIES AIMED AT ADVANCING

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THE CSR DIRECTOR'S STRATEGIC

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VISION, HAS BEEN INSTRUMENTAL IN

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STUDY SECTION EVALUATION THROUGH

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CSR'S QUALITY REVIEW AND DEVELOP

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TARGETED OUTREACH.

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HE'S HERE ARE US TODAY TO UPDATE

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US ON CSR PROGRAMS AND VERY MUCH

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LOOKING FORWARD TO HEARING WHAT

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YOU HAVE TO SAY, BRUCE.

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>> THANKS VERY MUCH.

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I APPRECIATE THE INVITATION AND

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A CHANCE TO TALK TO YOU ABOUT

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PEER REVIEW.

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SO, LET ME BRING UP MY SLIDES.

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JUST A SECOND HERE.

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OKAY.

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YOU SHOULD BE SEEING MY TITLE 

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SLIDE.

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YES?

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>> YES.

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YOU'RE FINE.

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>> OKAY.

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ALL RIGHT.

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SO, THANKS.

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I'M GOING TO BE TALKING ABOUT

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WHAT WE UNDERSTAND ABOUT BIAS

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AND PEER REVIEW AT THE NIH, AND

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WHAT CSR IS DOING TO COMBAT IT.

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SO, LET'S SEE.

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LET'S GET THE SLIDES TO 

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ADVANCE.

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LET'S START WITH DATA AND WHAT

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THE LITERATURE SAYS FOCUSING ON,

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AGAIN, PEER REVIEW AT THE NIH.

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AS PROBABLY ALL OF YOU KNOW, IN

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2011 DONNA GINTHER PUBLISHED A

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PAPER THAT SHOWED AFRICAN

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AMERICAN SCIENTISTS ARE

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SUBSTANTIALLY LESS LIKELY TO BE

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AWARDED AN R01 COMPARED TO WHITE

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COUNTERPARTS.

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THIS BASIC OBSERVATION WAS

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REPLICATED, IT WAS EXTENDED IN

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MULTIPLE PAPERS OVER THE ENSUING

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ZEK AID.

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THIS GAP IN FUNDING IS

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SUBSTANTIAL.

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IT'S ON THE ORDER OF 50%.

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AT LEAST THROUGH 2020, IT HAD

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NOT IMPROVED AT ALL.

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SO, PROBABLY BECAUSE AT THE NIH

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OVERALL, THERE IS A CLOSE

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RELATIONSHIP BETWEEN REVIEW

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OUTCOMES AND FUNDING DECISIONS,

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MANY PEOPLE ASSUMED THAT IF

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THERE'S A FUNDING DISPARITY,

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MUST BE DUE TO BIAS IN PEER

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REVIEW.

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GINTHER WAS CAUTIOUS AND

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SKEPTICAL OF THAT EXPLANATION,

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BUT MANY OTHERS WERE NOT.

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AND THERE HAVE BEEN MANY

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COMMENTATORS THAT -- I'M PICKING

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UP SOMEBODY.

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ANYWAY, SO MANY COMMENTATORS

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HAVE ARGUED THAT PEER REVIEW IS

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RACIALLY BIASED, FOR EXAMPLE

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THIS CARTOON COMES FROM THE

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STEVENS ET AL. COMMENTARY IN

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"CELL" LARS YEAR, YOU CAN SEE

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THE ARGUMENT THAT THE NIH RACIAL

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FUNDING DISPARITY IS A RESULT OF

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BIASED PEER REVIEWERS PUSHING 

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THEIR AFRICAN AMERICAN

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COLLEAGUES OFF THE CLIFFS OF

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ACADEMIA.

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THE OBSERVATION WAS ABOUT

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FUNDING GAP, THE INTERPRETATION

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WAS THAT IT WAS REVIEW BIAS.

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BUT THIS PAPER WHICH DID COME

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OUT OF THE NIH PURPORTED TO FIND

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THERE IS REVIEWER BIAS, NOT ON

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THE BASIS OF RACE PER SE BUT ON

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BASIS OF TOPIC CHOICE.

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SO HOPP AND COLLEAGUES MADE A

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NUMBER OF IMPORTANT

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OBSERVATIONS, SO, ONE WAS THAT

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APPLICATIONS FROM AFRICAN

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AMERICAN SCIENTISTS ARE

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CONCENTRATED IN A SMALL NUMBER

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OF TOPICS.

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SO, WHAT THEY DID WAS THEY TOOK

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A LARGE BATCH OF NIH

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APPLICATIONS, AND USING NATURAL

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LANGUAGE PROCESSING THEY GROUPED

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IT INTO -- GROUPED THEM INTO

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ABOUT 150 TOPIC CLUSTERS.

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THEN THEY LOOKED AT THE PERCENT

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OF APPLICATIONS WITHIN EACH OF

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THOSE CLUSTERS THAT CAME FROM

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AFRICAN AMERICAN SCIENTISTS.

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AND THAT'S THIS VERY SKEWED

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DISTRIBUTION THAT YOU'RE LOOKING

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AT HERE.

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SO, OBVIOUSLY THERE'S A LOT OF

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TOPICS WHERE THE REPRESENTATION

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OF AFRICAN AMERICAN SCIENTISTS 

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IS VANISHING ILY SMALL BUT

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THERE'S A NUMBER OF APPLICATIONS

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FROM BLACK SCIENTISTS.

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IF YOU TAKE THE FIRST 15 OF

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THESE TOPICS, THOSE 15 TOPICS

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ALONE ACCOUNT FOR OVER 50% OF

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THE APPLICATIONS THAT COME FROM

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BLACK SCIENTISTS.

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SO, LET'S JUST CALL THOSE 

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AFRICAN AMERICAN PREFERRED

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TOPICS.

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SO, HOPP AND COLLEAGUES ALSO

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OBSERVED THAT THE AWARD RATES

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DIFFER FOUR-FOLD ACROSS THESE

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DIFFERENT TOPICS.

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AND BASICALLY, THE AWARD RATES

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FOR THESE TOPICS, THESE FAVORED

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TOPICS, ARE RELATIVELY LOW.

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SO, TOPIC CHOICE ALONE IN THEIR

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ANALYSES ACCOUNTED FOR OVER 20%

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OF THE NIH FUNDING GAP.

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AND THERE OF THEIR BOTTOM LINE

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CONCLUSION WAS THAT THE REASON

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WAS THAT WAS BIAS ON THE PART OF

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REVIEWERS, THAT REVIEWERS SEEMED

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TO PREFER CERTAIN TOPICS OVER

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OTHERS.

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SO, THEY WERE RIGHT ABOUT ALL

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THEIR FIRST OBSERVATIONS BUT

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THEY WERE WRONG ABOUT THIS

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CONCLUSION.

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AND THEY WERE WRONG ABOUT IT

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BECAUSE THEY LEFT OUT ONE

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IMPORTANT VARIABLE.

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AND THAT WAS I.C. -- INDIVIDUAL

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I.C. AWARD RATES.

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IN THIS 2021 PAPER MIKE LAUER

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AND YOU OF -- AND COLLEAGUES

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TOOK ANOTHER LOOK AT THE EXACT

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SAME DATASET THAT HOPP USED.

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WHEN YOU DO THAT HERE IS WHAT

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YOU FIND.

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THREE THINGS.

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AFRICAN AMERICAN PREFERRED

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TOPICS ARE UNEVENLY DISTRIBUTED

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ACROSS THE I.C.s.

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OF COURSE, FUNDING RATES ACROSS

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THE I.C.s ALSO VARY,

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THREE-FOLD.

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AND AFRICAN AMERICAN PREFERRED

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TOPICS ARE PRIMARILY FUNDED BY

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I.C.s WITH RELATIVELY LOW

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FUNDING RATES.

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IF YOU MAP THIS OUT, THIS IS

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WHAT IT LOOKS LIKE.

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SO, ON HERE IS THE PERCENTAGE OF

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APPLICATIONS THEY GET THAT COME

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ON THESE AFRICAN AMERICAN

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PREFERRED TOPICS.

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AND ON THE ORDINANT YOU HAVE THE

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I.C. AWARD RATE.

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THERE ARE SOME I.C.s THAT GET

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RELATIVELY LARGE NUMBER OF 

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APPLICATIONS ON THESE TOPICS AND

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THEIR AWARD RATES ARE PRETTY

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LOW.

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ON THE OTHER HAND YOU HAVE OTHER

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INSTITUTES THAT GET VERY FEW

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APPLICATIONS ON THESE TOPICS AND

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HAVE RELATIVELY HIGH AWARD

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RATES.

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AND SO WHEN YOU TAKE THIS INTO

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ACCOUNT, THAT EXPLAINS THIS 

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TOPIC CHOICE EFFECT.

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AND SO THE CONCLUSION OF THE

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LAUER PAPER WAS THAT, YES, TOPIC

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CHOICE MATTERS, BUT PRIMARILY

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BECAUSE OF THEIR ASSIGNMENT TO

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THE I.C.s NOT TO PEER REVIEW

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PREFERENCES.

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THEY DID LOOK SPECIFIC LIVE AT

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PEER REVIEW OUTCOMES FOR

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PREFERRED VERSUS OTHER TOPICS,

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SAW NO DIFFERENCE AT ALL.

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YOU DON'T SEE EVIDENCE OF

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REVIEWER BIAS ON THE BASIS OF

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TOPIC CHOICE, BUT BACK TO THE

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SORT OF CORE ARGUMENT, IS THERE

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IDENTITY-BASED BIAS IN NIH PEER

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REVIEW?

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THERE'S NOT A LOT OF LITERATURE

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ON IT.

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THIS STUDY WHICH WE CALL CSR'S

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ANONYMIZATION STUDY PUBLISHED

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LAST YEAR IS A LARGE SCALE

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EXPERIMENTAL TEST OF TRYING TO

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GET AT THAT ISSUE.

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SO, LET ME WALK YOU THROUGH IT.

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SO, THIS STUDY USED THREE SETS

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OF REAL NIH APPLICATIONS.

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400 R01s CAME FROM BLACK

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P.I.s, AND THERE WERE TWO

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COMPARATOR SETS.

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THERE WERE 400 FROM WHITE P.I.

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P.I.s MATCHED TO BLACK P.I.s

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ON REVIEW RELEVANT FEATURES, AND

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ANOTHER RANDOMLY SELECTED SET OF

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400 FROM WHITE P.I.s.

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IT TOOK THESE ACTUAL

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APPLICATIONS, THEY WERE REDACTED

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BY STUDY PERSONNEL TO REMOVE

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INDICATORS OF PERSONAL IDENTITY

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AND INSTITUTIONAL AFFILIATION.

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THEN THE STANDARD FORMAT AND

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REDACTED VERSIONS UNDERWENT

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SIMULATED PEER REVIEW.

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WE LOOKED AT PEER REVIEW

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OUTCOMES.

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AND REVIEWERS WERE ASKED ALSO TO

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GUESS THE P.I. RACE, GENDER, AND

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NAME AFTER THEY COMPLETED THEIR

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CRITIQUES.

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SO, WHAT WERE THE EFFECTS OF

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REDACTION?

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A COUPLE OF KEY FINDINGS.

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SO, FIRST, REDACTION REDUCED THE

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ACCURACY OF REVIEWERS' GUESSES

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OF P.I. RACE FOR BLACK BUT NOT

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FOR WHITE APPLICANTS.

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SO, IF YOU LOOK AT THIS TABLE,

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HERE'S ACTUAL P.I. RACE.

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AND SO YOU SEE THAT WITH

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STANDARD APPLICATIONS, THE

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REVIEWERS WERE ABLE TO

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ACCURATELY GUESS THE RACE OF THE

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P.I. 59% OF THE TIME.

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WHEN INFORMATION WAS REDACTED

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THAT FELL TO ABOUT 30%.

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SO IT DID SIGNIFICANTLY REDUCE

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REVIEWERS' KNOWLEDGE OF RACE FOR

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BLACK APPLICANTS.

265
00:10:56,560 --> 00:10:57,800
FOR WHITE APPLICANTS, WHETHER

266
00:10:57,800 --> 00:11:00,000
IT'S MATCHED OR RANDOM SAMPLE

267
00:11:00,000 --> 00:11:01,080
LOOKING AT STANDARD APPLICATIONS

268
00:11:01,080 --> 00:11:03,600
REVIEWERS WERE EXTREMELY GOOD AT

269
00:11:03,600 --> 00:11:05,600
GUESSING THE RACE CORRECTLY, AND

270
00:11:05,600 --> 00:11:07,440
WITH REDACTED APPLICATIONS THEY

271
00:11:07,440 --> 00:11:09,000
WERE EXTREMELY GOOD AT

272
00:11:09,000 --> 00:11:10,480
ACCURATELY GUESSING THE RACE.

273
00:11:10,480 --> 00:11:13,400
SO MADE NO DIFFERENCE THERE.

274
00:11:13,400 --> 00:11:18,240
SO WHAT ABOUT REVIEW OUTCOMES?

275
00:11:18,240 --> 00:11:21,400
REDACTION MADE SCORES WORSE FOR

276
00:11:21,400 --> 00:11:24,680
WHITE APPLICANTS BUT NOT FOR

277
00:11:24,680 --> 00:11:25,440
BLACK APPLICANTS.

278
00:11:25,440 --> 00:11:28,880
SO, WHAT YOU'RE LOOKING AT HERE

279
00:11:28,880 --> 00:11:31,400
ARE PLOTS OF THE DATA, THE

280
00:11:31,400 --> 00:11:35,000
YELLOW BOXES ARE FOR THE

281
00:11:35,000 --> 00:11:36,640
STANDARD FORMAT APPLICATIONS,

282
00:11:36,640 --> 00:11:40,920
BLUE BOXES ARE FOR THE REDACTED.

283
00:11:40,920 --> 00:11:43,760
THE SCALE HERE IS THE STANDARD

284
00:11:43,760 --> 00:11:46,680
NIH SCALE THAT WE USE FOR

285
00:11:46,680 --> 00:11:48,160
OVERALL IMPACT.

286
00:11:48,160 --> 00:11:51,560
1 IS BEST, 9 IS WORST.

287
00:11:51,560 --> 00:11:56,440
AND SO IF YOU LOOK OVER HERE AT

288
00:11:56,440 --> 00:11:58,760
THE FAR LEFT COLUMN, THESE ARE

289
00:11:58,760 --> 00:11:59,440
THE RESULTS FOR APPLICATIONS

290
00:11:59,440 --> 00:12:00,720
FROM BLACK P.I.s.

291
00:12:00,720 --> 00:12:03,360
YOU CAN SEE REDACTION MADE NO

292
00:12:03,360 --> 00:12:03,880
DIFFERENCE, NO DIFFERENCE

293
00:12:03,880 --> 00:12:06,000
WHATSOEVER, IN THE SCORES FOR

294
00:12:06,000 --> 00:12:07,000
THESE APPLICATIONS.

295
00:12:07,000 --> 00:12:08,600
BUT IT DID MAKE A DIFFERENCE FOR

296
00:12:08,600 --> 00:12:10,360
BOTH OF THE WHITE SAMPLES.

297
00:12:10,360 --> 00:12:12,320
HERE IS THE MATCHED SAMPLE FOR

298
00:12:12,320 --> 00:12:14,200
WHITE APPLICATIONS, AND YOU CAN

299
00:12:14,200 --> 00:12:16,640
SEE THE REDACTION, THE REDACTED

300
00:12:16,640 --> 00:12:18,240
SCORES GET HIGHER, THAT'S WORSE.

301
00:12:18,240 --> 00:12:22,600
AGAIN FOR THE RANDOM SAMPLE, 

302
00:12:22,600 --> 00:12:24,880
REDACTION MADE THE SCORES WORSE.

303
00:12:24,880 --> 00:12:26,400
SO THE OTHER THING I'LL POINT

304
00:12:26,400 --> 00:12:28,880
OUT IT'S HARD LOOKING AT RAW

305
00:12:28,880 --> 00:12:30,480
DATA HERE BUT OVERALL, THE

306
00:12:30,480 --> 00:12:31,840
APPLICATIONS FROM WHITE P.I.s

307
00:12:31,840 --> 00:12:34,920
DID SCORE BETTER THAN THOSE FROM

308
00:12:34,920 --> 00:12:44,000
BLACK P.I.s, Xs ARE MEANS,

309
00:12:44,000 --> 00:12:45,080
BOTH WHITE SAMPLES SCORED

310
00:12:45,080 --> 00:12:46,400
SOMEWHAT BETTER AND REDACTION

311
00:12:46,400 --> 00:12:48,520
DOES NOT ELIMINATE THAT

312
00:12:48,520 --> 00:12:53,600
DIFFERENCE BUT CUTS IT ABOUT IN

313
00:12:53,600 --> 00:12:53,960
HALF.

314
00:12:53,960 --> 00:12:56,480
SO, WHAT DO THESE DATA SAY ABOUT

315
00:12:56,480 --> 00:13:00,600
THE NATURE OF BIAS IN NIH PEER

316
00:13:00,600 --> 00:13:01,000
REVIEW?

317
00:13:01,000 --> 00:13:03,600
YOU SEE VERY LITTLE EVIDENCE OF

318
00:13:03,600 --> 00:13:05,440
ANTI-BLACK BIAS IN REVIEW BASED

319
00:13:05,440 --> 00:13:09,160
ON P.I. RACE PER SE.

320
00:13:09,160 --> 00:13:10,640
HOWEVER, YOU DO SEE THE

321
00:13:10,640 --> 00:13:12,240
APPLICATIONS FROM WHITE P.I.s

322
00:13:12,240 --> 00:13:13,080
SCORED BETTER THAN THOSE FROM

323
00:13:13,080 --> 00:13:16,400
BLACK P.I.s, AND THAT

324
00:13:16,400 --> 00:13:17,120
REDACTION REDUCES THAT

325
00:13:17,120 --> 00:13:17,400
ADVANTAGE.

326
00:13:17,400 --> 00:13:20,640
SO WHAT COULD BE GOING ON?

327
00:13:20,640 --> 00:13:24,240
SO, ONE EXPLANATION IS HALO

328
00:13:24,240 --> 00:13:24,480
EFFECT.

329
00:13:24,480 --> 00:13:25,520
BY HALO EFFECT THE MEAN THE

330
00:13:25,520 --> 00:13:27,840
SITUATION OF GLOW OF A BIG NAME

331
00:13:27,840 --> 00:13:29,480
LEADS THE REVIEWER TO GIVE

332
00:13:29,480 --> 00:13:30,800
OVERLY GOOD SCORES.

333
00:13:30,800 --> 00:13:33,080
AND WHO IS GOING TO BENEFIT FROM

334
00:13:33,080 --> 00:13:33,320
THAT?

335
00:13:33,320 --> 00:13:34,400
THAT'S GOING TO BENEFIT THE

336
00:13:34,400 --> 00:13:35,720
PEOPLE WITH THE BIG NAMES.

337
00:13:35,720 --> 00:13:38,800
WHO ARE THOSE?

338
00:13:38,800 --> 00:13:40,320
THOSE ARE TYPICALLY SENIOR

339
00:13:40,320 --> 00:13:43,080
WELL-ESTABLISHED P.I.s, AND

340
00:13:43,080 --> 00:13:43,560
THEY ARE PREDOMINANTLY

341
00:13:43,560 --> 00:13:46,320
NON-HISPANIC WHITE P.I.s.

342
00:13:46,320 --> 00:13:49,400
AND SO THIS IS A FORM OF BIAS,

343
00:13:49,400 --> 00:13:53,240
THIS VOTING ON THE BASIS OF P.I.

344
00:13:53,240 --> 00:13:55,720
OR INSTITUTIONAL REPUTATION IS A

345
00:13:55,720 --> 00:14:03,320
FORM OF BIAS, WHICH TENDS TO

346
00:14:03,320 --> 00:14:03,840
FAVOR WELL-ESTABLISHED

347
00:14:03,840 --> 00:14:07,240
NON-HISPANIC WHITE P.I.s.

348
00:14:07,240 --> 00:14:10,080
AND SO THE POINT IS THAT WITH

349
00:14:10,080 --> 00:14:11,840
REDACTION, WHEN YOU TAKE AWAY

350
00:14:11,840 --> 00:14:13,160
THAT ADVANTAGE, THE SCORES GET

351
00:14:13,160 --> 00:14:13,600
WORSE.

352
00:14:13,600 --> 00:14:16,080
AND THAT COULD EXPLAIN THE

353
00:14:16,080 --> 00:14:19,080
FINDINGS THAT YOU SEE.

354
00:14:19,080 --> 00:14:21,080
SO, THIS KIND OF PHENOMENON

355
00:14:21,080 --> 00:14:22,480
COULD BE PARTICULARLY IMPORTANT

356
00:14:22,480 --> 00:14:25,680
AT THE NIH BECAUSE TWO OF THE

357
00:14:25,680 --> 00:14:27,600
FIVE REVIEW CRITERIA, THE FIVE

358
00:14:27,600 --> 00:14:30,240
REVIEW CRITERIA WHICH ARE

359
00:14:30,240 --> 00:14:32,560
LEGALLY REQUIRED OF US, TWO OF

360
00:14:32,560 --> 00:14:34,360
THEM ARE INVESTIGATOR AND

361
00:14:34,360 --> 00:14:35,000
ENVIRONMENT.

362
00:14:35,000 --> 00:14:38,400
SO, REVIEWERS HAVE TO TAKE THESE

363
00:14:38,400 --> 00:14:40,280
FACTORS INTO ACCOUNT IN JUDGING

364
00:14:40,280 --> 00:14:43,240
THE OVERALL IMPACT OF THE GRANT,

365
00:14:43,240 --> 00:14:46,280
AND SO IT'S A PARTICULAR ISSUE

366
00:14:46,280 --> 00:14:46,840
FOR US.

367
00:14:46,840 --> 00:14:55,160
SO, WHAT CAN WE DO ABOUT THIS?

368
00:14:55,160 --> 00:14:56,920
CSR HAS TAKEN MULTIPLE STEPS TO

369
00:14:56,920 --> 00:15:00,440
COMBAT THIS SORT OF BIAS WHICH

370
00:15:00,440 --> 00:15:01,960
JUST TO BE CLEAR I THINK

371
00:15:01,960 --> 00:15:03,800
REPUTATIONAL BIAS IS THE MOST

372
00:15:03,800 --> 00:15:04,760
SIGNIFICANT, MOST COMMON KIND OF

373
00:15:04,760 --> 00:15:10,800
BIAS WE SEE IN PEER REVIEW AT

374
00:15:10,800 --> 00:15:11,000
NIH.

375
00:15:11,000 --> 00:15:13,360
AND IT'S OFTEN AN EXPLICIT BIAS.

376
00:15:13,360 --> 00:15:17,240
SO, WHAT CAN YOU DO ABOUT IT?

377
00:15:17,240 --> 00:15:17,920
THESE ARE THE INITIATIVES.

378
00:15:17,920 --> 00:15:21,080
SO ONE OF THE THINGS THAT WE'RE

379
00:15:21,080 --> 00:15:24,440
LOOKING AT IS PARTIALLY BLINDED

380
00:15:24,440 --> 00:15:26,400
REVIEW PROCESSES.

381
00:15:26,400 --> 00:15:31,200
SO, FOR EXAMPLE, WE HAVE A

382
00:15:31,200 --> 00:15:33,240
THREE-YEAR PILOT UNDERWAY, IN

383
00:15:33,240 --> 00:15:34,800
CONJUNCTION WITH THE COMMON

384
00:15:34,800 --> 00:15:38,120
FUND, LOOKING AT THE REVIEW OF

385
00:15:38,120 --> 00:15:41,360
THE NIH DIRECTOR'S

386
00:15:41,360 --> 00:15:45,200
TRANSFORMATIVE RESEARCH AWARDS.

387
00:15:45,200 --> 00:15:48,160
SO, THIS RFA GETS A LARGE NUMBER

388
00:15:48,160 --> 00:15:50,040
OF APPLICATIONS ON A HUGE RANGE

389
00:15:50,040 --> 00:15:50,840
OF SCIENCE.

390
00:15:50,840 --> 00:15:54,520
AND WE REVIEW IT USING AN

391
00:15:54,520 --> 00:15:55,160
EDITORIAL BOARD FORMAT.

392
00:15:55,160 --> 00:15:56,600
THE KEY THING TO UNDERSTAND IS

393
00:15:56,600 --> 00:15:59,080
THAT IN THIS FORMAT YOU TAKE

394
00:15:59,080 --> 00:16:01,640
THIS LARGE INITIAL POOL OF

395
00:16:01,640 --> 00:16:05,520
APPLICATIONS, AND IN A SERIES OF

396
00:16:05,520 --> 00:16:07,960
STEPS IT'S WINNOWED DOWN TO A

397
00:16:07,960 --> 00:16:10,360
SMALL SET OF FINALISTS, AND ONLY

398
00:16:10,360 --> 00:16:11,920
THE FINALISTS GO FORWARD TO THE

399
00:16:11,920 --> 00:16:13,360
MEETING WHERE EVERYONE IS

400
00:16:13,360 --> 00:16:15,840
DISCUSSED AND SCORED.

401
00:16:15,840 --> 00:16:18,440
SO, IN THIS PILOT, ALL OF THOSE

402
00:16:18,440 --> 00:16:19,880
INITIAL STEPS PRIOR TO THE

403
00:16:19,880 --> 00:16:21,080
MEETING, THE WHOLE PROCESS OF

404
00:16:21,080 --> 00:16:25,160
WINNOWING DOWN TO THE FINALISTS,

405
00:16:25,160 --> 00:16:26,040
IS DONE WITHOUT INFORMATION

406
00:16:26,040 --> 00:16:27,640
ABOUT WHO OR WHERE THE

407
00:16:27,640 --> 00:16:29,960
APPLICATION COMES FROM.

408
00:16:29,960 --> 00:16:34,000
SO, THE RFA REQUIRES THE

409
00:16:34,000 --> 00:16:35,440
APPLICANTS WRITE THE ABSTRACT,

410
00:16:35,440 --> 00:16:36,960
SPECIFIC AIMS AND RESEARCH PLAN,

411
00:16:36,960 --> 00:16:40,480
IN A WAY THAT MAKES IT EXTREMELY

412
00:16:40,480 --> 00:16:41,520
DIFFICULT TO IDENTIFY WHO OR

413
00:16:41,520 --> 00:16:43,920
WHERE IT COMES FROM.

414
00:16:43,920 --> 00:16:45,360
WE DO CHECK THIS.

415
00:16:45,360 --> 00:16:48,240
AND THEN IT'S ONLY AT THIS LAST

416
00:16:48,240 --> 00:16:51,240
STAGE WHEN HOPEFULLY KEY

417
00:16:51,240 --> 00:16:52,400
DECISIONS OR JUDGMENTS ABOUT THE

418
00:16:52,400 --> 00:16:54,120
IMPORTANCE AND QUALITY OF THE

419
00:16:54,120 --> 00:16:56,760
SCIENCE HAVE ALREADY BEEN MADE,

420
00:16:56,760 --> 00:16:59,120
IS THE IDENTITY REVEALED.

421
00:16:59,120 --> 00:17:01,760
SO, HOW IS THIS WORKING?

422
00:17:01,760 --> 00:17:02,880
WE'LL SEE.

423
00:17:02,880 --> 00:17:07,000
WE'RE HALFWAY INTO THIS PILOT.

424
00:17:07,000 --> 00:17:08,080
THERE'S AN EXTERNAL CONTRACTOR

425
00:17:08,080 --> 00:17:12,160
THAT'S TAKING A LOOK AT IT.

426
00:17:12,160 --> 00:17:14,920
AND WE'VE GOTTEN SOME

427
00:17:14,920 --> 00:17:15,840
INTERESTING PRELIMINARY DATA,

428
00:17:15,840 --> 00:17:17,960
BUT WE'LL -- IT'S TO BE SEEN.

429
00:17:17,960 --> 00:17:19,720
ANOTHER THING THAT WE'VE BEEN

430
00:17:19,720 --> 00:17:21,360
WORKING AT IS WE HAVE BEEN

431
00:17:21,360 --> 00:17:24,200
THINKING ABOUT WHAT YOU COULD DO

432
00:17:24,200 --> 00:17:26,480
WITH THE DEFINITION AND THE

433
00:17:26,480 --> 00:17:30,640
STRUCTURE OF THE REVIEW CRITERIA

434
00:17:30,640 --> 00:17:30,960
THEMSELVES.

435
00:17:30,960 --> 00:17:34,160
SO, A COUPLE YEARS AGO, CSR'S

436
00:17:34,160 --> 00:17:37,000
ADVISORY COUNCIL CONVENED TWO

437
00:17:37,000 --> 00:17:38,640
WORKING GROUPS, AND THEY ASKED

438
00:17:38,640 --> 00:17:41,280
THESE GROUPS TO THINK ABOUT

439
00:17:41,280 --> 00:17:42,680
SIMPLIFYING REVIEW CRITERIA WITH

440
00:17:42,680 --> 00:17:44,200
TWO GOALS.

441
00:17:44,200 --> 00:17:47,720
ONE WAS TO REDUCE THE BURDEN ON

442
00:17:47,720 --> 00:17:49,760
REVIEWERS, AND THE SECOND MORE

443
00:17:49,760 --> 00:17:52,520
IMPORTANT ONE IS TO IMPROVE THE

444
00:17:52,520 --> 00:17:55,040
QUALITY OF REVIEW.

445
00:17:55,040 --> 00:17:59,000
SO, ONE OF THESE GROUPS TOOK A

446
00:17:59,000 --> 00:18:00,000
LOOK AT GENERAL RPG REVIEW

447
00:18:00,000 --> 00:18:02,000
CRITERIA AND THE OTHER ONE

448
00:18:02,000 --> 00:18:03,720
FOCUSED ON THE CRITERIA FOR

449
00:18:03,720 --> 00:18:05,800
CLINICAL TRIALS.

450
00:18:05,800 --> 00:18:09,720
MOST OF THEM MADE THIS MAJOR

451
00:18:09,720 --> 00:18:12,040
RECOMMENDATION, WHICH WAS THAT

452
00:18:12,040 --> 00:18:14,520
WE SHOULD REORGANIZE THE CURRENT

453
00:18:14,520 --> 00:18:16,480
FIVE SCORED REVIEW CRITERIA,

454
00:18:16,480 --> 00:18:18,360
INTO THREE FACTORS.

455
00:18:18,360 --> 00:18:20,680
THE THREE FACTORS BEING THE

456
00:18:20,680 --> 00:18:22,880
IMPORTANCE OF THE SCIENCE, ITS

457
00:18:22,880 --> 00:18:24,720
FEASIBILITY AND RIGOR, THEN THE

458
00:18:24,720 --> 00:18:31,400
INVESTIGATORS AND ENVIRONMENT.

459
00:18:31,400 --> 00:18:32,960
SO, THE IDEA BEHIND ORGANIZING

460
00:18:32,960 --> 00:18:35,880
THINGS INTO THESE FACTORS IS TO

461
00:18:35,880 --> 00:18:37,080
REALLY CLEARLY FOCUS REVIEWERS'

462
00:18:37,080 --> 00:18:37,960
ATTENTION ON THE CRUCIAL

463
00:18:37,960 --> 00:18:40,040
JUDGMENTS THEY NEED TO MAKE

464
00:18:40,040 --> 00:18:41,240
ABOUT EACH APPLICATION.

465
00:18:41,240 --> 00:18:44,760
HOW IMPORTANT IS THE RESEARCH?

466
00:18:44,760 --> 00:18:47,600
HOW FEASIBLE AND RIGOROUS IS IT?

467
00:18:47,600 --> 00:18:49,040
AND SO THE OTHER THING THAT I

468
00:18:49,040 --> 00:18:52,160
WOULD POINT OUT IS THAT THIS

469
00:18:52,160 --> 00:18:56,360
STRUCTURE LENDS ITSELF TO HAVING

470
00:18:56,360 --> 00:18:57,960
THOSE CRITICAL JUDGMENTS MADE,

471
00:18:57,960 --> 00:19:00,600
WITHOUT -- AT LEAST SEPARATELY

472
00:19:00,600 --> 00:19:02,160
FROM THIS INFORMATION AND

473
00:19:02,160 --> 00:19:03,680
JUDGMENT ABOUT THE INVESTIGATORS

474
00:19:03,680 --> 00:19:04,440
AND ENVIRONMENT.

475
00:19:04,440 --> 00:19:07,600
SO IT LENDS ITSELF TO THAT SORT

476
00:19:07,600 --> 00:19:10,440
OF MULTI-STAGE PARTIALLY BLINDED

477
00:19:10,440 --> 00:19:12,000
REVIEW PROCESS THAT I JUST

478
00:19:12,000 --> 00:19:13,520
DESCRIBED TO YOU.

479
00:19:13,520 --> 00:19:15,840
SO, THAT'S SOMETHING THAT WE'LL

480
00:19:15,840 --> 00:19:21,200
BE LOOKING AT GOING FORWARD.

481
00:19:21,200 --> 00:19:22,680
ANOTHER WAY THAT WE'VE COME AT

482
00:19:22,680 --> 00:19:27,200
BIAS TRYING TO REDUCE IT IS 

483
00:19:27,200 --> 00:19:31,000
THROUGH TRAINING. 

484
00:19:31,000 --> 00:19:34,840
SO, CSR HAS LAUNCHED A BIAS

485
00:19:34,840 --> 00:19:36,000
AWARE AND MITIGATION TRAINING

486
00:19:36,000 --> 00:19:36,400
FOR REVIEWERS.

487
00:19:36,400 --> 00:19:40,200
IF YOU HAVEN'T SEEN IT, YOU

488
00:19:40,200 --> 00:19:40,600
SHOULD.

489
00:19:40,600 --> 00:19:42,360
IT'S A 30-MINUTE TRAINING.

490
00:19:42,360 --> 00:19:47,120
IT'S AIMED AT RAISING AWARENESS

491
00:19:47,120 --> 00:19:50,080
AND PROVIDING TOOLS TO MITIGATE

492
00:19:50,080 --> 00:19:51,080
BIAS.

493
00:19:51,080 --> 00:19:53,280
IT TARGETS THE MOST COMMON

494
00:19:53,280 --> 00:19:58,960
BIASES IN PEER REVIEW PROCESS,

495
00:19:58,960 --> 00:20:00,600
FOCUSING ON REVIEW, NOT GENERAL

496
00:20:00,600 --> 00:20:01,800
IMPLICIT BIAS TRAINING.

497
00:20:01,800 --> 00:20:05,000
SO FAR WE'VE INVITED OVER 15,000

498
00:20:05,000 --> 00:20:05,880
REVIEWERS TO TAKE THIS TRAINING

499
00:20:05,880 --> 00:20:09,680
SHORT LOY IN -- SHORTLY IN

500
00:20:09,680 --> 00:20:11,400
ADVANCE OF REVIEW MEETINGS, NOW

501
00:20:11,400 --> 00:20:14,960
ALMOST 11,000 HAVE DONE SO.

502
00:20:14,960 --> 00:20:18,440
THE TRAINING HAS BEEN REALLY

503
00:20:18,440 --> 00:20:19,440
WELL RECEIVED.

504
00:20:19,440 --> 00:20:21,960
WE GOT SOME NICE COMMENTS ON

505
00:20:21,960 --> 00:20:22,400
SOCIAL MEDIA.

506
00:20:22,400 --> 00:20:26,680
BUT MORE TO THE POINT, WHEN WE

507
00:20:26,680 --> 00:20:28,640
ASK -- WHEN WE SURVEYED PEOPLE

508
00:20:28,640 --> 00:20:30,040
AFTER THEY HAVE TAKEN THE

509
00:20:30,040 --> 00:20:31,720
TRAINING WE GET INDICATIONS THEY

510
00:20:31,720 --> 00:20:33,000
THINK THE TRAINING WILL MAKE A

511
00:20:33,000 --> 00:20:33,640
DIFFERENCE FOR THEM.

512
00:20:33,640 --> 00:20:36,040
SO, FOR EXAMPLE, IF YOU ASK THEM

513
00:20:36,040 --> 00:20:37,920
DID THE TRAINING -- HOW MUCH DID

514
00:20:37,920 --> 00:20:40,560
THE TRAINING HELP YOU IN

515
00:20:40,560 --> 00:20:44,400
IDENTIFYING POTENTIAL BIAS IN

516
00:20:44,400 --> 00:20:45,800
REVIEW, 90% OF RESPONDENTS SAID

517
00:20:45,800 --> 00:20:46,800
THAT IT IMPROVED THEIR ABILITY

518
00:20:46,800 --> 00:20:50,120
TO DO SO TO A MODERATE, LARGE,

519
00:20:50,120 --> 00:20:52,040
OR VERY LARGE DEGREE.

520
00:20:52,040 --> 00:20:53,600
AND SIMILARLY IF YOU ASKED THEM

521
00:20:53,600 --> 00:20:55,120
DID IT MAKE YOU, YOU KNOW, HOW

522
00:20:55,120 --> 00:20:57,200
MUCH MORE COMFORTABLE ARE YOU IN

523
00:20:57,200 --> 00:21:00,360
INTERVENING WHEN YOU SEE BIAS,

524
00:21:00,360 --> 00:21:01,800
AGAIN, 90% OF THE RESPONDENTS

525
00:21:01,800 --> 00:21:04,120
ARE SAYING THAT IT MADE THEM

526
00:21:04,120 --> 00:21:05,960
SIGNIFICANTLY MORE COMFORTABLE

527
00:21:05,960 --> 00:21:08,680
IN DOING SO.

528
00:21:08,680 --> 00:21:13,040
AND WE DO HEAR AND SEE INSTANCES

529
00:21:13,040 --> 00:21:15,560
NOW IN REVIEW COMMITTEES WHERE

530
00:21:15,560 --> 00:21:20,520
WE SEE THESE IDEAS PLAYING OUT.

531
00:21:20,520 --> 00:21:22,440
CHAIRS HAVE A REALLY IMPORTANT

532
00:21:22,440 --> 00:21:24,680
ROLE IN SETTING THE TONE AND

533
00:21:24,680 --> 00:21:26,440
CULTURE OF STUDY SECTIONS, AND

534
00:21:26,440 --> 00:21:28,840
SO WE'RE MAKING SURE THAT CHAIRS

535
00:21:28,840 --> 00:21:30,280
REALLY APPRECIATE THESE IDEAS

536
00:21:30,280 --> 00:21:35,400
AND INCORPORATE IT INTO THEIR

537
00:21:35,400 --> 00:21:36,280
PRACTICE.

538
00:21:36,280 --> 00:21:37,720
SO, EVERY SUMMER, ABOUT 90 NEW

539
00:21:37,720 --> 00:21:41,080
STUDY SECTION CHAIRS START THEIR

540
00:21:41,080 --> 00:21:41,920
TWO-YEAR TERMS.

541
00:21:41,920 --> 00:21:44,800
WE REQUIRE THAT ALL OF THEM TAKE

542
00:21:44,800 --> 00:21:49,760
PART IN A TWO-HOUR SMALL GROUP

543
00:21:49,760 --> 00:21:51,160
INTERACTIVE ORIENTATION SESSION.

544
00:21:51,160 --> 00:21:56,320
AND STARTING LAST YEAR, WE MADE

545
00:21:56,320 --> 00:21:57,120
THIS BIAS AWARENESS MITIGATION

546
00:21:57,120 --> 00:21:58,160
TRAINING PART OF IT.

547
00:21:58,160 --> 00:22:00,640
THIS YEAR WE'LL DO SO IN A

548
00:22:00,640 --> 00:22:02,320
BIGGER WAY, REALLY FOCUSING ON

549
00:22:02,320 --> 00:22:04,600
THEIR CRITICAL ROLE AS A CHAIR,

550
00:22:04,600 --> 00:22:07,400
AND THE INFLUENCE THEY HAVE IN

551
00:22:07,400 --> 00:22:12,680
SETTING AND CHANGING THE STUDY

552
00:22:12,680 --> 00:22:13,360
SECTION CULTURE.

553
00:22:13,360 --> 00:22:15,080
YEAH, I JUST WANT TO ACKNOWLEDGE

554
00:22:15,080 --> 00:22:17,920
THE WORKING GROUP THAT PUT THAT

555
00:22:17,920 --> 00:22:18,760
TRAINING TOGETHER.

556
00:22:18,760 --> 00:22:24,720
THEY DID A NICE JOB.

557
00:22:24,720 --> 00:22:24,920
OKAY.

558
00:22:24,920 --> 00:22:27,440
ANOTHER INITIATIVE IS TO MAKE IT

559
00:22:27,440 --> 00:22:29,040
EASIER FOR PEOPLE TO REPORT BIAS

560
00:22:29,040 --> 00:22:33,000
WHEN THEY SEE IT.

561
00:22:33,000 --> 00:22:35,240
CSR DOES A LOT OF REVIEW.

562
00:22:35,240 --> 00:22:37,000
WE KNOW THINGS GO WRONG AT

563
00:22:37,000 --> 00:22:37,400
TIMES.

564
00:22:37,400 --> 00:22:39,400
AND WHEN IT DOES, WE WANT TO

565
00:22:39,400 --> 00:22:42,000
KNOW ABOUT IT, AND WE REALLY

566
00:22:42,000 --> 00:22:44,520
WANT PEOPLE TO UNDERSTAND THAT

567
00:22:44,520 --> 00:22:46,720
IF THEY SEE SOMETHING, IF THEY

568
00:22:46,720 --> 00:22:48,240
SEE BIAS OR ANYTHING ELSE THAT

569
00:22:48,240 --> 00:22:49,680
COULD AFFECT THE FAIRNESS OF

570
00:22:49,680 --> 00:22:51,200
REVIEW, WE WANT TO HEAR ABOUT

571
00:22:51,200 --> 00:22:52,080
IT.

572
00:22:52,080 --> 00:22:53,760
AND SO WE'VE ESTABLISHED WHAT WE

573
00:22:53,760 --> 00:22:55,560
CALL THIS BIAS BOX.

574
00:22:55,560 --> 00:22:56,680
IT'S A BIAS REPORTING E-MAIL

575
00:22:56,680 --> 00:23:01,840
THAT GOES TO OUR ASSOCIATE 

576
00:23:01,840 --> 00:23:04,880
DIRECTOR FOR WORKFORCE

577
00:23:04,880 --> 00:23:05,640
DIVERSITY.

578
00:23:05,640 --> 00:23:07,200
AND WE'VE REALLY TAKEN EFFORTS,

579
00:23:07,200 --> 00:23:08,040
MADE MULTIPLE EFFORTS TO

580
00:23:08,040 --> 00:23:08,720
PUBLICIZE THIS.

581
00:23:08,720 --> 00:23:11,840
SO IT'S ON THE SIGNATURE LINE OF

582
00:23:11,840 --> 00:23:13,480
EVERY OUTGOING STAFF E-MAIL.

583
00:23:13,480 --> 00:23:15,680
IT'S ON THE HIGHLY TRAVELED

584
00:23:15,680 --> 00:23:20,560
PAGES OF OUR WEBSITE. 

585
00:23:20,560 --> 00:23:21,880
BUT MORE THAN THAT, AND I GUESS

586
00:23:21,880 --> 00:23:24,560
THIS IS A KEY MESSAGE HERE, THAT

587
00:23:24,560 --> 00:23:27,720
I HOPE PEOPLE BEGIN TO

588
00:23:27,720 --> 00:23:30,880
APPRECIATE THAT WHEN WE HEAR

589
00:23:30,880 --> 00:23:34,680
ABOUT BIAS OR FLAWS IN REVIEW,

590
00:23:34,680 --> 00:23:36,040
IF WE AGREE THAT SOMETHING WENT

591
00:23:36,040 --> 00:23:38,080
WRONG, WE WILL TRY TO FIX IT AND

592
00:23:38,080 --> 00:23:40,680
WE WILL FIX IT BY REREVIEWING

593
00:23:40,680 --> 00:23:42,040
THE APPLICATION WITHIN THE SAME

594
00:23:42,040 --> 00:23:42,240
REALM.

595
00:23:42,240 --> 00:23:43,880
IN OTHER WORDS, WE WILL NOT SEND

596
00:23:43,880 --> 00:23:44,680
IT FOR APPEAL.

597
00:23:44,680 --> 00:23:47,840
WE WILL TAKE IT ON OURSELVES TO

598
00:23:47,840 --> 00:23:51,680
FIX IT BY RE-REVIEWING AS

599
00:23:51,680 --> 00:23:54,400
RAPIDLY AS POSSIBLE.

600
00:23:54,400 --> 00:23:57,160
 

601
00:23:57,160 --> 00:23:59,000
SO, WE ARE OFTEN TOLD THAT WE

602
00:23:59,000 --> 00:24:01,640
OUGHT TO BE MAKING OUR STUDY

603
00:24:01,640 --> 00:24:03,960
SECTIONS MORE DIVERSE.

604
00:24:03,960 --> 00:24:05,040
AND WE AGREE.

605
00:24:05,040 --> 00:24:08,200
SO HERE'S HOW WE'RE WORKING AT

606
00:24:08,200 --> 00:24:08,640
DOING THAT.

607
00:24:08,640 --> 00:24:11,160
FIRST IN TERMS OF WORKING WITH

608
00:24:11,160 --> 00:24:13,840
OUR STAFF, WE HAVE MADE -- PUT A

609
00:24:13,840 --> 00:24:20,280
LOT OF EFFORT INTO RAISING

610
00:24:20,280 --> 00:24:21,280
COLLECTIVE AWARENESS, WANT STAFF

611
00:24:21,280 --> 00:24:22,240
TO UNDERSTAND CRITICAL

612
00:24:22,240 --> 00:24:24,200
IMPORTANCE OF DIVERSITY AND LINK

613
00:24:24,200 --> 00:24:26,040
BETWEEN DIVERSITY AND EXCELLENCE

614
00:24:26,040 --> 00:24:26,520
IN REVIEW.

615
00:24:26,520 --> 00:24:33,760
SO THIS IS A MESSAGE WE WORK AT

616
00:24:33,760 --> 00:24:35,240
HELPING PEOPLE UNDERSTAND, WE

617
00:24:35,240 --> 00:24:37,000
SET EXPECTATIONS, WE MONITOR THE

618
00:24:37,000 --> 00:24:37,200
DATA.

619
00:24:37,200 --> 00:24:40,280
YOU CAN LOOK AT THIS AS WE PUSH

620
00:24:40,280 --> 00:24:41,600
PEOPLE TO DIVERSIFY BUT YOU

621
00:24:41,600 --> 00:24:46,320
CAN'T JUST PUSH PEOPLE. 

622
00:24:46,320 --> 00:24:48,520
YOU NEED TO HELP PEOPLE FIND NEW

623
00:24:48,520 --> 00:24:51,280
REVIEWERS, AND SO WE PUT

624
00:24:51,280 --> 00:24:53,320
SIGNIFICANT EFFORT INTO BUILDING

625
00:24:53,320 --> 00:24:59,400
UP DATABASES TO BRING IN NEW

626
00:24:59,400 --> 00:25:01,560
SOURCES OF POTENTIAL REVIEWERS

627
00:25:01,560 --> 00:25:04,880
IN THIS REVIEWER FINDER, AND

628
00:25:04,880 --> 00:25:06,320
WE'VE EMPHASIZED A LOT OF

629
00:25:06,320 --> 00:25:08,360
TRAINING FOR SROs HOW YOU DO

630
00:25:08,360 --> 00:25:08,560
THIS.

631
00:25:08,560 --> 00:25:14,160
WE SHOW YOU BRIEFLY THIS TOOL 

632
00:25:14,160 --> 00:25:14,600
WE'VE DEVELOPED.

633
00:25:14,600 --> 00:25:17,120
SO, THIS IS A SEARCHABLE TOOL,

634
00:25:17,120 --> 00:25:19,200
ACCORDING TO EXPERTISE AND

635
00:25:19,200 --> 00:25:22,880
VARIOUS OTHER CHARACTERISTICS OF

636
00:25:22,880 --> 00:25:24,480
REVIEWERS THAT HELPS US FIND

637
00:25:24,480 --> 00:25:26,120
POTENTIAL REVIEWERS.

638
00:25:26,120 --> 00:25:29,080
NIH HAS A BIG DATABASE THAT HAS

639
00:25:29,080 --> 00:25:32,480
RECORDS ON EVERYBODY WHO HAS

640
00:25:32,480 --> 00:25:38,160
EVER SUBMITTED A GRANT

641
00:25:38,160 --> 00:25:39,560
APPLICATION, IT'S THIS DATABASE

642
00:25:39,560 --> 00:25:45,040
SROs GO TO TO FIND REVIEWERS.

643
00:25:45,040 --> 00:25:47,680
WE UNDERSTAND WHEN YOU LOOK AT

644
00:25:47,680 --> 00:25:50,080
AN NIH DATABASE TO REVIE GRANT

645
00:25:50,080 --> 00:25:53,960
ASP INDICATIONS, IT'S A CLOSED 

646
00:25:53,960 --> 00:25:55,320
LOOP ASPECT TO THAT.

647
00:25:55,320 --> 00:25:56,640
IF YOU WANT TO DIVERSIFY YOU

648
00:25:56,640 --> 00:25:57,960
NEED TO MAKE EFFORTS TO GET

649
00:25:57,960 --> 00:26:02,400
OUTSIDE OF THAT.

650
00:26:02,400 --> 00:26:05,960
SO WE HAVE BY BRINGING MULTIPLE

651
00:26:05,960 --> 00:26:08,840
SOURCES OF DATA, WE HAVE OUR

652
00:26:08,840 --> 00:26:12,680
EARLY CAREER REVIEWER PROGRAM,

653
00:26:12,680 --> 00:26:13,880
ASKED INSTITUTES FOR

654
00:26:13,880 --> 00:26:14,840
RECOMMENDATIONS ABOUT POTENTIAL

655
00:26:14,840 --> 00:26:16,800
REVIEWERS, WE'VE GONE TO

656
00:26:16,800 --> 00:26:17,600
PROFESSIONAL SOCIETIES AND

657
00:26:17,600 --> 00:26:20,320
MINORITY INTEREST GROUPS AND

658
00:26:20,320 --> 00:26:24,240
ASKED THEM FOR NAMES, AND THIS

659
00:26:24,240 --> 00:26:26,320
ONE IS IMPORTANT SO WE'VE ADDED

660
00:26:26,320 --> 00:26:31,480
11,000  11,000 NAMES OF PEOPLE

661
00:26:31,480 --> 00:26:35,760
FUNDED BY OTHER AGENCIES, MIGHT

662
00:26:35,760 --> 00:26:41,960
BE NSF, DoD, CDC, OR SOME 

663
00:26:41,960 --> 00:26:43,320
MAJOR PRIVATE FOUNDATIONS.

664
00:26:43,320 --> 00:26:44,960
AND SO WE'VE ADDED 24,000 NAMES

665
00:26:44,960 --> 00:26:52,600
TO THIS SORT OF CORE NIH

666
00:26:52,600 --> 00:26:57,680
DATABASE, SO DOING BROUGHT A LOT

667
00:26:57,680 --> 00:26:59,240
OF NAMES TO SRO AWARENESS.

668
00:26:59,240 --> 00:27:00,520
EFFORTS ARE MAKING A DIFFERENCE.

669
00:27:00,520 --> 00:27:02,400
IT'S NOT AN EASY TASK.

670
00:27:02,400 --> 00:27:04,160
YOU'RE LOOKING AT A GRAPH OF

671
00:27:04,160 --> 00:27:06,240
PERCENT OF WOMEN ON CSR ROSTERS

672
00:27:06,240 --> 00:27:10,200
OVER THE LAST -- THIS IS OVER 

673
00:27:10,200 --> 00:27:13,920
THE LAST THREE YEARS.

674
00:27:13,920 --> 00:27:16,720
THE GRAY LINE IS A PERCENT OF

675
00:27:16,720 --> 00:27:18,480
APPLICATIONS THAT CAME TO --

676
00:27:18,480 --> 00:27:23,040
WERE REVIEWED BY CSR IN THE MAY

677
00:27:23,040 --> 00:27:24,080
COUNCIL ROUND, SO 33%.

678
00:27:24,080 --> 00:27:26,480
GREEN LINE IS PERCENT OF WOMEN

679
00:27:26,480 --> 00:27:29,720
ON OUR STANDING PANEL ROSTERS,

680
00:27:29,720 --> 00:27:32,720
AND RED LINE IS PERCENT OF WOMEN

681
00:27:32,720 --> 00:27:38,000
ON OUR SPECIAL EMPHASIS PANELS. 

682
00:27:38,000 --> 00:27:40,400
YOU CAN SEE BOTH ARE GRADUALLY

683
00:27:40,400 --> 00:27:40,840
TRENDING UP.

684
00:27:40,840 --> 00:27:44,000
SIMILARLY, IF YOU LOOK AT THE

685
00:27:44,000 --> 00:27:46,120
PERCENT OF UNDERREPRESENTED

686
00:27:46,120 --> 00:27:49,520
MINORITIES ON OUR ROSTERS, THE

687
00:27:49,520 --> 00:27:51,280
REFERENCE POINT HERE, THIS 8.8%,

688
00:27:51,280 --> 00:27:53,080
THAT'S THE PERCENT OF

689
00:27:53,080 --> 00:27:54,360
APPLICATIONS CSR REVIEWED IN THE

690
00:27:54,360 --> 00:27:56,840
MAY COUNCIL THAT CAME FROM

691
00:27:56,840 --> 00:27:58,040
UNDERREPRESENTED MINORITIES,

692
00:27:58,040 --> 00:28:00,680
AGAIN THE GREEN LINE IS PERCENT

693
00:28:00,680 --> 00:28:02,080
ON OUR STANDING PANELS, AND RED

694
00:28:02,080 --> 00:28:07,040
LINE IS ON OUR SPECIAL EMPHASIS

695
00:28:07,040 --> 00:28:07,760
PANELS.

696
00:28:07,760 --> 00:28:11,240
SO, AGAIN, WE ARE SEEING

697
00:28:11,240 --> 00:28:16,320
PROGRESS ON THIS. 

698
00:28:16,320 --> 00:28:18,600
AND THEN FINALLY JUST TO MENTION

699
00:28:18,600 --> 00:28:21,800
ADDITIONAL EFFORT WE WERE 

700
00:28:21,800 --> 00:28:26,360
UNDERTAKING AT THIS POINT,

701
00:28:26,360 --> 00:28:28,440
EXCUSE ME, SO CSR REVIEWS OVER

702
00:28:28,440 --> 00:28:30,000
90% OF FELLOWSHIP APPLICATIONS

703
00:28:30,000 --> 00:28:31,400
THAT COME TO NIH, AND SO THE

704
00:28:31,400 --> 00:28:37,320
NEXT THING WE'RE LOOKING AT IS

705
00:28:37,320 --> 00:28:39,040
FELLOWSHIP REVIEW.

706
00:28:39,040 --> 00:28:41,800
THE ADVISORY COUNCIL CONVENED

707
00:28:41,800 --> 00:28:44,200
ANOTHER WORK GROUP CHARGING THE

708
00:28:44,200 --> 00:28:46,080
WORK GROUP WITH EXAMINING THE

709
00:28:46,080 --> 00:28:47,680
FELLOWSHIP REVIEW CRITERIA AND

710
00:28:47,680 --> 00:28:50,200
PROCESS WITH AIM TOWARD MAKING

711
00:28:50,200 --> 00:28:53,400
IT AS FAIR AND OPEN AS POSSIBLE.

712
00:28:53,400 --> 00:28:56,760
SO, THAT'S AN EFFORT UNDERWAY,

713
00:28:56,760 --> 00:28:58,240
AND WILL BE PLAYING OUT OVER THE

714
00:28:58,240 --> 00:29:02,480
NEXT YEAR OR SO.

715
00:29:02,480 --> 00:29:05,080
SO, LET ME PAUSE AT THIS POINT.

716
00:29:05,080 --> 00:29:06,840
I'LL TAKE DOWN MY SLIDES.

717
00:29:06,840 --> 00:29:09,520
I CAN COME BACK IF YOU WANT BUT

718
00:29:09,520 --> 00:29:11,560
I'LL TAKE THEM DOWN.

719
00:29:11,560 --> 00:29:14,640
AND WE CAN -- I CAN TAKE YOUR

720
00:29:14,640 --> 00:29:16,400
QUESTIONS.

721
00:29:16,400 --> 00:29:17,680
>> THANK YOU, BRUCE.

722
00:29:17,680 --> 00:29:20,440
THAT WAS SO INFORMATIVE AND

723
00:29:20,440 --> 00:29:20,720
INTERESTING.

724
00:29:20,720 --> 00:29:26,560
WE HAVE ABOUT 20 MINUTES FOR

725
00:29:26,560 --> 00:29:27,880
DISCUSSION AND EMILY BUSS,

726
00:29:27,880 --> 00:29:28,200
PLEASE.

727
00:29:28,200 --> 00:29:29,760
>> THANK YOU, VERY
INTERESTING

728
00:29:29,760 --> 00:29:30,360
AND THOUGHT PROVOKING.

729
00:29:30,360 --> 00:29:32,240
I HAVE A QUESTION ABOUT THE

730
00:29:32,240 --> 00:29:35,120
FIRST SET OF DATA THAT YOU

731
00:29:35,120 --> 00:29:35,640
SHOWED.

732
00:29:35,640 --> 00:29:39,480
I'M CURIOUS IF YOU ANALYZED IT

733
00:29:39,480 --> 00:29:43,000
BY DEMOGRAPHIC OF THE SIMULATED

734
00:29:43,000 --> 00:29:47,240
REVIEW REVIEWER, THAT IS OUR

735
00:29:47,240 --> 00:29:48,360
PEOPLE FROM UNDERRESOURCED

736
00:29:48,360 --> 00:29:50,520
INSTITUTIONS LESS LIKELY TO DING

737
00:29:50,520 --> 00:29:52,600
AN APPLICATION FROM AND

738
00:29:52,600 --> 00:29:53,720
UNDERRESOURCED APPLICATION, THAT

739
00:29:53,720 --> 00:29:56,640
KIND OF RELATIONSHIP?

740
00:29:56,640 --> 00:30:00,920
>> YEAH, NO, WE DIDN'T --
WE

741
00:30:00,920 --> 00:30:02,640
ACTUALLY DIDN'T HAVE THAT KIND

742
00:30:02,640 --> 00:30:07,360
OF INFORMATION ON THE REVIEWERS.

743
00:30:07,360 --> 00:30:13,040
SO NOT ABLE TO DO THAT.

744
00:30:13,040 --> 00:30:13,960
IT'S AN INTERESTING QUESTION

745
00:30:13,960 --> 00:30:17,560
GENERALLY BUT WE DON'T HAVE IT

746
00:30:17,560 --> 00:30:20,600
IN THAT DATASET. 

747
00:30:20,600 --> 00:30:21,840
>> THANK YOU.

748
00:30:21,840 --> 00:30:22,120
>> ARGYE?

749
00:30:22,120 --> 00:30:22,400
>> HI.

750
00:30:22,400 --> 00:30:24,880
THANK YOU SO MUCH.

751
00:30:24,880 --> 00:30:28,520
THIS IS REALLY VERY NICE AND A

752
00:30:28,520 --> 00:30:31,800
NICE EXAMPLE OF KIND OF

753
00:30:31,800 --> 00:30:33,680
INVESTIGATION INTO THE SOURCE OF

754
00:30:33,680 --> 00:30:35,080
THE BIAS, AND FINDING THE

755
00:30:35,080 --> 00:30:35,680
SOLUTION.

756
00:30:35,680 --> 00:30:37,800
I THINK THIS IS SUPER HELPFUL.

757
00:30:37,800 --> 00:30:39,880
I JUST WANTED TO COMMEND YOU AND

758
00:30:39,880 --> 00:30:41,240
THE WORKING GROUP.

759
00:30:41,240 --> 00:30:43,040
>> THANK YOU.

760
00:30:43,040 --> 00:30:46,240
THANKS A LOT.

761
00:30:46,240 --> 00:30:49,280
>> ANDY GROVES?

762
00:30:49,280 --> 00:30:50,840
>> SO, I'LL ECHO OTHER
PEOPLE.

763
00:30:50,840 --> 00:30:53,480
THANK YOU. 

764
00:30:53,480 --> 00:30:56,720
THAT WAS REALLY TERRIFIC.

765
00:30:56,720 --> 00:30:59,920
I TOOK THE TRAINING COURSE

766
00:30:59,920 --> 00:31:02,640
EARLIER THIS WEEK AT THE REQUEST

767
00:31:02,640 --> 00:31:03,760
OF BECKY WAGENAAR-MILLER.

768
00:31:03,760 --> 00:31:06,960
I FOUND IT TERRIFIC AND HELPFUL.

769
00:31:06,960 --> 00:31:09,320
AND ENTERTAINING AS WELL.

770
00:31:09,320 --> 00:31:10,080
THOUGHT PROVOKING.

771
00:31:10,080 --> 00:31:12,960
IN TERMS OF -- I WAS PLEASED TO

772
00:31:12,960 --> 00:31:15,360
SEE YOUR STATISTIC SUGGESTING

773
00:31:15,360 --> 00:31:17,200
THAT TAKING THIS TRAINING IS

774
00:31:17,200 --> 00:31:19,080
EMPOWERING PEOPLE TO SPEAK UP

775
00:31:19,080 --> 00:31:21,800
MORE, BUT AS WE'RE ALL AWARE ON

776
00:31:21,800 --> 00:31:23,760
STUDY SECTIONS SOME REVIEWERS

777
00:31:23,760 --> 00:31:26,720
ARE AD HOC REVIEWERS WHO MAY BE

778
00:31:26,720 --> 00:31:29,040
THERE FOR OTHER MEETING, OTHERS

779
00:31:29,040 --> 00:31:30,760
WILL ROTATE OFF, EVEN STUDY

780
00:31:30,760 --> 00:31:32,080
SECTION CHAIRS ONLY SERVE A

781
00:31:32,080 --> 00:31:33,400
TWO-YEAR TERM.

782
00:31:33,400 --> 00:31:35,480
I WONDERED IF YOU WILL ALSO BE

783
00:31:35,480 --> 00:31:38,520
AT LEAST TO SOME EXTENT

784
00:31:38,520 --> 00:31:42,040
EMPOWERING SROs TO BE ON THE

785
00:31:42,040 --> 00:31:43,760
LOOKOUT FOR THESE EXAMPLES OF

786
00:31:43,760 --> 00:31:45,640
BIAS, ALSO EMPOWERING THEM TO

787
00:31:45,640 --> 00:31:48,560
INTERVENE, IF NO ONE ELSE IS

788
00:31:48,560 --> 00:31:53,800
CAPTURING THIS SORT OF BEHAVIOR?

789
00:31:53,800 --> 00:31:54,960
>> YEAH, YEAH.

790
00:31:54,960 --> 00:31:58,040
NO, YES, THAT'S A REALLY

791
00:31:58,040 --> 00:31:59,240
IMPORTANT POINT.

792
00:31:59,240 --> 00:32:05,920
AND WE ACTUALLY HAVE INVESTED A

793
00:32:05,920 --> 00:32:08,520
LOT IN BOTH REALLY HELPING

794
00:32:08,520 --> 00:32:11,400
SROs THINK ABOUT THE IDEAS AND

795
00:32:11,400 --> 00:32:13,480
CONCEPTS BEHIND IT, AND ALSO

796
00:32:13,480 --> 00:32:15,200
JUST TO YOUR POINT, MAKING SURE

797
00:32:15,200 --> 00:32:17,320
THAT THEY UNDERSTAND THAT THEY

798
00:32:17,320 --> 00:32:23,640
HAVE A VERY APPROPRIATE ROLE IN

799
00:32:23,640 --> 00:32:24,640
INTERVENING THEMSELVES DIRECTLY.

800
00:32:24,640 --> 00:32:25,960
IT DOESN'T HAVE TO COME THROUGH

801
00:32:25,960 --> 00:32:27,280
JUST A CHAIR OR STUDY SECTION

802
00:32:27,280 --> 00:32:28,400
MEMBER, BUT THEY HAVE THE

803
00:32:28,400 --> 00:32:31,840
IMPORTANT ROLE AND THEY HAVE

804
00:32:31,840 --> 00:32:32,600
THE, YEAH, IT'S ABSOLUTELY

805
00:32:32,600 --> 00:32:34,640
APPROPRIATE FOR THEM TO STEP IN

806
00:32:34,640 --> 00:32:37,920
WHEN THEY SEE THAT SORT OF

807
00:32:37,920 --> 00:32:38,480
THING.

808
00:32:38,480 --> 00:32:40,000
SO, YES, YEAH, EVERYBODY IN THE

809
00:32:40,000 --> 00:32:42,720
MEETING, THE MORE PEOPLE YOU

810
00:32:42,720 --> 00:32:44,520
HAVE WORKING WITH THOSE IDEAS,

811
00:32:44,520 --> 00:32:48,880
THE BETTER.

812
00:32:48,880 --> 00:32:51,680
 

813
00:32:51,680 --> 00:32:52,960
 

814
00:32:52,960 --> 00:32:54,560
>> RUTH ANN EATOCK?

815
00:32:54,560 --> 00:32:55,600
>> THANKS FOR AN
INTERESTING

816
00:32:55,600 --> 00:32:56,480
PRESENTATION.

817
00:32:56,480 --> 00:32:58,240
I WANTED TO ASK WHAT YOUR GROUPS

818
00:32:58,240 --> 00:33:00,400
THAT ARE WORKING ON THIS THINK

819
00:33:00,400 --> 00:33:04,240
ABOUT HOW TO DEAL WITH THE

820
00:33:04,240 --> 00:33:07,520
STRONG REQUIREMENTS BY CURRENT

821
00:33:07,520 --> 00:33:08,640
STUDY SECTIONs FOR EXPERTISE,

822
00:33:08,640 --> 00:33:13,040
SO THE THING WE ALL ADVISE SORT

823
00:33:13,040 --> 00:33:16,560
OF NEW APPLICANTS TO DO IS TO

824
00:33:16,560 --> 00:33:18,320
REACH OUT FOR CONSULTING

825
00:33:18,320 --> 00:33:19,440
LETTERS, YOU KNOW, TO SHOW THEY

826
00:33:19,440 --> 00:33:23,040
HAVE TALKED TO THE RIGHT PEOPLE,

827
00:33:23,040 --> 00:33:26,200
TO SORT OF DEMONSTRATE DEEP

828
00:33:26,200 --> 00:33:28,840
EXPERTISE AND I WONDER IF IN

829
00:33:28,840 --> 00:33:30,160
EFFORTS TO REVIEWS BIAS WE'LL

830
00:33:30,160 --> 00:33:37,200
END UP WITH REVIEW PANELS THAT

831
00:33:37,200 --> 00:33:38,040
LACK THAT DEEP EXPERTISE BECAUSE

832
00:33:38,040 --> 00:33:40,680
I DON'T THINK I COULD READ A

833
00:33:40,680 --> 00:33:42,560
REVIEW ON SOMETHING -- AN

834
00:33:42,560 --> 00:33:43,560
APPLICATION ON SOMETHING FROM

835
00:33:43,560 --> 00:33:46,200
REALLY CLOSE TO MY FIELD WITHOUT

836
00:33:46,200 --> 00:33:48,440
HAVING A VERY STRONG IDEA ABOUT

837
00:33:48,440 --> 00:33:49,720
WHERE IT'S COMING FROM.

838
00:33:49,720 --> 00:33:52,960
HOW DO YOU DISCUSS THAT IN YOUR

839
00:33:52,960 --> 00:33:59,080
WORKING GROUPS?

840
00:33:59,080 --> 00:34:01,840
>> SO, EXPERTISE,
EXPERTISE IS

841
00:34:01,840 --> 00:34:03,280
THE CORE REQUIREMENT FOR ANYBODY

842
00:34:03,280 --> 00:34:04,920
TO SERVE ON A STUDY SECTION.

843
00:34:04,920 --> 00:34:07,160
THEY HAVE TO HAVE EXPERTISE

844
00:34:07,160 --> 00:34:08,960
THAT'S APPROPRIATE TO THE RANGE

845
00:34:08,960 --> 00:34:13,400
OF APPLICATIONS THAT ARE BEING 

846
00:34:13,400 --> 00:34:17,960
REVIEWED WITHIN THAT PANEL.

847
00:34:17,960 --> 00:34:21,880
I THINK -- SO THIS -- THIS CAN

848
00:34:21,880 --> 00:34:23,200
BE A VERY COMPLICATED

849
00:34:23,200 --> 00:34:24,800
DISCUSSION, BUT LET ME MAKE ONE

850
00:34:24,800 --> 00:34:27,600
OF THE POINTS I THINK IS REALLY 

851
00:34:27,600 --> 00:34:31,520
IMPORTANT ABOUT IT, THAT WHEN

852
00:34:31,520 --> 00:34:32,680
PEOPLEHINK ABOUTERTISE

853
00:34:32,680 --> 00:34:35,440
THEY SOMETIMES THINK ABOUT WHAT

854
00:34:35,440 --> 00:34:38,040
I WOULD TERM SPOT-ON EXPERTISE,

855
00:34:38,040 --> 00:34:40,920
WHICH IS EXPERTISE AT THE LEVEL

856
00:34:40,920 --> 00:34:44,320
OF -- BASICALLY PEOPLE ARE DOING

857
00:34:44,320 --> 00:34:46,160
VERY, VERY SIMILAR WORK.

858
00:34:46,160 --> 00:34:49,440
SO VERY, VERY CLOSELY ALIGNED.

859
00:34:49,440 --> 00:34:51,880
AND I ACTUALLY THINK THAT, YES,

860
00:34:51,880 --> 00:34:54,040
WE DO NEED THAT EXPERTISE BUT

861
00:34:54,040 --> 00:34:55,680
YOU NEED ANOTHER SORT OF

862
00:34:55,680 --> 00:34:56,800
PERSPECTIVE ON APPLICATIONS AS

863
00:34:56,800 --> 00:34:58,440
WELL BECAUSE THERE'S REALLY TWO

864
00:34:58,440 --> 00:34:59,640
JUDGMENTS THAT STUDY SECTIONS

865
00:34:59,640 --> 00:35:02,320
HAVE TO MAKE ABOUT EACH

866
00:35:02,320 --> 00:35:02,720
APPLICATION.

867
00:35:02,720 --> 00:35:04,360
ONE IS ITS RIGOR AND

868
00:35:04,360 --> 00:35:06,440
FEASIBILITY, AND FOR RIGOR AND

869
00:35:06,440 --> 00:35:08,520
FEASIBILITY YOU REALLY DO NEED

870
00:35:08,520 --> 00:35:12,000
PEOPLE WHO REALLY CLOSELY

871
00:35:12,000 --> 00:35:13,200
UNDERSTAND THE SCIENCES,

872
00:35:13,200 --> 00:35:15,080
METHODOLOGICAL PITFALLS AND SO

873
00:35:15,080 --> 00:35:15,960
FORTH.

874
00:35:15,960 --> 00:35:16,960
BUT THE SECOND JUDGMENT STUDY

875
00:35:16,960 --> 00:35:17,960
SECTIONS HAVE TO MAKE IS THE

876
00:35:17,960 --> 00:35:19,080
IMPORTANCE OF THE SCIENCE.

877
00:35:19,080 --> 00:35:20,560
FOR IMPORTANCE OF THE SCIENCE

878
00:35:20,560 --> 00:35:23,720
YOU NEED A RANGE OF OPINIONS, A

879
00:35:23,720 --> 00:35:27,440
RANGE OF PERSPECTIVES, YOU CAN'T

880
00:35:27,440 --> 00:35:28,960
ASK JUST THE PEOPLE WHO DO THAT

881
00:35:28,960 --> 00:35:30,320
TYPE OF RESEARCH HOW IMPORTANT

882
00:35:30,320 --> 00:35:30,720
IT IS.

883
00:35:30,720 --> 00:35:33,120
YOU KNOW WHAT THE ANSWER IS,

884
00:35:33,120 --> 00:35:33,560
ANYWAY.

885
00:35:33,560 --> 00:35:35,000
YOU NEED A RANGE OF OTHERS.

886
00:35:35,000 --> 00:35:39,600
SO YOU NEED TO GET THAT BALANCE.

887
00:35:39,600 --> 00:35:42,560
EVERYBODY NEEDS TO SIGNIFICANTLY

888
00:35:42,560 --> 00:35:43,520
UNDERSTAND THE SCIENCE, BUT, YOU

889
00:35:43,520 --> 00:35:45,480
KNOW, EXACTLY HOW CLOSE THEY

890
00:35:45,480 --> 00:35:46,920
HAVE TO BE, THERE'S A PROBLEM

891
00:35:46,920 --> 00:35:50,560
WITH GETTING JUST PEOPLE WHO ARE

892
00:35:50,560 --> 00:35:52,320
TOO CLOSE.

893
00:35:52,320 --> 00:35:55,040
BUT WE NEVER WANT TO SACRIFICE

894
00:35:55,040 --> 00:35:55,840
EXPERTISE.

895
00:35:55,840 --> 00:35:57,560
THAT'S A CORE REQUIREMENT IN

896
00:35:57,560 --> 00:35:59,240
TERMS OF WHO WE HAVE TO SERVE.

897
00:35:59,240 --> 00:36:01,280
>> THANKS A LOT.

898
00:36:01,280 --> 00:36:02,600
I WONDERED ACTUALLY IF

899
00:36:02,600 --> 00:36:04,120
THERE'S -- THERE WILL BE A NEED

900
00:36:04,120 --> 00:36:07,520
TO GO TO A MORE INTERNATIONAL

901
00:36:07,520 --> 00:36:09,360
STYLE OF APPLICATION WHICH TENDS

902
00:36:09,360 --> 00:36:13,120
TO BE MUCH LESS DEPENDENT ON

903
00:36:13,120 --> 00:36:13,960
DETAIL.

904
00:36:13,960 --> 00:36:16,840
SO THEY ARE SHORTER, MORE BIG

905
00:36:16,840 --> 00:36:17,760
PICTURE.

906
00:36:17,760 --> 00:36:20,200
BUT I LOOK FORWARD TO YOUR

907
00:36:20,200 --> 00:36:21,200
CONTINUING INVESTIGATION.

908
00:36:21,200 --> 00:36:24,720
THANKS A LOT.

909
00:36:24,720 --> 00:36:33,480
>> THANK YOU.

910
00:36:33,480 --> 00:36:34,680
>> BEN SDROWBRIDGE?

911
00:36:34,680 --> 00:36:36,120
>> YOU BROUGHT UP STEPS, I
WANT

912
00:36:36,120 --> 00:36:38,320
TO ASK ABOUT THAT.

913
00:36:38,320 --> 00:36:47,080
WE HEAR DIFFERENT RUMORS AND

914
00:36:47,080 --> 00:36:47,760
PERSPECTIVES.

915
00:36:47,760 --> 00:36:48,720
FLEXIBILITY, MAYBE STEPS

916
00:36:48,720 --> 00:36:49,560
ELIMINATED, MORE TRADITIONAL

917
00:36:49,560 --> 00:36:49,920
STUDY SECTIONS.

918
00:36:49,920 --> 00:36:51,880
DO YOU HAVE A PERSPECTIVE ON

919
00:36:51,880 --> 00:36:52,360
THAT?

920
00:36:52,360 --> 00:36:55,280
WHEN YOU LOOK AT PROBLEMS THAT

921
00:36:55,280 --> 00:36:57,360
HAPPEN THAT ARE REPORTED, IS

922
00:36:57,360 --> 00:37:07,400
THERE A  BIG DIFFERENCE BETWEEN 

923
00:37:07,400 --> 00:37:08,640
STEPS AND REGULAR PANELS?

924
00:37:08,640 --> 00:37:10,080
>> SO, LET ME START WITH
THE

925
00:37:10,080 --> 00:37:12,240
SECOND QUESTION FIRST.

926
00:37:12,240 --> 00:37:16,040
DO WE SEE MORE PROBLEMS.

927
00:37:16,040 --> 00:37:17,400
WELL, I WILL SAY YOU SAW THIS A

928
00:37:17,400 --> 00:37:21,440
LITTLE BIT IN THE DATA I SHOWED

929
00:37:21,440 --> 00:37:23,120
YOU ABOUT DIVERSITY ON

930
00:37:23,120 --> 00:37:24,760
DIFFERENT -- ON STEPS VERSUS

931
00:37:24,760 --> 00:37:26,400
STANDING PANEL.

932
00:37:26,400 --> 00:37:28,200
UNTIL RECENTLY, WE PAID LESS

933
00:37:28,200 --> 00:37:29,800
ATTENTION TO STEPS, AND SO I

934
00:37:29,800 --> 00:37:32,080
THINK WE DID SEE MORE PROBLEMS

935
00:37:32,080 --> 00:37:35,040
WITH LACK OF DIVERSITY ON THEM.

936
00:37:35,040 --> 00:37:35,960
BUT WE'RE PAYING CLOSER

937
00:37:35,960 --> 00:37:39,320
ATTENTION NOW AND I THINK THAT

938
00:37:39,320 --> 00:37:39,680
HELPS.

939
00:37:39,680 --> 00:37:42,440
BUT IN TERMS OF OTHER KINDS OF

940
00:37:42,440 --> 00:37:44,920
PROBLEMS, NO, I DON'T THINK THAT

941
00:37:44,920 --> 00:37:49,120
YOU SEE A PREDOMINANCE AMONG --

942
00:37:49,120 --> 00:37:49,960
YOU KNOW, EITHER WAY.

943
00:37:49,960 --> 00:37:52,160
AND SORT OF TO YOUR FIRST POINT,

944
00:37:52,160 --> 00:37:54,360
I DON'T SEE EITHER ONE OF THEM

945
00:37:54,360 --> 00:37:57,400
GOING AWAY.

946
00:37:57,400 --> 00:38:00,040
I MEAN, SO CSR IS REALLY DEEPLY

947
00:38:00,040 --> 00:38:03,960
INVESTED IN MAKING SURE THAT THE

948
00:38:03,960 --> 00:38:05,000
STANDING STUDY SECTIONS ARE

949
00:38:05,000 --> 00:38:06,920
ALIGNED WITH SORT OF THE

950
00:38:06,920 --> 00:38:09,560
PROGRESS OF SCIENCE, JUST TO SAY

951
00:38:09,560 --> 00:38:10,840
SCIENCE CHANGES, STUDY SECTIONS

952
00:38:10,840 --> 00:38:12,600
HAVE TO CHANGE, BUT THE

953
00:38:12,600 --> 00:38:14,040
FUNDAMENTAL STRUCTURE OF HAVING

954
00:38:14,040 --> 00:38:15,440
STANDING STUDY SECTIONS IS

955
00:38:15,440 --> 00:38:17,400
REALLY NOT IN QUESTION AT THIS

956
00:38:17,400 --> 00:38:17,720
POINT.

957
00:38:17,720 --> 00:38:19,040
BUT FOR A WHOLE VARIETY OF

958
00:38:19,040 --> 00:38:20,240
REASONS, THEY JUST CAN'T COVER

959
00:38:20,240 --> 00:38:24,760
THE WHOLE RANGE OF TOPICS.

960
00:38:24,760 --> 00:38:27,040
AND SO, YEAH, THERE'S GOING TO

961
00:38:27,040 --> 00:38:28,760
BE A ROLE FOR STEPS AS LONG AS I

962
00:38:28,760 --> 00:38:29,640
CAN SEE.

963
00:38:29,640 --> 00:38:40,040
WE EXPECT TO HAVE BOTH. 

964
00:38:41,240 --> 00:38:41,560
>> THANK THANKS.

965
00:38:41,560 --> 00:38:41,840
>> NIRUPI.

966
00:38:41,840 --> 00:38:43,680
>> YES, THANK YOU.

967
00:38:43,680 --> 00:38:45,080
SO, I'D LIKE TO -- I HAVE A

968
00:38:45,080 --> 00:38:48,360
QUESTION OF MY OWN BUT I'D LIKE

969
00:38:48,360 --> 00:38:53,840
TO ECHO RUTH ANN'S POINT SHE

970
00:38:53,840 --> 00:38:57,120
MADE, WHICH IS THAT SO IN ALL OF

971
00:38:57,120 --> 00:38:58,880
MY YEARS OF BEING CHAIRS AND

972
00:38:58,880 --> 00:39:04,360
REVIEWER AND ALL OF THAT, IT

973
00:39:04,360 --> 00:39:06,840
SEEMS LIKE SROs OFTEN DO TEND

974
00:39:06,840 --> 00:39:10,880
TO PICK PEOPLE WHO ARE VERY

975
00:39:10,880 --> 00:39:16,720
CLOSE TO THE FIELD OF A

976
00:39:16,720 --> 00:39:17,880
PARTICULAR APPLICATION.

977
00:39:17,880 --> 00:39:24,040
AND SO PERHAPS THERE'S ROOM FOR

978
00:39:24,040 --> 00:39:25,520
SOME RETRAINING THERE.

979
00:39:25,520 --> 00:39:27,120
>> YEAH, FOR INTERNAL

980
00:39:27,120 --> 00:39:30,160
DISCUSSIONS THERE CERTAINLY IS.

981
00:39:30,160 --> 00:39:30,800
>> OKAY.

982
00:39:30,800 --> 00:39:37,160
THIS IS NOT TO AT ALL SAY

983
00:39:37,160 --> 00:39:39,360
ANYTHING BAD ABOUT ANY SRO, BUT

984
00:39:39,360 --> 00:39:40,560
IT'S A NATURAL INCLINATION, YOU

985
00:39:40,560 --> 00:39:42,200
KNOW WHO HAS EXPERTISE AND IT'S

986
00:39:42,200 --> 00:39:44,840
EASIEST TO ASSIGN SOMEBODY WHO

987
00:39:44,840 --> 00:39:48,440
YOU CAN BE CONFIDENT WILL KNOW

988
00:39:48,440 --> 00:39:50,400
WHAT'S GOING ON.

989
00:39:50,400 --> 00:39:52,600
>> NONI BURNS, THE
DIRECTOR,

990
00:39:52,600 --> 00:39:54,760
TALKS ABOUT HAVING THE MENTAL

991
00:39:54,760 --> 00:39:55,320
ROLODEX.

992
00:39:55,320 --> 00:39:56,960
SO EVERYBODY IS USES THAT.

993
00:39:56,960 --> 00:39:58,080
THIS KIND OF APPLICATION, THESE

994
00:39:58,080 --> 00:39:59,040
ARE THE FOLKS.

995
00:39:59,040 --> 00:40:02,760
YOU HAVE TO GET OUTSIDE OF THAT.

996
00:40:02,760 --> 00:40:06,480
YOU HAVE TO.

997
00:40:06,480 --> 00:40:06,760
>> YEAH.

998
00:40:06,760 --> 00:40:12,840
SO MY QUESTION THAT I HAD TOO 

999
00:40:12,840 --> 00:40:14,920
WAS ABOUT THE INSTITUTES THAT

1000
00:40:14,920 --> 00:40:17,000
FUND THE PREFERRED TOPICS

1001
00:40:17,000 --> 00:40:18,320
BECAUSE OF COURSE WE -- YOU

1002
00:40:18,320 --> 00:40:20,240
KNOW, WE ALL READ THAT PAPER

1003
00:40:20,240 --> 00:40:22,920
WHEN IT CAME OUT.

1004
00:40:22,920 --> 00:40:26,200
AND SO TWO THINGS THAT STRUCK ME

1005
00:40:26,200 --> 00:40:27,160
FROM THAT.

1006
00:40:27,160 --> 00:40:30,120
ONE IS THAT PREFERRED TOPIC,

1007
00:40:30,120 --> 00:40:33,120
WHETHER IT'S THAT PEOPLE ARE

1008
00:40:33,120 --> 00:40:37,360
CHOOSING INCORRECTLY OR IN A WAY

1009
00:40:37,360 --> 00:40:41,560
THAT SETS THEM UP FOR SORT OF A

1010
00:40:41,560 --> 00:40:47,120
TIPPED BALANCE, OR ANYTHING

1011
00:40:47,120 --> 00:40:49,320
ELSE, IS IT -- SOME OF THESE ARE

1012
00:40:49,320 --> 00:40:49,920
MORE -- I MEAN PERFECTLY

1013
00:40:49,920 --> 00:40:51,280
NATURAL, YOU KNOW, SO I LOOKED

1014
00:40:51,280 --> 00:40:53,120
AT WHAT THESE INSTITUTES ARE.

1015
00:40:53,120 --> 00:40:55,560
AND SO MINORITY HEALTH

1016
00:40:55,560 --> 00:40:57,680
INSTITUTE, OBVIOUSLY IT'S GOING

1017
00:40:57,680 --> 00:41:01,480
TO BE OF PARTICULAR INTEREST.

1018
00:41:01,480 --> 00:41:04,520
HOW DONE ONE CORRECT THAT

1019
00:41:04,520 --> 00:41:05,720
PARTICULAR PROBLEM?

1020
00:41:05,720 --> 00:41:08,320
IT JUST SEEMS LIKE -- AND

1021
00:41:08,320 --> 00:41:10,080
NURSING RESEARCH, YOU KNOW.

1022
00:41:10,080 --> 00:41:11,880
AND CHILD HEALTH DEVELOPMENT.

1023
00:41:11,880 --> 00:41:15,400
SO, ALL OF THOSE ARE REALLY KIND

1024
00:41:15,400 --> 00:41:19,480
OF OBVIOUS TOPICS OF INTEREST.

1025
00:41:19,480 --> 00:41:22,960
AND SO YOU -- WHERE IS THE

1026
00:41:22,960 --> 00:41:23,840
CORRECTION FOR THAT?

1027
00:41:23,840 --> 00:41:27,120
THE OTHER THING I THOUGHT ABOUT,

1028
00:41:27,120 --> 00:41:29,480
20%, YES, THAT'S A SIGNIFICANT

1029
00:41:29,480 --> 00:41:31,080
AMOUNT OF ACCOUNTING FOR THE

1030
00:41:31,080 --> 00:41:33,800
BIAS, BUT WHERE IS THE REST OF

1031
00:41:33,800 --> 00:41:35,400
IT?

1032
00:41:35,400 --> 00:41:38,040
THERE'S A LOT MORE.

1033
00:41:38,040 --> 00:41:40,480
>> YEAH, NO, STARTING WITH
THE

1034
00:41:40,480 --> 00:41:43,880
LAST POINT, I THINK THE

1035
00:41:43,880 --> 00:41:45,800
REPUTATIONAL FACTORS, AND IT'S

1036
00:41:45,800 --> 00:41:47,240
BROADLY -- AND THESE

1037
00:41:47,240 --> 00:41:48,960
REPUTATIONAL THINGS WORK IN BOTH

1038
00:41:48,960 --> 00:41:49,880
DIRECTIONS WHICH IS TO SAY THEY

1039
00:41:49,880 --> 00:41:52,400
CAN BE POSITIVE FOR THE BIG

1040
00:41:52,400 --> 00:41:53,480
NAMES AND BIG-NAME INSTITUTIONS

1041
00:41:53,480 --> 00:41:55,120
AND COULD BE NEGATIVE FOR THE

1042
00:41:55,120 --> 00:41:58,080
LESS-KNOWN PEOPLE IN THE SMALLER

1043
00:41:58,080 --> 00:41:59,040
LESS-KNOWN INSTITUTIONS.

1044
00:41:59,040 --> 00:42:04,640
SO I THINK THAT'S PART OF IT.

1045
00:42:04,640 --> 00:42:09,120
YOU KNOW, DONNA GINTHER'S WORK

1046
00:42:09,120 --> 00:42:10,200
IS THOUGHTFUL.

1047
00:42:10,200 --> 00:42:12,640
SHE'S DONE -- YOU KNOW, THERE'S

1048
00:42:12,640 --> 00:42:15,240
SORT OF -- TO OVERSIMPLIFY,

1049
00:42:15,240 --> 00:42:16,760
SHE'S KIND OF PURSUED TWO

1050
00:42:16,760 --> 00:42:17,240
AVENUES.

1051
00:42:17,240 --> 00:42:20,360
ONE IS PIPELINE ISSUES, AND SORT

1052
00:42:20,360 --> 00:42:21,360
OF CUMULATIVE DISADVANTAGE.

1053
00:42:21,360 --> 00:42:25,880
ANOTHER ONE IS THE ROLE OF

1054
00:42:25,880 --> 00:42:28,280
CITATION, CITATION METRICS, AND

1055
00:42:28,280 --> 00:42:33,960
CONNECTION TO SOCIAL NETWORKS IN

1056
00:42:33,960 --> 00:42:34,480
SCIENCE.

1057
00:42:34,480 --> 00:42:35,960
AND SO I WOULD -- YOU KNOW, LOOK

1058
00:42:35,960 --> 00:42:36,960
AT HER 2018 PAPER.

1059
00:42:36,960 --> 00:42:39,440
IT'S A GREAT PAPER.

1060
00:42:39,440 --> 00:42:41,080
IT'S REALLY INTERESTING IN THAT

1061
00:42:41,080 --> 00:42:41,280
RESPECT.

1062
00:42:41,280 --> 00:42:44,920
SHE GETS AT SOME OF THAT STUFF.

1063
00:42:44,920 --> 00:42:47,960
AND ON THE REMEDY TO THE

1064
00:42:47,960 --> 00:42:50,360
FUNDING, YOU KNOW, THE OTHER

1065
00:42:50,360 --> 00:42:52,240
PARTS OF THE FUNDING DISPARITY,

1066
00:42:52,240 --> 00:42:53,240
THERE'S TIMES THAT I'M HAPPY TO

1067
00:42:53,240 --> 00:43:02,520
BE ABLE TO SAY I JUST DEAL WITH

1068
00:43:02,520 --> 00:43:02,760
REVIEW.

1069
00:43:02,760 --> 00:43:04,360
REALLY, IT'S A -- AS MIKE LAUER

1070
00:43:04,360 --> 00:43:05,960
SAYS THIS HAS TO DO WITH THE

1071
00:43:05,960 --> 00:43:10,680
ECOSYSTEM OF FUNDING AT THE NIH.

1072
00:43:10,680 --> 00:43:11,400
YEAH, SO --

1073
00:43:11,400 --> 00:43:13,400
>> UH-HUH.

1074
00:43:13,400 --> 00:43:16,680
THANK YOU.

1075
00:43:16,680 --> 00:43:18,120
>> VICKIE DEAL-WILLIAMS?

1076
00:43:18,120 --> 00:43:23,960
>> THANK YOU SO MUCH FOR
THE

1077
00:43:23,960 --> 00:43:24,960
PRESENTATION.

1078
00:43:24,960 --> 00:43:26,960
IT WAS REALLY IMPRESSIVE TO SEE

1079
00:43:26,960 --> 00:43:28,160
THE SYSTEMATIC APPROACH THAT

1080
00:43:28,160 --> 00:43:30,880
YOU'RE TAKING TO LOOKING AT BIAS

1081
00:43:30,880 --> 00:43:32,160
IN THE PROCESS.

1082
00:43:32,160 --> 00:43:35,600
I AM VERY GLAD THAT I HEARD YOU

1083
00:43:35,600 --> 00:43:37,240
SAY THAT YOU RECOGNIZED AND ARE

1084
00:43:37,240 --> 00:43:42,440
NOT THROWING OUT THE IMPORTANCE

1085
00:43:42,440 --> 00:43:46,600
OF THE P.I. ON THE POTENTIAL

1086
00:43:46,600 --> 00:43:48,280
SUCCESS FOR THE RESEARCH.

1087
00:43:48,280 --> 00:43:51,800
BUT COMING BACK I THINK A LITTLE

1088
00:43:51,800 --> 00:43:54,680
BIT TO RUTH ANN'S QUESTION, AND

1089
00:43:54,680 --> 00:43:58,280
I GUESS A DEFINITION OF

1090
00:43:58,280 --> 00:44:00,240
EXPERTISE, I'M WONDERING IF

1091
00:44:00,240 --> 00:44:03,520
THERE'S ANY POSSIBILITY THAT YOU

1092
00:44:03,520 --> 00:44:08,120
MIGHT BE LOOKING AT ADDING THE

1093
00:44:08,120 --> 00:44:10,200
CONSIDERATION OF VARIABLE LIKE

1094
00:44:10,200 --> 00:44:13,720
THE EXTENT TO WHICH AN

1095
00:44:13,720 --> 00:44:16,040
INDIVIDUAL P.I. MIGHT BRING

1096
00:44:16,040 --> 00:44:21,560
ALTERNATIVES TO WHAT WOULD BE 

1097
00:44:21,560 --> 00:44:23,600
DEEMED TRADITIONAL SCIENTIFIC

1098
00:44:23,600 --> 00:44:24,320
EXPERTISE.

1099
00:44:24,320 --> 00:44:26,000
LIVED EXPERIENCE, THINGS THAT

1100
00:44:26,000 --> 00:44:29,920
MIGHT CONTRIBUTE TO THE SUCCESS

1101
00:44:29,920 --> 00:44:33,120
AND FEASIBILITY OF A PROJECT.

1102
00:44:33,120 --> 00:44:34,600
I DON'T KNOW SCIENTIFICALLY HOW

1103
00:44:34,600 --> 00:44:35,760
YOU MEASURE THAT.

1104
00:44:35,760 --> 00:44:38,240
AND I KNOW IT'S A LOT MORE

1105
00:44:38,240 --> 00:44:38,600
SUBJECTIVE.

1106
00:44:38,600 --> 00:44:42,080
BUT I DO THINK THAT THERE'S

1107
00:44:42,080 --> 00:44:44,920
VALUE IN EXPLORING THOSE KINDS

1108
00:44:44,920 --> 00:44:50,320
OF VARIABLES AS POSSIBLE WAYS TO

1109
00:44:50,320 --> 00:44:52,480
DETERMINE WHAT P.I. MIGHT BRING

1110
00:44:52,480 --> 00:44:57,080
TO THE SUCCESS OF A PROJECT.

1111
00:44:57,080 --> 00:45:00,320
>> SO, THAT'S AN
INTERESTING

1112
00:45:00,320 --> 00:45:01,560
POINT.

1113
00:45:01,560 --> 00:45:06,520
THE PLACE WHERE WE'VE REALLY 

1114
00:45:06,520 --> 00:45:07,920
THOUGHT ABOUT THIS MORE,

1115
00:45:07,920 --> 00:45:09,320
HONESTLY STRUGGLING WITH THIS

1116
00:45:09,320 --> 00:45:12,720
RIGHT NOW, IS WITH THIS LAST

1117
00:45:12,720 --> 00:45:14,600
EFFORT THAT I'VE PUT UP, WHICH

1118
00:45:14,600 --> 00:45:16,440
WAS THE REVIEW OF FELLOWSHIP

1119
00:45:16,440 --> 00:45:17,640
APPLICATIONS.

1120
00:45:17,640 --> 00:45:19,640
SO WHEN YOU LOOK AT FELLOWSHIP,

1121
00:45:19,640 --> 00:45:24,720
THE PEOPLE WHO APPLY FOR

1122
00:45:24,720 --> 00:45:27,920
FELLOWSHIPS, THERE'S A -- WHEN

1123
00:45:27,920 --> 00:45:29,880
YOU THINK ABOUT WHAT QUALIFIES

1124
00:45:29,880 --> 00:45:31,520
PEOPLE, YOU KNOW, SO YOU GET

1125
00:45:31,520 --> 00:45:35,560
PEOPLE WHO SORT OF -- YOU CAN

1126
00:45:35,560 --> 00:45:37,720
SAY ARE ON THE TRADITIONAL

1127
00:45:37,720 --> 00:45:38,880
SUCCESS TRACK, RIGHT?

1128
00:45:38,880 --> 00:45:40,120
THEY WENT TO AN ELITE SCHOOL,

1129
00:45:40,120 --> 00:45:45,800
END UP IN AN ELITE LAB, SORT OF

1130
00:45:45,800 --> 00:45:47,200
ALL THESE THINGS, BUT, YOU KNOW,

1131
00:45:47,200 --> 00:45:48,840
THOSE ARE NOT THE ONLY PEOPLE

1132
00:45:48,840 --> 00:45:51,400
WHO HAVE THE POTENTIAL TO BE

1133
00:45:51,400 --> 00:45:52,040
FABULOUS SCIENTISTS.

1134
00:45:52,040 --> 00:45:55,000
YOU HAVE OTHER PEOPLE WHO HAVE

1135
00:45:55,000 --> 00:45:57,800
NOT HAD THOSE SAME ADVANTAGES

1136
00:45:57,800 --> 00:46:00,360
AND THEIR EXPERIENCE HAS BEEN

1137
00:46:00,360 --> 00:46:01,680
MORE COMPLICATED, AND IS MAYBE

1138
00:46:01,680 --> 00:46:05,280
NOT -- YOU KNOW, SO MAYBE THEY

1139
00:46:05,280 --> 00:46:09,000
SUFFER, MAYBE THEY STRUGGLE WITH

1140
00:46:09,000 --> 00:46:09,640
UNDERGRADUATE GRADES, YOU KNOW,

1141
00:46:09,640 --> 00:46:11,080
MAYBE THEY WERE THE FIRST IN THE

1142
00:46:11,080 --> 00:46:13,760
FAMILY TO EVER GO TO COLLEGE AND

1143
00:46:13,760 --> 00:46:18,400
THERE WERE A LOT OF 

1144
00:46:18,400 --> 00:46:19,040
COMPLICATIONS GETTING THROUGH.

1145
00:46:19,040 --> 00:46:21,240
AND SO I THINK PARTICULARLY IN

1146
00:46:21,240 --> 00:46:21,720
EVALUATING FELLOWSHIP

1147
00:46:21,720 --> 00:46:24,240
APPLICATIONS WE NEED TO FIND A

1148
00:46:24,240 --> 00:46:27,920
WAY TO TAKE INTO ACCOUNT THAT A

1149
00:46:27,920 --> 00:46:30,680
BROADER VIEW OF WHAT THAT PERSON

1150
00:46:30,680 --> 00:46:31,320
BRINGS.

1151
00:46:31,320 --> 00:46:34,680
AND WHAT THEIR QUALIFICATIONS

1152
00:46:34,680 --> 00:46:34,880
ARE.

1153
00:46:34,880 --> 00:46:36,840
IT'S -- YOU KNOW, AS YOU SAY

1154
00:46:36,840 --> 00:46:38,520
IT'S NOT EASY TO DEFINE.

1155
00:46:38,520 --> 00:46:40,240
BUT I THINK WE NEED TO FIND A

1156
00:46:40,240 --> 00:46:43,080
WAY TO DO BETTER SO THAT PEOPLE

1157
00:46:43,080 --> 00:46:46,040
DON'T JUST THINK ABOUT, YOU

1158
00:46:46,040 --> 00:46:51,600
KNOW, THAT MORE TRADITIONAL

1159
00:46:51,600 --> 00:46:53,240
MARKERS EXCLUSIVELY.

1160
00:46:53,240 --> 00:46:58,880
>> THANK YOU.

1161
00:46:58,880 --> 00:47:01,720
CAROL ESPY WILSON?

1162
00:47:01,720 --> 00:47:02,120
>> OKAY.

1163
00:47:02,120 --> 00:47:05,400
I JUST WANT TO THANK YOU SO MUCH

1164
00:47:05,400 --> 00:47:07,840
FOR DOING THE HARD WORK OF

1165
00:47:07,840 --> 00:47:12,200
LOOKING INTO THIS ISSUE OF BIAS

1166
00:47:12,200 --> 00:47:12,840
IN REVIEWS.

1167
00:47:12,840 --> 00:47:14,480
SOME OF IT WAS SURPRISING TO ME

1168
00:47:14,480 --> 00:47:16,440
BUT I'M GLAD TO KNOW A LOT MORE

1169
00:47:16,440 --> 00:47:17,760
ABOUT WHAT'S CAUSING SOME OF THE

1170
00:47:17,760 --> 00:47:20,080
ISSUES THAT WE'RE HAVING IN THIS

1171
00:47:20,080 --> 00:47:20,320
AREA.

1172
00:47:20,320 --> 00:47:25,440
AND I THINK THIS WHOLE ISSUE OF

1173
00:47:25,440 --> 00:47:28,400
EXPERTISE, YOU KNOW, AS NIRUPA

1174
00:47:28,400 --> 00:47:29,960
POINTED OUT AND SEVERAL HAVE

1175
00:47:29,960 --> 00:47:32,040
SAID, YOU KNOW, IT'S A REALLY

1176
00:47:32,040 --> 00:47:33,800
HARD THING TO JUDGE AND FIGURE

1177
00:47:33,800 --> 00:47:35,520
OUT HOW TO CHANGE.

1178
00:47:35,520 --> 00:47:37,400
I'VE SEEN THIS IN ACTION WHEN I

1179
00:47:37,400 --> 00:47:38,600
WAS ON STUDY SECTION MYSELF

1180
00:47:38,600 --> 00:47:41,000
WHERE WE HAD A PROPOSAL, THIS

1181
00:47:41,000 --> 00:47:43,240
PERSON HAD HAD MULTIPLE

1182
00:47:43,240 --> 00:47:44,520
PROPOSALS AND THEN THEY WERE

1183
00:47:44,520 --> 00:47:45,840
TRYING TO KEEP THAT RESEARCH

1184
00:47:45,840 --> 00:47:47,640
GOING BUT THE PROPOSAL WAS NOT

1185
00:47:47,640 --> 00:47:49,000
WELL WRITTEN, AND ON THE FACE OF

1186
00:47:49,000 --> 00:47:51,640
IT WOULD NOT HAVE GOTTEN FUNDED,

1187
00:47:51,640 --> 00:47:53,160
IF YOU JUST LOOKED AT THAT

1188
00:47:53,160 --> 00:47:55,560
PROPOSAL BUT BECAUSE OF THE

1189
00:47:55,560 --> 00:47:56,880
REPUTATION OF THE PERSON AND,

1190
00:47:56,880 --> 00:47:58,680
YOU KNOW, THE HISTORY THEY HAVE

1191
00:47:58,680 --> 00:48:00,600
HAD, IT WAS FUNDED.

1192
00:48:00,600 --> 00:48:02,160
YOU KNOW, AND EVEN THOUGH SOME

1193
00:48:02,160 --> 00:48:04,600
OF US SPOKE UP, INCLUDING

1194
00:48:04,600 --> 00:48:06,840
MYSELF, ABOUT THAT, YOU KNOW, WE

1195
00:48:06,840 --> 00:48:11,520
WERE OVERRULED IN THAT DECISION.

1196
00:48:11,520 --> 00:48:15,800
SO, IT'S A REALLY HARD ONE TO

1197
00:48:15,800 --> 00:48:16,040
COMBAT.

1198
00:48:16,040 --> 00:48:18,760
AND NIRUPA ASKED A LOT OF

1199
00:48:18,760 --> 00:48:20,280
QUESTIONS I HAD.

1200
00:48:20,280 --> 00:48:21,720
SOME OF THE AREAS THAT AFRICAN

1201
00:48:21,720 --> 00:48:24,760
AMERICANS TEND TO LOOK AT ARE

1202
00:48:24,760 --> 00:48:26,760
THINGS WHERE THERE'S BIAS IN

1203
00:48:26,760 --> 00:48:28,080
HEALTH CARE, OTHER ISSUES WE

1204
00:48:28,080 --> 00:48:29,800
PERSONALLY HAVE TO DEAL WITH SO

1205
00:48:29,800 --> 00:48:31,560
OF COURSE THOSE AREAS ARE VERY

1206
00:48:31,560 --> 00:48:33,760
IMPORTANT TO US AND I'M NOT SURE

1207
00:48:33,760 --> 00:48:35,960
HOW YOU CHANGE THE FUNDING, THE

1208
00:48:35,960 --> 00:48:38,800
AMOUNT OF MONEY THAT GOES INTO

1209
00:48:38,800 --> 00:48:40,520
THOSE FUNDING, FUNDING LEVELS,

1210
00:48:40,520 --> 00:48:41,520
BUT IT DEFINITELY SEEMS LIKE

1211
00:48:41,520 --> 00:48:45,160
SOMETHING NEEDS TO BE DONE IN

1212
00:48:45,160 --> 00:48:46,120
THAT REGARD AS WELL.

1213
00:48:46,120 --> 00:48:47,760
BUT I DO WANT TO THANK YOU FOR

1214
00:48:47,760 --> 00:48:49,800
ALL YOU'VE DONE AND I KNOW YOU

1215
00:48:49,800 --> 00:48:51,040
GUYS ARE WORKING HARD TO TRY TO

1216
00:48:51,040 --> 00:48:52,040
FIGURE THIS OUT.

1217
00:48:52,040 --> 00:48:54,480
I HOPE YOU WILL MAKE IT --

1218
00:48:54,480 --> 00:48:55,520
YOU'LL HAVE A PUBLICATION THAT

1219
00:48:55,520 --> 00:48:57,320
WILL COME OUT SOON WITH THESE

1220
00:48:57,320 --> 00:48:58,560
RESULTS BECAUSE I'M SURE THERE

1221
00:48:58,560 --> 00:49:01,760
ARE A LOT OF, YOU KNOW, PEOPLE

1222
00:49:01,760 --> 00:49:04,400
WHO APPLY TO NIH WHO MAY HAVE

1223
00:49:04,400 --> 00:49:05,840
INPUT AND MAY HELP YOU BE ABLE

1224
00:49:05,840 --> 00:49:07,520
TO SOLVE THOSE THINGS SO PEOPLE

1225
00:49:07,520 --> 00:49:09,440
SHOULD BE -- YOU KNOW, READ ON

1226
00:49:09,440 --> 00:49:12,320
WHAT YOU'VE DONE AND GIVE

1227
00:49:12,320 --> 00:49:13,080
FEEDBACK, PRESIDENT BROADER

1228
00:49:13,080 --> 00:49:13,560
COMMUNITY.

1229
00:49:13,560 --> 00:49:15,240
SO THANK YOU.

1230
00:49:15,240 --> 00:49:17,520
>> THANKS.

1231
00:49:17,520 --> 00:49:19,920
 

1232
00:49:19,920 --> 00:49:22,880
YOU KNOW, ONE OF THE THINGS

1233
00:49:22,880 --> 00:49:24,000
ABOUT REPUTATIONAL BIAS, WHEN

1234
00:49:24,000 --> 00:49:25,960
YOU POINT IT OUT, SO MANY PEOPLE

1235
00:49:25,960 --> 00:49:27,720
SERVED ON STUDY SECTIONS HAVE

1236
00:49:27,720 --> 00:49:32,760
SEEN THIS, YOU KNOW, HAVE SEEN

1237
00:49:32,760 --> 00:49:34,600
THIS IN PLACE, HAVE SEEN THIS

1238
00:49:34,600 --> 00:49:36,920
PLAY OUT, IT STRIKES HOME FOR A

1239
00:49:36,920 --> 00:49:37,920
LOT OF PEOPLE.

1240
00:49:37,920 --> 00:49:41,600
AND I THINK A LOT OF PEOPLE HAVE

1241
00:49:41,600 --> 00:49:42,400
NOT APPRECIATED THIS

1242
00:49:42,400 --> 00:49:44,360
SIGNIFICANCE AS A FORM OF BIAS,

1243
00:49:44,360 --> 00:49:47,520
AND HOW IT REALLY PLAYS OUT WITH

1244
00:49:47,520 --> 00:49:49,200
RESPECT TO SOME OF THESE

1245
00:49:49,200 --> 00:49:50,960
DIVERSITY AND EQUITY ISSUES.

1246
00:49:50,960 --> 00:49:55,240
SO, THAT'S ONE OF THE WE NEED TO

1247
00:49:55,240 --> 00:49:56,640
HIGHLIGHT AT THIS POINT.

1248
00:49:56,640 --> 00:49:57,720
>> RIGHT, RIGHT.

1249
00:49:57,720 --> 00:49:59,480
THE FACT THAT PEOPLE, EVEN IF

1250
00:49:59,480 --> 00:50:01,520
YOU REDACT, PEOPLE KIND OF KNOW

1251
00:50:01,520 --> 00:50:02,640
STILL WHO IS APPLYING BECAUSE

1252
00:50:02,640 --> 00:50:04,360
THEY KNOW EACH OTHER AND THEY

1253
00:50:04,360 --> 00:50:07,920
KNOW EACH OTHER'S RESEARCH.

1254
00:50:07,920 --> 00:50:09,760
AND SO HOW DO YOU GET AROUND

1255
00:50:09,760 --> 00:50:13,600
THAT ISSUE, I'M NOT SURE.

1256
00:50:13,600 --> 00:50:15,000
>> YEAH.

1257
00:50:15,000 --> 00:50:15,240
THANKS.

1258
00:50:15,240 --> 00:50:15,880
>> THANK YOU.

1259
00:50:15,880 --> 00:50:19,280
>> THANK YOU SO MUCH FOR A
GREAT

1260
00:50:19,280 --> 00:50:19,680
DISCUSSION.

1261
00:50:19,680 --> 00:50:22,640
BECKY IS GOING TO SPEAK NEXT.

1262
00:50:22,640 --> 00:50:25,320
YEAH, HERE WE GO.

1263
00:50:25,320 --> 00:50:26,200
THANKS, BECKY.

1264
00:50:26,200 --> 00:50:27,600
>> THANKS, BRUCE, FOR SUCH
AN

1265
00:50:27,600 --> 00:50:28,480
ENGAGING TALK.

1266
00:50:28,480 --> 00:50:29,880
I'M LOOKING FORWARD TO SEEING

1267
00:50:29,880 --> 00:50:31,240
WHERE YOU'RE GOING WITH PEER

1268
00:50:31,240 --> 00:50:33,520
REVIEW AT CSR AND WHERE THE

1269
00:50:33,520 --> 00:50:34,400
PILOTS GO.

1270
00:50:34,400 --> 00:50:37,760
I WANT TO SPEND MY TIME TODAY

1271
00:50:37,760 --> 00:50:39,000
GOING OVER BRIEF OVERVIEW OF

1272
00:50:39,000 --> 00:50:44,040
PEER REVIEW PROCESS AND 

1273
00:50:44,040 --> 00:50:45,680
TARGETED EFFORTS.

1274
00:50:45,680 --> 00:50:49,200
I WANT TO THANK THE REVIEW

1275
00:50:49,200 --> 00:50:51,720
BRANCH FOR ASSISTANCE WITH THIS

1276
00:50:51,720 --> 00:50:52,040
PRESENTATION.

1277
00:50:52,040 --> 00:50:53,480
SO, WE SPENT TIME FOCUSING ON

1278
00:50:53,480 --> 00:50:55,560
WHAT WE CAN DO WITH PEER REVIEW,

1279
00:50:55,560 --> 00:50:57,640
THE CORNERSTONE OF THE

1280
00:50:57,640 --> 00:50:59,400
EXTRAMURAL REPROGRAM AND MUST

1281
00:50:59,400 --> 00:51:00,480
ASSURE SCIENCE IS EVALUATED BY

1282
00:51:00,480 --> 00:51:03,880
EXPERTS IN THE FIELD AND AS

1283
00:51:03,880 --> 00:51:10,600
BRUCE SAID WE SHARE THE SAME 

1284
00:51:10,600 --> 00:51:11,920
OPINION EXPERTISE IS PARAMOUNT

1285
00:51:11,920 --> 00:51:12,960
CRITERIA WE'RE LOOKING FOR, FREE

1286
00:51:12,960 --> 00:51:14,880
FROM BIAS OF ANY SORT.

1287
00:51:14,880 --> 00:51:19,320
WE WANT TO WORK WITH EVERYONE,

1288
00:51:19,320 --> 00:51:20,240
STAKEHOLDERS AND PARTICIPANTS

1289
00:51:20,240 --> 00:51:21,880
ARE RESPONSIBLE FOR CORE VALUES,

1290
00:51:21,880 --> 00:51:23,600
WHAT BRUCE TALKED ABOUT ENABLING

1291
00:51:23,600 --> 00:51:25,920
PEER REVIEWERS TO SPEAK UP WHEN

1292
00:51:25,920 --> 00:51:27,680
THEY SEE BIAS, REPORT STUFF,

1293
00:51:27,680 --> 00:51:30,080
WE'RE ALL VITAL PARTNERS IN THIS

1294
00:51:30,080 --> 00:51:30,440
TOGETHER.

1295
00:51:30,440 --> 00:51:32,520
I WAS GOING TO GIVE BACKGROUND

1296
00:51:32,520 --> 00:51:35,560
ON THE REGULATIONS OF PEER

1297
00:51:35,560 --> 00:51:37,680
REVIEW BUT WE'LL CUT THAT DOWN.

1298
00:51:37,680 --> 00:51:39,880
I WANT TO EMPHASIZE PEER REVIEW

1299
00:51:39,880 --> 00:51:41,400
IS HIGHLY REGULATED AND THERE

1300
00:51:41,400 --> 00:51:44,200
ARE A COUPLE REGULATIONS THAT

1301
00:51:44,200 --> 00:51:46,080
FEED INTO THAT AND DICTATE WHAT

1302
00:51:46,080 --> 00:51:47,840
WE MUST FOLLOW AT NIH FOR PEER

1303
00:51:47,840 --> 00:51:51,240
REVIEW AND SET UP THE TWO-TIERED

1304
00:51:51,240 --> 00:51:53,120
PROCESS OF PEER REVIEW, FIRST

1305
00:51:53,120 --> 00:51:54,520
LEVEL PER REVIEW AND ADVISORY

1306
00:51:54,520 --> 00:51:54,920
COUNCIL.

1307
00:51:54,920 --> 00:51:58,440
AND THEN THERE ARE ADDITIONAL

1308
00:51:58,440 --> 00:52:00,520
REGULATIONS THAT CODIFY THE

1309
00:52:00,520 --> 00:52:01,520
REQUIREMENTS OF PEER REVIEW

1310
00:52:01,520 --> 00:52:02,520
INCLUDING AS BRUCE MENTIONED

1311
00:52:02,520 --> 00:52:04,600
EVEN THE REVIEW CRITERIA

1312
00:52:04,600 --> 00:52:04,920
THEMSELVES.

1313
00:52:04,920 --> 00:52:06,480
AND SO THERE ARE -- THEIRS ARE

1314
00:52:06,480 --> 00:52:08,000
THE PARAMETERS THAT WE'RE

1315
00:52:08,000 --> 00:52:11,200
WORKING IN FOR PEER REVIEW.

1316
00:52:11,200 --> 00:52:15,720
AND THEN I WANT  TO SAY

1317
00:52:15,720 --> 00:52:16,520
EXPERTISE IS PARAMOUNT

1318
00:52:16,520 --> 00:52:17,280
CONSIDERATION UPDATING OR

1319
00:52:17,280 --> 00:52:18,520
DEVELOPING A ROSTER.

1320
00:52:18,520 --> 00:52:22,960
FROM OUR COUNCIL WORKING GROUP 

1321
00:52:22,960 --> 00:52:23,640
ON DIVERSITY THERE WERE

1322
00:52:23,640 --> 00:52:25,840
QUESTIONS WHAT WE LOOK FOR IN

1323
00:52:25,840 --> 00:52:28,240
REVIEW, HOW ARE REVIEWERS

1324
00:52:28,240 --> 00:52:28,880
SELECTED.

1325
00:52:28,880 --> 00:52:30,000
THIS SHOWS EVERYTHING THAT

1326
00:52:30,000 --> 00:52:32,840
SCIENTIFIC REVIEW OFFICER OR SRO

1327
00:52:32,840 --> 00:52:34,440
DOES TO BALANCE EXPERTISE AND

1328
00:52:34,440 --> 00:52:35,880
DIVERSITY AND TAKE IT SERIOUSLY,

1329
00:52:35,880 --> 00:52:37,320
ONE OF THE MOST CHALLENGING

1330
00:52:37,320 --> 00:52:40,080
TASKS THEY HAVE AS AN SRO.

1331
00:52:40,080 --> 00:52:43,000
FOR OUR REVIEW PANELS AT NIDCD

1332
00:52:43,000 --> 00:52:44,760
ALL THEY ASSIGNED REVIEWERS OR

1333
00:52:44,760 --> 00:52:45,960
APPLICATIONS PROVIDE A FULL

1334
00:52:45,960 --> 00:52:48,120
CRITIQUE, IMPORTANT TO FIND

1335
00:52:48,120 --> 00:52:49,000
REVIEWERS WITH APPROPRIATE

1336
00:52:49,000 --> 00:52:50,200
SCIENTIFIC EXPERTISE BUT THAT

1337
00:52:50,200 --> 00:52:52,960
ALSO CAN SPEAK TO BREADTH OF THE

1338
00:52:52,960 --> 00:52:53,200
FIELD.

1339
00:52:53,200 --> 00:52:55,360
SROs CONSIDER THESE ITEMS WHEN

1340
00:52:55,360 --> 00:52:57,160
THEY SELECT POTENTIAL REVIEWERS

1341
00:52:57,160 --> 00:52:59,000
AND FALL IN THREE MAIN

1342
00:52:59,000 --> 00:53:01,600
CATEGORIES RECOGNIZED AUTHORITY

1343
00:53:01,600 --> 00:53:03,680
IN THE FIELD, DIVERSITY OF

1344
00:53:03,680 --> 00:53:05,320
PERSPECTIVE, AND TIMES OF

1345
00:53:05,320 --> 00:53:07,960
SCIENCE REVIEWED IN THE

1346
00:53:07,960 --> 00:53:08,360
APPLICATION.

1347
00:53:08,360 --> 00:53:11,280
AND OUR SROs USE SEVERAL

1348
00:53:11,280 --> 00:53:13,760
DATABASES TO IDENTIFY REVIEWERS,

1349
00:53:13,760 --> 00:53:14,720
PROFESSIONAL MATERIALS,

1350
00:53:14,720 --> 00:53:16,080
CONFERENCE PROGRAMS, PUBLIC

1351
00:53:16,080 --> 00:53:17,040
DIRECTORIES, UNIVERSITY

1352
00:53:17,040 --> 00:53:20,480
WEBSITES, AS WELL AS SUGGESTIONS

1353
00:53:20,480 --> 00:53:21,640
FROM COLLEAGUES AS WELL.

1354
00:53:21,640 --> 00:53:23,720
THERE'S A BALANCING JOB AS AN

1355
00:53:23,720 --> 00:53:24,480
SRO, OFTENTIMES DECISIONS HAVE

1356
00:53:24,480 --> 00:53:25,920
TO BE MADE WHICH FACTORS ARE

1357
00:53:25,920 --> 00:53:27,320
MORE IMPORTANT FOR THATP A

1358
00:53:27,320 --> 00:53:27,880
INDICATION OR MEETING.

1359
00:53:27,880 --> 00:53:29,960
I THINK SO MANY CAME UP IN THE

1360
00:53:29,960 --> 00:53:31,800
QUESTIONS WE HAD AFTER BRUCE'S

1361
00:53:31,800 --> 00:53:32,480
TALK.

1362
00:53:32,480 --> 00:53:36,000
THERE ARE OTHER RESTRICTIONS

1363
00:53:36,000 --> 00:53:41,240
THAT ALSO LIMIT ABILITY TO 

1364
00:53:41,240 --> 00:53:44,520
REVIEW IDEAL REVIEWERS, SUCH AS

1365
00:53:44,520 --> 00:53:46,280
SERVICE RESTRICTIONS, ON

1366
00:53:46,280 --> 00:53:48,280
ADVISORY COUNCIL, YOU KNOW THAT

1367
00:53:48,280 --> 00:53:50,680
YOU'RE PROHIBITED FROM SERVING

1368
00:53:50,680 --> 00:53:52,200
ON BOTH LEVELS.

1369
00:53:52,200 --> 00:53:53,320
IF YOU'RE ON ADVISORY COUNCIL

1370
00:53:53,320 --> 00:54:00,760
YOU CAN'T SERVE ON FIRST LEVEL 

1371
00:54:00,760 --> 00:54:02,040
OF PEER REVIEW AND EXPERIENCE

1372
00:54:02,040 --> 00:54:03,600
CAN LIMIT DUE TO EXCESSIVE

1373
00:54:03,600 --> 00:54:03,840
SERVICE.

1374
00:54:03,840 --> 00:54:05,280
THERE ARE CONFLICTS OF INTEREST.

1375
00:54:05,280 --> 00:54:07,800
THOSE ARE ALSO IMPORTANT FACTORS

1376
00:54:07,800 --> 00:54:09,000
WHEN RECRUITING.

1377
00:54:09,000 --> 00:54:12,600
CONFLICTS RESULT FROM

1378
00:54:12,600 --> 00:54:14,040
INSTITUTIONAL AFFILIATION,

1379
00:54:14,040 --> 00:54:15,120
COLLABORATION, PUBLICATION,

1380
00:54:15,120 --> 00:54:18,760
MENTORSHIPS, A NUMBER OF

1381
00:54:18,760 --> 00:54:22,480
DIFFERENT THINGS CAN CONTRIBUTE 

1382
00:54:22,480 --> 00:54:23,760
TO CONFLICTS, THESE PREVENT

1383
00:54:23,760 --> 00:54:25,520
REVIEWERS FROM BEING PRESENT IN

1384
00:54:25,520 --> 00:54:26,120
REVIEW.

1385
00:54:26,120 --> 00:54:28,120
A FINAL HURDLE IS VOLUNTEER

1386
00:54:28,120 --> 00:54:28,480
NATURE.

1387
00:54:28,480 --> 00:54:29,800
SO NIH DOES NOT REQUIRE

1388
00:54:29,800 --> 00:54:30,800
INVESTIGATORS TO REVIEW.

1389
00:54:30,800 --> 00:54:32,120
THERE'S NO MANDATE IF YOU GET

1390
00:54:32,120 --> 00:54:33,960
FUNDED OR A CERTAIN NUMBER OF

1391
00:54:33,960 --> 00:54:35,800
APPLICATIONS YOU HAVE TO REVIEW.

1392
00:54:35,800 --> 00:54:37,920
AND SO THIS VOLUNTEER NATURE IS

1393
00:54:37,920 --> 00:54:39,200
THE HURDLE WE'RE CONSTANTLY

1394
00:54:39,200 --> 00:54:41,800
TRYING TO JUMP OVER IN

1395
00:54:41,800 --> 00:54:42,680
RECRUITING REVIEWERS.

1396
00:54:42,680 --> 00:54:44,680
THIS IS ALL TO SAY WE CAN'T JUST

1397
00:54:44,680 --> 00:54:46,320
PICK THE THREE PEOPLE WE IDEALLY

1398
00:54:46,320 --> 00:54:48,040
WANT TO HAVE REVIEW A PARTICULAR

1399
00:54:48,040 --> 00:54:50,280
APPLICATION AND SIGN THEM UP.

1400
00:54:50,280 --> 00:54:52,960
IT'S A STRATEGIC DECISION AND

1401
00:54:52,960 --> 00:54:53,680
RECRUIT.

1402
00:54:53,680 --> 00:54:55,320
BY THE SRO.

1403
00:54:55,320 --> 00:54:58,400
LOOKING AT ACTUAL REVIEWS,

1404
00:54:58,400 --> 00:55:01,440
APPLICATIONS AT CSR OR I.C.,

1405
00:55:01,440 --> 00:55:10,120
HIGH LEVEL SUMMARY OF BREAK DOWN

1406
00:55:10,120 --> 00:55:13,280
FOR NICDC, REVIEWING FOR RFA,

1407
00:55:13,280 --> 00:55:15,680
EARLY REAR R21, CAREER,

1408
00:55:15,680 --> 00:55:16,680
TRAINING, FRIENDSHIP

1409
00:55:16,680 --> 00:55:19,200
APPLICATIONS IN HOUSE AND

1410
00:55:19,200 --> 00:55:21,160
COMPLEX GRANTS, PROGRAM

1411
00:55:21,160 --> 00:55:23,560
PROJECTS, COOPERATIVE AGREEMENTS

1412
00:55:23,560 --> 00:55:25,880
REVIEWED AT NIDCR REVIEW

1413
00:55:25,880 --> 00:55:27,080
MEETINGS, CSR REVIEWS EVERYTHING

1414
00:55:27,080 --> 00:55:27,280
ELSE.

1415
00:55:27,280 --> 00:55:37,800
THIS SHOWS 30% AT EACH ROUND, 

1416
00:55:40,160 --> 00:55:43,320
70% REVIEWED AT CSR, MAJORITY IN

1417
00:55:43,320 --> 00:55:46,240
STUDY SECTIONS, AND THIS IS

1418
00:55:46,240 --> 00:55:49,400
EXACTLY THE OPPOSITE OF NIDCD

1419
00:55:49,400 --> 00:55:51,040
MANAGED GRANT REVIEWS MAJORITY

1420
00:55:51,040 --> 00:55:53,160
DONE IN SPECIAL EMPHASIS PANELS

1421
00:55:53,160 --> 00:55:54,160
CREATED BASED ON SCIENCE

1422
00:55:54,160 --> 00:55:57,080
SUBMITTED THAT ROUND AND FUNDING

1423
00:55:57,080 --> 00:56:00,680
TRUANT ANNOUNCEMENT HAS MULTIPLE

1424
00:56:00,680 --> 00:56:03,760
RECEIPT DATES, BASED ON

1425
00:56:03,760 --> 00:56:05,960
SUBMITTED APPLICATIONS.

1426
00:56:05,960 --> 00:56:07,960
I'VE ALREADY SHOWN FACTORS IN

1427
00:56:07,960 --> 00:56:10,320
RECRUITING, WE'RE WORKING HARD

1428
00:56:10,320 --> 00:56:13,400
TO INCREASE DIVERSITY INCLUDING

1429
00:56:13,400 --> 00:56:14,400
THE SCIENTIFIC PERSPECTIVE,

1430
00:56:14,400 --> 00:56:17,560
DEMOGRAPHICS, CAREER STAGE, AND

1431
00:56:17,560 --> 00:56:21,000
REVIEWER EXPERIENCE.

1432
00:56:21,000 --> 00:56:22,280
THIS SLIDE SHOWS SUMMARY OF

1433
00:56:22,280 --> 00:56:25,120
RANGES OF WOMEN AND MINORITIES

1434
00:56:25,120 --> 00:56:33,360
SERVING AS NIDCD PER REVIEWES

1435
00:56:33,360 --> 00:56:36,360
FROM 2015 TO 2020.

1436
00:56:36,360 --> 00:56:39,760
HIGHER PERCENTAGE EVER WOMEN

1437
00:56:39,760 --> 00:56:42,920
THAN AVERAGE, EQUIVALENT WITH

1438
00:56:42,920 --> 00:56:44,800
SPECIAL EMPHASIS PANELS.

1439
00:56:44,800 --> 00:56:50,520
RANGING FROM 19 TO 29% MINORITY

1440
00:56:50,520 --> 00:56:53,600
FOR APPOINTED, 4 TO 19% FOR

1441
00:56:53,600 --> 00:56:55,840
TEMPORARY, 1*6 TO 21% SPECIAL

1442
00:56:55,840 --> 00:56:58,640
EMPHASIS PANEL MEMBERS.

1443
00:56:58,640 --> 00:56:59,840
APPOINTED MEMBERS REQUIRE

1444
00:56:59,840 --> 00:57:02,440
APPROVAL BEYOND THE INSTITUTES.

1445
00:57:02,440 --> 00:57:04,400
STANDING STUDY SECTIONS REQUIRE

1446
00:57:04,400 --> 00:57:06,360
APPROVAL BY NIH, MEMBERSHIP FOR

1447
00:57:06,360 --> 00:57:06,880
ADVISORY COUNCIL REQUIRES

1448
00:57:06,880 --> 00:57:09,400
APPROVAL AT THE LEVEL OF THE

1449
00:57:09,400 --> 00:57:10,680
DEPARTMENT OF HEALTH AND

1450
00:57:10,680 --> 00:57:11,320
HUMIDITIES SERVICES.

1451
00:57:11,320 --> 00:57:14,560
THERE ARE MULTIPLE LEVELS TO

1452
00:57:14,560 --> 00:57:16,440
ENSURE APPROPRIATE

1453
00:57:16,440 --> 00:57:20,480
REPRESENTATION IN SELECTION.

1454
00:57:20,480 --> 00:57:21,480
BRUCE INDICATED SROs KNOW WE

1455
00:57:21,480 --> 00:57:22,360
MUST DO MORE.

1456
00:57:22,360 --> 00:57:28,280
YOU HEARD YESTERDAY FROM JUDITH

1457
00:57:28,280 --> 00:57:30,800
TO BROADEN THE POOL.

1458
00:57:30,800 --> 00:57:32,960
ONGOING PEER REVIEW OUTREACH AN

1459
00:57:32,960 --> 00:57:36,040
TRAINING EFFORTS ARE FOCUSED ON

1460
00:57:36,040 --> 00:57:37,720
IDENTIFYING POTENTIAL REVIEWERS,

1461
00:57:37,720 --> 00:57:38,680
EDUCATING STAKEHOLDERS ON PEER

1462
00:57:38,680 --> 00:57:40,200
REVIEW PROCESS.

1463
00:57:40,200 --> 00:57:41,840
THAT'S EQUALLY IMPORTANT.

1464
00:57:41,840 --> 00:57:45,120
AND THESE FALL INTO FOUR

1465
00:57:45,120 --> 00:57:46,960
INTERRELATED AREAS, CONFERENCES,

1466
00:57:46,960 --> 00:57:49,720
WEBINARS, REVIEWER

1467
00:57:49,720 --> 00:57:51,240
SELF-NOMINATION AND

1468
00:57:51,240 --> 00:57:52,760
COMMUNICATION.

1469
00:57:52,760 --> 00:58:01,600
NIDCD SCIENCE COVERS A SMALL 

1470
00:58:01,600 --> 00:58:04,840
FIELD, TO RECRUIT WE'VE REACHED

1471
00:58:04,840 --> 00:58:08,240
INTO ADJACENT FIELDS FOR

1472
00:58:08,240 --> 00:58:09,480
BIOINFORMATICS RESEARCHERS AND

1473
00:58:09,480 --> 00:58:10,720
CLINICAL TRIALS, EXPANDED

1474
00:58:10,720 --> 00:58:11,600
CONSIDERATION AND RECRUITMENT OF

1475
00:58:11,600 --> 00:58:13,680
INDIVIDUALS NEW TO REVIEW AND

1476
00:58:13,680 --> 00:58:15,280
PROVIDED ADDITIONAL TRAINING AND

1477
00:58:15,280 --> 00:58:16,120
OVERSIGHT.

1478
00:58:16,120 --> 00:58:17,800
WE'VE SHARED NAMES AMONG SROs

1479
00:58:17,800 --> 00:58:20,680
OF THOSE WHO MIGHT NOT FIT ONE

1480
00:58:20,680 --> 00:58:22,000
MEETING, MIGHT BE PERFECT FOR

1481
00:58:22,000 --> 00:58:23,520
ANOTHER PANEL COMING UP.

1482
00:58:23,520 --> 00:58:26,920
AS MEMBERS KNOW WE'RE ALSO

1483
00:58:26,920 --> 00:58:27,720
PROMOTING BIAS AWARENESS

1484
00:58:27,720 --> 00:58:29,520
TRAINING CSR DEVELOPED, AND

1485
00:58:29,520 --> 00:58:32,240
WE'VE GIVEN ACCESS TO CSR MODULE

1486
00:58:32,240 --> 00:58:34,120
FOR BIAS TRAINING, HOPEFUL THIS

1487
00:58:34,120 --> 00:58:38,160
CAN BE EXPANDED TO NIDCD PEER

1488
00:58:38,160 --> 00:58:40,360
REVIEWERS AS WELL.

1489
00:58:40,360 --> 00:58:41,880
THE SROs ATTEND CONFERENCES TO

1490
00:58:41,880 --> 00:58:43,720
STAY UP TO DATE, TO IDENTIFY

1491
00:58:43,720 --> 00:58:46,280
POTENTIAL REVIEWERS IN THE

1492
00:58:46,280 --> 00:58:46,720
FIELD.

1493
00:58:46,720 --> 00:58:49,000
SROs PROVIDE GENERAL

1494
00:58:49,000 --> 00:58:49,960
INFORMATION ABOUT FUNDING

1495
00:58:49,960 --> 00:58:50,840
OPPORTUNITIES, REVIEW IN

1496
00:58:50,840 --> 00:58:51,880
CONJUNCTION WITH PROGRAM

1497
00:58:51,880 --> 00:58:52,840
OFFICERS AT MOST CONFERENCES.

1498
00:58:52,840 --> 00:58:56,760
THIS IS DONE THROUGH FORMAL

1499
00:58:56,760 --> 00:58:58,520
PRESENTATIONS, NIDCD STAFF, OR

1500
00:58:58,520 --> 00:59:04,160
INFORMAL DISCUSSIONS AT POSTER

1501
00:59:04,160 --> 00:59:05,280
SESSIONS.

1502
00:59:05,280 --> 00:59:07,040
EXAMPLE, NIDCD SRO DR. KELLY DID

1503
00:59:07,040 --> 00:59:09,440
A TALK FOR EARLY CAREER

1504
00:59:09,440 --> 00:59:10,800
INVESTIGATORS, NATIONAL BLACK

1505
00:59:10,800 --> 00:59:11,560
ASSOCIATION FOR SPEECH LANGUAGE

1506
00:59:11,560 --> 00:59:14,840
AND HEARING MEETING THIS YEAR,

1507
00:59:14,840 --> 00:59:20,240
JOINED BY PROGRAM OFFICER DR.

1508
00:59:20,240 --> 00:59:25,720
SHACKEM FOR A Q&A SESSION, 

1509
00:59:25,720 --> 00:59:27,080
COVERING EARLY CAREER R21s.

1510
00:59:27,080 --> 00:59:28,840
DR. KELLY HAS BEEN PRESENTING

1511
00:59:28,840 --> 00:59:30,560
WEBINARS FOR THE COUNCIL OF

1512
00:59:30,560 --> 00:59:32,280
ACADEMIC PROGRAMS AND

1513
00:59:32,280 --> 00:59:33,560
COMMUNICATION SCIENCES AND

1514
00:59:33,560 --> 00:59:33,880
DISORDERS.

1515
00:59:33,880 --> 00:59:36,360
SHE'S GIVEN TWO WEBINARs TO

1516
00:59:36,360 --> 00:59:39,640
DATE, TWO MORE PLANNED.

1517
00:59:39,640 --> 00:59:43,600
FIRST SHE PRESENTED ON WITH

1518
00:59:43,600 --> 00:59:49,440
TRAINING OFFICER DR. RIVERA

1519
00:59:49,440 --> 00:59:51,720
RENTAS, RECORDED WEBINAR IS

1520
00:59:51,720 --> 00:59:54,480
VIEWABLE ON THE ORGANIZATION'S

1521
00:59:54,480 --> 00:59:55,040
WEBSITE.

1522
00:59:55,040 --> 00:59:57,080
THE MOST RECENT WEBINAR A FEW

1523
00:59:57,080 --> 01:00:03,000
WEEKS AGO DR. KELLY AND A

1524
01:00:03,000 --> 01:00:04,720
PROGRAM OFFICER PRESENTED R21s

1525
01:00:04,720 --> 01:00:05,880
FOR NEW FACULTY MEMBER.

1526
01:00:05,880 --> 01:00:07,760
TWO MORE PLANNED, ONE ON GRANT

1527
01:00:07,760 --> 01:00:11,320
APPLICATION REVIEW NOT A BLACK

1528
01:00:11,320 --> 01:00:13,040
BOX IN SEPTEMBER, NIDCD FUNDING

1529
01:00:13,040 --> 01:00:14,040
OPPORTUNITIES TO ENHANCE

1530
01:00:14,040 --> 01:00:17,600
DIVERSITY IN THE RESEARCH 

1531
01:00:17,600 --> 01:00:19,560
WORKFORCE FOR JANUARY OF 2023.

1532
01:00:19,560 --> 01:00:21,720
TO SEE UPCOMING EVENTS CHECK

1533
01:00:21,720 --> 01:00:24,240
BACK ON THE NIDCD CALENDAR OF

1534
01:00:24,240 --> 01:00:28,280
EVENTS PAGE, PAST EVENTS YOU CAN

1535
01:00:28,280 --> 01:00:30,280
SEE LINKS TO PREVIOUSLY RECORDED

1536
01:00:30,280 --> 01:00:30,920
WEBINARS.

1537
01:00:30,920 --> 01:00:33,200
HERE IS AN EXAMPLE WHERE THAT

1538
01:00:33,200 --> 01:00:34,000
WOULD TAKE YOU.

1539
01:00:34,000 --> 01:00:36,720
THE REVIEW STAFF ARE ALSO

1540
01:00:36,720 --> 01:00:39,680
ENGAGED IN OUTREACH THROUGH

1541
01:00:39,680 --> 01:00:42,600
PARTICIPATION IN A FREE EVENT TO

1542
01:00:42,600 --> 01:00:44,280
ENCOURAGE YOU TO ATTEND, SROs

1543
01:00:44,280 --> 01:00:46,000
ARE AVAILABLE FOR ONE-ON-ONE

1544
01:00:46,000 --> 01:00:46,280
MEETINGS.

1545
01:00:46,280 --> 01:00:48,320
IN ADDITION, A NUMBER OF STAFF

1546
01:00:48,320 --> 01:00:50,280
ALSO PRESENTED AT THEMED

1547
01:00:50,280 --> 01:00:51,960
WORKSHOPS, SESSIONS, PEER REVIEW

1548
01:00:51,960 --> 01:00:52,440
AND TRAINING.

1549
01:00:52,440 --> 01:00:55,440
I THINK NIH IS PLANNING FOR

1550
01:00:55,440 --> 01:00:58,520
ANOTHER VIRTUAL SEMINAR IN FALL

1551
01:00:58,520 --> 01:00:59,520
OF 2020.

1552
01:00:59,520 --> 01:01:00,800
BE ON THE LOOKOUT.

1553
01:01:00,800 --> 01:01:06,280
WITH ALL EFFORTS WE STILL MIGHT

1554
01:01:06,280 --> 01:01:07,080
MISS QUALIFIED INDIVIDUALS,

1555
01:01:07,080 --> 01:01:12,520
LAUNCHING A WEB FORM TO ALLOW

1556
01:01:12,520 --> 01:01:13,320
INDIVIDUALS TO SELF-NOMINATE.

1557
01:01:13,320 --> 01:01:15,920
THERE ARE LINKS TO THE FORM IN

1558
01:01:15,920 --> 01:01:19,640
MULTIPLE PLACES ON THE NIDCD

1559
01:01:19,640 --> 01:01:20,080
WEBSITE.

1560
01:01:20,080 --> 01:01:24,000
SROs WILL REVIEW INFORMATION 

1561
01:01:24,000 --> 01:01:26,840
PROVIDED, IN TERMS OF EXPERTISE,

1562
01:01:26,840 --> 01:01:29,800
EXPERIENCE, ET CETERA.

1563
01:01:29,800 --> 01:01:33,000
AND IT DOES NOT ENSURE BUT WILL

1564
01:01:33,000 --> 01:01:35,040
LET US KNOW YOU'RE INTERESTED.

1565
01:01:35,040 --> 01:01:37,560
WE'VE BEEN WORKING HARD TO GET

1566
01:01:37,560 --> 01:01:42,040
INFORMATION OUT TO  STAKEHOLDERS

1567
01:01:42,040 --> 01:01:47,960
ABOUT WEBINARS AND NEW FORMS.

1568
01:01:47,960 --> 01:01:49,720
PEOPLE KNOW ABOUT SOCIAL MEDIA

1569
01:01:49,720 --> 01:01:51,000
AND DIRECTOR'S MESSAGE, I

1570
01:01:51,000 --> 01:01:52,560
ENCOURAGE YOU TO SHARE THIS AND

1571
01:01:52,560 --> 01:01:54,400
HELP US EXPAND OUR REACH.

1572
01:01:54,400 --> 01:01:58,360
FINALLY I WANT TO THANK THE

1573
01:01:58,360 --> 01:01:59,560
SCIENTIFIC REVIEW BRANCH FOR

1574
01:01:59,560 --> 01:02:08,440
HARD WORK AND DEDICATION

1575
01:02:08,440 --> 01:02:09,600
MANAGING GRANT APPLICATIONS.

1576
01:02:09,600 --> 01:02:10,400
TIME FOR QUESTIONS?

1577
01:02:10,400 --> 01:02:11,720
>> IN THE INTEREST OF TIME
WE

1578
01:02:11,720 --> 01:02:13,360
SHOULD GO AHEAD AND TAKE A

1579
01:02:13,360 --> 01:02:15,240
BREAK, BUT IF YOU DO HAVE A

1580
01:02:15,240 --> 01:02:17,760
QUESTION FOR BECKY PLEASE PUT IT

1581
01:02:17,760 --> 01:02:19,440
IN THE CHAT.

1582
01:02:19,440 --> 01:02:20,720
AND THANK YOU AGAIN, BRUCE.

1583
01:02:20,720 --> 01:02:23,240
THERE ARE A COUPLE QUELLS FOR

1584
01:02:23,240 --> 01:02:25,120
YOU IN THE CHAT SO IF YOU HAVE A

1585
01:02:25,120 --> 01:02:26,600
CHANCE TO ANSWER THEM, PLEASE

1586
01:02:26,600 --> 01:02:26,920
DO.

1587
01:02:26,920 --> 01:02:29,200
BUT IF YOU DON'T WE'LL E-MAIL

1588
01:02:29,200 --> 01:02:35,440
THEM TO YOU AND GET BACK TO THE

1589
01:02:35,440 --> 01:02:36,240
QUESTIONER.

1590
01:02:36,240 --> 01:02:39,400
LET'S COME BACK AT 11:15 AND

1591
01:02:39,400 --> 01:02:40,640
START WITH OUR "BRAIN"

1592
01:02:40,640 --> 01:02:40,960
PRESENTATION.

1593
01:02:40,960 --> 01:02:48,760
THANK YOU.

1594
01:02:48,760 --> 01:02:49,960
I'M DELIGHTED TO WELCOME DR.

1595
01:02:49,960 --> 01:02:52,800
JOHN NGAI TO OUR COUNCIL

1596
01:02:52,800 --> 01:02:54,680
MEETING, DIRECTOR OF THE NIH

1597
01:02:54,680 --> 01:02:57,160
BRAIN INITIATIVE WHERE HE

1598
01:02:57,160 --> 01:02:59,120
OVERSEES THE LONG-TERM STRATEGY

1599
01:02:59,120 --> 01:03:01,240
AND DAILY OPERATIONS OF THIS

1600
01:03:01,240 --> 01:03:02,440
LARGE SCALE EFFORT.

1601
01:03:02,440 --> 01:03:04,320
HE JOINS OUR COUNCIL MEETING

1602
01:03:04,320 --> 01:03:07,040
TODAY TO PRESENT AN OVERVIEW OF

1603
01:03:07,040 --> 01:03:10,640
THE BRAIN INITIATIVE AND TO

1604
01:03:10,640 --> 01:03:13,800
HIGHLIGHT SOME OF ITS

1605
01:03:13,800 --> 01:03:14,680
ACCOMPLISHMENTS.

1606
01:03:14,680 --> 01:03:16,800
AFTER THAT PRESENTATION SEVERAL

1607
01:03:16,800 --> 01:03:18,080
NIDCD PROGRAM STAFF WILL

1608
01:03:18,080 --> 01:03:21,040
HIGHLIGHT BRAIN RESEARCH AT THE

1609
01:03:21,040 --> 01:03:23,680
NIDCD AND THEN THE NIH BRAIN

1610
01:03:23,680 --> 01:03:34,120
DEPUTY DIRECTOR DR.  DR.

1611
01:03:37,800 --> 01:03:38,400
BECKEL-MITCHCUSS

1612
01:03:38,400 --> 01:03:38,640
MORE.

1613
01:03:38,640 --> 01:03:39,160
WELCOME, JOHN.

1614
01:03:39,160 --> 01:03:42,040
>> THANKS FOR HAVING US
HERE.

1615
01:03:42,040 --> 01:03:43,880
ALWAYS DELIGHTED TO SPEAK TO

1616
01:03:43,880 --> 01:03:44,640
MEMBERS OF YOUR COUNCIL AND

1617
01:03:44,640 --> 01:03:46,200
SEEING AT LEAST THE NAMES OF

1618
01:03:46,200 --> 01:03:48,240
SOME OLD FRIENDS AND SOME OTHER

1619
01:03:48,240 --> 01:03:50,120
PEOPLE THAT I OF COURSE

1620
01:03:50,120 --> 01:03:52,440
RECOGNIZE QUITE WELL.

1621
01:03:52,440 --> 01:03:54,040
I'M GOING TO SHARE MY SCREEN.

1622
01:03:54,040 --> 01:03:58,080
CAN YOU SEE MY FIRST SLIDE?

1623
01:03:58,080 --> 01:03:59,040
>> YES.

1624
01:03:59,040 --> 01:04:00,960
>> TERRIFIC.

1625
01:04:00,960 --> 01:04:01,840
OKAY, THANKS.

1626
01:04:01,840 --> 01:04:03,480
UH-OH.

1627
01:04:03,480 --> 01:04:06,880
WHAT DID I DO?

1628
01:04:06,880 --> 01:04:07,240
OH NO.

1629
01:04:07,240 --> 01:04:11,720
>> UH-OH.

1630
01:04:11,720 --> 01:04:13,720
>> LET'S TRY THIS AGAIN.

1631
01:04:13,720 --> 01:04:17,920
LET'S SEE. 

1632
01:04:17,920 --> 01:04:18,120
OKAY.

1633
01:04:18,120 --> 01:04:19,680
HOLD ON A SECOND.

1634
01:04:19,680 --> 01:04:21,080
I KICKED MYSELF OUT OF

1635
01:04:21,080 --> 01:04:21,800
PRESENTATION MODE.

1636
01:04:21,800 --> 01:04:23,840
LET'S TRY THIS AGAIN.

1637
01:04:23,840 --> 01:04:25,480
SORRY, YOU WOULD THINK I HAD

1638
01:04:25,480 --> 01:04:26,880
NEVER DONE THIS BEFORE.

1639
01:04:26,880 --> 01:04:30,640
NOW I LOST MY ZOOM WINDOW.

1640
01:04:30,640 --> 01:04:31,760
OH MY GOODNESS.

1641
01:04:31,760 --> 01:04:39,840
THIS IS NOT GOOD.

1642
01:04:39,840 --> 01:04:41,440
>> DO WE HAVE YOUR SLIDES
JOHN?

1643
01:04:41,440 --> 01:04:43,960
>> THAT'S NOT THE PROBLEM.

1644
01:04:43,960 --> 01:04:45,680
I LOST MY ZOOM WINDOW.

1645
01:04:45,680 --> 01:04:47,920
THERE IT IS.

1646
01:04:47,920 --> 01:04:48,520
OKAY, SORRY.

1647
01:04:48,520 --> 01:04:51,200
>> YEAH, THAT HAPPENS.

1648
01:04:51,200 --> 01:04:51,760
>> SORRY, SORRY.

1649
01:04:51,760 --> 01:04:53,280
I SHOULD START BY SAYING THE

1650
01:04:53,280 --> 01:04:55,400
BRAIN INITIATIVE IS A TECHNOLOGY

1651
01:04:55,400 --> 01:04:57,120
INITIATIVE, YOU WOULD NEVER KNOW

1652
01:04:57,120 --> 01:05:03,240
IT BY WHAT'S GOING ON HERE.

1653
01:05:03,240 --> 01:05:04,240
THERE WE GO.

1654
01:05:04,240 --> 01:05:05,680
I WOULD SAY THIS HAS NEVER

1655
01:05:05,680 --> 01:05:07,160
HAPPENED BEFORE BUT I WOULD NOT

1656
01:05:07,160 --> 01:05:07,680
BE TRUTHFUL.

1657
01:05:07,680 --> 01:05:10,240
HERE WE GO.

1658
01:05:10,240 --> 01:05:11,120
OKAY.

1659
01:05:11,120 --> 01:05:11,880
ARE WE BACK?

1660
01:05:11,880 --> 01:05:12,880
>> YES.

1661
01:05:12,880 --> 01:05:13,960
>> THANKS SO MUCH.

1662
01:05:13,960 --> 01:05:16,040
ANYWAY, A PLEASURE TO BE HERE.

1663
01:05:16,040 --> 01:05:19,240
I WANT TO TELL YOU ABOUT THE NIH

1664
01:05:19,240 --> 01:05:24,280
BRAIN INITIATIVE AND WHERE WE'RE

1665
01:05:24,280 --> 01:05:29,240
GOING IN THIS BRAIN 2.0 PHASE,

1666
01:05:29,240 --> 01:05:31,920
THIS REMARKABLY EXCITING

1667
01:05:31,920 --> 01:05:32,200
ENDEAVOR.

1668
01:05:32,200 --> 01:05:33,680
SO, THE MISSION OF THE BRAIN

1669
01:05:33,680 --> 01:05:35,520
INITIATIVE, OR THE BRAIN

1670
01:05:35,520 --> 01:05:37,640
RESEARCH TO ADVANCING INNOVATIVE

1671
01:05:37,640 --> 01:05:39,360
TECHNOLOGIES INITIATIVE, IS TO

1672
01:05:39,360 --> 01:05:40,200
REVOLUTIONIZE UNDERSTANDING OF

1673
01:05:40,200 --> 01:05:44,440
THE HUMAN BRAIN ACCELERATING

1674
01:05:44,440 --> 01:05:45,600
APPLICATION OF TECHNOLOGY, NO

1675
01:05:45,600 --> 01:05:46,120
SMALL ASK.

1676
01:05:46,120 --> 01:05:47,920
ANNOUNCED BY THE WHITE HOUSE IN

1677
01:05:47,920 --> 01:05:51,320
2013 WITH FIRST AWARDS IN 2014,

1678
01:05:51,320 --> 01:05:52,040
AND REPRESENTS PARTNERSHIP

1679
01:05:52,040 --> 01:05:54,480
BETWEEN FIVE U.S. FEDERAL

1680
01:05:54,480 --> 01:05:56,000
AGENCIES AND PRIVATE

1681
01:05:56,000 --> 01:05:56,760
FOUNDATIONS, ALL EFFORTS ONGOING

1682
01:05:56,760 --> 01:05:59,400
IN THE NIH HAVE BEEN GUIDED BY

1683
01:05:59,400 --> 01:06:02,480
TWO STRATEGIC PLANS, FIRST

1684
01:06:02,480 --> 01:06:03,880
PUBLISHED IN 2014, THE BRAIN

1685
01:06:03,880 --> 01:06:05,840
2025 REPORT, AND THEN REVISIT OF

1686
01:06:05,840 --> 01:06:08,480
THE STRATEGIC PLAN BY THE BRAIN

1687
01:06:08,480 --> 01:06:13,000
2.0 REPORTS ISSUED IN LATE 2019.

1688
01:06:13,000 --> 01:06:14,200
THE NIH BRAIN INITIATIVE

1689
01:06:14,200 --> 01:06:16,600
INVOLVES TEN INSTITUTES AND

1690
01:06:16,600 --> 01:06:19,120
CENTERS, OF WHICH NIDCD IS ONE.

1691
01:06:19,120 --> 01:06:20,880
AND OUR GOAL IS TO DEVELOP AND

1692
01:06:20,880 --> 01:06:25,960
APPLY TOOLS FOR UNDERSTANDING 

1693
01:06:25,960 --> 01:06:27,360
HOW NEUROCIRCUIT UNDERLIE

1694
01:06:27,360 --> 01:06:28,600
COMPLEX BEHAVIORS IN HEALTH AND

1695
01:06:28,600 --> 01:06:29,600
DISEASE.

1696
01:06:29,600 --> 01:06:30,360
WE MUST LEVERAGE EMERGING

1697
01:06:30,360 --> 01:06:32,920
TECHNOLOGIES TO ENABLE

1698
01:06:32,920 --> 01:06:33,600
DISCOVERIES ABOUT HOW NEURAL

1699
01:06:33,600 --> 01:06:36,400
CIRCUITS FUNCTION, TO USE

1700
01:06:36,400 --> 01:06:37,720
DISCOVERIES AS FOUNDATION FOR

1701
01:06:37,720 --> 01:06:39,240
NEW THERAPEUTIC STRATEGIES FOR

1702
01:06:39,240 --> 01:06:41,120
HUMAN BRAIN DISORDERS, AND VERY,

1703
01:06:41,120 --> 01:06:44,520
VERY IMPORTANTLY TO DISSEMINATE

1704
01:06:44,520 --> 01:06:47,080
AND DEMOCRATIZE TECHNOLOGIES FOR

1705
01:06:47,080 --> 01:06:49,120
DISCOVERIES AND CLINICAL

1706
01:06:49,120 --> 01:06:49,480
APPLICATIONS.

1707
01:06:49,480 --> 01:06:50,480
I MENTIONED THE STRATEGIC PLAN

1708
01:06:50,480 --> 01:06:53,880
THAT GUIDE ALL OF OUR EFFORTS.

1709
01:06:53,880 --> 01:06:56,560
THE BRAIN 2.0 REPORTS WERE

1710
01:06:56,560 --> 01:06:59,960
ISSUED IN 2019, SO THIS WAS

1711
01:06:59,960 --> 01:07:02,560
ISSUED BY WORKING GROUPS

1712
01:07:02,560 --> 01:07:05,640
COMMISSIONED BY THE NIH

1713
01:07:05,640 --> 01:07:06,960
DIRECTORS ADVISORY COUNCIL.

1714
01:07:06,960 --> 01:07:10,440
HIGHLIGHTING A FEW MAJOR

1715
01:07:10,440 --> 01:07:12,080
FINDINGS FROM THIS BRAIN 2.0

1716
01:07:12,080 --> 01:07:14,400
REPORTS, TO USE THIS TO FRAME

1717
01:07:14,400 --> 01:07:15,880
WHAT WE'RE DOING MOVING FORWARD.

1718
01:07:15,880 --> 01:07:19,960
SO THE FIRST RECOMMENDATION WAS 

1719
01:07:19,960 --> 01:07:24,320
TO KEEP ON WHAT'S WORKINGEL

1720
01:07:24,320 --> 01:07:26,400
WITH, SUPPORT DEVELOPE FOR

1721
01:07:26,400 --> 01:07:29,160
TARGETING EVER MORE PRECISE

1722
01:07:29,160 --> 01:07:31,000
STUDIES OF NEURAL CIRCUIT

1723
01:07:31,000 --> 01:07:31,760
COMPONENTS, BALANCE INDIVIDUAL

1724
01:07:31,760 --> 01:07:36,600
INVESTIGATOR RESEARCH WITH TEAM

1725
01:07:36,600 --> 01:07:39,200
SCIENCE, LEVELS ARE VITAL.

1726
01:07:39,200 --> 01:07:42,080
WE NEED GREAT QUESTIONS, BETTER

1727
01:07:42,080 --> 01:07:44,920
TECHNOLOGIES WITH WHICH TO ASK.

1728
01:07:44,920 --> 01:07:47,440
AND THIRD TO DEVOTE AMPLE

1729
01:07:47,440 --> 01:07:49,000
RESOURCES TO LARGE SCALE

1730
01:07:49,000 --> 01:07:49,760
TRANSFORMATIVE PROJECTS, THE

1731
01:07:49,760 --> 01:07:53,680
IDEA WAS BRAIN HAD COME A LONG

1732
01:07:53,680 --> 01:07:57,840
WAY, OUR FIELDS ADVANCED

1733
01:07:57,840 --> 01:07:59,120
INCLUDING PHYSICS, COMPUTER

1734
01:07:59,120 --> 01:07:59,680
SCIENCE, ENGINEERING, THE

1735
01:07:59,680 --> 01:08:00,920
WORKING GROUP FELT THIS WAS A

1736
01:08:00,920 --> 01:08:02,520
GREAT TIME TO TAKE STOCK OF

1737
01:08:02,520 --> 01:08:04,840
WHERE WE ARE AND TO REALLY PUT

1738
01:08:04,840 --> 01:08:06,360
IN RESOURCES THAT COULD TRULY

1739
01:08:06,360 --> 01:08:09,960
TRANSFORM HOW WE DO NEUROSCIENCE

1740
01:08:09,960 --> 01:08:10,240
RESEARCH.

1741
01:08:10,240 --> 01:08:11,440
ULTIMATELY TREATMENT OF HUMAN

1742
01:08:11,440 --> 01:08:11,760
DISEASE.

1743
01:08:11,760 --> 01:08:13,400
FINALLY TO UP HANS INTEGRATION

1744
01:08:13,400 --> 01:08:17,800
OF WHAT WE DO AT THE BENCH AND

1745
01:08:17,800 --> 01:08:19,080
CLINIC WITH NEUROETHICS TO

1746
01:08:19,080 --> 01:08:21,920
SUPPORT WORK THAT CONSIDERS

1747
01:08:21,920 --> 01:08:22,840
BROADER ETHICAL, LEGAL, SOCIETAL

1748
01:08:22,840 --> 01:08:24,800
IMPLICATIONS OF WHAT WE DO.

1749
01:08:24,800 --> 01:08:25,080
OKAY.

1750
01:08:25,080 --> 01:08:28,680
SO LET ME FRAME THIS AS WELL IN

1751
01:08:28,680 --> 01:08:32,760
THE CONTEXT OF THE BRAIN BUDGET.

1752
01:08:32,760 --> 01:08:38,360
AS I MENTIONED, THE NIH BRAIN

1753
01:08:38,360 --> 01:08:40,320
INITIATIVE INVOLVES THE

1754
01:08:40,320 --> 01:08:41,760
CONTRIBUTIONS AND ACTIVITIES

1755
01:08:41,760 --> 01:08:44,680
FROM TEN NIH I.C.s, STARTED

1756
01:08:44,680 --> 01:08:47,760
WITH A FAIRLY MODEST INVESTMENT

1757
01:08:47,760 --> 01:08:49,280
IN 2014 OF ABOUT $46 MILLION OF

1758
01:08:49,280 --> 01:08:50,040
NIH MONEY.

1759
01:08:50,040 --> 01:08:52,040
SO THERE ARE TWO SOURCES OF

1760
01:08:52,040 --> 01:08:53,760
FUNDING TO THE NIH BRAIN

1761
01:08:53,760 --> 01:08:54,080
INITIATIVE.

1762
01:08:54,080 --> 01:08:56,920
ONE IS THE SO-CALLED BASE

1763
01:08:56,920 --> 01:08:58,360
FUNDING, THESE ARE ALLOCATIONS

1764
01:08:58,360 --> 01:08:59,800
MADE IN THE ANNUAL

1765
01:08:59,800 --> 01:09:01,520
APPROPRIATIONS TO EACH OF THE

1766
01:09:01,520 --> 01:09:05,120
TEN I.C.s, THAT ADDS UP THIS

1767
01:09:05,120 --> 01:09:07,120
YEAR TO $468 MILLION, WE

1768
01:09:07,120 --> 01:09:08,720
RECEIVED $8 MILLION INCREASE IN

1769
01:09:08,720 --> 01:09:11,160
THE CURRENT FISCAL YEAR SINCE

1770
01:09:11,160 --> 01:09:12,960
2021, $100 MILLION INCREASE FROM

1771
01:09:12,960 --> 01:09:14,040
2020 TO 2021.

1772
01:09:14,040 --> 01:09:16,560
NOW, IN ADDITION TO THIS BASE

1773
01:09:16,560 --> 01:09:18,640
FUNDING, WE ALSO RECEIVED FUNDS

1774
01:09:18,640 --> 01:09:20,040
FROM THE 21ST CENTURY CURES ACT,

1775
01:09:20,040 --> 01:09:25,640
WHICH  ALSO SUPPORTS CANCER

1776
01:09:25,640 --> 01:09:26,240
MOONSHOT AND PRECISION MEDICINE

1777
01:09:26,240 --> 01:09:28,240
"ALL OF US" PROGRAM.

1778
01:09:28,240 --> 01:09:30,880
FOR REASONS I'M NOT CLEAR ON

1779
01:09:30,880 --> 01:09:32,000
CONTRIBUTIONS OR AUTHORIZATIONS

1780
01:09:32,000 --> 01:09:33,680
BY THE CURES ACT VARY FROM YEAR

1781
01:09:33,680 --> 01:09:38,400
TO YEAR, SO IN THE LAST -- THIS

1782
01:09:38,400 --> 01:09:41,520
YEAR IT'S $152 MILLION, LOWER

1783
01:09:41,520 --> 01:09:43,440
LAST FISCAL YEAR AT $100 MILLION

1784
01:09:43,440 --> 01:09:46,760
BUT YOU'LL NOTE THIS HUMONGOUS

1785
01:09:46,760 --> 01:09:57,280
BUMP IN CURES, BRINGING YOU THE

1786
01:09:59,560 --> 01:10:02,040
NORTH OF $950 MILLION.

1787
01:10:02,040 --> 01:10:04,680
IN 2022 FUNDING LEVEL OF $620

1788
01:10:04,680 --> 01:10:11,360
MILLION, QUITE FOCUSED ON HOW TO

1789
01:10:11,360 --> 01:10:14,440
INVEST FUNDS AND USE ANTICIPATED

1790
01:10:14,440 --> 01:10:15,880
INCREASE IN 2023 TO LEVERAGE

1791
01:10:15,880 --> 01:10:18,160
TECHNOLOGIES AND PUSH THE FIELD

1792
01:10:18,160 --> 01:10:18,360
FORWARD.

1793
01:10:18,360 --> 01:10:20,760
WE'VE BEEN EYEING THIS LARGE

1794
01:10:20,760 --> 01:10:22,640
INCREASE IN FUNDING AT 2023 TO

1795
01:10:22,640 --> 01:10:26,360
LAUNCH THESE LARGE PROJECTS AS

1796
01:10:26,360 --> 01:10:27,680
INSPIRED BY THE BRAIN 2.0

1797
01:10:27,680 --> 01:10:27,920
REPORTS.

1798
01:10:27,920 --> 01:10:30,640
SO, THIS IS WHAT I'LL SPEND MY

1799
01:10:30,640 --> 01:10:33,920
TIME TALKING ABOUT TODAY.

1800
01:10:33,920 --> 01:10:35,080
SO, THE SIMPLE SHORT DESCRIPTION

1801
01:10:35,080 --> 01:10:37,840
OF WHAT WE'RE DOING IS THAT WE

1802
01:10:37,840 --> 01:10:39,480
NEED A PUNCH LIST AND WIRING

1803
01:10:39,480 --> 01:10:42,080
DIAGRAM OF THE BRAIN, A WAY TO

1804
01:10:42,080 --> 01:10:43,520
INTERROGATE AND MODULATE BRAIN

1805
01:10:43,520 --> 01:10:44,840
CIRCUITS IN ORDER TO UNDERSTAND

1806
01:10:44,840 --> 01:10:45,840
HOW THE BRAIN ULTIMATELY WORKS

1807
01:10:45,840 --> 01:10:49,880
AND HOW TO FIX IT WHEN IT

1808
01:10:49,880 --> 01:10:50,400
DOESN'T.

1809
01:10:50,400 --> 01:10:52,280
THE PARTS LIST, A CATALOG ON

1810
01:10:52,280 --> 01:10:56,360
ATLAS OR CENSUS OF CELL TYPES IN

1811
01:10:56,360 --> 01:10:57,760
THE BRAIN, UNDERSTANDING THEIR

1812
01:10:57,760 --> 01:10:58,680
PROPERTIES PROVIDES TOGETHER

1813
01:10:58,680 --> 01:11:00,680
WITH WIRING DIAGRAM OF THE

1814
01:11:00,680 --> 01:11:01,800
CONNECTOMIC PROPERTIES PROVIDES

1815
01:11:01,800 --> 01:11:03,080
A GROUND TRUTH INFORMATION ABOUT

1816
01:11:03,080 --> 01:11:04,520
WHAT THE CIRCUITS OF THE BRAIN

1817
01:11:04,520 --> 01:11:05,760
LOOK LIKE AND THEN WE FURTHER

1818
01:11:05,760 --> 01:11:10,120
NEED A WAY TO TEST HYPOTHESES

1819
01:11:10,120 --> 01:11:11,440
ABOUT HOW THESE CIRCUITS

1820
01:11:11,440 --> 01:11:13,640
FUNCTION AND SO THE BIG

1821
01:11:13,640 --> 01:11:14,920
CHALLENGE HERE FOR LOOKING AT

1822
01:11:14,920 --> 01:11:16,800
THE HUMAN BRAIN IS, ONE, HOW

1823
01:11:16,800 --> 01:11:18,360
DOES IT FUNCTION NORMALLY AND

1824
01:11:18,360 --> 01:11:21,320
WHAT GOES WRONG IN VARIOUS HUMAN

1825
01:11:21,320 --> 01:11:22,320
BRAIN DISORDERS.

1826
01:11:22,320 --> 01:11:24,800
THE HUGE CHALLENGE IS THE HUMAN

1827
01:11:24,800 --> 01:11:29,400
BRAIN COMPRISES ON THE ORDER OF

1828
01:11:29,400 --> 01:11:30,960
86 BILLION NEURONS, EQUIVALENT

1829
01:11:30,960 --> 01:11:35,120
NUMBER OF NON-NEURONAL CELLS 

1830
01:11:35,120 --> 01:11:36,000
INCLUDING THOSE IN INFLAMMATORY

1831
01:11:36,000 --> 01:11:38,440
RESPONSES IN CONDITIONS SUCH AS

1832
01:11:38,440 --> 01:11:39,600
LONG COVID AND NEURODEGENERATIVE

1833
01:11:39,600 --> 01:11:42,840
DISEASES, AND HOW DO WE ACTUALLY

1834
01:11:42,840 --> 01:11:45,000
GENERATE TOOLS TO ATTACK SUCH A

1835
01:11:45,000 --> 01:11:45,520
LARGE PROBLEM.

1836
01:11:45,520 --> 01:11:50,080
SO, THIS IS THE BASIS OF THE

1837
01:11:50,080 --> 01:11:52,000
BRAIN 2.0 TRANSFORMATIVE

1838
01:11:52,000 --> 01:11:53,640
PROJECTS, AGAIN INSPIRED BY THE

1839
01:11:53,640 --> 01:11:56,800
BRAIN 2.0 WORKING GROUP REPORTS

1840
01:11:56,800 --> 01:11:59,760
WITH THE GOAL TO CHANGE THE

1841
01:11:59,760 --> 01:12:00,960
TRAJECTORY OF NEUROSCIENCE

1842
01:12:00,960 --> 01:12:01,800
RESEARCH, PROVIDING NEW TOOLS

1843
01:12:01,800 --> 01:12:03,480
AND RESOURCES THAT CAN BE USED

1844
01:12:03,480 --> 01:12:04,760
TO STUDY NEURAL CIRCUITS AIR

1845
01:12:04,760 --> 01:12:07,080
CROSS THE BRAIN AND DO SO AT

1846
01:12:07,080 --> 01:12:09,280
DEPTH AND SCALE.

1847
01:12:09,280 --> 01:12:11,240
SO, THESE THREE PROJECTS ARE IN

1848
01:12:11,240 --> 01:12:13,080
ORDER FROM THE TOP A

1849
01:12:13,080 --> 01:12:15,080
COMPREHENSIVE BRAIN CELL ATLAS

1850
01:12:15,080 --> 01:12:16,200
SHIFTING EMPHASIS FROM MOUSE AND

1851
01:12:16,200 --> 01:12:18,480
I'LL TELL YOU ABOUT THAT IN A

1852
01:12:18,480 --> 01:12:20,040
MOMENT TO CREATING COMPREHENSIVE

1853
01:12:20,040 --> 01:12:21,000
PARTS LIST OF HUMAN -- CELL

1854
01:12:21,000 --> 01:12:25,120
TYPES IN THE HUMAN AND NON-HUMAN

1855
01:12:25,120 --> 01:12:26,120
PRIMATE BRAIN.

1856
01:12:26,120 --> 01:12:30,120
NEXT IS THE WHOLE BRAIN

1857
01:12:30,120 --> 01:12:31,760
MICROCONNECTIVITY PROJECT, TO

1858
01:12:31,760 --> 01:12:33,080
DEVELOP TOOLS NECESSARY TO

1859
01:12:33,080 --> 01:12:35,480
GENERATE WIRING DIAGRAM OF

1860
01:12:35,480 --> 01:12:37,320
MAMMALIAN BRAINS, AND FRANKLY WE

1861
01:12:37,320 --> 01:12:40,080
FEEL WE DO HAVE TECHNOLOGIES

1862
01:12:40,080 --> 01:12:43,880
AVAILABLE OR DEVELOPING, WE CAN

1863
01:12:43,880 --> 01:12:46,440
CATALOG IN THE HUMAN BRAIN,

1864
01:12:46,440 --> 01:12:47,280
TECHNOLOGY AT SCARE FOR

1865
01:12:47,280 --> 01:12:49,160
MAMMALIAN BRAINS IS NOT THERE

1866
01:12:49,160 --> 01:12:50,680
AND WE'RE FOCUSING RIGHT NOW ON

1867
01:12:50,680 --> 01:12:51,920
DEVELOPING THE TOOLS IN ORDER TO

1868
01:12:51,920 --> 01:12:55,680
MAKE THAT HAPPEN  OVER THE IN

1869
01:12:55,680 --> 01:12:59,880
EX-FICHE OR  - NEXT FIVE OR TEN

1870
01:12:59,880 --> 01:13:03,520
YEARS, AND FINALLY TOOLS FOR

1871
01:13:03,520 --> 01:13:06,240
GAINING PRECISION TO ALLOW US TO

1872
01:13:06,240 --> 01:13:07,640
MODULATE NEURAL CIRCUITS FROM

1873
01:13:07,640 --> 01:13:09,600
THE BASIC DISCOVERY SIDE BUT

1874
01:13:09,600 --> 01:13:12,800
ALSO TO EVENTUALLY PROVIDE THE

1875
01:13:12,800 --> 01:13:14,520
FOUNDATION FOR PRECISION GENE

1876
01:13:14,520 --> 01:13:14,800
THERAPIES.

1877
01:13:14,800 --> 01:13:16,400
SO I'D LIKE TO GIVE AN UPDATE

1878
01:13:16,400 --> 01:13:18,640
WHERE WE ARE WITH THESE PROJECTS

1879
01:13:18,640 --> 01:13:21,560
AND TRANSITION TO TALK ABOUT

1880
01:13:21,560 --> 01:13:23,840
VARIOUS OTHER COOL FINDINGS

1881
01:13:23,840 --> 01:13:27,160
GOING ON IN PARTICULAR BY

1882
01:13:27,160 --> 01:13:28,240
NIDCD-FUNDED INVESTIGATORS.

1883
01:13:28,240 --> 01:13:28,480
OKAY.

1884
01:13:28,480 --> 01:13:34,320
SO HERE'S A LIST OF BRAIN 2.0

1885
01:13:34,320 --> 01:13:37,760
PROJECTS SEPARATED BY TOPIC AND

1886
01:13:37,760 --> 01:13:39,160
CURRENT AND ONGOING RFAs.

1887
01:13:39,160 --> 01:13:43,880
FIRST IS THE BRAIN CELL CENSUS,

1888
01:13:43,880 --> 01:13:46,200
PHASE III, WHICH WILL ENCOMPASS

1889
01:13:46,200 --> 01:13:49,360
A CONSORTIUM THAT WE REFER TO AS

1890
01:13:49,360 --> 01:13:52,440
BRAIN INITIATIVE CELL ATLAS

1891
01:13:52,440 --> 01:13:52,760
NETWORK.

1892
01:13:52,760 --> 01:13:55,480
THIS ABOUT BUILD ON SUCCESS OF

1893
01:13:55,480 --> 01:13:57,680
THE NETWORK WHICH IS SO FAR

1894
01:13:57,680 --> 01:13:59,200
FOCUSED MAINLY ON THE MOUSE

1895
01:13:59,200 --> 01:14:00,840
BRAIN BUT ALSO DEVELOPING TOOLS

1896
01:14:00,840 --> 01:14:02,280
FOR LOOKING AT LARGER BRAINS,

1897
01:14:02,280 --> 01:14:04,760
AND IN THE NEXT PHASE OF THE

1898
01:14:04,760 --> 01:14:06,400
CELL CENSUS PROJECT WILL SHIFT

1899
01:14:06,400 --> 01:14:07,600
EMPHASIS TO HUMANS.

1900
01:14:07,600 --> 01:14:10,120
THERE ARE THREE RFAs ISSUED

1901
01:14:10,120 --> 01:14:11,560
AND WE'RE EXPECTING FIRST AWARDS

1902
01:14:11,560 --> 01:14:14,080
TO BE ISSUED LATER THIS SUMMER.

1903
01:14:14,080 --> 01:14:16,160
SO THAT'S THE FIRST BIG PROJECT.

1904
01:14:16,160 --> 01:14:18,080
THE SECOND IS TO ORGANIZE

1905
01:14:18,080 --> 01:14:20,000
RESOURCES FOR BRAIN CELL TYPE

1906
01:14:20,000 --> 01:14:22,520
ACCESS AND MANIPULATION ACROSS

1907
01:14:22,520 --> 01:14:22,840
SPECIES.

1908
01:14:22,840 --> 01:14:25,640
WHAT WE CALL INSIDE THE CELL

1909
01:14:25,640 --> 01:14:26,480
TYPE-SPECIFIC ARMAMENTARIUM.

1910
01:14:26,480 --> 01:14:30,720
THIS IS TO DEVELOP TOOLS FOR

1911
01:14:30,720 --> 01:14:35,000
CELL ACCESS ACROSS MULTIPLE

1912
01:14:35,000 --> 01:14:37,720
SPECIES, AS WELL AS HUMAN CELLS

1913
01:14:37,720 --> 01:14:38,920
AND TISSUE.

1914
01:14:38,920 --> 01:14:41,680
THE LONG-TERM GOAL IS TO DEVELOP

1915
01:14:41,680 --> 01:14:43,080
NEW THERAPEUTIC STRATEGIES FOR

1916
01:14:43,080 --> 01:14:44,520
HUMAN BRAIN DISORDERS BUT FOR

1917
01:14:44,520 --> 01:14:46,720
NOW NEED TO DEVELOP BETTER

1918
01:14:46,720 --> 01:14:48,760
REAGENTS FOR GAINING ACCESS TO

1919
01:14:48,760 --> 01:14:51,720
CELL TYPES ACROSS MULTIPLE

1920
01:14:51,720 --> 01:14:51,960
SPECIES.

1921
01:14:51,960 --> 01:14:53,920
FIRST AWARDS HAVE BEEN MADE,

1922
01:14:53,920 --> 01:14:58,400
SECOND ROUND ABOUT TO BE ISSUED

1923
01:14:58,400 --> 01:14:59,920
IN JULY, COMPRISING VARIOUS

1924
01:14:59,920 --> 01:15:03,680
PILOT PROJECTS TO DEVELOP AND

1925
01:15:03,680 --> 01:15:04,960
VALIDATE TECHNOLOGIES FOR

1926
01:15:04,960 --> 01:15:05,440
ACCESS.

1927
01:15:05,440 --> 01:15:07,120
TO DATE, I DON'T MEAN TO BE

1928
01:15:07,120 --> 01:15:09,760
LIMITING, BUT TO DATE THESE

1929
01:15:09,760 --> 01:15:18,640
PROJECTS HAVE BEEN FOCUSING ON

1930
01:15:18,640 --> 01:15:19,760
ADENOASSOCIATED VIRUS DELIVERY

1931
01:15:19,760 --> 01:15:22,640
STRATEGIES AND ACTIVE RFA TO

1932
01:15:22,640 --> 01:15:29,400
BUILD CAPACITY FOR R&D AND
DES 

1933
01:15:29,400 --> 01:15:31,680
AND -- DISSEMINATION REQUIRING

1934
01:15:31,680 --> 01:15:32,640
PARTNERSHIP BETWEEN TOOL

1935
01:15:32,640 --> 01:15:34,640
DEVELOPERS AND A MINORITY

1936
01:15:34,640 --> 01:15:36,040
SERVING INSTITUTION OR

1937
01:15:36,040 --> 01:15:38,800
INSTITUTION IN AN IDeA

1938
01:15:38,800 --> 01:15:40,000
ELIGIBLE STATE.

1939
01:15:40,000 --> 01:15:41,080
THAT'S ARMAMENTARIUM.

1940
01:15:41,080 --> 01:15:44,680
AND FINALLY THE BRAIN

1941
01:15:44,680 --> 01:15:45,280
CONNECTIVITY ACROSS SCALES,

1942
01:15:45,280 --> 01:15:46,000
MICROCONNECTIVITY PROJECT WHICH

1943
01:15:46,000 --> 01:15:48,520
WE REFER TO AS BRAIN CONNECTS,

1944
01:15:48,520 --> 01:15:51,800
THE EFFORTS HERE WERE GUIDED BY

1945
01:15:51,800 --> 01:15:53,360
WORKSHOP WE HELD IN CONJUNCTION

1946
01:15:53,360 --> 01:15:56,360
WITH THE DEPARTMENT OF ENERGY'S

1947
01:15:56,360 --> 01:15:57,600
OFFICE OF SCIENCE, IN 2021.

1948
01:15:57,600 --> 01:15:59,880
AND HERE THE IDEA IS TO DEVELOP

1949
01:15:59,880 --> 01:16:03,000
AND LEVERAGE NEW TECHNOLOGIES TO

1950
01:16:03,000 --> 01:16:04,720
GENERATE COMPREHENSIVE ATLASES

1951
01:16:04,720 --> 01:16:06,480
OF BRAIN CONNECTIVITY ACROSS

1952
01:16:06,480 --> 01:16:08,560
WHOLE MAMMALIAN BRAINS FOCUSING

1953
01:16:08,560 --> 01:16:12,080
ON THE MOUSE, AT SYNAPSE

1954
01:16:12,080 --> 01:16:13,800
RESOLUTION, IN NON-HUMAN PRIMATE

1955
01:16:13,800 --> 01:16:16,720
AT HUMANS OR MICRON OR AXON

1956
01:16:16,720 --> 01:16:18,400
REVOLUTION, THESE WERE JUST

1957
01:16:18,400 --> 01:16:19,800
ISSUED THIS SPRING, AND FIRST

1958
01:16:19,800 --> 01:16:22,640
RECEIPT DATES ARE COMING UP THIS

1959
01:16:22,640 --> 01:16:23,000
SUMMER.

1960
01:16:23,000 --> 01:16:25,200
I SHOULD MENTION CONGRESS HAS

1961
01:16:25,200 --> 01:16:26,280
BEEN VERY GENEROUS SUPPORTING

1962
01:16:26,280 --> 01:16:28,960
EFFORTS, AND THEY HAVE PROVIDED

1963
01:16:28,960 --> 01:16:30,760
TO US FUNDS TO SPECIFICALLY

1964
01:16:30,760 --> 01:16:32,080
STAND UP THESE PROJECTS, SO STAY

1965
01:16:32,080 --> 01:16:32,280
TUNED.

1966
01:16:32,280 --> 01:16:33,720
THERE'S A LOT OF EXCITING STUFF

1967
01:16:33,720 --> 01:16:34,800
TO COME.

1968
01:16:34,800 --> 01:16:37,560
AGAIN, THE IDEA HERE IS BETWEEN

1969
01:16:37,560 --> 01:16:40,720
THE CELL ATLAS PROJECT AND

1970
01:16:40,720 --> 01:16:42,600
CONNECTIVITY PROJECT TO PROVIDE

1971
01:16:42,600 --> 01:16:44,680
WHAT NEURAL CIRCUITS LOOK LIKE

1972
01:16:44,680 --> 01:16:46,080
AND ARMAMENTARIUM PROJECT WILL

1973
01:16:46,080 --> 01:16:48,600
PROVIDE FOR US TOOLS TO ACCESS

1974
01:16:48,600 --> 01:16:51,480
THESE CIRCUITS WITH EVER GREATER

1975
01:16:51,480 --> 01:16:53,560
PRECISION WITH LONG-TERM GOAL OF

1976
01:16:53,560 --> 01:16:55,160
DEVELOPING PRECISION GENE

1977
01:16:55,160 --> 01:16:55,560
THERAPIES.

1978
01:16:55,560 --> 01:16:57,360
THAT'S A BIT FURTHER OFF IN THE

1979
01:16:57,360 --> 01:16:57,600
FUTURE.

1980
01:16:57,600 --> 01:17:00,360
WHAT I'D LIKE TO DO NOW IS

1981
01:17:00,360 --> 01:17:01,880
BRIEFLY HIGHLIGHT WHAT'S GOING

1982
01:17:01,880 --> 01:17:05,240
ON IN THE CELL CENSUS PROJECT,

1983
01:17:05,240 --> 01:17:07,560
IN WHICH I WAS ACTUALLY INVOLVED

1984
01:17:07,560 --> 01:17:09,200
AS AN INVESTIGATOR BEFORE I

1985
01:17:09,200 --> 01:17:11,280
JOINED NIH ABOUT TWO YEARS AGO,

1986
01:17:11,280 --> 01:17:17,080
AND THEN I'LL SEG RAY INTO SOME 

1987
01:17:17,080 --> 01:17:21,800
-- SEGUE USING BRAIN FUNDING BUT

1988
01:17:21,800 --> 01:17:23,320
INVOLVING VERY IMPORTANTLY

1989
01:17:23,320 --> 01:17:24,080
NIDCD-FUNDED INVESTIGATORS,

1990
01:17:24,080 --> 01:17:25,840
USING THIS TO HIGHLIGHT THE

1991
01:17:25,840 --> 01:17:28,880
OPPORTUNITIES FOR THIS COMMUNITY

1992
01:17:28,880 --> 01:17:30,600
TO BE INVOLVED IN THE COOL

1993
01:17:30,600 --> 01:17:31,520
TECHNOLOGY INITIATIVE.

1994
01:17:31,520 --> 01:17:32,040
OKAY.

1995
01:17:32,040 --> 01:17:35,480
SO THE PARTS LIST.

1996
01:17:35,480 --> 01:17:37,120
THIS WAS -- BRAIN INITIATIVE

1997
01:17:37,120 --> 01:17:39,280
CELL CENSUS PROJECT LAUNCHED IN

1998
01:17:39,280 --> 01:17:41,480
2014, STARTED WITH A SET OF TEN

1999
01:17:41,480 --> 01:17:43,200
PILOT PROJECTS THAT TOGETHER

2000
01:17:43,200 --> 01:17:44,800
COMPRISED THE BRAIN INITIATIVE

2001
01:17:44,800 --> 01:17:45,720
CELL CENSUS CONSORTIUM.

2002
01:17:45,720 --> 01:17:48,600
I WAS FORTUNATE TO BE AMONG THE

2003
01:17:48,600 --> 01:17:50,480
P.I.s IN THIS INITIAL EFFORT.

2004
01:17:50,480 --> 01:17:53,080
THE IDEA WAS AT THE TIME THIS

2005
01:17:53,080 --> 01:17:55,680
WAS IN 2014, A LOT OF THE SINGLE

2006
01:17:55,680 --> 01:17:56,960
CELL OMICS TECHNOLOGIES WERE

2007
01:17:56,960 --> 01:17:59,000
JUST COMING ON BOARD.

2008
01:17:59,000 --> 01:18:00,880
I THINK THE PROGRAM FOLKS HERE

2009
01:18:00,880 --> 01:18:04,560
AT NIH REALLY SAW AN OPPORTUNITY

2010
01:18:04,560 --> 01:18:06,880
TO LEVERAGE THIS OPPORTUNITY,

2011
01:18:06,880 --> 01:18:13,000
AND TO BEGIN A COMPREHENSIVE AND

2012
01:18:13,000 --> 01:18:15,080
RATIONAL ANALYSIS TO CELL A

2013
01:18:15,080 --> 01:18:17,720
COMPREHENSIVE CELL CENSUS.

2014
01:18:17,720 --> 01:18:20,240
NOW, THIS PILOT PHASE QUICKLY

2015
01:18:20,240 --> 01:18:23,520
GOT SCALED UP INTO WHAT IS

2016
01:18:23,520 --> 01:18:24,880
CURRENTLY CALLED THE BRAIN CELL

2017
01:18:24,880 --> 01:18:25,520
CENSUS NETWORK.

2018
01:18:25,520 --> 01:18:27,080
AGAIN I WAS FORTUNATE TO BE A

2019
01:18:27,080 --> 01:18:29,800
P.I. IN THIS EFFORT.

2020
01:18:29,800 --> 01:18:32,000
THE ASPIRATIONAL GOAL TO

2021
01:18:32,000 --> 01:18:32,960
REVOLUTIONIZE ABILITY TO

2022
01:18:32,960 --> 01:18:34,720
CLASSIFY BRAIN CELL TYPES BASED

2023
01:18:34,720 --> 01:18:37,120
ON INTEGRATED ANALYSIS OF

2024
01:18:37,120 --> 01:18:38,120
MOLECULAR ANATOMICAL AND

2025
01:18:38,120 --> 01:18:39,120
PHYSIOLOGICAL PROPERTIES.

2026
01:18:39,120 --> 01:18:41,960
WHILE THERE'S BEEN A LOT OF

2027
01:18:41,960 --> 01:18:44,480
EMPHASIS AND PRESS ABOUT SINGLE

2028
01:18:44,480 --> 01:18:49,400
CELL TRANSCRIPT OMICS AND

2029
01:18:49,400 --> 01:18:51,920
EPIGENOMICS THIS IS JUST THE

2030
01:18:51,920 --> 01:18:54,560
FOUNDATION TO BUILD A

2031
01:18:54,560 --> 01:18:55,640
MULTI-MODAL ANALYSIS.

2032
01:18:55,640 --> 01:18:57,440
A TRAUNCH OF PAPERS WAS

2033
01:18:57,440 --> 01:18:59,880
PUBLISHED, WE HAD A TAKEOVER OF

2034
01:18:59,880 --> 01:19:05,120
THE OCTOBER 7 ISSUE OF "NATURE"

2035
01:19:05,120 --> 01:19:08,000
IN 2021, WITH 17 PAPERS IN

2036
01:19:08,000 --> 01:19:12,160
"NATURE" AND 10 PUBLICATIONS IN

2037
01:19:12,160 --> 01:19:14,200
"NATURE" SISTER JOURNALS

2038
01:19:14,200 --> 01:19:15,520
DESCRIBING MULTI-MODAL ANALYSIS

2039
01:19:15,520 --> 01:19:19,240
OF CELL TYPES IN THE MAMMALIAN

2040
01:19:19,240 --> 01:19:20,800
PRIMARY MOTOR CORTEX.

2041
01:19:20,800 --> 01:19:25,440
SO HERE AGAIN WE USE NOT ONLY 

2042
01:19:25,440 --> 01:19:27,240
SINGLE CELL RNA SEQUENCING,

2043
01:19:27,240 --> 01:19:29,440
SINGLE CELL TRANSCRIPTOMICS BUT

2044
01:19:29,440 --> 01:19:34,400
THIS ANALYSIS WAS COMBINED WITH

2045
01:19:34,400 --> 01:19:38,680
SINGLE CELL EPIGENOMICS LOOKING

2046
01:19:38,680 --> 01:19:42,720
AT DNA METHYLATION AND TO MORE

2047
01:19:42,720 --> 01:19:45,960
LIMITED EXTENT CONNECTIVITY, TO

2048
01:19:45,960 --> 01:19:47,560
CHARACTERIZE THE MOLECULAR

2049
01:19:47,560 --> 01:19:48,160
PROPERTIES, SPATIAL

2050
01:19:48,160 --> 01:19:49,640
DISTRIBUTION, PHYSIOLOGY, ET

2051
01:19:49,640 --> 01:19:55,920
CETERA, OF THESE CELL TYPES. 

2052
01:19:55,920 --> 01:19:58,000
ACROSS A NUMBER OF SPECIES, THE

2053
01:19:58,000 --> 01:19:59,440
MOUSE, NON-HUMAN PRIMATE, AND

2054
01:19:59,440 --> 01:20:02,080
HUMAN BRAIN, USING A WIDE

2055
01:20:02,080 --> 01:20:04,240
VARIETY OF TECHNIQUES HERE.

2056
01:20:04,240 --> 01:20:09,280
AND THIS LED TO ELUCIDATION OF

2057
01:20:09,280 --> 01:20:09,920
ORGANIZATIONAL PRINCIPLES

2058
01:20:09,920 --> 01:20:12,480
UNDERLYING DIVERSIFICATION OF

2059
01:20:12,480 --> 01:20:13,440
CELL TYPES, HIERARCHICAL

2060
01:20:13,440 --> 01:20:20,440
ORGANIZATION OF CELL  TYPES AND

2061
01:20:20,440 --> 01:20:21,760
SAW REMARKABLE CONSERVATION

2062
01:20:21,760 --> 01:20:25,160
BETWEEN MOUSE, MARMOSET, HUMANS,

2063
01:20:25,160 --> 01:20:27,200
 SETTING THE STAGE FOR HUMAN

2064
01:20:27,200 --> 01:20:28,440
BRAIN ATLAS.

2065
01:20:28,440 --> 01:20:30,800
AT THE HIGHER LEVELS WE SEE

2066
01:20:30,800 --> 01:20:32,720
EXTREME CONSERVATION BETWEEN ALL

2067
01:20:32,720 --> 01:20:34,080
OF THESE MAMMALIAN SPECIES AND

2068
01:20:34,080 --> 01:20:35,640
WHERE YOU START TO SEE

2069
01:20:35,640 --> 01:20:39,600
DIFFERENCES OF VARIATION IS

2070
01:20:39,600 --> 01:20:40,640
FINER LEAVES, SPECIALIZATION.

2071
01:20:40,640 --> 01:20:41,760
OF YOU START TO SEE.

2072
01:20:41,760 --> 01:20:43,520
THIS IS GOING TO BE GREAT GROUND

2073
01:20:43,520 --> 01:20:44,440
FOR FUTURE WORK.

2074
01:20:44,440 --> 01:20:47,040
I WOULD LIKE TO HIGHLIGHT POWER

2075
01:20:47,040 --> 01:20:47,720
OF TEAM SCIENCE.

2076
01:20:47,720 --> 01:20:49,440
IT DOESN'T WORK FOR EVERYTHING

2077
01:20:49,440 --> 01:20:51,760
BUT FOR SOME THINGS IT'S

2078
01:20:51,760 --> 01:20:52,760
CRITICAL.

2079
01:20:52,760 --> 01:20:56,120
THIS EFFORT INVOLVED OVER 250

2080
01:20:56,120 --> 01:20:57,960
RESEARCHERS FROM 45 INSTITUTIONS

2081
01:20:57,960 --> 01:20:59,000
ACROSS THREE CONTINENTS AND I

2082
01:20:59,000 --> 01:21:00,800
WOULD ARGUE THIS IS

2083
01:21:00,800 --> 01:21:03,000
UNPRECEDENTED FOR THE FIELD OF

2084
01:21:03,000 --> 01:21:03,880
NEUROSCIENCE BUT REALLY IS I

2085
01:21:03,880 --> 01:21:06,720
THINK THE KEY TO MOVING THIS

2086
01:21:06,720 --> 01:21:09,680
LARGE PROJECT FORWARD WHICH WILL

2087
01:21:09,680 --> 01:21:10,640
PROVIDE RESOURCES FOR

2088
01:21:10,640 --> 01:21:12,000
HYPOTHESIS-DRIVEN RESEARCH THAT

2089
01:21:12,000 --> 01:21:16,600
REALLY WILL ELUCIDATE THE 

2090
01:21:16,600 --> 01:21:17,800
MECHANISMS UNDERLYING BRAIN

2091
01:21:17,800 --> 01:21:18,680
FUNCTION.

2092
01:21:18,680 --> 01:21:21,080
SO, AS I MENTIONED BEFORE THERE

2093
01:21:21,080 --> 01:21:23,200
REALLY IS A GREAT ALIGNMENT OF

2094
01:21:23,200 --> 01:21:25,760
MISSIONS BETWEEN THE BRAIN

2095
01:21:25,760 --> 01:21:29,360
INITIATIVE AND THE NIDCD

2096
01:21:29,360 --> 01:21:29,600
MISSION.

2097
01:21:29,600 --> 01:21:31,680
"BRAIN" IS BY DESIGN DISEASE OR

2098
01:21:31,680 --> 01:21:32,880
SYSTEM AGNOSTIC BUT THAT'S NOT

2099
01:21:32,880 --> 01:21:35,840
TO SAY THAT WE AREN'T GOING TO

2100
01:21:35,840 --> 01:21:37,040
DEVELOP SOME GREAT TOOLS BASED

2101
01:21:37,040 --> 01:21:46,840
ON I.C.-SPECIFIC NEEDS AND SEE

2102
01:21:46,840 --> 01:21:47,360
PRINCIPLES EMERGING.

2103
01:21:47,360 --> 01:21:48,240
INVESTIGATORS ARE THE LEADING

2104
01:21:48,240 --> 01:21:50,880
EDGE OF DEVELOPING TOOLS IN A

2105
01:21:50,880 --> 01:21:53,920
VARIETY OF AREAS INCLUDING

2106
01:21:53,920 --> 01:21:55,280
INVESTIGATING CIRCUMSTANCES AND

2107
01:21:55,280 --> 01:21:58,240
COMPUTATION UNDERLYING AUDITORY

2108
01:21:58,240 --> 01:21:59,560
PROCESSING AND VESTIBULAR

2109
01:21:59,560 --> 01:22:00,080
PROCESSING, UNDERSTANDING

2110
01:22:00,080 --> 01:22:02,800
PRINCIPLES OF SPEECH AND

2111
01:22:02,800 --> 01:22:04,680
LANGUAGE, LIMIT OF ELIMINATING

2112
01:22:04,680 --> 01:22:05,600
MECHANISMS OF CHEMO SENSATION,

2113
01:22:05,600 --> 01:22:06,720
SMELL AND TASTE, NEAR AND DEAR

2114
01:22:06,720 --> 01:22:07,400
TO MY HEART.

2115
01:22:07,400 --> 01:22:11,440
I STILL CONTINUE TO WORK ON THE

2116
01:22:11,440 --> 01:22:17,800
OLFACTORY SYSTEM,  AND NEXT

2117
01:22:17,800 --> 01:22:20,760
GENERATION SENSORY AND

2118
01:22:20,760 --> 01:22:21,400
SENSORIMOTOR NEURAL PROSTHESIS,

2119
01:22:21,400 --> 01:22:25,360
A LOT OF GREAT SCIENCE GOING ON

2120
01:22:25,360 --> 01:22:29,120
IN NIDCD AND SUPPORTED PROJECTS

2121
01:22:29,120 --> 01:22:30,320
OF GREAT MUTUAL INTEREST, THERE

2122
01:22:30,320 --> 01:22:34,160
COULD BE A LOT OF TERRIFIC

2123
01:22:34,160 --> 01:22:35,760
SYNERGY HERE.

2124
01:22:35,760 --> 01:22:37,400
SO LET ME HIGHLIGHT A FEW

2125
01:22:37,400 --> 01:22:39,400
PROJECTS, I'LL START CLOSE TO

2126
01:22:39,400 --> 01:22:43,760
HOME IN MY DOMAIN, IN THE

2127
01:22:43,760 --> 01:22:44,840
OLFACTORY SYSTEM.

2128
01:22:44,840 --> 01:22:48,560
AS I THINK MANY KNOW SOON AFTER

2129
01:22:48,560 --> 01:22:50,880
THE COVID PANDEMIC HIT, PEOPLE

2130
01:22:50,880 --> 01:22:53,480
HAD NOTICED, INVESTIGATORS AND

2131
01:22:53,480 --> 01:22:55,120
CLINICIANS HAD NOTICED THIS

2132
01:22:55,120 --> 01:23:00,840
INTERESTING ASSOCIATION OF

2133
01:23:00,840 --> 01:23:02,920
ANOSMIA WITH PATIENTS WHO

2134
01:23:02,920 --> 01:23:05,040
DEVELOPED THE SYMPTOMS OF

2135
01:23:05,040 --> 01:23:06,320
SARS-COV-2 INFECTION, OR COVID.

2136
01:23:06,320 --> 01:23:09,040
NOW, SOON AFTER THE ONSET OF

2137
01:23:09,040 --> 01:23:13,080
PANDEMIC IN 2020 I GOT A CALL

2138
01:23:13,080 --> 01:23:15,000
FROM A GOOD FRIEND, BOB, AT

2139
01:23:15,000 --> 01:23:16,160
HARVARD MEDICAL SCHOOL.

2140
01:23:16,160 --> 01:23:18,240
HE AND OTHERS WERE INTRIGUED BY

2141
01:23:18,240 --> 01:23:19,040
THIS ASSOCIATION.

2142
01:23:19,040 --> 01:23:20,640
AND AS YOU RECALL, MANY WERE

2143
01:23:20,640 --> 01:23:22,840
SITTING AT HOME NOT IN A LAB,

2144
01:23:22,840 --> 01:23:25,120
AND BOB AND HIS LAB AND

2145
01:23:25,120 --> 01:23:26,920
COLLEAGUES WERE STILL VERY

2146
01:23:26,920 --> 01:23:29,280
ACTIVELY USING THEIR BRAINS.

2147
01:23:29,280 --> 01:23:32,120
AND THE REAL QUESTION WAS WHAT

2148
01:23:32,120 --> 01:23:34,480
IS UNDERLYING THIS ASSOCIATION

2149
01:23:34,480 --> 01:23:35,920
BETWEEN COVID AND ANOSMIA?

2150
01:23:35,920 --> 01:23:37,240
AND WHAT IF ANYTHING MIGHT IT

2151
01:23:37,240 --> 01:23:39,040
TELL US ABOUT THE BROADER

2152
01:23:39,040 --> 01:23:41,120
RAMIFICATIONS OF COVID ON THE

2153
01:23:41,120 --> 01:23:42,760
PATIENT'S LET AND RECOVERY,

2154
01:23:42,760 --> 01:23:44,040
SPECIFICALLY EFFECTS ON NERVOUS

2155
01:23:44,040 --> 01:23:44,280
SYSTEM.

2156
01:23:44,280 --> 01:23:46,160
BOB APPROACHED THIS BY ASKING A

2157
01:23:46,160 --> 01:23:47,440
SIMPLE QUESTION WHICH IS ON

2158
01:23:47,440 --> 01:23:54,160
WHICH CELLS IN THE PERIPHERAL

2159
01:23:54,160 --> 01:23:56,840
OLFACTORY SYSTEM ARE RECEPTORS

2160
01:23:56,840 --> 01:23:59,480
EXPRESSED, RECEPTOR IS A ACE-2,

2161
01:23:59,480 --> 01:24:01,800
PROTEOMIC RAILS IS REQUIRED FOR

2162
01:24:01,800 --> 01:24:03,880
VIRAL ENTRY THROUGH THIS

2163
01:24:03,880 --> 01:24:05,400
RECEPTOR MEDIATED MECHANISM.

2164
01:24:05,400 --> 01:24:08,040
SO, THE APPROACH WAS HE WENT

2165
01:24:08,040 --> 01:24:11,320
ABOUT TO MINE THE AVAILABLE

2166
01:24:11,320 --> 01:24:12,600
PUBLISHED DATABASES, ON BOTH

2167
01:24:12,600 --> 01:24:15,800
BULK AND SINGLE CELL RNA

2168
01:24:15,800 --> 01:24:20,280
SEQUENCING ON OLFACTORY

2169
01:24:20,280 --> 01:24:23,240
EPITHELIUM, ASKING ME IF I I

2170
01:24:23,240 --> 01:24:26,840
MINDED I IF HE USED A DATASET I

2171
01:24:26,840 --> 01:24:27,760
PUBLISHED.

2172
01:24:27,760 --> 01:24:28,920
THEY ARE PUBLIC DOMAIN, DO AS

2173
01:24:28,920 --> 01:24:31,120
YOU WISH, BUT I GOT TO TELL YOU

2174
01:24:31,120 --> 01:24:33,000
THE STUDIES WE PUBLISHED TO DATE

2175
01:24:33,000 --> 01:24:36,720
WERE FEWER THAN ABOUT A THOUSAND

2176
01:24:36,720 --> 01:24:47,280
CELLS, USING THE OLDER LABORIOUS

2177
01:24:47,720 --> 01:24:47,960
TECHNOLOGIES.

2178
01:24:47,960 --> 01:24:49,760
I HAVE 50,000 CELLS IN MY POCKET

2179
01:24:49,760 --> 01:24:51,720
WE HAVEN'T PUBLISHED, LEADING TO

2180
01:24:51,720 --> 01:24:54,120
A COLLABORATION BETWEEN MY LAB,

2181
01:24:54,120 --> 01:24:57,320
BOB'S LAB, EVENTUALLY WITH THE

2182
01:24:57,320 --> 01:25:04,840
LABS AT DUKE AS WELL AS THE U.K.

2183
01:25:04,840 --> 01:25:06,160
SO, TOGETHER WE USED SINGLE CELL

2184
01:25:06,160 --> 01:25:08,680
RNA SEQUENCING NOT JUST OF MOUSE

2185
01:25:08,680 --> 01:25:10,680
OLFACTORY EPITHELIUM BUT TURNS

2186
01:25:10,680 --> 01:25:13,160
OUT EVENTUALLY WITH HUMANS,

2187
01:25:13,160 --> 01:25:17,320
HUMAN OLFACTORY EPITHELIUM AND

2188
01:25:17,320 --> 01:25:22,360
HOME OLFACTORY BULB TO LOOK FOR

2189
01:25:22,360 --> 01:25:26,720
ACE-2 AND TMPRSS EXPRESSION, 

2190
01:25:26,720 --> 01:25:33,640
CRITICAL FOR SARS-COV-2 ENTRY, 

2191
01:25:33,640 --> 01:25:35,080
EXPRESSED IN THE SUSTENCARULAR

2192
01:25:35,080 --> 01:25:37,360
CELLS BUT NOT OLFACTORY NEURONS,

2193
01:25:37,360 --> 01:25:41,480
I THINK BY NOW THIS HAS BEEN

2194
01:25:41,480 --> 01:25:46,520
WELL VALIDATED.

2195
01:25:46,520 --> 01:25:57,080
THIS IS HISTOCHEMISTRY IN 2020 

2196
01:26:00,080 --> 01:26:02,280
EXPRESSION OF THESE MOLECULES.

2197
01:26:02,280 --> 01:26:08,240
THIS WAS FURTHER VALIDATED IN

2198
01:26:08,240 --> 01:26:09,440
HUMAN AUTOPSY MATERIAL AT MAX

2199
01:26:09,440 --> 01:26:11,720
PLANCK WITH OTHER COLLEAGUES I

2200
01:26:11,720 --> 01:26:12,840
BELIEVE IN BELGIUM.

2201
01:26:12,840 --> 01:26:15,120
SO, AGAIN, THIS IS A BIT

2202
01:26:15,120 --> 01:26:16,440
CONTROVERSIAL BUT I THINK THE

2203
01:26:16,440 --> 01:26:22,040
PAPER DOES PUT THIS TO REST,

2204
01:26:22,040 --> 01:26:24,440
SHOWING THEY COULD NEVER FIND

2205
01:26:24,440 --> 01:26:25,760
SARS-COV-2 VARIANT IN ANYTHING

2206
01:26:25,760 --> 01:26:26,840
BUT SUSTENCARULAR CELLS AND

2207
01:26:26,840 --> 01:26:30,360
NEVER SAW IT IN NEURONS.

2208
01:26:30,360 --> 01:26:32,880
STILL BASIC QUESTION HOW

2209
01:26:32,880 --> 01:26:35,080
SARS-COV-2 INFECTION IS CAUSING

2210
01:26:35,080 --> 01:26:43,280
ANOSMIA, HERE IS A STUDY JUST

2211
01:26:43,280 --> 01:26:45,600
PUBLISHED IN "CELL," RAPID

2212
01:26:45,600 --> 01:26:46,360
DOWNREGULATION OF OTORECEPTOR

2213
01:26:46,360 --> 01:26:48,000
GENE EXPRESSION AND GENES

2214
01:26:48,000 --> 01:26:49,760
ENCODING SIGNALING MOLECULES IN

2215
01:26:49,760 --> 01:26:50,840
THE SIGNALING CASCADE.

2216
01:26:50,840 --> 01:26:52,600
AND THEY SAW THIS BOTH IN

2217
01:26:52,600 --> 01:26:54,240
HAMSTERS AS WELL AS HUMANS,

2218
01:26:54,240 --> 01:26:58,840
HAMSTERS HAVE BEEN A GREAT MODEL

2219
01:26:58,840 --> 01:27:00,680
FOR LOOKING AT COVID,

2220
01:27:00,680 --> 01:27:02,560
PROGRESSION OF COVID.

2221
01:27:02,560 --> 01:27:06,040
WHAT THEY FOUND WAS DISRUPTION

2222
01:27:06,040 --> 01:27:07,160
OF NUCLEAR ARCHITECTURE AS

2223
01:27:07,160 --> 01:27:10,520
REQUIRED FOR HIGH LEVEL

2224
01:27:10,520 --> 01:27:11,520
OTORECEPTOR EXPRESSION AND

2225
01:27:11,520 --> 01:27:14,840
OLFACTORY SENSORY NEURONS, THIS

2226
01:27:14,840 --> 01:27:25,120
EFFECT IS NON-CELL AUTONOMOUS.

2227
01:27:25,120 --> 01:27:29,080
INI BELIEVE THIS MAY HAVE

2228
01:27:29,080 --> 01:27:35,400
IMPLICATIONS NOT ONLY FOR AS 

2229
01:27:35,400 --> 01:27:39,800
THOSE WITH COVID AND WITH

2230
01:27:39,800 --> 01:27:40,480
NEURODEGENERATIVE DISORDER

2231
01:27:40,480 --> 01:27:41,000
INCLUDING PARKINSON'S AND

2232
01:27:41,000 --> 01:27:43,640
ALZHEIMER'S DISEASE. 

2233
01:27:43,640 --> 01:27:46,040
IT'S COOL TO SEE HOW WE CAN TAKE

2234
01:27:46,040 --> 01:27:47,320
CELL CENSUS TYPE INFORMATION AND

2235
01:27:47,320 --> 01:27:52,960
USE THAT AS PLATFORM FOR

2236
01:27:52,960 --> 01:27:54,480
DEVELOPING MECHANISTIC STUDIES.

2237
01:27:54,480 --> 01:27:57,640
SO HERE'S A COOL STUDY LOOKING

2238
01:27:57,640 --> 01:27:59,160
AT THE PROCESSING OF SPEECH IN

2239
01:27:59,160 --> 01:27:59,400
HUMANS.

2240
01:27:59,400 --> 01:28:02,560
THIS IS A STUDY FROM EDDIE

2241
01:28:02,560 --> 01:28:05,160
CHANG'S LAB AT UCSF CONDUCTED BY

2242
01:28:05,160 --> 01:28:06,960
LIBERTY HAMILTON NOW ASSISTANT

2243
01:28:06,960 --> 01:28:09,360
PROFESSOR AT U.T. AUSTIN,

2244
01:28:09,360 --> 01:28:11,200
LIBERTY WAS A POSTDOC WITH

2245
01:28:11,200 --> 01:28:11,640
EDDIE.

2246
01:28:11,640 --> 01:28:17,640
I HAVE TO SAY LIBERTY WAS ALSO A

2247
01:28:17,640 --> 01:28:18,360
GRADUATE STUDENT AT UC-BERKELEY

2248
01:28:18,360 --> 01:28:21,400
IN THE PROGRAM I DIRECTED BEFORE

2249
01:28:21,400 --> 01:28:23,040
COMING TO NIH.

2250
01:28:23,040 --> 01:28:25,240
THEY USED RECORDINGS AND

2251
01:28:25,240 --> 01:28:26,000
STIMULATION ACROSS HUMAN

2252
01:28:26,000 --> 01:28:27,880
AUDITORY CORTEX TO DETERMINE HOW

2253
01:28:27,880 --> 01:28:29,080
INFORMATION IS PROCESSED ACROSS

2254
01:28:29,080 --> 01:28:30,680
THESE REGIONS AND HOW CUES IN

2255
01:28:30,680 --> 01:28:33,000
THE SPEECH SIGNAL ARE MAPPED

2256
01:28:33,000 --> 01:28:36,520
ACROSS THE ENTIRE AUDITORY

2257
01:28:36,520 --> 01:28:36,840
CORTEX.

2258
01:28:36,840 --> 01:28:39,360
THEY FOUND THAT THROUGH RESPONSE

2259
01:28:39,360 --> 01:28:40,640
LATENCY AND RECEPTOR FIELD

2260
01:28:40,640 --> 01:28:42,600
ANALYSES THE INFORMATION IS NOT

2261
01:28:42,600 --> 01:28:46,440
PROCESSED SERIALLY BUT IN

2262
01:28:46,440 --> 01:28:47,200
PARALLEL ACROSS VARIOUS REGIONS

2263
01:28:47,200 --> 01:28:50,800
OF THE PRIMARY AND NON-PRIMARY

2264
01:28:50,800 --> 01:28:52,360
AUDITORY CORTICES, ARGUES

2265
01:28:52,360 --> 01:28:53,880
AGAINST SIMPLE HIERARCHY OF

2266
01:28:53,880 --> 01:28:54,440
CORTICAL PROCESSING.

2267
01:28:54,440 --> 01:28:57,040
WHAT THEY FOUND IN CASE STUDY

2268
01:28:57,040 --> 01:28:59,240
USING DIRECT STIMULATION OF

2269
01:28:59,240 --> 01:29:01,520
EITHER AUDITORY CORTEX OR

2270
01:29:01,520 --> 01:29:06,120
REGIONS IN THE SUPERIOR TEMPORAL

2271
01:29:06,120 --> 01:29:09,440
GYRUS AUDITOR CORTEX IS NEITHER

2272
01:29:09,440 --> 01:29:14,560
NECESSARY FOR SPEECH PERCEPTION

2273
01:29:14,560 --> 01:29:18,160
AND FOUND STIMULATION IN STG

2274
01:29:18,160 --> 01:29:20,480
CAUSED DISRUPTION IN PATIENT'S

2275
01:29:20,480 --> 01:29:22,000
ABILITY TO HEAR AND REPEAT A

2276
01:29:22,000 --> 01:29:28,840
WORD THAT WAS GIVEN TO HER. 

2277
01:29:28,840 --> 01:29:29,720
COOL STUFF.

2278
01:29:29,720 --> 01:29:30,840
HIGHLIGHTING THE INVESTIGATIONS

2279
01:29:30,840 --> 01:29:33,080
OF SPEECH PROCESSING IN HUMANS

2280
01:29:33,080 --> 01:29:34,960
BUT REALLY ALSO HIGHLIGHTING THE

2281
01:29:34,960 --> 01:29:35,480
RESEARCH OPPORTUNITIES IN

2282
01:29:35,480 --> 01:29:37,880
HUMANS, WHAT WE CAN ACTUALLY

2283
01:29:37,880 --> 01:29:39,680
LEARN ABOUT HUMAN NEURAL CIRCUIT

2284
01:29:39,680 --> 01:29:41,720
FUNCTION IN THESE COMPLEX

2285
01:29:41,720 --> 01:29:43,440
BEHAVIORS.

2286
01:29:43,440 --> 01:29:52,160
HERE'S A COOL STUDY, CARRIED OUT

2287
01:29:52,160 --> 01:29:55,560
BASED AT STANFORD, TO DEVELOP

2288
01:29:55,560 --> 01:29:56,720
BRAIN-COMPUTER INTERFACES AS

2289
01:29:56,720 --> 01:29:58,280
NEURAL PROSTHESES.

2290
01:29:58,280 --> 01:30:01,680
THEY HAD A PARALYZED PATIENT,

2291
01:30:01,680 --> 01:30:04,000
THEY USED RECORDINGS AND

2292
01:30:04,000 --> 01:30:07,920
INTERPRETATIONS OF NEURAL

2293
01:30:07,920 --> 01:30:08,680
SIGNALS ACROSS ELECTRODES PLACED

2294
01:30:08,680 --> 01:30:13,240
IN THE BRAIN TO ALLOW THIS

2295
01:30:13,240 --> 01:30:14,640
INDIVIDUAL TO COMMUNICATE IN

2296
01:30:14,640 --> 01:30:20,640
CONTRAST TO EDDIE CHANG'S VERY

2297
01:30:20,640 --> 01:30:21,960
FAMOUS SPEECH PROSTHESES TO TURN

2298
01:30:21,960 --> 01:30:23,400
ELECTRICAL ACTIVITY IN THE BRAIN

2299
01:30:23,400 --> 01:30:27,600
TO TEXT.

2300
01:30:27,600 --> 01:30:28,600
SO, USING THIS BRAIN-COMPUTER

2301
01:30:28,600 --> 01:30:31,400
INTERFACE COULD ALLOW THIS

2302
01:30:31,400 --> 01:30:33,080
PATIENT TO TYPE CHARACTERS AT 90

2303
01:30:33,080 --> 01:30:36,040
CHARACTERS PER MINUTE WITH GREAT

2304
01:30:36,040 --> 01:30:37,800
ACCURACY BY SIMPLY IMAGINING THE

2305
01:30:37,800 --> 01:30:39,520
KEY STROKES OF WRITING THE

2306
01:30:39,520 --> 01:30:41,920
LETTERS THEMSELVES.

2307
01:30:41,920 --> 01:30:45,240
SO THEY WOULD RECORD NEURAL

2308
01:30:45,240 --> 01:30:46,680
ACTIVITY, USE RECURRING NEURAL

2309
01:30:46,680 --> 01:30:49,360
NETWORK TO LEARN ACTIVITY

2310
01:30:49,360 --> 01:30:51,320
ASSOCIATIONS BETWEEN THE

2311
01:30:51,320 --> 01:30:53,200
IMAGINED LETTERS AND THE ACTUAL

2312
01:30:53,200 --> 01:30:57,240
WRITTEN LETTERS, AND THEN TO USE

2313
01:30:57,240 --> 01:31:00,000
THIS TO CATEGORIZE EACH IMAGINED

2314
01:31:00,000 --> 01:31:01,760
KEY STROKE BASED ON CHANGES IN

2315
01:31:01,760 --> 01:31:03,040
ACTIVITY TO CLUSTER THEM AND

2316
01:31:03,040 --> 01:31:07,360
AGAIN TO ALLOW THIS PATIENT TO

2317
01:31:07,360 --> 01:31:08,240
LITERALLY TYPE OUT WORDS ABOUT

2318
01:31:08,240 --> 01:31:11,040
AS FAST AS I CAN ON A BAD DAY,

2319
01:31:11,040 --> 01:31:14,880
CLICKING ON MY iPHONE,

2320
01:31:14,880 --> 01:31:16,440
REMARKABLE TO INTERPRET THIS

2321
01:31:16,440 --> 01:31:19,800
INFORMATION AND TURN IT INTO A

2322
01:31:19,800 --> 01:31:23,320
COMMUNICATION PROSTHETIC DEVICE.

2323
01:31:23,320 --> 01:31:25,080
NOW, I'VE HIGHLIGHTED TWO

2324
01:31:25,080 --> 01:31:30,120
STUDIES INVOLVE  INVOLVING

2325
01:31:30,120 --> 01:31:30,640
HUMANS.

2326
01:31:30,640 --> 01:31:32,760
WE HAVE TO BE MINDFUL AS WE WORK

2327
01:31:32,760 --> 01:31:34,280
WITH HUMANS AND DEVELOP

2328
01:31:34,280 --> 01:31:35,400
TECHNOLOGIES THAT CAN AFFECT

2329
01:31:35,400 --> 01:31:39,080
HUMAN BRAIN FUNCTION ARE THE

2330
01:31:39,080 --> 01:31:39,600
ETHICAL, LEGAL, SOCIETAL

2331
01:31:39,600 --> 01:31:40,760
IMPLICATIONS OF THIS WORK.

2332
01:31:40,760 --> 01:31:41,840
TO THIS END THE BRAIN INITIATIVE

2333
01:31:41,840 --> 01:31:45,080
HAS BEEN QUITE  DILIGENT IN

2334
01:31:45,080 --> 01:31:46,000
INCORPORATING THESE ISSUES INTO

2335
01:31:46,000 --> 01:31:48,760
ALL WE DO AND WE HAVE AN ACTIVE

2336
01:31:48,760 --> 01:31:50,400
NEUROETHICS WORKING GROUP THAT

2337
01:31:50,400 --> 01:31:54,040
ADVISES US ON THESE ISSUES, THEY

2338
01:31:54,040 --> 01:31:55,320
HAVE HELPED US DEVELOP GUIDING

2339
01:31:55,320 --> 01:31:59,560
PRINCIPLES AND WE HAVE A TEAM 

2340
01:31:59,560 --> 01:32:06,800
FOCUSED ON  ON  ON THESE THESE

2341
01:32:06,800 --> 01:32:07,440
ISSUES.

2342
01:32:07,440 --> 01:32:12,000
IN JUNE WE HAVE OUR EIGHTH OF

2343
01:32:12,000 --> 01:32:22,680
EIGHTH MEETING, THREE TALKS FROM

2344
01:32:22,680 --> 01:32:23,480
PROFESSOR BAUTISTA, AND OTHERS,

2345
01:32:23,480 --> 01:32:25,080
YOU CAN FIND THE INFORMATION ON

2346
01:32:25,080 --> 01:32:26,520
THE WEBSITE AND STAY UP TO DATE

2347
01:32:26,520 --> 01:32:28,520
ON ALL WE DO BY VISITING OUR

2348
01:32:28,520 --> 01:32:30,800
WEBSITE AND I NEED TO FINISH BY

2349
01:32:30,800 --> 01:32:31,920
ACKNOWLEDGING THE GREAT FOLKS

2350
01:32:31,920 --> 01:32:36,360
BEHIND ALL OF OUR WORK, I HAVE A

2351
01:32:36,360 --> 01:32:37,240
TERRIFIC GROUP AROUND ME IN THE

2352
01:32:37,240 --> 01:32:41,080
OFFICE OF THE BRAIN DIRECTOR AND

2353
01:32:41,080 --> 01:32:42,960
OVER 100 STAFF CONTRIBUTING TO

2354
01:32:42,960 --> 01:32:45,720
THE EFFORT INCLUDING MANY OF OUR

2355
01:32:45,720 --> 01:32:46,800
COLLEAGUES HERE AT NIDCD, YOU

2356
01:32:46,800 --> 01:32:49,000
CAN SEE ON THE SLIDE.

2357
01:32:49,000 --> 01:32:50,320
I'LL STOP HERE, APOLOGIES FOR

2358
01:32:50,320 --> 01:32:51,280
RUNNING A BIT LATE.

2359
01:32:51,280 --> 01:32:52,920
IF THERE'S TIME FOR QUESTIONS

2360
01:32:52,920 --> 01:32:55,360
I'M HAPPY TO TAKE THEM.

2361
01:32:55,360 --> 01:32:57,960
>> NOT AT ALL, JOHN.

2362
01:32:57,960 --> 01:32:59,160
THAT WAS FANTASTIC.

2363
01:32:59,160 --> 01:33:00,400
WELCOME ANY QUESTIONS FROM

2364
01:33:00,400 --> 01:33:02,760
COUNCIL MEMBERS.

2365
01:33:02,760 --> 01:33:08,360
 

2366
01:33:08,360 --> 01:33:10,560
JOHN, I HAVE A QUESTION.

2367
01:33:10,560 --> 01:33:12,280
YOU MENTIONED THE CURES FUNDING

2368
01:33:12,280 --> 01:33:15,480
THAT WILL GIVE A BIG BUMP TO

2369
01:33:15,480 --> 01:33:17,400
YOUR BUDGET NEXT YEAR.

2370
01:33:17,400 --> 01:33:23,880
AND I KNOW THAT IT'S CHALLENGING

2371
01:33:23,880 --> 01:33:26,080
TO DEVELOP PROGRAMS THAT DON'T

2372
01:33:26,080 --> 01:33:27,720
EXTEND PAST THAT ONE YEAR.

2373
01:33:27,720 --> 01:33:29,480
SO THAT CREATES SOME CHALLENGES

2374
01:33:29,480 --> 01:33:31,000
WITH ONGOING FUNDING NEEDS.

2375
01:33:31,000 --> 01:33:32,560
HOW WILL YOU SPEND ALL THAT

2376
01:33:32,560 --> 01:33:37,760
MONEY IN ONE YEAR?

2377
01:33:37,760 --> 01:33:38,800
>> THANKS, DEB.

2378
01:33:38,800 --> 01:33:40,080
I GLOSSED OVER THAT.

2379
01:33:40,080 --> 01:33:45,360
NOT TO GET IN THE BUDGETARY

2380
01:33:45,360 --> 01:33:46,000
WEEDS TYPICALLY APPROPRIATIONS

2381
01:33:46,000 --> 01:33:48,080
MADE YEAR TO YEAR HAVE TO BE

2382
01:33:48,080 --> 01:33:54,640
SPENT IN EACH YEAR. 

2383
01:33:54,640 --> 01:33:56,720
THE CURES ACT ARE NO-YEAR MONEY,

2384
01:33:56,720 --> 01:33:58,760
ALLOWS US TO CARRY FUNDS IN THIS

2385
01:33:58,760 --> 01:34:00,760
FISCAL FORWARD TO THE NEXT ONE.

2386
01:34:00,760 --> 01:34:02,720
SO WHAT WE BY DESIGN HAVE BEEN

2387
01:34:02,720 --> 01:34:05,120
DOING, WHAT OTHER CURES ACT

2388
01:34:05,120 --> 01:34:06,480
FUNDED PROGRAMS ARE DOING, WE'RE

2389
01:34:06,480 --> 01:34:08,200
LOOKING FURTHER AHEAD INTO THE

2390
01:34:08,200 --> 01:34:08,520
FUTURE.

2391
01:34:08,520 --> 01:34:11,160
AS I THINK THE FOLKS HERE OF

2392
01:34:11,160 --> 01:34:14,360
COURSE KNOW, WHEN WE FUND A

2393
01:34:14,360 --> 01:34:16,520
PROJECT, THERE ARE OUT-YEAR

2394
01:34:16,520 --> 01:34:16,960
COMMITMENTS.

2395
01:34:16,960 --> 01:34:18,240
THREE-YEAR PROJECT OR FIVE-YEAR

2396
01:34:18,240 --> 01:34:19,360
PROJECT, WHATEVER.

2397
01:34:19,360 --> 01:34:25,240
WE CAN USE THE  FUNDS TO SMOOTH

2398
01:34:25,240 --> 01:34:30,440
OUT THE BACK END OF THE CURVE

2399
01:34:30,440 --> 01:34:33,200
ABOUT TWO-THIRDS OF OUR FUNDS GO

2400
01:34:33,200 --> 01:34:35,120
TOWARD SUPPORTING THESE OUT-YEAR

2401
01:34:35,120 --> 01:34:36,480
COMMITMENTS, CURRENT

2402
01:34:36,480 --> 01:34:36,760
COMMITMENTS.

2403
01:34:36,760 --> 01:34:39,520
AND THE BEAUTY OF THE CURES ACT

2404
01:34:39,520 --> 01:34:41,000
FUND ALLOWS US TO SMOOTH OUT

2405
01:34:41,000 --> 01:34:43,120
BACK END OF THE CURVE,

2406
01:34:43,120 --> 01:34:45,440
ESPECIALLY SINCE WE HAVE THIS

2407
01:34:45,440 --> 01:34:47,160
GIGANTIC BUMP IN FY23, THIS

2408
01:34:47,160 --> 01:34:49,160
ALLOWS US TO MAINTAIN A PRETTY

2409
01:34:49,160 --> 01:34:50,920
STEADY LEVEL OF FUNDING THAT'S

2410
01:34:50,920 --> 01:34:55,960
ACTUALLY  ABOVE BASE ALLOCATION,

2411
01:34:55,960 --> 01:34:58,720
THAT'S OUR STRATEGY FOR USING

2412
01:34:58,720 --> 01:34:59,960
THESE FUNDS.

2413
01:34:59,960 --> 01:35:02,240
A QUESTION FROM BEN.

2414
01:35:02,240 --> 01:35:02,760
>> HI.

2415
01:35:02,760 --> 01:35:04,920
WELCOME FROM THE OLFACTORY SIDE.

2416
01:35:04,920 --> 01:35:06,960
GREAT TO SEE YOU AND STUDIES YOU

2417
01:35:06,960 --> 01:35:08,080
HIGHLIGHTED FROM THE BRAIN

2418
01:35:08,080 --> 01:35:10,200
INITIATIVE I THINK ARE ACTIVIC

2419
01:35:10,200 --> 01:35:11,160
TOO.

2420
01:35:11,160 --> 01:35:13,160
THANKS FOR HIGHLIGHTING THOSE.

2421
01:35:13,160 --> 01:35:16,240
SO, I WANTED TO GET YOUR

2422
01:35:16,240 --> 01:35:19,160
PERSPECTIVE ON HOW YOU SEE THE

2423
01:35:19,160 --> 01:35:20,480
BRAIN INITIATIVE FUNDING

2424
01:35:20,480 --> 01:35:22,760
CONNECTING TO MAINSTREAM NIH

2425
01:35:22,760 --> 01:35:23,360
FUNDING.

2426
01:35:23,360 --> 01:35:25,080
I KNOW I TALKED TO SOME PEOPLE

2427
01:35:25,080 --> 01:35:27,600
ON THE ORIGINAL PANEL WHEN THEY

2428
01:35:27,600 --> 01:35:29,560
WERE FORMULATING THIS, AND I WAS

2429
01:35:29,560 --> 01:35:31,000
SAYING, WELL, WHAT HAPPENS IF

2430
01:35:31,000 --> 01:35:33,200
THE BRAIN INITIATIVE BECOMES SO

2431
01:35:33,200 --> 01:35:35,720
SUCCESSFUL IT DRAWS SO MANY

2432
01:35:35,720 --> 01:35:38,560
PEOPLE AWAY FROM CLASSIC

2433
01:35:38,560 --> 01:35:41,080
CELLULAR MECHANISTIC QUESTIONS.

2434
01:35:41,080 --> 01:35:42,640
AND THEY WERE EXPLICIT, THEY SEE

2435
01:35:42,640 --> 01:35:45,920
THIS BRAIN INITIATIVE AS

2436
01:35:45,920 --> 01:35:47,120
CREATING SEPARATE FUNDING,

2437
01:35:47,120 --> 01:35:51,280
EXPANDING THE POOL, BUT IT HAS

2438
01:35:51,280 --> 01:35:52,800
HAD THIS EFFECT OF DRAWING SO

2439
01:35:52,800 --> 01:35:54,440
MANY PEOPLE AWAY THAT LIKE THE

2440
01:35:54,440 --> 01:35:55,960
CLASSIC METHODS THAT ARE STILL

2441
01:35:55,960 --> 01:36:00,160
GOING TO BE IMPORTANT FOR A LONG

2442
01:36:00,160 --> 01:36:05,200
TIME VERY FEW LABS ARE DOING 

2443
01:36:05,200 --> 01:36:06,400
THEM ANYMORE, WRITING DOWN

2444
01:36:06,400 --> 01:36:08,040
PAIRED RECORDING BEFORE THE LAST

2445
01:36:08,040 --> 01:36:08,800
PERSON IS GONE.

2446
01:36:08,800 --> 01:36:12,280
DO YOU STILL SEE THIS AS SORT

2447
01:36:12,280 --> 01:36:15,600
OF, YOU KNOW, THIS SEPARATE

2448
01:36:15,600 --> 01:36:20,160
MISSION THAT'S A WAKE BEHAVING

2449
01:36:20,160 --> 01:36:21,360
ANIMAL FOCUSED AND CORE NIH

2450
01:36:21,360 --> 01:36:24,040
PROBLEM OR SORT OF CONNECTED

2451
01:36:24,040 --> 01:36:24,320
SOMEHOW?

2452
01:36:24,320 --> 01:36:27,160
IS YOUR FUTURE SOMEHOW CONNECTED

2453
01:36:27,160 --> 01:36:29,520
TO STUFF TRADITIONALLY FUNDED BY

2454
01:36:29,520 --> 01:36:30,160
NON-BRAIN NIH STUFF?

2455
01:36:30,160 --> 01:36:31,640
>> RIGHT.

2456
01:36:31,640 --> 01:36:37,600
THAT'S A GREAT QUESTION, BEN. 

2457
01:36:37,600 --> 01:36:40,240
I THINK THE -- THIS IS GOING TO

2458
01:36:40,240 --> 01:36:42,240
REQUIRE, YOU KNOW, MUCH LONGER

2459
01:36:42,240 --> 01:36:44,240
CONVERSATION TO GET AT IN

2460
01:36:44,240 --> 01:36:44,600
DETAIL.

2461
01:36:44,600 --> 01:36:46,680
MY SHORT TAKE ON THIS IS IT IS

2462
01:36:46,680 --> 01:36:47,880
SOMETHING WE'RE CONCERNED ABOUT.

2463
01:36:47,880 --> 01:36:49,920
NOW, IN THE TALKS I'VE BEEN

2464
01:36:49,920 --> 01:36:51,480
GIVING RECENTLY, I'VE BEEN

2465
01:36:51,480 --> 01:36:53,520
FOCUSING ON BIG PROJECTS BUT

2466
01:36:53,520 --> 01:36:55,400
REALLY THESE BIG PROJECTS AS

2467
01:36:55,400 --> 01:36:57,360
WELL AS OTHER SMALLER

2468
01:36:57,360 --> 01:36:58,440
TECHNOLOGY-DRIVEN PROJECTS ARE

2469
01:36:58,440 --> 01:37:00,320
DESIGNED TO ENABLE US TO DO

2470
01:37:00,320 --> 01:37:01,640
BETTER EXPERIMENTS.

2471
01:37:01,640 --> 01:37:03,720
WE JUST NEED BETTER TOOLS TO ASK

2472
01:37:03,720 --> 01:37:05,560
BETTER QUESTIONS.

2473
01:37:05,560 --> 01:37:08,600
AND IN FACT IN THE 2025 REPORT

2474
01:37:08,600 --> 01:37:10,280
THE RECOMMENDATION WAS TO

2475
01:37:10,280 --> 01:37:11,240
SPEND -- WELL, BACK THEN THEY

2476
01:37:11,240 --> 01:37:13,240
WERE SAYING IT WAS A TEN-YEAR

2477
01:37:13,240 --> 01:37:15,080
VISION, RECOMMENDATION THERE WAS

2478
01:37:15,080 --> 01:37:17,040
TO SPEND FIRST HALF DEVELOPING

2479
01:37:17,040 --> 01:37:19,480
TOOLS AND SECOND HALF TO APPLY

2480
01:37:19,480 --> 01:37:21,960
THEM TO UNDERSTAND HOW NEURAL

2481
01:37:21,960 --> 01:37:22,960
CIRCUITS WORK.

2482
01:37:22,960 --> 01:37:25,800
NOW, YOU RAISE A REALLY

2483
01:37:25,800 --> 01:37:28,320
IMPORTANT QUESTION ABOUT THIS

2484
01:37:28,320 --> 01:37:30,160
CONCERN OF THE LOST ARTS.

2485
01:37:30,160 --> 01:37:32,240
I WOULD ARGUE LOOKING BACK I

2486
01:37:32,240 --> 01:37:34,200
THINK EVERY GENERATION OF

2487
01:37:34,200 --> 01:37:37,200
SCIENCE HAS WORRIED ABOUT THE

2488
01:37:37,200 --> 01:37:38,480
PREVIOUS GENERATION'S LOST ART.

2489
01:37:38,480 --> 01:37:40,080
WHAT IS THE NEXT GENERATION

2490
01:37:40,080 --> 01:37:42,560
GOING TO FOR GET THEY NEED TO

2491
01:37:42,560 --> 01:37:44,080
KNOW TO REALLY ASK -- CONTINUE

2492
01:37:44,080 --> 01:37:46,280
ASKING GOOD QUESTIONS?

2493
01:37:46,280 --> 01:37:47,680
IT'S A FAIR CONCERN.

2494
01:37:47,680 --> 01:37:49,880
TO THE EXTENT BRAIN IS A

2495
01:37:49,880 --> 01:37:52,120
REFLECTION OF THAT GOING ON IN

2496
01:37:52,120 --> 01:37:54,680
THE FIELD, OR TO THE EXTENT

2497
01:37:54,680 --> 01:37:56,440
BRAIN IS EITHER CONTRIBUTING TO

2498
01:37:56,440 --> 01:37:57,760
OR EXACERBATING THAT ISSUE I

2499
01:37:57,760 --> 01:38:00,920
CAN'T REALLY SAY BUT, AGAIN, OUR

2500
01:38:00,920 --> 01:38:03,440
FOCUS IS ON ENABLING RESEARCHERS

2501
01:38:03,440 --> 01:38:04,960
TO DO EXPERIMENTS THAT THEY

2502
01:38:04,960 --> 01:38:08,520
COULDN'T DO BEFORE, AND IN FACT

2503
01:38:08,520 --> 01:38:11,200
A VERY LARGE FRACTION OF THE

2504
01:38:11,200 --> 01:38:13,400
BRAIN PORTFOLIO IS FOCUSED ON

2505
01:38:13,400 --> 01:38:14,000
UNDERSTANDING NEURAL CIRCUIT

2506
01:38:14,000 --> 01:38:15,360
FUNCTION, WHAT I CALL THE

2507
01:38:15,360 --> 01:38:22,160
CIRCUIT BUSTING PART OF A

2508
01:38:22,160 --> 01:38:23,440
PORTFOLIO.

2509
01:38:23,440 --> 01:38:25,360
AND I THINK WORKING CLOSELY, THE

2510
01:38:25,360 --> 01:38:26,560
TEAM IS FOCUSED ON THAT.

2511
01:38:26,560 --> 01:38:28,520
THERE WILL BE GIVE AND TAKE.

2512
01:38:28,520 --> 01:38:30,480
THE KEY THING WE AS A SCIENTIFIC

2513
01:38:30,480 --> 01:38:33,120
COMMUNITY MAKE SURE THAT OUR

2514
01:38:33,120 --> 01:38:34,440
STUDENTS AND POSTDOCS AND JUNIOR

2515
01:38:34,440 --> 01:38:35,720
FACULTY KEEP THEIR EYES ON

2516
01:38:35,720 --> 01:38:37,640
WHAT'S GOING TO BE FUNDAMENTALLY

2517
01:38:37,640 --> 01:38:39,080
IMPORTANT AND MAKE SURE THEY ARE

2518
01:38:39,080 --> 01:38:40,480
ASKING THE RIGHT QUESTIONS.

2519
01:38:40,480 --> 01:38:42,440
I THINK BRAIN'S ROLE IS TO HELP

2520
01:38:42,440 --> 01:38:44,160
DEVELOP TOOLS TO MAKE THE TOOLS

2521
01:38:44,160 --> 01:38:47,400
AVAILABLE IN ORDER TO DO THOSE

2522
01:38:47,400 --> 01:38:47,800
STUDIES.

2523
01:38:47,800 --> 01:38:50,080
SO LOVE TO CONTINUE THIS

2524
01:38:50,080 --> 01:38:52,000
DISCUSSION PERHAPS IN PERSON AT

2525
01:38:52,000 --> 01:38:55,880
A LATER DATE.

2526
01:38:55,880 --> 01:38:58,440
>> THANK YOU.

2527
01:38:58,440 --> 01:38:58,840
NIRUPA?

2528
01:38:58,840 --> 01:39:02,680
>> HOW HAVE YOU  ARE YOU?

2529
01:39:02,680 --> 01:39:04,240
LONG TIME.

2530
01:39:04,240 --> 01:39:05,000
AND YOU'RE MUTED.

2531
01:39:05,000 --> 01:39:07,960
>> OH DEAR.

2532
01:39:07,960 --> 01:39:09,360
SORRY.

2533
01:39:09,360 --> 01:39:09,600
OKAY.

2534
01:39:09,600 --> 01:39:11,920
SO, ACTUALLY BEN'S POINT IS

2535
01:39:11,920 --> 01:39:14,320
SOMETHING THAT IS ENDLESSLY

2536
01:39:14,320 --> 01:39:16,720
DISCUSSED, RIGHT?

2537
01:39:16,720 --> 01:39:22,400
YOU KNOW, OVER DRINKS AT EVERY

2538
01:39:22,400 --> 01:39:22,800
CONFERENCE.

2539
01:39:22,800 --> 01:39:24,600
AND I'M WONDERING IF BRAIN

2540
01:39:24,600 --> 01:39:28,520
ACTUALLY HAS COME UP WITH A WAY

2541
01:39:28,520 --> 01:39:31,880
OF TRACKING WHERE -- SO ARE

2542
01:39:31,880 --> 01:39:33,040
THERE MORE REGULAR TRADITIONAL

2543
01:39:33,040 --> 01:39:34,520
R01s THAT ARE SPINOFFS FROM

2544
01:39:34,520 --> 01:39:36,720
THE SAME LAB?

2545
01:39:36,720 --> 01:39:39,680
AND CAN YOU TRACK THAT SOME OR

2546
01:39:39,680 --> 01:39:41,640
ALL OF THAT CAME FROM

2547
01:39:41,640 --> 01:39:48,640
BRAIN-FUNNED WORK --

2548
01:39:48,640 --> 01:39:50,760
BRAIN-FUNDED WORK?

2549
01:39:50,760 --> 01:39:54,360
ALSO CAN YOU TRACK UTILIZATION 

2550
01:39:54,360 --> 01:39:56,640
OF THE BRAIN DERIVED

2551
01:39:56,640 --> 01:39:58,400
TECHNOLOGIES, AND SO WHILE I

2552
01:39:58,400 --> 01:39:59,880
DON'T DISAGREE WITH BEN ON THIS,

2553
01:39:59,880 --> 01:40:03,240
I THINK THAT THERE ARE ACTUALLY

2554
01:40:03,240 --> 01:40:04,520
METRICS THAT YOU CAN USE TO SAY

2555
01:40:04,520 --> 01:40:09,240
HOW BAD IS THE PROBLEM. 

2556
01:40:09,240 --> 01:40:09,720
>> ABSOLUTELY.

2557
01:40:09,720 --> 01:40:10,320
GREAT POINT.

2558
01:40:10,320 --> 01:40:12,520
WE ALWAYS TRY TO REMIND

2559
01:40:12,520 --> 01:40:14,280
OURSELVES OUR DECISIONS TO THE

2560
01:40:14,280 --> 01:40:16,920
EXTENT POSSIBLE NEED TO BE DATA

2561
01:40:16,920 --> 01:40:17,120
DRIVEN.

2562
01:40:17,120 --> 01:40:19,080
THE QUESTION IS WHAT DATA CAN WE

2563
01:40:19,080 --> 01:40:24,000
USE TO HELP DRIVE THESE

2564
01:40:24,000 --> 01:40:24,560
DECISIONS?

2565
01:40:24,560 --> 01:40:25,440
YOUR QUESTION IS BOTH ON THE

2566
01:40:25,440 --> 01:40:27,080
MONEY AS WELL AS TIMELY.

2567
01:40:27,080 --> 01:40:28,480
RIGHT NOW WE'RE WORKING ON

2568
01:40:28,480 --> 01:40:32,400
TRYING TO FIGURE OUT HOW TO --

2569
01:40:32,400 --> 01:40:34,400
WHAT METRICS TO USE, HOW TO

2570
01:40:34,400 --> 01:40:36,640
MEASURE AN INTERPRET THEM TO

2571
01:40:36,640 --> 01:40:38,400
UNDERSTAND WHAT THE IMPACT OF

2572
01:40:38,400 --> 01:40:39,560
BRAIN IS HAVING, RIGHT?

2573
01:40:39,560 --> 01:40:41,200
WE CAN ALL POINT TO A COOL PAPER

2574
01:40:41,200 --> 01:40:42,720
THAT JUST CAME OUT AND SAY THIS

2575
01:40:42,720 --> 01:40:45,360
IS EVIDENCE WE'RE DOING WELL BUT

2576
01:40:45,360 --> 01:40:48,440
THAT'S BEING HIGHLY SUBJECTIVE

2577
01:40:48,440 --> 01:40:50,080
AND HIGHLY SELECTIVE.

2578
01:40:50,080 --> 01:40:52,040
WE HAD THIS COOL -- THERE WAS A

2579
01:40:52,040 --> 01:40:54,440
COOL PROGRAM, THERE IS A COOL

2580
01:40:54,440 --> 01:40:56,160
PROGRAM AT NIH BRINGING IN DATA

2581
01:40:56,160 --> 01:40:57,520
SCHOLARS AND BRAIN WAS FORTUNATE

2582
01:40:57,520 --> 01:41:00,920
TO PARTICIPATE IN THIS PROGRAM.

2583
01:41:00,920 --> 01:41:05,520
AND WE STARTED THIS BRAIN WORKS

2584
01:41:05,520 --> 01:41:08,120
WHETHER OUR DATA SCHOLAR DR.

2585
01:41:08,120 --> 01:41:11,760
GASIMI FROM MICHIGAN STATE USED 

2586
01:41:11,760 --> 01:41:13,720
NATURAL LANGUAGE PROCESSING

2587
01:41:13,720 --> 01:41:14,960
ALGORITHMS TO HELP IDENTIFY

2588
01:41:14,960 --> 01:41:16,480
CONNECTIONS, SO IT'S A WORK IN

2589
01:41:16,480 --> 01:41:18,320
PROGRESS BUT WE THINK THESE

2590
01:41:18,320 --> 01:41:20,120
EFFORTS AND OTHER EFFORTS BEING

2591
01:41:20,120 --> 01:41:22,360
DONE BY INFORMATION SCIENTISTS

2592
01:41:22,360 --> 01:41:24,480
MIGHT HELP US UNDERSTAND WHAT

2593
01:41:24,480 --> 01:41:26,440
ARE THE CONNECTIONS BETWEEN

2594
01:41:26,440 --> 01:41:27,960
THESE DIFFERENT -- NOT JUST

2595
01:41:27,960 --> 01:41:28,960
DIFFERENT PROJECTS BUT DIFFERENT

2596
01:41:28,960 --> 01:41:30,480
KINDS OF PROJECTS AND WHAT MIGHT

2597
01:41:30,480 --> 01:41:32,680
BE THE IMPACT AND REALLY WE'RE

2598
01:41:32,680 --> 01:41:34,800
APPROACHING THIS AS NOT UNLIKE

2599
01:41:34,800 --> 01:41:38,160
THE WAY THAT I HAVE APPROACHED

2600
01:41:38,160 --> 01:41:40,360
SINGLE CELL BIOLOGY WHICH IS

2601
01:41:40,360 --> 01:41:42,320
LET'S KIND OF GET A GOOD FEELING

2602
01:41:42,320 --> 01:41:43,640
FOR WHAT'S GOING ON OUT THERE

2603
01:41:43,640 --> 01:41:46,280
AND SEE WHAT KIND OF HYPOTHESES

2604
01:41:46,280 --> 01:41:48,560
MIGHT EMERGE THAT WE CAN THEN GO

2605
01:41:48,560 --> 01:41:50,080
ON AND TEST.

2606
01:41:50,080 --> 01:41:51,280
SO WE'RE LOOKING AT THIS AND

2607
01:41:51,280 --> 01:41:53,520
IT'S VERY IMPORTANT FOR US TO

2608
01:41:53,520 --> 01:41:55,920
UNDERSTAND THAT.

2609
01:41:55,920 --> 01:41:56,320
>> THANKS.

2610
01:41:56,320 --> 01:41:58,400
>> THANK YOU.

2611
01:41:58,400 --> 01:41:58,720
MEG WALLHAGEN?

2612
01:41:58,720 --> 01:42:01,520
>> THANK YOU VERY MUCH FOR
YOUR

2613
01:42:01,520 --> 01:42:02,240
PRESENTATION.

2614
01:42:02,240 --> 01:42:04,880
I'M NOT SURE HOW TO BEST

2615
01:42:04,880 --> 01:42:05,720
ARTICULATE THIS BUT I'M

2616
01:42:05,720 --> 01:42:09,360
INTERESTED IN SOME OF THE

2617
01:42:09,360 --> 01:42:10,480
TRANSLATIONAL ISSUES, WHETHER

2618
01:42:10,480 --> 01:42:11,800
YOU'VE ALREADY THOUGHT ABOUT --

2619
01:42:11,800 --> 01:42:13,840
SOME OF WHAT YOU PRESENTED DID

2620
01:42:13,840 --> 01:42:15,760
SHOW SOME OF THAT BEGINNING

2621
01:42:15,760 --> 01:42:17,240
TRANSLATION IN TERMS OF THE

2622
01:42:17,240 --> 01:42:19,480
SPEECH AND SO FORTH, BUT HOW ARE

2623
01:42:19,480 --> 01:42:23,480
YOU ABLE TO LOOK AT THE

2624
01:42:23,480 --> 01:42:25,040
CROSS-MODALITY EXPERIENTIAL

2625
01:42:25,040 --> 01:42:26,560
ASPECT SOME CONNECTIONS MAKE, OR

2626
01:42:26,560 --> 01:42:28,640
BEGIN TO ALREADY BUILD IN SOME

2627
01:42:28,640 --> 01:42:31,280
OF THE WAYS IN WHICH THE DATA

2628
01:42:31,280 --> 01:42:33,560
THAT YOU'RE COLLECTING CAN BEGIN

2629
01:42:33,560 --> 01:42:37,280
TO TRANSLATE INTO MORE

2630
01:42:37,280 --> 01:42:38,480
CLINICALLY DERIVED QUESTIONS, SO

2631
01:42:38,480 --> 01:42:42,200
THAT THERE CAN BE QUICK

2632
01:42:42,200 --> 01:42:43,760
TRANSLATION OF YOUR FINDINGS

2633
01:42:43,760 --> 01:42:46,680
INTO MORE CLINICALLY BASED

2634
01:42:46,680 --> 01:42:48,800
PRACTICES, IF THAT IS CLEAR.

2635
01:42:48,800 --> 01:42:50,960
>> YEAH, WELL, LET ME SEE
IF I

2636
01:42:50,960 --> 01:42:52,040
UNDERSTOOD YOUR QUESTION.

2637
01:42:52,040 --> 01:42:56,880
YOU CAN TELL ME AFTER I RESPOND.

2638
01:42:56,880 --> 01:42:59,680
THERE'S AN EMPHASIS ON BOTH

2639
01:42:59,680 --> 01:43:01,600
BASIC DISCOVERY, BUT IN

2640
01:43:01,600 --> 01:43:02,720
TRANSLATION, AND IMPACTS IN

2641
01:43:02,720 --> 01:43:06,440
HUMANS, AND WITH AN EYE TOWARD

2642
01:43:06,440 --> 01:43:06,760
TRANSLATION.

2643
01:43:06,760 --> 01:43:09,280
WE HAVE A WHOLE PROGRAM THAT WE

2644
01:43:09,280 --> 01:43:10,480
REFER TO, RESEARCH OPPORTUNITIES

2645
01:43:10,480 --> 01:43:13,440
IN HUMANS THAT ACTUALLY LOOKS TO

2646
01:43:13,440 --> 01:43:14,960
THE EXTENT POSSIBLE IN HUMANS

2647
01:43:14,960 --> 01:43:16,200
NEURAL CIRCUIT FUNCTION AND

2648
01:43:16,200 --> 01:43:17,480
RELATION TO THE BEHAVIOR.

2649
01:43:17,480 --> 01:43:20,880
IN FACT WE'RE ABOUT TO STEP UP A

2650
01:43:20,880 --> 01:43:26,800
PROGRAM IN LOOKING AT

2651
01:43:26,800 --> 01:43:27,440
SYNCHRONIZING BEHAVIOR AND

2652
01:43:27,440 --> 01:43:28,440
NEURAL ACTIVITY.

2653
01:43:28,440 --> 01:43:29,720
ONE EXAMPLE OF TRANSLATION IS

2654
01:43:29,720 --> 01:43:31,920
COMING OUT OF THE CELL CENSUS

2655
01:43:31,920 --> 01:43:35,680
PROJECT, MAKING A HUGE

2656
01:43:35,680 --> 01:43:38,520
INVESTMENT IN CHARACTERIZING AND

2657
01:43:38,520 --> 01:43:39,920
ORGANIZING CELL TYPES IN

2658
01:43:39,920 --> 01:43:40,560
MAMMALIAN BRAINS.

2659
01:43:40,560 --> 01:43:44,160
ALREADY WE'VE SEEN FROM THE

2660
01:43:44,160 --> 01:43:46,160
BICCN THE IDENTIFICATION OF

2661
01:43:46,160 --> 01:43:48,440
HUMAN-SPECIFIC CELL TYPES THAT

2662
01:43:48,440 --> 01:43:49,080
ARE SELECTIVELY VULNERABLE IN

2663
01:43:49,080 --> 01:43:50,520
ALZHEIMER'S DISEASE.

2664
01:43:50,520 --> 01:43:55,320
THIS IS COMING OUT OF THE ALLEN

2665
01:43:55,320 --> 01:43:55,600
INSTITUTE.

2666
01:43:55,600 --> 01:43:57,520
RECENTLY EVAN McCOSTKO AT THE

2667
01:43:57,520 --> 01:44:01,120
BROAD PUBLISHED A COOL PAPER

2668
01:44:01,120 --> 01:44:02,560
PROFILING USING OMICS

2669
01:44:02,560 --> 01:44:04,000
TECHNOLOGIES, MID-BRAIN DOPAMINE

2670
01:44:04,000 --> 01:44:07,360
NEURONS IN HUMANS AND HUMANS

2671
01:44:07,360 --> 01:44:11,960
WITH PARKINSON'S DISEASE, 

2672
01:44:11,960 --> 01:44:15,360
IDENTIFIED SUBSET OF THESE

2673
01:44:15,360 --> 01:44:18,000
NEURONS THAT MAPPED SECTIONS OF

2674
01:44:18,000 --> 01:44:19,400
THE SUBSTANTIALLY NIGRA IN P.D.

2675
01:44:19,400 --> 01:44:20,760
PATIENTS, AND THESE CELLS ARE

2676
01:44:20,760 --> 01:44:23,480
ONES THAT EXPRESS GENES THAT

2677
01:44:23,480 --> 01:44:27,120
HAVE BEEN IDENTIFIED IN GWAS

2678
01:44:27,120 --> 01:44:27,360
STUDIES.

2679
01:44:27,360 --> 01:44:28,960
NOW WE HAVE MUCH GREATER

2680
01:44:28,960 --> 01:44:30,400
GRANULARITY OF WHAT CELLS ARE

2681
01:44:30,400 --> 01:44:33,040
AFFECTED AND OF IN VARIOUS

2682
01:44:33,040 --> 01:44:33,880
NEURODEGENERATIVE DISEASES, THIS

2683
01:44:33,880 --> 01:44:35,320
IS ONE EXAMPLE.

2684
01:44:35,320 --> 01:44:36,200
AND WITH THE ARMAMENTARIUM

2685
01:44:36,200 --> 01:44:38,600
PROJECT WE NOW HAVE THE

2686
01:44:38,600 --> 01:44:39,640
OPPORTUNITY TO START MODELING

2687
01:44:39,640 --> 01:44:42,520
THIS IN ANIMAL MODELS AND

2688
01:44:42,520 --> 01:44:44,840
EVENTUALLY WE HOPE TO UNDERSTAND

2689
01:44:44,840 --> 01:44:46,600
BETTER HOW CELLS FUNCTION, WHY

2690
01:44:46,600 --> 01:44:47,800
ARE THEY BEING AFFECTED,

2691
01:44:47,800 --> 01:44:50,160
ULTIMATELY TO HOPEFULLY GO IN

2692
01:44:50,160 --> 01:44:51,760
AND INTERVENE.

2693
01:44:51,760 --> 01:44:55,000
I THINK THERE'S JUST THE

2694
01:44:55,000 --> 01:44:57,760
POSSIBILITIES ARE ENDLESS, WE

2695
01:44:57,760 --> 01:44:59,600
HAVE TO BE FOCUSED ON WHERE TO

2696
01:44:59,600 --> 01:45:00,720
LOOK AND LEVERAGE THIS

2697
01:45:00,720 --> 01:45:01,280
INFORMATION.

2698
01:45:01,280 --> 01:45:03,360
I HOPE THAT ANSWERS AT LEAST

2699
01:45:03,360 --> 01:45:05,360
PART OF YOUR QUESTION.

2700
01:45:05,360 --> 01:45:05,800
>> VERY HELPFUL.

2701
01:45:05,800 --> 01:45:06,160
THANK YOU.

2702
01:45:06,160 --> 01:45:10,120
>> I THOUGHT I WOULD GIVE
THE

2703
01:45:10,120 --> 01:45:12,200
LAST WORD TO DAN, OUR

2704
01:45:12,200 --> 01:45:13,920
REPRESENTATIVE TO THE

2705
01:45:13,920 --> 01:45:15,560
MULTI-COUNCIL WORKING GROUP OF

2706
01:45:15,560 --> 01:45:16,120
BRAIN.

2707
01:45:16,120 --> 01:45:19,640
AND THANK YOU, DAN, FOR

2708
01:45:19,640 --> 01:45:21,480
REPRESENTING NIDCD.

2709
01:45:21,480 --> 01:45:22,480
>> THANKS, DEB.

2710
01:45:22,480 --> 01:45:29,280
I WANT TO THANK JOHN FOR A

2711
01:45:29,280 --> 01:45:30,720
TREMENDOUS PRESENTATION, OPEN TO

2712
01:45:30,720 --> 01:45:32,160
BEING CONTACTED AND QUERIED

2713
01:45:32,160 --> 01:45:33,040
ABOUT IT.

2714
01:45:33,040 --> 01:45:35,320
I WOULD URGE YOU IF YOU HAVE

2715
01:45:35,320 --> 01:45:36,640
QUESTIONS TO CONTACT JOHN OR

2716
01:45:36,640 --> 01:45:37,640
PROGRAM OFFICERS THERE.

2717
01:45:37,640 --> 01:45:40,680
I JUST WANT TO BRIEFLY EMPHASIZE

2718
01:45:40,680 --> 01:45:48,360
A COUPLE THINGS. 

2719
01:45:48,360 --> 01:45:53,280
FIRST, WE, ROB AND AMY AND

2720
01:45:53,280 --> 01:45:57,680
MARIA, ORGANIZED AN ONLINE

2721
01:45:57,680 --> 01:45:59,080
ESSENTIALLY INFORMATIONAL

2722
01:45:59,080 --> 01:46:03,240
SESSION THAT WAS SPONSORED BY

2723
01:46:03,240 --> 01:46:08,640
MARIA GEFFIN'S SEMINAR SERIES IN

2724
01:46:08,640 --> 01:46:10,720
WHICH THE TITLE WAS

2725
01:46:10,720 --> 01:46:12,040
DEMYSTIFYING, AND I WOULD URGE

2726
01:46:12,040 --> 01:46:14,760
YOU TO HAVE A LOOK AT THAT IF

2727
01:46:14,760 --> 01:46:20,160
YOU HAVE ANY QUESTIONS AT ALL.

2728
01:46:20,160 --> 01:46:21,880
I'M PUTTING IT IN THE CHAT,

2729
01:46:21,880 --> 01:46:24,880
LINKS TO THAT TALK ARE AVAILABLE

2730
01:46:24,880 --> 01:46:25,400
TO YOU.

2731
01:46:25,400 --> 01:46:27,480
I THINK THAT WILL ANSWER A LOT

2732
01:46:27,480 --> 01:46:28,600
OF PEOPLE'S SPECIFIC QUESTIONS

2733
01:46:28,600 --> 01:46:36,160
ABOUT   GETTING INVOLVED IN THE

2734
01:46:36,160 --> 01:46:37,000
BRAIN INITIATIVE.

2735
01:46:37,000 --> 01:46:38,560
SECOND POINT JOHN DIDN'T COVER

2736
01:46:38,560 --> 01:46:40,320
BUT I WANTED TO EMPHASIZE IS

2737
01:46:40,320 --> 01:46:43,920
THAT THE BRAIN INITIATIVE IS

2738
01:46:43,920 --> 01:46:45,640
CONSTANTLY COMING UP WITH,

2739
01:46:45,640 --> 01:46:47,080
EXAMINING, DISCUSSING NEW

2740
01:46:47,080 --> 01:46:49,720
INITIATIVES AND CONCEPTS, AND

2741
01:46:49,720 --> 01:46:52,160
I'M GOING TO PUT ONE OF THOSE

2742
01:46:52,160 --> 01:46:54,960
ALSO IN THE CHAT.

2743
01:46:54,960 --> 01:46:55,840
THEY ARE CURRENTLY CONSIDERING

2744
01:46:55,840 --> 01:46:58,120
ESSENTIALLY SOMETHING CALLED THE

2745
01:46:58,120 --> 01:46:59,840
BRAIN BEHAVIOR QUANTIFICATION

2746
01:46:59,840 --> 01:47:00,680
AND SYNCHRONIZATION INITIATIVE,

2747
01:47:00,680 --> 01:47:03,080
AND THESE ARE CONCEPTS THAT ARE

2748
01:47:03,080 --> 01:47:04,760
AIMED AT DEVELOPING NEW HIGH

2749
01:47:04,760 --> 01:47:06,800
RESOLUTION TOOLS AND DATA

2750
01:47:06,800 --> 01:47:08,800
SCIENCE APPROACHES TO PRECISELY

2751
01:47:08,800 --> 01:47:10,320
QUANTIFY BEHAVIORS AND

2752
01:47:10,320 --> 01:47:11,200
SYNCHRONIZE THEM WITH BRAIN

2753
01:47:11,200 --> 01:47:12,480
ACTIVITY DATA.

2754
01:47:12,480 --> 01:47:13,440
SO JOHN EMPHASIZED BRAIN DATA

2755
01:47:13,440 --> 01:47:15,120
PERIODONTAL SAY BUT OF COURSE IN

2756
01:47:15,120 --> 01:47:17,760
THE LONG RUN PHENOTYPE IS

2757
01:47:17,760 --> 01:47:19,000
BEHAVIOR, WHETHER NORMAL

2758
01:47:19,000 --> 01:47:19,920
BEHAVIOR OR ABNORMAL BEHAVIOR.

2759
01:47:19,920 --> 01:47:22,120
I FIND THESE KINDS OF

2760
01:47:22,120 --> 01:47:25,200
INITIATIVES TO BE EXTREMELY

2761
01:47:25,200 --> 01:47:26,320
EXCITING, AND PROBABLY BROADEN

2762
01:47:26,320 --> 01:47:29,120
INITIATIVE TO A LARGE NUMBER OF

2763
01:47:29,120 --> 01:47:31,400
PEOPLE WHO ARE PRIMARILY

2764
01:47:31,400 --> 01:47:34,280
INTERESTED IN BEHAVIORAL

2765
01:47:34,280 --> 01:47:35,160
PHENOTYPES OR DYSFUNCTION.

2766
01:47:35,160 --> 01:47:36,120
I'LL PUT THAT IN THE CHAT AND

2767
01:47:36,120 --> 01:47:37,880
YOU CAN HAVE A LOOK AT THAT

2768
01:47:37,880 --> 01:47:39,080
PARTICULAR INITIATIVE.

2769
01:47:39,080 --> 01:47:42,400
THAT'S ALL I HAD FOR YOU.

2770
01:47:42,400 --> 01:47:43,040
>> THANKS, DAN.

2771
01:47:43,040 --> 01:47:44,800
I HOPE EVERYBODY CAN SEE WHY

2772
01:47:44,800 --> 01:47:47,440
IT'S OF I APPRECIATE DAN'S

2773
01:47:47,440 --> 01:47:50,120
PARTICIPATION IN "BRAIN" AS A

2774
01:47:50,120 --> 01:47:51,520
REPRESENTATIVE OF NIDCD ON THE

2775
01:47:51,520 --> 01:47:53,960
MULTI-COUNCIL WORKING GROUP.

2776
01:47:53,960 --> 01:47:54,400
THANKS AGAIN.

2777
01:47:54,400 --> 01:47:55,440
>> THANK YOU.

2778
01:47:55,440 --> 01:47:55,720
>> GREAT.

2779
01:47:55,720 --> 01:47:58,120
WELL, THANK YOU ALL.

2780
01:47:58,120 --> 01:48:03,800
WE'LL TURN TO AMY AND MERAV NOW

2781
01:48:03,800 --> 01:48:06,480
TO LEAD THE REST OF THE PROGRAM.

2782
01:48:06,480 --> 01:48:07,560
>> THANKS.

2783
01:48:07,560 --> 01:48:08,760
CAN EVERYONE HEAR ME?

2784
01:48:08,760 --> 01:48:10,560
THANK YOU.

2785
01:48:10,560 --> 01:48:14,200
GOOD MORNING.

2786
01:48:14,200 --> 01:48:16,280
I'M AMY POREMBA, PROGRAM

2787
01:48:16,280 --> 01:48:17,800
DIRECTOR, I A REPRESENTATIVE WHO

2788
01:48:17,800 --> 01:48:19,000
WORKS WITH THE BRAIN INITIATIVE

2789
01:48:19,000 --> 01:48:20,080
FORTUNE OUR INSTITUTE.

2790
01:48:20,080 --> 01:48:21,440
I WANT TO SAY THANK YOU TO DR.

2791
01:48:21,440 --> 01:48:25,240
JOHN NGAI FOR COMING TO UPDATE 

2792
01:48:25,240 --> 01:48:28,040
US ON THE PROGRESS AS DIRECTOR,

2793
01:48:28,040 --> 01:48:30,680
AND AS YOU HEARD THE BRAIN

2794
01:48:30,680 --> 01:48:33,520
INITIATIVE IS VERY LARGE

2795
01:48:33,520 --> 01:48:35,160
NIH-WIDE PROGRAM, WILL PROVIDE

2796
01:48:35,160 --> 01:48:37,520
OVER $5 BILLION IN NEUROSCIENCE

2797
01:48:37,520 --> 01:48:41,360
FUNDING BY 2026.

2798
01:48:41,360 --> 01:48:42,160
NEXT SLIDE.

2799
01:48:42,160 --> 01:48:44,080
SO OVER 120 PEOPLE AT NIH WORK

2800
01:48:44,080 --> 01:48:45,400
IN SEVERAL CAPACITIES AT JOHN

2801
01:48:45,400 --> 01:48:47,720
MENTIONED TO SUPPORT THE BRAIN

2802
01:48:47,720 --> 01:48:48,080
INITIATIVE.

2803
01:48:48,080 --> 01:48:53,720
MANY ARE VOLUNTEERING OR ON LOAN

2804
01:48:53,720 --> 01:48:56,840
FROM INSTITUTES.

2805
01:48:56,840 --> 01:48:58,440
REPRESENTATIVES ARE MYSELF, DR.

2806
01:48:58,440 --> 01:49:04,880
ROGER MILLER AND DR. RIVERA 

2807
01:49:04,880 --> 01:49:07,880
RENTAS AND OTHERS ON AD HOC

2808
01:49:07,880 --> 01:49:11,480
BASIS LIKE DR. SULLIVAN AND DR.

2809
01:49:11,480 --> 01:49:13,360
SANES, DOUBLE DUTY, AND ON THE

2810
01:49:13,360 --> 01:49:14,480
BRAIN INITIATIVE MULTI-COUNCIL

2811
01:49:14,480 --> 01:49:15,640
WORKING GROUP.

2812
01:49:15,640 --> 01:49:17,320
WE'RE GREATLY APPRECIATIVE OF

2813
01:49:17,320 --> 01:49:21,240
DAN'S REPRESENTATION OF OUR

2814
01:49:21,240 --> 01:49:21,600
INSTITUTE.

2815
01:49:21,600 --> 01:49:24,400
NEXT SLIDE.

2816
01:49:24,400 --> 01:49:25,280
NEXT SLIDE.

2817
01:49:25,280 --> 01:49:26,880
IN ORDER TO PROMOTE INCREASED

2818
01:49:26,880 --> 01:49:29,120
SYNERGY BETWEEN BRAIN INITIATIVE

2819
01:49:29,120 --> 01:49:33,600
AND OUR OWN INSTITUTE, DR. MERAV

2820
01:49:33,600 --> 01:49:38,000
SABRI CAME TO JOIN US THIS PAST

2821
01:49:38,000 --> 01:49:38,560
OCTOBER.

2822
01:49:38,560 --> 01:49:41,720
AREAS OF EXPERTISE IN COGNITIVE

2823
01:49:41,720 --> 01:49:42,520
NEUROSCIENCE, BRAIN IMAGING

2824
01:49:42,520 --> 01:49:43,840
TECHNOLOGY, RECEIVED HER Ph.D.

2825
01:49:43,840 --> 01:49:46,000
AT UNIVERSITY OF OTTAWA IN

2826
01:49:46,000 --> 01:49:46,880
ONTARIO, CANADA.

2827
01:49:46,880 --> 01:49:49,760
PRIOR TO JOINING THE NIH SHE WAS

2828
01:49:49,760 --> 01:49:55,880
ASSISTANT PROFESSOR OF NEURAL

2829
01:49:55,880 --> 01:49:56,840
AND OTOLARYNGOLOGIY IN AT

2830
01:49:56,840 --> 01:49:58,160
UNIVERSITY OF WISCONSIN.

2831
01:49:58,160 --> 01:50:00,360
WE'RE QUITE LUCKY TO HAVE HER ON

2832
01:50:00,360 --> 01:50:01,400
BOARD PROVIDING A STRONG BASE OF

2833
01:50:01,400 --> 01:50:03,280
COMMUNICATION FOR P.I.s ABOUT

2834
01:50:03,280 --> 01:50:04,200
THE BRAIN INITIATIVE.

2835
01:50:04,200 --> 01:50:06,680
I SUGGEST YOU REACH OUT TO HER

2836
01:50:06,680 --> 01:50:07,480
AND THE OTHER REPRESENTATIVES

2837
01:50:07,480 --> 01:50:10,320
AND WE'LL BE HAPPY TO FILL YOU

2838
01:50:10,320 --> 01:50:11,640
IN BUT SHE'S SPENDING A LOT OF

2839
01:50:11,640 --> 01:50:13,400
TIME AND DEDICATED TO HER WORK

2840
01:50:13,400 --> 01:50:14,680
IN THE BRAIN INITIATIVE.

2841
01:50:14,680 --> 01:50:16,520
HER POSITION IS SHARED BETWEEN

2842
01:50:16,520 --> 01:50:22,160
OUR INSTITUTE AND THE BRAIN

2843
01:50:22,160 --> 01:50:27,840
INITIATIVE, 50/ 50, FOCUSING ON

2844
01:50:27,840 --> 01:50:30,120
HIGHER OLFACTORY AND TASTE

2845
01:50:30,120 --> 01:50:30,600
PROCESSING.

2846
01:50:30,600 --> 01:50:31,240
NEXT SLIDE.

2847
01:50:31,240 --> 01:50:35,040
THE BRAIN INITIATIVE IS

2848
01:50:35,040 --> 01:50:37,040
INTERNALLY ORGANIZED IN TEAMS OF

2849
01:50:37,040 --> 01:50:38,040
PROGRAM OFFICERS, SCIENTIFIC

2850
01:50:38,040 --> 01:50:40,080
REVIEW OFFICERS.

2851
01:50:40,080 --> 01:50:42,280
THE TEAMS HELP WRITE FUNDING

2852
01:50:42,280 --> 01:50:44,360
ANNOUNCEMENTS RELATED TO THEIR

2853
01:50:44,360 --> 01:50:47,200
MISSION, ATTEND GRANT REVIEWS,

2854
01:50:47,200 --> 01:50:49,840
SUGGEST FUNDING PLANS,

2855
01:50:49,840 --> 01:50:50,120
VOLUNTEER.

2856
01:50:50,120 --> 01:50:52,360
IT'S A GREAT ENVIRONMENT TO BE

2857
01:50:52,360 --> 01:50:52,560
IN.

2858
01:50:52,560 --> 01:50:53,440
IT'S VERY INTERACTIVE.

2859
01:50:53,440 --> 01:50:56,280
THERE ARE A LOT OF EXCITED

2860
01:50:56,280 --> 01:50:58,920
PEOPLE HELPING TO DO THESE

2861
01:50:58,920 --> 01:50:59,320
ACTIVITIES.

2862
01:50:59,320 --> 01:51:01,400
FUNDING PLANS ARE GENERATED BY

2863
01:51:01,400 --> 01:51:03,320
THE TEAMS, PROGRESS TO

2864
01:51:03,320 --> 01:51:04,640
COORDINATING TEAM, WHICH HAS ONE

2865
01:51:04,640 --> 01:51:06,680
MEMBER FROM EACH I.C. AS A

2866
01:51:06,680 --> 01:51:07,560
PROGRAM OFFICER.

2867
01:51:07,560 --> 01:51:09,320
AND THAT INFORMATION GOES TO THE

2868
01:51:09,320 --> 01:51:10,400
I.C. DIRECTOR'S GROUP WHO TAKES

2869
01:51:10,400 --> 01:51:12,160
ANOTHER BIG LOOK AT IT.

2870
01:51:12,160 --> 01:51:17,760
THE BRAIN INITIATIVE

2871
01:51:17,760 --> 01:51:20,480
MULTI-COUNCIL WORKING GROUP.

2872
01:51:20,480 --> 01:51:21,360
WORK IS INVOLVED IS GETTING

2873
01:51:21,360 --> 01:51:24,320
TOGETHER TO DO THE FUNDING

2874
01:51:24,320 --> 01:51:25,080
PLANS.

2875
01:51:25,080 --> 01:51:27,600
NEXT SLIDE PLEASE.

2876
01:51:27,600 --> 01:51:31,120
SO AS JOHN MENTIONED, THE BRAIN

2877
01:51:31,120 --> 01:51:32,200
INITIATIVE WAS ESTABLISHED IN

2878
01:51:32,200 --> 01:51:34,600
2013 BY PRESIDENT BARACK OBAMA,

2879
01:51:34,600 --> 01:51:36,040
AND ESSENTIALLY GAVE NIH THIS

2880
01:51:36,040 --> 01:51:38,200
GRAND CHALLENGE TO FIGURE OUT IN

2881
01:51:38,200 --> 01:51:40,200
THE FUTURE AND IMPETUS FOR THE

2882
01:51:40,200 --> 01:51:42,640
BRAIN RESEARCH EFFORT WAS REALLY

2883
01:51:42,640 --> 01:51:43,920
A SIMPLE STAGGERING STATISTIC

2884
01:51:43,920 --> 01:51:46,440
THAT ONE IN FOUR FAMILIES

2885
01:51:46,440 --> 01:51:47,320
WORLDWIDE INCLUDE SOMEONE WHO

2886
01:51:47,320 --> 01:51:50,080
SUFFERS FROM A BRAIN INJURY,

2887
01:51:50,080 --> 01:51:51,960
BRAIN DISEASE, BRAIN DISORDER.

2888
01:51:51,960 --> 01:51:53,920
THIS INITIATIVE HONES TO

2889
01:51:53,920 --> 01:51:54,680
ACCELERATE DEVELOPMENT OF

2890
01:51:54,680 --> 01:51:56,880
INNOVATIVE TECHNOLOGY TO

2891
01:51:56,880 --> 01:52:01,240
DISCOVER NEW THINGS, AND UTILIZE

2892
01:52:01,240 --> 01:52:02,560
INTERDISCIPLINARY RESEARCH.

2893
01:52:02,560 --> 01:52:09,040
THE PLAYBOOK ON HOW RESEARCH IS

2894
01:52:09,040 --> 01:52:10,120
DONE HAS BEEN DE-EMPHASIZED,

2895
01:52:10,120 --> 01:52:12,400
HIGH RISK, HIGH REWARD RESEARCH

2896
01:52:12,400 --> 01:52:14,000
PROJECTS HAVE BEEN EMBRACED FOR

2897
01:52:14,000 --> 01:52:14,640
THIS INITIATIVE.

2898
01:52:14,640 --> 01:52:17,040
IN ORDER TO DO THAT REALLY IT

2899
01:52:17,040 --> 01:52:19,240
TAKES SPECIAL ATTENTION BY

2900
01:52:19,240 --> 01:52:22,960
PROGRAM OFFICERS, SCIENTIFIC

2901
01:52:22,960 --> 01:52:25,040
REVIEW OFFICERS, REVIEWERS FROM

2902
01:52:25,040 --> 01:52:25,880
EXTRAMURAL COMMUNITY, AND

2903
01:52:25,880 --> 01:52:28,120
COUNCILS IN ORDER TO MAINTAIN

2904
01:52:28,120 --> 01:52:30,400
THIS MAVERICK APPROACH AND WE

2905
01:52:30,400 --> 01:52:32,360
KEEP THOSE IDEALS IN MIND.

2906
01:52:32,360 --> 01:52:34,240
ON THE SLIGHT THERE'S SEVEN HIGH

2907
01:52:34,240 --> 01:52:36,000
PRIORITY RESEARCH AREAS, AS JOHN

2908
01:52:36,000 --> 01:52:37,760
MENTIONED TWO WORKING GROUPS OF

2909
01:52:37,760 --> 01:52:39,280
EXPERTS HAVE HELPED CONTINUE TO

2910
01:52:39,280 --> 01:52:41,240
DEFINE DIRECTIONS AS WE MOVE

2911
01:52:41,240 --> 01:52:41,760
FORWARD.

2912
01:52:41,760 --> 01:52:43,920
I'M GOING TO UPDATE YOU BRIEFLY

2913
01:52:43,920 --> 01:52:47,080
ON HOW THE BRAIN INITIATIVE

2914
01:52:47,080 --> 01:52:48,160
INTERACTS WITH OUR MISSION,

2915
01:52:48,160 --> 01:52:53,760
BUILDING ON  MY LAST

2916
01:52:53,760 --> 01:52:54,640
PRESENTATION IN 2021.

2917
01:52:54,640 --> 01:52:57,680
WHAT DO WE HOPE TO GAIN?

2918
01:52:57,680 --> 01:52:58,560
WELL, I PERSONALLY MIGHT WANT TO

2919
01:52:58,560 --> 01:53:00,760
MAP THE BRAIN TO FIND MY CAR

2920
01:53:00,760 --> 01:53:03,080
KEYS OR REMEMBER MY COMPUTER

2921
01:53:03,080 --> 01:53:05,320
PASSWORDS THESE DAYS.

2922
01:53:05,320 --> 01:53:06,800
WHAT DOES NIDCD WANT?

2923
01:53:06,800 --> 01:53:08,000
ARE WE BENEFITING FROM MONEY

2924
01:53:08,000 --> 01:53:10,840
SPENT THROUGH THE BRAIN

2925
01:53:10,840 --> 01:53:11,280
INITIATIVE?

2926
01:53:11,280 --> 01:53:12,960
IT'S CLEAR AFTER SEVEN YEARS

2927
01:53:12,960 --> 01:53:14,720
THAT WE'RE GAINING SOME POWERFUL

2928
01:53:14,720 --> 01:53:19,200
GLOBAL TECHNIQUES AND TOOLS TO

2929
01:53:19,200 --> 01:53:21,160
ANSWER THESE QUESTIONS HELPING

2930
01:53:21,160 --> 01:53:22,040
ANSWER MISSION-RELATED

2931
01:53:22,040 --> 01:53:23,920
QUESTIONS, AND WE'RE DIRECTLY

2932
01:53:23,920 --> 01:53:24,240
BENEFITING.

2933
01:53:24,240 --> 01:53:26,000
I WANT TO TALK ABOUT HOW THE

2934
01:53:26,000 --> 01:53:27,400
MONEY IS BEING USED.

2935
01:53:27,400 --> 01:53:29,360
THE NEXT FEW SLIDES WILL

2936
01:53:29,360 --> 01:53:32,320
HIGHLIGHT THE PORTION OF GRANT

2937
01:53:32,320 --> 01:53:33,280
INITIATIVE FUNDED GRANTS.

2938
01:53:33,280 --> 01:53:36,040
GO BACK ONE.

2939
01:53:36,040 --> 01:53:36,240
SORRY.

2940
01:53:36,240 --> 01:53:38,320
THANKS, GINGER.

2941
01:53:38,320 --> 01:53:39,480
RELATED EITHER BY COUNTING

2942
01:53:39,480 --> 01:53:40,680
GRANTS DEVELOPING TOOLS RELATED

2943
01:53:40,680 --> 01:53:42,200
TO BE TESTED IN BRAIN AREAS

2944
01:53:42,200 --> 01:53:44,800
IMPORTANT TO OUR MISSION AREA,

2945
01:53:44,800 --> 01:53:47,000
SO TECHNOLOGY, OR THESE GRANTS

2946
01:53:47,000 --> 01:53:50,600
MIGHT BE USED IN A RELATED MODEL

2947
01:53:50,600 --> 01:53:52,240
SYSTEM SUCH AS OLFACTION WHICH

2948
01:53:52,240 --> 01:53:54,240
JOHN SHOWED IN HIS SLIDES OR

2949
01:53:54,240 --> 01:53:55,200
MIGHT BE STUDYING QUESTIONS THAT

2950
01:53:55,200 --> 01:53:59,360
ARE CRITICAL TO OUR MISSION

2951
01:53:59,360 --> 01:54:01,680
AREA. 

2952
01:54:01,680 --> 01:54:03,800
WHILE ALSO BROADY STUDYING

2953
01:54:03,800 --> 01:54:05,920
NEURAL CIRCUMSTANCES AND

2954
01:54:05,920 --> 01:54:06,720
BEHAVIORS.

2955
01:54:06,720 --> 01:54:09,880
I WOULD SAY MERAV AND I CAN TALK

2956
01:54:09,880 --> 01:54:14,040
TO YOU IN PERSON OR OVER ZOOM

2957
01:54:14,040 --> 01:54:22,120
ABOUT NEURAL CIRCUIT  CIRCUITRY

2958
01:54:22,120 --> 01:54:23,000
ACTIVITIES.

2959
01:54:23,000 --> 01:54:25,400
THE MONEY PASSES FROM CONGRESS

2960
01:54:25,400 --> 01:54:28,160
TO OUR INSTITUTE, NOT CODED AT

2961
01:54:28,160 --> 01:54:29,800
NIDCD SO IT TAKES DETECTIVE WORK

2962
01:54:29,800 --> 01:54:31,080
TO DISCOVERY WHICH GRANTS ARE

2963
01:54:31,080 --> 01:54:34,160
RELATED TO OUR VERY BROAD NIDCD

2964
01:54:34,160 --> 01:54:36,840
MISSION AREAS OF TASTE AND

2965
01:54:36,840 --> 01:54:39,080
SMELL, VOICE SPEECH AND

2966
01:54:39,080 --> 01:54:42,720
LANGUAGE, AND HEAR AND BALANCE.

2967
01:54:42,720 --> 01:54:43,800
NEXT SLIDE.

2968
01:54:43,800 --> 01:54:46,880
SHOWN HERE ARE RAW NUMBER OF

2969
01:54:46,880 --> 01:54:48,160
NIDCD-RELATED BRAIN INITIATIVE

2970
01:54:48,160 --> 01:54:51,560
GRANTS AWARDED OVER SEVEN YEARS

2971
01:54:51,560 --> 01:54:52,240
THROUGH 2021.

2972
01:54:52,240 --> 01:54:55,200
IN THE FIRST YEAR OF THE BRAIN

2973
01:54:55,200 --> 01:54:56,920
INITIATIVE IN 201458 GRANTS WERE

2974
01:54:56,920 --> 01:54:58,160
GIVEN OUT OVERALL WITH FOUR

2975
01:54:58,160 --> 01:55:01,880
RELATED IN SOME WAY TO OUR

2976
01:55:01,880 --> 01:55:03,240
MISSION AREAS.

2977
01:55:03,240 --> 01:55:06,920
LAST YEAR IN 2021 THAT NUMBER

2978
01:55:06,920 --> 01:55:10,120
GREW TO 221 OVERALL AND 21

2979
01:55:10,120 --> 01:55:18,440
GRANTS RELATED TO NIDCD.

2980
01:55:18,440 --> 01:55:19,400
REPRESENTS ABOUT 10%,

2981
01:55:19,400 --> 01:55:20,840
APPROPRIATE GIVEN IT INCLUDES

2982
01:55:20,840 --> 01:55:24,480
TEN INSTITUTES AND FOUR NIH

2983
01:55:24,480 --> 01:55:29,280
OFFICES AND NIH-WIDE

2984
01:55:29,280 --> 01:55:29,880
RESPONSIBILITIES.

2985
01:55:29,880 --> 01:55:30,800
THIS GRAPH REPRESENTS MILLIONS

2986
01:55:30,800 --> 01:55:35,280
OF DOLLARS TOTAL FIRST YEAR

2987
01:55:35,280 --> 01:55:36,720
RELATED TO NIDCD MISSION AREAS,

2988
01:55:36,720 --> 01:55:40,280
THIS IS THE FIRST YEAR TOTAL

2989
01:55:40,280 --> 01:55:43,640
COST, 2021, $41 MILLION AWARDED

2990
01:55:43,640 --> 01:55:45,480
FOR NIDCD-RELATED MISSION AREAS,

2991
01:55:45,480 --> 01:55:49,320
UP FROM $36 MILLION IN 2020.

2992
01:55:49,320 --> 01:55:50,720
THERE ARE LOTS OF -- THE NUMBER

2993
01:55:50,720 --> 01:55:53,320
MUCH GRANTS MIGHT NOT HAVE BEEN

2994
01:55:53,320 --> 01:55:54,680
INCREASED OVERALL, THE BUDGETS

2995
01:55:54,680 --> 01:55:56,400
ARE GETTING LARGER AND THERE ARE

2996
01:55:56,400 --> 01:55:58,000
LARGE U MECHANISM GRANTS WHICH

2997
01:55:58,000 --> 01:56:00,160
INCLUDE A LOT OF TEAM MEMBERS,

2998
01:56:00,160 --> 01:56:01,800
SO THOSE GRANTS ARE QUITE LARGE

2999
01:56:01,800 --> 01:56:05,040
AS WELL.

3000
01:56:05,040 --> 01:56:06,480
NEXT SLIDE PLEASE.

3001
01:56:06,480 --> 01:56:09,640
OUR INSTITUTE COVERS A LOT OF

3002
01:56:09,640 --> 01:56:10,520
DIFFERENT MISSION AREAS.

3003
01:56:10,520 --> 01:56:12,720
I'D LIKE TO SHOW SOME NUMBERS BY

3004
01:56:12,720 --> 01:56:16,520
MISSION AREA, TO BE EXACT.

3005
01:56:16,520 --> 01:56:18,600
NEXT SLIDE.

3006
01:56:18,600 --> 01:56:19,400
OVER SEVEN YEARS BRAIN

3007
01:56:19,400 --> 01:56:20,520
INITIATIVE GRANTS HAVE COVERED

3008
01:56:20,520 --> 01:56:24,760
ALL OF OUR MISSION AREAS WITH

3009
01:56:24,760 --> 01:56:25,760
MOSTLY OLFACTION, PRIMARILY

3010
01:56:25,760 --> 01:56:27,840
HEARING AND SOME BALANCE IN THE

3011
01:56:27,840 --> 01:56:29,040
SECOND GROUP, AND SPEECH

3012
01:56:29,040 --> 01:56:30,840
FOLLOWED BY LANGUAGE AND VOICE

3013
01:56:30,840 --> 01:56:32,200
IN THE LAST CATEGORY.

3014
01:56:32,200 --> 01:56:34,520
THE NUMBERS ARE SLIGHTLY LARGER

3015
01:56:34,520 --> 01:56:36,400
FOR HEARING AND BALANCE, IN

3016
01:56:36,400 --> 01:56:38,480
TERMS OF DOLLARS, NEXT SLIDE

3017
01:56:38,480 --> 01:56:42,000
PLEASE, IT SHOWS THAT THE

3018
01:56:42,000 --> 01:56:43,560
CHEMICAL CENSUS ACTUALLY

3019
01:56:43,560 --> 01:56:46,800
RECEIVED MORE THAN $200 MILLION

3020
01:56:46,800 --> 01:56:48,200
IN TOTAL FUNDING, ACROSS SEVEN

3021
01:56:48,200 --> 01:56:50,160
YEARS.

3022
01:56:50,160 --> 01:56:51,160
HEARING AND BALANCE WITH $143

3023
01:56:51,160 --> 01:56:53,880
MILLION, VOICE SPEECH AND

3024
01:56:53,880 --> 01:56:54,520
LANGUAGE WITH $93 MILLION OVER

3025
01:56:54,520 --> 01:56:57,520
THE PAST SEVEN YEARS.

3026
01:56:57,520 --> 01:56:59,040
THAT EQUALS ABOUT $437 MILLION

3027
01:56:59,040 --> 01:57:03,440
TOTAL FOR THE YEARS 2014-2021.

3028
01:57:03,440 --> 01:57:05,760
FOR COMPARISON, EACH YEAR NIDCD

3029
01:57:05,760 --> 01:57:09,000
AWARDS $85 MILLION IN NEW

3030
01:57:09,000 --> 01:57:09,800
COMPETING GRANTS, PLUS $14

3031
01:57:09,800 --> 01:57:12,200
MILLION FOR SMALL BUSINESS

3032
01:57:12,200 --> 01:57:12,840
GRANTS, TOTAL OF ABOUT $100

3033
01:57:12,840 --> 01:57:15,360
MILLION PER YEAR OF OUR BUDGET

3034
01:57:15,360 --> 01:57:17,480
GOES TO NEWLY AWARDED GRANTS.

3035
01:57:17,480 --> 01:57:19,080
SO COMPETING GRANTS.

3036
01:57:19,080 --> 01:57:21,760
AND IN 2021 THE BRAIN INITIATIVE

3037
01:57:21,760 --> 01:57:23,480
AWARDED $41 MILLION IN COMPETING

3038
01:57:23,480 --> 01:57:25,520
GRANTS RELATED TO OUR MISSION

3039
01:57:25,520 --> 01:57:26,880
AREAS WHICH EQUALS ROUGHLY 41%

3040
01:57:26,880 --> 01:57:28,600
OF WHAT WE TYPICALLY SPEND IN

3041
01:57:28,600 --> 01:57:31,720
TOTAL FOR NEW AWARDS EACH YEAR

3042
01:57:31,720 --> 01:57:32,560
AT NIDCD.

3043
01:57:32,560 --> 01:57:34,640
THESE DOLLARS ARE ADDING TO OUR

3044
01:57:34,640 --> 01:57:37,360
MISSION AREAS WITH TECHNOLOGY TO

3045
01:57:37,360 --> 01:57:38,760
UTILIZE AND ANSWER QUESTIONS, TO

3046
01:57:38,760 --> 01:57:40,440
DIRECTLY ANSWER SOME OF THE

3047
01:57:40,440 --> 01:57:43,200
QUESTIONS THAT WE HAVE RELATED

3048
01:57:43,200 --> 01:57:46,600
TO OUR MISSION. 

3049
01:57:46,600 --> 01:57:49,640
NEXT SLIDE PLEASE.

3050
01:57:49,640 --> 01:57:50,080
NEXT.

3051
01:57:50,080 --> 01:57:52,280
IN SUMMARY, NIDCD BENEFITS IN A

3052
01:57:52,280 --> 01:57:54,280
NUMBER OF INDIRECT WAYS FROM

3053
01:57:54,280 --> 01:57:55,600
BRAIN INITIATIVE FUNDING.

3054
01:57:55,600 --> 01:57:57,880
SO FIRST IS EXPANSION OF CUTTING

3055
01:57:57,880 --> 01:57:59,760
EDGE TECHNIQUES APPLIED TO OUR

3056
01:57:59,760 --> 01:58:01,560
MISSION AREAS, AND THIS GOES TO

3057
01:58:01,560 --> 01:58:03,360
ONE OF THE QUESTIONS ASKED

3058
01:58:03,360 --> 01:58:04,520
EARLIER, ACTUALLY DOES INCREASE

3059
01:58:04,520 --> 01:58:05,560
NUMBER OF INVESTIGATORS DOING

3060
01:58:05,560 --> 01:58:08,520
WORK IN OUR MISSION AREAS, SOME

3061
01:58:08,520 --> 01:58:11,160
INVESTIGATORS HAVE CHOSEN OUR

3062
01:58:11,160 --> 01:58:12,760
MODEL SYSTEM IN ORDER TO LOOK AT

3063
01:58:12,760 --> 01:58:13,640
THEIR NEW TECHNOLOGIES BECAUSE

3064
01:58:13,640 --> 01:58:15,600
IT TURNS OUT TO BE QUITE

3065
01:58:15,600 --> 01:58:17,640
ADVANTAGEOUS TO USE OLFACTION OR

3066
01:58:17,640 --> 01:58:19,200
AUDITORY, FOR EXAMPLE, TO DO

3067
01:58:19,200 --> 01:58:19,440
THAT.

3068
01:58:19,440 --> 01:58:21,560
AND SOME OF THE THINGS THAT ARE

3069
01:58:21,560 --> 01:58:24,040
TRANSLATIONAL FOR HUMANS ARE

3070
01:58:24,040 --> 01:58:25,920
BEST DONE IN SPEECH.

3071
01:58:25,920 --> 01:58:28,000
SO, IT'S REALLY GREAT THAT THIS

3072
01:58:28,000 --> 01:58:29,720
IS HELPING INCREASE THE NUMBER

3073
01:58:29,720 --> 01:58:30,600
OF INVESTIGATORS THAT CONTRIBUTE

3074
01:58:30,600 --> 01:58:32,600
BACK TO OUR MISSION AREAS.

3075
01:58:32,600 --> 01:58:36,520
AND ALSO ALL THE WAY DOWN TO NEW

3076
01:58:36,520 --> 01:58:37,280
TRAINING OPPORTUNITIES.

3077
01:58:37,280 --> 01:58:41,280
AND TRAINING WILL BE TALKED

3078
01:58:41,280 --> 01:58:44,200
ABOUT BY DR. RIVERA RENTAS.

3079
01:58:44,200 --> 01:58:46,560
NEXT SLIDE.

3080
01:58:46,560 --> 01:58:48,760
ON THIS SLIDE, IF WE CAN HIT

3081
01:58:48,760 --> 01:58:50,680
ENTER AGAIN, THIS IS JUST A

3082
01:58:50,680 --> 01:58:52,800
QUICK SAMPLING OF SOME TITLES

3083
01:58:52,800 --> 01:58:54,000
AND INVESTIGATORS ASSOCIATED

3084
01:58:54,000 --> 01:58:56,560
WITH THE GRANTS WE CONSIDER

3085
01:58:56,560 --> 01:58:57,160
NIDCD RELATED.

3086
01:58:57,160 --> 01:58:58,800
EVERY ONE OF OUR MISSIONARIES IS

3087
01:58:58,800 --> 01:59:00,560
OR HAS BEEN SUPPORTED BY THE

3088
01:59:00,560 --> 01:59:03,720
BRAIN INITIATIVE IN SOME WAY.

3089
01:59:03,720 --> 01:59:07,680
AND AS WE SCROLL I'D LIKE TO 

3090
01:59:07,680 --> 01:59:09,320
THANK DR. LISA KENNEDY, AND

3091
01:59:09,320 --> 01:59:11,080
OTHERS, FOR SUPPORT GATHERING

3092
01:59:11,080 --> 01:59:13,360
INFORMATION AND ALSO TO BRAIN

3093
01:59:13,360 --> 01:59:15,360
INITIATIVE PROGRAM OFFICERS HERE

3094
01:59:15,360 --> 01:59:15,760
AT NIDCD.

3095
01:59:15,760 --> 01:59:19,280
SO IF YOU COULD GO TO THE NEXT

3096
01:59:19,280 --> 01:59:19,480
SLIDE.

3097
01:59:19,480 --> 01:59:20,680
IT LISTS MY THANK YOU SLIDE.

3098
01:59:20,680 --> 01:59:23,600
IF YOU COULD GO TO THE NEXT

3099
01:59:23,600 --> 01:59:25,040
SLIDE THEN, I'D LIKE TO ORIENT

3100
01:59:25,040 --> 01:59:27,360
YOU TO THE REST OF THE BRAIN

3101
01:59:27,360 --> 01:59:28,640
INITIATIVE AGENDA.

3102
01:59:28,640 --> 01:59:34,600
NEXT WE'LL HAVE DR. SABRI, NEW

3103
01:59:34,600 --> 01:59:37,520
PROGRAM OFFICER, TO TALK ABOUT

3104
01:59:37,520 --> 01:59:38,520
HER OUTREACH EFFORTS.

3105
01:59:38,520 --> 01:59:42,560
DR. ROGER MILLER WILL TALK ABOUT

3106
01:59:42,560 --> 01:59:45,320
NO PROJECTS NEW NEUROMODULATION

3107
01:59:45,320 --> 01:59:46,160
TEAM, DR. RIVERA-RENTAS WILL

3108
01:59:46,160 --> 01:59:49,760
UPDATE US WITH TRAINING EFFORTS,

3109
01:59:49,760 --> 01:59:51,120
AND DR. BECKEL-MITCHENER WILL

3110
01:59:51,120 --> 01:59:58,920
FILL US IN ON ONGOING DIVERSITY 

3111
01:59:58,920 --> 01:59:59,360
EFFORTS.

3112
01:59:59,360 --> 02:00:09,560
THANK YOU. 

3113
02:00:12,080 --> 02:00:14,320
WE'LL HAVE TIME AT THE END FOR

3114
02:00:14,320 --> 02:00:18,720
MORE QUESTIONS AS WELL.

3115
02:00:18,720 --> 02:00:21,520
TAKE IT AWAY, MERAV.

3116
02:00:21,520 --> 02:00:31,560
 

3117
02:00:31,880 --> 02:00:33,400
>> ONE SECOND.

3118
02:00:33,400 --> 02:00:36,040
WHERE IS THE CAMERA?

3119
02:00:36,040 --> 02:00:39,440
 

3120
02:00:39,440 --> 02:00:41,280
>> WE CAN HEAR YOU.

3121
02:00:41,280 --> 02:00:42,720
>> OKAY, GREAT.

3122
02:00:42,720 --> 02:00:44,680
ALL THE BUTTONS DISAPPEARED.

3123
02:00:44,680 --> 02:00:48,080
THAT NEVER HAPPENED BEFORE, BUT

3124
02:00:48,080 --> 02:00:51,640
HERE WE GO.

3125
02:00:51,640 --> 02:01:01,680
 

3126
02:01:14,280 --> 02:01:16,680
>> WE CAN SEE YOUR SLIDES.

3127
02:01:16,680 --> 02:01:17,120
>> FANTASTIC.

3128
02:01:17,120 --> 02:01:19,440
THANK YOU, AMY AND JOHN AND DAN.

3129
02:01:19,440 --> 02:01:21,960
MOST OF MY SLIDES ACTUALLY

3130
02:01:21,960 --> 02:01:23,520
REPEAT WHAT YOU WERE TELLING US

3131
02:01:23,520 --> 02:01:25,560
ALL ABOUT, BUT IT'S ALWAYS GOOD

3132
02:01:25,560 --> 02:01:28,200
TO HEAR THINGS TWICE, OR THREE

3133
02:01:28,200 --> 02:01:28,760
TIMES.

3134
02:01:28,760 --> 02:01:31,720
SO HERE WE GO.

3135
02:01:31,720 --> 02:01:34,680
MY NAME IS MERAV SABRI, IN THE

3136
02:01:34,680 --> 02:01:37,480
TASTE AND SMELL AREA.

3137
02:01:37,480 --> 02:01:39,080
I'M ALSO THE NIDCD LIAISON TO

3138
02:01:39,080 --> 02:01:40,360
THE NIH BRAIN INITIATIVE.

3139
02:01:40,360 --> 02:01:42,840
TODAY I'M EXCITED TO TELL YOU

3140
02:01:42,840 --> 02:01:44,480
ABOUT OUR RECENT OUTREACH

3141
02:01:44,480 --> 02:01:47,360
ACTIVITIES TO PROMOTE SYNERGY

3142
02:01:47,360 --> 02:01:51,480
BETWEEN THE BRAIN INITIATIVE AND

3143
02:01:51,480 --> 02:01:53,800
NIDCD. 

3144
02:01:53,800 --> 02:01:58,160
A VIRTUAL SEMINAR WITH DR. MARIA

3145
02:01:58,160 --> 02:02:02,880
GEFFIN OF U PENN AND DR. SANES

3146
02:02:02,880 --> 02:02:03,760
OF NYU, POTENTIAL APPLICANTS

3147
02:02:03,760 --> 02:02:05,720
THAT ARE INTERESTED IN LEARNING

3148
02:02:05,720 --> 02:02:09,800
ABOUT THE NIH BRAIN PROGRAM AND

3149
02:02:09,800 --> 02:02:11,200
FUNDING OPPORTUNITIES.

3150
02:02:11,200 --> 02:02:13,280
APRIL 19 IT AIRED, ARCHIVED FOR

3151
02:02:13,280 --> 02:02:16,040
LATER VIEWING IN CASE YOU DIDN'T

3152
02:02:16,040 --> 02:02:16,880
CATCH IT.

3153
02:02:16,880 --> 02:02:21,640
YOU HAVE THE LINK IN THE CHAT

3154
02:02:21,640 --> 02:02:24,120
THAT DAN KINDLY PUT THERE.

3155
02:02:24,120 --> 02:02:24,960
AGENDA INCLUDED PRESENTATIONS

3156
02:02:24,960 --> 02:02:26,880
ABOUT GOALS AND PRIORITIES OF

3157
02:02:26,880 --> 02:02:29,520
THE BRAIN PROGRAM.

3158
02:02:29,520 --> 02:02:30,720
VARIOUS FUNDING OPPORTUNITIES.

3159
02:02:30,720 --> 02:02:34,760
SYNERGIES BETWEEN THE BRAIN

3160
02:02:34,760 --> 02:02:38,080
PROGRAM AND NIDCD, AND TALKS IN

3161
02:02:38,080 --> 02:02:39,360
THE NIDCD SPACE AREA.

3162
02:02:39,360 --> 02:02:49,880
WE HAD THE PLEASURE OF HEARING 

3163
02:02:52,880 --> 02:02:54,480
FROM DOCTORS DAVID, GEFFEN ABOUT

3164
02:02:54,480 --> 02:02:58,080
LESSONS ALONG THE WAY.

3165
02:02:58,080 --> 02:03:00,280
SEMINAR HIGHLIGHTED FUNDING

3166
02:03:00,280 --> 02:03:02,760
OPPORTUNITIES UNDER THE CIRCUIT

3167
02:03:02,760 --> 02:03:05,120
PROGRAM CROSS-CUTTING ACROSS

3168
02:03:05,120 --> 02:03:07,080
SEVERAL NIDCD MISSION AREAS.

3169
02:03:07,080 --> 02:03:08,960
THESE ARE THE DIFFERENT

3170
02:03:08,960 --> 02:03:10,680
ANNOUNCEMENTS UNDER THE CIRCUITS

3171
02:03:10,680 --> 02:03:11,120
PROGRAM.

3172
02:03:11,120 --> 02:03:13,560
YOU MIGHT ASK, WHY SO MANY?

3173
02:03:13,560 --> 02:03:15,520
THIS IS BY DESIGN BECAUSE WE

3174
02:03:15,520 --> 02:03:19,360
WANT TO ALLOW FOR FACULTY

3175
02:03:19,360 --> 02:03:22,080
QUESTIONS ON DIFFERENT SCALES

3176
02:03:22,080 --> 02:03:23,040
AND COMPLEXITIES.

3177
02:03:23,040 --> 02:03:24,680
WHICH ANNOUNCEMENT BEST FITS

3178
02:03:24,680 --> 02:03:25,680
YOUR PROJECT?

3179
02:03:25,680 --> 02:03:27,080
IT DEPENDS WHETHER THE PROJECT

3180
02:03:27,080 --> 02:03:29,280
IS STILL AT THE EXPLORATORY

3181
02:03:29,280 --> 02:03:29,840
STAGE.

3182
02:03:29,840 --> 02:03:35,720
IF THAT'S THE CASE, WE WOULD

3183
02:03:35,720 --> 02:03:39,800
RECOMMEND THE LEFT, NOT

3184
02:03:39,800 --> 02:03:41,440
REQUIRING PRELIMINARY DATA FOR

3185
02:03:41,440 --> 02:03:42,400
EXPLORATORY APPROACHES.

3186
02:03:42,400 --> 02:03:45,160
IN COMPARISON THE OPPORTUNITIES

3187
02:03:45,160 --> 02:03:46,680
ON THE RIGHT ARE RESEARCH

3188
02:03:46,680 --> 02:03:50,200
PROJECTS BUT REQUIRE STRONG

3189
02:03:50,200 --> 02:03:51,040
FEASIBILITY EVIDENCE.

3190
02:03:51,040 --> 02:03:53,880
IT DEPENDS ON THE SCALE OF THE

3191
02:03:53,880 --> 02:03:54,120
DESIGN.

3192
02:03:54,120 --> 02:03:56,760
IF THE PROJECT IS BY AN

3193
02:03:56,760 --> 02:04:00,440
INDIVIDUAL LAB, WE RECOMMEND OUR

3194
02:04:00,440 --> 02:04:01,520
R34 AND R01, FROM THE LARGE

3195
02:04:01,520 --> 02:04:11,920
SCALE TEAM YOU HAVE THE  U01 AND

3196
02:04:11,920 --> 02:04:12,720
UO 19.

3197
02:04:12,720 --> 02:04:16,560
CAN YOU EXPLORE BY VISITING THE

3198
02:04:16,560 --> 02:04:19,520
NIDCD OR BRAIN INITIATIVE WEB

3199
02:04:19,520 --> 02:04:20,040
PAGES.

3200
02:04:20,040 --> 02:04:22,240
THE SEMINAR CONCLUDED WITH LIVE

3201
02:04:22,240 --> 02:04:25,400
Q&A SESSION, SOME QUESTIONS
THAT

3202
02:04:25,400 --> 02:04:27,200
WERE ADDRESSED INCLUDE IF THE

3203
02:04:27,200 --> 02:04:34,200
BRAIN  INITIATIVE IS DISEASE

3204
02:04:34,200 --> 02:04:36,880
AGNOSTIC, IS EARLY STAGE OR NEW

3205
02:04:36,880 --> 02:04:38,480
INVESTIGATOR STATUS TAKEN INTO

3206
02:04:38,480 --> 02:04:39,320
CONSIDERATION IN FUNDING

3207
02:04:39,320 --> 02:04:41,200
DECISIONS, WHAT ARE THE

3208
02:04:41,200 --> 02:04:42,840
GUIDELINES FOR INCLUSION OF

3209
02:04:42,840 --> 02:04:46,760
PRELIMINARY DATA, THE BRAIN

3210
02:04:46,760 --> 02:04:47,560
APPLICANTS REQUIRE PRELIMINARY

3211
02:04:47,560 --> 02:04:51,160
DATA TO A LESSER EXTENT COMPARED

3212
02:04:51,160 --> 02:04:54,320
TO A PARENT R01, TAKEHOME

3213
02:04:54,320 --> 02:04:55,480
MESSAGES ARE THAT FOCUS OF THE

3214
02:04:55,480 --> 02:05:01,120
BRAIN PROGRAM IS ON THE DISEASE

3215
02:05:01,120 --> 02:05:01,760
AGNOSTIC TRANSFORMATIVE SCIENCE

3216
02:05:01,760 --> 02:05:04,400
BUT THERE ARE OTHER OPTIONS HERE

3217
02:05:04,400 --> 02:05:08,560
AS JOHN MENTIONED.

3218
02:05:08,560 --> 02:05:10,720
FUNDING DECISIONS TAKE INTO

3219
02:05:10,720 --> 02:05:12,280
CONSIDERATION STATUS OF

3220
02:05:12,280 --> 02:05:13,200
APPLICANT, SOME FUNDING

3221
02:05:13,200 --> 02:05:13,960
OPPORTUNITIES REQUIRE

3222
02:05:13,960 --> 02:05:15,920
PRELIMINARY DATA AND SOME DO

3223
02:05:15,920 --> 02:05:16,120
NOT.

3224
02:05:16,120 --> 02:05:18,320
IT IS IMPORTANT TO KEEP IN MIND

3225
02:05:18,320 --> 02:05:21,360
EACH ANNOUNCEMENT IS UNIQUE AND

3226
02:05:21,360 --> 02:05:24,360
INCLUDES DESCRIPTION OF SPECIFIC

3227
02:05:24,360 --> 02:05:25,200
REQUIREMENTS AND REVIEW

3228
02:05:25,200 --> 02:05:25,640
CRITERIA.

3229
02:05:25,640 --> 02:05:29,280
WE RECOMMEND THAT YOU READ THE

3230
02:05:29,280 --> 02:05:30,800
FUNDING ANNOUNCEMENT AND PAY

3231
02:05:30,800 --> 02:05:33,880
ATTENTION TO DETAILS.

3232
02:05:33,880 --> 02:05:35,440
LASTLY, EACH ANNOUNCEMENT

3233
02:05:35,440 --> 02:05:36,160
INCLUDES CONTACT INFORMATION.

3234
02:05:36,160 --> 02:05:37,800
IF YOU HAVE AN IDEA FOR A GRANT

3235
02:05:37,800 --> 02:05:45,680
WE WOULD LOVE TO HEAR FROM YOU. 

3236
02:05:45,680 --> 02:05:47,800
HERE WE'D LIKE TO TAKE THE

3237
02:05:47,800 --> 02:05:52,360
OPPORTUNITY TO THANK THE SEMINAR

3238
02:05:52,360 --> 02:05:53,800
ORGANIZERS AND PRESENTERS,

3239
02:05:53,800 --> 02:05:57,640
RECORDING IS AVAILABLE VIA THE

3240
02:05:57,640 --> 02:06:00,680
LINK ON THE WEB PAGE THAT I'LL

3241
02:06:00,680 --> 02:06:02,120
INTRODUCE NEXT.

3242
02:06:02,120 --> 02:06:06,080
THE NEW WEB PAGE WAS DEVELOPED

3243
02:06:06,080 --> 02:06:08,120
IN CLOSE COLLABORATION WITH A

3244
02:06:08,120 --> 02:06:10,000
TEAM AT THE NIDCD OFFICE OF

3245
02:06:10,000 --> 02:06:12,840
HEALTH COMMUNICATION AND PUBLIC

3246
02:06:12,840 --> 02:06:13,880
LIAISON.

3247
02:06:13,880 --> 02:06:18,080
YOU CAN ACCESS FROM NIDCD HOME

3248
02:06:18,080 --> 02:06:23,880
PAGE, CLICK ON THE DROPDOWN MENU

3249
02:06:23,880 --> 02:06:26,000
AND SELECT OR TYPE THE ADDRESS

3250
02:06:26,000 --> 02:06:27,480
INTO THE BROWSER.

3251
02:06:27,480 --> 02:06:32,160
IT INCLUDES INFORMATION ABOUT 

3252
02:06:32,160 --> 02:06:32,960
FUNDED APPLICATIONS, SEVERAL

3253
02:06:32,960 --> 02:06:37,560
MISSION AREAS, ON THE RIGHT

3254
02:06:37,560 --> 02:06:38,880
EXAMPLE OF AWARDS IN THE HEARING

3255
02:06:38,880 --> 02:06:39,320
SPACE.

3256
02:06:39,320 --> 02:06:45,120
YOU CAN SEE THE INVESTIGATOR,

3257
02:06:45,120 --> 02:06:45,760
INSTITUTE, FUNDING ANNOUNCEMENT,

3258
02:06:45,760 --> 02:06:47,000
AND ALSO YOU CAN SEE PROJECT

3259
02:06:47,000 --> 02:06:47,240
NUMBER.

3260
02:06:47,240 --> 02:06:49,400
IF YOU CLICK IT WILL TAKE YOU TO

3261
02:06:49,400 --> 02:06:54,200
THE NIH RECORDER FOR DETAILS.

3262
02:06:54,200 --> 02:06:56,840
NEXT WE PROVIDE LINKS TO ACTIVE

3263
02:06:56,840 --> 02:06:58,720
FUNDING ANNOUNCEMENT.

3264
02:06:58,720 --> 02:07:01,640
THERE ARE CURRENTLY 28 ACTIVE

3265
02:07:01,640 --> 02:07:01,960
OPPORTUNITIES.

3266
02:07:01,960 --> 02:07:05,920
YOU CAN FIND A LINK TO OUR

3267
02:07:05,920 --> 02:07:06,680
INFORMATIONAL SEMINAR.

3268
02:07:06,680 --> 02:07:08,360
IN ADDITION THERE IS A

3269
02:07:08,360 --> 02:07:10,600
DESCRIPTION OF THE PLAN FOR

3270
02:07:10,600 --> 02:07:11,600
ENHANCING DIVERSE PERSPECTIVES,

3271
02:07:11,600 --> 02:07:17,640
A NEW REQUIREMENT IN MOST BRAIN

3272
02:07:17,640 --> 02:07:20,160
FUNDING ANNOUNCEMENTS.

3273
02:07:20,160 --> 02:07:21,840
DR. BECKER MITCHINER WILL

3274
02:07:21,840 --> 02:07:25,280
PRESENT ON THIS TOPIC.

3275
02:07:25,280 --> 02:07:27,720
WHO SHOULD YOU CONTACT?

3276
02:07:27,720 --> 02:07:30,720
THIS LISTS CONTACTS, YOU HEARD

3277
02:07:30,720 --> 02:07:34,200
FROM DR. POREMBA, YOU WILL HEAR

3278
02:07:34,200 --> 02:07:37,040
FROM DOCTORS MILLER AND

3279
02:07:37,040 --> 02:07:37,480
RIVERA-RENTAS.

3280
02:07:37,480 --> 02:07:40,680
THE PAGE INCLUDES LINKS TO BRAIN

3281
02:07:40,680 --> 02:07:42,800
INITIATIVE EVENTS AND RESOURCES.

3282
02:07:42,800 --> 02:07:47,760
FOR LATEST UPDATES FOLLOW US ON

3283
02:07:47,760 --> 02:07:48,200
TWITTER.

3284
02:07:48,200 --> 02:07:50,760
I'LL END BY HIGHLIGHTING A

3285
02:07:50,760 --> 02:07:54,480
COMING EVENT JOHN HAS MENTIONED,

3286
02:07:54,480 --> 02:07:56,880
8th ANNUAL MEETING JUNE 21-22,

3287
02:07:56,880 --> 02:08:02,760
WE WILL BE A HYBRID EVENT, JOIN

3288
02:08:02,760 --> 02:08:04,880
US VIRTUALLY OR IN PERSON.

3289
02:08:04,880 --> 02:08:11,360
NOW OPEN TO DR. ROGER MILLER TO

3290
02:08:11,360 --> 02:08:17,320
HIGHLIGHT BRAIN TEAM B. 

3291
02:08:17,320 --> 02:08:18,520
>> MY PROGRAM AREA, I'D
LIKE TO

3292
02:08:18,520 --> 02:08:21,040
SHOW SYNERGIES IN THE NEXT TWO

3293
02:08:21,040 --> 02:08:25,040
SLIDES, I'LL BE BRIEF, FIVE

3294
02:08:25,040 --> 02:08:25,440
MINUTES.

3295
02:08:25,440 --> 02:08:26,840
NEXT SIDE PLEASE.

3296
02:08:26,840 --> 02:08:28,840
THIS SLIDE SHOWS ENERGY BETWEEN

3297
02:08:28,840 --> 02:08:32,440
A U01 FROM BRAIN TO HENDERSON AT

3298
02:08:32,440 --> 02:08:35,400
THE UNIVERSITY OF STANFORD, AND

3299
02:08:35,400 --> 02:08:38,240
U01 TO THE SAME TEAM AT STANFORD

3300
02:08:38,240 --> 02:08:38,880
UNIVERSITY.

3301
02:08:38,880 --> 02:08:43,320
JOHN REFERRED TO SOME OF THE 

3302
02:08:43,320 --> 02:08:50,720
GOALS OF THIS BRAIN-COMPUTER 

3303
02:08:50,720 --> 02:08:52,880
INTERFACE IN EARLIER SLIDES.

3304
02:08:52,880 --> 02:08:59,440
THE DEVICE IS A SMALL IMPLANT, 4

3305
02:08:59,440 --> 02:09:01,720
MILLIMETERS SQUARE, SMALLER THAN

3306
02:09:01,720 --> 02:09:08,880
A BABY ASPIRIN, A BED OF NAILS,

3307
02:09:08,880 --> 02:09:12,480
EACH 1.5 MILLIMETERS LONG,

3308
02:09:12,480 --> 02:09:16,840
BARELY PENETRATES THE CORTICAL

3309
02:09:16,840 --> 02:09:18,360
SURFACE TO RECORD SPECIFIC

3310
02:09:18,360 --> 02:09:19,400
NEURAL ACTIVITY.

3311
02:09:19,400 --> 02:09:22,400
THE CABLE LEADS BACK TO A

3312
02:09:22,400 --> 02:09:25,160
CONNECTOR OUTSIDE THE SKULL,

3313
02:09:25,160 --> 02:09:26,000
PERCUTANEOUS, ELECTRONICS ARE

3314
02:09:26,000 --> 02:09:27,280
THERE, WORKS WELL FOR RESEARCH

3315
02:09:27,280 --> 02:09:31,400
STUDIES BECAUSE IT CAN BE

3316
02:09:31,400 --> 02:09:31,720
RECONFIGURED.

3317
02:09:31,720 --> 02:09:33,480
STUDIES ARE DONE UNDER EARLY

3318
02:09:33,480 --> 02:09:36,520
FEASIBILITY STUDY FROM FDA AND

3319
02:09:36,520 --> 02:09:38,960
THIS TYPE OF INVESTIGATIVE

3320
02:09:38,960 --> 02:09:40,360
DEVICE EXEMPTION ALLOWS LIMITED

3321
02:09:40,360 --> 02:09:42,720
CLINICAL USE OF A DEVICE IN

3322
02:09:42,720 --> 02:09:44,000
EARLIEST STAGES OF DEVELOPMENT.

3323
02:09:44,000 --> 02:09:46,040
IT'S LIMITED TO A SMALL NUMBER

3324
02:09:46,040 --> 02:09:48,680
OF SUBJECTS, IN THIS CASE 21

3325
02:09:48,680 --> 02:09:52,120
SUBJECTS ACROSS BRAIN GATE 2

3326
02:09:52,120 --> 02:09:56,240
STUDIES, THERE BE A NUMBER OF

3327
02:09:56,240 --> 02:09:56,440
THEM.

3328
02:09:56,440 --> 02:09:58,000
IT ALLOWS INVESTIGATORS TO

3329
02:09:58,000 --> 02:09:58,760
EVALUATE DIFFERENT DEVICE

3330
02:09:58,760 --> 02:10:01,840
DESIGNS FOR SAFETY AND

3331
02:10:01,840 --> 02:10:02,160
FUNCTIONALITY.

3332
02:10:02,160 --> 02:10:03,600
WE PLACED A DEVICE INTO A HUMAN

3333
02:10:03,600 --> 02:10:07,040
SUBJECT FOR A YEAR OR MORE WE

3334
02:10:07,040 --> 02:10:09,680
HAVE MANY YEARS OF SAFETY DATA

3335
02:10:09,680 --> 02:10:10,360
ACROSS SUBJECTS PENETRATING

3336
02:10:10,360 --> 02:10:14,880
DIFFERENT AREAS OF THE CORTEX.

3337
02:10:14,880 --> 02:10:18,920
QUESTIONS ARISE ABOUT SPIKE

3338
02:10:18,920 --> 02:10:19,800
AMPLITUDE CHANGES, PLACEMENT,

3339
02:10:19,800 --> 02:10:22,840
HOW THIS CAN BE USED FOR

3340
02:10:22,840 --> 02:10:24,280
BRAIN-COMPUTER INTERFACE, AND

3341
02:10:24,280 --> 02:10:26,800
WE'RE ADDRESSING THOSE

3342
02:10:26,800 --> 02:10:30,440
QUESTIONS, GOOD SYNERGY.

3343
02:10:30,440 --> 02:10:32,080
EARLY FEASIBILITY STUDY IDE

3344
02:10:32,080 --> 02:10:35,360
ALLOWS YOU TO GET DATA TO GUIDE

3345
02:10:35,360 --> 02:10:37,240
DEVICE MODIFICATION, DEVICE CAN

3346
02:10:37,240 --> 02:10:38,320
CHANGE WITH ELECTRONICS OUTSIDE

3347
02:10:38,320 --> 02:10:40,600
THE BODY THAT ALLOWS FOR CHANGE

3348
02:10:40,600 --> 02:10:42,360
AND IN THE CURRENT

3349
02:10:42,360 --> 02:10:44,080
IMPLEMENTATION THERE'S TWO

3350
02:10:44,080 --> 02:10:45,680
ELECTRODE ARRAYS, SMALLER STILL,

3351
02:10:45,680 --> 02:10:47,640
PLACED IN DIFFERENT REGIONS TO

3352
02:10:47,640 --> 02:10:50,360
COVER BROADER REGION.

3353
02:10:50,360 --> 02:10:54,200
TOP AWARD TO HENDERSON AND

3354
02:10:54,200 --> 02:10:57,040
SHENOY ELECTRODES IN THE HAND

3355
02:10:57,040 --> 02:11:00,880
REGION, AS JOHN ILLUSTRATED IN

3356
02:11:00,880 --> 02:11:02,760
HIS TALK, NIDCD U01 LOWER,

3357
02:11:02,760 --> 02:11:07,840
ARRAYS PLACED IN DIFFERENT

3358
02:11:07,840 --> 02:11:11,800
AREAS, AND GOAL WOULD BE THAT

3359
02:11:11,800 --> 02:11:22,280
YOU WOULD A DIRECT TO SPEECH

3360
02:11:24,560 --> 02:11:29,960
BRAIN-COMPUTER INTERFACE.

3361
02:11:29,960 --> 02:11:33,800
WE'VE COLLABORATED AND HAVE A

3362
02:11:33,800 --> 02:11:36,440
SHARED BOARD.

3363
02:11:36,440 --> 02:11:41,640
THIS SHOWS SYNERGY FOR DISEASE

3364
02:11:41,640 --> 02:11:44,960
AGNOSTIC APPROACHES, AT THE TOP

3365
02:11:44,960 --> 02:11:48,600
AND BOTTOM.

3366
02:11:48,600 --> 02:11:51,440
NEXT SLIDE PLEASE.

3367
02:11:51,440 --> 02:11:58,440
HERE'S A DIFFERENT BCI, PREVIOUS

3368
02:11:58,440 --> 02:12:00,640
BCI REQUIRED FENESTRATION,

3369
02:12:00,640 --> 02:12:02,280
PERCUTANEOUS CONNECTOR AND

3370
02:12:02,280 --> 02:12:06,080
ELECTRODES AT SURFACE, THIS USES

3371
02:12:06,080 --> 02:12:07,640
STENT APPROACH, IN THE DIAGRAM

3372
02:12:07,640 --> 02:12:11,000
ON THE RIGHT-HAND SIDE YOU SEE A

3373
02:12:11,000 --> 02:12:14,000
GRAY TUBE, THAT'S THE CATHETER

3374
02:12:14,000 --> 02:12:14,840
INTRODUCING LIGHTLY COLORED

3375
02:12:14,840 --> 02:12:17,160
MESH, THAT'S THE STENT

3376
02:12:17,160 --> 02:12:18,600
ELECTRODE, INTO A BLOOD VESSEL,

3377
02:12:18,600 --> 02:12:21,560
ON THE SURFACE OF THE CORTEX,

3378
02:12:21,560 --> 02:12:25,240
THAT CAN BE ANYWHERE.

3379
02:12:25,240 --> 02:12:27,080
THERE'S 16 ELECTRODES THAT CAN

3380
02:12:27,080 --> 02:12:29,320
PICK UP NOT ELECTRODE NEURAL

3381
02:12:29,320 --> 02:12:32,080
ACTIVITY FROM PENETRATING INTO

3382
02:12:32,080 --> 02:12:34,120
THE BRAIN BUT AT REGIONS, A

3383
02:12:34,120 --> 02:12:37,320
DIFFERENT APPROACH BUT TRYING TO

3384
02:12:37,320 --> 02:12:39,960
GET NEURAL ACTIVITY MODULATED BY

3385
02:12:39,960 --> 02:12:44,320
USER TO CREATE A BRAIN-COMPUTER

3386
02:12:44,320 --> 02:12:47,040
INTERFACE. 

3387
02:12:47,040 --> 02:12:50,480
THIS AWARD TO DOUG WEBER, TO

3388
02:12:50,480 --> 02:12:52,320
PICK UP INTERFACE RELATED TO

3389
02:12:52,320 --> 02:12:55,280
DISCRETE ACTIONS, SUCH AS MENU

3390
02:12:55,280 --> 02:12:56,600
SELECTION, CLICK, ZOOM.

3391
02:12:56,600 --> 02:13:00,840
THE GOAL IS THAT THIS DEVICE CAN

3392
02:13:00,840 --> 02:13:03,120
BE USED IN A EARLY FEASIBILITY

3393
02:13:03,120 --> 02:13:06,320
STUDY WHICH WOULD FOLLOW FROM

3394
02:13:06,320 --> 02:13:08,520
THE UG3 AWARD, THE POINT TO GET

3395
02:13:08,520 --> 02:13:11,160
ALL THE PRELIMINARY DATA IN

3396
02:13:11,160 --> 02:13:18,800
PLACE, SUBMIT IDE APPLICATION TO

3397
02:13:18,800 --> 02:13:21,240
FDA, ILLUSTRATING A PARADIGM OF

3398
02:13:21,240 --> 02:13:22,640
BRAIN AWARDS, DIFFERENT

3399
02:13:22,640 --> 02:13:23,520
MECHANISMS, UNIQUE, DIFFERENT IN

3400
02:13:23,520 --> 02:13:26,360
CHARACTER FROM WHAT YOU'RE USED

3401
02:13:26,360 --> 02:13:29,080
TO FROM INVESTIGATOR INITIATED

3402
02:13:29,080 --> 02:13:30,400
R01, UG3s ARE COOPERATIVE,

3403
02:13:30,400 --> 02:13:31,480
HELPS INVESTIGATOR GET TO THE

3404
02:13:31,480 --> 02:13:38,720
POINT WHERE THEY CAN SUBMIT THE

3405
02:13:38,720 --> 02:13:40,120
IDE, UG 2, UG3 WILL TAKE YOU TO

3406
02:13:40,120 --> 02:13:42,760
THE POINT THEY CAN DO THE

3407
02:13:42,760 --> 02:13:44,160
CLINICAL TRIAL STUDIES.

3408
02:13:44,160 --> 02:13:47,680
THESE ARE TWO APPROACHES BOTH

3409
02:13:47,680 --> 02:13:49,200
FOR BRAIN-COMPUTER INTERFACE TO

3410
02:13:49,200 --> 02:13:50,400
SUPPORT COMMUNICATION BUT SHOWS

3411
02:13:50,400 --> 02:13:53,000
GOOD SYNERGY BETWEEN THE BRAIN

3412
02:13:53,000 --> 02:13:54,880
AWARDS AND NIDCD'S MISSION

3413
02:13:54,880 --> 02:13:55,240
AREAS.

3414
02:13:55,240 --> 02:14:01,560
I'LL TURN IT BACK OVER TO

3415
02:14:01,560 --> 02:14:02,320
INTRODUCE ALBERTO.

3416
02:14:02,320 --> 02:14:06,920
OR I CAN DO THAT.

3417
02:14:06,920 --> 02:14:08,680
>> YES PLEASE DO.

3418
02:14:08,680 --> 02:14:12,280
>> NEXT PRESENTATION FROM
DR.

3419
02:14:12,280 --> 02:14:18,320
RIVERA-RENTAS, TEAM TIE. 

3420
02:14:18,320 --> 02:14:18,560
>> OKAY.

3421
02:14:18,560 --> 02:14:19,520
RESEARCH TRAINING OFFICER, ALSO

3422
02:14:19,520 --> 02:14:26,000
MEMBER OF THE BRAIN TEAM TIE,

3423
02:14:26,000 --> 02:14:28,600
TRAINING INCLUSION AND EQUITY.

3424
02:14:28,600 --> 02:14:30,120
NEXT SLIDE PLEASE.

3425
02:14:30,120 --> 02:14:32,960
SO THE NAME SAYS WE SUPPORT

3426
02:14:32,960 --> 02:14:34,640
EVERYTHING THAT IS ABOUT

3427
02:14:34,640 --> 02:14:36,600
TRAINING, IN ADDITION TO

3428
02:14:36,600 --> 02:14:38,280
PROGRAMS ALSO DO WORKSHOPS, ET

3429
02:14:38,280 --> 02:14:43,120
CETERA, TO PEOPLE TO BE AWARE

3430
02:14:43,120 --> 02:14:48,960
AND TO ENGAGE PEOPLE WE HAVE 

3431
02:14:48,960 --> 02:14:49,360
BEEN FUNDING.

3432
02:14:49,360 --> 02:14:50,280
PRE-DOCTORAL LEVEL THANKS TO

3433
02:14:50,280 --> 02:14:53,360
EFFORTS FROM JOHN AND AGREEMENTS

3434
02:14:53,360 --> 02:14:57,320
WITH NIH BLUEPRINT WE

3435
02:14:57,320 --> 02:14:59,600
PARTICIPATE THROUGH "BRAIN" IN

3436
02:14:59,600 --> 02:15:02,320
THE DIVERSITY INITIATIVE,

3437
02:15:02,320 --> 02:15:05,800
DIVERSITY SPECIALIZED TO

3438
02:15:05,800 --> 02:15:09,680
POSTDOCTORAL ADVANCING

3439
02:15:09,680 --> 02:15:12,800
NEUROSCIENCE PROGRAM, F 99 K00

3440
02:15:12,800 --> 02:15:14,680
AWARD, TWO STAGE AWARD WHERE

3441
02:15:14,680 --> 02:15:16,520
DOCTORAL FELLOW GETS ONE OR TWO

3442
02:15:16,520 --> 02:15:17,560
YEARS OF PRE-DOCTORAL TRAINING,

3443
02:15:17,560 --> 02:15:20,160
FINISH THE DEGREE, MOVE INTO A

3444
02:15:20,160 --> 02:15:21,360
POSTDOCAL LEVEL, GO WITH THEIR

3445
02:15:21,360 --> 02:15:23,240
OWN MONEY FOR UP TO FOUR YEARS

3446
02:15:23,240 --> 02:15:28,920
OF FUNDING, IT'S A GREAT

3447
02:15:28,920 --> 02:15:30,800
PROGRAM.

3448
02:15:30,800 --> 02:15:32,000
MIMICKED BY OTHER INSTITUTES

3449
02:15:32,000 --> 02:15:35,920
AFTER THIS HAS STARTED AT THE

3450
02:15:35,920 --> 02:15:39,160
POSTDOCTORAL LEVEL WE HAVE THE

3451
02:15:39,160 --> 02:15:46,760
BRAIN INITIATIVE FELLOWS, 32

3452
02:15:46,760 --> 02:15:50,920
CONVENTIONAL POSTDOCAL 

3453
02:15:50,920 --> 02:15:54,960
FELLOWSHIP, AND TRANSLATION

3454
02:15:54,960 --> 02:16:00,040
AWARDS, K 99 R00 TO PROMOTE

3455
02:16:00,040 --> 02:16:03,600
DIVERSITY, A TARGETED

3456
02:16:03,600 --> 02:16:03,920
INITIATIVE.

3457
02:16:03,920 --> 02:16:06,440
THESE ARE FOR BASED ON

3458
02:16:06,440 --> 02:16:09,640
DIVERSITY, SEVERAL CATEGORIES OF

3459
02:16:09,640 --> 02:16:12,240
RACE, ETHNICITY, DISABILITY,

3460
02:16:12,240 --> 02:16:15,080
DISADVANTAGED BACKGROUNDS, ALSO

3461
02:16:15,080 --> 02:16:16,480
WOMEN OF THE POSTDOCTORAL AND

3462
02:16:16,480 --> 02:16:20,560
FACULTY LEVELS.

3463
02:16:20,560 --> 02:16:27,800
WE HAVE BEEN FORTUNATE IN 2020

3464
02:16:27,800 --> 02:16:35,040
HAVE A K99, AND IN 2021 DR.

3465
02:16:35,040 --> 02:16:39,040
HANSON IN THE CENSUS PORTFOLIO,

3466
02:16:39,040 --> 02:16:41,040
THIS YEAR DR. WOOD IN THE

3467
02:16:41,040 --> 02:16:43,840
HEARING AND BALANCE CENTRAL

3468
02:16:43,840 --> 02:16:45,560
AUDITORY RESEARCH PORTFOLIO SO

3469
02:16:45,560 --> 02:16:47,520
WE HAVE BEEN BENEFITING FROM

3470
02:16:47,520 --> 02:16:49,280
THESE PROGRAMS SIGNIFICANTLY.

3471
02:16:49,280 --> 02:16:52,320
LASTLY WE HAVE THE DIVERSITY

3472
02:16:52,320 --> 02:16:53,960
SUPPLEMENTS, THESE ARE

3473
02:16:53,960 --> 02:16:54,480
CONVENTIONAL DIVERSITY

3474
02:16:54,480 --> 02:16:56,280
SUPPLEMENTS FOR P.I.s THAT

3475
02:16:56,280 --> 02:16:58,560
ALREADY HAVE A BRAIN AWARD.

3476
02:16:58,560 --> 02:17:02,800
AND THEY APPLY THROUGH THE

3477
02:17:02,800 --> 02:17:04,040
CONVENTIONAL ANNOUNCEMENT.

3478
02:17:04,040 --> 02:17:04,920
THEY GET PRESENTED BY THE

3479
02:17:04,920 --> 02:17:07,640
PROGRAM OFFICERS AND WE HAVE

3480
02:17:07,640 --> 02:17:14,840
BEEN VERY SUPPORTIVE OF MANY OF 

3481
02:17:14,840 --> 02:17:23,320
THEM SO WE MEET EVERY MONTH TO 

3482
02:17:23,320 --> 02:17:28,320
INCREASE DISSEMINATION.

3483
02:17:28,320 --> 02:17:29,320
THANK YOU.

3484
02:17:29,320 --> 02:17:31,600
>> THANK YOU.

3485
02:17:31,600 --> 02:17:34,440
BACK TO YOU, AMY.

3486
02:17:34,440 --> 02:17:39,720
>> NOW DR. ANDREA

3487
02:17:39,720 --> 02:17:40,120
BECKEL-MITCHENER.

3488
02:17:40,120 --> 02:17:40,360
>> HI.

3489
02:17:40,360 --> 02:17:42,800
YES, CAN YOU HEAR ME?

3490
02:17:42,800 --> 02:17:44,280
>> YES.

3491
02:17:44,280 --> 02:17:45,200
>> GREAT.

3492
02:17:45,200 --> 02:17:48,240
WELL, I KNOW WE'RE RUNNING SHORT

3493
02:17:48,240 --> 02:17:49,840
ON TIME BUT LUCKILY MY

3494
02:17:49,840 --> 02:17:51,760
COLLEAGUES AND JOHN HAVE GIVEN

3495
02:17:51,760 --> 02:17:53,720
SUCH GREAT OVERVIEW I DON'T HAVE

3496
02:17:53,720 --> 02:17:55,880
TO SPENT A LOT OF TIME.

3497
02:17:55,880 --> 02:17:57,240
I JUST WANTED TO -- WE'RE HAPPY

3498
02:17:57,240 --> 02:18:01,160
TO BE HERE TO PRESENT A LITTLE

3499
02:18:01,160 --> 02:18:03,240
BIT MORE ON ONE OF THE NEW

3500
02:18:03,240 --> 02:18:04,480
THINGS, PLAN FOR ENHANCING

3501
02:18:04,480 --> 02:18:05,320
DIVERSE PERSPECTIVES.

3502
02:18:05,320 --> 02:18:07,160
I'M GOING TO SPEND THE MAJORITY

3503
02:18:07,160 --> 02:18:08,720
OF MY FEW MINUTES ON THAT.

3504
02:18:08,720 --> 02:18:11,800
I ALSO WANT TO MAKE THE POINT

3505
02:18:11,800 --> 02:18:15,520
BEFORE I START THAT BRAIN IS

3506
02:18:15,520 --> 02:18:21,760
REALLY ON THE FOREFRONT OF

3507
02:18:21,760 --> 02:18:23,400
INNOVATION, JOHN GAVE GREAT

3508
02:18:23,400 --> 02:18:24,040
EXAMPLES HOW INVESTIGATORS

3509
02:18:24,040 --> 02:18:25,360
FUNDED THROUGH THE BRAIN

3510
02:18:25,360 --> 02:18:27,040
INITIATIVE TACKLE THE MOST

3511
02:18:27,040 --> 02:18:28,240
CHALLENGING QUESTIONS IN

3512
02:18:28,240 --> 02:18:28,480
RESEARCH.

3513
02:18:28,480 --> 02:18:30,520
WE ALSO GOT A NICE OVERVIEW FROM

3514
02:18:30,520 --> 02:18:32,480
AMY ABOUT HOW WE'RE DOING THIS

3515
02:18:32,480 --> 02:18:33,920
DIFFERENTLY IN TERMS OF MANAGING

3516
02:18:33,920 --> 02:18:38,720
THE SCIENCE AND MANAGING THE 

3517
02:18:38,720 --> 02:18:43,560
INITIATIVE WITH 120 OR 130 STAFF

3518
02:18:43,560 --> 02:18:44,760
 ACROSS ALL TEN INSTITUTES THAT

3519
02:18:44,760 --> 02:18:47,040
SERVE AS MEMBERS OF THE PROJECT

3520
02:18:47,040 --> 02:18:50,640
TEAM IN SCIENCE, YOUR OWN GROUP

3521
02:18:50,640 --> 02:18:52,200
HERE, AMY, ROGER, ALBERTO, ARE

3522
02:18:52,200 --> 02:18:53,160
TERRIFIC PARTNERS IN THAT.

3523
02:18:53,160 --> 02:18:55,680
ONE OF THE OTHER MAJOR

3524
02:18:55,680 --> 02:18:56,560
CHALLENGES THAT WE'RE INTERESTED

3525
02:18:56,560 --> 02:18:58,000
IN ADDRESSING IS HOW DO WE

3526
02:18:58,000 --> 02:19:00,920
CHANGE THE CULTURE OF SCIENCE

3527
02:19:00,920 --> 02:19:02,280
AND CULTURE THAT NEUROSCIENCE IS

3528
02:19:02,280 --> 02:19:05,080
DONE, SO THAT'S WHERE MY TALK

3529
02:19:05,080 --> 02:19:06,720
REALLY IS SETTING THE STAGE FOR

3530
02:19:06,720 --> 02:19:07,080
THAT.

3531
02:19:07,080 --> 02:19:08,360
IT GOES BACK TO WHAT BRUCE

3532
02:19:08,360 --> 02:19:10,360
TALKED ABOUT EARLIER IN THE OPEN

3533
02:19:10,360 --> 02:19:11,760
SESSION THIS MORNING, SO WE'LL

3534
02:19:11,760 --> 02:19:16,280
BE TOUCHING ON SOME OF THOSE

3535
02:19:16,280 --> 02:19:16,600
THEMES.

3536
02:19:16,600 --> 02:19:20,440
SO, HAPPY TO BE HERE.

3537
02:19:20,440 --> 02:19:26,440
I THINK YOU CAN SEE MY SLIDES.

3538
02:19:26,440 --> 02:19:27,880
I WILL -- YEAH, THANK YOU.

3539
02:19:27,880 --> 02:19:32,600
I USED TO HAVE A QUOTE FROM A 

3540
02:19:32,600 --> 02:19:33,200
SCIENTIST BUT THIS CAPTURES A

3541
02:19:33,200 --> 02:19:35,000
LOT OF WHAT WE'RE TRYING TO DO

3542
02:19:35,000 --> 02:19:38,400
WITH PLAN FOR ENHANCING DIVERSE

3543
02:19:38,400 --> 02:19:38,720
PERSPECTIVES.

3544
02:19:38,720 --> 02:19:39,800
MICHELLE OBAMA IN HER BOOK SAID

3545
02:19:39,800 --> 02:19:42,520
WHAT I KNOW FROM WORKING IN

3546
02:19:42,520 --> 02:19:44,160
PROFESSIONAL ENVIRONMENTS IS

3547
02:19:44,160 --> 02:19:46,320
THAT SAMENESS BREEDS MORE

3548
02:19:46,320 --> 02:19:48,640
SAMENESS, UNTIL YOU MAKE A

3549
02:19:48,640 --> 02:19:50,280
THOUGHTFUL EFFORT TO COUNTERACT

3550
02:19:50,280 --> 02:19:51,560
IT, OUR STARTING POINT FOR WHAT

3551
02:19:51,560 --> 02:19:53,360
WE'RE TALKING ABOUT NOW.

3552
02:19:53,360 --> 02:19:55,200
WE KNOW THAT SUPPORTING THE BEST

3553
02:19:55,200 --> 02:19:56,560
SCIENCE AND THROUGH THE BRAIN

3554
02:19:56,560 --> 02:19:57,920
INITIATIVE IS THAT WE WANT TO

3555
02:19:57,920 --> 02:20:00,800
SUPPORT AND PROMOTE THE BROADEST

3556
02:20:00,800 --> 02:20:01,920
PERSPECTIVES IN RESEARCH.

3557
02:20:01,920 --> 02:20:06,840
AND WE DO THAT ACROSS A VARIETY

3558
02:20:06,840 --> 02:20:09,800
OF PARAMETERS. 

3559
02:20:09,800 --> 02:20:12,080
WE BELIEVE IN TRANSDISCIPLINARY

3560
02:20:12,080 --> 02:20:13,520
RESEARCH, MULTI-DISCIPLINARY

3561
02:20:13,520 --> 02:20:15,040
RESEARCH OF AWARDS,

3562
02:20:15,040 --> 02:20:15,520
COLLABORATIONS AMONG

3563
02:20:15,520 --> 02:20:16,360
NEUROSCIENTISTS AS WELL AS

3564
02:20:16,360 --> 02:20:18,880
INVESTIGATORS FROM A NUMBER OF

3565
02:20:18,880 --> 02:20:19,640
DIFFERENT FIELDS.

3566
02:20:19,640 --> 02:20:22,720
CAREER STAGE IS AN IMPORTANT

3567
02:20:22,720 --> 02:20:26,640
PART OF BRINGING IN DIVERSE

3568
02:20:26,640 --> 02:20:28,040
PERSPECTIVES, SENIOR SCIENTISTS,

3569
02:20:28,040 --> 02:20:29,800
LOTS OF TRAINEES, MORE JUNIOR

3570
02:20:29,800 --> 02:20:30,600
SCIENTISTS.

3571
02:20:30,600 --> 02:20:33,400
WE THINK THAT'S IMPORTANT.

3572
02:20:33,400 --> 02:20:34,760
OBVIOUSLY RECRUITING AND

3573
02:20:34,760 --> 02:20:35,720
SUPPORTING FUNDING INDIVIDUALS

3574
02:20:35,720 --> 02:20:37,840
FROM DIVERSE BACKGROUNDS SUCH AS

3575
02:20:37,840 --> 02:20:39,880
THOSE TRADITIONALLY

3576
02:20:39,880 --> 02:20:41,440
UNDERREPRESENTED IN SCIENCE

3577
02:20:41,440 --> 02:20:42,880
INCLUDING THOSE FROM

3578
02:20:42,880 --> 02:20:45,680
DISADVANTAGED BACKGROUNDS AND

3579
02:20:45,680 --> 02:20:46,000
WOMEN.

3580
02:20:46,000 --> 02:20:48,080
THE INSTITUTION TYPE, A QUESTION

3581
02:20:48,080 --> 02:20:49,520
RAISED EARLIER, WE THINK IS VERY

3582
02:20:49,520 --> 02:20:50,160
IMPORTANT.

3583
02:20:50,160 --> 02:20:52,040
WE'RE LOOKING TO ENGAGE

3584
02:20:52,040 --> 02:20:52,720
DIFFERENT INSTITUTIONS AND

3585
02:20:52,720 --> 02:20:54,120
ORGANIZATIONS IN THE RESEARCH

3586
02:20:54,120 --> 02:20:56,360
THAT WE FUND, EVERYTHING FROM

3587
02:20:56,360 --> 02:20:57,560
THE RESEARCH INTENSIVE

3588
02:20:57,560 --> 02:20:59,320
INSTITUTIONS THAT EVERYBODY IS

3589
02:20:59,320 --> 02:21:02,000
FAMILIAR WITH TO UNDERGRADUATE

3590
02:21:02,000 --> 02:21:12,440
FOCUSED INSTITUTIONS,  MINORITY

3591
02:21:12,440 --> 02:21:15,080
SERVING AND COMMUNITY BASED,

3592
02:21:15,080 --> 02:21:15,720
PROMOTING PARTNERSHIPS WITH

3593
02:21:15,720 --> 02:21:18,080
GEOGRAPHIC AND REGION NATURAL

3594
02:21:18,080 --> 02:21:18,680
HETEROGENEITY.

3595
02:21:18,680 --> 02:21:20,520
SO, AS JOHN MENTIONED WE'RE VERY

3596
02:21:20,520 --> 02:21:23,040
DATA DRIVEN AND ONE THING WE DO

3597
02:21:23,040 --> 02:21:25,320
EVERY YEAR IS COLLECT THE DATA

3598
02:21:25,320 --> 02:21:27,520
FROM THE PREVIOUS YEAR'S AWARDS.

3599
02:21:27,520 --> 02:21:29,520
AND REALLY LOOK AT ALL OF THOSE

3600
02:21:29,520 --> 02:21:31,240
AREAS THAT I JUST MENTIONED.

3601
02:21:31,240 --> 02:21:33,640
SO I'M GOING TO GIVE A FEW

3602
02:21:33,640 --> 02:21:35,280
EXAMPLES, I WON'T SPEND A LOT OF

3603
02:21:35,280 --> 02:21:37,680
TIME, BUT FOR EXAMPLE WE LOOK AT

3604
02:21:37,680 --> 02:21:40,320
HOW MANY WOMEN WE'RE FUNDING

3605
02:21:40,320 --> 02:21:41,840
ACROSS THE PORTFOLIO KNOWING

3606
02:21:41,840 --> 02:21:42,720
THAT THEY ARE UNDERREPRESENTED

3607
02:21:42,720 --> 02:21:44,840
IN SCIENCE AND IN NEUROSCIENCE.

3608
02:21:44,840 --> 02:21:47,560
AND YOU CAN SEE OUR NUMBERS ARE

3609
02:21:47,560 --> 02:21:48,400
QUITE LOW.

3610
02:21:48,400 --> 02:21:51,480
INTERESTINGLY THOUGH WE DO NOT

3611
02:21:51,480 --> 02:21:53,040
SEE APPARENTLY A DISPARITY IN

3612
02:21:53,040 --> 02:21:55,880
THE AWARDS THAT ARE MADE.

3613
02:21:55,880 --> 02:22:00,480
SO THE DARKER BARS THERE WE'VE

3614
02:22:00,480 --> 02:22:03,640
DONE THIS ACROSS WOMEN, CONTACT

3615
02:22:03,640 --> 02:22:05,160
P.I.s, MULTI-P.I. APPLICATION,

3616
02:22:05,160 --> 02:22:09,640
FUNDING RATES SHOWN IN THE FINAL

3617
02:22:09,640 --> 02:22:10,200
PANEL.

3618
02:22:10,200 --> 02:22:14,800
ONE THING YOU'LL NOTICE, THE

3619
02:22:14,800 --> 02:22:17,880
PURPLISH DIAMOND HERE IS THE NIH

3620
02:22:17,880 --> 02:22:21,680
2019 DATA AT THE TIME FOR WOMEN

3621
02:22:21,680 --> 02:22:23,320
CONTACT P.I.s, THE BRAIN

3622
02:22:23,320 --> 02:22:27,600
INITIATIVE NOT DOING AS WELL

3623
02:22:27,600 --> 02:22:28,560
COMPARED TO REFERENCE POPULATION

3624
02:22:28,560 --> 02:22:31,040
AT THE NIH IN GENERAL.

3625
02:22:31,040 --> 02:22:32,720
AGAIN, WE'RE NOT SEEING

3626
02:22:32,720 --> 02:22:33,760
DISPARITY ACROSS AWARD RATES SO

3627
02:22:33,760 --> 02:22:39,560
WE'RE A LITTLE BITTEN  -- A

3628
02:22:39,560 --> 02:22:40,440
LITTLE BIT ENCOURAGED BUT

3629
02:22:40,440 --> 02:22:42,640
NUMBERS ARE SMALL.

3630
02:22:42,640 --> 02:22:51,960
RACE AND ETHNICITY AWARD

3631
02:22:51,960 --> 02:22:52,920
AWARDEES, SLIGHTLY BETTER THAN

3632
02:22:52,920 --> 02:22:54,600
NIH AVERAGE BUT THESE DATA ARE

3633
02:22:54,600 --> 02:22:55,320
VERY NOISY.

3634
02:22:55,320 --> 02:22:57,240
WE HAVE A LOT OF UNKNOWNS IN

3635
02:22:57,240 --> 02:22:58,840
THIS CATEGORY SO WHILE WE CAN

3636
02:22:58,840 --> 02:23:00,800
MEASURE IT WE'RE NOT AT ALL

3637
02:23:00,800 --> 02:23:01,080
CONFIDENT.

3638
02:23:01,080 --> 02:23:04,440
WE KNOW OUR NUMBERS ARE VERY

3639
02:23:04,440 --> 02:23:13,160
LOW, THAT IS AN ISSUE.

3640
02:23:13,160 --> 02:23:13,960
MULTI-DISCIPLINARY, THERE'S TEAM

3641
02:23:13,960 --> 02:23:14,960
SCIENCE, WE LOOKED AT

3642
02:23:14,960 --> 02:23:17,440
COMPOSITION OF TEAMS.

3643
02:23:17,440 --> 02:23:20,840
MOST MULTI-P.I. TEAMS ARE MALE

3644
02:23:20,840 --> 02:23:22,040
AND NON-URM.

3645
02:23:22,040 --> 02:23:22,640
NOT SURPRISINGLY.

3646
02:23:22,640 --> 02:23:27,640
WE KNOW WE HAVE WORK TO DO.

3647
02:23:27,640 --> 02:23:29,960
A QUICK SUMMARY, WE DO

3648
02:23:29,960 --> 02:23:32,800
REASONABLY WELL WHEN LOOKING AT

3649
02:23:32,800 --> 02:23:34,320
DISCIPLINE OF THIS RESEARCHERS

3650
02:23:34,320 --> 02:23:38,960
THAT WE FUND, WE HAVE VERY LOW

3651
02:23:38,960 --> 02:23:40,000
NUMBERS OF UNDERREPRESENTED

3652
02:23:40,000 --> 02:23:41,280
GROUPS AND WOMEN RELATIVE TO NIH

3653
02:23:41,280 --> 02:23:45,320
AS A WHOLE, DATA ARE NOISY BUT

3654
02:23:45,320 --> 02:23:47,320
WE DON'T SEE ANY APPARENT

3655
02:23:47,320 --> 02:23:53,320
DISPARITY IN FUNDING RATE.

3656
02:23:53,320 --> 02:23:54,520
INSTITUTIONS, TAKE MY WORD FOR

3657
02:23:54,520 --> 02:23:57,440
IT, THE LINK WILL SHOW YOU ALL

3658
02:23:57,440 --> 02:23:59,320
THE DATA, MOST APPLICATIONS ARE

3659
02:23:59,320 --> 02:24:03,040
FROM AND MOST AWARDS GO TO

3660
02:24:03,040 --> 02:24:04,880
INSTITUTIONS THAT ARE LOCATED ON

3661
02:24:04,880 --> 02:24:05,680
THE COAST.

3662
02:24:05,680 --> 02:24:09,400
AND MOST OF OUR AWARDS GO TO

3663
02:24:09,400 --> 02:24:11,360
HIGHLY RESOURCED RESEARCH

3664
02:24:11,360 --> 02:24:12,040
INTENSIVE INSTITUTIONS,

3665
02:24:12,040 --> 02:24:14,040
PRIMARILY IN THREE STATES.

3666
02:24:14,040 --> 02:24:15,520
CALIFORNIA, NEW YORK,

3667
02:24:15,520 --> 02:24:15,960
MASSACHUSETTS.

3668
02:24:15,960 --> 02:24:17,560
AGAIN, NOT SURPRISING BUT ALSO

3669
02:24:17,560 --> 02:24:19,840
TOLD US WE HAD WORK TO DO.

3670
02:24:19,840 --> 02:24:21,200
I WON'T SPEND A LOT OF TIME ON

3671
02:24:21,200 --> 02:24:23,360
THIS BECAUSE I THINK EVERYBODY

3672
02:24:23,360 --> 02:24:26,360
UNDERSTANDS THE BENEFITS OF A

3673
02:24:26,360 --> 02:24:27,880
DIVERSE SCIENTIFIC WORKFORCE.

3674
02:24:27,880 --> 02:24:30,440
ALBERTO DID A WONDERFUL JOB ON

3675
02:24:30,440 --> 02:24:31,960
SOME DIVERSITY MECHANISMS SO I

3676
02:24:31,960 --> 02:24:34,880
WON'T GO INTO ANY DETAIL ON

3677
02:24:34,880 --> 02:24:36,680
THAT.

3678
02:24:36,680 --> 02:24:39,720
WE HAVE HAD SOME TARGETED

3679
02:24:39,720 --> 02:24:40,600
FUNDING OPPORTUNITIES THAT WE

3680
02:24:40,600 --> 02:24:43,240
HOPE WILL HELP US IN SOME OF THE

3681
02:24:43,240 --> 02:24:44,920
AREAS THAT WE NEED ASSISTANCE

3682
02:24:44,920 --> 02:24:49,400
WITH AND EXAMPLE OF THAT IS THIS

3683
02:24:49,400 --> 02:24:51,920
RESOURCE GRANT, U24 FUNDING

3684
02:24:51,920 --> 02:24:55,200
OPPORTUNITY, WHERE WE TARGETED

3685
02:24:55,200 --> 02:24:56,520
FUNDING FACILITIES AT

3686
02:24:56,520 --> 02:24:58,480
MINORITY-SERVING INSTITUTIONS

3687
02:24:58,480 --> 02:25:00,120
AND IDeA STATE ELIGIBLE

3688
02:25:00,120 --> 02:25:10,280
INSTITUTIONS TRYING TO BE

3689
02:25:10,280 --> 02:25:11,480
INTENTIONAL AND THOUGHTFUL.

3690
02:25:11,480 --> 02:25:13,720
AND A NEW PROGRAM PROMOTING

3691
02:25:13,720 --> 02:25:14,480
INCLUSIVE RESEARCH ENVIRONMENTS

3692
02:25:14,480 --> 02:25:17,400
BY REQUIRING A PLAN FOR

3693
02:25:17,400 --> 02:25:19,120
ENHANCING DIVERSE PERSPECTIVES

3694
02:25:19,120 --> 02:25:21,480
IN FUNDING ANNOUNCEMENT.

3695
02:25:21,480 --> 02:25:24,880
SO, AGAIN, NOVEL APPROACH,

3696
02:25:24,880 --> 02:25:26,440
INNOVATIVE ACROSS NIH IN

3697
02:25:26,440 --> 02:25:27,280
GENERAL.

3698
02:25:27,280 --> 02:25:28,920
WHAT IS THIS?

3699
02:25:28,920 --> 02:25:32,520
WE'RE REQUIRING THAT ALL

3700
02:25:32,520 --> 02:25:34,920
APPLICATIONS FOR BRAIN

3701
02:25:34,920 --> 02:25:36,880
INITIATIVE FOAs INCLUDE PLAN

3702
02:25:36,880 --> 02:25:38,440
FOR ENHANCING DIVERSE

3703
02:25:38,440 --> 02:25:41,040
PERSPECTIVES, SHORT HAND IS PEDP

3704
02:25:41,040 --> 02:25:43,600
WHICH I WILL SAY FROM HERE ON

3705
02:25:43,600 --> 02:25:45,000
OUT INCLUDING STRATEGIES

3706
02:25:45,000 --> 02:25:45,880
INCLUDED IN RESEARCH STRATEGY,

3707
02:25:45,880 --> 02:25:49,360
MAIN BODY OF THE GRANT, AND ALSO

3708
02:25:49,360 --> 02:25:50,920
REQUIRES A ONE-PAGE SUMMARY TO

3709
02:25:50,920 --> 02:25:56,360
BE INCLUDED IN THOSE

3710
02:25:56,360 --> 02:25:56,720
APPLICATIONS.

3711
02:25:56,720 --> 02:25:58,760
IMPORTANTLY AND NEW TO THE

3712
02:25:58,760 --> 02:26:00,160
PROCESS IS THIS PLAN WILL BE

3713
02:26:00,160 --> 02:26:05,080
PART OF THE SCORED APPLICATION,

3714
02:26:05,080 --> 02:26:07,200
HAS BEEN CONSIDERED WHEN FUNDING

3715
02:26:07,200 --> 02:26:08,360
DECISIONS ARE BEING MADE.

3716
02:26:08,360 --> 02:26:10,040
WHY IS IT BEING IMPLEMENTED?

3717
02:26:10,040 --> 02:26:14,200
I JUST MENTIONED ALL OF THIS.

3718
02:26:14,200 --> 02:26:18,280
WE THINK DIVERSE TEAMS

3719
02:26:18,280 --> 02:26:20,480
OUTPERFORM HOMOGENOUS TEAMS.

3720
02:26:20,480 --> 02:26:23,120
WE'RE COMMITTED TO FOSTERING

3721
02:26:23,120 --> 02:26:24,760
INCLUSIVE RESEARCH CULTURE.

3722
02:26:24,760 --> 02:26:27,400
AND IT REPRESENTS AN EXPLICIT

3723
02:26:27,400 --> 02:26:29,800
ALIGNMENT OF THOSE VALUES AS

3724
02:26:29,800 --> 02:26:34,720
WELL AS THE PROCESS WHERE WE CAN

3725
02:26:34,720 --> 02:26:37,400
FUND -- - PUT THIS IN FUNDING

3726
02:26:37,400 --> 02:26:38,600
ANNOUNCEMENT, HAVE PEER REVIEW

3727
02:26:38,600 --> 02:26:41,200
TAKE A LOOK, CONSIDERED WITH

3728
02:26:41,200 --> 02:26:42,640
FUNDING RECOMMENDATIONS AND

3729
02:26:42,640 --> 02:26:44,240
FUNDING DECISIONS, ALL OF WHICH

3730
02:26:44,240 --> 02:26:47,040
WE HOPE WILL EXPAND INCLUSIVITY

3731
02:26:47,040 --> 02:26:49,160
IN THE RESEARCH AREA.

3732
02:26:49,160 --> 02:26:55,960
WHAT DO WE MEAN BY DIVERSE PER 

3733
02:26:55,960 --> 02:26:57,840
PERSPECTIVES, PEOPLE WHO DO THE

3734
02:26:57,840 --> 02:26:58,760
RESEARCH, WHO PARTICIPATE IN

3735
02:26:58,760 --> 02:27:01,120
RESEARCH AS PART OF A STUDY

3736
02:27:01,120 --> 02:27:03,960
POPULATION, I.E. HUMAN SUBJECTS,

3737
02:27:03,960 --> 02:27:07,680
AND FINALLY THE PLACES WHERE THE

3738
02:27:07,680 --> 02:27:08,800
RESEARCH IS DONE.

3739
02:27:08,800 --> 02:27:10,080
POTENTIAL STRATEGIES THAT AN

3740
02:27:10,080 --> 02:27:11,520
INVESTIGATOR MIGHT INCLUDE IN

3741
02:27:11,520 --> 02:27:12,960
GRANT APPLICATION ARE LISTED IN

3742
02:27:12,960 --> 02:27:14,440
THESE BULLET POINTS BUT THESE

3743
02:27:14,440 --> 02:27:16,640
ARE NOT EXHAUSTIVE IN ANY WAY,

3744
02:27:16,640 --> 02:27:19,040
SHAPE OR FORM.

3745
02:27:19,040 --> 02:27:22,560
AGAIN, INCLUSION OF WOMEN,

3746
02:27:22,560 --> 02:27:24,200
INDIVIDUALS FROM

3747
02:27:24,200 --> 02:27:26,600
UNDERREPRESENTED GROUPS, KEY

3748
02:27:26,600 --> 02:27:30,920
PERSONNEL, PERHAPS TRAINING OR

3749
02:27:30,920 --> 02:27:31,880
MENTORING OPPORTUNITIES AN

3750
02:27:31,880 --> 02:27:32,680
INVESTIGATOR MIGHT PROMOTE,

3751
02:27:32,680 --> 02:27:34,160
DESCRIPTION OF PLANNED

3752
02:27:34,160 --> 02:27:37,120
PARTNERSHIPS THAT ENHANCE

3753
02:27:37,120 --> 02:27:39,840
GEOGRAPHIC HETEROGENEITY, ANY

3754
02:27:39,840 --> 02:27:40,960
CAREER ENHANCING OPPORTUNITIES

3755
02:27:40,960 --> 02:27:43,880
FOR EARLY OR MID-CAREER OR

3756
02:27:43,880 --> 02:27:46,520
TRAINEES THAT ARE INVOLVED IN

3757
02:27:46,520 --> 02:27:47,520
THE PROJECT.

3758
02:27:47,520 --> 02:27:50,360
ANY OPPORTUNITIES TO ADVANCE

3759
02:27:50,360 --> 02:27:52,760
TRANSDISCIPLINARY NATURE OF THE

3760
02:27:52,760 --> 02:27:53,040
RESEARCH.

3761
02:27:53,040 --> 02:27:54,920
ACTIVITIES THAT, AGAIN, HELP

3762
02:27:54,920 --> 02:27:56,920
WITH RECRUITMENT OF DIVERSE

3763
02:27:56,920 --> 02:27:58,880
RESEARCH PARTICIPANTS.

3764
02:27:58,880 --> 02:28:03,360
AND OUTREACH ACTIVITIES THAT MAY

3765
02:28:03,360 --> 02:28:04,360
ENGAGE SPECIFIC STAKEHOLDERS

3766
02:28:04,360 --> 02:28:07,520
THAT WOULDN'T OTHERWISE BE

3767
02:28:07,520 --> 02:28:09,840
INVOLVED, EDUCATORS, PATIENT

3768
02:28:09,840 --> 02:28:13,240
GROUPS, PATIENTS, POLICYMAKERS. 

3769
02:28:13,240 --> 02:28:15,640
WHAT ARE KEY ELEMENTS?

3770
02:28:15,640 --> 02:28:18,920
WRITE APPLICATION, THERE WILL BE

3771
02:28:18,920 --> 02:28:21,000
SUMMARIZED STRATEGIES TO ADVANCE

3772
02:28:21,000 --> 02:28:22,440
SCIENTIFIC MERIT THROUGH

3773
02:28:22,440 --> 02:28:23,920
EXPANDED INCLUSIVITY.

3774
02:28:23,920 --> 02:28:26,440
WE ASKED THAT INVESTIGATOR

3775
02:28:26,440 --> 02:28:28,080
INCLUDE TIMELINE, MILESTONES,

3776
02:28:28,080 --> 02:28:30,280
BENCHMARKS FOR THE PEDP AS WELL

3777
02:28:30,280 --> 02:28:34,880
AS APPROACHES TO DISCUSSING 

3778
02:28:34,880 --> 02:28:38,520
PROGRESS TOWARDS THOSE GOALS.

3779
02:28:38,520 --> 02:28:40,560
PEDP SHOULD REFLECT CAREFUL

3780
02:28:40,560 --> 02:28:41,680
CONSIDERATION HOW THESE

3781
02:28:41,680 --> 02:28:45,040
PERSPECTIVES WILL BENEFIT THE

3782
02:28:45,040 --> 02:28:45,520
PROJECT.

3783
02:28:45,520 --> 02:28:46,680
CONSIDERATIONS ARE INCLUDED IN

3784
02:28:46,680 --> 02:28:48,800
EACH OF THE SCORED REVIEW

3785
02:28:48,800 --> 02:28:52,000
CRITERIA, SO WE'RE ALL FAMILIAR,

3786
02:28:52,000 --> 02:28:52,840
SIG ADVANCE, INNOVATION,

3787
02:28:52,840 --> 02:28:54,800
INVESTIGATORS, APPROACH,

3788
02:28:54,800 --> 02:28:55,120
ENVIRONMENT.

3789
02:28:55,120 --> 02:28:56,880
THERE'S A PEDP-SPECIFIC QUESTION

3790
02:28:56,880 --> 02:29:02,040
UNDER EACH FOR ALL BRAIN FUNDING

3791
02:29:02,040 --> 02:29:02,400
ANNOUNCEMENTS.

3792
02:29:02,400 --> 02:29:04,040
AGAIN, MENTIONED WE'LL

3793
02:29:04,040 --> 02:29:05,480
CONTRIBUTE TO CRITERION SCORES

3794
02:29:05,480 --> 02:29:08,280
AS WELL AS OVERALL IMPACT SCORE

3795
02:29:08,280 --> 02:29:09,400
OF THE APPLICATION.

3796
02:29:09,400 --> 02:29:11,800
APPLICATIONS THAT DON'T HAVE A

3797
02:29:11,800 --> 02:29:12,520
PEDP ARE CONSIDERED INCOMPLETE

3798
02:29:12,520 --> 02:29:14,600
AND THEY HAVE BEEN WITHDRAWN.

3799
02:29:14,600 --> 02:29:17,160
WE'VE HAD ONE EXAMPLE.

3800
02:29:17,160 --> 02:29:19,560
THANKFULLY NOT MANY BUT THERE

3801
02:29:19,560 --> 02:29:20,440
WAS ONE.

3802
02:29:20,440 --> 02:29:25,600
PEDP, HOW  IT REVIEWED AS WELL

3803
02:29:25,600 --> 02:29:28,440
AS PART OF THE FUNDING

3804
02:29:28,440 --> 02:29:30,120
RECOMMENDATIONS AND DECISIONS

3805
02:29:30,120 --> 02:29:32,480
THAT GO TO LEADERSHIP.

3806
02:29:32,480 --> 02:29:34,800
WE UNDERSTAND THAT EACH PEDP

3807
02:29:34,800 --> 02:29:37,120
WILL VARY, DEPENDING ON THE

3808
02:29:37,120 --> 02:29:40,960
CONTENT AND STRUCTURE OF AIMS,

3809
02:29:40,960 --> 02:29:43,240
EXPERTISE REQUIRED, ENVIRONMENT,

3810
02:29:43,240 --> 02:29:44,320
PERFORMANCE, ET CETERA.

3811
02:29:44,320 --> 02:29:46,320
ALSO IT'S IMPORTANT TO NOTE WE

3812
02:29:46,320 --> 02:29:49,120
ARE THE FUNDING

3813
02:29:49,120 --> 02:29:51,400
ANNOUNCEMENT THAT INVESTIGATORS

3814
02:29:51,400 --> 02:29:54,600
CAN ASK FOR ALLOWABLE EXPENSES

3815
02:29:54,600 --> 02:29:59,640
ASSOCIATE  ASSOCIATED WITH THE

3816
02:29:59,640 --> 02:30:02,680
PEDP AND ITS IMPLEMENTATION.

3817
02:30:02,680 --> 02:30:06,520
I WON'T GO INTO DETAIL, AS WE'VE

3818
02:30:06,520 --> 02:30:08,200
IMPLEMENTED, WE HAVE TRIED TO

3819
02:30:08,200 --> 02:30:11,280
CLEARLY DEFINE THE SCOPE OF THE

3820
02:30:11,280 --> 02:30:15,080
PEDP AND DO OUTREACH AND EDUCATE

3821
02:30:15,080 --> 02:30:16,200
STAKEHOLDERS AGAIN BY

3822
02:30:16,200 --> 02:30:16,960
DISSEMINATING INFORMATION

3823
02:30:16,960 --> 02:30:18,520
BROADLY, WE WANT THIS CONSISTENT

3824
02:30:18,520 --> 02:30:24,680
MESSAGE SO EVERYBODY IS ON THE

3825
02:30:24,680 --> 02:30:25,200
SAME PAGE, FACILITATING

3826
02:30:25,200 --> 02:30:27,160
CONSIDERATION OF THE PEDP

3827
02:30:27,160 --> 02:30:29,000
ELEMENT THROUGH PRE-AWARD AND

3828
02:30:29,000 --> 02:30:30,480
POST AWARD PROCESSES FOR

3829
02:30:30,480 --> 02:30:31,560
INTERNAL PROCESSES.

3830
02:30:31,560 --> 02:30:34,280
AND SO WHAT HAVE WE DONE?

3831
02:30:34,280 --> 02:30:37,120
LOTS OF GUIDANCE MATERIALS

3832
02:30:37,120 --> 02:30:39,960
AVAILABLE, WE HAVE IN PLANS A

3833
02:30:39,960 --> 02:30:41,640
WEBINAR, INCLUDED IT IN OTHER

3834
02:30:41,640 --> 02:30:43,480
INFORMATION THAT HAS GONE TO

3835
02:30:43,480 --> 02:30:45,120
REVIEWERS, FOR EXAMPLE.

3836
02:30:45,120 --> 02:30:48,400
WE'VE PUT OUT SOME PUBLICATIONS,

3837
02:30:48,400 --> 02:30:49,840
HAVE THIS COMMUNICATIONS

3838
02:30:49,840 --> 02:30:51,160
FRAMEWORK OUR COMMUNICATIONS

3839
02:30:51,160 --> 02:30:53,680
GROUP HAS WORKED ON.

3840
02:30:53,680 --> 02:30:57,680
AND WE HAVE UPDATED INTERNALLY

3841
02:30:57,680 --> 02:31:00,760
SOPs FOR BRAIN STAFF SO

3842
02:31:00,760 --> 02:31:01,840
THERE'S CONSISTENCY, UNIFORMITY

3843
02:31:01,840 --> 02:31:03,800
AS THEY CONSIDER THIS AND THEY

3844
02:31:03,800 --> 02:31:08,400
HAVE JUST RESPONDED IN AMAZING

3845
02:31:08,400 --> 02:31:08,600
WAYS.

3846
02:31:08,600 --> 02:31:10,200
EXAMPLES OF OUTREACH MATERIAL

3847
02:31:10,200 --> 02:31:11,040
WE'VE DEVELOPED.

3848
02:31:11,040 --> 02:31:13,120
YOU'LL GET A COPY OF THE SLIDES,

3849
02:31:13,120 --> 02:31:16,080
YOU'LL SEE WE HAVE A NOTICE OUT

3850
02:31:16,080 --> 02:31:18,280
IN THE GUIDE, JOHN PUT IT IN A

3851
02:31:18,280 --> 02:31:18,920
DIRECTOR'S MESSAGE.

3852
02:31:18,920 --> 02:31:22,240
WE HAD A PAPER OUT IN NEURON

3853
02:31:22,240 --> 02:31:24,480
LAST YEAR WHERE THE PEDP WAS

3854
02:31:24,480 --> 02:31:26,200
INCLUDED IN MUCH OF THE

3855
02:31:26,200 --> 02:31:27,480
INFORMATION YOU'RE SEEING HERE

3856
02:31:27,480 --> 02:31:30,320
IN THAT PAPER, LOTS OF TALKING

3857
02:31:30,320 --> 02:31:31,880
POINTS AND AN E-MAIL ACCOUNT SET

3858
02:31:31,880 --> 02:31:35,240
UP WHERE WE ANSWER QUESTIONS

3859
02:31:35,240 --> 02:31:37,560
FROM ANY INTERESTED PARTIES OR

3860
02:31:37,560 --> 02:31:38,520
APPLICANTS.

3861
02:31:38,520 --> 02:31:41,200
HERE IS A LIST OF THE FUNDING

3862
02:31:41,200 --> 02:31:43,400
ANNOUNCEMENTS ACTIVE OR HAVE

3863
02:31:43,400 --> 02:31:47,240
CLOSED FOR THE BRAIN INITIATIVE.

3864
02:31:47,240 --> 02:31:49,000
YOU'LL SEE A NUMBER OF

3865
02:31:49,000 --> 02:31:50,720
ANNOUNCEMENTS NOW.

3866
02:31:50,720 --> 02:31:58,880
WHAT WE'RE PROUD OF, PICKED UP

3867
02:31:58,880 --> 02:32:00,360
ACROSS NIH IN NON-BRAIN.

3868
02:32:00,360 --> 02:32:02,680
ON THE RIGHT PROGRAMS AND

3869
02:32:02,680 --> 02:32:03,760
INDIVIDUAL INSTITUTES THAT FELT

3870
02:32:03,760 --> 02:32:05,560
THIS WAS AN IMPORTANT ADDITION

3871
02:32:05,560 --> 02:32:08,560
FOR THEIR FUNDING OPPORTUNITIES

3872
02:32:08,560 --> 02:32:09,200
AS WELL.

3873
02:32:09,200 --> 02:32:14,280
YOU'LL SEE THE DOTTED SQUARE,

3874
02:32:14,280 --> 02:32:15,840
MAY MULTI-COUNCIL WORK GROUP

3875
02:32:15,840 --> 02:32:19,440
MEETING, WE'RE IN THE MIDDLE OF

3876
02:32:19,440 --> 02:32:20,840
MAKING FUNDING DECISIONS, AND

3877
02:32:20,840 --> 02:32:24,800
IT'S BEEN GRATIFYING TO SEE

3878
02:32:24,800 --> 02:32:26,320
CONTENT IN PEDPs, HOW

3879
02:32:26,320 --> 02:32:29,400
APPLICANTS CONCEIVED OF IT AND

3880
02:32:29,400 --> 02:32:31,040
HOW STAFF HAVE HELPED US

3881
02:32:31,040 --> 02:32:35,400
EVALUATE THOSE AND MAKE FUNDING

3882
02:32:35,400 --> 02:32:36,320
RECOMMENDATIONS ACCORDINGLY.

3883
02:32:36,320 --> 02:32:37,920
EVERY TIME LINE, THESE WERE THE

3884
02:32:37,920 --> 02:32:40,120
FIRST ONES THAT CAME IN,

3885
02:32:40,120 --> 02:32:42,120
PRESENTED AT OUR MAY COUNCIL

3886
02:32:42,120 --> 02:32:42,440
MEETING.

3887
02:32:42,440 --> 02:32:45,400
WE HAVE A NUMBER OF THEM THAT

3888
02:32:45,400 --> 02:32:46,600
ARE CONTINUING THROUGH AUGUST,

3889
02:32:46,600 --> 02:32:49,440
AND IN JANUARY AND BEYOND AS

3890
02:32:49,440 --> 02:32:52,680
NOTED THEY ARE NOW IN ALL OF OUR

3891
02:32:52,680 --> 02:32:53,120
FUNDING OPPORTUNITY

3892
02:32:53,120 --> 02:32:56,240
ANNOUNCEMENTS WITH THE EXCEPTION

3893
02:32:56,240 --> 02:32:57,440
OF OUR TRAINING ANNOUNCEMENTS

3894
02:32:57,440 --> 02:32:59,720
WHERE WE DON'T THINK IT FITS

3895
02:32:59,720 --> 02:33:00,680
WELL FOR TRAINING.

3896
02:33:00,680 --> 02:33:01,960
THERE ARE DIVERSITY MECHANISMS

3897
02:33:01,960 --> 02:33:04,120
IN MANY OF THEM.

3898
02:33:04,120 --> 02:33:05,880
SO WE THINK EVALUATION IS AN

3899
02:33:05,880 --> 02:33:06,640
IMPORTANT COMPONENT OF THIS.

3900
02:33:06,640 --> 02:33:09,160
WE WANT TO BE ABLE TO MEASURE

3901
02:33:09,160 --> 02:33:10,840
WHETHER WE ARE MOVING THE NEEDLE

3902
02:33:10,840 --> 02:33:13,520
IN ANY WAY.

3903
02:33:13,520 --> 02:33:15,600
WE HAVE A VERY LARGE EVALUATION

3904
02:33:15,600 --> 02:33:16,440
PLAN.

3905
02:33:16,440 --> 02:33:18,400
I WON'T GO INTO DETAIL BUT I

3906
02:33:18,400 --> 02:33:22,160
THINK YOU'LL SEE WE HAVE

3907
02:33:22,160 --> 02:33:23,000
SHORT-TERM, MEDIUM-TERM,

3908
02:33:23,000 --> 02:33:24,600
LONG-TERM GOALS THAT WE HAVE

3909
02:33:24,600 --> 02:33:25,880
OUTLINED.

3910
02:33:25,880 --> 02:33:28,640
WE HAVE VERY DEFINED METRICS AND

3911
02:33:28,640 --> 02:33:31,280
SO WE'RE MEASURING WHETHER WE

3912
02:33:31,280 --> 02:33:33,560
ARE GETTING -- HAVING AN IMPACT

3913
02:33:33,560 --> 02:33:40,000
IN THE SHORT TERM AND LONG TERM.

3914
02:33:40,000 --> 02:33:41,520
WE DON'T FLOW IF WE'RE GOING TO

3915
02:33:41,520 --> 02:33:43,960
BE ABLE TO MEASURE THE CULTURE

3916
02:33:43,960 --> 02:33:44,600
CHANGE, MAYBE FOR BRAIN

3917
02:33:44,600 --> 02:33:46,240
INITIATIVE BECAUSE WE'RE SUCH A

3918
02:33:46,240 --> 02:33:47,640
TIGHT GROUP AND WE CAN CONTROL

3919
02:33:47,640 --> 02:33:49,960
LOADS OF THINGS IN OUR FUNDING

3920
02:33:49,960 --> 02:33:50,760
ANNOUNCEMENTS BUT THERE'S SO

3921
02:33:50,760 --> 02:33:52,240
MUCH GOING ON IT'S NOT CLEAR WE

3922
02:33:52,240 --> 02:33:54,800
WOULD BE ABLE TO ATTRIBUTE ANY

3923
02:33:54,800 --> 02:33:56,640
CULTURE CHANGE TO THE PEDP

3924
02:33:56,640 --> 02:33:57,000
SPECIFICALLY.

3925
02:33:57,000 --> 02:34:01,760
WE'RE HOPING TO SEE OUR OWN

3926
02:34:01,760 --> 02:34:02,360
DATA, OWN DEMOGRAPHIC DATA

3927
02:34:02,360 --> 02:34:07,360
CHANGE AS A RESULT OF THIS

3928
02:34:07,360 --> 02:34:07,680
PROGRAM.

3929
02:34:07,680 --> 02:34:10,320
SO IN CONCLUSION DIVERSITY AND

3930
02:34:10,320 --> 02:34:12,280
INCLUSIVITY ARE INTEGRAL TO

3931
02:34:12,280 --> 02:34:12,920
ENHANCING SCIENCE AND

3932
02:34:12,920 --> 02:34:13,800
INNOVATION, WE FEEL THAT

3933
02:34:13,800 --> 02:34:16,120
STRONGLY IN THE BRAIN

3934
02:34:16,120 --> 02:34:19,640
INITIATIVE, REQUIRES CONCERTED

3935
02:34:19,640 --> 02:34:22,600
EFFORT, INTENTIONAL EFFORT TO

3936
02:34:22,600 --> 02:34:23,600
CREATE RESEARCH ENVIRONMENTS,

3937
02:34:23,600 --> 02:34:25,560
AND HOPEFULLY NOW YOU UNDERSTAND

3938
02:34:25,560 --> 02:34:27,600
WE'RE COMMITTED AS AN INITIATIVE

3939
02:34:27,600 --> 02:34:29,280
AND WITH THE SUPPORT OF THE

3940
02:34:29,280 --> 02:34:31,680
STAFF AND LEADERSHIP AS WELL AS

3941
02:34:31,680 --> 02:34:33,120
APPLICANT AND GRANTEE COMMUNITY

3942
02:34:33,120 --> 02:34:35,960
WE'VE HAD SOME REALLY POSITIVE

3943
02:34:35,960 --> 02:34:37,000
FEEDBACK.

3944
02:34:37,000 --> 02:34:41,920
I WANT TO THANK PEOPLE, DR.

3945
02:34:41,920 --> 02:34:43,520
RICHARDSON AND CRAWFORD IN

3946
02:34:43,520 --> 02:34:45,800
PARTICULAR FOR THIS OF THE

3947
02:34:45,800 --> 02:34:47,320
SLIDES GENERATED FOR ME HERE,

3948
02:34:47,320 --> 02:34:53,160
RYAN IS AN INTEGRAL PART OF

3949
02:34:53,160 --> 02:34:55,360
THIS, DEVIN COLLECTED DATA, SO

3950
02:34:55,360 --> 02:34:57,520
MANY PEOPLE TO LIFT ACROSS NIH

3951
02:34:57,520 --> 02:34:58,800
AND LEADERSHIP.

3952
02:34:58,800 --> 02:35:03,640
VERY HAPPY TO ANSWER ANY

3953
02:35:03,640 --> 02:35:06,480
QUESTIONS OR TAKE COMMENTS OR

3954
02:35:06,480 --> 02:35:06,760
FEEDBACK.

3955
02:35:06,760 --> 02:35:09,360
>> THANK YOU FOR A REALLY

3956
02:35:09,360 --> 02:35:10,480
INFORMATIVE SESSION.

3957
02:35:10,480 --> 02:35:11,960
ARE THERE ANY QUESTIONS?

3958
02:35:11,960 --> 02:35:13,720
WE HAVE TIME FOR JUST A LITTLE

3959
02:35:13,720 --> 02:35:18,520
BIT OF DISCUSSION IF ANYONE HAS

3960
02:35:18,520 --> 02:35:24,760
A QUESTION, HAPPY TO DISCUSS. 

3961
02:35:24,760 --> 02:35:25,040
ALL RIGHT.

3962
02:35:25,040 --> 02:35:27,960
WELL, IF YOU DO HAVE QUESTIONS,

3963
02:35:27,960 --> 02:35:29,800
I THINK YOU KNOW WHERE TO REACH

3964
02:35:29,800 --> 02:35:31,880
US AND WE WOULD BE MORE THAN

3965
02:35:31,880 --> 02:35:35,080
HAPPY TO DISCUSS ANY OF THOSE.

3966
02:35:35,080 --> 02:35:38,160
AS YOU CAN TELL, THE NIDCD IS

3967
02:35:38,160 --> 02:35:40,120
HIGHLY INVESTED IN THE BRAIN

3968
02:35:40,120 --> 02:35:41,320
INITIATIVE, WE REALLY APPRECIATE

3969
02:35:41,320 --> 02:35:44,840
THE PARTNERSHIP OF JOHN AND

3970
02:35:44,840 --> 02:35:46,680
ANDREA, AND EVERYONE ELSE

3971
02:35:46,680 --> 02:35:47,040
INVOLVED.

3972
02:35:47,040 --> 02:35:50,120
AND WE ARE VERY ANXIOUS TO

3973
02:35:50,120 --> 02:35:51,520
LEVERAGE THIS OPPORTUNITY, EVEN

3974
02:35:51,520 --> 02:35:55,560
MORE THAN WE DO ALREADY, SO THIS

3975
02:35:55,560 --> 02:35:59,360
WAS A GREAT DISCUSSION AND VERY,

3976
02:35:59,360 --> 02:36:00,560
VERY INFORMATIVE.

3977
02:36:00,560 --> 02:36:03,560
I THINK THAT WE'RE RUNNING A

3978
02:36:03,560 --> 02:36:04,760
LITTLE BIT LATER.

3979
02:36:04,760 --> 02:36:07,280
OH, YES, THANK YOU TO THE

3980
02:36:07,280 --> 02:36:07,600
INTERPRETERS.

3981
02:36:07,600 --> 02:36:09,440
THE INTERPRETERS REALLY MADE

3982
02:36:09,440 --> 02:36:11,840
THIS MEETING ACCESSIBLE FOR MANY

3983
02:36:11,840 --> 02:36:14,240
AND WE VERY MUCH APPRECIATE YOUR

3984
02:36:14,240 --> 02:36:14,840
EFFORTS.

3985
02:36:14,840 --> 02:36:16,480
AND THANKS TO EVERYONE, BECKY

3986
02:36:16,480 --> 02:36:19,440
AND GINGER AND OUR WHOLE STAFF

3987
02:36:19,440 --> 02:36:21,560
THAT MADE THIS A REALLY

3988
02:36:21,560 --> 02:36:22,760
EXCEPTIONAL MEETING I THINK.

3989
02:36:22,760 --> 02:36:24,320
THANK YOU TO EVERYBODY.

3990
02:36:24,320 --> 02:36:26,640
THANK YOU TO OUR COUNCIL

3991
02:36:26,640 --> 02:36:26,880
MEMBERS.

3992
02:36:26,880 --> 02:36:28,160
AND WE APPRECIATE YOUR WORK

3993
02:36:28,160 --> 02:36:29,600
VERY, VERY MUCH AND LOOK FORWARD

3994
02:36:29,600 --> 02:36:31,800
TO SEEING YOU HOPEFULLY IN

3995
02:36:31,800 --> 02:36:33,360
PERSON IN SEPTEMBER.

3996
02:36:33,360 --> 02:36:35,960
PLEASE REACH OUT FOR ANY

3997
02:36:35,960 --> 02:36:37,120
INFORMATION, ANYTHING THAT WE

3998
02:36:37,120 --> 02:36:39,400
CAN ANSWER FOR YOU.

3999
02:36:39,400 --> 02:36:40,360
SO THANKS TO EVERYONE.

4000
02:36:40,360 --> 02:36:43,160
ALL RIGHT.

4001
02:36:43,160 --> 00:00:00,000
TAKE CARE.