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WELL, GOOD MORNING, EVERYONE.

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WELCOME.

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I'LL CALL THE OPEN SESSION OF

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THE 116th MEETING OF NATIONAL

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ARTHRITIS AND MUSCULOSKELETAL

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SKIN DISEASES TO ORDER.

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COUNCIL MEETINGS ARE OPEN TO THE

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PUBLIC AS REQUIRED BY LAW EXCEPT

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FOR THE REVIEW, DISCUSSION, AND

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EVALUATION OF GRANT APPLICATIONS

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AND RELATED INFORMATION WHICH WE

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ADDRESSED THIS MORNING IN CLOSED

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SESSION.

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I ALSO WANT TO REMIND YOU THIS

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MEETING IS BROADCAST BY NIH

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VIDEOCAST AND IS ALSO BEING

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RECORDED.

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I'M GOING TO TURN THE MEETING

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OVER TO DARREN TO GO OVER

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LOGISTICS.

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>> GOOD MORNING, WELCOME
TO THE

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SESSION OF COUNCIL.

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IF ANY STAFF MEMBER WATCHING ON

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VIDEOCAST HAS URGENT QUESTIONS,

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E-MAIL SHALANDA WELLINGTON, MOST

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OF YOU SHOULD HAVE HER E-MAIL

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ADDRESS AND SHE CAN REFER

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QUESTIONS TO ME.

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WE ENCOURAGE VIEWERS TO SUBMIT

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COMMENTS IN WRITING UP TO 15

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DAYS FOLLOWING THE MEETING,

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NIAMSCOUNCILMAIL@MAIL.NIH.GOV.

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SO WE WILL CERTAINLY LOOK FOR

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ANY COMMENTS THERE.

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ANYONE ON TEAMS MAY SPEAK, BUT

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MAKE SURE YOU MUTE YOUR LINE

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WHEN NOT SPEAKING.

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YOU MAY RAISE YOUR HAND, WE CAN

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CALL ON YOU.

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SHALANDA WILL HELP WITH MEETING

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AND UNMUTING ESPECIALLY WHEN

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TAKING VOTES.

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AS MUCH AS POSSIBLE, KEEP YOUR

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VIDEO ON.

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IF YOU NEED COMPUTER SUPPORT OR

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HELP WITH THE ELECTRONIC COUNCIL

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BOOK CONTACT SHALANDA.

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A NOTICE OF THE COUNCIL MEETING

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WAS PUBLISHED IN THE FEDERAL

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REGISTER, I'LL REMIND BUT

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UPCOMING CONFLICT OF INTEREST

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REPORTING DATES, UPDATES

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REQUESTED IN FEBRUARY, JUNE, AND

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OCTOBER.

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WHEN YOU RECEIVE THE REQUEST,

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PLEASE RESPOND WITHIN 30 DAYS IN

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ORDER TO PARTS NATURE

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COUNCIL-RELATED ACTIVITIES.

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FURTHER INFORMATION REGARDING

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CONFLICT OF INTEREST

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SPECULATIONS ARE INCLUDED AGAIN

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IN THE ELECTRONIC COUNCIL BOOKS.

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MINUTES OF THE SEPTEMBER 17,

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2024, COUNCIL MEETING ARE POSTED

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IN THE ELECTRONIC COUNCIL BOOK.

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THE REPORT OF THE BOARD WHICH

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REVIEWS YOUR INTRAMURAL PROGRAM

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IS ALSO PROVIDED THERE.

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I WOULD FINALLY REMIND YOU OF

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DATES OF FUTURE MEETINGS,

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LOCATED IN THE ELECTRONIC

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COUNCIL BOOK.

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NEXT MEETING WILL BE JUNE 3,

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2025.

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WE'RE SETTING UP AS IN-PERSON OR

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HYBRID MEETING.

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GOING FORWARD HOPING TO PLAN

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SPRING MEETINGS TO BE IN PERSON,

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FALL MEETING HYBRID, WINTER

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MEETING, JANUARY MEETING,

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VIRTUAL.

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WE VERY MUCH APPRECIATE YOUR

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PARTICIPATION.

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PLEASE MAKE SURE THESE DATES

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THAT I'M GOING READ OFF ARE

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AVAILABLE ON YOUR CALENDAR.

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JUNE 3, THEN OCTOBER 14, 2025.

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JANUARY 27, 2026, AND JUNE 2,

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2026.

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ALSO WE'LL BE HAVING -- WE'LL BE

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PUTTING OUT A FEDERAL REGISTER

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NOTICE RELATIVELY SOON, IN

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AUGUST CLOSED SESSION ONLY

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COUNCIL WE ARE STILL LOOKING FOR

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A DATE FOR THAT, BUT ONCE WE

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HAVE IT WE'LL BE INVITING YOU TO

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THAT CLOSED SESSION OF COUNCIL.

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IN GENERAL, I WAS GOING SAY WE

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DID HAVE ORIGINALLY CONCEPT

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CLEARANCE PRESENTATIONS TODAY.

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WE'RE UNABLE TO PRESENT THOSE.

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WE'LL DO THOSE AT THE JUNE

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MEETING INSTEAD.

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IF THERE ARE NO QUESTIONS ABOUT

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THIS INFORMATION, I'M GOING TO

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TURN BACK OVER TO DR. CRISWELL.

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>> OKAY.

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LET ME SHARE MY SCREEN HERE. 

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IT'S NOT SHARING.

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>> IN YOUR DESKTOP.

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>> THERE WE GO.

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CAN YOU SEE THAT NOW?

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>>  YES, WE CAN SEE IT.

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>> GREAT, OKAY.

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AS I BEGIN, AS YOU HAVE READ IN

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THE MEDIA WE HAVE A LOT GOING ON

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THESE DAYS AT NIAMS AND NIH.

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IN MARCH, THE U.S. DEPARTMENT OF

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HEALTH AND HUMAN SERVICES

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ANNOUNCED RESTRUCTURING EFFORT

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WHICH WILL CENTRALIZE THE NIH'S

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PROCUREMENTS, HUMAN RESOURCES,

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AND COMMUNICATIONS ACROSS ITS 27

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INSTITUTES AND CENTERS.

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NIH GRANTS AND FUNDING POLICIES

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ARE EVOLVING AS NIH ALIGNS WITH

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NEW AGENCY PRIORITIES.

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I ENCOURAGE YOU TO CHECK THE NIH

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GRANTS AND FUNDING WEBSITE

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REGULARLY FOR UPDATED

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INFORMATION.

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THIS IS A TIME OF TREMENDOUS

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CHANGE AND WHILE I'M SURE THERE

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ARE MANY QUESTIONS, THINGS ARE

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EVOLVING.

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I APPRECIATE YOUR PATIENCE AS WE

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AT NIH IMPLEMENT CHANGES AS PART

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OF A MAJOR HHS REORGANIZATION.

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AND I LOOK FORWARD TO SHARING

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UPDATES WITH YOU AS ADDITIONAL

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INFORMATION BECOMES AVAILABLE.

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BUT I WANT TO ASSURE YOU THAT

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OUR COMMITMENT TO ADVANCING

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RESEARCH THAT WILL IMPROVE THE

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LIVES OF PEOPLE WITH AUTOIMMUNE,

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BONE, JOINT, MUSCLE, RHEUMATIC

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AND SKIN CONDITIONS REMAINS

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STRONG.

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WE LOOK FORWARD TO CONTINUING

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OUR WORK WITH THE COUNCIL TO

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IDENTIFY AND SUPPORT THE BEST

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SCIENCE IN THESE AREAS AS

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CONSISTENT WITH TH

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ADMINISTRATION'S PRIORITIES.

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I'M GOING TO START BY

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INTRODUCING TWO COUNCIL MEMBERS

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WHO WHILE AT OUR SEPTEMBER

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MEETING WERE NOT FORMALLY

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INTRODUCED AT THAT TIME. 

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MS. SHARON SMITH-TERRY, A

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ORTHOPEDIC RESEARCH SOCIETY,

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EXPERIENCE LEADING PROFESSIONAL

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SOCIETIES WITH SERVICE TO THE

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NEUROCRITICAL CARE SOCIETY AND

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AMERICAN HOSPITAL ASSOCIATION,

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BACKGROUND IN MARKETING,

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COMMITMENT TO COMMUNITY THROUGH

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NUMEROUS VOLUNTEER ACTIVITIES.

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WE ALSO WELCOME DR. MELISSA

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SPENCER, PROFESSOR OF NEUROLOGY

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AT UCLA, SHE STUDIES MECHANISMS

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UNDERLYING GENETICALLY INHERITED

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NEUROMUSCULAR DISEASES SUCH AS

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DUCHENNE MUSCULAR DYSTROPHY AND

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LYNN GIRDLE MUSCULAR

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 DYSTROPHY

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TO DEVELOP TREATMENTS FOR THESE

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CONDITIONS.

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WE'VE INVITED OUTSTANDING

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INVESTIGATORS FROM THE NIAMS

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POOL OF MENTORED K01, K08, K23

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AWARD RECIPIENTS TO PARTICIPATE

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IN THIS COUNCIL MEETING AS AD

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HOC MEMBERS.

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THE IDEA IS FAMILIARIZE THEM

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WITH COUNCIL, ALLOW US TO ATTAIN

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INPUT FROM SCIENTISTS AT AN

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EARLIER CAREER STAGE THAN FULL

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COUNCIL MEMBERS TYPICALLY ARE.

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SO TODAY WE'RE JOINED BY DR.

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SARAH GEBAUER AND KRISTIN

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MORGAN.

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DR. GEBAUER FROM ST. LOUIS

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UNIVERSITY SCHOOL OF MEDICINE,

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INTERESTS OF NEIGHBORHOOD AND

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HEALTH, OSTEOARTHRITIS, USE OF

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ADMINISTRATIVE DATA.

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DR. MORGAN ASSOCIATE  PROFESSOR

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UNIVERSITY OF CONNECTICUT,

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QUANTIFYING JOINT STABILITY,

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HUMAN MOVEMENT, ASSESSING LOWER

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EXTREMITY INJURY RISK.

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I OFFER A WARM WELCOME TO YOU

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BOTH.

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I HOPE THAT YOU WILL PLEASE

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PARTICIPATE IN DISCUSSIONS TODAY

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AND PROVIDE YOUR VALUABLE

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PERSPECTIVES ON ANY OR ALL

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TOPICS WE COVER.

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SO I NOW WANT TO CALL ON COUNCIL

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MEMBERS AND KEY STAFF TO

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INTRODUCE THEMSELVES.

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THIS IS JUST FOR THE VIRTUAL

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PARTICIPANTS.

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AND I THANK YOU AND AM DELIGHTED

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TO SEE ALL OF YOU.

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I'LL STOP SHARING MY SCREEN SO

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WE CAN DO THAT.

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I ALSO WANT TO SAY I HOPE THAT

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THIS BODY NOTICED WE'VE PROVIDED

221
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COPIES OF THE BOARD OF

222
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SCIENTIFIC COUNSELORS REPORT OF

223
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OUR INTRAMURAL RESEARCH PROGRAM

224
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AND TRIENNIAL REPORT FOR

225
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CLINICAL TRIALS IN THE

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ELECTRONIC COUNCIL BOOK.

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WE APPRECIATE YOUR CAREFUL

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REVIEW AND COMMENT ON THESE

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IMPORTANT DOCUMENTS.

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SO LET ME STOP SHARING SO WE CAN

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DO SOME INTRODUCTIONS.

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NOW, IT'S TRICKY HERE IN TEAMS

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BECAUSE I'M NOT SEEING

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EVERYBODY.

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DARREN, ARE YOU IN A POSITION TO

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CALL ON FOLKS ONE AT A TIME TO

237
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INTRODUCE THEMSELVES?

238
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YOU'RE MUTED.

239
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>> YOU'RE STILL SHARING
YOUR

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DESKTOP, LINDSEY.

241
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>> HOW ABOUT THIS.

242
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IS THAT BETTER?

243
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>>  YES, THAT'S BETTER.

244
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>> OKAY.

245
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>> I'M GOING TO GO ACROSS
AS I

246
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SEE FOLKS IN THE VIDEO SO I HOPE

247
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THE COUNSELORS HAVE THEIR VIDEO

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ON.

249
00:09:47,333 --> 00:09:52,071
LET ME TURN THAT OFF. 

250
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LET'S START WITH ED. 

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>> GOOD MORNING, ED
BOATWAY,

252
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GEORGIA TECH AND EMORY

253
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UNIVERSITY, RESEARCH AREA IN

254
00:10:03,749 --> 00:10:07,253
RESOLUTION PATHWAYS AND ROLE IN

255
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WOUND HEALING AND

256
00:10:08,621 --> 00:10:11,624
MUSCULOSKELETAL SYSTEM.

257
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>> THANK YOU.

258
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DR. MORGAN.

259
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>> YES, DR. KRISTIN
MORGAN,

260
00:10:15,795 --> 00:10:18,764
FACULTY MEMBER AT THE UNIVERSITY

261
00:10:18,764 --> 00:10:20,499
OF CONNECTICUT, BIOMARKER

262
00:10:20,499 --> 00:10:21,600
ENGINEERING, HUMAN MOVEMENT

263
00:10:21,600 --> 00:10:23,569
RESEARCH AND DEVELOPING NOVEL

264
00:10:23,569 --> 00:10:25,071
REHABILITATION PROTOCOLS AND

265
00:10:25,071 --> 00:10:28,040
OPTIMIZING MOVEMENT PATTERNS

266
00:10:28,040 --> 00:10:30,976
THROUGH COMPUTATIONAL MODELING.

267
00:10:30,976 --> 00:10:33,212
>> THANK YOU.

268
00:10:33,212 --> 00:10:33,579
DOUG KIEL?

269
00:10:33,579 --> 00:10:34,714
>>  HI THERE.

270
00:10:34,714 --> 00:10:38,250
I AM A PROFESSOR OF MEDICINE AT

271
00:10:38,250 --> 00:10:40,953
HARVARD MEDICAL SCHOOL, SENIOR

272
00:10:40,953 --> 00:10:43,923
SCIENTIST AT THE MARCUS

273
00:10:43,923 --> 00:10:47,960
INSTITUTE FOR AGING INSTITUTE IN

274
00:10:47,960 --> 00:10:48,627
BOSTON.

275
00:10:48,627 --> 00:10:52,665
MY RESEARCH FOCUSES ON

276
00:10:52,665 --> 00:10:53,933
MULTI-OMICS AND MUSCULOSKELETAL

277
00:10:53,933 --> 00:10:55,601
DISEASE, CLINICAL TRIALS, AND

278
00:10:55,601 --> 00:10:59,839
THE AGING OF THE MUSCULOSKELETAL

279
00:10:59,839 --> 00:11:00,072
SYSTEM.

280
00:11:00,072 --> 00:11:01,006
>> THANK YOU.

281
00:11:01,006 --> 00:11:02,875
AND MY APOLOGIES FOR MOVING BACK

282
00:11:02,875 --> 00:11:11,484
AND FORTH BETWEEN FIRST NAMES,

283
00:11:11,484 --> 00:11:13,919
IT DEPENDS HOW LONG I'VE KNOWN

284
00:11:13,919 --> 00:11:14,120
FOLKS.

285
00:11:14,120 --> 00:11:18,157
STEPHEN, I THINK I'VE KNOWN YOU

286
00:11:18,157 --> 00:11:18,958
LONG ENOUGH.

287
00:11:18,958 --> 00:11:20,159
>> THANKS, DARREN.

288
00:11:20,159 --> 00:11:22,795
STEPHEN TAYLOR, PRESIDENT AND

289
00:11:22,795 --> 00:11:23,429
CEO ARTHRITIS FOUNDATION,

290
00:11:23,429 --> 00:11:24,063
REPRESENTING 60 MILLION ADULTS,

291
00:11:24,063 --> 00:11:24,964
HOUSE OF REPRESENTATIVES OF

292
00:11:24,964 --> 00:11:27,399
THOUSANDS OF CHILDREN WITH

293
00:11:27,399 --> 00:11:29,401
ARTHRITIS, VARIOUS FORMS,

294
00:11:29,401 --> 00:11:35,608
HONORED TO BE HERE TODAY.

295
00:11:35,608 --> 00:11:41,547
>> THANK YOU. 

296
00:11:41,547 --> 00:11:44,984
AND ANN ELDERKIN.

297
00:11:44,984 --> 00:11:46,152
>> FORMER MANAGER,
MANAGING

298
00:11:46,152 --> 00:11:47,386
EDITOR OF SURGEON GENERAL'S

299
00:11:47,386 --> 00:11:51,390
REPORT ON BONE HEALTH AND

300
00:11:51,390 --> 00:11:51,724
OSTEOPOROSIS.

301
00:11:51,724 --> 00:11:53,726
PLEASURE TO BE HERE.

302
00:11:53,726 --> 00:12:01,367
>> THANK YOU.

303
00:12:01,367 --> 00:12:02,701
MELISSA SPENCER.

304
00:12:02,701 --> 00:12:03,102
>> SORRY.

305
00:12:03,102 --> 00:12:04,537
DR. CRISWELL ALREADY DID GIVE

306
00:12:04,537 --> 00:12:06,172
SOME BACKGROUND BUT I'M REALLY

307
00:12:06,172 --> 00:12:09,041
HAPPY TO BE HERE, MELISSA

308
00:12:09,041 --> 00:12:11,877
SPENCER, PROFESSOR OF NEUROLOGY,

309
00:12:11,877 --> 00:12:14,580
I'M ALSO THE DIRECTOR OF THE

310
00:12:14,580 --> 00:12:15,381
NEUROMUSCULAR PROGRAM IN

311
00:12:15,381 --> 00:12:19,585
DEPARTMENT OF NEUROLOGY AT UCLA.

312
00:12:19,585 --> 00:12:22,721
I'VE DONE BASIC SCIENCE IN

313
00:12:22,721 --> 00:12:25,457
MUSCLE, MUSCLE BIOLOGY, AS WELL

314
00:12:25,457 --> 00:12:27,326
AS TRANSLATIONAL RESEARCH AND

315
00:12:27,326 --> 00:12:28,828
CLINICAL TRIALS IN UNDERSTANDING

316
00:12:28,828 --> 00:12:31,363
PATHOGENESIS AND DEVELOPING

317
00:12:31,363 --> 00:12:36,735
THERAPIES FOR THESE DISEASES.

318
00:12:36,735 --> 00:12:39,572
>> THANK YOU.

319
00:12:39,572 --> 00:12:41,907
DR. SMITH TERRY.

320
00:12:41,907 --> 00:12:44,076
>> HELLO, SHARON SMITH
TERRY,

321
00:12:44,076 --> 00:12:45,611
CEO OF ORTHOPEDIC RESEARCH

322
00:12:45,611 --> 00:12:48,013
SOCIETY, WE'RE THE LEADING

323
00:12:48,013 --> 00:12:52,718
RESEARCH SOCIETY GLOBALLY THAT

324
00:12:52,718 --> 00:12:53,953
DOES RESEARCH IN

325
00:12:53,953 --> 00:12:54,920
MULTI-DISCIPLINARY AREAS OF MSK,

326
00:12:54,920 --> 00:12:58,557
SO HAPPY TO BE HERE.

327
00:12:58,557 --> 00:13:02,261
>> THANK YOU.

328
00:13:02,261 --> 00:13:03,229
DR. GEBAUER.

329
00:13:03,229 --> 00:13:05,865
>> HI, SARAH GEBAUER,
FAMILY

330
00:13:05,865 --> 00:13:06,866
SUGGESTION, TRANSLATIONAL

331
00:13:06,866 --> 00:13:07,366
EPIDEMIOLOGIST ST. LOUIS

332
00:13:07,366 --> 00:13:08,701
UNIVERSITY SCHOOL OF MEDICINE,

333
00:13:08,701 --> 00:13:10,002
ST. LOUIS, MISSOURI.

334
00:13:10,002 --> 00:13:11,670
RESEARCH IS FOCUSED ON THE

335
00:13:11,670 --> 00:13:13,038
INTERSECTION OF ADMINISTRATIVE

336
00:13:13,038 --> 00:13:14,106
HEALTH DATA LIKE ELECTRONIC

337
00:13:14,106 --> 00:13:15,507
HEALTH RECORD DATA AND

338
00:13:15,507 --> 00:13:16,408
GEOSPATIAL INFORMATION SCIENCE

339
00:13:16,408 --> 00:13:18,344
SO WE CAN BETTER UNDERSTAND HOW

340
00:13:18,344 --> 00:13:19,812
THE MILIEU THAT SOMEONE LIVES

341
00:13:19,812 --> 00:13:22,281
IN, WORKS, IN GROWS UP IN, MAY

342
00:13:22,281 --> 00:13:24,283
IMPACT SOMEONE'S IN THIS CASE

343
00:13:24,283 --> 00:13:25,684
PREVALENCE OF OSTEOARTHRITIS OR

344
00:13:25,684 --> 00:13:27,887
TRAJECTORY IN TERMS OF TREATMENT

345
00:13:27,887 --> 00:13:32,157
AND THERAPIES.

346
00:13:32,157 --> 00:13:33,459
>> THANK YOU.

347
00:13:33,459 --> 00:13:33,659
CARL?

348
00:13:33,659 --> 00:13:37,630
>>  GOOD MORNING,
EVERYONE. 

349
00:13:37,630 --> 00:13:40,132
CARL JUSTIN, ASSOCIATE DEAN FOR

350
00:13:40,132 --> 00:13:41,233
RESEARCH, U OF M SCHOOL OF

351
00:13:41,233 --> 00:13:44,103
MEDICINE, AREA OF RESEARCH IS IN

352
00:13:44,103 --> 00:13:45,604
COMPLEX ADAPTIVE SYSTEMS, I

353
00:13:45,604 --> 00:13:50,009
STUDY BONE PRIMARILY TO IDENTIFY

354
00:13:50,009 --> 00:13:52,511
EARLY INDICATORS OF FRAGILITY.

355
00:13:52,511 --> 00:14:00,519
THANK YOU. 

356
00:14:00,519 --> 00:14:04,023
>> THANK YOU. 

357
00:14:04,023 --> 00:14:05,224
>> BECKY MINNILLO.

358
00:14:05,224 --> 00:14:06,525
>> CONDUCTING SKIN
RESEARCH,

359
00:14:06,525 --> 00:14:09,295
GLAD TO BE HERE.

360
00:14:09,295 --> 00:14:12,031
>> BETH McNALLY.

361
00:14:12,031 --> 00:14:13,699
>> BETH McNALLY,
NORTHWESTERN

362
00:14:13,699 --> 00:14:14,967
UNIVERSITY STEINBERG SCHOOL OF

363
00:14:14,967 --> 00:14:16,001
MEDICINE, PHYSICIAN AND

364
00:14:16,001 --> 00:14:17,569
SCIENTIST, LEAD OUR CENTER FOR

365
00:14:17,569 --> 00:14:24,910
GENETIC MEDICINE, AS LONG AS --

366
00:14:24,910 --> 00:14:31,483
LONG STAND HAVING IN MUSCULAR

367
00:14:31,483 --> 00:14:32,484
DYSTROPHIES, INTERESTED IN

368
00:14:32,484 --> 00:14:34,853
MODIFIERS AND THERAPIES.

369
00:14:34,853 --> 00:14:37,056
>> THANK YOU.

370
00:14:37,056 --> 00:14:37,356
AIMEE PAYNE

371
00:14:37,356 --> 00:14:39,425
>> AIMEE PAYNE, PROFESSOR
AND

372
00:14:39,425 --> 00:14:41,360
CHAIR OF DERMATOLOGY, COLUMBIA

373
00:14:41,360 --> 00:14:45,097
UNIVERSITY, PRESIDENT OF SOCIETY

374
00:14:45,097 --> 00:14:46,131
FOR INVESTIGATIVE DERMATOLOGY,

375
00:14:46,131 --> 00:14:55,641
MECHANISMS AND TREATMENT OF

376
00:14:55,641 --> 00:14:58,277
AUTOIMMUNITY, PARTICULARLY

377
00:14:58,277 --> 00:15:00,346
CELLULAR THERAPIES.

378
00:15:00,346 --> 00:15:01,547
>> CHIEF OF DIVISION OF

379
00:15:01,547 --> 00:15:02,748
RHEUMATOLOGY, SAN FRANCISCO

380
00:15:02,748 --> 00:15:05,718
GENERAL, PROFESSOR OF MEDICINE

381
00:15:05,718 --> 00:15:07,486
AT UCSF, I STUDY EPIDEMIOLOGY

382
00:15:07,486 --> 00:15:11,423
AND OUTCOMES OF RUMOR MATTIC

383
00:15:11,423 --> 00:15:13,692
DISEASES. 

384
00:15:13,692 --> 00:15:14,159
>> THANK YOU.

385
00:15:14,159 --> 00:15:18,197
AND DR. LEE.

386
00:15:18,197 --> 00:15:20,366
>> HI, I'M A STAFF
PROFESSOR

387
00:15:20,366 --> 00:15:24,236
FROM DEPARTMENT OF BIOMARKER

388
00:15:24,236 --> 00:15:27,706
ENGINEERING, DIRECTOR OF THE

389
00:15:27,706 --> 00:15:31,110
PROGRAM OF ADVANCED

390
00:15:31,110 --> 00:15:31,710
MUSCULOSKELETAL IMAGING

391
00:15:31,710 --> 00:15:35,280
CLEVELAND LYNNIC, RESEARCH ON

392
00:15:35,280 --> 00:15:36,048
BIOTECHNICAL DEVELOPMENTS AND

393
00:15:36,048 --> 00:15:41,854
CLINICAL TRANSLATION OF IMAGING

394
00:15:41,854 --> 00:15:44,156
FOR DISORDERS TO IMPROVE EARLY

395
00:15:44,156 --> 00:15:45,124
DIAGNOSIS AND PROGNOSIS.

396
00:15:45,124 --> 00:15:47,860
A PLEASURE AND HONOR TO BE HERE.

397
00:15:47,860 --> 00:15:48,727
THANK YOU.

398
00:15:48,727 --> 00:15:49,628
>> THANK YOU.

399
00:15:49,628 --> 00:15:53,465
I THINK WE GOT ALL OF OUR

400
00:15:53,465 --> 00:15:54,099
COUNSELORS.

401
00:15:54,099 --> 00:15:55,534
LET ME HAVE SOME OF THE STAFF

402
00:15:55,534 --> 00:15:57,870
WHO ARE NOT IN THE ROOM WITH ME

403
00:15:57,870 --> 00:16:04,309
INTRODUCE THEMSELVES.

404
00:16:04,309 --> 00:16:08,680
I'LL START WITH ANNA.

405
00:16:08,680 --> 00:16:10,315
>> ANNA MIZUKO, DEPUTY
DIRECTOR,

406
00:16:10,315 --> 00:16:11,417
LINDSEY WILL INTRODUCE THAT IN A

407
00:16:11,417 --> 00:16:12,951
LITTLE BIT BUT IT'S REALLY GREAT

408
00:16:12,951 --> 00:16:16,655
TO MEET YOU ALL TODAY.

409
00:16:16,655 --> 00:16:20,726
THANKS SO MUCH.

410
00:16:20,726 --> 00:16:23,996
>> AND TAMARA.

411
00:16:23,996 --> 00:16:25,064
>> TAMARA ELLISON, NEW

412
00:16:25,064 --> 00:16:25,964
SCIENTIFIC DIRECTOR, I'LL SHARE

413
00:16:25,964 --> 00:16:26,965
MORE LATER.

414
00:16:26,965 --> 00:16:30,803
GREAT TO BE WITH YOU TODAY.

415
00:16:30,803 --> 00:16:31,770
>> AND WE HAVE A LOT OF
PEOPLE

416
00:16:31,770 --> 00:16:32,304
IN THE ROOM.

417
00:16:32,304 --> 00:16:34,807
I'LL CALL ON A COUPLE TO

418
00:16:34,807 --> 00:16:37,242
INTRODUCE THEMSELVES.

419
00:16:37,242 --> 00:16:43,916
TO MY RIGHT GAIL. 

420
00:16:43,916 --> 00:16:45,350
>> GAYLE LESTER, DIRECTOR
OF

421
00:16:45,350 --> 00:16:47,453
EXTRAMURAL RESEARCH.

422
00:16:47,453 --> 00:16:47,786
>> AND MARY?

423
00:16:47,786 --> 00:16:52,791
>> HELLO, GOOD MORNING. 

424
00:16:52,791 --> 00:17:03,202
YES, GOOD MORNING STILL.

425
00:17:03,669 --> 00:17:07,539
>> BOB CARTER IS ON.

426
00:17:07,539 --> 00:17:09,675
WOULD LOVE TO --

427
00:17:09,675 --> 00:17:13,112
>> GOOD MORNING, BOB
CARTER,

428
00:17:13,112 --> 00:17:15,013
EX-DEPUTY DIRECTOR, AND NOW

429
00:17:15,013 --> 00:17:17,182
ADVISING LINDSEY ON THE VARIOUS

430
00:17:17,182 --> 00:17:19,251
PROJECTS GOING ON AND TRYING TO

431
00:17:19,251 --> 00:17:21,987
FIGURE OUT HOW TO NAVIGATE IN

432
00:17:21,987 --> 00:17:29,661
THE CURRENT CONTEXT.

433
00:17:29,661 --> 00:17:31,196
THANKS.

434
00:17:31,196 --> 00:17:33,265
>> I THINK WE'RE OKAY.

435
00:17:33,265 --> 00:17:34,666
>> LET ME -- IF THERE ARE
OTHERS

436
00:17:34,666 --> 00:17:35,767
WHO WOULD LIKE TO INTRODUCE

437
00:17:35,767 --> 00:17:38,504
THEMSELVES OR IF QUESTIONS COME

438
00:17:38,504 --> 00:17:40,906
UP AND PROGRAM OFFICERS SPEAK UP

439
00:17:40,906 --> 00:17:41,773
PLEASE INTRODUCE YOURSELF IF WE

440
00:17:41,773 --> 00:17:42,541
HAVEN'T DONE SO.

441
00:17:42,541 --> 00:17:45,410
IF ANYBODY ELSE WOULD LIKE TO

442
00:17:45,410 --> 00:17:54,520
SAY HELLO PLEASE FEEL FREE.

443
00:17:54,520 --> 00:17:56,488
AND IF NOT, I THINK I'LL GO BACK

444
00:17:56,488 --> 00:17:58,257
TO MY SLIDES.

445
00:17:58,257 --> 00:17:59,858
FORGIVE ME FOR A MINUTE.

446
00:17:59,858 --> 00:18:02,261
JUST LET ME GET THIS BACK UP

447
00:18:02,261 --> 00:18:08,300
AGAIN. 

448
00:18:08,300 --> 00:18:15,607
OKAY, CAN YOU SEE IT AGAIN? 

449
00:18:15,607 --> 00:18:15,741
 

450
00:18:15,741 --> 00:18:16,008
>> YES.

451
00:18:16,008 --> 00:18:19,344
>> OKAY, GREAT.

452
00:18:19,344 --> 00:18:21,780
SO, MY REPORT TODAY IS GOING TO

453
00:18:21,780 --> 00:18:23,215
FOCUS ON THREE TOPICS.

454
00:18:23,215 --> 00:18:27,152
FIRST I'LL COVER SOME PERSONNEL

455
00:18:27,152 --> 00:18:28,153
CHANGES AT THE DEPARTMENT OF

456
00:18:28,153 --> 00:18:30,289
HEALTH AND HUMAN SERVICES, NIH

457
00:18:30,289 --> 00:18:32,191
AND NIAMS.

458
00:18:32,191 --> 00:18:34,359
THEN I'LL TOUCH UPON NIH AND

459
00:18:34,359 --> 00:18:36,328
NIAMS BUDGET AND SHARE NIH AND

460
00:18:36,328 --> 00:18:39,831
NIAMS ACTIVITIES THAT MAY BE OF

461
00:18:39,831 --> 00:18:41,567
GENERAL INTEREST.

462
00:18:41,567 --> 00:18:43,435
SO, I'LL START BY ANNOUNCING

463
00:18:43,435 --> 00:18:45,170
LEADERSHIP UPDATES I'M SURE YOU

464
00:18:45,170 --> 00:18:48,340
ARE AWARE OF FROM THE NEWS.

465
00:18:48,340 --> 00:18:52,277
BUT ON FEBRUARY 13, MR. ROBERT

466
00:18:52,277 --> 00:18:56,448
F. KENNEDY JR. WAS SWORN IN AS

467
00:18:56,448 --> 00:18:58,984
26th SECRETARY, FOLLOWING

468
00:18:58,984 --> 00:19:00,052
NOMINATION BY PRESIDENT TRUMP

469
00:19:00,052 --> 00:19:03,121
AND CONFIRMATION BY U.S. SENATE.

470
00:19:03,121 --> 00:19:06,658
SECRETARY MR. KENNEDY WILL

471
00:19:06,658 --> 00:19:09,294
OVERSEE ALL HHS PROGRAMS

472
00:19:09,294 --> 00:19:13,098
OPERATING DIVISIONS AND

473
00:19:13,098 --> 00:19:14,433
ACTIVITIES INCLUDING NIH.

474
00:19:14,433 --> 00:19:17,736
AFTER GRADUATING FROM HARVARD

475
00:19:17,736 --> 00:19:19,137
STUDIED AT LONDON SCHOOL OF

476
00:19:19,137 --> 00:19:20,138
ECONOMICS, LAW DEGREE FROM

477
00:19:20,138 --> 00:19:22,674
UNIVERSITY OF VIRGINIA LAW

478
00:19:22,674 --> 00:19:25,177
SCHOOL, ALSO HOLDS MASTER DEGREE

479
00:19:25,177 --> 00:19:27,246
IN ENVIRONMENTAL LAW FROM PACE

480
00:19:27,246 --> 00:19:31,850
UNIVERSITY SCHOOL OF LAW. 

481
00:19:31,850 --> 00:19:36,321
SHIFTING NOW TO NIH, JAY

482
00:19:36,321 --> 00:19:38,290
BHATTACHARYA STARTED ON APRIL 1

483
00:19:38,290 --> 00:19:40,259
OF THIS YEAR, PRESIDENT TRUMP

484
00:19:40,259 --> 00:19:43,695
NOMINATED HIM FOR THE POSITION

485
00:19:43,695 --> 00:19:46,265
ON NOVEMBER 26 OF 2024, AND U.S.

486
00:19:46,265 --> 00:19:49,868
SENATE CONFIRMED HIM ON MARCH

487
00:19:49,868 --> 00:19:51,203
25, 2025.

488
00:19:51,203 --> 00:19:52,738
HE PREVIOUSLY HELD A TENURED

489
00:19:52,738 --> 00:19:54,740
PROFESSORSHIP IN MEDICAL SCHOOL

490
00:19:54,740 --> 00:19:56,375
AT STANFORD UNIVERSITY IN

491
00:19:56,375 --> 00:19:56,708
CALIFORNIA.

492
00:19:56,708 --> 00:19:59,444
AND HIS RESEARCH FOCUSED ON

493
00:19:59,444 --> 00:20:01,747
POPULATION AGING, AND CHRONIC

494
00:20:01,747 --> 00:20:04,349
DISEASE, PARTICULARLY HEALTH AND

495
00:20:04,349 --> 00:20:06,785
WELL-BEING OF VULNERABLE

496
00:20:06,785 --> 00:20:07,219
POPULATIONS.

497
00:20:07,219 --> 00:20:07,986
BEFORE JOINING STANFORD, HE

498
00:20:07,986 --> 00:20:09,755
CONDUCTED RESEARCH AT THE

499
00:20:09,755 --> 00:20:11,923
NATIONAL BUREAU OF ECONOMIC

500
00:20:11,923 --> 00:20:13,592
RESEARCH AND SPHERE INSTITUTE, A

501
00:20:13,592 --> 00:20:15,994
POLICY RESEARCH FIRM.

502
00:20:15,994 --> 00:20:20,132
HE WAS ALSO AN ECONOMIST AT RAND

503
00:20:20,132 --> 00:20:21,767
CORPORATION, VISITING ECONOMICS

504
00:20:21,767 --> 00:20:24,736
PROFESSOR AT UCLA IN LOS

505
00:20:24,736 --> 00:20:25,170
ANGELES.

506
00:20:25,170 --> 00:20:28,240
HE EARNED A BACHELOR'S AND

507
00:20:28,240 --> 00:20:31,343
MASTER'S DEGREES IN ECONOMICS

508
00:20:31,343 --> 00:20:32,210
FROM STANFORD, COMPLETED MEDICAL

509
00:20:32,210 --> 00:20:34,880
SCHOOL AND EARNED A Ph.D. IN

510
00:20:34,880 --> 00:20:37,549
ECONOMICS ALSO FROM STANFORD

511
00:20:37,549 --> 00:20:38,083
UNIVERSITY.

512
00:20:38,083 --> 00:20:39,651
AND MOVING CLOSER TO HOME I'M

513
00:20:39,651 --> 00:20:41,386
PLEASED TO ANNOUNCE NIAMS HAS A

514
00:20:41,386 --> 00:20:46,758
NEW DEPUTY DIRECTOR, WHO YOU

515
00:20:46,758 --> 00:20:57,035
JUST MET, DR. ANNA MAZZUCCO,

516
00:20:57,035 --> 00:21:00,305
JOINED FROM THE NIH DIVISION OF

517
00:21:00,305 --> 00:21:02,708
PROGRAM COORDINATION PLANNING

518
00:21:02,708 --> 00:21:04,343
AND STRATEGIC INITIATIVES, ALSO

519
00:21:04,343 --> 00:21:06,445
KNOWN AS DPCPSI, AS A SENIOR

520
00:21:06,445 --> 00:21:09,281
ADVISER TO THE DPCPSI DIRECTOR,

521
00:21:09,281 --> 00:21:12,017
AFTER PREVIOUSLY SERVING AS

522
00:21:12,017 --> 00:21:13,752
NIH'S ACTING ASSOCIATE DEPUTY

523
00:21:13,752 --> 00:21:16,521
DIRECTOR IN THE IMMEDIATE OFFICE

524
00:21:16,521 --> 00:21:18,657
OF THE DIRECTOR.

525
00:21:18,657 --> 00:21:21,126
SHE EARNED A Ph.D. FROM

526
00:21:21,126 --> 00:21:23,595
HARVARD MEDICAL SCHOOL, APPLIED

527
00:21:23,595 --> 00:21:26,131
SYSTEMS BIOLOGY APPROACHES TO

528
00:21:26,131 --> 00:21:26,732
UNDERSTANDING MOLECULAR

529
00:21:26,732 --> 00:21:30,535
INTERPLAY BETWEEN CELLULAR AGING

530
00:21:30,535 --> 00:21:35,240
AND GROWTH CONTROL, WORKED AT

531
00:21:35,240 --> 00:21:35,907
NON-PROFIT ORGANIZATION IN

532
00:21:35,907 --> 00:21:36,641
WASHINGTON, D.C. ADDRESSING

533
00:21:36,641 --> 00:21:38,276
WOMEN'S HEALTH AND CLINICAL

534
00:21:38,276 --> 00:21:38,510
TRIALS.

535
00:21:38,510 --> 00:21:40,045
WE'RE DELIGHTED THAT SHE HAS

536
00:21:40,045 --> 00:21:41,480
DECIDED TO MAKE NIAMS HER HOME

537
00:21:41,480 --> 00:21:44,416
FOR THE NEXT PHASE OF HER

538
00:21:44,416 --> 00:21:44,649
CAREER.

539
00:21:44,649 --> 00:21:50,989
AND LET ME STOP SHARING A MOMENT

540
00:21:50,989 --> 00:21:53,558
SO DR. MAZZUCCO CAN OFFER A

541
00:21:53,558 --> 00:21:54,493
COUPLE COMMENTS.

542
00:21:54,493 --> 00:21:56,828
>> THANK YOU.

543
00:21:56,828 --> 00:21:58,463
IT'S REALLY A PLEASURE TO MEET

544
00:21:58,463 --> 00:22:00,632
YOU ALL AND I LOOK FORWARD TO

545
00:22:00,632 --> 00:22:02,300
BEING ABLE TO MEET IN PERSON

546
00:22:02,300 --> 00:22:06,004
WHEN WE'RE ABLE TO DO THAT AND

547
00:22:06,004 --> 00:22:10,409
AS DR. CRISWELL SAID I CAME ON

548
00:22:10,409 --> 00:22:13,245
DETAIL LAST YEAR, AND IT'S JUST

549
00:22:13,245 --> 00:22:14,212
BEEN WITH WONDERFUL TIME GETTING

550
00:22:14,212 --> 00:22:15,547
TO KNOW NIAMS.

551
00:22:15,547 --> 00:22:18,283
I WAS DELIGHTED TO BE ABLE TO

552
00:22:18,283 --> 00:22:22,120
MAKE THIS MY HOME AND I'VE

553
00:22:22,120 --> 00:22:23,288
ENJOYED WORKING WITH LINDSEY AND

554
00:22:23,288 --> 00:22:26,258
BOB AND ALL THE REST OF THE

555
00:22:26,258 --> 00:22:29,261
NIAMS TEAM AND GETTING TO BETTER

556
00:22:29,261 --> 00:22:31,329
KNOW OUR RESEARCH AREAS AND I

557
00:22:31,329 --> 00:22:32,431
JUST REALLY LOOK FORWARD TO

558
00:22:32,431 --> 00:22:33,732
WORKING WITH ALL OF YOU.

559
00:22:33,732 --> 00:22:39,337
SO THANK YOU SO MUCH.

560
00:22:39,337 --> 00:22:40,338
>> AND ANNA'S DEEP
KNOWLEDGE OF

561
00:22:40,338 --> 00:22:41,973
NIH INCLUDING OFFICE OF DIRECTOR

562
00:22:41,973 --> 00:22:43,041
HAS BEEN EXTREMELY VALUABLE

563
00:22:43,041 --> 00:22:44,242
DURING THIS TIME.

564
00:22:44,242 --> 00:22:45,043
THANK YOU.

565
00:22:45,043 --> 00:22:47,279
I'LL GET GOOD AT SHARING AND

566
00:22:47,279 --> 00:22:49,314
UNSHARING IN TEAMS, I CAN SEE.

567
00:22:49,314 --> 00:22:57,389
LET ME GO BACK AND SHARE AGAIN.

568
00:22:57,389 --> 00:22:59,825
HOPEFULLY THAT'S BACK ON.

569
00:22:59,825 --> 00:23:00,225
>> YES.

570
00:23:00,225 --> 00:23:01,793
>> I'M ALSO PLEASED TO
ANNOUNCE

571
00:23:01,793 --> 00:23:04,095
AFTER A HIGHLY COMPETITIVE AND

572
00:23:04,095 --> 00:23:05,730
OPEN SEARCH WE'VE APPOINTED DR.

573
00:23:05,730 --> 00:23:07,732
TAMARA ALLISON AS SCIENTIFIC

574
00:23:07,732 --> 00:23:09,034
DIRECTOR OF NIAMS INTRAMURAL

575
00:23:09,034 --> 00:23:09,935
RESEARCH PROGRAM.

576
00:23:09,935 --> 00:23:12,103
SHE WAS CHOSEN FOR THIS

577
00:23:12,103 --> 00:23:15,607
IMPORTANT ROLE DUE TO

578
00:23:15,607 --> 00:23:17,375
DEMONSTRATED SUCCESS IN

579
00:23:17,375 --> 00:23:19,344
SCIENTIFIC RESEARCH, EXECUTIVE

580
00:23:19,344 --> 00:23:21,079
EXPERIENCE, AND PROGRAMMATIC

581
00:23:21,079 --> 00:23:21,379
LEADERSHIP.

582
00:23:21,379 --> 00:23:28,086
BEFORE JOINING NIAMS, DR.

583
00:23:28,086 --> 00:23:29,721
ALLISTON PROGRESSED AT THE

584
00:23:29,721 --> 00:23:30,822
UNIVERSITY OF CALIFORNIA, SAN

585
00:23:30,822 --> 00:23:31,690
FRANCISCO, MOST RECENTLY AT

586
00:23:31,690 --> 00:23:35,327
PROFESSOR IN DEPARTMENT OF

587
00:23:35,327 --> 00:23:36,528
ORTHOPEDIC SURGERY AT UCSF,

588
00:23:36,528 --> 00:23:38,163
UNDERGRADUATE DEGREE IN BIOLOGY

589
00:23:38,163 --> 00:23:40,799
FROM TRINITY UNIVERSITY IN SAN

590
00:23:40,799 --> 00:23:41,766
ANTONIO, TEXAS, DOCTORAL DEGREE

591
00:23:41,766 --> 00:23:51,276
IN CELL BIOLOGY FROM BAYLOR

592
00:23:51,276 --> 00:23:58,750
COLLEGE OF MEDICINE.

593
00:23:58,750 --> 00:24:00,619
DR. ALLISTON IN INTERESTED IN

594
00:24:00,619 --> 00:24:02,787
DEVELOPING THE NEXT GENERATION

595
00:24:02,787 --> 00:24:06,191
OF SCIENTISTS AND LEADERS, TO

596
00:24:06,191 --> 00:24:07,292
IDENTIFY MULTI-SCALE MECHANISMS

597
00:24:07,292 --> 00:24:09,361
OF SKELETAL DISEASE TO ADVANCE

598
00:24:09,361 --> 00:24:10,328
DEVELOPMENT OF THERAPEUTIC

599
00:24:10,328 --> 00:24:11,429
STRATEGIES.

600
00:24:11,429 --> 00:24:12,964
THIS WORK WILL BUILD ON THE

601
00:24:12,964 --> 00:24:14,633
ACCOMPLISHMENTS OF HER

602
00:24:14,633 --> 00:24:16,601
LABORATORY OVER THE PAST 20

603
00:24:16,601 --> 00:24:18,436
YEARS INVESTIGATING CROSS-TALK

604
00:24:18,436 --> 00:24:22,941
OF BIOCHEMICAL AND PHYSICAL CUES

605
00:24:22,941 --> 00:24:25,110
IN THE SKELETON, DR. ALLISTON

606
00:24:25,110 --> 00:24:31,917
ASSUMES THE ROLE VACATED BY DR.

607
00:24:31,917 --> 00:24:33,718
JOHN O'SHEA, WHO HAS ADDRESSED

608
00:24:33,718 --> 00:24:35,587
THIS COUNCIL BEFORE AND WILL

609
00:24:35,587 --> 00:24:36,955
MAKE IMPORTANT CONTRIBUTIONS TO

610
00:24:36,955 --> 00:24:39,691
NIH THROUGH THE GROUNDBREAKING

611
00:24:39,691 --> 00:24:42,427
WORK OF THE LABORATORY, I THANK

612
00:24:42,427 --> 00:24:43,662
HIM FOR LEADERSHIP AND

613
00:24:43,662 --> 00:24:44,729
SCIENTIFIC ADVANCES BUT NOW

614
00:24:44,729 --> 00:24:50,635
WOULD LIKE TO GIVE DR. ALLISTON

615
00:24:50,635 --> 00:24:52,470
A FEW MOMENTS TO SPEAK WITH YOU.

616
00:24:52,470 --> 00:24:53,805
LET ME STOP SHARING AGAIN.

617
00:24:53,805 --> 00:24:55,006
>> IT'S GREAT TO BE HERE
WITH

618
00:24:55,006 --> 00:24:55,173
YOU.

619
00:24:55,173 --> 00:24:58,410
I AM SO PROUD TO BE A PART OF

620
00:24:58,410 --> 00:24:59,911
THIS NIAMS LEADERSHIP TEAM.

621
00:24:59,911 --> 00:25:02,881
IT'S BEEN WONDERFUL TO WORK WITH

622
00:25:02,881 --> 00:25:06,618
EVERYONE HERE UNDER DR.

623
00:25:06,618 --> 00:25:07,319
CRISWELL'S EXEMPLARY LEADERSHIP,

624
00:25:07,319 --> 00:25:10,655
ESPECIALLY IN THIS TIME OF

625
00:25:10,655 --> 00:25:10,956
TRANSITION.

626
00:25:10,956 --> 00:25:13,258
I'M ALSO PROUD TO FOLLOW ON THE

627
00:25:13,258 --> 00:25:14,593
GREAT WORK DR. O'SHEA HAS

628
00:25:14,593 --> 00:25:17,862
ACCOMPLISHED FOR SO MANY YEARS

629
00:25:17,862 --> 00:25:19,331
LEADING THE INTRAMURAL RESEARCH

630
00:25:19,331 --> 00:25:20,498
PROGRAM AND ITS OUTSTANDING

631
00:25:20,498 --> 00:25:22,133
CADRE OF INVESTIGATORS PUSHING

632
00:25:22,133 --> 00:25:24,469
THE FIELD FORWARD IN

633
00:25:24,469 --> 00:25:26,104
RHEUMATOLOGY, MUSCLE, SKIN, AND

634
00:25:26,104 --> 00:25:27,505
SKELETAL DISEASE, AND I THINK

635
00:25:27,505 --> 00:25:29,040
THAT THE RESEARCH THAT MY TEAM

636
00:25:29,040 --> 00:25:30,375
BRINGS TO THE TABLE WILL

637
00:25:30,375 --> 00:25:34,212
COMPLEMENT THAT AND HELP US TO

638
00:25:34,212 --> 00:25:35,947
BUILD A STRONGER CROSS-NIH

639
00:25:35,947 --> 00:25:42,687
COMMUNITY OF INVESTIGATORS,

640
00:25:42,687 --> 00:25:45,023
ESPECIALLY THINKING, FOLLOWING

641
00:25:45,023 --> 00:25:47,092
WHAT'S HAPPENED IN RHEUMATOLOGY

642
00:25:47,092 --> 00:25:47,993
AND INFLAMMATORY DISEASE,

643
00:25:47,993 --> 00:25:50,095
LOOKING FORWARD TO PARTNERSHIPS

644
00:25:50,095 --> 00:25:50,629
BETWEEN INTRAMURAL AND

645
00:25:50,629 --> 00:25:52,263
EXTRAMURAL RESEARCH AND LOOK

646
00:25:52,263 --> 00:25:53,698
FORWARD TO INTERACTING WITH YOU

647
00:25:53,698 --> 00:25:56,868
IN THIS EXCITING ROLE.

648
00:25:56,868 --> 00:25:59,604
THANK YOU.

649
00:25:59,604 --> 00:26:00,372
>> THANK YOU.

650
00:26:00,372 --> 00:26:02,674
SHE'S BEEN DOING A FABULOUS JOB

651
00:26:02,674 --> 00:26:04,009
DURING VERY UNUSUAL TIMES.

652
00:26:04,009 --> 00:26:14,386
SO THANK YOU SO MUCH.

653
00:26:20,358 --> 00:26:20,492
OKAY.

654
00:26:20,492 --> 00:26:26,431
>> WE MUST CELEBRATE DR.
GALE

655
00:26:26,431 --> 00:26:27,365
LESTER'S PLAN TO RETIRE AT THE

656
00:26:27,365 --> 00:26:37,876
END OF THE MENTHOL CIGARETTES,

657
00:26:39,411 --> 00:26:41,179
 THE -- THE MONTH.

658
00:26:41,179 --> 00:26:43,915
SHE WAS PROGRAM DIRECTOR, SERVED

659
00:26:43,915 --> 00:26:46,551
AS PROJECT OFFICER FOR

660
00:26:46,551 --> 00:26:49,854
OSTEOARTHRITIS INITIATIVE, THE

661
00:26:49,854 --> 00:26:50,755
FIRST NIH PUBLIC/PRIVATE

662
00:26:50,755 --> 00:26:52,057
PARTNERSHIP THROUGH THE

663
00:26:52,057 --> 00:26:54,125
FOUNDATION FOR NIH, SERVES AS

664
00:26:54,125 --> 00:27:00,832
PROJECT DIRECTOR FOR A ANOTHER

665
00:27:00,832 --> 00:27:04,436
FMIH PROJECT, STUDY TO ADVANCE

666
00:27:04,436 --> 00:27:07,472
BMD AS REGULATORY ENDPOINT.

667
00:27:07,472 --> 00:27:11,076
WE'LL MISS HER LEADERSHIP AND

668
00:27:11,076 --> 00:27:12,177
COMMITMENT TO EXCELLENCE.

669
00:27:12,177 --> 00:27:15,346
WHILE WE SEARCH FOR A

670
00:27:15,346 --> 00:27:17,082
REPLACEMENT DR. MARY GARCIA WILL

671
00:27:17,082 --> 00:27:19,517
SERVE AS INTERIM DIRECTOR OF THE

672
00:27:19,517 --> 00:27:19,951
DIVISION.

673
00:27:19,951 --> 00:27:21,720
SEVERAL OF YOU KNOW MARY BECAUSE

674
00:27:21,720 --> 00:27:26,858
SHE'S BEEN WITH NIAMS AS GAYLE'S

675
00:27:26,858 --> 00:27:29,461
DEPUTY SINCE SPRING OF 2023.

676
00:27:29,461 --> 00:27:33,298
SHE WAS AT THE OFFICE OF DISEASE

677
00:27:33,298 --> 00:27:34,399
PREVENTION BEFORE THAT,

678
00:27:34,399 --> 00:27:37,268
SCIENTIFIC ADVISORY TO TOBACCO

679
00:27:37,268 --> 00:27:38,336
REGULATORY PROGRAM SINCE 2014.

680
00:27:38,336 --> 00:27:40,972
THANKS VERY MUCH TO MARY FOR

681
00:27:40,972 --> 00:27:43,041
STEPPING UP AND THANK YOU,

682
00:27:43,041 --> 00:27:46,077
GAYLE, FOR YOUR LEADERSHIP AND

683
00:27:46,077 --> 00:27:46,311
SERVICE.

684
00:27:46,311 --> 00:27:48,513
WE ALSO WELCOME TWO NEW PROGRAM

685
00:27:48,513 --> 00:27:49,380
DIRECTORS WHO JOINED THE

686
00:27:49,380 --> 00:27:52,117
INSTITUTE SINCE OUR LAST

687
00:27:52,117 --> 00:27:53,218
MEETING.

688
00:27:53,218 --> 00:27:55,086
DR. MELISSA PARKER JOINS FROM

689
00:27:55,086 --> 00:27:57,355
OFFICE OF DISEASE PREVENTION,

690
00:27:57,355 --> 00:28:00,325
WHERE SHE SERVED AS SCIENTIFIC

691
00:28:00,325 --> 00:28:10,101
ADVISORY TO OFFICE'S FLAGSHIP

692
00:28:10,101 --> 00:28:13,905
P2P PROGRAM, SHE HAS HELD

693
00:28:13,905 --> 00:28:15,006
SEVERAL POSITIONS AT THE NIH,

694
00:28:15,006 --> 00:28:17,842
INCLUDING A Ph.D. IN

695
00:28:17,842 --> 00:28:19,944
BIOCHEMISTRY AND MOLECULAR

696
00:28:19,944 --> 00:28:24,115
BIOLOGY, FROM INDIANA UNIVERSITY

697
00:28:24,115 --> 00:28:26,851
SCHOOL OF MEDICINE, POSTDOCTORAL

698
00:28:26,851 --> 00:28:28,052
TRAINING AT KANSAS STATE

699
00:28:28,052 --> 00:28:29,587
UNIVERSITY, RESEARCH ASSOCIATE

700
00:28:29,587 --> 00:28:33,958
AT MOREHOUSE SCHOOL OF MEDICINE.

701
00:28:33,958 --> 00:28:42,867
DR. ANITA UNDALE, COMES FROM THE

702
00:28:42,867 --> 00:28:43,535
NATIONAL CANCER INSTITUTE, LIKE

703
00:28:43,535 --> 00:28:46,037
DR. PARKER SHE HAS EXPERIENCE IN

704
00:28:46,037 --> 00:28:49,307
SEVERAL CAPACITIES AT THE NIH,

705
00:28:49,307 --> 00:28:49,874
INCLUDING NIAMS INTRAMURAL

706
00:28:49,874 --> 00:28:53,144
RESEARCH PROGRAM WHERE SHE

707
00:28:53,144 --> 00:28:54,813
WORKED WITH OUR CLINICAL

708
00:28:54,813 --> 00:28:57,582
DIRECTOR DR. BOB COLBERT.

709
00:28:57,582 --> 00:29:01,352
DR. UNDALE OBTAINED M.D. IN

710
00:29:01,352 --> 00:29:03,588
INTERNAL MEDICINE, FELLOWSHIP IN

711
00:29:03,588 --> 00:29:04,989
PATHOLOGY, UNIVERSITY OF MUMBAI

712
00:29:04,989 --> 00:29:08,026
IN INDIA, Ph.D. IN IMMUNOLOGY

713
00:29:08,026 --> 00:29:09,561
FROM MAYO GRADUATE SCHOOL IN

714
00:29:09,561 --> 00:29:11,763
MINNESOTA. 

715
00:29:11,763 --> 00:29:14,499
WELCOME TO YOU BOTH.

716
00:29:14,499 --> 00:29:16,801
NIH IS CURRENTLY OPERATING UNDER

717
00:29:16,801 --> 00:29:19,237
THE FULL YEAR CONTINUING

718
00:29:19,237 --> 00:29:21,339
APPROPRIATIONS AND EXTENSIONS

719
00:29:21,339 --> 00:29:25,777
ACT OF 2025.

720
00:29:25,777 --> 00:29:27,745
REFERRED TO AS HR 1968.

721
00:29:27,745 --> 00:29:30,048
WHICH PRESIDENT SIGNED ON MARCH

722
00:29:30,048 --> 00:29:32,984
15, 2025.

723
00:29:32,984 --> 00:29:36,287
THIS MEANS OUR ENACTED BUDGET

724
00:29:36,287 --> 00:29:39,791
EQUALS COMPARABLE BUDGET ENOUGH

725
00:29:39,791 --> 00:29:41,226
FROM 2024 FISCAL YEAR.

726
00:29:41,226 --> 00:29:42,527
CONSISTENT WITH OUR PREVIOUS

727
00:29:42,527 --> 00:29:43,728
PRACTICE IN RECENT YEARS WE'VE

728
00:29:43,728 --> 00:29:44,929
DECIDED AT THE BEGINNING OF THE

729
00:29:44,929 --> 00:29:47,665
FISCAL YEAR TO SET OUR PAYLINE

730
00:29:47,665 --> 00:29:50,969
AT THE 8th PERCENTILE TO ALLOW

731
00:29:50,969 --> 00:29:52,503
THE INSTITUTE MORE FLEXIBILITY

732
00:29:52,503 --> 00:29:54,806
TO LOOK CRITICALLY AT GRANTS IT

733
00:29:54,806 --> 00:29:55,139
FUNDS.

734
00:29:55,139 --> 00:29:57,075
OUR PROGRAM DIRECTORS WILL

735
00:29:57,075 --> 00:29:59,844
CONTINUE TO SCRUTINIZE THE

736
00:29:59,844 --> 00:30:00,812
MERITORIOUS APPLICATIONS IN

737
00:30:00,812 --> 00:30:03,348
PORTFOLIOS THAT SCORE BEYOND THE

738
00:30:03,348 --> 00:30:04,749
PAYLINE TO IDENTIFY HIGH PRIVATE

739
00:30:04,749 --> 00:30:09,687
PROJECTS FOR THE INSTITUTE TO

740
00:30:09,687 --> 00:30:09,888
FUND.

741
00:30:09,888 --> 00:30:11,956
I'LL START THIS SECTION OF MY

742
00:30:11,956 --> 00:30:15,593
REPORT ABOUT NIH AND NIAMS

743
00:30:15,593 --> 00:30:17,495
ACTIVITIES BY ANNOUNCING FISCAL

744
00:30:17,495 --> 00:30:20,198
YEARS 2025 TO 2029 NIAMS

745
00:30:20,198 --> 00:30:23,034
STRATEGIC PLAN ALONG WITH FACT

746
00:30:23,034 --> 00:30:24,469
SHEET SUMMARY HAS BEEN

747
00:30:24,469 --> 00:30:25,003
PUBLISHED.

748
00:30:25,003 --> 00:30:27,972
AS YOU KNOW THIS PLAN WAS

749
00:30:27,972 --> 00:30:29,140
DRAFTED WITH EXTENSIVE INPUT

750
00:30:29,140 --> 00:30:33,077
FROM YOU AS COUNCIL MEMBERS,

751
00:30:33,077 --> 00:30:39,584
EXTRAMURAL AND INTRAMURAL

752
00:30:39,584 --> 00:30:41,085
RESEARCHERS, HEALTH CARE

753
00:30:41,085 --> 00:30:43,821
ADVOCATES AND PROFESSIONAL

754
00:30:43,821 --> 00:30:44,289
ORGANIZATIONS.

755
00:30:44,289 --> 00:30:45,690
I EXPRESS APPRECIATION FOR THE

756
00:30:45,690 --> 00:30:52,163
HARD WORK THAT WENT INTO

757
00:30:52,163 --> 00:30:55,333
DEVELOPING A STRATEGIC PLAN.

758
00:30:55,333 --> 00:30:58,636
ORGANIZED AROUND FOUR GOALS AND

759
00:30:58,636 --> 00:30:59,237
TEN PRIORITIES REFLECTING THE

760
00:30:59,237 --> 00:31:01,706
DREGS  --

761
00:31:01,706 --> 00:31:03,441
DIRECTION OF THE MISSION.

762
00:31:03,441 --> 00:31:04,776
MANY PRIORITIES ARE ALREADY

763
00:31:04,776 --> 00:31:08,112
BEING PURSUED BY EXTRAMURAL AND

764
00:31:08,112 --> 00:31:10,148
INTRAMURAL RESEARCHERS.

765
00:31:10,148 --> 00:31:11,883
FOR EXAMPLE, I WANT TO

766
00:31:11,883 --> 00:31:13,851
ACKNOWLEDGE AND CONGRATULATE

767
00:31:13,851 --> 00:31:15,586
THREE RESEARCHERS WHO

768
00:31:15,586 --> 00:31:21,592
SUCCESSFULLY COMPETED FOR THE

769
00:31:21,592 --> 00:31:23,027
NIH OFFICE OF AUTOIMMUNE DISEASE

770
00:31:23,027 --> 00:31:25,563
RESEARCH AWARD FOR WORK UNDER

771
00:31:25,563 --> 00:31:27,732
OUR PLAN PRIORITY NUMBER 1,

772
00:31:27,732 --> 00:31:29,167
WHICH STUDY MOLECULAR AND

773
00:31:29,167 --> 00:31:30,468
CELLULAR MECHANISMS OF HEALTH

774
00:31:30,468 --> 00:31:33,104
AND DISEASE IN HUMANS, AND

775
00:31:33,104 --> 00:31:36,174
UNDERSTANDING RESULTING

776
00:31:36,174 --> 00:31:41,646
PHENOTYPES AND ENDOTYPES, USING

777
00:31:41,646 --> 00:31:43,815
AN ESTABLISHES INCLUSIVE AND

778
00:31:43,815 --> 00:31:47,318
WELL PHENOTYPED DATABASE AND

779
00:31:47,318 --> 00:31:48,653
BIOREPOSITORY TO IDENTIFY CD8

780
00:31:48,653 --> 00:31:51,489
POSITIVE T CELLS WHOSE CLONAL

781
00:31:51,489 --> 00:31:54,325
EXPANSION IMPLICATES A

782
00:31:54,325 --> 00:31:58,796
PATHOGENIC CONTRIBUTION TO AXIAL

783
00:31:58,796 --> 00:31:59,897
SPONDYLOARTHRITIS PROGRESSION TO

784
00:31:59,897 --> 00:32:02,200
DEVELOP TESTING TO ENABLE

785
00:32:02,200 --> 00:32:03,968
EARLIER DIAGNOSIS, TOOLS TO

786
00:32:03,968 --> 00:32:05,370
EXPLORE PATHOGENESIS OF DISEASE,

787
00:32:05,370 --> 00:32:09,073
AND IN THE LONGER TERM TO

788
00:32:09,073 --> 00:32:11,175
DEVELOP NOVEL THERAPEUTICS.

789
00:32:11,175 --> 00:32:14,145
DR. NAGAO WILL DISCUSS

790
00:32:14,145 --> 00:32:15,780
INTERACTION OF HUMAN HERPES

791
00:32:15,780 --> 00:32:18,916
VIRUS WITH IMMUNE CELLS IN

792
00:32:18,916 --> 00:32:20,451
CONTEXT OF DRUG INDUCED

793
00:32:20,451 --> 00:32:21,352
HYPERSENSITIVITY SYNDROME.

794
00:32:21,352 --> 00:32:24,622
HIS GOAL TO UNDERSTAND HOW THIS

795
00:32:24,622 --> 00:32:26,591
VIRUS WHEN REACTIVATED IN

796
00:32:26,591 --> 00:32:28,659
CONTEXT OF THE SYNDROME MIGHT

797
00:32:28,659 --> 00:32:30,628
CONTRIBUTE TO BREAKDOWN OF

798
00:32:30,628 --> 00:32:31,229
IMMUNOLOGIC TOLERANCE WHICH

799
00:32:31,229 --> 00:32:35,133
RESULTS IN THE DEVELOPMENT OF

800
00:32:35,133 --> 00:32:36,434
AUTOIMMUNE DISEASE.

801
00:32:36,434 --> 00:32:39,270
OTHER EXCITING NEWS FROM THE NIH

802
00:32:39,270 --> 00:32:40,671
OFFICE OF RESEARCH ON WOMEN'S

803
00:32:40,671 --> 00:32:42,673
HEALTH OF WHICH THE OFFICE OF

804
00:32:42,673 --> 00:32:44,409
AUTOIMMUNE DISEASE RESEARCH IS A

805
00:32:44,409 --> 00:32:48,079
PART INCLUDES AN AWARD CO-FUNDED

806
00:32:48,079 --> 00:32:49,981
BY NIAMS TO COLUMBIA UNIVERSITY

807
00:32:49,981 --> 00:32:53,751
TO OVERSEE THE NEW NEXUS OR

808
00:32:53,751 --> 00:32:55,686
NETWORK FOR EXPOSOMICS IN THE

809
00:32:55,686 --> 00:32:57,555
U.S. COORDINATING CENTER FOR

810
00:32:57,555 --> 00:33:02,827
RESEARCH ON THE HUMAN 

811
00:33:02,827 --> 00:33:04,896
EX-EXPOSOME AND EFFECTS ON

812
00:33:04,896 --> 00:33:07,098
HEALTH REPRESENTING CUMULATIVE

813
00:33:07,098 --> 00:33:08,633
MEASURE OF ENVIRONMENTAL

814
00:33:08,633 --> 00:33:10,268
EXPOSURES AND CORRESPONDING

815
00:33:10,268 --> 00:33:11,069
BIOLOGICAL RESPONSES.

816
00:33:11,069 --> 00:33:13,905
IN ADDITION TO SUPPORTING THE

817
00:33:13,905 --> 00:33:18,509
USE OF EXPOSOMICS ANON NIH

818
00:33:18,509 --> 00:33:19,811
CENTERS NEXUS WILL ENGAGE WITH

819
00:33:19,811 --> 00:33:20,678
ACADEMIC, COMMUNITY AND INDUSTRY

820
00:33:20,678 --> 00:33:22,680
PARTNERS IN THE U.S. AND AROUND

821
00:33:22,680 --> 00:33:23,981
THE WORLD.

822
00:33:23,981 --> 00:33:27,852
IT WILL SUPPORT SCIENTIFIC BOOT

823
00:33:27,852 --> 00:33:28,786
CAMPS, CONFERENCES, OTHER

824
00:33:28,786 --> 00:33:30,955
LEARNING OPPORTUNITIES TO GROW

825
00:33:30,955 --> 00:33:33,391
EXPOSOMICS AS A FIELD WITH

826
00:33:33,391 --> 00:33:37,862
EMPHASIS ON OVERCOMING

827
00:33:37,862 --> 00:33:38,396
SOCIOECONOMIC INEQUITIES.

828
00:33:38,396 --> 00:33:40,364
BEFORE I OPEN THE FLOOR FOR

829
00:33:40,364 --> 00:33:42,667
DISCUSSION, I WANT TO MAKE SURE

830
00:33:42,667 --> 00:33:45,636
YOU'RE AWARE OF TWO NIH-WIDE

831
00:33:45,636 --> 00:33:47,605
POLICY CHANGES.

832
00:33:47,605 --> 00:33:49,907
STARTING THIS PAST JANUARY, MOST

833
00:33:49,907 --> 00:33:51,442
RESEARCH PROJECT GRANT

834
00:33:51,442 --> 00:33:54,278
APPLICATIONS SUBMITTED TO NIH

835
00:33:54,278 --> 00:33:56,347
WILL BE ASSESSED USING

836
00:33:56,347 --> 00:33:58,749
SIMPLIFIED REVIEW CRITERIA THAT

837
00:33:58,749 --> 00:33:59,550
NIH ESTABLISHED TO ADDRESS

838
00:33:59,550 --> 00:34:02,253
COMPLEXITY OF THE PEER REVIEW

839
00:34:02,253 --> 00:34:05,756
PROCESS AND POTENTIAL FOR

840
00:34:05,756 --> 00:34:06,858
REPUTATIONAL BIAS TO AFFECT PEER

841
00:34:06,858 --> 00:34:07,558
REVIEW OUTCOMES.

842
00:34:07,558 --> 00:34:09,260
THESE CHANGES HAVE BEEN IN THE

843
00:34:09,260 --> 00:34:11,596
WORKS FOR SOME TIME, AS THE

844
00:34:11,596 --> 00:34:14,632
CENTER FOR SCIENTIFIC REVIEW

845
00:34:14,632 --> 00:34:17,034
DIRECTOR DR. NONI BYRNES SHARED

846
00:34:17,034 --> 00:34:19,604
AT OUR JUNE 2023 COUNCIL

847
00:34:19,604 --> 00:34:19,837
MEETING.

848
00:34:19,837 --> 00:34:22,740
THE SIMPLIFIED FRAMEWORK FOR NIH

849
00:34:22,740 --> 00:34:26,477
PEER REVIEW CRITERIA RETAINS

850
00:34:26,477 --> 00:34:29,180
FIVE REGULATORY CRITERIA,

851
00:34:29,180 --> 00:34:30,181
SIGNIFICANCE, INVESTIGATORS,

852
00:34:30,181 --> 00:34:31,816
INNOVATION, APPROACH, AND

853
00:34:31,816 --> 00:34:34,218
ENVIRONMENT, BUT REORGANIZES

854
00:34:34,218 --> 00:34:37,288
THEM INTO THREE FACTORS.

855
00:34:37,288 --> 00:34:39,123
TWO WILL RECEIVE NUMERICAL

856
00:34:39,123 --> 00:34:41,325
CRITERION SCORES, ONE OF THE

857
00:34:41,325 --> 00:34:44,595
FACTORS WILL BE EVALUATED SIMPLY

858
00:34:44,595 --> 00:34:45,897
FOR SUFFICIENCY.

859
00:34:45,897 --> 00:34:53,237
ALL THREE FACTORS WILL BE

860
00:34:53,237 --> 00:34:53,538
CONSIDERED.

861
00:34:53,538 --> 00:34:55,006
REFRAMING OF CRITERIA SERVES TO

862
00:34:55,006 --> 00:34:57,175
FOCUS ON THREE CENTRAL QUESTIONS

863
00:34:57,175 --> 00:34:59,010
REVIEWERS SHOULD BE EVALUATING.

864
00:34:59,010 --> 00:35:02,313
HOW IMPORTANT IS THE PROPOSED

865
00:35:02,313 --> 00:35:02,580
RESEARCH?

866
00:35:02,580 --> 00:35:04,415
HOW RIGOROUS AND FEASIBLE ARE

867
00:35:04,415 --> 00:35:05,616
THE METHODS?

868
00:35:05,616 --> 00:35:08,553
AND WHETHER THE INVESTIGATORS

869
00:35:08,553 --> 00:35:10,188
AND INSTITUTIONS HAVE THE

870
00:35:10,188 --> 00:35:10,855
EXPERTISE AND RESOURCES

871
00:35:10,855 --> 00:35:14,125
NECESSARY TO CARRY OUT THE

872
00:35:14,125 --> 00:35:14,525
PROJECT.

873
00:35:14,525 --> 00:35:16,460
OF PARTICULAR NOTE THESE CHANGES

874
00:35:16,460 --> 00:35:18,896
IMPACT HOW AN APPLICATION IS

875
00:35:18,896 --> 00:35:22,133
REVIEWED, THEY DO NOT CHANGE HOW

876
00:35:22,133 --> 00:35:24,101
THE APPLICATION IS DEVELOPED.

877
00:35:24,101 --> 00:35:26,204
REVIEWERS WILL BE PROVIDED

878
00:35:26,204 --> 00:35:28,039
TRAINING AND GUIDANCE MATERIALS

879
00:35:28,039 --> 00:35:30,675
IN THE SPRING OF 2025, IN TIMES

880
00:35:30,675 --> 00:35:34,845
OF FIRST REVIEW MEETINGS THAT

881
00:35:34,845 --> 00:35:38,549
INCLUDE SIMPLIFIED PEER REVIEW

882
00:35:38,549 --> 00:35:40,284
FRAMEWORK IN SUMMER 2025.

883
00:35:40,284 --> 00:35:43,154
YOU LIKELY HEARD ON MARCH 6 NIH

884
00:35:43,154 --> 00:35:44,789
ANNOUNCED PLANS TO CENTRALIZE

885
00:35:44,789 --> 00:35:47,959
PEER REVIEW OF APPLICATIONS

886
00:35:47,959 --> 00:35:51,696
WITHIN THE NIH CENTER FOR

887
00:35:51,696 --> 00:35:53,464
SCIENTIFIC REVIEWERS, CSR.

888
00:35:53,464 --> 00:35:54,966
WE'RE NIAMS APPLICANTS TO OUR

889
00:35:54,966 --> 00:35:57,835
CLINICAL TRIALS NOTICES OF

890
00:35:57,835 --> 00:35:58,436
FUNDING OPPORTUNITIES, CENTER

891
00:35:58,436 --> 00:36:00,438
PROGRAMS, OR A FEW OTHER FUNDING

892
00:36:00,438 --> 00:36:02,974
OPPORTUNITIES, THIS MEANS THAT

893
00:36:02,974 --> 00:36:09,914
THE NIH WILL DISCONTINUE OUR AMS

894
00:36:09,914 --> 00:36:13,484
AND AMAC STUDY COMING TO THE

895
00:36:13,484 --> 00:36:14,585
JUNE COUNCIL.

896
00:36:14,585 --> 00:36:18,422
WE'LL PROVIDE UPDATES ON

897
00:36:18,422 --> 00:36:21,892
CENTRALIZATION EFFORTS AT JUNE

898
00:36:21,892 --> 00:36:22,126
MEETING.

899
00:36:22,126 --> 00:36:25,196
NOW, TO FURTHER NIH'S COMMITMENT

900
00:36:25,196 --> 00:36:26,964
TO PRINCIPLES OF TRANSPARENCY

901
00:36:26,964 --> 00:36:29,033
AND ACCESSIBILITY IN NIH-FUNDED

902
00:36:29,033 --> 00:36:30,901
RESEARCH, NIH RELEASED A NEW

903
00:36:30,901 --> 00:36:33,304
PUBLIC ACCESS POLICY THAT WILL

904
00:36:33,304 --> 00:36:36,040
ACCELERATE BROAD ACCESS TO

905
00:36:36,040 --> 00:36:37,441
NIH-FUNDED RESEARCH RESULTS.

906
00:36:37,441 --> 00:36:39,777
THE MOST SIGNIFICANT CHANGE FROM

907
00:36:39,777 --> 00:36:42,513
THE PREVIOUS POLICY IS REMOVAL

908
00:36:42,513 --> 00:36:46,217
OF THE 12 MONTH EMBARGO PERIOD

909
00:36:46,217 --> 00:36:47,251
BEFORE MANUSCRIPTS RESULTING

910
00:36:47,251 --> 00:36:50,254
FROM NIH FUNDING MUST BE MADE

911
00:36:50,254 --> 00:36:50,688
PUBLICLY AVAILABLE.

912
00:36:50,688 --> 00:36:54,125
IN ADDITION TO THE UPDATED

913
00:36:54,125 --> 00:36:56,927
POLICY, NIH HAS ALSO ISSUED

914
00:36:56,927 --> 00:36:57,695
SUPPLEMENTAL GUIDANCE ON

915
00:36:57,695 --> 00:36:59,230
PUBLICATION COSTS AND ON

916
00:36:59,230 --> 00:37:02,967
GOVERNMENT USE OF LICENSE AND

917
00:37:02,967 --> 00:37:03,200
RIGHTS.

918
00:37:03,200 --> 00:37:05,269
THE UPDATED POLICY AND

919
00:37:05,269 --> 00:37:06,470
SUPPLEMENTAL GUIDANCE WERE

920
00:37:06,470 --> 00:37:07,705
DEVELOPED AFTER CONSIDERED

921
00:37:07,705 --> 00:37:10,308
FEEDBACK THE NIH RECEIVED ON THE

922
00:37:10,308 --> 00:37:12,376
DRAFT PROPOSALS THROUGH A

923
00:37:12,376 --> 00:37:13,911
REQUEST FOR INFORMATION PROCESS.

924
00:37:13,911 --> 00:37:16,013
REVISED POLICY WILL GO INTO

925
00:37:16,013 --> 00:37:19,417
EFFECT FOR PEER REVIEWED

926
00:37:19,417 --> 00:37:22,453
MANUSCRIPT ACCEPTED ON OR AFTER

927
00:37:22,453 --> 00:37:25,189
DECEMBER 31 OF 2025.

928
00:37:25,189 --> 00:37:29,560
UNTIL THAT TIME, NIH'S CURRENT

929
00:37:29,560 --> 00:37:31,228
PUBLIC ACCESS POLICY FROM 2008

930
00:37:31,228 --> 00:37:33,931
WILL REMAIN IN EFFECT.

931
00:37:33,931 --> 00:37:36,567
BROADLY, THE NEW NIH POLICY AIMS

932
00:37:36,567 --> 00:37:38,436
TO MAXIMIZE AND ACCELERATE

933
00:37:38,436 --> 00:37:40,838
ACCESS TO SCIENTIFIC DATA AND

934
00:37:40,838 --> 00:37:43,240
SCHOLARLY ARTICLES RESULTING

935
00:37:43,240 --> 00:37:45,343
FROM FEDERAL FUNDING AND TO MAKE

936
00:37:45,343 --> 00:37:47,411
RESEARCH RESULTS EASIER TO FIND

937
00:37:47,411 --> 00:37:52,016
AND MORE TRANSPARENT BY USING

938
00:37:52,016 --> 00:37:53,984
METADATA AND PERSISTENT

939
00:37:53,984 --> 00:37:54,418
IDENTIFIERS.

940
00:37:54,418 --> 00:37:56,287
SO, I KNOW A LOT IS GOING ON NOW

941
00:37:56,287 --> 00:37:58,456
OUTSIDE OF THE SCOPE OF MY

942
00:37:58,456 --> 00:37:58,689
REMARKS.

943
00:37:58,689 --> 00:38:00,891
BUT I WANT TO OPEN THE FLOOR TO

944
00:38:00,891 --> 00:38:03,728
HEAR WHAT'S ON YOUR MIND WITH

945
00:38:03,728 --> 00:38:04,462
THE UNDERSTANDING THAT MY

946
00:38:04,462 --> 00:38:05,296
ABILITY TO ANSWER QUESTIONS

947
00:38:05,296 --> 00:38:07,231
ABOUT CHANGES THAT ARE DUE TO

948
00:38:07,231 --> 00:38:08,299
ADMINISTRATION OR NIH PRIORITIES

949
00:38:08,299 --> 00:38:10,534
IS LIKELY TO BE LIMITED AT THIS

950
00:38:10,534 --> 00:38:10,968
TIME.

951
00:38:10,968 --> 00:38:19,710
SO THANK YOU FOR YOUR ATTENTION

952
00:38:19,710 --> 00:38:20,611
AND YOUR UNDERSTANDING.

953
00:38:20,611 --> 00:38:23,013
SO LET ME STOP SHARING.

954
00:38:23,013 --> 00:38:23,714
OKAY.

955
00:38:23,714 --> 00:38:25,983
HOPEFULLY YOU'RE NO LONGER

956
00:38:25,983 --> 00:38:31,122
SEEING MY SCREEN.

957
00:38:31,122 --> 00:38:32,423
AND HAPPY TO TAKE QUESTIONS AT

958
00:38:32,423 --> 00:38:42,633
THIS TIME. 

959
00:38:46,971 --> 00:38:48,873
OR I WELCOME COMMENTS FROM MY

960
00:38:48,873 --> 00:38:54,779
COLLEAGUES OR OTHERS ABOUT WHAT

961
00:38:54,779 --> 00:38:55,413
I SHARED.

962
00:38:55,413 --> 00:38:55,613
STEVE?

963
00:38:55,613 --> 00:38:56,514
>> THANKS.

964
00:38:56,514 --> 00:38:58,816
I WANT TO PUBLICLY STATE AGAIN

965
00:38:58,816 --> 00:38:59,817
HOW THE PATIENT COMMUNITY STANDS

966
00:38:59,817 --> 00:39:02,753
WITH NIH AND ALL OF OUR

967
00:39:02,753 --> 00:39:04,822
RESEARCHERS, BOTH INSIDE NIH AS

968
00:39:04,822 --> 00:39:05,923
WELL AS OUTSIDE.

969
00:39:05,923 --> 00:39:08,559
OBVIOUSLY THE WORK THAT WE ALL

970
00:39:08,559 --> 00:39:11,061
DO IS SO IMPORTANT FOR THE

971
00:39:11,061 --> 00:39:12,630
PATIENTS THAT SUFFER FROM

972
00:39:12,630 --> 00:39:13,931
VARIOUS DISEASES NIAMS

973
00:39:13,931 --> 00:39:15,433
REPRESENTS AND TRULY APPRECIATE

974
00:39:15,433 --> 00:39:16,967
YOUR LEADERSHIP WITH ALL THE

975
00:39:16,967 --> 00:39:18,836
AMAZING STAFF AT NIAMS THAT IS

976
00:39:18,836 --> 00:39:20,371
CONTINUING TO PUSH FORWARD THESE

977
00:39:20,371 --> 00:39:22,006
INITIATIVES THAT WILL CHANGE

978
00:39:22,006 --> 00:39:22,206
LIVES.

979
00:39:22,206 --> 00:39:25,176
SO ON BEHALF OF THE ARTHRITIS

980
00:39:25,176 --> 00:39:26,043
COMMUNITY, ARTHRITIS FOUNDATION,

981
00:39:26,043 --> 00:39:27,378
I WANT TO THANK YOU PUBLICLY FOR

982
00:39:27,378 --> 00:39:27,745
THAT.

983
00:39:27,745 --> 00:39:29,580
>> THANK YOU VERY MUCH,
STEVE.

984
00:39:29,580 --> 00:39:30,981
WE GREATLY APPRECIATE YOUR

985
00:39:30,981 --> 00:39:33,284
SUPPORT AND THAT OF YOUR

986
00:39:33,284 --> 00:39:35,286
ORGANIZATION AND FOLKS YOU

987
00:39:35,286 --> 00:39:36,687
REPRESENT, ESPECIALLY AT THIS

988
00:39:36,687 --> 00:39:46,797
TIME. 

989
00:39:51,001 --> 00:39:51,602
SO THANK YOU.

990
00:39:51,602 --> 00:39:54,238
I DON'T SEE ANY OTHER HANDS UP.

991
00:39:54,238 --> 00:39:55,606
IF I'M MISSING YOUR HAND PLEASE

992
00:39:55,606 --> 00:40:06,016
FEEL FREE TO CHIME IN. 

993
00:40:13,691 --> 00:40:15,593
DARREN, ANY OTHER LOGISTICS YOU

994
00:40:15,593 --> 00:40:19,864
WANT TO REMIND FOLKS OF AT THIS

995
00:40:19,864 --> 00:40:21,398
TIME?

996
00:40:21,398 --> 00:40:23,901
>> I WILL JUST REEMPHASIZE
THE

997
00:40:23,901 --> 00:40:31,041
NIAMS COUNCIL MAIL, E-MAIL BOX,

998
00:40:31,041 --> 00:40:31,575
NIAMSCOUNCILMAIL@NIH.GOV.

999
00:40:31,575 --> 00:40:33,811
AGAIN, IF THERE ARE FOLLOW-UP

1000
00:40:33,811 --> 00:40:35,112
QUESTIONS OR COMMENTS, ABOUT

1001
00:40:35,112 --> 00:40:36,647
THIS COUNCIL MEETING, YOU CAN

1002
00:40:36,647 --> 00:40:40,518
SEND THEM TO THAT E-MAIL BOX. 

1003
00:40:40,518 --> 00:40:44,188
AND WE'LL TAKE THEM UNDER

1004
00:40:44,188 --> 00:40:44,522
CONSIDERATION.

1005
00:40:44,522 --> 00:40:45,523
>> AND DARREN, MAYBE NOW
WOULD

1006
00:40:45,523 --> 00:40:47,925
BE A GOOD TIME, WHY DON'T WE

1007
00:40:47,925 --> 00:40:50,094
SHARE THAT SLIDE THAT WE PUT

1008
00:40:50,094 --> 00:40:52,029
TOGETHER EARLIER.

1009
00:40:52,029 --> 00:40:55,900
SO, YOU KNOW, THERE'S A LOT OF

1010
00:40:55,900 --> 00:40:58,869
CHANGE UNDERWAY, AND WE CAN'T

1011
00:40:58,869 --> 00:41:01,739
SPEAK TO SOME OF THE CURRENT

1012
00:41:01,739 --> 00:41:03,607
DISCUSSIONS AND, YOU KNOW, ABOUT

1013
00:41:03,607 --> 00:41:05,242
POLICIES, ET CETERA.

1014
00:41:05,242 --> 00:41:07,711
BUT THERE ARE SOME PUBLICLY

1015
00:41:07,711 --> 00:41:12,383
AVAILABLE WEBSITES THAT PROVIDE

1016
00:41:12,383 --> 00:41:13,050
UPDATED INFORMATION, FOR

1017
00:41:13,050 --> 00:41:18,188
EXAMPLE, ABOUT NIH GRANTS AND

1018
00:41:18,188 --> 00:41:18,756
FUNDING INFORMATION, ABOUT

1019
00:41:18,756 --> 00:41:19,957
TERMINATED GRANTS, ET CETERA.

1020
00:41:19,957 --> 00:41:21,592
DARREN, DO YOU WANT TO SHARE

1021
00:41:21,592 --> 00:41:25,529
THAT SLIDE FOR FOLKS?

1022
00:41:25,529 --> 00:41:26,463
YEAH.

1023
00:41:26,463 --> 00:41:28,032
AND SO THIS IS PUBLICLY

1024
00:41:28,032 --> 00:41:30,668
AVAILABLE INFORMATION THAT WILL

1025
00:41:30,668 --> 00:41:33,203
BE UPDATED AS THINGS EVOLVE, AND

1026
00:41:33,203 --> 00:41:35,172
I WOULD ENCOURAGE YOU TO VISIT

1027
00:41:35,172 --> 00:41:37,007
THESE SITES IF YOU HAVE

1028
00:41:37,007 --> 00:41:40,411
QUESTIONS ABOUT SOME OF THESE

1029
00:41:40,411 --> 00:41:44,548
REALLY IMPORTANT ISSUES.

1030
00:41:44,548 --> 00:41:48,619
AND ALSO, JUST TO NOTE AS HAS

1031
00:41:48,619 --> 00:41:51,889
BEEN SHARED PUBLICLY, SOME

1032
00:41:51,889 --> 00:41:53,958
FUNDING OPPORTUNITIES HAVE BEEN

1033
00:41:53,958 --> 00:41:55,960
SUNSETTED, AND OTHERS HAVE BEEN

1034
00:41:55,960 --> 00:42:00,331
UPDATED TO ALIGN WITH AGENCY

1035
00:42:00,331 --> 00:42:00,864
PRIORITIES.

1036
00:42:00,864 --> 00:42:03,601
AND WE ENCOURAGE ALL POTENTIAL

1037
00:42:03,601 --> 00:42:05,803
APPLICANTS TO RE-READ FUNDING

1038
00:42:05,803 --> 00:42:07,471
OPPORTUNITIES CAREFULLY FOR ANY

1039
00:42:07,471 --> 00:42:09,073
POTENTIAL CHANGES PRIOR TO

1040
00:42:09,073 --> 00:42:12,209
SUBMISSION TO MAKE SURE THAT

1041
00:42:12,209 --> 00:42:14,678
THEIR APPLICATIONS -- YOU KNOW,

1042
00:42:14,678 --> 00:42:17,848
REFLECT ANY UPDATED GUIDANCE OR

1043
00:42:17,848 --> 00:42:19,617
LANGUAGE, AND ONE NOTE, FOR

1044
00:42:19,617 --> 00:42:23,854
EXAMPLE, IS APPLICATIONS NO

1045
00:42:23,854 --> 00:42:26,290
LONGER REQUIRE THE PEDP PLANS

1046
00:42:26,290 --> 00:42:27,491
FOR ENHANCING DIVERSE

1047
00:42:27,491 --> 00:42:29,460
PERSPECTIVES OR SOME OF THE

1048
00:42:29,460 --> 00:42:30,961
OTHER DIVERSITY STATEMENTS THAT

1049
00:42:30,961 --> 00:42:33,163
WERE REQUIRED IN SOME

1050
00:42:33,163 --> 00:42:33,731
APPLICATIONS PREVIOUSLY.

1051
00:42:33,731 --> 00:42:36,233
SO THAT HAS CHANGED.

1052
00:42:36,233 --> 00:42:37,968
ONCE AGAIN, UPDATES ABOUT NIH

1053
00:42:37,968 --> 00:42:39,970
GRANTS AND FUNDING INFORMATION

1054
00:42:39,970 --> 00:42:42,039
GENERALLY OR ABOUT ANY

1055
00:42:42,039 --> 00:42:44,341
TERMINATED GRANT STATUS IS

1056
00:42:44,341 --> 00:42:47,645
AVAILABLE AT THE WEBSITE LISTED

1057
00:42:47,645 --> 00:42:47,945
HERE.

1058
00:42:47,945 --> 00:42:49,179
WE CAN PUT MORE INFORMATION

1059
00:42:49,179 --> 00:42:52,249
ABOUT THOSE SITES IN E COUNCIL

1060
00:42:52,249 --> 00:42:59,123
BOOKS IF HELPFUL. 

1061
00:42:59,123 --> 00:43:01,525
I ALSO JUST WANT TO SAY AS

1062
00:43:01,525 --> 00:43:04,795
ALWAYS, AND TO THOSE NEW TO

1063
00:43:04,795 --> 00:43:07,598
COUNCIL, I WELCOME YOUR REACHING

1064
00:43:07,598 --> 00:43:09,533
OUT AT ANY TIME TO SUGGEST

1065
00:43:09,533 --> 00:43:12,269
TOPICS FOR DISCUSSION AT FUTURE

1066
00:43:12,269 --> 00:43:13,637
COUNCIL MEETINGS.

1067
00:43:13,637 --> 00:43:17,207
SOMETIMES THAT WILL PROMPT US TO

1068
00:43:17,207 --> 00:43:18,742
ACT, THOSE THAT ARE SUGGESTING

1069
00:43:18,742 --> 00:43:20,944
THE TOPIC, TO PERHAPS OPEN A

1070
00:43:20,944 --> 00:43:23,147
DISCUSSION ON THAT TOPIC.

1071
00:43:23,147 --> 00:43:24,782
SOMETIMES THOSE TOPICS TURN INTO

1072
00:43:24,782 --> 00:43:26,116
FORMAL WORKING GROUPS OF COUNCIL

1073
00:43:26,116 --> 00:43:28,318
AS WE'VE HAD FOR CLINICAL TRIALS

1074
00:43:28,318 --> 00:43:32,556
AND DATA SCIENCE.

1075
00:43:32,556 --> 00:43:34,758
SOMETIMES THEY TURN INTO

1076
00:43:34,758 --> 00:43:35,793
DETAILED PRESENTATIONS WITH

1077
00:43:35,793 --> 00:43:36,627
MULTIPLE PRESENTERS AS WE HAVE

1078
00:43:36,627 --> 00:43:38,395
IN THE LAST COUPLE OF YEARS

1079
00:43:38,395 --> 00:43:40,130
RELATED TO PATIENT ENGAGEMENT

1080
00:43:40,130 --> 00:43:41,231
AND COMMUNITY ENGAGEMENT.

1081
00:43:41,231 --> 00:43:44,835
SO WE REALLY LOOK TO YOU TO HELP

1082
00:43:44,835 --> 00:43:47,137
US UNDERSTAND WHAT ARE SOME OF

1083
00:43:47,137 --> 00:43:49,440
THE PRESSING BURNING ISSUES THAT

1084
00:43:49,440 --> 00:43:50,340
INVESTIGATORS ARE THINKING

1085
00:43:50,340 --> 00:43:50,974
ABOUT, OR IMPORTANT

1086
00:43:50,974 --> 00:43:54,144
OPPORTUNITIES THAT WE MIGHT BE

1087
00:43:54,144 --> 00:43:54,445
ADDRESSING.

1088
00:43:54,445 --> 00:43:55,479
IN ADDITION TO OTHER QUESTIONS

1089
00:43:55,479 --> 00:43:59,183
YOU MIGHT HAVE ABOUT ALL OF THE

1090
00:43:59,183 --> 00:44:00,084
TRANSITIONS HAPPENING NOW.

1091
00:44:00,084 --> 00:44:01,985
PLEASE FEEL FREE TO REACH OUT TO

1092
00:44:01,985 --> 00:44:05,756
ME OR DARREN SO THAT WE LEVERAGE

1093
00:44:05,756 --> 00:44:14,198
YOUR PERSPECTIVES IN FUTURE

1094
00:44:14,198 --> 00:44:14,832
COUNCIL MEETINGS.

1095
00:44:14,832 --> 00:44:16,667
AND FOR THOSE WHO ARE JOINING US

1096
00:44:16,667 --> 00:44:18,469
FOR THE FIRST TIME, THIS IS A

1097
00:44:18,469 --> 00:44:20,204
LITTLE BIT ATYPICAL.

1098
00:44:20,204 --> 00:44:22,506
USUALLY WE HAVE A LIVELY

1099
00:44:22,506 --> 00:44:25,342
DISCUSSION AND IT'S PERFECTLY

1100
00:44:25,342 --> 00:44:30,380
FINE THAT WE HAVE AN ABBREVIATED

1101
00:44:30,380 --> 00:44:32,149
MEETING TODAY, OUR MAKEUP FOR

1102
00:44:32,149 --> 00:44:34,084
JANUARY COUNCIL, SHORTER IN PART

1103
00:44:34,084 --> 00:44:38,288
FOR THAT REASON.

1104
00:44:38,288 --> 00:44:41,024
WE WEREN'T ABLE TO DO -- TO

1105
00:44:41,024 --> 00:44:41,892
PRESENT CONCEPT CLEARANCES, FOR

1106
00:44:41,892 --> 00:44:42,760
EXAMPLE, WHICH WOULD NORMALLY

1107
00:44:42,760 --> 00:44:44,928
HAVE HAPPENED DURING THE OPEN

1108
00:44:44,928 --> 00:44:49,867
SESSION OF COUNCIL. 

1109
00:44:49,867 --> 00:44:51,835
SO UNLESS THERE ARE ANY OTHER

1110
00:44:51,835 --> 00:44:53,570
QUESTIONS, I DON'T WANT TO KEEP

1111
00:44:53,570 --> 00:44:55,339
YOU ANY LONGER THAN IS NECESSAR.

1112
00:44:55,339 --> 00:44:57,541
PLEASE FEEL FREE TO REACH OUT.

1113
00:44:57,541 --> 00:44:59,276
THANK YOU FOR JOINING US.

1114
00:44:59,276 --> 00:45:00,944
WELCOME TO OUR NEW MEMBERS AND

1115
00:45:00,944 --> 00:45:06,416
OUR AD HOCS. 

1116
00:45:06,416 --> 00:45:11,221
I THINK THE AD HOCS WILL JOIN US

1117
00:45:11,221 --> 00:45:13,724
IN JUNE FOR TYPICAL COUNCIL

1118
00:45:13,724 --> 00:45:14,158
MEETING.

1119
00:45:14,158 --> 00:45:15,392
FAREWELL TO GAYLE AND THANKS

1120
00:45:15,392 --> 00:45:17,895
AGAIN TO MARY AND THANKS TO

1121
00:45:17,895 --> 00:45:20,397
DARREN AND SHALANDA FOR

1122
00:45:20,397 --> 00:45:21,932
ORGANIZING TODAY'S MEETING.

1123
00:45:21,932 --> 00:45:24,134
I THINK I'M ACTUALLY SUPPOSED TO

1124
00:45:24,134 --> 00:45:26,737
FORMALLY CLOSE THE MEETING.

1125
00:45:26,737 --> 00:45:32,442
SO, LAST CALL FOR ANY QUESTIONS.

1126
00:45:32,442 --> 00:45:36,380
AND SEEING NO HANDS, THIS

1127
00:45:36,380 --> 00:45:38,248
CONCLUDES THE INSTITUTE'S

1128
00:45:38,248 --> 00:45:39,583
116th ADVISORY COUNCIL

1129
00:45:39,583 --> 00:45:39,917
MEETING.

1130
00:45:39,917 --> 00:45:41,318
WE GREATLY APPRECIATE WHAT WE'VE

1131
00:45:41,318 --> 00:45:43,954
HEARD AND INVITE YOUR FEEDBACK

1132
00:45:43,954 --> 00:45:45,923
BETWEEN MEETINGS AS WELL, AS I

1133
00:45:45,923 --> 00:45:46,456
JUST MENTIONED.

1134
00:45:46,456 --> 00:45:48,225
PLEASE FEEL FREE TO REACH OUT TO

1135
00:45:48,225 --> 00:45:50,060
DARREN OR ME DIRECTLY FOR ANY

1136
00:45:50,060 --> 00:45:52,095
IDEAS FOR FUTURE TOPICS THAT YOU

1137
00:45:52,095 --> 00:45:54,331
WANT TO BRING TO THE ATTENTION

1138
00:45:54,331 --> 00:45:55,432
OF THE INSTITUTE.

1139
00:45:55,432 --> 00:45:58,068
SO, THANK YOU AGAIN FOR JOINING

1140
00:45:58,068 --> 00:45:58,235
US.

1141
00:45:58,235 --> 00:46:02,306
I THINK ON THAT NOTE WE'LL END

1142
00:46:02,306 --> 00:46:03,473
THIS MEETING.

1143
00:46:03,473 --> 00:46:03,740
THANK YOU.

1144
00:46:03,740 --> 00:46:06,510
[END OF PROGRAM]

1145
00:46:06,510 --> 00:46:12,549
 

1146
00:46:12,549 --> 00:46:22,593